Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6o8u_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 3.A N LEU 80.A O no hydrogen 3.337 N/A PHE 5.A N PHE 82.A O no hydrogen 2.837 N/A PHE 7.A N ASP 85.A OD1 no hydrogen 3.162 N/A GLU 9.A N SER 6.A OG no hydrogen 3.294 N/A LEU 10.A N SER 6.A O no hydrogen 3.433 N/A LYS 11.A N PHE 7.A O no hydrogen 3.115 N/A ASN 12.A N TYR 8.A O no hydrogen 3.420 N/A VAL 13.A N GLU 9.A O no hydrogen 3.209 N/A THR 14.A N LEU 10.A O no hydrogen 3.085 N/A THR 14.A OG1 LEU 10.A O no hydrogen 2.657 N/A ASN 16.A N LYS 11.A O no hydrogen 2.644 N/A PHE 17.A N THR 14.A OG1 no hydrogen 3.202 N/A VAL 24.A N PRO 21.A O no hydrogen 3.315 N/A GLY 25.A N ILE 22.A O no hydrogen 3.425 N/A GLY 26.A N PRO 21.A O no hydrogen 2.750 N/A LYS 28.A N GLU 19.A O no hydrogen 2.810 N/A MET 29.A N VAL 37.A O no hydrogen 2.950 N/A VAL 36.A N LYS 51.A O no hydrogen 2.977 N/A VAL 37.A N GLY 30.A O no hydrogen 3.025 N/A TYR 38.A N VAL 49.A O no hydrogen 2.747 N/A LYS 39.A N ASN 27.A O no hydrogen 3.084 N/A LYS 39.A NZ TYR 95.A OH no hydrogen 3.557 N/A GLY 40.A N VAL 47.A O no hydrogen 3.087 N/A VAL 42.A N THR 45.A O no hydrogen 2.971 N/A THR 45.A N VAL 42.A O no hydrogen 2.915 N/A THR 45.A OG1 VAL 42.A O no hydrogen 3.472 N/A VAL 47.A N GLY 40.A O no hydrogen 2.932 N/A ALA 48.A N TYR 93.A O no hydrogen 2.981 N/A VAL 49.A N TYR 38.A O no hydrogen 2.738 N/A LYS 50.A N LEU 91.A O no hydrogen 2.766 N/A LYS 50.A NZ ASP 160.A OD1 no hydrogen 2.687 N/A LYS 51.A N VAL 36.A O no hydrogen 2.882 N/A LEU 52.A N LEU 89.A O no hydrogen 3.259 N/A THR 53.A OG1 GLU 56.A OE2 no hydrogen 2.721 N/A LEU 57.A N THR 53.A O no hydrogen 3.207 N/A LYS 58.A N THR 54.A O no hydrogen 2.808 N/A GLN 59.A N GLU 55.A O no hydrogen 2.957 N/A GLN 60.A N GLU 56.A O no hydrogen 3.043 N/A PHE 61.A N LEU 57.A O no hydrogen 3.055 N/A ASP 62.A N LYS 58.A O no hydrogen 3.086 N/A GLN 63.A N GLN 59.A O no hydrogen 2.944 N/A GLU 64.A N GLN 60.A O no hydrogen 2.878 N/A ILE 65.A N PHE 61.A O no hydrogen 3.247 N/A LYS 66.A N ASP 62.A O no hydrogen 2.926 N/A VAL 67.A N GLN 63.A O no hydrogen 2.953 N/A MET 68.A N GLU 64.A O no hydrogen 2.993 N/A ALA 69.A N ILE 65.A O no hydrogen 2.916 N/A LYS 70.A N LYS 66.A O no hydrogen 3.343 N/A CYS 71.A N VAL 67.A O no hydrogen 2.915 N/A ASN 75.A N HIS 73.A ND1 no hydrogen 3.281 N/A ASN 75.A ND2 ALA 156.A O no hydrogen 3.028 N/A LEU 76.A N HIS 73.A O no hydrogen 2.958 N/A VAL 77.A N ILE 158.A O no hydrogen 2.954 N/A LEU 80.A N VAL 92.A O no hydrogen 2.702 N/A GLY 81.A N VAL 92.A O no hydrogen 3.269 N/A PHE 82.A N HIS 3.A O no hydrogen 3.206 N/A SER 83.A N CYS 90.A O no hydrogen 3.260 N/A CYS 90.A N SER 83.A O no hydrogen 3.229 N/A LEU 91.A N LYS 50.A O no hydrogen 3.017 N/A VAL 92.A N GLY 81.A O no hydrogen 3.008 N/A TYR 93.A N ALA 48.A O no hydrogen 2.766 N/A TYR 93.A OH GLU 64.A OE1 no hydrogen 2.744 N/A VAL 94.A N GLU 78.A O no hydrogen 2.982 N/A ASN 98.A N LEU 150.A O no hydrogen 3.076 N/A ASN 98.A ND2 ASP 151.A O no hydrogen 2.730 N/A ASN 98.A ND2 GLU 152.A O no hydrogen 3.394 N/A GLY 99.A N MET 96.A O no hydrogen 3.102 N/A LEU 101.A N ILE 148.A O no hydrogen 2.770 N/A LEU 102.A N SER 145.A O no hydrogen 3.138 N/A ASP 103.A N SER 100.A OG no hydrogen 3.095 N/A ARG 104.A N SER 100.A O no hydrogen 3.029 N/A ARG 104.A NE THR 111.A OG1 no hydrogen 2.958 N/A ARG 104.A NH1 LEU 108.A O no hydrogen 2.930 N/A ARG 104.A NH1 THR 111.A OG1 no hydrogen 3.254 N/A ARG 104.A NH2 ASN 98.A O no hydrogen 2.829 N/A LEU 105.A N LEU 101.A O no hydrogen 2.800 N/A SER 106.A N LEU 102.A O no hydrogen 3.053 N/A SER 106.A OG LEU 102.A O no hydrogen 3.203 N/A SER 106.A OG ASP 103.A O no hydrogen 2.976 N/A CYS 107.A N ARG 104.A O no hydrogen 3.218 N/A CYS 107.A SG ARG 104.A O no hydrogen 3.946 N/A LEU 108.A N ASP 103.A O no hydrogen 3.001 N/A GLY 110.A N CYS 107.A O no hydrogen 3.340 N/A THR 111.A OG1 LEU 108.A O no hydrogen 3.324 N/A TRP 116.A N ASP 243.A OD1 no hydrogen 2.841 N/A TRP 116.A NE1 SER 248.A OG no hydrogen 2.645 N/A HIS 117.A N ASP 243.A OD2 no hydrogen 3.102 N/A MET 118.A N SER 115.A OG no hydrogen 3.082 N/A ARG 119.A N SER 115.A O no hydrogen 2.916 N/A ARG 119.A NE LEU 114.A O no hydrogen 2.881 N/A ARG 119.A NH1 ILE 203.A O no hydrogen 2.730 N/A ARG 119.A NH1 ASP 238.A OD2 no hydrogen 2.887 N/A ARG 119.A NH2 LEU 114.A O no hydrogen 2.943 N/A ARG 119.A NH2 ASP 238.A OD2 no hydrogen 3.006 N/A CYS 120.A N TRP 116.A O no hydrogen 2.959 N/A CYS 120.A SG TRP 116.A O no hydrogen 3.407 N/A LYS 121.A N HIS 117.A O no hydrogen 3.274 N/A ILE 122.A N MET 118.A O no hydrogen 2.920 N/A ALA 123.A N ARG 119.A O no hydrogen 2.973 N/A GLN 124.A N CYS 120.A O no hydrogen 3.047 N/A GLN 124.A NE2 CYS 120.A O no hydrogen 3.439 N/A GLY 125.A N LYS 121.A O no hydrogen 2.895 N/A ALA 126.A N ILE 122.A O no hydrogen 2.906 N/A ALA 127.A N ALA 123.A O no hydrogen 3.017 N/A ASN 128.A N GLN 124.A O no hydrogen 2.976 N/A GLY 129.A N GLY 125.A O no hydrogen 2.993 N/A ILE 130.A N ALA 126.A O no hydrogen 3.007 N/A ASN 131.A N ALA 127.A O no hydrogen 2.819 N/A ASN 131.A ND2 GLU 135.A OE2 no hydrogen 3.106 N/A PHE 132.A N ASN 128.A O no hydrogen 3.026 N/A LEU 133.A N GLY 129.A O no hydrogen 3.100 N/A HIS 134.A N ILE 130.A O no hydrogen 2.938 N/A HIS 134.A NE2 ASP 192.A OD2 no hydrogen 2.911 N/A GLU 135.A N ASN 131.A O no hydrogen 2.744 N/A ASN 136.A N PHE 132.A O no hydrogen 3.026 N/A ASN 136.A ND2 PHE 132.A O no hydrogen 2.788 N/A HIS 137.A N HIS 134.A O no hydrogen 3.038 N/A HIS 138.A N LEU 133.A O no hydrogen 2.957 N/A HIS 138.A ND1 ASN 136.A O no hydrogen 2.768 N/A ILE 139.A N ARG 165.A O no hydrogen 2.814 N/A HIS 140.A N ASP 192.A OD2 no hydrogen 2.844 N/A HIS 140.A NE2 SER 159.A O no hydrogen 2.820 N/A ARG 141.A N ASP 192.A OD1 no hydrogen 2.983 N/A ARG 141.A NE LEU 163.A O no hydrogen 2.860 N/A ARG 141.A NH2 LEU 163.A O no hydrogen 3.113 N/A LYS 144.A NZ THR 174.A OG1 no hydrogen 2.940 N/A SER 145.A OG TYR 177.A OH no hydrogen 3.128 N/A SER 145.A OG GLU 202.A OE1 no hydrogen 3.222 N/A SER 145.A OG GLU 202.A OE2 no hydrogen 2.598 N/A ASN 147.A N LYS 144.A O no hydrogen 2.935 N/A ASN 147.A ND2 ASP 142.A O no hydrogen 2.968 N/A ILE 148.A N SER 145.A O no hydrogen 3.426 N/A LEU 149.A N LYS 157.A O no hydrogen 2.756 N/A LEU 150.A N GLY 99.A O no hydrogen 2.816 N/A ASP 151.A N THR 155.A O no hydrogen 3.238 N/A ALA 153.A N ASP 151.A OD1 no hydrogen 2.995 N/A PHE 154.A N ASP 151.A O no hydrogen 3.047 N/A THR 155.A N ASP 151.A OD1 no hydrogen 2.879 N/A THR 155.A OG1 ASP 151.A OD1 no hydrogen 3.548 N/A LYS 157.A N LEU 149.A O no hydrogen 2.725 N/A LYS 157.A NZ GLU 74.A O no hydrogen 2.666 N/A ILE 158.A N ASN 75.A O no hydrogen 2.846 N/A SER 159.A N ASN 147.A O no hydrogen 2.926 N/A SER 159.A OG ASN 147.A O no hydrogen 3.085 N/A PHE 161.A N GLU 64.A OE2 no hydrogen 2.802 N/A ALA 164.A N PHE 161.A O no hydrogen 3.273 N/A ARG 165.A N ILE 139.A O no hydrogen 2.981 N/A SER 167.A N ARG 165.A O no hydrogen 3.183 N/A THR 174.A OG1 ASP 142.A OD1 no hydrogen 3.074 N/A TYR 177.A N THR 174.A O no hydrogen 2.869 N/A TYR 177.A OH SER 145.A OG no hydrogen 3.128 N/A TYR 177.A OH GLU 202.A OE1 no hydrogen 2.700 N/A TYR 177.A OH GLU 202.A OE2 no hydrogen 3.168 N/A MET 178.A N THR 175.A O no hydrogen 3.167 N/A GLU 181.A N GLU 181.A OE2 no hydrogen 2.915 N/A LEU 183.A N ALA 179.A O no hydrogen 3.059 N/A ARG 184.A N.A PRO 180.A O no hydrogen 2.944 N/A ARG 184.A N.B PRO 180.A O no hydrogen 2.940 N/A GLY 185.A N ALA 182.A O no hydrogen 3.161 N/A GLU 186.A N GLU 181.A O no hydrogen 2.879 N/A ILE 187.A N VAL 168.A O no hydrogen 2.845 N/A LYS 190.A N THR 188.A OG1 no hydrogen 3.118 N/A LYS 190.A NZ ASN 265.A OD1 no hydrogen 2.702 N/A SER 191.A N THR 188.A O no hydrogen 3.091 N/A SER 191.A OG GLU 181.A OE1 no hydrogen 2.740 N/A ILE 193.A N PRO 189.A O no hydrogen 3.422 N/A TYR 194.A N LYS 190.A O no hydrogen 3.322 N/A SER 195.A N SER 191.A O no hydrogen 3.152 N/A SER 195.A OG TYR 177.A O no hydrogen 2.730 N/A SER 195.A OG SER 191.A O no hydrogen 3.201 N/A PHE 196.A N ASP 192.A O no hydrogen 2.966 N/A GLY 197.A N ILE 193.A O no hydrogen 3.002 N/A VAL 198.A N TYR 194.A O no hydrogen 3.229 N/A VAL 199.A N SER 195.A O no hydrogen 3.110 N/A LEU 200.A N PHE 196.A O no hydrogen 2.857 N/A LEU 201.A N GLY 197.A O no hydrogen 3.083 N/A GLU 202.A N VAL 198.A O no hydrogen 3.002 N/A ILE 203.A N VAL 199.A O no hydrogen 2.940 N/A ILE 204.A N LEU 200.A O no hydrogen 3.021 N/A THR 205.A N LEU 201.A O no hydrogen 2.996 N/A THR 205.A OG1 LEU 201.A O no hydrogen 2.698 N/A GLY 206.A N GLU 202.A O no hydrogen 2.761 N/A LEU 207.A N THR 205.A OG1 no hydrogen 3.167 N/A ASP 211.A N GLN 217.A O no hydrogen 2.921 N/A HIS 213.A N ASP 211.A OD1 no hydrogen 3.127 N/A ARG 214.A NH1 PRO 208.A O no hydrogen 2.625 N/A ARG 214.A NH2 PRO 216.A O no hydrogen 3.193 N/A LEU 219.A N ALA 209.A O no hydrogen 2.845 N/A ASP 221.A N LEU 218.A O no hydrogen 3.123 N/A ILE 222.A N LEU 219.A O no hydrogen 3.118 N/A LYS 223.A N LEU 220.A O no hydrogen 3.401 N/A GLU 224.A N ASP 221.A O no hydrogen 3.270 N/A GLU 225.A N ASP 221.A O no hydrogen 3.481 N/A ILE 226.A N ILE 222.A O no hydrogen 2.910 N/A GLU 227.A N LYS 223.A O no hydrogen 2.939 N/A ASP 228.A N GLU 224.A O no hydrogen 3.003 N/A GLU 229.A N ILE 226.A O no hydrogen 3.286 N/A GLU 230.A N GLU 225.A O no hydrogen 3.169 N/A LYS 231.A N GLU 225.A O no hydrogen 3.343 N/A THR 232.A N ASP 235.A OD2 no hydrogen 3.042 N/A THR 232.A OG1 ASP 235.A OD2 no hydrogen 3.059 N/A ASP 235.A N THR 232.A OG1 no hydrogen 3.197 N/A TYR 236.A N ILE 233.A O no hydrogen 3.128 N/A TYR 236.A OH GLU 225.A OE1 no hydrogen 2.484 N/A ILE 237.A N ILE 233.A O no hydrogen 3.046 N/A ASP 238.A N ILE 204.A O no hydrogen 2.865 N/A LYS 240.A N ASP 238.A OD1 no hydrogen 2.956 N/A LYS 240.A NZ ASP 238.A OD1 no hydrogen 2.973 N/A SER 248.A N ASP 245.A OD2 no hydrogen 3.216 N/A SER 248.A OG ASP 245.A O no hydrogen 3.462 N/A SER 248.A OG ASP 245.A OD1 no hydrogen 2.617 N/A VAL 249.A N ASP 245.A O no hydrogen 3.235 N/A GLU 250.A N SER 246.A O no hydrogen 2.877 N/A ALA 251.A N THR 247.A O no hydrogen 2.944 N/A MET 252.A N SER 248.A O no hydrogen 2.945 N/A TYR 253.A N VAL 249.A O no hydrogen 2.944 N/A SER 254.A N GLU 250.A O no hydrogen 2.980 N/A VAL 255.A N ALA 251.A O no hydrogen 3.217 N/A ALA 256.A N MET 252.A O no hydrogen 2.923 N/A SER 257.A N TYR 253.A O no hydrogen 2.760 N/A GLN 258.A N SER 254.A O no hydrogen 3.090 N/A GLN 258.A NE2 SER 254.A O no hydrogen 3.036 N/A GLN 258.A NE2 SER 254.A OG no hydrogen 3.220 N/A CYS 259.A N VAL 255.A O no hydrogen 2.925 N/A CYS 259.A SG VAL 255.A O no hydrogen 3.260 N/A LEU 260.A N ALA 256.A O no hydrogen 2.976 N/A HIS 261.A N GLN 258.A O no hydrogen 3.317 N/A GLU 262.A N.B GLU 262.A OE1.B no hydrogen 2.323 N/A LYS 264.A NZ GLU 186.A OE2 no hydrogen 2.901 N/A LYS 266.A N LYS 263.A O no hydrogen 3.218 N/A ARG 267.A N LYS 264.A O no hydrogen 3.374 N/A ARG 267.A NE HIS 261.A O no hydrogen 2.720 N/A ARG 267.A NH1 GLU 181.A OE1 no hydrogen 2.662 N/A ARG 267.A NH1 GLU 181.A OE2 no hydrogen 3.455 N/A ARG 267.A NH1 LYS 190.A O no hydrogen 3.059 N/A ARG 267.A NH2 GLU 181.A OE2 no hydrogen 2.856 N/A ARG 267.A NH2 HIS 261.A O no hydrogen 3.274 N/A ARG 267.A NH2 GLU 262.A O.A no hydrogen 3.456 N/A ARG 267.A NH2 GLU 262.A O.B no hydrogen 3.218 N/A LYS 271.A NZ GLN 274.A OE1 no hydrogen 2.889 N/A LYS 272.A N ASP 269.A OD1 no hydrogen 3.124 N/A VAL 273.A N ASP 269.A O no hydrogen 3.126 N/A GLN 274.A N ILE 270.A O no hydrogen 2.911 N/A GLN 274.A NE2 ASN 128.A OD1 no hydrogen 2.497 N/A GLN 275.A N LYS 271.A O no hydrogen 3.059 N/A LEU 276.A N LYS 272.A O no hydrogen 2.857 N/A LEU 277.A N VAL 273.A O no hydrogen 3.015 N/A GLN 278.A N GLN 274.A O no hydrogen 2.955 N/A GLU 279.A N GLN 275.A O no hydrogen 2.916 N/A MET 280.A N LEU 276.A O no hydrogen 3.046 N/A THR 281.A N LEU 277.A O no hydrogen 3.355 N/A THR 281.A OG1 GLN 124.A OE1 no hydrogen 2.629 N/A THR 281.A OG1 LEU 277.A O no hydrogen 3.406 N/A