Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6r4b_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 3.A N ASP 6.A OD2 no hydrogen 2.862 N/A ASP 6.A N ALA 3.A O no hydrogen 2.954 N/A PHE 7.A N LEU 4.A O no hydrogen 3.104 N/A GLU 8.A N ARG 25.A O no hydrogen 2.958 N/A GLY 10.A N LEU 23.A O no hydrogen 2.756 N/A ARG 11.A NH1 PRO 12.A O no hydrogen 2.884 N/A LEU 13.A N VAL 21.A O no hydrogen 2.717 N/A GLY 14.A N VAL 21.A O no hydrogen 3.395 N/A GLY 16.A N GLY 19.A O no hydrogen 2.523 N/A ASN 20.A N VAL 37.A O no hydrogen 2.957 N/A VAL 21.A N GLY 14.A O no hydrogen 2.995 N/A TYR 22.A N LEU 35.A O no hydrogen 2.870 N/A LEU 23.A N ARG 11.A O no hydrogen 2.995 N/A ALA 24.A N LEU 33.A O no hydrogen 2.987 N/A ARG 25.A N GLU 8.A O no hydrogen 2.962 N/A ARG 25.A NH2 GLU 8.A OE1 no hydrogen 3.020 N/A GLU 26.A N PHE 31.A O no hydrogen 2.939 N/A LYS 27.A N ASP 6.A O no hydrogen 2.942 N/A LYS 27.A NZ GLU 5.A O no hydrogen 3.132 N/A GLN 28.A N GLU 26.A OE2 no hydrogen 3.020 N/A SER 29.A N GLU 26.A OE1 no hydrogen 2.701 N/A SER 29.A OG GLU 26.A OE1 no hydrogen 2.724 N/A LYS 30.A N GLU 26.A O no hydrogen 2.740 N/A PHE 31.A N SER 29.A OG no hydrogen 3.087 N/A LEU 33.A N ALA 24.A O no hydrogen 2.905 N/A ALA 34.A N LEU 84.A O no hydrogen 2.987 N/A LEU 35.A N TYR 22.A O no hydrogen 2.757 N/A LYS 36.A N LEU 82.A O no hydrogen 2.930 N/A LYS 36.A NZ GLU 55.A OE2 no hydrogen 2.891 N/A VAL 37.A N ASN 20.A O no hydrogen 2.927 N/A LEU 38.A N VAL 80.A O no hydrogen 2.839 N/A LYS 40.A N THR 78.A O no hydrogen 2.911 N/A LYS 40.A NZ HIS 75.A ND1 no hydrogen 3.112 N/A LYS 40.A NZ ASP 76.A O no hydrogen 2.758 N/A GLN 42.A NE2 LYS 17.A O no hydrogen 3.398 N/A LEU 43.A N PHE 39.A O no hydrogen 2.982 N/A GLU 44.A N LYS 40.A O no hydrogen 2.992 N/A LYS 45.A N ALA 41.A O no hydrogen 2.853 N/A ALA 46.A N GLN 42.A O no hydrogen 3.086 N/A VAL 48.A N LEU 43.A O no hydrogen 3.069 N/A GLU 49.A N GLU 49.A OE1 no hydrogen 2.907 N/A GLN 51.A N VAL 48.A O no hydrogen 3.158 N/A LEU 52.A N VAL 48.A O no hydrogen 3.435 N/A ARG 53.A N GLU 49.A O no hydrogen 3.175 N/A ARG 54.A N HIS 50.A O no hydrogen 3.124 N/A GLU 55.A N GLN 51.A O no hydrogen 2.856 N/A VAL 56.A N LEU 52.A O no hydrogen 3.063 N/A GLU 57.A N ARG 53.A O no hydrogen 2.955 N/A ILE 58.A N ARG 54.A O no hydrogen 2.894 N/A GLN 59.A N GLU 55.A O no hydrogen 3.115 N/A GLN 59.A NE2 LEU 68.A O no hydrogen 2.891 N/A SER 60.A N VAL 56.A O no hydrogen 3.163 N/A SER 60.A OG VAL 56.A O no hydrogen 2.819 N/A SER 60.A OG GLU 57.A O no hydrogen 3.294 N/A HIS 61.A N ILE 58.A O no hydrogen 3.251 N/A LEU 62.A N ILE 58.A O no hydrogen 3.205 N/A ARG 63.A N TYR 120.A OH no hydrogen 3.231 N/A ARG 63.A NH2 SER 60.A O no hydrogen 3.282 N/A ASN 66.A N HIS 64.A ND1 no hydrogen 3.094 N/A ASN 66.A ND2 LEU 144.A O no hydrogen 3.034 N/A ILE 67.A N HIS 64.A O no hydrogen 2.990 N/A LEU 68.A N ILE 146.A O no hydrogen 3.033 N/A ARG 69.A N GLU 85.A OE1 no hydrogen 2.960 N/A TYR 71.A N ILE 83.A O no hydrogen 2.797 N/A PHE 74.A N TYR 81.A O no hydrogen 3.148 N/A ASP 76.A N ARG 79.A O no hydrogen 3.010 N/A THR 78.A N ASP 76.A OD1 no hydrogen 3.157 N/A ARG 79.A N ASP 76.A OD1 no hydrogen 2.931 N/A ARG 79.A NE TYR 81.A OH no hydrogen 2.717 N/A ARG 79.A NH2 ASP 76.A OD2 no hydrogen 3.190 N/A ARG 79.A NH2 TYR 81.A OH no hydrogen 3.422 N/A VAL 80.A N LEU 38.A O no hydrogen 2.826 N/A TYR 81.A N PHE 74.A O no hydrogen 2.814 N/A TYR 81.A OH ASP 76.A OD2 no hydrogen 2.760 N/A LEU 82.A N LYS 36.A O no hydrogen 2.836 N/A ILE 83.A N GLY 72.A O no hydrogen 2.737 N/A LEU 84.A N ALA 34.A O no hydrogen 2.878 N/A GLU 85.A N ARG 69.A O no hydrogen 3.071 N/A LEU 89.A N LEU 138.A O no hydrogen 3.112 N/A GLY 90.A N ALA 87.A O no hydrogen 3.445 N/A VAL 92.A N LEU 136.A O no hydrogen 2.879 N/A TYR 93.A N PRO 133.A O no hydrogen 3.314 N/A ARG 94.A N THR 91.A OG1 no hydrogen 2.928 N/A GLU 95.A N THR 91.A O no hydrogen 3.213 N/A LEU 96.A N VAL 92.A O no hydrogen 2.963 N/A GLN 97.A N TYR 93.A O no hydrogen 3.075 N/A LYS 98.A N ARG 94.A O no hydrogen 2.999 N/A LYS 98.A NZ GLU 95.A OE1 no hydrogen 2.826 N/A LYS 98.A NZ GLU 95.A OE2 no hydrogen 3.425 N/A LEU 99.A N GLU 95.A O no hydrogen 3.056 N/A SER 100.A N LEU 96.A O no hydrogen 2.953 N/A PHE 102.A N PHE 195.A O no hydrogen 2.855 N/A ARG 106.A N ASP 103.A OD1 no hydrogen 2.692 N/A THR 107.A N ASP 103.A O no hydrogen 3.025 N/A THR 107.A OG1 ASP 103.A O no hydrogen 2.927 N/A ALA 108.A N GLU 104.A O no hydrogen 2.923 N/A THR 109.A N GLN 105.A O no hydrogen 3.103 N/A THR 109.A OG1 GLN 105.A O no hydrogen 2.819 N/A THR 109.A OG1 SER 261.A OG no hydrogen 2.831 N/A TYR 110.A N ARG 106.A O no hydrogen 3.039 N/A ILE 111.A N THR 107.A O no hydrogen 2.894 N/A THR 112.A N ALA 108.A O no hydrogen 2.973 N/A THR 112.A OG1 ALA 108.A O no hydrogen 3.003 N/A THR 112.A OG1 SER 260.A OG no hydrogen 3.021 N/A GLU 113.A N THR 109.A O no hydrogen 3.094 N/A LEU 114.A N TYR 110.A O no hydrogen 2.972 N/A ALA 115.A N ILE 111.A O no hydrogen 2.810 N/A ASN 116.A N THR 112.A O no hydrogen 2.900 N/A ASN 116.A ND2 PRO 263.A O no hydrogen 3.090 N/A ALA 117.A N GLU 113.A O no hydrogen 3.140 N/A LEU 118.A N LEU 114.A O no hydrogen 2.881 N/A SER 119.A N ALA 115.A O no hydrogen 2.869 N/A TYR 120.A N ASN 116.A O no hydrogen 3.193 N/A CYS 121.A N ALA 117.A O no hydrogen 3.037 N/A CYS 121.A SG ALA 117.A O no hydrogen 3.467 N/A HIS 122.A N LEU 118.A O no hydrogen 2.796 N/A HIS 122.A NE2 ASP 184.A OD2 no hydrogen 2.903 N/A SER 123.A N SER 119.A O no hydrogen 3.084 N/A SER 123.A OG TYR 120.A O no hydrogen 2.604 N/A LYS 124.A N CYS 121.A O no hydrogen 2.935 N/A ARG 125.A N HIS 122.A O no hydrogen 2.777 N/A ARG 125.A NE GLU 181.A OE2 no hydrogen 2.977 N/A ARG 125.A NH2 GLU 181.A OE1 no hydrogen 3.108 N/A ARG 125.A NH2 GLU 181.A OE2 no hydrogen 3.367 N/A VAL 126.A N CYS 121.A O no hydrogen 3.031 N/A ILE 127.A N VAL 153.A O no hydrogen 2.960 N/A HIS 128.A N ASP 184.A OD2 no hydrogen 3.017 N/A HIS 128.A NE2 ALA 147.A O no hydrogen 2.992 N/A ARG 129.A N ASP 184.A OD1 no hydrogen 3.008 N/A ARG 129.A NE TRP 151.A O no hydrogen 2.805 N/A ARG 129.A NH1 HIS 179.A NE2 no hydrogen 2.891 N/A ARG 129.A NH2 TRP 151.A O no hydrogen 3.077 N/A ASP 130.A N HIS 128.A ND1 no hydrogen 3.110 N/A LYS 132.A NZ ASP 130.A OD1 no hydrogen 2.991 N/A GLU 134.A N GLU 134.A OE2 no hydrogen 3.053 N/A ASN 135.A N LYS 132.A O no hydrogen 2.878 N/A ASN 135.A ND2 ASP 130.A O no hydrogen 3.081 N/A LEU 136.A N PRO 133.A O no hydrogen 3.058 N/A LEU 137.A N LYS 145.A O no hydrogen 2.784 N/A LEU 138.A N GLY 90.A O no hydrogen 2.767 N/A GLY 139.A N GLU 143.A O no hydrogen 2.885 N/A ALA 141.A N GLU 143.A OE1 no hydrogen 3.075 N/A GLY 142.A N GLY 139.A O no hydrogen 2.928 N/A GLU 143.A N GLU 143.A OE1 no hydrogen 2.646 N/A LEU 144.A N GLU 113.A OE1 no hydrogen 3.444 N/A LEU 144.A N GLU 113.A OE2 no hydrogen 3.248 N/A LYS 145.A N LEU 137.A O no hydrogen 2.716 N/A LYS 145.A NZ PRO 65.A O no hydrogen 2.975 N/A LYS 145.A NZ GLU 85.A OE2 no hydrogen 3.178 N/A ILE 146.A N ASN 66.A O no hydrogen 2.955 N/A ALA 147.A N ASN 135.A O no hydrogen 3.043 N/A SER 152.A N PHE 149.A O no hydrogen 3.127 N/A SER 152.A OG PHE 149.A O no hydrogen 3.019 N/A VAL 153.A N ILE 127.A O no hydrogen 3.070 N/A ALA 155.A N ARG 125.A O no hydrogen 3.378 N/A SER 157.A OG SER 158.A O no hydrogen 2.998 N/A ARG 159.A NH1 THR 161.A O no hydrogen 2.793 N/A THR 161.A OG1 HIS 50.A NE2 no hydrogen 3.317 N/A THR 165.A OG1 ASP 167.A OD2 no hydrogen 2.697 N/A ASP 167.A N THR 165.A OG1 no hydrogen 3.050 N/A TYR 168.A OH GLU 194.A OE1 no hydrogen 2.578 N/A LEU 169.A N LEU 166.A O no hydrogen 2.991 N/A GLU 172.A N GLU 172.A OE1 no hydrogen 2.624 N/A MET 173.A N PRO 170.A O no hydrogen 3.080 N/A ILE 174.A N PRO 170.A O no hydrogen 3.239 N/A GLU 175.A N PRO 171.A O no hydrogen 2.929 N/A GLY 176.A N MET 173.A O no hydrogen 3.230 N/A ARG 177.A NH1 GLU 175.A OE1 no hydrogen 2.524 N/A HIS 179.A N SER 157.A O no hydrogen 2.970 N/A GLU 181.A N GLU 181.A OE1 no hydrogen 2.782 N/A LYS 182.A N ASP 180.A OD1 no hydrogen 3.151 N/A LYS 182.A NZ ARG 244.A O no hydrogen 2.806 N/A LYS 182.A NZ PRO 245.A O no hydrogen 3.261 N/A VAL 183.A N ASP 180.A O no hydrogen 3.274 N/A ASP 184.A N GLU 181.A O no hydrogen 3.028 N/A TRP 186.A N LYS 182.A O no hydrogen 3.104 N/A SER 187.A N VAL 183.A O no hydrogen 3.151 N/A SER 187.A OG TYR 168.A O no hydrogen 2.878 N/A SER 187.A OG VAL 183.A O no hydrogen 3.313 N/A LEU 188.A N ASP 184.A O no hydrogen 3.008 N/A GLY 189.A N LEU 185.A O no hydrogen 3.235 N/A VAL 190.A N TRP 186.A O no hydrogen 3.065 N/A LEU 191.A N SER 187.A O no hydrogen 2.990 N/A CYS 192.A N LEU 188.A O no hydrogen 2.979 N/A TYR 193.A N GLY 189.A O no hydrogen 3.117 N/A TYR 193.A OH THR 220.A O no hydrogen 2.603 N/A GLU 194.A N VAL 190.A O no hydrogen 3.025 N/A PHE 195.A N LEU 191.A O no hydrogen 2.795 N/A LEU 196.A N CYS 192.A O no hydrogen 3.333 N/A VAL 197.A N TYR 193.A O no hydrogen 2.970 N/A GLY 198.A N GLU 194.A O no hydrogen 2.787 N/A GLU 203.A N PRO 200.A O no hydrogen 3.327 N/A GLN 208.A N GLN 208.A OE1 no hydrogen 2.736 N/A GLU 209.A N THR 206.A OG1 no hydrogen 2.849 N/A THR 210.A N THR 206.A O no hydrogen 3.098 N/A THR 210.A OG1 THR 206.A O no hydrogen 2.977 N/A TYR 211.A N TYR 207.A O no hydrogen 2.984 N/A LYS 212.A N GLN 208.A O no hydrogen 3.212 N/A ARG 213.A N GLU 209.A O no hydrogen 3.052 N/A ILE 214.A N THR 210.A O no hydrogen 2.998 N/A SER 215.A N TYR 211.A O no hydrogen 3.046 N/A SER 215.A OG TYR 211.A O no hydrogen 3.054 N/A SER 215.A OG LYS 212.A O no hydrogen 3.023 N/A ARG 216.A N LYS 212.A O no hydrogen 3.069 N/A VAL 217.A N ILE 214.A O no hydrogen 3.117 N/A GLU 218.A N ARG 213.A O no hydrogen 2.807 N/A VAL 225.A N PRO 222.A O no hydrogen 3.267 N/A THR 226.A OG1 GLU 104.A OE2 no hydrogen 2.552 N/A ARG 230.A N THR 226.A O no hydrogen 3.040 N/A ARG 230.A NE VAL 225.A O no hydrogen 2.974 N/A ASP 231.A N GLU 227.A O no hydrogen 3.003 N/A LEU 232.A N GLY 228.A O no hydrogen 3.142 N/A ILE 233.A N ALA 229.A O no hydrogen 2.898 N/A SER 234.A N ARG 230.A O no hydrogen 2.923 N/A SER 234.A OG ARG 230.A O no hydrogen 3.026 N/A ARG 235.A N ASP 231.A O no hydrogen 3.237 N/A ARG 235.A NE ASP 231.A OD2 no hydrogen 2.940 N/A ARG 235.A NH2 ASP 231.A OD2 no hydrogen 3.387 N/A LEU 236.A N LEU 232.A O no hydrogen 3.228 N/A LEU 237.A N ILE 233.A O no hydrogen 3.112 N/A SER 242.A N ASN 240.A OD1 no hydrogen 3.184 N/A SER 242.A OG ASN 240.A OD1 no hydrogen 2.703 N/A GLN 243.A N ASN 240.A O no hydrogen 2.912 N/A ARG 244.A N PRO 241.A O no hydrogen 3.165 N/A ARG 244.A NE LYS 238.A O no hydrogen 2.891 N/A ARG 244.A NH1 GLU 172.A OE2 no hydrogen 2.894 N/A ARG 244.A NH1 LYS 182.A O no hydrogen 2.965 N/A ARG 244.A NH2 GLU 172.A OE1 no hydrogen 3.070 N/A ARG 244.A NH2 GLU 172.A OE2 no hydrogen 3.413 N/A ARG 244.A NH2 LYS 238.A O no hydrogen 3.098 N/A ARG 244.A NH2 HIS 239.A O no hydrogen 3.271 N/A MET 246.A N GLU 249.A OE2 no hydrogen 2.999 N/A VAL 250.A N MET 246.A O no hydrogen 3.276 N/A LEU 251.A N LEU 247.A O no hydrogen 3.030 N/A GLU 252.A N ARG 248.A O no hydrogen 3.052 N/A HIS 253.A N VAL 250.A O no hydrogen 3.182 N/A HIS 253.A NE2 ASP 231.A OD2 no hydrogen 2.699 N/A TRP 255.A N HIS 253.A ND1 no hydrogen 3.074 N/A TRP 255.A NE1 GLU 104.A OE2 no hydrogen 2.795 N/A THR 257.A N HIS 253.A O no hydrogen 2.985 N/A THR 257.A OG1 PRO 254.A O no hydrogen 3.062 N/A ALA 258.A N PRO 254.A O no hydrogen 2.937 N/A ASN 259.A N TRP 255.A O no hydrogen 3.240 N/A ASN 259.A N ILE 256.A O no hydrogen 3.103 N/A ASN 259.A ND2 TRP 255.A O no hydrogen 3.035 N/A SER 260.A N ILE 256.A O no hydrogen 2.759 N/A SER 260.A OG THR 112.A OG1 no hydrogen 3.021 N/A SER 260.A OG LYS 262.A O no hydrogen 3.148 N/A SER 261.A N THR 109.A OG1 no hydrogen 3.105 N/A SER 261.A OG THR 109.A OG1 no hydrogen 2.831 N/A LYS 262.A N SER 260.A OG no hydrogen 3.225 N/A