Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6n1p_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 5.A N LEU 1.A O no hydrogen 2.733 N/A LYS 6.A N THR 2.A O no hydrogen 2.880 N/A ALA 7.A N LYS 3.A O no hydrogen 2.876 N/A SER 8.A N GLU 4.A O no hydrogen 2.899 N/A SER 8.A OG GLU 4.A O no hydrogen 3.554 N/A SER 8.A OG MET 5.A O no hydrogen 2.497 N/A PHE 9.A N MET 5.A O no hydrogen 2.870 N/A ILE 10.A N LYS 6.A O no hydrogen 2.863 N/A ASP 11.A N ALA 7.A O no hydrogen 2.892 N/A TYR 12.A N SER 8.A O no hydrogen 2.860 N/A ALA 13.A N PHE 9.A O no hydrogen 2.916 N/A MET 14.A N ILE 10.A O no hydrogen 2.929 N/A SER 15.A N ASP 11.A O no hydrogen 2.911 N/A SER 15.A OG TYR 12.A O no hydrogen 2.327 N/A VAL 16.A N TYR 12.A O no hydrogen 2.959 N/A ILE 17.A N ALA 13.A O no hydrogen 2.931 N/A VAL 18.A N MET 14.A O no hydrogen 2.890 N/A ALA 19.A N SER 15.A O no hydrogen 2.868 N/A ARG 20.A N VAL 16.A O no hydrogen 2.954 N/A ALA 21.A N ILE 17.A O no hydrogen 2.936 N/A VAL 25.A N ILE 324.A O no hydrogen 2.915 N/A GLY 28.A N ASP 24.A O no hydrogen 2.788 N/A LYS 30.A NZ ALA 21.A O no hydrogen 2.513 N/A ARG 34.A N LYS 30.A O no hydrogen 2.663 N/A ARG 35.A N PRO 31.A O no hydrogen 2.916 N/A ARG 35.A NE PRO 31.A O no hydrogen 3.371 N/A ILE 36.A N VAL 32.A O no hydrogen 2.886 N/A LEU 37.A N HIS 33.A O no hydrogen 2.943 N/A TYR 38.A N ARG 34.A O no hydrogen 2.882 N/A GLY 39.A N ARG 35.A O no hydrogen 2.904 N/A MET 40.A N ILE 36.A O no hydrogen 2.906 N/A ASN 41.A N LEU 37.A O no hydrogen 2.862 N/A GLU 42.A N TYR 38.A O no hydrogen 2.921 N/A GLY 44.A N ASN 41.A O no hydrogen 2.907 N/A LYS 49.A N THR 46.A OG1 no hydrogen 3.309 N/A GLY 59.A N ALA 55.A O no hydrogen 2.844 N/A ASP 60.A N ARG 56.A O no hydrogen 2.952 N/A VAL 61.A N ILE 57.A O no hydrogen 2.921 N/A MET 62.A N THR 58.A O no hydrogen 2.850 N/A GLY 63.A N GLY 59.A O no hydrogen 2.877 N/A LYS 64.A N ASP 60.A O no hydrogen 2.888 N/A LYS 64.A NZ ARG 142.A O no hydrogen 2.559 N/A TYR 65.A N VAL 61.A O no hydrogen 2.926 N/A SER 72.A OG GLY 69.A O no hydrogen 2.292 N/A TYR 74.A N ASP 70.A O no hydrogen 2.922 N/A TYR 74.A OH GLN 108.A O no hydrogen 2.905 N/A GLU 75.A N SER 71.A O no hydrogen 2.825 N/A ALA 76.A N SER 72.A O no hydrogen 2.885 N/A MET 77.A N ILE 73.A O no hydrogen 2.947 N/A VAL 78.A N TYR 74.A O no hydrogen 2.908 N/A ARG 79.A N GLU 75.A O no hydrogen 2.824 N/A MET 80.A N ALA 76.A O no hydrogen 2.985 N/A ALA 81.A N VAL 78.A O no hydrogen 2.806 N/A SER 85.A N GLN 82.A O no hydrogen 3.098 N/A SER 85.A OG GLN 82.A OE1 no hydrogen 3.524 N/A TYR 86.A N GLN 82.A O no hydrogen 2.630 N/A TYR 86.A OH THR 160.A OG1 no hydrogen 2.858 N/A ARG 87.A N ASN 157.A OD1 no hydrogen 2.857 N/A HIS 94.A N GLU 112.A O no hydrogen 2.838 N/A SER 99.A N ASP 103.A OD2 no hydrogen 2.743 N/A SER 99.A OG GLY 98.A O no hydrogen 2.867 N/A THR 111.A OG1 GLN 108.A O no hydrogen 3.225 N/A ALA 113.A N LYS 52.A O no hydrogen 2.829 N/A ARG 114.A N ASP 92.A O no hydrogen 2.913 N/A ARG 114.A NH1 THR 46.A O no hydrogen 2.731 N/A LEU 120.A N SER 116.A O no hydrogen 3.316 N/A LEU 120.A N LYS 117.A O no hydrogen 3.362 N/A MET 122.A N ILE 118.A O no hydrogen 2.890 N/A LEU 123.A N ALA 119.A O no hydrogen 2.942 N/A LYS 128.A N ASP 125.A O no hydrogen 3.366 N/A LYS 128.A NZ ASP 125.A OD1 no hydrogen 2.918 N/A THR 130.A OG1 ASP 125.A O no hydrogen 3.069 N/A VAL 134.A N GLU 143.A O no hydrogen 2.893 N/A ASN 136.A N GLU 141.A O no hydrogen 3.198 N/A ASN 136.A ND2 ASN 140.A OD1 no hydrogen 2.476 N/A ALA 139.A N ASN 136.A O no hydrogen 3.416 N/A ASN 140.A N ASN 136.A OD1 no hydrogen 3.120 N/A GLU 143.A N VAL 134.A O no hydrogen 2.903 N/A LEU 147.A N ASP 27.A OD1 no hydrogen 3.341 N/A ARG 150.A NH1 ALA 149.A O no hydrogen 2.289 N/A ASN 153.A N PHE 151.A O no hydrogen 3.039 N/A LEU 155.A N PRO 152.A O no hydrogen 2.978 N/A ASN 157.A N ASN 153.A O no hydrogen 2.869 N/A ALA 159.A N ILE 170.A O no hydrogen 2.911 N/A THR 160.A OG1 TYR 86.A OH no hydrogen 2.858 N/A THR 160.A OG1 THR 160.A O no hydrogen 2.626 N/A GLY 161.A N THR 168.A O no hydrogen 2.916 N/A VAL 164.A N ILE 162.A O no hydrogen 3.060 N/A THR 168.A OG1 ALA 167.A O no hydrogen 2.838 N/A ASN 169.A ND2 GLY 318.A O no hydrogen 2.937 N/A ILE 170.A N ALA 159.A O no hydrogen 2.893 N/A ASN 174.A ND2 ASP 468.A O no hydrogen 2.903 N/A LEU 175.A N TYR 88.A OH no hydrogen 3.180 N/A THR 178.A N ASN 174.A O no hydrogen 3.070 N/A THR 178.A OG1 ASN 174.A O no hydrogen 2.455 N/A ILE 179.A N LEU 175.A O no hydrogen 2.975 N/A ASP 180.A N GLY 176.A O no hydrogen 2.875 N/A ALA 181.A N GLU 177.A O no hydrogen 2.925 N/A VAL 182.A N THR 178.A O no hydrogen 2.897 N/A LYS 183.A N ILE 179.A O no hydrogen 2.915 N/A LEU 184.A N ASP 180.A O no hydrogen 2.851 N/A VAL 185.A N ALA 181.A O no hydrogen 2.951 N/A MET 186.A N VAL 182.A O no hydrogen 2.875 N/A ASP 187.A N LYS 183.A O no hydrogen 2.897 N/A ASN 188.A N LEU 184.A O no hydrogen 2.887 N/A THR 192.A N ASP 195.A OD2 no hydrogen 2.399 N/A THR 192.A OG1 ASP 195.A OD2 no hydrogen 2.937 N/A THR 193.A OG1 GLU 222.A OE2 no hydrogen 3.446 N/A ASP 195.A N THR 192.A OG1 no hydrogen 3.315 N/A LEU 196.A N THR 192.A O no hydrogen 3.370 N/A MET 197.A N THR 193.A O no hydrogen 2.888 N/A GLU 198.A N LYS 194.A O no hydrogen 2.932 N/A VAL 199.A N ASP 195.A O no hydrogen 3.046 N/A LEU 200.A N LEU 196.A O no hydrogen 2.788 N/A ASP 204.A N PRO 172.A O no hydrogen 3.016 N/A PHE 205.A N THR 472.A OG1 no hydrogen 2.647 N/A HIS 218.A N LYS 214.A O no hydrogen 2.940 N/A LYS 219.A N SER 215.A O no hydrogen 2.858 N/A ALA 220.A N GLY 216.A O no hydrogen 2.859 N/A TYR 221.A N ILE 217.A O no hydrogen 2.951 N/A GLU 222.A N HIS 218.A O no hydrogen 2.992 N/A THR 223.A N LYS 219.A O no hydrogen 2.828 N/A THR 223.A OG1 LYS 219.A O no hydrogen 2.312 N/A GLY 224.A N LYS 219.A O no hydrogen 3.245 N/A GLY 224.A N ALA 220.A O no hydrogen 3.160 N/A LYS 225.A N THR 223.A OG1 no hydrogen 3.046 N/A LYS 225.A NZ ASN 320.A O no hydrogen 2.702 N/A SER 227.A OG ILE 228.A O no hydrogen 3.443 N/A ILE 228.A N PHE 317.A O no hydrogen 2.863 N/A LEU 230.A N THR 315.A O no hydrogen 2.915 N/A ARG 231.A N LEU 210.A O no hydrogen 2.933 N/A SER 232.A N MET 313.A O no hydrogen 2.825 N/A SER 232.A OG GLU 250.A O no hydrogen 3.425 N/A ARG 233.A N GLU 250.A O no hydrogen 3.348 N/A ARG 233.A NH2 GLU 250.A OE2 no hydrogen 3.142 N/A ARG 233.A NH2 GLU 473.A O no hydrogen 2.818 N/A GLU 235.A N VAL 247.A O no hydrogen 2.904 N/A GLU 237.A N ARG 245.A O no hydrogen 2.896 N/A THR 239.A N ARG 243.A O no hydrogen 3.067 N/A THR 239.A OG1 ARG 243.A O no hydrogen 2.903 N/A GLY 242.A N THR 239.A O no hydrogen 2.939 N/A ARG 243.A NH2 GLU 293.A O no hydrogen 2.456 N/A ARG 245.A N GLU 237.A O no hydrogen 2.895 N/A ARG 245.A NE GLU 293.A OE2 no hydrogen 2.672 N/A ARG 245.A NH1 THR 238.A O no hydrogen 3.405 N/A ARG 245.A NH2 GLU 293.A OE2 no hydrogen 2.968 N/A ILE 246.A N ILE 292.A O no hydrogen 2.884 N/A VAL 247.A N GLU 235.A O no hydrogen 2.872 N/A VAL 248.A N PHE 290.A O no hydrogen 2.844 N/A PHE 251.A N GLY 208.A O no hydrogen 3.277 N/A TYR 253.A OH SER 85.A O no hydrogen 2.400 N/A ASN 256.A ND2 ASP 101.A O no hydrogen 2.662 N/A HIS 261.A N LYS 257.A O no hydrogen 2.928 N/A GLU 262.A N THR 258.A O no hydrogen 2.945 N/A HIS 263.A N LYS 259.A O no hydrogen 2.923 N/A ILE 264.A N VAL 260.A O no hydrogen 2.908 N/A VAL 265.A N HIS 261.A O no hydrogen 2.931 N/A ARG 266.A N GLU 262.A O no hydrogen 2.903 N/A LEU 267.A N HIS 263.A O no hydrogen 2.874 N/A VAL 268.A N ILE 264.A O no hydrogen 2.933 N/A GLN 269.A N VAL 265.A O no hydrogen 2.942 N/A GLU 274.A N GLU 274.A OE1 no hydrogen 2.733 N/A ARG 280.A N VAL 291.A O no hydrogen 2.658 N/A SER 283.A OG SER 283.A O no hydrogen 2.522 N/A SER 283.A OG GLU 286.A OE2 no hydrogen 3.533 N/A ARG 289.A N ASN 284.A OD1 no hydrogen 2.464 N/A PHE 290.A N VAL 248.A O no hydrogen 2.950 N/A VAL 291.A N ARG 280.A O no hydrogen 2.954 N/A ILE 292.A N ILE 246.A O no hydrogen 2.931 N/A GLU 293.A N ALA 278.A O no hydrogen 3.292 N/A LYS 295.A NZ ARG 296.A O no hydrogen 2.430 N/A ALA 300.A N GLU 244.A OE1 no hydrogen 2.535 N/A LEU 304.A N ALA 300.A O no hydrogen 2.895 N/A ASN 305.A N ASN 301.A O no hydrogen 2.888 N/A ASN 306.A N VAL 302.A O no hydrogen 2.900 N/A LEU 307.A N ILE 303.A O no hydrogen 2.897 N/A PHE 308.A N LEU 304.A O no hydrogen 2.880 N/A LYS 309.A N ASN 305.A O no hydrogen 2.879 N/A MET 310.A N ASN 306.A O no hydrogen 2.906 N/A THR 311.A N PHE 308.A O no hydrogen 3.021 N/A THR 311.A OG1 MET 310.A O no hydrogen 2.647 N/A THR 315.A N LEU 230.A O no hydrogen 2.875 N/A THR 315.A OG1 THR 311.A O no hydrogen 2.705 N/A PHE 317.A N ILE 228.A O no hydrogen 2.871 N/A ASN 320.A ND2 ALA 167.A O no hydrogen 2.762 N/A ALA 323.A N LYS 330.A O no hydrogen 2.930 N/A GLN 325.A N ILE 328.A O no hydrogen 2.900 N/A ILE 328.A N GLN 325.A O no hydrogen 2.904 N/A LEU 332.A N MET 321.A O no hydrogen 3.257 N/A SER 333.A N GLN 336.A OE1 no hydrogen 2.821 N/A SER 333.A OG LEU 334.A O no hydrogen 3.208 N/A ALA 340.A N GLN 336.A O no hydrogen 2.948 N/A TYR 341.A N ILE 337.A O no hydrogen 2.925 N/A ILE 342.A N LEU 338.A O no hydrogen 2.926 N/A GLU 343.A N ASP 339.A O no hydrogen 2.911 N/A HIS 344.A N ALA 340.A O no hydrogen 2.933 N/A GLN 345.A N TYR 341.A O no hydrogen 2.947 N/A GLN 345.A NE2 ALA 149.A O no hydrogen 2.584 N/A LYS 346.A N ILE 342.A O no hydrogen 2.896 N/A GLU 347.A N GLU 343.A O no hydrogen 2.933 N/A VAL 348.A N HIS 344.A O no hydrogen 2.969 N/A VAL 349.A N GLN 345.A O no hydrogen 2.913 N/A VAL 350.A N LYS 346.A O no hydrogen 2.955 N/A ARG 351.A N GLU 347.A O no hydrogen 2.953 N/A ARG 352.A N VAL 348.A O no hydrogen 2.920 N/A ARG 352.A NH1 ASP 125.A OD2 no hydrogen 3.456 N/A ARG 352.A NH1 GLU 458.A OE2 no hydrogen 3.381 N/A THR 353.A N VAL 349.A O no hydrogen 2.859 N/A THR 353.A OG1 VAL 349.A O no hydrogen 2.696 N/A ARG 354.A N VAL 350.A O no hydrogen 2.914 N/A PHE 355.A N ARG 351.A O no hydrogen 2.973 N/A ASP 356.A N ARG 352.A O no hydrogen 2.916 N/A LYS 357.A N THR 353.A O no hydrogen 2.914 N/A GLU 358.A N ARG 354.A O no hydrogen 2.941 N/A LYS 359.A N PHE 355.A O no hydrogen 3.032 N/A ALA 360.A N ASP 356.A O no hydrogen 2.889 N/A GLU 361.A N LYS 357.A O no hydrogen 2.854 N/A ALA 362.A N GLU 358.A O no hydrogen 2.993 N/A ARG 363.A N LYS 359.A O no hydrogen 2.969 N/A ALA 364.A N ALA 360.A O no hydrogen 2.816 N/A HIS 365.A N GLU 361.A O no hydrogen 2.925 N/A HIS 365.A NE2 SER 404.A OG no hydrogen 2.504 N/A ILE 366.A N ALA 362.A O no hydrogen 3.029 N/A LEU 367.A N ARG 363.A O no hydrogen 2.913 N/A GLU 368.A N ALA 364.A O no hydrogen 2.831 N/A GLY 369.A N HIS 365.A O no hydrogen 3.081 N/A LEU 370.A N ILE 366.A O no hydrogen 2.869 N/A LEU 371.A N LEU 367.A O no hydrogen 2.910 N/A ILE 372.A N GLU 368.A O no hydrogen 2.996 N/A ALA 373.A N GLY 369.A O no hydrogen 2.927 N/A LEU 374.A N LEU 370.A O no hydrogen 2.915 N/A ILE 381.A N ILE 377.A O no hydrogen 2.922 N/A ARG 382.A N ASP 378.A O no hydrogen 2.909 N/A ILE 383.A N GLU 379.A O no hydrogen 2.957 N/A ILE 384.A N VAL 380.A O no hydrogen 2.902 N/A ARG 385.A N ILE 381.A O no hydrogen 2.913 N/A ALA 386.A N ARG 382.A O no hydrogen 3.157 N/A ALA 386.A N ILE 383.A O no hydrogen 3.012 N/A SER 387.A N ILE 384.A O no hydrogen 2.865 N/A SER 387.A OG ILE 384.A O no hydrogen 2.611 N/A SER 387.A OG GLU 396.A OE1 no hydrogen 3.456 N/A GLU 388.A N GLU 392.A OE1 no hydrogen 2.852 N/A ALA 393.A N THR 389.A O no hydrogen 2.681 N/A GLN 394.A N ASP 390.A O no hydrogen 2.854 N/A ALA 395.A N ALA 391.A O no hydrogen 2.948 N/A GLU 396.A N GLU 392.A O no hydrogen 2.842 N/A LEU 397.A N ALA 393.A O no hydrogen 2.894 N/A MET 398.A N GLN 394.A O no hydrogen 2.920 N/A SER 399.A N ALA 395.A O no hydrogen 2.937 N/A SER 399.A OG ALA 395.A O no hydrogen 3.530 N/A SER 399.A OG GLU 396.A O no hydrogen 2.325 N/A LYS 400.A N GLU 396.A O no hydrogen 2.851 N/A LYS 400.A NZ VAL 380.A O no hydrogen 3.297 N/A PHE 401.A N LEU 397.A O no hydrogen 2.923 N/A SER 404.A N GLN 407.A OE1 no hydrogen 3.069 N/A SER 404.A OG HIS 365.A NE2 no hydrogen 2.504 N/A GLN 407.A NE2 HIS 365.A O no hydrogen 2.426 N/A SER 408.A N SER 404.A O no hydrogen 2.700 N/A SER 408.A OG SER 404.A O no hydrogen 3.181 N/A SER 408.A OG GLU 405.A O no hydrogen 2.553 N/A GLN 409.A N GLU 405.A O no hydrogen 2.949 N/A ALA 410.A N ARG 406.A O no hydrogen 2.881 N/A ILE 411.A N GLN 407.A O no hydrogen 2.928 N/A LEU 412.A N SER 408.A O no hydrogen 2.899 N/A ASP 413.A N GLN 409.A O no hydrogen 2.920 N/A ARG 418.A N ARG 415.A O no hydrogen 3.165 N/A LEU 419.A N LEU 416.A O no hydrogen 2.976 N/A ASP 425.A N GLY 421.A O no hydrogen 3.474 N/A LYS 426.A N LEU 422.A O no hydrogen 2.988 N/A LYS 426.A NZ GLU 423.A OE1 no hydrogen 3.477 N/A LYS 426.A NZ GLU 423.A OE2 no hydrogen 3.179 N/A ILE 427.A N GLU 423.A O no hydrogen 2.893 N/A GLN 428.A N ARG 424.A O no hydrogen 2.923 N/A SER 429.A N ASP 425.A O no hydrogen 2.862 N/A SER 429.A OG ASP 425.A O no hydrogen 3.346 N/A SER 429.A OG LYS 426.A O no hydrogen 2.512 N/A GLU 430.A N LYS 426.A O no hydrogen 2.983 N/A TYR 431.A N ILE 427.A O no hydrogen 2.818 N/A ASP 432.A N GLN 428.A O no hydrogen 2.920 N/A ASP 433.A N SER 429.A O no hydrogen 2.922 N/A LEU 434.A N GLU 430.A O no hydrogen 2.819 N/A LEU 435.A N TYR 431.A O no hydrogen 2.903 N/A ALA 436.A N ASP 432.A O no hydrogen 2.902 N/A LEU 437.A N ASP 433.A O no hydrogen 2.920 N/A ILE 438.A N LEU 434.A O no hydrogen 2.874 N/A ALA 439.A N LEU 435.A O no hydrogen 2.933 N/A ASP 440.A N ALA 436.A O no hydrogen 2.877 N/A LEU 441.A N LEU 437.A O no hydrogen 2.910 N/A ALA 442.A N ILE 438.A O no hydrogen 2.894 N/A ASP 443.A N ALA 439.A O no hydrogen 2.924 N/A ILE 444.A N ASP 440.A O no hydrogen 2.859 N/A LEU 445.A N LEU 441.A O no hydrogen 2.896 N/A ALA 446.A N ALA 442.A O no hydrogen 2.937 N/A ARG 450.A NH1 ARG 450.A O no hydrogen 3.184 N/A SER 452.A OG GLU 449.A O no hydrogen 2.314 N/A GLN 453.A N GLU 449.A O no hydrogen 2.927 N/A ILE 454.A N ARG 450.A O no hydrogen 2.914 N/A ILE 455.A N VAL 451.A O no hydrogen 2.957 N/A LYS 456.A N SER 452.A O no hydrogen 2.871 N/A ASP 457.A N GLN 453.A O no hydrogen 2.850 N/A GLU 458.A N ILE 454.A O no hydrogen 2.994 N/A LEU 459.A N ILE 455.A O no hydrogen 2.911 N/A ASP 460.A N LYS 456.A O no hydrogen 2.867 N/A GLU 461.A N ASP 457.A O no hydrogen 2.869 N/A VAL 462.A N GLU 458.A O no hydrogen 2.991 N/A LYS 463.A N LEU 459.A O no hydrogen 2.859 N/A LYS 463.A NZ SER 467.A OG no hydrogen 3.306 N/A ARG 464.A N ASP 460.A O no hydrogen 2.862 N/A LYS 465.A N GLU 461.A O no hydrogen 2.942 N/A LYS 465.A NZ GLU 121.A OE2 no hydrogen 1.891 N/A PHE 466.A N VAL 462.A O no hydrogen 2.769 N/A SER 467.A OG LYS 463.A O no hydrogen 3.343 N/A SER 467.A OG PHE 466.A O no hydrogen 2.757 N/A ARG 470.A NH1 GLU 177.A OE2 no hydrogen 2.987 N/A ARG 470.A NH1 GLY 202.A O no hydrogen 2.610 N/A ARG 470.A NH2 GLY 202.A O no hydrogen 2.928 N/A