Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6mzp_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N GLY 183.A O no hydrogen 3.269 N/A VAL 7.A N SER 181.A O no hydrogen 2.844 N/A HIS 11.A N GLY 8.A O no hydrogen 3.228 N/A HIS 11.A NE2 THR 300.A OG1 no hydrogen 2.738 N/A GLN 14.A N ASN 309.A O no hydrogen 2.861 N/A GLN 14.A NE2 GLY 8.A O no hydrogen 2.939 N/A GLN 14.A NE2 HIS 11.A O no hydrogen 3.013 N/A MET 16.A N HIS 307.A O no hydrogen 2.814 N/A LEU 17.A N GLU 177.A O no hydrogen 2.794 N/A LYS 18.A N ASN 306.A OD1 no hydrogen 2.794 N/A SER 19.A N TYR 175.A O no hydrogen 2.969 N/A THR 21.A N ALA 173.A O no hydrogen 3.302 N/A THR 21.A OG1 MET 142.A O no hydrogen 2.806 N/A LEU 23.A N GLU 139.A O no hydrogen 2.822 N/A SER 24.A OG GLU 139.A OE1 no hydrogen 2.705 N/A GLY 25.A N ASP 163.A O no hydrogen 3.125 N/A CYS 26.A N PHE 137.A O no hydrogen 2.997 N/A SER 28.A N THR 135.A O no hydrogen 2.792 N/A SER 28.A OG GLU 158.A O no hydrogen 2.843 N/A ARG 29.A N SER 157.A O no hydrogen 3.051 N/A ARG 29.A NE PHE 156.A O no hydrogen 3.064 N/A GLY 30.A N SER 28.A OG no hydrogen 2.929 N/A THR 31.A OG1 THR 135.A OG1 no hydrogen 2.746 N/A THR 31.A OG1 GLU 152.A OE2 no hydrogen 2.751 N/A THR 32.A N ARG 29.A O no hydrogen 2.982 N/A THR 32.A OG1 ARG 29.A O no hydrogen 2.701 N/A HIS 34.A N THR 31.A O no hydrogen 2.957 N/A HIS 34.A ND1 GLY 30.A O no hydrogen 3.232 N/A GLU 37.A N PRO 65.A O no hydrogen 3.001 N/A VAL 38.A N THR 135.A OG1 no hydrogen 3.082 N/A HIS 39.A N VAL 67.A O no hydrogen 2.724 N/A HIS 39.A ND1 SER 136.A OG no hydrogen 2.745 N/A HIS 39.A NE2 GLU 37.A OE1 no hydrogen 2.798 N/A ILE 40.A N SER 136.A O no hydrogen 2.798 N/A ILE 41.A N ILE 69.A O no hydrogen 2.889 N/A ASN 42.A N SER 138.A O no hydrogen 2.806 N/A ASN 42.A ND2 HIS 118.A O no hydrogen 3.163 N/A ASN 42.A ND2 ASN 120.A OD1 no hydrogen 2.798 N/A LEU 43.A N ASN 71.A O no hydrogen 2.970 N/A ARG 44.A N LEU 140.A O no hydrogen 2.813 N/A ARG 44.A NE GLU 139.A OE2 no hydrogen 2.791 N/A ARG 44.A NH1 HIS 118.A O no hydrogen 2.816 N/A ARG 44.A NH2 HIS 118.A O no hydrogen 2.905 N/A ARG 44.A NH2 GLU 139.A OE2 no hydrogen 3.430 N/A VAL 49.A N LEU 77.A O no hydrogen 3.096 N/A ALA 50.A N HIS 144.A O no hydrogen 3.183 N/A LEU 51.A N LYS 79.A O no hydrogen 2.756 N/A HIS 52.A N ILE 146.A O no hydrogen 2.774 N/A HIS 52.A NE2 ASP 145.A OD2 no hydrogen 2.930 N/A LEU 53.A N ARG 81.A O no hydrogen 2.806 N/A ARG 54.A N ILE 148.A O no hydrogen 3.299 N/A ARG 54.A NH1 GLU 83.A OE1 no hydrogen 2.800 N/A ARG 54.A NH2 GLU 83.A OE1 no hydrogen 3.253 N/A ILE 56.A N VAL 150.A O no hydrogen 2.837 N/A LEU 59.A N ILE 56.A O no hydrogen 3.001 N/A HIS 62.A N LYS 84.A O no hydrogen 2.905 N/A HIS 62.A NE2 GLU 37.A OE2 no hydrogen 2.695 N/A LYS 64.A NZ THR 31.A O no hydrogen 2.723 N/A LYS 64.A NZ HIS 34.A O no hydrogen 2.803 N/A LYS 64.A NZ GLU 152.A OE1 no hydrogen 3.450 N/A LYS 64.A NZ GLU 152.A OE2 no hydrogen 2.808 N/A LEU 66.A N LYS 90.A O no hydrogen 3.130 N/A VAL 67.A N GLU 37.A O no hydrogen 2.763 N/A PHE 68.A N ILE 92.A O no hydrogen 2.805 N/A ILE 69.A N HIS 39.A O no hydrogen 2.951 N/A LEU 70.A N HIS 94.A O no hydrogen 2.771 N/A ASN 71.A N ILE 41.A O no hydrogen 3.031 N/A ASN 71.A ND2 ASN 42.A OD1 no hydrogen 2.801 N/A ASN 71.A ND2 PRO 117.A O no hydrogen 2.884 N/A SER 72.A OG GLN 74.A O no hydrogen 2.931 N/A ILE 76.A N SER 99.A OG no hydrogen 2.877 N/A LEU 77.A N ALA 47.A O no hydrogen 2.815 N/A TRP 78.A N GLU 100.A O no hydrogen 2.766 N/A LYS 79.A N VAL 49.A O no hydrogen 2.889 N/A VAL 80.A N HIS 102.A O no hydrogen 2.763 N/A ARG 81.A N LEU 51.A O no hydrogen 2.930 N/A THR 82.A N GLU 104.A OE1 no hydrogen 3.362 N/A THR 82.A N GLU 104.A OE2 no hydrogen 3.229 N/A GLU 83.A N LEU 53.A O no hydrogen 2.933 N/A ALA 86.A N HIS 62.A O no hydrogen 2.847 N/A LYS 90.A NZ GLU 110.A OE2 no hydrogen 2.907 N/A ARG 91.A N SER 108.A O no hydrogen 3.088 N/A ILE 92.A N LEU 66.A O no hydrogen 2.793 N/A PHE 93.A N GLU 110.A O no hydrogen 2.998 N/A HIS 94.A N PHE 68.A O no hydrogen 2.743 N/A HIS 94.A ND1 GLU 114.A OE2 no hydrogen 2.735 N/A HIS 94.A NE2 TYR 131.A OH no hydrogen 2.755 N/A VAL 95.A N LYS 112.A O no hydrogen 2.952 N/A SER 99.A N VAL 96.A O no hydrogen 3.073 N/A GLU 100.A N ILE 76.A O no hydrogen 3.019 N/A HIS 102.A N TRP 78.A O no hydrogen 2.812 N/A CYS 109.A SG ARG 91.A O no hydrogen 3.590 N/A GLU 110.A N ARG 91.A O no hydrogen 3.361 N/A LYS 112.A N PHE 93.A O no hydrogen 2.727 N/A GLU 114.A N VAL 95.A O no hydrogen 2.861 N/A ASN 120.A ND2 GLU 139.A OE1 no hydrogen 2.866 N/A LEU 123.A N GLY 119.A O no hydrogen 3.067 N/A LEU 124.A N ASN 120.A O no hydrogen 2.957 N/A ASN 125.A N GLU 121.A O no hydrogen 2.957 N/A TRP 126.A N HIS 122.A O no hydrogen 2.851 N/A ALA 127.A N LEU 123.A O no hydrogen 3.054 N/A HIS 128.A N LEU 124.A O no hydrogen 2.877 N/A HIS 129.A N ASN 125.A O no hydrogen 3.079 N/A ARG 130.A N ALA 127.A O no hydrogen 3.017 N/A ARG 130.A NH1 TRP 126.A O no hydrogen 2.976 N/A TYR 131.A N ALA 127.A O no hydrogen 2.800 N/A TYR 131.A OH HIS 94.A NE2 no hydrogen 2.755 N/A THR 135.A N VAL 38.A O no hydrogen 2.774 N/A THR 135.A OG1 THR 31.A OG1 no hydrogen 2.746 N/A SER 136.A N VAL 38.A O no hydrogen 3.181 N/A SER 136.A OG HIS 39.A ND1 no hydrogen 2.745 N/A PHE 137.A N CYS 26.A O no hydrogen 2.909 N/A SER 138.A N ILE 40.A O no hydrogen 2.789 N/A GLU 139.A N SER 24.A O no hydrogen 2.790 N/A LEU 140.A N ASN 42.A O no hydrogen 3.082 N/A ARG 141.A N THR 21.A O no hydrogen 2.783 N/A ILE 146.A N ALA 50.A O no hydrogen 2.915 N/A TYR 147.A N LEU 172.A O no hydrogen 2.730 N/A ILE 148.A N HIS 52.A O no hydrogen 2.798 N/A LYS 149.A N ASN 170.A O no hydrogen 2.734 N/A VAL 150.A N ARG 54.A O no hydrogen 2.797 N/A GLY 151.A N GLU 37.A OE1 no hydrogen 2.789 N/A SER 157.A OG THR 159.A O no hydrogen 3.144 N/A ASP 163.A N GLY 25.A O no hydrogen 2.836 N/A LYS 165.A N ASP 163.A OD1 no hydrogen 3.197 N/A PHE 166.A N ASP 163.A O no hydrogen 3.164 N/A ASN 170.A N SER 168.A OG no hydrogen 3.137 N/A ASN 170.A ND2 ASP 153.A OD2 no hydrogen 3.062 N/A TYR 171.A N SER 168.A O no hydrogen 3.167 N/A LEU 172.A N TYR 147.A O no hydrogen 2.962 N/A SER 174.A N ASP 145.A O no hydrogen 3.492 N/A TYR 175.A N SER 19.A O no hydrogen 3.027 N/A GLU 177.A N LEU 17.A O no hydrogen 2.997 N/A GLN 179.A N ALA 15.A O no hydrogen 2.852 N/A GLN 179.A NE2 GLU 177.A O no hydrogen 3.566 N/A SER 181.A OG THR 302.A OG1 no hydrogen 2.958 N/A THR 182.A N ASN 301.A O no hydrogen 2.947 N/A GLY 183.A N LEU 5.A O no hydrogen 3.095 N/A CYS 184.A N TYR 299.A O no hydrogen 3.060 N/A LEU 186.A N THR 297.A O no hydrogen 2.815 N/A SER 187.A OG VAL 296.A O no hydrogen 2.723 N/A GLU 192.A N ASP 225.A O no hydrogen 2.932 N/A VAL 193.A N THR 297.A OG1 no hydrogen 2.975 N/A HIS 194.A N VAL 227.A O no hydrogen 2.859 N/A HIS 194.A ND1 SER 298.A OG no hydrogen 2.797 N/A HIS 194.A NE2 GLU 192.A OE1 no hydrogen 2.769 N/A ILE 195.A N SER 298.A O no hydrogen 2.946 N/A ILE 196.A N LEU 229.A O no hydrogen 2.841 N/A GLU 197.A N THR 300.A O no hydrogen 2.789 N/A LEU 198.A N LYS 231.A O no hydrogen 2.765 N/A GLN 199.A N THR 302.A O no hydrogen 2.839 N/A GLN 199.A NE2 ASN 301.A OD1 no hydrogen 2.769 N/A ALA 200.A N PRO 303.A O no hydrogen 2.986 N/A ASN 202.A ND2 ALA 204.A O no hydrogen 3.610 N/A GLN 206.A NE2 THR 256.A OG1 no hydrogen 3.130 N/A VAL 209.A N ASN 237.A O no hydrogen 2.857 N/A ILE 210.A N ASN 306.A O no hydrogen 2.943 N/A VAL 211.A N VAL 239.A O no hydrogen 2.771 N/A ASP 212.A N PHE 308.A O no hydrogen 2.807 N/A LEU 213.A N LYS 241.A O no hydrogen 2.872 N/A ARG 214.A N LEU 310.A O no hydrogen 3.171 N/A ARG 214.A NE ASP 212.A OD1 no hydrogen 2.798 N/A ARG 214.A NH2 ASP 212.A OD2 no hydrogen 3.516 N/A LEU 216.A N LEU 312.A O no hydrogen 2.869 N/A ASP 219.A N ASP 217.A OD1 no hydrogen 3.287 N/A LEU 222.A N LYS 244.A O no hydrogen 2.891 N/A ARG 224.A N MET 246.A O no hydrogen 3.029 N/A ARG 224.A NH1 GLU 192.A OE2 no hydrogen 2.662 N/A ARG 224.A NH1 ARG 313.A O no hydrogen 2.795 N/A ARG 224.A NH2 ARG 313.A O no hydrogen 2.868 N/A ASP 225.A N GLU 190.A O no hydrogen 2.851 N/A VAL 226.A N LYS 248.A O no hydrogen 2.785 N/A VAL 227.A N GLU 192.A O no hydrogen 2.876 N/A LEU 228.A N GLU 250.A O no hydrogen 2.836 N/A LEU 229.A N HIS 194.A O no hydrogen 2.918 N/A LEU 230.A N MET 252.A O no hydrogen 2.905 N/A LYS 231.A N ILE 196.A O no hydrogen 2.950 N/A CYS 232.A SG LEU 198.A O no hydrogen 3.417 N/A CYS 232.A SG GLN 199.A O no hydrogen 4.037 N/A CYS 232.A SG LYS 234.A O no hydrogen 3.342 N/A GLU 233.A N LEU 198.A O no hydrogen 3.293 N/A SER 235.A OG GLN 206.A OE1 no hydrogen 3.542 N/A VAL 236.A N ASP 255.A OD1 no hydrogen 3.443 N/A ASN 237.A N VAL 207.A O no hydrogen 3.007 N/A ASN 237.A ND2 ASP 208.A OD1 no hydrogen 2.979 N/A ASN 237.A ND2 SER 258.A OG no hydrogen 2.819 N/A TRP 238.A N THR 256.A O no hydrogen 2.968 N/A TRP 238.A NE1 ASP 255.A OD2 no hydrogen 2.977 N/A VAL 239.A N VAL 209.A O no hydrogen 2.771 N/A ILE 240.A N SER 258.A O no hydrogen 2.814 N/A LYS 241.A N VAL 211.A O no hydrogen 2.883 N/A ALA 242.A N THR 263.A OG1 no hydrogen 2.873 N/A HIS 243.A N LEU 213.A O no hydrogen 2.772 N/A MET 246.A N LEU 222.A O no hydrogen 2.900 N/A LYS 248.A N ASP 225.A OD1 no hydrogen 2.805 N/A LYS 248.A NZ GLU 250.A OE2 no hydrogen 3.367 N/A LEU 249.A N GLN 268.A O no hydrogen 3.054 N/A GLU 250.A N VAL 226.A O no hydrogen 2.937 N/A MET 252.A N LEU 228.A O no hydrogen 2.783 N/A THR 253.A OG1 LEU 230.A O no hydrogen 2.838 N/A ASP 255.A N THR 253.A OG1 no hydrogen 3.266 N/A THR 256.A OG1 ASN 237.A OD1 no hydrogen 2.775 N/A SER 258.A N TRP 238.A O no hydrogen 2.769 N/A SER 260.A N ILE 240.A O no hydrogen 2.987 N/A SER 260.A OG THR 263.A OG1 no hydrogen 2.712 N/A THR 263.A N SER 260.A OG no hydrogen 3.104 N/A THR 263.A OG1 ILE 240.A O no hydrogen 2.945 N/A THR 263.A OG1 SER 260.A OG no hydrogen 2.712 N/A GLU 264.A N SER 260.A O no hydrogen 3.255 N/A ARG 265.A N GLU 261.A O no hydrogen 3.193 N/A LEU 266.A N ASP 262.A O no hydrogen 2.796 N/A MET 267.A N THR 263.A O no hydrogen 2.950 N/A GLN 268.A N GLY 247.A O no hydrogen 2.891 N/A SER 270.A N LEU 249.A O no hydrogen 3.125 N/A LYS 274.A NZ SER 254.A O no hydrogen 2.903 N/A GLN 275.A N THR 253.A O no hydrogen 2.810 N/A GLY 280.A N GLU 197.A OE1 no hydrogen 3.265 N/A GLY 280.A N GLU 197.A OE2 no hydrogen 3.044 N/A LEU 284.A N GLY 280.A O no hydrogen 3.010 N/A ILE 285.A N SER 281.A O no hydrogen 3.034 N/A GLN 286.A N GLN 282.A O no hydrogen 3.261 N/A TRP 287.A N ALA 283.A O no hydrogen 3.000 N/A ALA 288.A N LEU 284.A O no hydrogen 3.058 N/A GLU 289.A N ILE 285.A O no hydrogen 3.110 N/A GLU 290.A N GLN 286.A O no hydrogen 3.015 N/A GLU 290.A N TRP 287.A O no hydrogen 3.267 N/A ASN 291.A N TRP 287.A O no hydrogen 3.083 N/A ASN 291.A ND2 TRP 287.A O no hydrogen 2.813 N/A PHE 293.A N ALA 288.A O no hydrogen 2.966 N/A THR 297.A N VAL 193.A O no hydrogen 2.824 N/A THR 297.A OG1 VAL 193.A O no hydrogen 3.473 N/A SER 298.A N VAL 193.A O no hydrogen 3.423 N/A SER 298.A OG HIS 194.A ND1 no hydrogen 2.797 N/A TYR 299.A N CYS 184.A O no hydrogen 3.032 N/A TYR 299.A OH GLU 197.A OE1 no hydrogen 2.636 N/A THR 300.A N ILE 195.A O no hydrogen 2.779 N/A THR 300.A OG1 HIS 11.A NE2 no hydrogen 2.738 N/A ASN 301.A N THR 182.A O no hydrogen 2.722 N/A ASN 301.A ND2 GLU 197.A OE1 no hydrogen 3.403 N/A ASN 301.A ND2 TYR 299.A OH no hydrogen 2.942 N/A THR 302.A N GLU 197.A O no hydrogen 2.852 N/A THR 302.A OG1 SER 181.A OG no hydrogen 2.958 N/A ALA 305.A N ALA 200.A O no hydrogen 3.286 N/A ASN 306.A N MET 16.A O no hydrogen 3.202 N/A ASN 306.A ND2 LYS 18.A O no hydrogen 2.892 N/A HIS 307.A NE2 ASN 309.A OD1 no hydrogen 2.839 N/A PHE 308.A N ILE 210.A O no hydrogen 2.789 N/A ASN 309.A N GLN 14.A O no hydrogen 2.762 N/A LEU 310.A N ASP 212.A O no hydrogen 2.752 N/A ARG 311.A N PRO 12.A O no hydrogen 2.904 N/A ARG 311.A NH1 ASP 212.A O no hydrogen 3.090 N/A ARG 311.A NH1 ASP 212.A OD1 no hydrogen 3.111 N/A ARG 311.A NH1 LEU 310.A O no hydrogen 2.959 N/A ARG 311.A NH2 ASP 212.A OD1 no hydrogen 3.257 N/A LEU 312.A N ARG 214.A O no hydrogen 3.089 N/A ARG 313.A N GLU 192.A OE2 no hydrogen 3.349 N/A ARG 313.A NH2 ARG 311.A O no hydrogen 3.265 N/A