Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6mkm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG GLU 3.A OE2 no hydrogen 3.533 N/A ALA 6.A N LYS 239.A O no hydrogen 3.339 N/A TYR 8.A OH ASP 10.A OD1 no hydrogen 2.552 N/A GLN 14.A N ASP 260.A OD2 no hydrogen 2.798 N/A GLN 14.A NE2 THR 16.A O no hydrogen 3.018 N/A SER 17.A N LYS 21.A O no hydrogen 2.817 N/A SER 17.A OG SER 19.A OG no hydrogen 3.060 N/A SER 17.A OG LYS 21.A O no hydrogen 3.484 N/A SER 19.A N SER 17.A OG no hydrogen 3.261 N/A SER 19.A OG SER 17.A OG no hydrogen 3.060 N/A GLY 20.A N SER 17.A O no hydrogen 2.955 N/A LYS 21.A N SER 17.A OG no hydrogen 3.191 N/A ALA 23.A N LYS 15.A O no hydrogen 2.696 N/A THR 24.A N LEU 279.A O no hydrogen 2.735 N/A THR 24.A OG1 LEU 279.A O no hydrogen 3.466 N/A THR 24.A OG1 LEU 281.A O no hydrogen 2.787 N/A LEU 25.A N LEU 279.A O no hydrogen 3.039 N/A LYS 26.A N ASP 53.A OD2 no hydrogen 2.810 N/A LYS 26.A NZ GLU 50.A O no hydrogen 2.831 N/A LYS 26.A NZ GLU 50.A OE1 no hydrogen 2.877 N/A ILE 27.A N LEU 277.A O no hydrogen 2.956 N/A CYS 28.A N ILE 54.A O no hydrogen 2.858 N/A CYS 28.A SG ILE 275.A O no hydrogen 3.675 N/A CYS 28.A SG THR 276.A OG1 no hydrogen 3.677 N/A SER 29.A N ILE 275.A O no hydrogen 2.852 N/A TRP 30.A N CYS 56.A O no hydrogen 2.888 N/A TRP 30.A NE1 HIS 272.A O no hydrogen 2.985 N/A ASN 31.A ND2 GLU 59.A OE2 no hydrogen 2.927 N/A ASN 31.A ND2 ASP 173.A OD2 no hydrogen 2.785 N/A VAL 32.A N GLN 58.A O no hydrogen 2.945 N/A ASP 33.A N ASN 31.A OD1 no hydrogen 3.084 N/A GLY 34.A N GLU 59.A O no hydrogen 2.700 N/A LEU 35.A N THR 60.A O no hydrogen 2.886 N/A ARG 36.A NH1 LYS 66.A O no hydrogen 3.235 N/A ARG 36.A NH2 LYS 66.A O no hydrogen 2.914 N/A TRP 38.A N GLY 34.A O no hydrogen 2.838 N/A ILE 39.A N LEU 35.A O no hydrogen 2.915 N/A LYS 40.A N ARG 36.A O no hydrogen 3.080 N/A LYS 41.A N ALA 37.A O no hydrogen 3.065 N/A LYS 41.A N TRP 38.A O no hydrogen 3.016 N/A LYS 42.A N ILE 39.A O no hydrogen 3.011 N/A LYS 42.A NZ ASP 45.A OD2 no hydrogen 3.006 N/A GLY 43.A N TRP 38.A O no hydrogen 2.951 N/A ASP 45.A N LYS 42.A O no hydrogen 3.040 N/A VAL 47.A N GLY 43.A O no hydrogen 3.419 N/A LYS 48.A N LEU 44.A O no hydrogen 2.975 N/A GLU 49.A N ASP 45.A O no hydrogen 3.159 N/A GLU 50.A N TRP 46.A O no hydrogen 2.696 N/A ALA 51.A N VAL 47.A O no hydrogen 2.808 N/A ASP 53.A N LYS 26.A O no hydrogen 2.749 N/A ILE 54.A N LYS 26.A O no hydrogen 3.264 N/A LEU 55.A N LEU 97.A O no hydrogen 2.739 N/A CYS 56.A N CYS 28.A O no hydrogen 2.750 N/A LEU 57.A N GLY 95.A O no hydrogen 2.843 N/A GLN 58.A N TRP 30.A O no hydrogen 2.924 N/A GLN 58.A NE2 SER 29.A OG no hydrogen 3.032 N/A GLN 58.A NE2 THR 132.A OG1 no hydrogen 2.995 N/A THR 60.A N GLY 93.A O no hydrogen 3.083 N/A THR 60.A OG1 CYS 62.A O.B no hydrogen 3.462 N/A LYS 61.A N SER 92.A O no hydrogen 2.731 N/A LYS 61.A NZ ASP 33.A OD1 no hydrogen 3.205 N/A CYS 62.A SG.A THR 60.A O no hydrogen 3.510 N/A CYS 62.A SG.B SER 63.A O no hydrogen 3.372 N/A CYS 62.A SG.B LYS 66.A O no hydrogen 2.797 N/A LYS 66.A N SER 63.A O no hydrogen 2.993 N/A GLU 70.A N GLU 70.A OE1 no hydrogen 2.365 N/A LEU 71.A N PRO 68.A O no hydrogen 3.155 N/A GLN 72.A N ALA 69.A O no hydrogen 2.971 N/A GLU 73.A N GLU 70.A O no hydrogen 3.100 N/A LEU 74.A N LEU 71.A O no hydrogen 3.349 N/A LEU 77.A N LEU 74.A O no hydrogen 2.932 N/A HIS 79.A N SER 98.A O no hydrogen 3.160 N/A GLN 80.A NE2 LEU 71.A O no hydrogen 3.448 N/A GLN 80.A NE2 LEU 77.A O no hydrogen 2.889 N/A TYR 81.A N LEU 96.A O no hydrogen 2.864 N/A SER 83.A N VAL 94.A O no hydrogen 2.932 N/A SER 86.A N GLN 116.A O no hydrogen 3.017 N/A SER 86.A OG GLN 116.A O no hydrogen 3.287 N/A SER 86.A OG GLN 116.A OE1 no hydrogen 2.725 N/A LYS 88.A N PRO 85.A O no hydrogen 3.041 N/A GLU 89.A N ASP 87.A OD1 no hydrogen 2.780 N/A TYR 91.A OH ASP 87.A OD2 no hydrogen 2.907 N/A SER 92.A OG GLU 117.A O no hydrogen 2.687 N/A SER 92.A OG GLY 118.A O no hydrogen 3.498 N/A VAL 94.A N SER 83.A O no hydrogen 2.990 N/A GLY 95.A N LEU 57.A O no hydrogen 2.792 N/A LEU 96.A N TYR 81.A O no hydrogen 2.860 N/A LEU 97.A N LEU 55.A O no hydrogen 2.793 N/A SER 98.A N HIS 79.A O no hydrogen 2.781 N/A SER 98.A OG GLN 100.A O no hydrogen 2.655 N/A ARG 99.A N ASP 53.A O no hydrogen 2.846 N/A ARG 99.A NE ASP 53.A OD1 no hydrogen 2.889 N/A ARG 99.A NH2 ASP 53.A OD1 no hydrogen 3.553 N/A LEU 103.A N GLU 124.A O no hydrogen 2.685 N/A SER 106.A N.A VAL 122.A O no hydrogen 2.907 N/A SER 106.A N.B VAL 122.A O no hydrogen 2.894 N/A GLY 108.A N VAL 120.A O no hydrogen 3.023 N/A ILE 109.A N ASP 115.A OD1 no hydrogen 2.821 N/A ASP 111.A N ASP 115.A OD2 no hydrogen 2.920 N/A GLU 113.A N ASP 111.A OD1 no hydrogen 3.363 N/A HIS 114.A N ASP 111.A O no hydrogen 2.805 N/A HIS 114.A ND1 TYR 147.A OH no hydrogen 2.879 N/A ASP 115.A N GLU 112.A O no hydrogen 3.344 N/A GLN 116.A NE2 GLU 112.A O no hydrogen 2.655 N/A ARG 119.A NE GLU 117.A OE1 no hydrogen 2.907 N/A ARG 119.A NH1 TYR 134.A O no hydrogen 2.830 N/A ARG 119.A NH2 GLU 117.A OE1 no hydrogen 3.029 N/A ILE 121.A N THR 132.A O no hydrogen 3.106 N/A VAL 122.A N SER 106.A O.A no hydrogen 2.741 N/A VAL 122.A N SER 106.A O.B no hydrogen 2.929 N/A ALA 123.A N LEU 130.A O no hydrogen 2.721 N/A GLU 124.A N LYS 104.A O no hydrogen 2.931 N/A PHE 125.A N PHE 128.A O no hydrogen 2.844 N/A VAL 129.A N PRO 167.A O no hydrogen 2.842 N/A LEU 130.A N ALA 123.A O no hydrogen 2.797 N/A VAL 131.A N VAL 169.A O no hydrogen 2.818 N/A THR 132.A N ILE 121.A O no hydrogen 2.991 N/A THR 132.A OG1 CYS 171.A O no hydrogen 3.292 N/A ALA 133.A N CYS 171.A O no hydrogen 2.988 N/A TYR 134.A N ARG 119.A O no hydrogen 2.898 N/A VAL 135.A N ASP 173.A O no hydrogen 3.022 N/A ASN 137.A ND2 ASN 175.A OD1 no hydrogen 3.293 N/A GLY 139.A N ASN 137.A OD1 no hydrogen 2.834 N/A LEU 142.A N GLY 139.A O no hydrogen 2.817 N/A ARG 144.A N ALA 138.A O no hydrogen 2.802 N/A ARG 144.A NH1 GLU 117.A OE1 no hydrogen 3.160 N/A ARG 144.A NH2 GLU 117.A OE1 no hydrogen 3.458 N/A ARG 144.A NH2 GLU 117.A OE2 no hydrogen 2.798 N/A LEU 145.A N LEU 142.A O no hydrogen 3.128 N/A TYR 147.A OH HIS 114.A ND1 no hydrogen 2.879 N/A ARG 148.A N ARG 144.A O no hydrogen 2.843 N/A ARG 148.A NE ASP 152.A OD1 no hydrogen 2.857 N/A ARG 148.A NH1 PRO 136.A O no hydrogen 3.006 N/A ARG 148.A NH1 ASN 175.A O no hydrogen 3.018 N/A ARG 148.A NH2 ASN 175.A O no hydrogen 3.053 N/A GLN 149.A N LEU 145.A O no hydrogen 3.009 N/A ARG 150.A N GLU 146.A O no hydrogen 3.318 N/A ARG 150.A NE GLU 113.A OE2 no hydrogen 2.962 N/A ARG 150.A NH2 GLU 113.A OE1 no hydrogen 3.111 N/A TRP 151.A N TYR 147.A O no hydrogen 2.771 N/A ASP 152.A N ARG 148.A O no hydrogen 2.792 N/A GLU 153.A N GLN 149.A O no hydrogen 3.222 N/A ALA 154.A N ARG 150.A O no hydrogen 3.168 N/A PHE 155.A N TRP 151.A O no hydrogen 2.815 N/A ARG 156.A N ASP 152.A O no hydrogen 3.039 N/A LYS 157.A N GLU 153.A O no hydrogen 3.058 N/A LYS 157.A NZ GLU 153.A OE2 no hydrogen 2.784 N/A PHE 158.A N ALA 154.A O no hydrogen 3.013 N/A LEU 159.A N PHE 155.A O no hydrogen 2.929 N/A LYS 160.A N ARG 156.A O no hydrogen 2.848 N/A LYS 160.A NZ ALA 209.A O no hydrogen 3.265 N/A GLY 161.A N LYS 157.A O no hydrogen 3.079 N/A LEU 162.A N PHE 158.A O no hydrogen 3.126 N/A ALA 163.A N LEU 159.A O no hydrogen 2.965 N/A SER 164.A N LYS 160.A O no hydrogen 3.188 N/A SER 164.A N GLY 161.A O no hydrogen 3.131 N/A SER 164.A OG GLY 161.A O no hydrogen 2.637 N/A ARG 165.A N LEU 162.A O no hydrogen 2.990 N/A LYS 166.A N LEU 162.A O no hydrogen 3.064 N/A LYS 166.A NZ GLU 124.A OE2 no hydrogen 3.075 N/A LYS 166.A NZ PHE 125.A O no hydrogen 2.761 N/A LYS 166.A NZ ASP 126.A O no hydrogen 3.051 N/A LEU 168.A N SER 251.A OG no hydrogen 2.973 N/A VAL 169.A N VAL 129.A O no hydrogen 2.900 N/A LEU 170.A N LEU 249.A O no hydrogen 2.848 N/A CYS 171.A N VAL 131.A O no hydrogen 2.853 N/A CYS 171.A SG THR 132.A OG1 no hydrogen 3.663 N/A GLY 172.A N TYR 247.A O no hydrogen 3.184 N/A ASP 173.A N ALA 133.A O no hydrogen 3.206 N/A LEU 174.A N LEU 245.A O no hydrogen 2.858 N/A ASN 175.A N ASP 173.A OD1 no hydrogen 2.920 N/A ASN 175.A ND2 VAL 135.A O no hydrogen 2.732 N/A ALA 177.A N GLY 194.A O no hydrogen 2.921 N/A HIS 178.A N TYR 247.A OH no hydrogen 3.140 N/A GLU 179.A N ASP 182.A OD2 no hydrogen 2.803 N/A ASP 182.A N GLU 179.A O no hydrogen 2.828 N/A LEU 183.A N GLU 180.A O no hydrogen 3.283 N/A ARG 184.A N GLY 242.A O no hydrogen 2.951 N/A ARG 184.A NH1 GLY 4.A O no hydrogen 2.968 N/A ARG 184.A NH1 LYS 239.A O no hydrogen 3.013 N/A ARG 184.A NH1 ASN 240.A O no hydrogen 3.147 N/A ARG 184.A NH2 GLY 4.A O no hydrogen 2.591 N/A GLY 188.A N ASN 185.A OD1 no hydrogen 3.360 N/A ASN 189.A N PRO 186.A O no hydrogen 3.229 N/A ASN 189.A ND2 ASN 185.A O no hydrogen 2.891 N/A ASN 192.A N ASN 189.A O no hydrogen 2.882 N/A ASN 192.A ND2 ASN 189.A OD1 no hydrogen 2.907 N/A GLY 194.A N GLU 199.A OE1 no hydrogen 2.880 N/A GLY 194.A N GLU 199.A OE2 no hydrogen 3.197 N/A PHE 195.A N ASN 192.A O no hydrogen 3.115 N/A THR 196.A N GLU 199.A OE1 no hydrogen 3.306 N/A THR 196.A OG1 GLU 199.A OE1 no hydrogen 2.643 N/A GLN 198.A N GLN 198.A OE1 no hydrogen 2.654 N/A GLU 199.A N THR 196.A OG1 no hydrogen 3.146 N/A ARG 200.A N THR 196.A O no hydrogen 3.084 N/A ARG 200.A NE HIS 178.A O no hydrogen 2.884 N/A ARG 200.A NH2 GLU 179.A OE1 no hydrogen 2.893 N/A GLN 201.A N PRO 197.A O no hydrogen 2.852 N/A GLY 202.A N GLN 198.A O no hydrogen 2.947 N/A PHE 203.A N GLU 199.A O no hydrogen 3.080 N/A GLY 204.A N ARG 200.A O no hydrogen 3.063 N/A GLU 205.A N GLN 201.A O no hydrogen 2.887 N/A LEU 206.A N GLY 202.A O no hydrogen 2.966 N/A LEU 207.A N PHE 203.A O no hydrogen 3.086 N/A GLN 208.A N GLY 204.A O no hydrogen 3.219 N/A ALA 209.A N GLU 205.A O no hydrogen 2.806 N/A VAL 210.A N LEU 206.A O no hydrogen 3.371 N/A LEU 212.A N LEU 207.A O no hydrogen 2.736 N/A ALA 213.A N LEU 250.A O no hydrogen 2.761 N/A SER 215.A N PHE 248.A O no hydrogen 3.000 N/A SER 215.A OG PHE 248.A O no hydrogen 2.878 N/A SER 215.A OG SER 261.A OG no hydrogen 2.765 N/A ARG 217.A N ASP 214.A OD1 no hydrogen 3.388 N/A ARG 217.A NH1 TYR 220.A O no hydrogen 2.943 N/A ARG 217.A NH1 THR 223.A O no hydrogen 2.793 N/A ARG 217.A NH2 ASP 182.A OD1 no hydrogen 2.832 N/A HIS 218.A N ASP 214.A O no hydrogen 2.769 N/A LEU 219.A N SER 215.A O no hydrogen 3.258 N/A LEU 219.A N PHE 216.A O no hydrogen 3.134 N/A TYR 220.A N PHE 216.A O no hydrogen 2.856 N/A TYR 220.A OH ASP 260.A OD1 no hydrogen 2.631 N/A THR 223.A N TYR 220.A O no hydrogen 3.370 N/A THR 228.A N TRP 243.A O no hydrogen 2.895 N/A THR 228.A OG1 ASP 246.A OD2 no hydrogen 2.717 N/A PHE 229.A N TRP 243.A O no hydrogen 2.923 N/A TRP 230.A N ASP 271.A O no hydrogen 3.021 N/A TRP 230.A NE1 ASN 240.A OD1 no hydrogen 2.994 N/A THR 231.A OG1.B MET 233.A O no hydrogen 3.268 N/A TYR 232.A OH ASP 33.A OD2 no hydrogen 2.943 N/A ALA 236.A N MET 233.A O no hydrogen 3.302 N/A ARG 237.A NH2 SER 265.A O no hydrogen 2.676 N/A ARG 237.A NH2 ALA 267.A O no hydrogen 2.943 N/A SER 238.A OG ASN 235.A O no hydrogen 2.751 N/A LYS 239.A N ASN 235.A O no hydrogen 3.221 N/A LYS 239.A NZ GLU 3.A O no hydrogen 2.782 N/A ASN 240.A N ARG 237.A O no hydrogen 2.983 N/A ASN 240.A ND2 ALA 6.A O no hydrogen 2.757 N/A ASN 240.A ND2 TYR 225.A O no hydrogen 3.085 N/A VAL 241.A N ALA 236.A O no hydrogen 2.852 N/A TRP 243.A N PHE 229.A O no hydrogen 2.826 N/A ARG 244.A N ASP 182.A O no hydrogen 2.665 N/A ARG 244.A NE ASP 182.A OD1 no hydrogen 2.874 N/A ARG 244.A NH1 ASP 214.A OD1 no hydrogen 3.148 N/A ARG 244.A NH1 ASP 214.A OD2 no hydrogen 3.364 N/A ARG 244.A NH2 ASP 182.A OD1 no hydrogen 2.891 N/A ARG 244.A NH2 ASP 214.A OD2 no hydrogen 2.740 N/A LEU 245.A N THR 228.A OG1 no hydrogen 2.991 N/A ASP 246.A N THR 228.A OG1 no hydrogen 3.119 N/A TYR 247.A N GLY 172.A O no hydrogen 3.077 N/A TYR 247.A OH VAL 176.A O no hydrogen 2.611 N/A LEU 249.A N LEU 170.A O no hydrogen 2.713 N/A LEU 250.A N ALA 213.A O no hydrogen 2.918 N/A SER 251.A N LEU 168.A O no hydrogen 2.995 N/A LEU 254.A N SER 251.A O no hydrogen 2.908 N/A LEU 255.A N HIS 252.A O no hydrogen 3.030 N/A ALA 257.A N LEU 254.A O no hydrogen 2.885 N/A LEU 258.A N LEU 255.A O no hydrogen 2.944 N/A CYS 259.A N TYR 278.A O no hydrogen 3.022 N/A CYS 259.A SG LYS 21.A O no hydrogen 4.038 N/A CYS 259.A SG ALA 257.A O no hydrogen 3.789 N/A ASP 260.A N TYR 278.A O no hydrogen 3.503 N/A SER 261.A N ASP 260.A OD1 no hydrogen 2.837 N/A SER 261.A OG SER 215.A OG no hydrogen 2.765 N/A LYS 262.A N THR 276.A O no hydrogen 2.692 N/A LYS 262.A NZ PRO 11.A O no hydrogen 2.805 N/A LYS 262.A NZ PRO 12.A O no hydrogen 3.133 N/A LYS 262.A NZ ASP 260.A OD2 no hydrogen 2.792 N/A ILE 263.A N ASP 10.A OD2 no hydrogen 2.953 N/A ARG 264.A N PRO 274.A O no hydrogen 2.945 N/A ARG 264.A NE GLU 50.A OE2 no hydrogen 2.915 N/A ARG 264.A NH1 ASP 13.A OD1 no hydrogen 2.867 N/A ARG 264.A NH1 ASP 13.A OD2 no hydrogen 3.517 N/A ARG 264.A NH2 ASP 13.A OD2 no hydrogen 2.965 N/A ARG 264.A NH2 GLU 50.A OE1 no hydrogen 2.943 N/A ARG 264.A NH2 GLU 50.A OE2 no hydrogen 3.563 N/A SER 265.A N ILE 263.A O no hydrogen 3.006 N/A SER 265.A OG ILE 263.A O no hydrogen 3.468 N/A LYS 266.A NZ GLU 9.A OE2 no hydrogen 3.433 N/A ALA 267.A N ARG 264.A O no hydrogen 3.156 N/A SER 270.A OG ASN 31.A O no hydrogen 2.723 N/A SER 270.A OG ASP 271.A OD1 no hydrogen 3.317 N/A HIS 272.A N SER 270.A OG no hydrogen 3.071 N/A HIS 272.A ND1 ASP 246.A OD2 no hydrogen 2.704 N/A CYS 273.A N THR 228.A O no hydrogen 2.874 N/A CYS 273.A SG TYR 227.A O no hydrogen 3.927 N/A CYS 273.A SG PRO 274.A O no hydrogen 3.636 N/A ILE 275.A N SER 29.A O no hydrogen 2.946 N/A THR 276.A N LYS 262.A O no hydrogen 3.033 N/A THR 276.A OG1 GLU 50.A OE2 no hydrogen 2.589 N/A LEU 277.A N ILE 27.A O no hydrogen 2.747 N/A TYR 278.A N ASP 260.A O no hydrogen 3.030 N/A TYR 278.A OH ASP 13.A OD2 no hydrogen 2.729 N/A LEU 279.A N LEU 25.A O no hydrogen 2.871 N/A ALA 280.A N ALA 257.A O no hydrogen 2.713 N/A LEU 281.A N THR 24.A OG1 no hydrogen 2.829 N/A