Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6npz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A N GLU 8.A OE2 no hydrogen 2.600 N/A THR 5.A OG1 GLU 8.A OE2 no hydrogen 2.894 N/A GLU 8.A N THR 5.A O no hydrogen 3.317 N/A PHE 9.A N MET 6.A O no hydrogen 3.293 N/A GLU 10.A N LYS 27.A O no hydrogen 2.817 N/A TYR 11.A OH MET 6.A O no hydrogen 2.962 N/A LEU 12.A N LEU 25.A O no hydrogen 2.871 N/A LYS 13.A N LEU 25.A O no hydrogen 3.297 N/A LYS 13.A NZ THR 291.A O no hydrogen 2.740 N/A LYS 13.A NZ THR 293.A OG1 no hydrogen 3.242 N/A LEU 15.A N VAL 23.A O no hydrogen 2.908 N/A GLY 16.A N VAL 23.A O no hydrogen 3.321 N/A LYS 17.A NZ GLN 303.A OE1 no hydrogen 3.545 N/A LYS 22.A N ILE 39.A O no hydrogen 3.170 N/A VAL 23.A N GLY 16.A O no hydrogen 2.820 N/A ILE 24.A N MET 37.A O no hydrogen 2.881 N/A LEU 25.A N LYS 13.A O no hydrogen 2.628 N/A VAL 26.A N TYR 35.A O no hydrogen 2.904 N/A LYS 27.A N GLU 10.A O no hydrogen 2.931 N/A GLU 28.A N ARG 33.A O no hydrogen 2.810 N/A LYS 29.A N GLU 8.A O no hydrogen 3.081 N/A LYS 29.A NZ ASN 7.A O no hydrogen 2.903 N/A THR 31.A N GLU 28.A O no hydrogen 3.168 N/A THR 31.A OG1 GLU 28.A O no hydrogen 3.550 N/A THR 31.A OG1 GLU 28.A OE1 no hydrogen 2.806 N/A GLY 32.A N GLU 28.A O no hydrogen 2.813 N/A ARG 33.A N THR 31.A OG1 no hydrogen 3.245 N/A TYR 35.A N VAL 26.A O no hydrogen 2.910 N/A ALA 36.A N MET 86.A O no hydrogen 2.894 N/A MET 37.A N ILE 24.A O no hydrogen 2.794 N/A LYS 38.A N PHE 84.A O no hydrogen 2.808 N/A LYS 38.A NZ GLU 57.A OE1 no hydrogen 3.507 N/A LYS 38.A NZ GLU 57.A OE2 no hydrogen 3.005 N/A ILE 39.A N LYS 22.A O no hydrogen 2.945 N/A LEU 40.A N LEU 82.A O no hydrogen 2.881 N/A LYS 42.A N ASP 80.A O no hydrogen 3.151 N/A LYS 42.A NZ GLN 77.A OE1 no hydrogen 2.918 N/A LYS 42.A NZ THR 78.A O no hydrogen 2.882 N/A LYS 42.A NZ PRO 310.A O no hydrogen 2.807 N/A ILE 45.A N LYS 41.A O no hydrogen 3.180 N/A VAL 46.A N LYS 42.A O no hydrogen 3.020 N/A ALA 47.A N GLU 43.A O no hydrogen 2.974 N/A LYS 48.A N VAL 44.A O no hydrogen 2.865 N/A ASP 49.A N VAL 46.A O no hydrogen 3.153 N/A GLU 50.A N ILE 45.A O no hydrogen 2.664 N/A HIS 53.A ND1 GLU 50.A OE1 no hydrogen 2.960 N/A THR 54.A N GLU 50.A O no hydrogen 2.962 N/A THR 54.A OG1 GLU 50.A O no hydrogen 2.798 N/A LEU 55.A N VAL 51.A O no hydrogen 2.949 N/A THR 56.A N ALA 52.A O no hydrogen 2.955 N/A THR 56.A OG1 ALA 52.A O no hydrogen 2.991 N/A GLU 57.A N HIS 53.A O no hydrogen 3.034 N/A ASN 58.A N THR 54.A O no hydrogen 3.061 N/A ASN 58.A ND2 PHE 315.A O no hydrogen 2.792 N/A ARG 59.A N LEU 55.A O no hydrogen 2.954 N/A ARG 59.A NE GLU 157.A OE1 no hydrogen 3.244 N/A ARG 59.A NE GLU 157.A OE2 no hydrogen 3.424 N/A ARG 59.A NH2 GLU 157.A OE1 no hydrogen 2.716 N/A VAL 60.A N THR 56.A O no hydrogen 2.750 N/A LEU 61.A N GLU 57.A O no hydrogen 3.017 N/A GLN 62.A N ASN 58.A O no hydrogen 2.963 N/A GLN 62.A NE2 ASN 58.A OD1 no hydrogen 2.835 N/A GLN 62.A NE2 PHE 315.A O no hydrogen 3.691 N/A ASN 63.A N ARG 59.A O no hydrogen 2.965 N/A SER 64.A N LEU 61.A O no hydrogen 3.438 N/A SER 64.A OG VAL 60.A O no hydrogen 2.933 N/A ARG 65.A N TYR 122.A OH no hydrogen 2.934 N/A ARG 65.A NH1 TYR 316.A OH no hydrogen 3.206 N/A ARG 65.A NH2 TYR 316.A OH no hydrogen 3.369 N/A PHE 68.A N HIS 66.A ND1 no hydrogen 3.144 N/A LEU 69.A N HIS 66.A O no hydrogen 3.262 N/A THR 70.A N ILE 149.A O no hydrogen 2.978 N/A THR 70.A OG1 ILE 149.A O no hydrogen 3.164 N/A ALA 71.A N GLU 87.A OE1 no hydrogen 2.861 N/A LYS 73.A N VAL 85.A O no hydrogen 2.754 N/A TYR 74.A N VAL 85.A O no hydrogen 3.269 N/A TYR 74.A OH GLU 28.A OE2 no hydrogen 2.605 N/A SER 75.A N TYR 316.A O no hydrogen 2.973 N/A SER 75.A OG ASN 58.A OD1 no hydrogen 3.162 N/A SER 75.A OG PHE 315.A O no hydrogen 2.757 N/A PHE 76.A N CYS 83.A O no hydrogen 3.152 N/A GLN 77.A NE2 PHE 312.A O no hydrogen 2.794 N/A THR 78.A N ARG 81.A O no hydrogen 2.860 N/A ASP 80.A N THR 78.A OG1 no hydrogen 3.151 N/A ARG 81.A N THR 78.A OG1 no hydrogen 2.847 N/A LEU 82.A N LEU 40.A O no hydrogen 2.795 N/A CYS 83.A N PHE 76.A O no hydrogen 2.941 N/A PHE 84.A N LYS 38.A O no hydrogen 2.835 N/A VAL 85.A N TYR 74.A O no hydrogen 2.742 N/A MET 86.A N ALA 36.A O no hydrogen 2.896 N/A GLU 87.A N ALA 71.A O no hydrogen 2.901 N/A GLY 91.A N LEU 141.A O no hydrogen 2.758 N/A GLY 92.A N ALA 89.A O no hydrogen 3.397 N/A LEU 94.A N LEU 139.A O no hydrogen 2.811 N/A PHE 95.A N LEU 136.A O no hydrogen 3.342 N/A HIS 97.A N GLU 93.A O no hydrogen 3.451 N/A HIS 97.A NE2 GLY 91.A O no hydrogen 2.704 N/A LEU 98.A N LEU 94.A O no hydrogen 2.860 N/A SER 99.A N PHE 95.A O no hydrogen 3.003 N/A SER 99.A OG PHE 95.A O no hydrogen 3.038 N/A ARG 100.A N PHE 96.A O no hydrogen 3.192 N/A ARG 100.A NH1 ASP 297.A OD1 no hydrogen 3.211 N/A ARG 100.A NH2 PHE 96.A O no hydrogen 3.486 N/A GLU 101.A N HIS 97.A O no hydrogen 2.878 N/A ARG 102.A N LEU 98.A O no hydrogen 2.887 N/A VAL 103.A N GLU 101.A O no hydrogen 2.831 N/A PHE 104.A N MET 200.A O no hydrogen 2.804 N/A ARG 108.A N SER 105.A OG no hydrogen 2.879 N/A ARG 108.A NE TYR 112.A OH no hydrogen 3.213 N/A ARG 108.A NH1 GLU 101.A OE2 no hydrogen 3.113 N/A ARG 108.A NH2 TYR 112.A OH no hydrogen 3.161 N/A ALA 109.A N SER 105.A O no hydrogen 2.966 N/A ARG 110.A N GLU 106.A O no hydrogen 2.865 N/A ARG 110.A NE.A PHE 265.A O no hydrogen 2.678 N/A ARG 110.A NH2.A PHE 265.A O no hydrogen 3.169 N/A ARG 110.A NH2.B ASP 107.A OD1 no hydrogen 3.540 N/A PHE 111.A N ASP 107.A O no hydrogen 3.276 N/A TYR 112.A N ARG 108.A O no hydrogen 3.241 N/A GLY 113.A N ALA 109.A O no hydrogen 2.795 N/A ALA 114.A N ARG 110.A O no hydrogen 2.807 N/A GLU 115.A N PHE 111.A O no hydrogen 3.209 N/A ILE 116.A N TYR 112.A O no hydrogen 2.935 N/A VAL 117.A N GLY 113.A O no hydrogen 2.867 N/A SER 118.A N ALA 114.A O no hydrogen 3.022 N/A SER 118.A OG HIS 66.A NE2 no hydrogen 3.145 N/A ALA 119.A N GLU 115.A O no hydrogen 3.125 N/A LEU 120.A N ILE 116.A O no hydrogen 2.921 N/A ASP 121.A N VAL 117.A O no hydrogen 2.699 N/A TYR 122.A N SER 118.A O no hydrogen 3.019 N/A LEU 123.A N ALA 119.A O no hydrogen 2.883 N/A HIS 124.A N LEU 120.A O no hydrogen 2.896 N/A HIS 124.A ND1 ASP 256.A OD1 no hydrogen 3.246 N/A HIS 124.A ND1 ASP 256.A OD2 no hydrogen 2.842 N/A HIS 124.A NE2 ASP 189.A OD2 no hydrogen 2.841 N/A SER 125.A N ASP 121.A O no hydrogen 2.861 N/A SER 125.A OG ASP 121.A OD1 no hydrogen 3.530 N/A GLU 126.A N TYR 122.A O no hydrogen 2.919 N/A LYS 127.A N LEU 123.A O no hydrogen 3.310 N/A LYS 127.A NZ ASN 63.A O no hydrogen 2.817 N/A ASN 128.A N HIS 124.A O no hydrogen 3.269 N/A VAL 129.A N LEU 123.A O no hydrogen 2.879 N/A VAL 130.A N LYS 156.A O no hydrogen 3.007 N/A TYR 131.A N ASP 189.A OD2 no hydrogen 2.963 N/A TYR 131.A OH THR 150.A O no hydrogen 2.579 N/A TYR 131.A OH ASP 151.A O no hydrogen 2.985 N/A ARG 132.A N ASP 189.A OD1 no hydrogen 2.797 N/A ARG 132.A NE LEU 154.A O no hydrogen 2.748 N/A ARG 132.A NH1 TYR 184.A OH no hydrogen 2.968 N/A ARG 132.A NH2 LEU 154.A O no hydrogen 2.962 N/A LYS 135.A NZ THR 170.A OG1 no hydrogen 2.579 N/A LEU 136.A N TYR 173.A OH no hydrogen 3.322 N/A GLU 137.A N GLU 137.A OE1 no hydrogen 2.831 N/A ASN 138.A N LYS 135.A O no hydrogen 3.185 N/A ASN 138.A ND2 ASP 133.A O no hydrogen 3.088 N/A ASN 138.A ND2 ASP 133.A OD2 no hydrogen 3.072 N/A LEU 139.A N LEU 136.A O no hydrogen 3.240 N/A MET 140.A N LYS 148.A O no hydrogen 2.857 N/A LEU 141.A N GLY 92.A O no hydrogen 2.808 N/A ASP 142.A N HIS 146.A O no hydrogen 2.956 N/A GLY 145.A N ASP 142.A O no hydrogen 2.809 N/A HIS 146.A N ASP 142.A OD1 no hydrogen 2.983 N/A HIS 146.A ND1 GLU 115.A OE2 no hydrogen 2.574 N/A ILE 147.A N GLU 115.A OE1 no hydrogen 2.820 N/A LYS 148.A N MET 140.A O no hydrogen 2.682 N/A LYS 148.A NZ PRO 67.A O no hydrogen 2.768 N/A LYS 148.A NZ GLU 87.A OE1 no hydrogen 3.488 N/A LYS 148.A NZ GLU 87.A OE2 no hydrogen 2.618 N/A ILE 149.A N PHE 68.A O no hydrogen 2.884 N/A THR 150.A N ASN 138.A O no hydrogen 2.995 N/A THR 150.A OG1 ASP 151.A OD1 no hydrogen 3.446 N/A PHE 152.A N GLU 57.A OE1 no hydrogen 3.170 N/A CYS 155.A N PHE 152.A O no hydrogen 3.190 N/A CYS 155.A SG PHE 152.A O no hydrogen 3.475 N/A LYS 156.A N VAL 130.A O no hydrogen 2.995 N/A ILE 159.A N ASN 128.A O no hydrogen 2.974 N/A GLY 162.A N LYS 160.A O no hydrogen 2.542 N/A MET 165.A N TYR 184.A O no hydrogen 2.811 N/A LYS 166.A NZ ASP 183.A OD1 no hydrogen 2.845 N/A THR 170.A OG1 ASP 133.A OD1 no hydrogen 2.640 N/A TYR 173.A N THR 170.A O no hydrogen 2.966 N/A TYR 173.A OH GLU 199.A OE1 no hydrogen 2.384 N/A LEU 174.A N PRO 171.A O no hydrogen 3.313 N/A GLU 177.A N GLU 177.A OE1 no hydrogen 2.751 N/A VAL 178.A N ALA 175.A O no hydrogen 2.913 N/A LEU 179.A N ALA 175.A O no hydrogen 3.104 N/A GLU 180.A N PRO 176.A O no hydrogen 2.835 N/A ASP 181.A N VAL 178.A O no hydrogen 3.007 N/A TYR 184.A N MET 165.A O no hydrogen 3.106 N/A ARG 186.A NH1 ASP 161.A OD1 no hydrogen 3.131 N/A ARG 186.A NH2 ASP 161.A OD1 no hydrogen 3.476 N/A ARG 186.A NH2 SER 254.A O no hydrogen 3.451 N/A VAL 188.A N GLY 185.A O no hydrogen 3.284 N/A ASP 189.A N ARG 186.A O no hydrogen 3.191 N/A TRP 190.A N ALA 187.A O no hydrogen 3.171 N/A TRP 190.A NE1 ASP 256.A OD1 no hydrogen 2.866 N/A TRP 191.A N ALA 187.A O no hydrogen 3.315 N/A GLY 192.A N VAL 188.A O no hydrogen 3.203 N/A LEU 193.A N ASP 189.A O no hydrogen 3.021 N/A GLY 194.A N TRP 190.A O no hydrogen 2.989 N/A VAL 195.A N TRP 191.A O no hydrogen 2.967 N/A VAL 196.A N GLY 192.A O no hydrogen 2.958 N/A MET 197.A N LEU 193.A O no hydrogen 2.874 N/A TYR 198.A N GLY 194.A O no hydrogen 2.839 N/A TYR 198.A OH ARG 225.A O no hydrogen 2.701 N/A GLU 199.A N VAL 195.A O no hydrogen 2.977 N/A MET 200.A N VAL 196.A O no hydrogen 2.934 N/A MET 201.A N MET 197.A O no hydrogen 3.000 N/A CYS 202.A N TYR 198.A O no hydrogen 2.738 N/A GLY 203.A N GLU 199.A O no hydrogen 2.860 N/A ASP 211.A N ASN 209.A OD1 no hydrogen 3.007 N/A LYS 214.A N ASP 211.A OD2 no hydrogen 3.215 N/A LEU 215.A N ASP 211.A O no hydrogen 2.956 N/A PHE 216.A N HIS 212.A O no hydrogen 2.905 N/A PHE 216.A N GLU 213.A O no hydrogen 3.185 N/A GLU 217.A N GLU 213.A O no hydrogen 3.153 N/A LEU 218.A N LYS 214.A O no hydrogen 3.034 N/A ILE 219.A N LEU 215.A O no hydrogen 3.062 N/A LEU 220.A N PHE 216.A O no hydrogen 2.883 N/A MET 221.A N GLU 217.A O no hydrogen 2.940 N/A MET 221.A N LEU 218.A O no hydrogen 3.194 N/A GLU 222.A N LEU 218.A O no hydrogen 2.795 N/A LEU 230.A N PRO 227.A O no hydrogen 3.117 N/A GLY 231.A N GLU 106.A OE2 no hydrogen 3.072 N/A GLU 233.A N GLU 233.A OE2 no hydrogen 2.781 N/A LYS 235.A N GLY 231.A O no hydrogen 2.937 N/A SER 236.A N PRO 232.A O no hydrogen 2.911 N/A SER 236.A OG HIS 263.A NE2 no hydrogen 2.879 N/A LEU 237.A N GLU 233.A O no hydrogen 2.890 N/A LEU 238.A N ALA 234.A O no hydrogen 2.816 N/A SER 239.A N LYS 235.A O no hydrogen 2.971 N/A SER 239.A OG LYS 235.A O no hydrogen 2.927 N/A GLY 240.A N SER 236.A O no hydrogen 3.008 N/A LEU 241.A N LEU 237.A O no hydrogen 2.922 N/A LEU 242.A N LEU 238.A O no hydrogen 2.909 N/A LYS 243.A NZ SER 239.A O no hydrogen 3.499 N/A LYS 244.A NZ ILE 219.A O no hydrogen 2.847 N/A LYS 244.A NZ GLU 222.A O no hydrogen 2.828 N/A LYS 247.A N ASP 245.A OD1 no hydrogen 2.825 N/A GLN 248.A N ASP 245.A O no hydrogen 2.956 N/A ARG 249.A N PRO 246.A O no hydrogen 3.200 N/A ARG 249.A NE LYS 243.A O no hydrogen 2.935 N/A ARG 249.A NH1 GLU 177.A OE1 no hydrogen 3.544 N/A ARG 249.A NH1 GLU 177.A OE2 no hydrogen 2.809 N/A ARG 249.A NH1 ALA 187.A O no hydrogen 2.935 N/A ARG 249.A NH2 GLU 177.A OE1 no hydrogen 2.924 N/A ARG 249.A NH2 LYS 243.A O no hydrogen 2.834 N/A LEU 250.A N GLY 240.A O no hydrogen 2.972 N/A GLY 251.A N GLU 259.A OE1 no hydrogen 2.876 N/A GLY 252.A N ARG 249.A O no hydrogen 2.797 N/A ASP 256.A N GLY 253.A O no hydrogen 3.186 N/A LYS 258.A N GLU 255.A O no hydrogen 3.079 N/A LYS 258.A NZ ASP 121.A OD1 no hydrogen 2.757 N/A LYS 258.A NZ ASP 121.A OD2 no hydrogen 3.339 N/A GLU 259.A N ASP 256.A O no hydrogen 3.195 N/A MET 261.A N ALA 257.A O no hydrogen 2.865 N/A GLN 262.A N LYS 258.A O no hydrogen 3.140 N/A HIS 263.A N ILE 260.A O no hydrogen 2.935 N/A HIS 263.A NE2 SER 236.A OG no hydrogen 2.879 N/A ARG 264.A NH1 SER 236.A OG no hydrogen 2.977 N/A PHE 265.A N HIS 263.A ND1 no hydrogen 2.977 N/A PHE 266.A N HIS 263.A O no hydrogen 2.828 N/A ALA 267.A N ARG 264.A O no hydrogen 2.977 N/A ILE 269.A N PHE 266.A O no hydrogen 2.989 N/A TRP 271.A NE1 MET 261.A O no hydrogen 3.187 N/A GLN 272.A NE2 GLU 276.A OE2 no hydrogen 2.823 N/A HIS 273.A N VAL 270.A O no hydrogen 2.887 N/A VAL 274.A N VAL 270.A O no hydrogen 2.943 N/A TYR 275.A N TRP 271.A O no hydrogen 3.142 N/A GLU 276.A N GLN 272.A O no hydrogen 3.112 N/A LYS 277.A N VAL 274.A O no hydrogen 2.986 N/A LYS 278.A N HIS 273.A O no hydrogen 2.984 N/A LYS 278.A NZ GLU 276.A OE1 no hydrogen 3.057 N/A GLN 286.A N TYR 295.A OH no hydrogen 2.828 N/A GLN 286.A NE2 LYS 284.A O no hydrogen 2.727 N/A THR 288.A N ASP 292.A OD2 no hydrogen 2.990 N/A THR 288.A OG1 ASP 292.A OD2 no hydrogen 3.152 N/A ASP 292.A N SER 289.A O no hydrogen 3.325 N/A ARG 294.A N ASP 292.A OD1 no hydrogen 3.152 N/A ARG 294.A NE ASP 292.A OD1 no hydrogen 3.472 N/A PHE 296.A N THR 293.A O no hydrogen 3.167 N/A PHE 300.A N ASP 297.A O no hydrogen 3.231 N/A THR 301.A N ASP 297.A O no hydrogen 3.259 N/A THR 301.A OG1 ASP 297.A O no hydrogen 3.317 N/A ALA 302.A N GLU 298.A O no hydrogen 3.294 N/A GLN 303.A N PHE 300.A O no hydrogen 2.894 N/A GLN 303.A NE2 PHE 300.A O no hydrogen 3.285 N/A ILE 307.A N TYR 11.A O no hydrogen 3.487 N/A PHE 312.A N GLN 77.A OE1 no hydrogen 2.767 N/A SER 317.A OG HIS 2.A O no hydrogen 2.506 N/A ALA 318.A N LYS 73.A O no hydrogen 2.905 N/A