Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6rfo_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 7.A N TYR 83.A OH no hydrogen 3.148 N/A ARG 11.A NE ASP 25.A OD1 no hydrogen 3.080 N/A ARG 11.A NH2 ASP 25.A OD2 no hydrogen 3.102 N/A TYR 12.A OH ASP 69.A OD2 no hydrogen 2.842 N/A THR 13.A N TYR 24.A O no hydrogen 2.688 N/A THR 13.A OG1 TYR 24.A O no hydrogen 3.260 N/A SER 16.A N SER 22.A O no hydrogen 3.028 N/A SER 16.A OG SER 22.A OG no hydrogen 3.274 N/A CYS 21.A N ILE 34.A O no hydrogen 2.823 N/A SER 22.A N SER 16.A O no hydrogen 2.990 N/A SER 22.A OG SER 16.A O no hydrogen 3.124 N/A ALA 23.A N VAL 32.A O no hydrogen 2.969 N/A ASP 25.A N VAL 30.A O no hydrogen 3.006 N/A ASN 26.A N ARG 11.A O no hydrogen 2.618 N/A ASN 26.A ND2 PRO 10.A O no hydrogen 3.546 N/A ASN 26.A ND2 ARG 11.A O no hydrogen 3.132 N/A LEU 27.A N ASP 25.A OD1 no hydrogen 2.945 N/A VAL 32.A N ALA 23.A O no hydrogen 2.729 N/A ALA 33.A N GLN 86.A O no hydrogen 2.891 N/A ILE 34.A N CYS 21.A O no hydrogen 2.755 N/A LYS 35.A N ILE 84.A O no hydrogen 2.814 N/A LYS 35.A NZ GLN 86.A OE1 no hydrogen 2.959 N/A LYS 36.A N MET 19.A O no hydrogen 2.868 N/A LYS 36.A NZ VAL 5.A O no hydrogen 2.771 N/A ILE 37.A N VAL 82.A O no hydrogen 2.819 N/A SER 38.A OG ASP 81.A OD1 no hydrogen 2.719 N/A HIS 42.A N PRO 39.A O no hydrogen 3.265 N/A CYS 46.A N HIS 42.A O no hydrogen 2.922 N/A CYS 46.A SG PRO 39.A O no hydrogen 3.255 N/A CYS 46.A SG HIS 42.A O no hydrogen 3.714 N/A GLN 47.A N GLN 43.A O no hydrogen 3.028 N/A ARG 48.A N THR 44.A O no hydrogen 3.038 N/A THR 49.A N TYR 45.A O no hydrogen 2.892 N/A THR 49.A OG1 TYR 45.A O no hydrogen 2.799 N/A LEU 50.A N CYS 46.A O no hydrogen 2.857 N/A ARG 51.A N GLN 47.A O no hydrogen 2.881 N/A ARG 51.A NE GLY 150.A O no hydrogen 3.097 N/A ARG 51.A NH2 GLY 150.A O no hydrogen 2.767 N/A GLU 52.A N ARG 48.A O no hydrogen 2.881 N/A ILE 53.A N THR 49.A O no hydrogen 2.940 N/A LYS 54.A N LEU 50.A O no hydrogen 2.774 N/A ILE 55.A N ARG 51.A O no hydrogen 2.894 N/A LEU 56.A N GLU 52.A O no hydrogen 2.864 N/A LEU 57.A N ILE 53.A O no hydrogen 2.957 N/A ARG 58.A N ILE 55.A O no hydrogen 3.077 N/A ARG 58.A NH2 ALA 293.A O no hydrogen 2.814 N/A ARG 58.A NH2 PRO 294.A O no hydrogen 3.354 N/A PHE 59.A N ILE 55.A O no hydrogen 3.093 N/A ARG 60.A N TYR 120.A OH no hydrogen 3.113 N/A ASN 63.A ND2 LEU 144.A O no hydrogen 2.981 N/A ILE 64.A N HIS 61.A O no hydrogen 3.143 N/A ILE 65.A N ILE 146.A O no hydrogen 2.986 N/A ASN 68.A N VAL 85.A O no hydrogen 2.751 N/A ASP 69.A N VAL 85.A O no hydrogen 3.370 N/A ILE 71.A N TYR 83.A O no hydrogen 2.829 N/A ARG 72.A NE ALA 73.A O no hydrogen 3.195 N/A ARG 72.A NH1 PHE 307.A O no hydrogen 2.916 N/A ARG 72.A NH1 THR 310.A OG1 no hydrogen 3.274 N/A ARG 72.A NH2 ALA 73.A O no hydrogen 2.868 N/A THR 75.A OG1 GLN 78.A OE1 no hydrogen 2.634 N/A GLU 77.A N GLU 77.A OE1 no hydrogen 2.916 N/A GLN 78.A N THR 75.A O no hydrogen 3.204 N/A GLN 78.A N THR 75.A OG1 no hydrogen 3.203 N/A MET 79.A N ILE 76.A O no hydrogen 3.076 N/A VAL 82.A N ILE 37.A O no hydrogen 2.851 N/A TYR 83.A N ILE 71.A O no hydrogen 2.749 N/A ILE 84.A N LYS 35.A O no hydrogen 2.846 N/A VAL 85.A N ASP 69.A O no hydrogen 2.965 N/A GLN 86.A N ALA 33.A O no hydrogen 2.908 N/A GLN 86.A NE2 GLY 66.A O no hydrogen 3.536 N/A THR 91.A N LEU 138.A O no hydrogen 2.894 N/A THR 91.A OG1 ASP 92.A O no hydrogen 3.379 N/A LEU 93.A N LEU 136.A O no hydrogen 2.805 N/A LYS 95.A N ASP 92.A OD1 no hydrogen 2.959 N/A LEU 96.A N ASP 92.A O no hydrogen 3.004 N/A LEU 97.A N LEU 93.A O no hydrogen 2.824 N/A LYS 98.A N TYR 94.A O no hydrogen 3.202 N/A LYS 98.A N LYS 95.A O no hydrogen 3.237 N/A THR 99.A N LEU 96.A O no hydrogen 3.237 N/A GLN 100.A N LEU 96.A O no hydrogen 2.795 N/A GLN 100.A NE2 THR 99.A OG1 no hydrogen 3.314 N/A SER 103.A OG HIS 106.A ND1 no hydrogen 2.727 N/A HIS 106.A N SER 103.A OG no hydrogen 2.942 N/A HIS 106.A ND1 SER 103.A OG no hydrogen 2.727 N/A ILE 107.A N SER 103.A O no hydrogen 2.892 N/A CYS 108.A N ASN 104.A O no hydrogen 3.011 N/A CYS 108.A SG TYR 278.A O no hydrogen 3.239 N/A CYS 108.A SG GLN 281.A OE1 no hydrogen 4.008 N/A TYR 109.A N ASP 105.A O no hydrogen 3.034 N/A PHE 110.A N HIS 106.A O no hydrogen 2.787 N/A LEU 111.A N ILE 107.A O no hydrogen 2.869 N/A TYR 112.A N CYS 108.A O no hydrogen 2.936 N/A TYR 112.A OH GLU 288.A OE2 no hydrogen 2.489 N/A GLN 113.A N TYR 109.A O no hydrogen 3.044 N/A GLN 113.A NE2 TYR 109.A O no hydrogen 3.463 N/A GLN 113.A NE2 CYS 142.A O no hydrogen 3.091 N/A ILE 114.A N PHE 110.A O no hydrogen 2.991 N/A LEU 115.A N LEU 111.A O no hydrogen 3.019 N/A ARG 116.A N TYR 112.A O no hydrogen 2.861 N/A ARG 116.A NE ASP 287.A O no hydrogen 2.798 N/A ARG 116.A NH1 GLU 62.A OE1 no hydrogen 2.963 N/A ARG 116.A NH1 ASN 63.A OD1 no hydrogen 2.941 N/A ARG 116.A NH2 GLU 62.A OE1 no hydrogen 3.201 N/A ARG 116.A NH2 ASP 287.A O no hydrogen 2.874 N/A ARG 116.A NH2 ASP 287.A OD1 no hydrogen 3.492 N/A GLY 117.A N GLN 113.A O no hydrogen 2.984 N/A LEU 118.A N ILE 114.A O no hydrogen 2.867 N/A LYS 119.A N LEU 115.A O no hydrogen 2.822 N/A LYS 119.A NZ GLU 288.A O no hydrogen 2.717 N/A ILE 121.A N GLY 117.A O no hydrogen 2.968 N/A HIS 122.A N LEU 118.A O no hydrogen 2.879 N/A HIS 122.A NE2 ASP 176.A OD2 no hydrogen 2.637 N/A SER 123.A N LYS 119.A O no hydrogen 2.910 N/A SER 123.A OG LYS 119.A O no hydrogen 3.500 N/A SER 123.A OG TYR 120.A O no hydrogen 2.450 N/A ALA 124.A N ILE 121.A O no hydrogen 2.993 N/A ASN 125.A N HIS 122.A O no hydrogen 2.919 N/A ASN 125.A ND2 PHE 295.A O no hydrogen 3.018 N/A VAL 126.A N ILE 121.A O no hydrogen 3.245 N/A LEU 127.A N ARG 153.A O no hydrogen 2.874 N/A HIS 128.A N ASP 176.A OD2 no hydrogen 2.967 N/A HIS 128.A NE2 LEU 147.A O no hydrogen 2.948 N/A ARG 129.A N ASP 176.A OD1 no hydrogen 2.835 N/A ARG 129.A NE LEU 151.A O no hydrogen 2.605 N/A ARG 129.A NH2 LEU 151.A O no hydrogen 2.710 N/A ASP 130.A N HIS 128.A ND1 no hydrogen 2.997 N/A LYS 132.A NZ THR 159.A OG1 no hydrogen 3.018 N/A ASN 135.A N LYS 132.A O no hydrogen 2.883 N/A LEU 136.A N PRO 133.A O no hydrogen 2.939 N/A LEU 137.A N LYS 145.A O no hydrogen 2.824 N/A LEU 138.A N THR 91.A O no hydrogen 2.951 N/A ASN 139.A N ASP 143.A O no hydrogen 3.193 N/A ASN 139.A ND2 ASP 143.A OD2 no hydrogen 2.844 N/A THR 141.A N ASN 139.A OD1 no hydrogen 3.152 N/A THR 141.A OG1 ASN 139.A OD1 no hydrogen 3.237 N/A THR 141.A OG1 ASP 143.A OD2 no hydrogen 2.841 N/A CYS 142.A N ASN 139.A O no hydrogen 3.051 N/A ASP 143.A N ASN 139.A OD1 no hydrogen 2.852 N/A LEU 144.A N GLN 113.A OE1 no hydrogen 2.735 N/A LYS 145.A N LEU 137.A O no hydrogen 2.759 N/A LYS 145.A NZ GLU 62.A O no hydrogen 2.702 N/A ILE 146.A N ASN 63.A O no hydrogen 2.778 N/A LEU 147.A N ASN 135.A O no hydrogen 2.863 N/A PHE 149.A N GLU 52.A OE2 no hydrogen 3.059 N/A GLY 150.A N ASP 148.A OD1 no hydrogen 3.213 N/A ALA 152.A N PHE 149.A O no hydrogen 3.227 N/A ARG 153.A N LEU 127.A O no hydrogen 3.187 N/A ARG 153.A NH1 LEU 151.A O no hydrogen 3.168 N/A ARG 153.A NH1 ALA 152.A O no hydrogen 3.108 N/A HIS 154.A NE2 PHE 295.A O no hydrogen 2.755 N/A THR 155.A N ASN 125.A O no hydrogen 2.966 N/A THR 155.A OG1 ASN 125.A O no hydrogen 3.217 N/A ASP 156.A N HIS 154.A ND1 no hydrogen 2.935 N/A ASP 157.A N HIS 154.A O no hydrogen 3.012 N/A THR 159.A OG1 ASP 130.A OD1 no hydrogen 2.508 N/A THR 159.A OG1 ASP 130.A OD2 no hydrogen 3.549 N/A ARG 160.A NH1 GLY 196.A O no hydrogen 2.967 N/A TRP 161.A NE1 GLY 196.A O no hydrogen 2.944 N/A TYR 162.A N THR 159.A O no hydrogen 3.302 N/A TYR 162.A OH GLU 186.A OE1 no hydrogen 2.455 N/A TYR 162.A OH GLU 186.A OE2 no hydrogen 3.383 N/A ARG 163.A N ARG 160.A O no hydrogen 3.080 N/A ARG 163.A NE ALA 158.A O no hydrogen 3.084 N/A ARG 163.A NH2 ALA 158.A O no hydrogen 2.755 N/A GLU 166.A N GLU 166.A OE1 no hydrogen 2.713 N/A ILE 167.A N ALA 164.A O no hydrogen 3.042 N/A MET 168.A N PRO 165.A O no hydrogen 2.849 N/A LEU 169.A N GLU 166.A O no hydrogen 3.191 N/A ASN 170.A ND2 ASN 170.A O no hydrogen 2.765 N/A LYS 173.A NZ HIS 122.A O no hydrogen 3.174 N/A SER 174.A N THR 172.A OG1 no hydrogen 3.240 N/A SER 174.A OG PRO 264.A O no hydrogen 3.193 N/A ILE 175.A N THR 172.A O no hydrogen 2.967 N/A ASP 176.A N LYS 173.A O no hydrogen 2.990 N/A TRP 178.A N SER 174.A O no hydrogen 3.262 N/A SER 179.A N ILE 175.A O no hydrogen 3.313 N/A SER 179.A OG TYR 162.A O no hydrogen 2.691 N/A SER 179.A OG ILE 175.A O no hydrogen 3.439 N/A VAL 180.A N ASP 176.A O no hydrogen 2.991 N/A GLY 181.A N ILE 177.A O no hydrogen 2.836 N/A CYS 182.A N TRP 178.A O no hydrogen 2.811 N/A CYS 182.A SG TRP 161.A O no hydrogen 3.846 N/A CYS 182.A SG TRP 178.A O no hydrogen 3.482 N/A ILE 183.A N SER 179.A O no hydrogen 2.942 N/A LEU 184.A N VAL 180.A O no hydrogen 2.766 N/A ALA 185.A N GLY 181.A O no hydrogen 3.053 N/A GLU 186.A N CYS 182.A O no hydrogen 3.046 N/A MET 187.A N ILE 183.A O no hydrogen 2.837 N/A LEU 188.A N LEU 184.A O no hydrogen 2.957 N/A LEU 188.A N ALA 185.A O no hydrogen 3.134 N/A SER 189.A N GLU 186.A O no hydrogen 3.381 N/A SER 189.A OG ALA 185.A O no hydrogen 3.150 N/A SER 189.A OG ARG 191.A O no hydrogen 3.280 N/A ASN 190.A N GLU 186.A O no hydrogen 2.730 N/A ASN 190.A ND2 LEU 97.A O no hydrogen 2.793 N/A ASN 190.A ND2 GLN 100.A O no hydrogen 2.802 N/A ARG 191.A N SER 189.A OG no hydrogen 3.379 N/A ARG 191.A NH1 PRO 192.A O no hydrogen 2.621 N/A GLY 196.A N PHE 194.A O no hydrogen 2.944 N/A LYS 197.A N ASP 201.A OD2 no hydrogen 2.803 N/A GLN 202.A N HIS 198.A O no hydrogen 3.197 N/A GLN 202.A N TYR 199.A O no hydrogen 3.201 N/A GLN 202.A NE2 PHE 194.A O no hydrogen 2.835 N/A ASN 204.A N LEU 200.A O no hydrogen 3.192 N/A HIS 205.A N ASP 201.A O no hydrogen 2.895 N/A HIS 205.A ND1 ASP 201.A O no hydrogen 3.066 N/A ILE 206.A N GLN 202.A O no hydrogen 2.924 N/A LEU 207.A N LEU 203.A O no hydrogen 2.948 N/A GLY 208.A N ASN 204.A O no hydrogen 2.755 N/A ILE 209.A N ILE 206.A O no hydrogen 3.099 N/A LEU 210.A N ILE 206.A O no hydrogen 2.854 N/A GLY 211.A N LEU 207.A O no hydrogen 2.805 N/A SER 212.A N LYS 236.A O no hydrogen 2.889 N/A SER 212.A OG LYS 236.A O no hydrogen 3.340 N/A ASP 217.A N SER 214.A OG no hydrogen 2.998 N/A LEU 218.A N SER 214.A O no hydrogen 2.936 N/A ASN 219.A N GLN 215.A O no hydrogen 2.845 N/A CYS 220.A N ASP 217.A O no hydrogen 3.233 N/A CYS 220.A SG GLU 216.A O no hydrogen 3.476 N/A ILE 221.A N LEU 218.A O no hydrogen 2.845 N/A ARG 227.A N ASN 223.A O no hydrogen 2.884 N/A ARG 227.A NE ILE 221.A O no hydrogen 2.786 N/A ARG 227.A NH2 ILE 221.A O no hydrogen 2.854 N/A ASN 228.A N LEU 224.A O no hydrogen 2.805 N/A TYR 229.A N LYS 225.A O no hydrogen 2.994 N/A LEU 230.A N ALA 226.A O no hydrogen 3.055 N/A LEU 231.A N ARG 227.A O no hydrogen 2.893 N/A SER 232.A N ASN 228.A O no hydrogen 2.899 N/A SER 232.A N TYR 229.A O no hydrogen 3.121 N/A SER 232.A OG TYR 229.A O no hydrogen 2.597 N/A LEU 233.A N LEU 230.A O no hydrogen 3.238 N/A LYS 236.A N SER 212.A OG no hydrogen 2.835 N/A LYS 238.A NZ ASP 257.A OD1 no hydrogen 3.332 N/A VAL 239.A N ILE 209.A O no hydrogen 2.823 N/A TRP 241.A NE1 ASP 257.A OD1 no hydrogen 2.888 N/A ARG 243.A N PRO 240.A O no hydrogen 2.897 N/A LEU 244.A N PRO 240.A O no hydrogen 3.329 N/A PHE 245.A N TRP 241.A O no hydrogen 2.767 N/A ALA 248.A N PHE 245.A O no hydrogen 3.130 N/A LYS 251.A N ASP 249.A OD1 no hydrogen 2.878 N/A LEU 253.A N ASP 249.A O no hydrogen 3.199 N/A ASP 254.A N SER 250.A O no hydrogen 2.907 N/A LEU 255.A N LYS 251.A O no hydrogen 3.038 N/A LEU 256.A N ALA 252.A O no hydrogen 2.823 N/A ASP 257.A N LEU 253.A O no hydrogen 2.866 N/A LYS 258.A N ASP 254.A O no hydrogen 3.199 N/A LYS 258.A NZ ASP 254.A OD1 no hydrogen 3.351 N/A LYS 258.A NZ ASP 254.A OD2 no hydrogen 2.917 N/A MET 259.A N LEU 255.A O no hydrogen 2.997 N/A LEU 260.A N LEU 256.A O no hydrogen 2.738 N/A THR 261.A OG1 ASP 257.A O no hydrogen 2.924 N/A THR 261.A OG1 LYS 258.A O no hydrogen 3.244 N/A ASN 263.A ND2 ASP 217.A OD1 no hydrogen 2.996 N/A HIS 265.A N ASN 263.A OD1 no hydrogen 2.981 N/A LYS 266.A N ASN 263.A O no hydrogen 2.955 N/A LYS 266.A NZ GLU 216.A OE2 no hydrogen 3.024 N/A LYS 266.A NZ ASP 217.A OD1 no hydrogen 2.610 N/A ARG 267.A N PRO 264.A O no hydrogen 3.326 N/A ARG 267.A NE THR 261.A O no hydrogen 2.958 N/A ARG 267.A NH1 GLU 166.A OE1 no hydrogen 3.455 N/A ARG 267.A NH1 GLU 166.A OE2 no hydrogen 2.658 N/A ARG 267.A NH1 SER 174.A O no hydrogen 2.891 N/A ARG 267.A NH2 GLU 166.A OE1 no hydrogen 2.892 N/A ARG 267.A NH2 THR 261.A O no hydrogen 3.070 N/A ARG 267.A NH2 PHE 262.A O no hydrogen 3.136 N/A ILE 268.A N LYS 258.A O no hydrogen 3.073 N/A GLU 269.A N GLN 272.A OE1 no hydrogen 2.976 N/A GLU 271.A N GLU 271.A OE2 no hydrogen 2.707 N/A ALA 273.A N GLU 269.A O no hydrogen 2.816 N/A LEU 274.A N VAL 270.A O no hydrogen 2.941 N/A ALA 275.A N GLU 271.A O no hydrogen 3.244 N/A HIS 276.A N ALA 273.A O no hydrogen 3.043 N/A HIS 276.A NE2 ASP 254.A OD2 no hydrogen 2.701 N/A TYR 278.A N HIS 276.A ND1 no hydrogen 2.934 N/A LEU 279.A N HIS 276.A O no hydrogen 2.832 N/A GLU 280.A N PRO 277.A O no hydrogen 3.197 N/A TYR 282.A N LEU 279.A O no hydrogen 2.890 N/A TYR 283.A N LEU 279.A O no hydrogen 2.997 N/A ASP 284.A N GLU 288.A OE2 no hydrogen 2.927 N/A SER 286.A OG ASP 284.A OD1 no hydrogen 2.857 N/A ASP 287.A N ASP 284.A O no hydrogen 2.827 N/A GLU 288.A N PRO 285.A O no hydrogen 3.106 N/A ALA 291.A N SER 123.A OG no hydrogen 2.878 N/A PHE 295.A N ALA 124.A O no hydrogen 2.845 N/A GLU 300.A N GLU 300.A OE1 no hydrogen 2.709 N/A LEU 302.A N PRO 298.A O no hydrogen 3.178 N/A LYS 303.A N LYS 299.A O no hydrogen 2.789 N/A LYS 303.A NZ ILE 76.A O no hydrogen 2.893 N/A LYS 303.A NZ MET 79.A O no hydrogen 2.667 N/A GLU 304.A N GLU 300.A O no hydrogen 2.945 N/A LEU 305.A N LYS 301.A O no hydrogen 2.749 N/A ILE 306.A N LEU 302.A O no hydrogen 2.720 N/A PHE 307.A N LYS 303.A O no hydrogen 2.871 N/A GLU 308.A N GLU 304.A O no hydrogen 2.967 N/A GLU 309.A N LEU 305.A O no hydrogen 2.849 N/A THR 310.A N ILE 306.A O no hydrogen 3.089 N/A THR 310.A N PHE 307.A O no hydrogen 3.211 N/A THR 310.A OG1 ILE 306.A O no hydrogen 2.802 N/A THR 310.A OG1 PHE 307.A O no hydrogen 2.879 N/A ALA 311.A N GLU 308.A O no hydrogen 3.254 N/A PHE 313.A N THR 310.A O no hydrogen 3.344 N/A GLN 314.A N ALA 311.A O no hydrogen 2.997 N/A