Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6nk5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 1.A N ILE 282.A O no hydrogen 3.170 N/A TYR 1.A N ASP 284.A OD1 no hydrogen 3.224 N/A HIS 3.A N ILE 280.A O no hydrogen 2.878 N/A THR 5.A N ILE 278.A O no hydrogen 2.945 N/A THR 5.A OG1 ILE 278.A O no hydrogen 3.318 N/A ILE 7.A N ILE 276.A O no hydrogen 2.919 N/A ASN 9.A N GLY 274.A O no hydrogen 2.878 N/A ASN 9.A ND2 CYS 271.A O no hydrogen 2.901 N/A ASN 9.A ND2 VAL 273.A O no hydrogen 2.913 N/A THR 10.A OG1 VAL 11.A O no hydrogen 3.527 N/A GLY 12.A N LEU 33.A O no hydrogen 3.468 N/A TYR 15.A N MET 31.A O no hydrogen 2.887 N/A TYR 15.A OH SER 393.A OG no hydrogen 2.278 N/A THR 17.A N LEU 29.A O no hydrogen 2.881 N/A VAL 19.A N MET 27.A O no hydrogen 2.896 N/A ARG 21.A NH1 ASP 284.A OD2 no hydrogen 2.431 N/A TYR 24.A N ARG 21.A O no hydrogen 3.464 N/A SER 25.A N THR 288.A O no hydrogen 2.889 N/A SER 25.A OG THR 288.A O no hydrogen 2.527 N/A SER 25.A OG THR 288.A OG1 no hydrogen 2.348 N/A MET 27.A N VAL 19.A O no hydrogen 2.939 N/A LEU 29.A N THR 17.A O no hydrogen 2.904 N/A MET 31.A N TYR 15.A O no hydrogen 2.903 N/A GLU 32.A N ARG 134.A O no hydrogen 2.962 N/A GLN 34.A N LYS 132.A O no hydrogen 2.911 N/A GLN 34.A NE2 GLU 32.A O no hydrogen 2.417 N/A SER 35.A N LYS 132.A O no hydrogen 3.340 N/A THR 37.A N SER 130.A O no hydrogen 2.558 N/A LEU 38.A N ALA 268.A O no hydrogen 2.808 N/A THR 41.A N HIS 125.A O no hydrogen 3.180 N/A THR 41.A OG1 HIS 125.A O no hydrogen 2.754 N/A SER 43.A OG ARG 123.A O no hydrogen 2.390 N/A TYR 46.A N ALA 121.A O no hydrogen 3.007 N/A TYR 46.A OH PRO 190.A O no hydrogen 2.605 N/A THR 48.A N ALA 119.A O no hydrogen 2.894 N/A THR 48.A OG1 ILE 203.A O no hydrogen 3.224 N/A CYS 49.A SG GLU 50.A O no hydrogen 3.317 N/A CYS 49.A SG SER 113.A OG no hydrogen 3.539 N/A CYS 49.A SG GLU 117.A O no hydrogen 3.787 N/A TYR 51.A N GLU 50.A OE2 no hydrogen 2.765 N/A TYR 51.A OH ALA 236.A O no hydrogen 2.428 N/A LYS 52.A N GLU 109.A O no hydrogen 2.907 N/A LYS 52.A NZ LYS 110.A O no hydrogen 3.485 N/A VAL 54.A N HIS 107.A O no hydrogen 2.893 N/A TYR 59.A N LEU 103.A O no hydrogen 2.944 N/A LYS 61.A N THR 101.A O no hydrogen 2.888 N/A LYS 61.A NZ TYR 59.A OH no hydrogen 3.502 N/A LEU 73.A N LYS 71.A O no hydrogen 2.764 N/A SER 77.A N GLU 105.A OE2 no hydrogen 3.368 N/A SER 77.A N ALA 106.A O no hydrogen 3.015 N/A SER 77.A OG ASP 75.A O no hydrogen 3.340 N/A SER 77.A OG LEU 219.A O no hydrogen 3.167 N/A LYS 79.A N SER 104.A O no hydrogen 2.911 N/A LYS 79.A NZ VAL 80.A O no hydrogen 2.355 N/A PHE 81.A N GLN 102.A O no hydrogen 2.853 N/A MET 88.A N GLY 91.A O no hydrogen 2.736 N/A CYS 96.A SG ASN 100.A OD1 no hydrogen 3.283 N/A ASN 100.A N ASP 97.A O no hydrogen 3.347 N/A ASN 100.A ND2 CYS 96.A O no hydrogen 2.541 N/A THR 101.A N LYS 61.A O no hydrogen 2.890 N/A THR 101.A OG1 LYS 61.A O no hydrogen 2.468 N/A THR 101.A OG1 GLY 64.A O no hydrogen 2.797 N/A GLN 102.A N PHE 81.A O no hydrogen 2.878 N/A GLN 102.A NE2 HIS 230.A O no hydrogen 3.167 N/A LEU 103.A N TYR 59.A O no hydrogen 2.856 N/A SER 104.A N LYS 79.A O no hydrogen 2.871 N/A SER 104.A OG LYS 79.A O no hydrogen 2.577 N/A ALA 106.A N SER 77.A O no hydrogen 2.837 N/A HIS 107.A N VAL 54.A O no hydrogen 3.035 N/A VAL 108.A N PRO 74.A O no hydrogen 3.080 N/A GLU 109.A N LYS 52.A O no hydrogen 2.878 N/A SER 111.A OG GLU 50.A O no hydrogen 2.371 N/A SER 111.A OG TYR 51.A O no hydrogen 2.585 N/A GLU 112.A N GLU 112.A OE2 no hydrogen 2.995 N/A SER 113.A OG GLU 117.A OE1 no hydrogen 2.694 N/A CYS 114.A SG GLU 50.A O no hydrogen 3.381 N/A CYS 114.A SG SER 111.A O no hydrogen 3.802 N/A LYS 115.A NZ SER 111.A O no hydrogen 3.166 N/A THR 116.A N SER 113.A O no hydrogen 3.313 N/A GLU 117.A N SER 113.A O no hydrogen 2.768 N/A ALA 119.A N THR 48.A O no hydrogen 2.980 N/A SER 120.A N VAL 179.A O no hydrogen 2.966 N/A SER 120.A OG VAL 179.A O no hydrogen 3.383 N/A ALA 121.A N TYR 46.A O no hydrogen 2.920 N/A ARG 123.A N SER 43.A O no hydrogen 2.969 N/A ARG 123.A NH1 ALA 124.A O no hydrogen 2.835 N/A HIS 125.A N THR 41.A OG1 no hydrogen 2.514 N/A SER 128.A N GLU 39.A O no hydrogen 3.002 N/A SER 128.A OG GLU 39.A O no hydrogen 3.363 N/A SER 130.A N THR 37.A O no hydrogen 2.715 N/A ALA 131.A N ALA 146.A O no hydrogen 2.873 N/A LYS 132.A N SER 35.A O no hydrogen 2.681 N/A LYS 132.A NZ GLN 34.A OE1 no hydrogen 2.398 N/A LEU 133.A N VAL 144.A O no hydrogen 2.849 N/A ARG 134.A N GLU 32.A O no hydrogen 2.857 N/A ARG 134.A NH1 ASN 141.A OD1 no hydrogen 2.620 N/A VAL 135.A N ILE 142.A O no hydrogen 2.940 N/A TYR 137.A N ASN 140.A O no hydrogen 2.856 N/A ASN 140.A N TYR 137.A O no hydrogen 2.968 N/A ASN 140.A ND2 TYR 137.A O no hydrogen 2.385 N/A ILE 142.A N VAL 135.A O no hydrogen 2.864 N/A VAL 144.A N LEU 133.A O no hydrogen 2.923 N/A ALA 146.A N ALA 131.A O no hydrogen 2.930 N/A ALA 148.A N ALA 129.A O no hydrogen 2.471 N/A GLY 150.A N ASN 149.A OD1 no hydrogen 2.494 N/A ASP 151.A N ASN 149.A OD1 no hydrogen 2.528 N/A HIS 152.A N ASN 149.A OD1 no hydrogen 2.591 N/A VAL 154.A N PHE 161.A O no hydrogen 2.914 N/A VAL 156.A N ALA 159.A O no hydrogen 2.907 N/A LYS 157.A NZ ASN 140.A OD1 no hydrogen 2.870 N/A LYS 160.A N ASP 281.A O no hydrogen 2.895 N/A PHE 161.A N VAL 154.A O no hydrogen 2.991 N/A VAL 162.A N SER 279.A O no hydrogen 2.951 N/A GLY 164.A N PRO 277.A O no hydrogen 3.146 N/A SER 167.A OG ASN 275.A O no hydrogen 3.012 N/A SER 167.A OG ASN 275.A OD1 no hydrogen 2.480 N/A SER 168.A OG VAL 273.A O no hydrogen 2.918 N/A LYS 176.A NZ TYR 189.A O no hydrogen 2.916 N/A ILE 177.A N TYR 122.A O no hydrogen 2.990 N/A VAL 178.A N TYR 185.A O no hydrogen 3.043 N/A VAL 179.A N SER 120.A O no hydrogen 2.956 N/A TYR 180.A N ASP 183.A O no hydrogen 2.946 N/A GLY 182.A N TYR 180.A O no hydrogen 2.464 N/A ASP 183.A N TYR 180.A O no hydrogen 3.045 N/A TYR 185.A N VAL 178.A O no hydrogen 2.850 N/A TYR 189.A OH ASP 45.A OD2 no hydrogen 2.388 N/A TYR 189.A OH TYR 122.A O no hydrogen 3.168 N/A GLY 193.A N GLN 204.A OE1 no hydrogen 2.574 N/A ASP 202.A N GLN 199.A O no hydrogen 2.802 N/A ILE 203.A N ASP 202.A OD1 no hydrogen 2.687 N/A GLN 204.A N TYR 214.A O no hydrogen 2.860 N/A GLN 204.A NE2 PRO 191.A O no hydrogen 3.242 N/A SER 205.A OG THR 207.A O no hydrogen 2.453 N/A THR 207.A N SER 210.A OG no hydrogen 2.864 N/A THR 207.A OG1 SER 210.A OG no hydrogen 2.509 N/A GLU 209.A N THR 207.A OG1 no hydrogen 2.870 N/A SER 210.A OG THR 207.A OG1 no hydrogen 2.509 N/A TYR 214.A N GLN 204.A O no hydrogen 2.978 N/A ASN 216.A N ASP 202.A O no hydrogen 2.798 N/A ASN 216.A ND2 GLY 195.A O no hydrogen 2.470 N/A THR 217.A N ASP 75.A OD2 no hydrogen 3.290 N/A THR 217.A OG1 ASP 75.A OD2 no hydrogen 2.591 N/A GLN 218.A NE2 ASN 216.A OD1 no hydrogen 3.061 N/A VAL 220.A N SER 234.A OG no hydrogen 2.707 N/A GLN 222.A N PRO 232.A O no hydrogen 2.450 N/A ARG 223.A NH1 THR 82.A O no hydrogen 3.038 N/A ARG 223.A NH2 THR 82.A O no hydrogen 2.467 N/A ALA 225.A N THR 228.A OG1 no hydrogen 2.628 N/A GLY 227.A N TYR 85.A O no hydrogen 2.445 N/A THR 228.A N ALA 225.A O no hydrogen 3.153 N/A THR 228.A OG1 ALA 225.A O no hydrogen 2.864 N/A THR 228.A OG1 THR 228.A O no hydrogen 2.386 N/A VAL 229.A N GLY 227.A O no hydrogen 2.694 N/A SER 234.A N VAL 220.A O no hydrogen 2.392 N/A SER 238.A OG GLU 50.A OE1 no hydrogen 2.543 N/A LYS 241.A N SER 238.A OG no hydrogen 3.077 N/A TYR 242.A OH GLY 198.A O no hydrogen 2.411 N/A TRP 243.A N GLY 239.A O no hydrogen 2.968 N/A LEU 244.A N PHE 240.A O no hydrogen 2.523 N/A LYS 245.A N TYR 242.A O no hydrogen 2.866 N/A GLU 246.A N TYR 242.A O no hydrogen 2.775 N/A ARG 247.A NH1 ASP 183.A OD2 no hydrogen 2.705 N/A LEU 251.A N VAL 184.A O no hydrogen 3.372 N/A GLN 252.A N SER 250.A OG no hydrogen 2.961 N/A HIS 253.A N SER 250.A O no hydrogen 3.285 N/A THR 254.A OG1 THR 254.A O no hydrogen 2.409 N/A CYS 259.A N PRO 256.A O no hydrogen 3.441 N/A CYS 259.A SG PRO 256.A O no hydrogen 3.358 N/A GLN 260.A N VAL 269.A O no hydrogen 2.920 N/A ILE 261.A N GLN 252.A OE1 no hydrogen 2.776 N/A ALA 262.A N ARG 267.A O no hydrogen 2.944 N/A ARG 267.A NH1 THR 263.A O no hydrogen 2.387 N/A ARG 267.A NH1 PRO 265.A O no hydrogen 2.572 N/A ALA 268.A N LEU 38.A O no hydrogen 2.704 N/A VAL 269.A N GLN 260.A O no hydrogen 2.883 N/A ASN 270.A N VAL 36.A O no hydrogen 3.025 N/A ILE 276.A N ILE 7.A O no hydrogen 2.911 N/A ILE 278.A N THR 5.A O no hydrogen 2.867 N/A SER 279.A N VAL 162.A O no hydrogen 2.951 N/A ILE 280.A N HIS 3.A O no hydrogen 2.902 N/A ASP 281.A N LYS 160.A O no hydrogen 2.855 N/A ILE 282.A N TYR 1.A O no hydrogen 3.383 N/A ALA 286.A N PRO 283.A O no hydrogen 3.489 N/A THR 288.A OG1 SER 25.A OG no hydrogen 2.348 N/A ASP 292.A N ARG 289.A O no hydrogen 3.227 N/A ALA 293.A N VAL 290.A O no hydrogen 3.191 N/A SER 295.A OG VAL 296.A O no hydrogen 3.514 N/A THR 297.A N THR 321.A O no hydrogen 3.155 N/A SER 300.A N LYS 319.A O no hydrogen 2.962 N/A GLU 302.A N ILE 317.A O no hydrogen 2.967 N/A THR 307.A N GLY 313.A O no hydrogen 2.645 N/A HIS 308.A N HIS 381.A O no hydrogen 2.973 N/A SER 309.A N THR 307.A O no hydrogen 2.668 N/A ASP 311.A N SER 309.A OG no hydrogen 3.378 N/A PHE 312.A N ASP 311.A OD1 no hydrogen 2.600 N/A GLY 313.A N SER 357.A OG no hydrogen 2.556 N/A GLY 314.A N PHE 356.A O no hydrogen 2.890 N/A VAL 315.A N ALA 305.A O no hydrogen 3.000 N/A ALA 316.A N ILE 354.A O no hydrogen 2.912 N/A ILE 317.A N GLU 302.A O no hydrogen 2.909 N/A ILE 318.A N LEU 352.A O no hydrogen 2.863 N/A LYS 319.A N SER 300.A O no hydrogen 2.862 N/A LYS 319.A NZ TYR 320.A O no hydrogen 2.765 N/A LYS 319.A NZ ASN 349.A OD1 no hydrogen 2.730 N/A LYS 319.A NZ SER 350.A O no hydrogen 2.596 N/A TYR 320.A N SER 350.A O no hydrogen 2.933 N/A THR 321.A OG1 THR 297.A O no hydrogen 2.357 N/A THR 321.A OG1 THR 321.A O no hydrogen 2.520 N/A ALA 322.A N GLY 348.A O no hydrogen 2.424 N/A SER 323.A N SER 295.A O no hydrogen 3.113 N/A SER 323.A OG SER 295.A O no hydrogen 2.996 N/A LYS 325.A NZ GLU 345.A OE2 no hydrogen 2.363 N/A GLY 326.A N VAL 346.A O no hydrogen 2.892 N/A CYS 328.A N VAL 344.A O no hydrogen 3.016 N/A VAL 330.A N ALA 342.A O no hydrogen 3.017 N/A HIS 331.A N GLN 368.A O no hydrogen 2.914 N/A SER 332.A OG THR 334.A O no hydrogen 2.489 N/A MET 333.A N ARG 366.A O no hydrogen 3.193 N/A THR 334.A N SER 332.A OG no hydrogen 2.724 N/A THR 338.A N SER 357.A O no hydrogen 2.906 N/A ARG 340.A N SER 355.A O no hydrogen 3.253 N/A ARG 340.A NH1 SER 357.A OG no hydrogen 2.876 N/A ARG 340.A NH2 SER 357.A OG no hydrogen 2.505 N/A VAL 344.A N CYS 328.A O no hydrogen 2.883 N/A VAL 346.A N GLY 326.A O no hydrogen 2.901 N/A GLU 347.A N TYR 320.A OH no hydrogen 3.289 N/A SER 350.A OG GLN 351.A O no hydrogen 2.975 N/A LEU 352.A N ILE 318.A O no hydrogen 2.899 N/A GLN 353.A N GLN 353.A OE1 no hydrogen 2.856 N/A ILE 354.A N ALA 316.A O no hydrogen 2.862 N/A SER 355.A OG GLU 341.A OE1 no hydrogen 3.315 N/A PHE 356.A N GLY 314.A O no hydrogen 2.884 N/A SER 357.A N THR 338.A O no hydrogen 2.967 N/A SER 357.A OG ASP 311.A O no hydrogen 2.314 N/A LEU 360.A N THR 358.A OG1 no hydrogen 3.153 N/A SER 362.A OG SER 403.A O no hydrogen 2.423 N/A PHE 365.A N CYS 376.A O no hydrogen 2.986 N/A VAL 367.A N VAL 374.A O no hydrogen 2.889 N/A GLN 368.A N HIS 331.A O no hydrogen 2.846 N/A VAL 369.A N THR 372.A O no hydrogen 2.886 N/A CYS 370.A N ALA 329.A O no hydrogen 3.181 N/A CYS 370.A SG PRO 294.A O no hydrogen 3.261 N/A SER 371.A OG CYS 370.A O no hydrogen 2.544 N/A THR 372.A N GLN 368.A OE1 no hydrogen 2.570 N/A THR 372.A OG1 VAL 296.A O no hydrogen 3.245 N/A THR 372.A OG1 CYS 370.A O no hydrogen 3.488 N/A VAL 374.A N VAL 367.A O no hydrogen 2.927 N/A CYS 376.A N PHE 365.A O no hydrogen 2.940 N/A ALA 378.A N ALA 363.A O no hydrogen 2.854 N/A CYS 380.A N ALA 361.A O no hydrogen 2.627 N/A TYR 390.A OH ASP 311.A OD2 no hydrogen 2.768 N/A SER 393.A OG TYR 15.A OH no hydrogen 2.278 N/A THR 395.A OG1 ALA 392.A O no hydrogen 3.268 N/A THR 396.A OG1 SER 393.A O no hydrogen 3.152 N/A THR 396.A OG1 THR 396.A O no hydrogen 2.387 N/A SER 403.A OG THR 404.A O no hydrogen 3.556 N/A THR 405.A OG1 SER 408.A OG no hydrogen 2.468 N/A ALA 406.A N THR 404.A OG1 no hydrogen 2.564 N/A MET 407.A N THR 404.A O no hydrogen 2.944 N/A SER 408.A OG THR 405.A O no hydrogen 2.300 N/A SER 408.A OG THR 405.A OG1 no hydrogen 2.468 N/A TRP 409.A N THR 405.A O no hydrogen 2.820 N/A VAL 410.A N ALA 406.A O no hydrogen 2.892 N/A GLN 411.A N MET 407.A O no hydrogen 2.904 N/A LYS 412.A N SER 408.A O no hydrogen 2.877 N/A ILE 413.A N TRP 409.A O no hydrogen 2.950 N/A THR 414.A N VAL 410.A O no hydrogen 3.240 N/A GLY 415.A N ILE 413.A O no hydrogen 2.647 N/A VAL 421.A N VAL 417.A O no hydrogen 3.056 N/A ALA 422.A N GLY 418.A O no hydrogen 2.841 N/A VAL 423.A N LEU 419.A O no hydrogen 2.969 N/A ALA 424.A N ILE 420.A O no hydrogen 2.964 N/A ALA 425.A N VAL 421.A O no hydrogen 2.916 N/A LEU 426.A N ALA 422.A O no hydrogen 2.922 N/A ILE 427.A N VAL 423.A O no hydrogen 2.878 N/A LEU 428.A N ALA 424.A O no hydrogen 3.005 N/A ILE 429.A N ALA 425.A O no hydrogen 2.933 N/A VAL 430.A N LEU 426.A O no hydrogen 2.895 N/A VAL 431.A N ILE 427.A O no hydrogen 3.018 N/A LEU 432.A N LEU 428.A O no hydrogen 2.932 N/A VAL 434.A N VAL 431.A O no hydrogen 3.075 N/A SER 435.A OG VAL 434.A O no hydrogen 2.788 N/A