Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6rxz_Cz.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N THR 1.A OG1 no hydrogen 3.235 N/A PHE 5.A N THR 1.A O no hydrogen 2.897 N/A GLU 6.A N ALA 2.A O no hydrogen 2.857 N/A ARG 7.A N SER 3.A O no hydrogen 2.913 N/A LEU 8.A N ASP 4.A O no hydrogen 2.953 N/A LEU 9.A N PHE 5.A O no hydrogen 2.840 N/A LEU 10.A N GLU 6.A O no hydrogen 2.909 N/A GLY 11.A N ARG 7.A O no hydrogen 2.975 N/A GLN 12.A N LEU 8.A O no hydrogen 2.853 N/A SER 15.A OG GLN 12.A O no hydrogen 3.004 N/A SER 15.A OG SER 15.A O no hydrogen 2.480 N/A SER 16.A N GLU 53.A OE1 no hydrogen 2.884 N/A SER 16.A OG GLU 53.A O no hydrogen 3.053 N/A GLU 17.A N GLU 17.A OE1 no hydrogen 2.680 N/A TRP 19.A N SER 15.A O no hydrogen 2.965 N/A TRP 19.A NE1 PRO 13.A O no hydrogen 2.675 N/A ILE 20.A N SER 16.A O no hydrogen 2.862 N/A ALA 21.A N GLU 17.A O no hydrogen 2.927 N/A TYR 22.A N LEU 18.A O no hydrogen 2.874 N/A TYR 22.A OH GLU 6.A OE1 no hydrogen 3.307 N/A MET 23.A N TRP 19.A O no hydrogen 2.962 N/A ALA 24.A N ILE 20.A O no hydrogen 2.770 N/A SER 25.A N ALA 21.A O no hydrogen 2.900 N/A SER 25.A OG ALA 21.A O no hydrogen 3.351 N/A SER 25.A OG TYR 22.A O no hydrogen 2.289 N/A GLN 26.A N TYR 22.A O no hydrogen 3.001 N/A MET 27.A N MET 23.A O no hydrogen 2.764 N/A GLN 28.A N ALA 24.A O no hydrogen 2.915 N/A VAL 29.A N SER 25.A O no hydrogen 2.853 N/A ASN 30.A N MET 27.A O no hydrogen 2.904 N/A LEU 32.A N ASN 30.A O no hydrogen 2.982 N/A SER 33.A OG ASP 31.A OD1 no hydrogen 2.510 N/A SER 34.A N ASP 31.A OD1 no hydrogen 2.990 N/A SER 34.A OG GLN 26.A OE1 no hydrogen 2.537 N/A SER 34.A OG ASP 31.A O no hydrogen 2.821 N/A ALA 35.A N ASP 31.A O no hydrogen 2.902 N/A ARG 36.A N LEU 32.A O no hydrogen 2.894 N/A GLN 37.A N SER 33.A O no hydrogen 2.903 N/A ILE 38.A N SER 34.A O no hydrogen 2.841 N/A ALA 39.A N ALA 35.A O no hydrogen 2.874 N/A GLU 40.A N ARG 36.A O no hydrogen 2.923 N/A ARG 41.A N GLN 37.A O no hydrogen 2.933 N/A ARG 41.A NE GLN 37.A OE1 no hydrogen 3.554 N/A ALA 42.A N ILE 38.A O no hydrogen 2.892 N/A LEU 43.A N ALA 39.A O no hydrogen 2.915 N/A LYS 44.A N GLU 40.A O no hydrogen 2.903 N/A LYS 44.A NZ GLU 40.A OE2 no hydrogen 3.039 N/A THR 45.A N ARG 41.A O no hydrogen 2.870 N/A THR 45.A OG1 ARG 41.A O no hydrogen 2.864 N/A ILE 46.A N ALA 42.A O no hydrogen 2.894 N/A ASN 47.A N ASP 14.A OD1 no hydrogen 2.548 N/A GLU 51.A N ARG 49.A O no hydrogen 2.999 N/A LYS 54.A N GLU 50.A O no hydrogen 2.978 N/A LYS 54.A NZ ASN 47.A O no hydrogen 3.300 N/A LYS 54.A NZ ILE 48.A O no hydrogen 2.443 N/A LYS 54.A NZ GLU 51.A OE2 no hydrogen 2.793 N/A LEU 55.A N GLU 51.A O no hydrogen 2.883 N/A ASN 56.A N THR 52.A O no hydrogen 2.934 N/A VAL 57.A N GLU 53.A O no hydrogen 3.015 N/A TRP 58.A N LYS 54.A O no hydrogen 2.877 N/A ILE 59.A N LEU 55.A O no hydrogen 2.848 N/A ALA 60.A N ASN 56.A O no hydrogen 2.982 N/A TYR 61.A N VAL 57.A O no hydrogen 2.972 N/A LEU 62.A N TRP 58.A O no hydrogen 2.907 N/A ASN 63.A N ILE 59.A O no hydrogen 2.929 N/A LEU 64.A N ALA 60.A O no hydrogen 2.984 N/A GLU 65.A N TYR 61.A O no hydrogen 2.943 N/A VAL 66.A N LEU 62.A O no hydrogen 2.952 N/A ALA 67.A N ASN 63.A O no hydrogen 2.937 N/A TYR 68.A N LEU 64.A O no hydrogen 2.882 N/A GLY 69.A N LEU 64.A O no hydrogen 3.071 N/A ASP 71.A N THR 70.A OG1 no hydrogen 2.475 N/A THR 73.A OG1 GLU 65.A OE1 no hydrogen 2.831 N/A THR 73.A OG1 GLU 76.A OE2 no hydrogen 3.025 N/A VAL 74.A N THR 70.A O no hydrogen 2.988 N/A GLN 75.A N ASP 71.A O no hydrogen 2.960 N/A GLU 76.A N GLU 72.A O no hydrogen 2.997 N/A VAL 77.A N THR 73.A O no hydrogen 2.974 N/A PHE 78.A N VAL 74.A O no hydrogen 2.897 N/A LYS 79.A N GLN 75.A O no hydrogen 2.926 N/A ARG 80.A N GLU 76.A O no hydrogen 2.926 N/A ALA 81.A N VAL 77.A O no hydrogen 2.805 N/A CYS 82.A N PHE 78.A O no hydrogen 2.976 N/A CYS 82.A SG PHE 78.A O no hydrogen 3.236 N/A CYS 82.A SG LYS 79.A O no hydrogen 3.125 N/A THR 83.A N LYS 79.A O no hydrogen 2.862 N/A THR 83.A OG1 LYS 79.A O no hydrogen 2.261 N/A TYR 84.A N ARG 80.A O no hydrogen 2.931 N/A ARG 88.A NH2 GLU 121.A OE1 no hydrogen 2.378 N/A VAL 90.A N ASP 86.A O no hydrogen 3.003 N/A HIS 91.A N ASP 87.A O no hydrogen 2.885 N/A HIS 91.A ND1 ASP 87.A O no hydrogen 2.323 N/A GLU 92.A N ARG 88.A O no hydrogen 2.916 N/A ARG 93.A N GLU 89.A O no hydrogen 2.882 N/A LEU 94.A N VAL 90.A O no hydrogen 2.926 N/A ALA 95.A N HIS 91.A O no hydrogen 2.899 N/A SER 96.A N GLU 92.A O no hydrogen 2.905 N/A ILE 97.A N ARG 93.A O no hydrogen 2.875 N/A TYR 98.A N LEU 94.A O no hydrogen 2.854 N/A ILE 99.A N ALA 95.A O no hydrogen 2.903 N/A GLN 100.A N SER 96.A O no hydrogen 2.894 N/A SER 101.A N ILE 97.A O no hydrogen 2.870 N/A SER 101.A OG ILE 97.A O no hydrogen 2.655 N/A SER 101.A OG TYR 98.A O no hydrogen 3.330 N/A LYS 103.A NZ SER 101.A OG no hydrogen 2.822 N/A TYR 104.A OH ILE 99.A O no hydrogen 3.168 N/A LYS 105.A NZ LYS 105.A O no hydrogen 2.696 N/A LYS 105.A NZ ASP 109.A OD1 no hydrogen 2.762 N/A LYS 105.A NZ ASP 109.A OD2 no hydrogen 3.259 N/A GLU 106.A N GLU 106.A OE2 no hydrogen 2.852 N/A ALA 107.A N LYS 103.A O no hydrogen 2.959 N/A GLU 108.A N TYR 104.A O no hydrogen 2.880 N/A ASP 109.A N LYS 105.A O no hydrogen 3.008 N/A LEU 110.A N GLU 106.A O no hydrogen 2.906 N/A PHE 111.A N ALA 107.A O no hydrogen 2.832 N/A GLU 112.A N GLU 108.A O no hydrogen 2.923 N/A LYS 113.A N ASP 109.A O no hydrogen 2.974 N/A LYS 113.A NZ LYS 113.A O no hydrogen 3.350 N/A ILE 114.A N LEU 110.A O no hydrogen 2.884 N/A VAL 115.A N PHE 111.A O no hydrogen 2.908 N/A LYS 116.A N GLU 112.A O no hydrogen 2.965 N/A LYS 117.A N LYS 113.A O no hydrogen 2.877 N/A LYS 117.A NZ ASP 87.A OD2 no hydrogen 3.002 N/A TYR 118.A N ILE 114.A O no hydrogen 2.857 N/A ALA 122.A N TYR 118.A O no hydrogen 3.125 N/A TRP 126.A NE1 GLY 119.A O no hydrogen 3.292 N/A TYR 127.A N PRO 123.A O no hydrogen 3.026 N/A ASN 128.A N HIS 124.A O no hydrogen 2.867 N/A TYR 129.A N VAL 125.A O no hydrogen 2.936 N/A TYR 129.A OH GLU 108.A OE2 no hydrogen 2.294 N/A ALA 130.A N TRP 126.A O no hydrogen 2.934 N/A HIS 131.A N TYR 127.A O no hydrogen 2.932 N/A PHE 132.A N ASN 128.A O no hydrogen 2.934 N/A LEU 133.A N TYR 129.A O no hydrogen 2.946 N/A HIS 134.A N ALA 130.A O no hydrogen 2.881 N/A HIS 134.A NE2 GLU 172.A OE2 no hydrogen 2.433 N/A THR 135.A N HIS 131.A O no hydrogen 2.894 N/A THR 135.A OG1 HIS 131.A O no hydrogen 2.519 N/A THR 135.A OG1 PHE 132.A O no hydrogen 2.883 N/A LYS 136.A NZ TYR 104.A OH no hydrogen 2.997 N/A SER 137.A N PHE 132.A O no hydrogen 3.457 N/A SER 137.A OG PHE 132.A O no hydrogen 3.512 N/A ASN 138.A N THR 135.A O no hydrogen 2.756 N/A LYS 139.A N LEU 133.A O no hydrogen 3.190 N/A LYS 139.A NZ SER 137.A O no hydrogen 2.843 N/A GLU 141.A N GLU 141.A OE2 no hydrogen 2.710 N/A ALA 143.A N LYS 139.A O no hydrogen 2.930 N/A ARG 144.A N PRO 140.A O no hydrogen 2.935 N/A ALA 145.A N GLU 141.A O no hydrogen 2.931 N/A LEU 146.A N GLN 142.A O no hydrogen 2.892 N/A LEU 147.A N ALA 143.A O no hydrogen 2.878 N/A LYS 148.A N ARG 144.A O no hydrogen 2.964 N/A ARG 149.A N ALA 145.A O no hydrogen 2.910 N/A ALA 150.A N LEU 146.A O no hydrogen 2.812 N/A THR 151.A N LEU 147.A O no hydrogen 2.938 N/A THR 151.A OG1 LYS 148.A O no hydrogen 2.610 N/A GLN 152.A N LYS 148.A O no hydrogen 2.960 N/A VAL 153.A N ARG 149.A O no hydrogen 2.857 N/A LEU 154.A N ALA 150.A O no hydrogen 2.899 N/A THR 157.A OG1 ASP 159.A OD1 no hydrogen 2.292 N/A THR 160.A N ASP 159.A OD1 no hydrogen 2.572 N/A TYR 161.A N THR 157.A O no hydrogen 3.000 N/A LEU 162.A N LYS 158.A O no hydrogen 2.895 N/A LEU 164.A N THR 160.A O no hydrogen 2.938 N/A LEU 165.A N TYR 161.A O no hydrogen 3.042 N/A LYS 167.A N TYR 163.A O no hydrogen 2.970 N/A LYS 167.A NZ TYR 163.A O no hydrogen 2.912 N/A PHE 168.A N LEU 164.A O no hydrogen 2.901 N/A ALA 169.A N LEU 165.A O no hydrogen 2.993 N/A ALA 170.A N PRO 166.A O no hydrogen 2.796 N/A LEU 171.A N LYS 167.A O no hydrogen 2.978 N/A GLU 172.A N PHE 168.A O no hydrogen 2.933 N/A PHE 173.A N ALA 169.A O no hydrogen 2.923 N/A ARG 174.A N ALA 170.A O no hydrogen 2.884 N/A SER 175.A N LEU 171.A O no hydrogen 2.950 N/A SER 175.A OG LEU 171.A O no hydrogen 2.397 N/A ASN 177.A ND2 HIS 134.A O no hydrogen 3.546 N/A GLY 178.A N SER 175.A O no hydrogen 2.893 N/A GLU 181.A N ASP 179.A OD1 no hydrogen 3.369 N/A GLN 182.A NE2 ASP 179.A OD2 no hydrogen 2.968 N/A GLY 183.A N ASP 179.A O no hydrogen 3.015 N/A ARG 184.A N ARG 180.A O no hydrogen 2.793 N/A THR 185.A N GLU 181.A O no hydrogen 2.930 N/A THR 185.A OG1 GLU 181.A O no hydrogen 2.706 N/A LEU 186.A N GLN 182.A O no hydrogen 2.968 N/A PHE 187.A N GLY 183.A O no hydrogen 2.914 N/A GLU 188.A N ARG 184.A O no hydrogen 2.834 N/A LYS 189.A N THR 185.A O no hydrogen 2.945 N/A LYS 189.A NZ GLU 188.A OE2 no hydrogen 3.302 N/A LEU 190.A N LEU 186.A O no hydrogen 2.927 N/A LEU 191.A N PHE 187.A O no hydrogen 2.940 N/A ALA 192.A N GLU 188.A O no hydrogen 2.883 N/A THR 193.A N LYS 189.A O no hydrogen 2.959 N/A TYR 194.A N LEU 190.A O no hydrogen 2.902 N/A TRP 201.A N ARG 197.A O no hydrogen 2.964 N/A TRP 201.A NE1 PRO 195.A O no hydrogen 2.866 N/A ASN 202.A N PHE 198.A O no hydrogen 2.823 N/A GLN 203.A N ASP 199.A O no hydrogen 2.878 N/A LEU 204.A N LEU 200.A O no hydrogen 2.947 N/A LEU 205.A N TRP 201.A O no hydrogen 2.933 N/A ASP 206.A N ASN 202.A O no hydrogen 2.850 N/A LEU 207.A N GLN 203.A O no hydrogen 2.953 N/A GLU 208.A N LEU 204.A O no hydrogen 2.938 N/A THR 209.A N LEU 205.A O no hydrogen 2.963 N/A SER 210.A N ASP 206.A O no hydrogen 2.925 N/A SER 210.A OG ASP 206.A O no hydrogen 2.629 N/A SER 210.A OG LEU 207.A O no hydrogen 3.035 N/A SER 212.A OG LEU 207.A O no hydrogen 2.818 N/A SER 212.A OG GLU 208.A O no hydrogen 3.369 N/A SER 213.A OG SER 213.A O no hydrogen 2.336 N/A LYS 216.A N SER 213.A O no hydrogen 3.040 N/A ASN 217.A N SER 213.A O no hydrogen 2.542 N/A SER 222.A OG ASP 220.A OD1 no hydrogen 2.892 N/A VAL 223.A N ASP 220.A OD1 no hydrogen 3.346 N/A ILE 224.A N ASP 220.A O no hydrogen 2.977 N/A ARG 225.A N PRO 221.A O no hydrogen 2.915 N/A ARG 225.A NE GLU 253.A OE2 no hydrogen 3.231 N/A ARG 225.A NH1 GLU 253.A OE2 no hydrogen 3.065 N/A ASP 226.A N SER 222.A O no hydrogen 2.956 N/A LEU 227.A N VAL 223.A O no hydrogen 2.904 N/A PHE 228.A N ILE 224.A O no hydrogen 2.966 N/A GLU 229.A N ARG 225.A O no hydrogen 2.905 N/A ARG 230.A N ASP 226.A O no hydrogen 2.949 N/A GLY 231.A N LEU 227.A O no hydrogen 2.867 N/A THR 232.A N PHE 228.A O no hydrogen 2.960 N/A THR 232.A OG1 GLU 229.A O no hydrogen 2.389 N/A LYS 233.A N GLU 229.A O no hydrogen 2.941 N/A VAL 234.A N ARG 230.A O no hydrogen 2.960 N/A ALA 242.A N ARG 238.A O no hydrogen 2.953 N/A LYS 243.A N PRO 239.A O no hydrogen 2.886 N/A LYS 243.A NZ PRO 239.A O no hydrogen 3.331 N/A ALA 244.A N ARG 240.A O no hydrogen 2.938 N/A TRP 245.A N GLN 241.A O no hydrogen 2.900 N/A PHE 246.A N ALA 242.A O no hydrogen 2.935 N/A ARG 247.A N LYS 243.A O no hydrogen 2.890 N/A ARG 248.A N ALA 244.A O no hydrogen 2.902 N/A TRP 249.A N TRP 245.A O no hydrogen 2.915 N/A ALA 250.A N PHE 246.A O no hydrogen 2.931 N/A GLN 251.A N ARG 247.A O no hydrogen 2.874 N/A TRP 252.A N ARG 248.A O no hydrogen 2.949 N/A GLU 253.A N TRP 249.A O no hydrogen 2.943 N/A GLU 254.A N ALA 250.A O no hydrogen 2.923 N/A LYS 255.A N GLN 251.A O no hydrogen 2.959 N/A PHE 256.A N TRP 252.A O no hydrogen 2.811 N/A GLY 257.A N GLU 253.A O no hydrogen 2.920 N/A SER 261.A OG GLU 253.A OE1 no hydrogen 2.439 N/A SER 261.A OG ASP 258.A O no hydrogen 2.598 N/A ARG 262.A N ASP 258.A O no hydrogen 2.971 N/A GLU 263.A N ALA 259.A O no hydrogen 2.914 N/A LYS 264.A N LYS 260.A O no hydrogen 2.934 N/A VAL 265.A N SER 261.A O no hydrogen 2.877 N/A SER 266.A N ARG 262.A O no hydrogen 2.982 N/A SER 266.A OG GLU 263.A O no hydrogen 2.569 N/A ALA 267.A N GLU 263.A O no hydrogen 2.923 N/A LYS 268.A N LYS 264.A O no hydrogen 2.894 N/A ALA 269.A N VAL 265.A O no hydrogen 2.898 N/A GLN 270.A N SER 266.A O no hydrogen 2.958 N/A GLU 271.A N ALA 267.A O no hydrogen 2.970 N/A TRP 272.A N LYS 268.A O no hydrogen 2.897 N/A ALA 273.A N ALA 269.A O no hydrogen 2.906 N/A ARG 274.A N GLN 270.A O no hydrogen 2.932 N/A