Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6ks8_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N PRO 1.A O no hydrogen 3.180 N/A LYS 6.A N GLN 2.A O no hydrogen 2.643 N/A ALA 7.A N GLU 3.A O no hydrogen 3.097 N/A ASN 8.A N VAL 4.A O no hydrogen 2.941 N/A ILE 9.A N ARG 5.A O no hydrogen 3.062 N/A ILE 10.A N LYS 6.A O no hydrogen 3.114 N/A ALA 11.A N ALA 7.A O no hydrogen 2.989 N/A ALA 12.A N ASN 8.A O no hydrogen 3.092 N/A ARG 13.A N ILE 9.A O no hydrogen 2.809 N/A SER 14.A N ILE 10.A O no hydrogen 3.012 N/A SER 14.A OG ILE 10.A O no hydrogen 3.347 N/A SER 14.A OG ALA 11.A O no hydrogen 2.548 N/A VAL 15.A N ALA 12.A O no hydrogen 3.125 N/A ARG 20.A N ALA 16.A O no hydrogen 3.109 N/A ARG 20.A NE THR 417.A OG1 no hydrogen 3.198 N/A THR 21.A OG1 ALA 18.A O no hydrogen 2.560 N/A SER 22.A N ILE 19.A O no hydrogen 3.151 N/A SER 22.A OG MET 28.A O no hydrogen 2.699 N/A GLY 27.A N GLY 24.A O no hydrogen 3.196 N/A MET 28.A N THR 21.A O no hydrogen 2.368 N/A THR 34.A N GLU 38.A O no hydrogen 3.102 N/A THR 34.A OG1 GLU 38.A O no hydrogen 2.913 N/A GLY 37.A N THR 34.A O no hydrogen 3.031 N/A ILE 40.A N ILE 32.A O no hydrogen 3.410 N/A ASP 44.A N SER 42.A OG no hydrogen 3.315 N/A HIS 46.A N ASP 44.A OD1 no hydrogen 3.092 N/A THR 47.A OG1 ASP 44.A OD2 no hydrogen 2.800 N/A ILE 48.A N ASP 44.A O no hydrogen 3.329 N/A LEU 49.A N GLY 45.A O no hydrogen 3.379 N/A LYS 50.A N HIS 46.A O no hydrogen 3.222 N/A LYS 50.A N THR 47.A O no hydrogen 3.300 N/A GLN 51.A N THR 47.A O no hydrogen 3.289 N/A HIS 56.A NE2 ASN 8.A OD1 no hydrogen 2.500 N/A ARG 60.A N PRO 57.A O no hydrogen 3.047 N/A ARG 60.A NE ILE 54.A O no hydrogen 2.529 N/A ARG 60.A NH2 ILE 54.A O no hydrogen 2.977 N/A MET 61.A N VAL 58.A O no hydrogen 3.249 N/A VAL 63.A N ARG 60.A O no hydrogen 3.103 N/A VAL 65.A N MET 61.A O no hydrogen 3.070 N/A SER 66.A N LEU 62.A O no hydrogen 3.060 N/A SER 66.A OG HIS 46.A ND1 no hydrogen 3.412 N/A SER 66.A OG LEU 62.A O no hydrogen 3.332 N/A SER 66.A OG VAL 63.A O no hydrogen 2.798 N/A ALA 67.A N VAL 63.A O no hydrogen 2.829 N/A ALA 68.A N GLU 64.A O no hydrogen 2.962 N/A GLN 69.A N VAL 65.A O no hydrogen 2.968 N/A GLN 69.A NE2 ASP 75.A O no hydrogen 3.400 N/A GLN 69.A NE2 SER 458.A OG no hydrogen 2.490 N/A ASP 70.A N SER 66.A O no hydrogen 3.265 N/A SER 71.A N ALA 67.A O no hydrogen 3.021 N/A SER 71.A OG ALA 67.A O no hydrogen 2.746 N/A GLY 74.A N GLN 69.A O no hydrogen 3.014 N/A VAL 80.A N GLY 76.A O no hydrogen 3.085 N/A ILE 82.A N THR 78.A O no hydrogen 3.478 N/A LEU 83.A N SER 79.A O no hydrogen 2.942 N/A THR 84.A N VAL 80.A O no hydrogen 3.155 N/A THR 84.A OG1 VAL 80.A O no hydrogen 2.900 N/A GLY 85.A N VAL 81.A O no hydrogen 3.139 N/A ALA 86.A N ILE 82.A O no hydrogen 3.063 N/A LEU 87.A N LEU 83.A O no hydrogen 3.371 N/A LEU 88.A N THR 84.A O no hydrogen 3.153 N/A GLY 89.A N GLY 85.A O no hydrogen 2.974 N/A ALA 90.A N ALA 86.A O no hydrogen 3.103 N/A ALA 91.A N LEU 87.A O no hydrogen 2.983 N/A GLU 92.A N LEU 88.A O no hydrogen 3.248 N/A ARG 93.A NH2 GLU 406.A OE1 no hydrogen 3.386 N/A LEU 94.A N ALA 91.A O no hydrogen 3.221 N/A LEU 95.A N ALA 91.A O no hydrogen 3.395 N/A LYS 97.A N LEU 94.A O no hydrogen 3.280 N/A GLY 98.A N LEU 95.A O no hydrogen 3.341 N/A ILE 99.A N LEU 94.A O no hydrogen 3.265 N/A THR 102.A N HIS 100.A ND1 no hydrogen 3.018 N/A ILE 104.A N HIS 100.A O no hydrogen 3.345 N/A ALA 105.A N PRO 101.A O no hydrogen 2.859 N/A ASP 106.A N THR 102.A O no hydrogen 2.837 N/A SER 107.A N ILE 103.A O no hydrogen 2.837 N/A SER 107.A OG ILE 103.A O no hydrogen 2.770 N/A PHE 108.A N ILE 104.A O no hydrogen 3.274 N/A GLN 109.A N ASP 106.A O no hydrogen 3.361 N/A ALA 111.A N SER 107.A O no hydrogen 3.159 N/A ALA 112.A N PHE 108.A O no hydrogen 2.952 N/A LYS 113.A N GLN 109.A O no hydrogen 3.113 N/A ARG 114.A N SER 110.A O no hydrogen 3.144 N/A SER 115.A N ALA 111.A O no hydrogen 3.275 N/A SER 115.A OG ALA 111.A O no hydrogen 2.492 N/A VAL 116.A N LYS 113.A O no hydrogen 3.272 N/A ILE 118.A N ARG 114.A O no hydrogen 3.092 N/A LEU 119.A N SER 115.A O no hydrogen 2.899 N/A LEU 120.A N VAL 116.A O no hydrogen 3.070 N/A GLU 121.A N ILE 118.A O no hydrogen 3.091 N/A MET 122.A N ILE 118.A O no hydrogen 3.482 N/A SER 129.A N SER 127.A OG no hydrogen 3.344 N/A ASP 130.A N SER 127.A O no hydrogen 3.501 N/A GLU 132.A N ASP 130.A OD1 no hydrogen 3.117 N/A GLN 133.A NE2 GLN 133.A O no hydrogen 3.353 N/A VAL 135.A N ARG 131.A O no hydrogen 3.120 N/A ARG 136.A N GLU 132.A O no hydrogen 3.466 N/A ALA 137.A N GLN 133.A O no hydrogen 3.293 N/A ALA 138.A N LEU 134.A O no hydrogen 3.217 N/A SER 139.A N VAL 135.A O no hydrogen 2.912 N/A THR 140.A N ARG 136.A O no hydrogen 3.270 N/A THR 140.A OG1 ARG 136.A O no hydrogen 2.754 N/A THR 140.A OG1 ALA 137.A O no hydrogen 3.533 N/A THR 140.A OG1 HIS 448.A O no hydrogen 3.240 N/A LEU 142.A N SER 139.A O no hydrogen 3.198 N/A SER 143.A N THR 140.A O no hydrogen 3.400 N/A SER 143.A OG THR 140.A O no hydrogen 3.059 N/A LYS 145.A N LEU 142.A O no hydrogen 3.119 N/A SER 151.A N SER 148.A O no hydrogen 3.279 N/A SER 151.A OG SER 148.A O no hydrogen 2.498 N/A ALA 155.A N SER 152.A O no hydrogen 3.331 N/A ALA 158.A N LEU 154.A O no hydrogen 3.206 N/A VAL 159.A N ALA 155.A O no hydrogen 3.275 N/A ASP 160.A N PRO 156.A O no hydrogen 3.207 N/A SER 161.A OG ALA 158.A O no hydrogen 2.759 N/A VAL 162.A N VAL 159.A O no hydrogen 3.087 N/A LEU 163.A N VAL 159.A O no hydrogen 3.252 N/A ILE 165.A N VAL 162.A O no hydrogen 2.909 N/A SER 166.A OG VAL 162.A O no hydrogen 2.514 N/A ASN 176.A N ASP 174.A OD1 no hydrogen 3.228 N/A ASP 177.A N ASP 174.A O no hydrogen 3.483 N/A ILE 178.A N LEU 175.A O no hydrogen 3.308 N/A ARG 179.A N VAL 339.A O no hydrogen 3.103 N/A VAL 181.A N VAL 341.A O no hydrogen 3.347 N/A LYS 183.A N ILE 343.A O no hydrogen 2.730 N/A GLY 185.A N GLY 345.A O no hydrogen 2.487 N/A THR 191.A OG1 ILE 188.A O no hydrogen 3.322 N/A ILE 194.A N SER 340.A O no hydrogen 2.754 N/A THR 200.A OG1 GLU 284.A OE2 no hydrogen 2.740 N/A THR 211.A OG1 PRO 210.A O no hydrogen 2.297 N/A LYS 213.A N VAL 314.A O no hydrogen 2.704 N/A LYS 215.A N ASP 312.A O no hydrogen 2.553 N/A ALA 216.A N ALA 311.A O no hydrogen 2.863 N/A GLN 222.A N ILE 297.A O no hydrogen 2.439 N/A GLN 224.A NE2 ASP 259.A O no hydrogen 2.344 N/A ILE 225.A N ALA 260.A O no hydrogen 2.939 N/A TYR 234.A N GLU 230.A O no hydrogen 3.210 N/A LEU 235.A N GLU 231.A O no hydrogen 3.222 N/A LEU 236.A N ARG 232.A O no hydrogen 2.835 N/A ASN 237.A N ALA 233.A O no hydrogen 3.074 N/A CYS 239.A N LEU 235.A O no hydrogen 3.438 N/A CYS 239.A SG LEU 235.A O no hydrogen 3.355 N/A LYS 240.A N LEU 236.A O no hydrogen 2.792 N/A LYS 241.A N ASN 237.A O no hydrogen 3.448 N/A LYS 243.A N CYS 239.A O no hydrogen 3.077 N/A LYS 244.A N LYS 240.A O no hydrogen 3.217 N/A LYS 246.A N LYS 243.A O no hydrogen 3.126 N/A CYS 247.A N ILE 242.A O no hydrogen 3.486 N/A CYS 247.A SG LYS 217.A O no hydrogen 3.834 N/A CYS 247.A SG VAL 249.A O no hydrogen 3.175 N/A ASN 248.A ND2 LYS 215.A O no hydrogen 2.966 N/A VAL 249.A N LYS 217.A O no hydrogen 3.277 N/A LEU 250.A N MET 275.A O no hydrogen 2.678 N/A ILE 252.A N VAL 277.A O no hydrogen 3.381 N/A LYS 254.A N ILE 280.A O no hydrogen 2.981 N/A ARG 258.A NH1 LEU 257.A O no hydrogen 3.006 N/A LEU 264.A N ASN 262.A OD1 no hydrogen 3.150 N/A ALA 265.A N ASN 262.A O no hydrogen 3.225 N/A LEU 266.A N ASN 262.A O no hydrogen 3.279 N/A HIS 267.A N ASP 263.A O no hydrogen 3.257 N/A PHE 268.A N LEU 264.A O no hydrogen 3.299 N/A LEU 269.A N ALA 265.A O no hydrogen 3.101 N/A SER 270.A OG LEU 266.A O no hydrogen 2.606 N/A ASN 273.A N SER 270.A O no hydrogen 3.286 N/A ILE 274.A N LEU 269.A O no hydrogen 3.101 N/A MET 275.A N ASN 248.A O no hydrogen 2.801 N/A VAL 277.A N LEU 250.A O no hydrogen 3.069 N/A GLU 284.A N GLU 281.A O no hydrogen 3.238 N/A ILE 285.A N ARG 282.A O no hydrogen 3.346 N/A LEU 288.A N GLU 284.A O no hydrogen 3.118 N/A SER 289.A N ILE 285.A O no hydrogen 3.215 N/A SER 289.A OG ILE 285.A O no hydrogen 3.402 N/A SER 289.A OG GLU 286.A O no hydrogen 3.248 N/A LEU 292.A N LEU 288.A O no hydrogen 3.294 N/A CYS 294.A SG LEU 288.A O no hydrogen 3.544 N/A ILE 300.A N ASP 299.A OD1 no hydrogen 2.423 N/A PHE 303.A N ILE 300.A O no hydrogen 3.422 N/A ARG 307.A NH1 THR 304.A OG1 no hydrogen 2.583 N/A LEU 308.A N GLU 305.A O no hydrogen 3.254 N/A ALA 311.A N ALA 216.A O no hydrogen 2.764 N/A ASP 312.A N THR 328.A O no hydrogen 2.981 N/A VAL 314.A N LYS 213.A O no hydrogen 2.773 N/A ILE 317.A N ILE 324.A O no hydrogen 2.915 N/A SER 322.A N ASP 318.A OD1 no hydrogen 2.610 N/A SER 322.A OG SER 319.A O no hydrogen 2.274 N/A LYS 323.A N ASP 318.A OD1 no hydrogen 3.191 N/A ILE 324.A N ILE 317.A O no hydrogen 2.951 N/A ARG 326.A N GLU 315.A O no hydrogen 3.393 N/A ARG 326.A NE GLU 315.A OE2 no hydrogen 3.150 N/A ARG 326.A NH2 GLU 315.A OE2 no hydrogen 2.439 N/A VAL 327.A N VAL 197.A O no hydrogen 3.243 N/A THR 328.A N LEU 313.A O no hydrogen 3.400 N/A THR 328.A OG1 LEU 313.A O no hydrogen 3.321 N/A ASN 332.A ND2 LEU 292.A O no hydrogen 3.201 N/A ASN 334.A N ASN 332.A OD1 no hydrogen 2.910 N/A ALA 335.A N ASN 332.A O no hydrogen 3.334 N/A THR 338.A N ARG 336.A O no hydrogen 2.733 N/A VAL 339.A N ASP 177.A O no hydrogen 2.939 N/A SER 340.A N ILE 194.A O no hydrogen 3.241 N/A VAL 341.A N ARG 179.A O no hydrogen 3.278 N/A VAL 342.A N GLU 192.A O no hydrogen 3.366 N/A ILE 343.A N VAL 181.A O no hydrogen 2.848 N/A GLY 345.A N GLY 185.A O no hydrogen 2.766 N/A ILE 350.A N ASN 347.A O no hydrogen 3.223 N/A THR 354.A N ILE 350.A O no hydrogen 2.904 N/A THR 354.A OG1 ILE 350.A O no hydrogen 2.835 N/A GLU 355.A N ILE 351.A O no hydrogen 3.329 N/A ARG 356.A N ASP 352.A O no hydrogen 3.158 N/A SER 357.A N GLU 353.A O no hydrogen 2.851 N/A SER 357.A OG GLU 353.A O no hydrogen 2.703 N/A LEU 358.A N THR 354.A O no hydrogen 3.205 N/A LEU 358.A N GLU 355.A O no hydrogen 3.058 N/A HIS 359.A N GLU 355.A O no hydrogen 3.381 N/A LEU 362.A N LEU 358.A O no hydrogen 3.041 N/A CYS 363.A N HIS 359.A O no hydrogen 2.999 N/A CYS 363.A SG HIS 359.A O no hydrogen 3.150 N/A VAL 364.A N ASP 360.A O no hydrogen 3.291 N/A ILE 365.A N ALA 361.A O no hydrogen 3.444 N/A ARG 366.A N LEU 362.A O no hydrogen 2.878 N/A CYS 367.A N CYS 363.A O no hydrogen 2.989 N/A CYS 367.A SG ALA 73.A O no hydrogen 3.410 N/A CYS 367.A SG CYS 363.A O no hydrogen 3.153 N/A VAL 369.A N ILE 365.A O no hydrogen 3.148 N/A LYS 370.A N ARG 366.A O no hydrogen 3.152 N/A GLU 371.A N CYS 367.A O no hydrogen 3.042 N/A LEU 374.A N HIS 124.A O no hydrogen 3.249 N/A ILE 383.A N GLY 379.A O no hydrogen 3.296 N/A GLU 384.A N ALA 380.A O no hydrogen 3.107 N/A ILE 385.A N PRO 381.A O no hydrogen 3.219 N/A SER 386.A N GLU 382.A O no hydrogen 3.233 N/A SER 386.A OG ALA 408.A O no hydrogen 2.538 N/A ARG 387.A N ILE 383.A O no hydrogen 3.119 N/A ARG 387.A NE GLU 438.A OE2 no hydrogen 2.855 N/A ARG 388.A N GLU 384.A O no hydrogen 3.414 N/A LEU 389.A N ILE 385.A O no hydrogen 3.179 N/A SER 390.A N ARG 387.A O no hydrogen 3.164 N/A SER 390.A OG SER 386.A O no hydrogen 3.042 N/A GLU 392.A N ARG 388.A O no hydrogen 3.198 N/A ALA 393.A N LEU 389.A O no hydrogen 3.027 N/A ARG 394.A N LYS 391.A O no hydrogen 3.376 N/A SER 395.A N GLU 392.A O no hydrogen 3.202 N/A SER 395.A OG GLU 392.A O no hydrogen 2.686 N/A SER 395.A OG GLU 392.A OE1 no hydrogen 3.476 N/A MET 396.A N ALA 393.A O no hydrogen 3.399 N/A PHE 402.A N VAL 399.A O no hydrogen 3.243 N/A ILE 403.A N GLN 400.A O no hydrogen 2.773 N/A TRP 404.A N GLN 400.A O no hydrogen 2.954 N/A GLU 406.A N PHE 402.A O no hydrogen 3.407 N/A PHE 407.A N ILE 403.A O no hydrogen 2.711 N/A ALA 408.A N TRP 404.A O no hydrogen 3.274 N/A SER 409.A N GLN 405.A O no hydrogen 3.310 N/A SER 409.A OG GLN 405.A O no hydrogen 3.240 N/A ALA 410.A N GLU 406.A O no hydrogen 3.220 N/A LEU 411.A N ALA 408.A O no hydrogen 3.346 N/A GLU 412.A N SER 409.A O no hydrogen 3.363 N/A THR 416.A N GLU 412.A O no hydrogen 3.255 N/A THR 416.A OG1 GLU 412.A O no hydrogen 2.737 N/A THR 417.A N VAL 413.A O no hydrogen 2.804 N/A THR 417.A OG1 VAL 413.A O no hydrogen 2.807 N/A LEU 418.A N ILE 414.A O no hydrogen 3.249 N/A ALA 419.A N PRO 415.A O no hydrogen 3.319 N/A GLU 420.A N THR 416.A O no hydrogen 3.015 N/A ASN 421.A N THR 417.A O no hydrogen 2.899 N/A ASN 421.A ND2 ARG 20.A O no hydrogen 2.615 N/A ASN 421.A ND2 LEU 23.A O no hydrogen 2.958 N/A ALA 422.A N LEU 418.A O no hydrogen 3.319 N/A GLY 423.A N GLU 420.A O no hydrogen 3.056 N/A VAL 429.A N ASN 425.A O no hydrogen 3.176 N/A VAL 430.A N SER 426.A O no hydrogen 3.136 N/A THR 431.A N ILE 427.A O no hydrogen 3.026 N/A THR 431.A OG1 ILE 427.A O no hydrogen 2.734 N/A THR 431.A OG1 LYS 428.A O no hydrogen 3.308 N/A GLU 432.A N LYS 428.A O no hydrogen 3.244 N/A LEU 433.A N VAL 429.A O no hydrogen 2.927 N/A ARG 434.A N VAL 430.A O no hydrogen 3.111 N/A SER 435.A N THR 431.A O no hydrogen 3.082 N/A SER 435.A OG THR 431.A O no hydrogen 2.513 N/A LYS 436.A N GLU 432.A O no hydrogen 3.496 N/A ASN 439.A N LYS 436.A O no hydrogen 3.177 N/A GLY 440.A N LYS 436.A O no hydrogen 2.960 N/A HIS 448.A N TYR 445.A O no hydrogen 3.250 N/A ILE 449.A N THR 444.A O no hydrogen 3.386 N/A GLN 451.A N ILE 375.A O no hydrogen 3.140 N/A THR 457.A N VAL 453.A O no hydrogen 2.706 N/A THR 457.A OG1 GLU 371.A OE1 no hydrogen 3.440 N/A THR 457.A OG1 VAL 453.A O no hydrogen 2.842 N/A SER 458.A N LEU 454.A O no hydrogen 2.716 N/A SER 458.A OG LEU 454.A O no hydrogen 2.851 N/A SER 458.A OG VAL 455.A O no hydrogen 3.342 N/A ALA 459.A N VAL 455.A O no hydrogen 3.054 N/A THR 461.A N THR 457.A O no hydrogen 3.127 N/A THR 461.A OG1 THR 457.A O no hydrogen 3.046 N/A LEU 462.A N SER 458.A O no hydrogen 2.837 N/A ALA 463.A N ALA 459.A O no hydrogen 3.357 N/A SER 464.A N THR 461.A O no hydrogen 3.276 N/A SER 464.A OG THR 461.A O no hydrogen 2.388 N/A CYS 466.A N LEU 462.A O no hydrogen 3.056 N/A VAL 467.A N ALA 463.A O no hydrogen 3.249 N/A LYS 468.A N SER 464.A O no hydrogen 3.250 N/A SER 469.A N GLU 465.A O no hydrogen 2.764 N/A SER 469.A OG GLU 465.A O no hydrogen 3.118 N/A SER 469.A OG CYS 466.A O no hydrogen 2.806 N/A ILE 470.A N CYS 466.A O no hydrogen 3.164 N/A ILE 470.A N VAL 467.A O no hydrogen 3.325 N/A LEU 471.A N VAL 467.A O no hydrogen 3.412 N/A ARG 472.A N LYS 468.A O no hydrogen 3.268 N/A ILE 473.A N ILE 470.A O no hydrogen 2.994 N/A ILE 476.A N ASP 475.A OD1 no hydrogen 2.436 N/A