Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6soz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 1.A ND2 GLU 2.A O no hydrogen 2.911 N/A ASN 1.A ND2 ASN 231.A O no hydrogen 3.445 N/A ARG 3.A N GLY 192.A O no hydrogen 2.756 N/A ARG 3.A NH1 ASN 197.A OD1 no hydrogen 2.736 N/A ARG 3.A NH2 CYS 196.A O no hydrogen 2.853 N/A ASN 4.A N GLY 232.A O no hydrogen 3.137 N/A ASN 4.A ND2 GLY 190.A O no hydrogen 3.588 N/A ASN 4.A ND2 ASN 191.A O no hydrogen 2.784 N/A ALA 5.A N GLY 189.A O no hydrogen 2.784 N/A LEU 6.A N CYS 125.A O no hydrogen 3.060 N/A ASN 7.A N ILE 187.A O no hydrogen 2.797 N/A ALA 8.A N SER 127.A O no hydrogen 2.833 N/A ALA 11.A N ASN 7.A O no hydrogen 3.252 N/A ASN 12.A N ALA 8.A O no hydrogen 2.912 N/A ASN 12.A ND2 ALA 8.A O no hydrogen 2.896 N/A LYS 13.A N THR 9.A O no hydrogen 3.003 N/A LYS 13.A NZ SER 176.A O no hydrogen 3.048 N/A VAL 14.A N ALA 10.A O no hydrogen 3.071 N/A CYS 15.A N ALA 11.A O no hydrogen 2.897 N/A CYS 15.A SG ALA 11.A O no hydrogen 3.378 N/A GLY 16.A N ASN 12.A O no hydrogen 2.803 N/A LEU 17.A N LYS 13.A O no hydrogen 3.143 N/A SER 18.A N VAL 14.A O no hydrogen 3.089 N/A SER 18.A OG ALA 104.A O no hydrogen 2.862 N/A THR 19.A N CYS 15.A O no hydrogen 2.906 N/A TYR 20.A N GLY 16.A O no hydrogen 2.968 N/A TYR 20.A OH LEU 168.A O no hydrogen 2.643 N/A LEU 21.A N LEU 17.A O no hydrogen 2.930 N/A LYS 22.A N SER 18.A O no hydrogen 3.071 N/A LYS 22.A NZ GLU 108.A OE1 no hydrogen 3.361 N/A LYS 22.A NZ GLU 108.A OE2 no hydrogen 2.851 N/A LYS 22.A NZ TYR 153.A O no hydrogen 2.774 N/A GLY 23.A N THR 19.A O no hydrogen 3.102 N/A ILE 24.A N LEU 21.A O no hydrogen 3.298 N/A HIS 26.A N GLY 23.A O no hydrogen 2.868 N/A HIS 26.A NE2 ILE 155.A O no hydrogen 2.723 N/A ARG 27.A N GLY 23.A O no hydrogen 2.836 N/A ARG 27.A NH1 THR 166.A O no hydrogen 3.184 N/A ARG 27.A NH2 SER 163.A O no hydrogen 2.766 N/A ARG 27.A NH2 THR 166.A O no hydrogen 3.178 N/A ARG 27.A NH2 THR 166.A OG1 no hydrogen 2.929 N/A VAL 28.A N ILE 24.A O no hydrogen 2.874 N/A ASN 29.A N ALA 25.A O no hydrogen 3.403 N/A SER 30.A N HIS 26.A O no hydrogen 3.034 N/A SER 30.A OG HIS 26.A O no hydrogen 3.384 N/A GLU 31.A N ARG 27.A O no hydrogen 3.052 N/A SER 32.A N VAL 28.A O no hydrogen 2.937 N/A SER 32.A OG VAL 28.A O no hydrogen 2.772 N/A ALA 33.A N ASN 29.A O no hydrogen 3.018 N/A VAL 34.A N SER 30.A O no hydrogen 3.137 N/A THR 36.A N SER 32.A O no hydrogen 3.193 N/A THR 36.A OG1 ALA 33.A O no hydrogen 3.392 N/A GLU 37.A N ALA 33.A O no hydrogen 3.265 N/A LYS 38.A N VAL 34.A O no hydrogen 3.257 N/A LEU 39.A N VAL 35.A O no hydrogen 2.795 N/A SER 40.A N THR 36.A O no hydrogen 3.041 N/A ASP 41.A N GLU 37.A O no hydrogen 3.046 N/A LEU 42.A N LYS 38.A O no hydrogen 3.148 N/A LYS 43.A N LEU 39.A O no hydrogen 3.116 N/A LYS 43.A NZ GLN 83.A OE1 no hydrogen 3.076 N/A MET 44.A N SER 40.A O no hydrogen 2.965 N/A ARG 45.A N ASP 41.A O no hydrogen 3.056 N/A SER 46.A N LEU 42.A O no hydrogen 3.148 N/A SER 46.A OG LYS 43.A O no hydrogen 2.956 N/A SER 46.A OG GLU 79.A OE1 no hydrogen 3.457 N/A ILE 47.A N MET 44.A O no hydrogen 3.051 N/A GLN 48.A N MET 44.A O no hydrogen 3.150 N/A GLN 48.A NE2 LEU 301.A O no hydrogen 2.738 N/A LEU 49.A N ARG 45.A O no hydrogen 2.887 N/A GLN 50.A N SER 46.A O no hydrogen 2.993 N/A LEU 51.A N ILE 47.A O no hydrogen 2.851 N/A SER 52.A N GLN 48.A O no hydrogen 3.079 N/A SER 52.A OG GLN 48.A O no hydrogen 2.692 N/A SER 52.A OG ILE 294.A O no hydrogen 2.766 N/A VAL 53.A N LEU 49.A O no hydrogen 2.958 N/A MET 54.A N GLN 50.A O no hydrogen 3.159 N/A ARG 55.A N LEU 51.A O no hydrogen 2.867 N/A ARG 55.A NE GLU 313.A OE2 no hydrogen 3.257 N/A ARG 55.A NH1 GLU 298.A OE2 no hydrogen 3.405 N/A ARG 55.A NH1 GLU 309.A OE1 no hydrogen 3.038 N/A ARG 55.A NH2 GLU 309.A OE1 no hydrogen 2.798 N/A ASN 56.A N VAL 53.A O no hydrogen 3.126 N/A ARG 57.A N SER 52.A O no hydrogen 2.802 N/A ARG 57.A NH1 GLU 298.A OE2 no hydrogen 2.749 N/A CYS 65.A N GLN 63.A O no hydrogen 2.836 N/A THR 70.A N ASP 67.A OD1 no hydrogen 3.336 N/A THR 70.A OG1 ASP 67.A O no hydrogen 3.088 N/A LEU 71.A N ASP 67.A O no hydrogen 3.150 N/A THR 74.A N THR 70.A O no hydrogen 3.114 N/A THR 74.A OG1 THR 70.A O no hydrogen 2.728 N/A LEU 76.A N LEU 72.A O no hydrogen 3.012 N/A ASN 78.A N THR 74.A O no hydrogen 2.817 N/A GLU 79.A N VAL 75.A O no hydrogen 2.921 N/A THR 81.A N ARG 77.A O no hydrogen 3.193 N/A THR 81.A OG1 ARG 77.A O no hydrogen 2.798 N/A PHE 82.A N ASN 78.A O no hydrogen 2.993 N/A GLN 84.A N THR 81.A O no hydrogen 3.013 N/A GLU 85.A N THR 81.A O no hydrogen 2.979 N/A LEU 86.A N PHE 82.A O no hydrogen 2.816 N/A GLU 88.A N GLN 84.A O no hydrogen 3.324 N/A MET 89.A N GLU 85.A O no hydrogen 3.098 N/A ARG 90.A N LEU 86.A O no hydrogen 2.924 N/A ARG 90.A NH2 ASN 29.A OD1 no hydrogen 2.956 N/A ASN 91.A N GLU 87.A O no hydrogen 3.004 N/A ALA 92.A N GLU 88.A O no hydrogen 3.439 N/A SER 93.A N MET 89.A O no hydrogen 2.923 N/A SER 93.A OG ARG 90.A O no hydrogen 2.835 N/A ALA 94.A N ARG 90.A O no hydrogen 3.099 N/A LEU 95.A N ASN 91.A O no hydrogen 3.285 N/A ALA 96.A N ALA 92.A O no hydrogen 2.859 N/A ALA 97.A N SER 93.A O no hydrogen 3.151 N/A ALA 98.A N ALA 94.A O no hydrogen 3.047 N/A ALA 99.A N LEU 95.A O no hydrogen 2.847 N/A ALA 100.A N ALA 96.A O no hydrogen 2.912 N/A GLY 101.A N ALA 97.A O no hydrogen 2.860 N/A LEU 102.A N ALA 98.A O no hydrogen 2.885 N/A ALA 103.A N ALA 99.A O no hydrogen 3.163 N/A ALA 104.A N ALA 100.A O no hydrogen 2.937 N/A GLY 105.A N GLY 101.A O no hydrogen 2.816 N/A ARG 106.A N LEU 102.A O no hydrogen 3.032 N/A ARG 106.A NH1 GLY 220.A O no hydrogen 3.208 N/A LEU 107.A N ALA 103.A O no hydrogen 3.193 N/A GLU 108.A N ALA 104.A O no hydrogen 2.895 N/A GLU 109.A N GLY 105.A O no hydrogen 2.983 N/A TRP 110.A N ARG 106.A O no hydrogen 3.252 N/A ILE 111.A N LEU 107.A O no hydrogen 3.058 N/A PHE 112.A N GLU 108.A O no hydrogen 2.964 N/A VAL 113.A N GLU 109.A O no hydrogen 3.092 N/A VAL 113.A N TRP 110.A O no hydrogen 3.133 N/A PHE 114.A N TRP 110.A O no hydrogen 3.319 N/A ALA 115.A N ILE 111.A O no hydrogen 2.906 N/A GLN 116.A N PHE 112.A O no hydrogen 3.153 N/A GLN 116.A NE2 PHE 112.A O no hydrogen 3.148 N/A ALA 117.A N VAL 113.A O no hydrogen 3.247 N/A ALA 118.A N GLN 116.A O no hydrogen 2.798 N/A GLY 119.A N GLN 123.A O no hydrogen 3.037 N/A GLN 123.A N ARG 120.A O no hydrogen 3.135 N/A PHE 124.A N ASP 194.A O no hydrogen 3.003 N/A SER 127.A N LEU 6.A O no hydrogen 2.908 N/A SER 127.A OG ASN 7.A OD1 no hydrogen 2.983 N/A SER 127.A OG GLY 129.A O no hydrogen 3.382 N/A VAL 128.A N THR 131.A O no hydrogen 2.745 N/A GLY 129.A N ASN 7.A OD1 no hydrogen 3.318 N/A THR 131.A OG1 VAL 128.A O no hydrogen 3.291 N/A ALA 134.A N ILE 126.A O no hydrogen 2.952 N/A ASN 138.A ND2 GLU 135.A O no hydrogen 3.699 N/A GLU 141.A N ASN 12.A OD1 no hydrogen 3.066 N/A CYS 142.A N LEU 139.A O no hydrogen 3.339 N/A CYS 142.A SG ALA 11.A O no hydrogen 3.634 N/A PHE 143.A N LEU 139.A O no hydrogen 3.140 N/A ASP 144.A N THR 151.A O no hydrogen 2.794 N/A THR 151.A N GLY 148.A O no hydrogen 3.456 N/A THR 151.A OG1 GLY 145.A O no hydrogen 3.514 N/A THR 151.A OG1 THR 146.A O no hydrogen 2.916 N/A THR 151.A OG1 GLY 148.A O no hydrogen 3.171 N/A TYR 153.A OH GLN 140.A O no hydrogen 2.837 N/A LYS 154.A N ASP 157.A OD2 no hydrogen 2.837 N/A LYS 154.A NZ GLU 150.A O no hydrogen 3.320 N/A LYS 154.A NZ GLU 150.A OE2 no hydrogen 3.066 N/A ASP 157.A N LYS 154.A O no hydrogen 3.138 N/A VAL 160.A N ASP 157.A O no hydrogen 2.977 N/A LYS 161.A N ASP 157.A O no hydrogen 3.037 N/A LYS 161.A NZ GLU 156.A O no hydrogen 3.127 N/A GLU 162.A N SER 158.A O no hydrogen 2.744 N/A SER 163.A N ARG 159.A O no hydrogen 3.044 N/A SER 163.A OG THR 19.A O no hydrogen 3.374 N/A SER 163.A OG VAL 160.A O no hydrogen 3.274 N/A ALA 164.A N VAL 160.A O no hydrogen 3.285 N/A LYS 165.A N GLU 162.A O no hydrogen 3.260 N/A THR 166.A OG1 SER 163.A O no hydrogen 3.490 N/A LEU 168.A N THR 166.A OG1 no hydrogen 3.217 N/A GLN 169.A N GLU 172.A OE2 no hydrogen 2.959 N/A GLN 169.A NE2 GLU 172.A OE2 no hydrogen 3.145 N/A GLU 172.A N GLN 169.A O no hydrogen 3.054 N/A VAL 173.A N GLN 169.A O no hydrogen 3.314 N/A LEU 174.A N LEU 170.A O no hydrogen 2.869 N/A SER 175.A N HIS 171.A O no hydrogen 2.908 N/A SER 175.A OG HIS 171.A O no hydrogen 3.023 N/A SER 176.A N GLU 172.A O no hydrogen 3.283 N/A SER 176.A N VAL 173.A O no hydrogen 3.220 N/A SER 176.A OG VAL 173.A O no hydrogen 2.620 N/A ILE 177.A N LEU 174.A O no hydrogen 3.228 N/A SER 178.A N SER 175.A O no hydrogen 2.816 N/A SER 178.A OG SER 175.A O no hydrogen 2.913 N/A SER 178.A OG SER 181.A OG no hydrogen 3.168 N/A PHE 179.A N THR 253.A O no hydrogen 2.755 N/A SER 181.A N SER 178.A OG no hydrogen 3.246 N/A SER 181.A OG SER 175.A O no hydrogen 2.937 N/A SER 181.A OG SER 178.A OG no hydrogen 3.168 N/A LEU 182.A N SER 178.A O no hydrogen 2.914 N/A GLY 183.A N PHE 179.A O no hydrogen 2.783 N/A ASN 186.A N GLY 183.A O no hydrogen 3.057 N/A ASN 186.A ND2 LEU 182.A O no hydrogen 2.760 N/A ILE 187.A N VAL 184.A O no hydrogen 3.237 N/A ARG 188.A N VAL 184.A O no hydrogen 3.102 N/A ARG 188.A NH1 MET 234.A O no hydrogen 3.052 N/A GLY 189.A N ALA 5.A O no hydrogen 2.922 N/A GLY 190.A N GLY 129.A O no hydrogen 2.750 N/A ASN 191.A ND2 LYS 130.A O no hydrogen 3.441 N/A LYS 193.A N ASN 191.A OD1 no hydrogen 3.231 N/A ASP 194.A N ARG 3.A O no hydrogen 3.040 N/A ARG 200.A N ASN 197.A O no hydrogen 3.098 N/A ARG 200.A NE THR 203.A O no hydrogen 2.993 N/A ARG 200.A NH1 THR 203.A O no hydrogen 2.756 N/A ARG 200.A NH2 ASN 231.A O no hydrogen 2.779 N/A THR 201.A N GLN 230.A O no hydrogen 2.929 N/A THR 201.A OG1 GLN 230.A OE1 no hydrogen 2.929 N/A ASP 202.A N GLN 230.A O no hydrogen 3.094 N/A THR 203.A N ASP 202.A OD1 no hydrogen 2.807 N/A VAL 206.A N ARG 200.A O no hydrogen 2.896 N/A GLY 209.A N ASP 204.A OD1 no hydrogen 2.991 N/A SER 211.A OG THR 201.A O no hydrogen 3.134 N/A THR 218.A OG1 ASN 225.A OD1 no hydrogen 2.807 N/A TRP 219.A N MET 224.A O no hydrogen 2.870 N/A VAL 223.A N TRP 219.A O no hydrogen 3.199 N/A MET 224.A N TRP 219.A O no hydrogen 3.178 N/A ASN 225.A N ARG 251.A O no hydrogen 2.894 N/A ASN 225.A ND2 GLY 222.A O no hydrogen 3.166 N/A ASN 225.A ND2 ARG 251.A O no hydrogen 3.050 N/A PHE 226.A N LEU 217.A O no hydrogen 2.717 N/A GLY 227.A N GLN 230.A OE1 no hydrogen 2.797 N/A TYR 229.A N GLU 246.A O no hydrogen 2.946 N/A GLN 230.A N THR 201.A OG1 no hydrogen 2.823 N/A GLN 230.A NE2 THR 245.A O no hydrogen 3.174 N/A GLN 230.A NE2 GLU 246.A O no hydrogen 3.613 N/A GLN 230.A NE2 GLY 248.A O no hydrogen 2.749 N/A GLU 237.A N VAL 250.A O no hydrogen 2.920 N/A GLY 239.A N TRP 252.A O no hydrogen 2.834 N/A GLU 240.A N ASP 243.A OD2 no hydrogen 2.883 N/A ASP 243.A N GLU 240.A O no hydrogen 3.119 N/A VAL 250.A N TYR 235.A O no hydrogen 2.799 N/A ARG 251.A N ASN 225.A O no hydrogen 2.781 N/A TRP 252.A N GLU 237.A O no hydrogen 2.918 N/A TRP 252.A NE1 ILE 177.A O no hydrogen 2.776 N/A THR 253.A N VAL 223.A O no hydrogen 2.949 N/A THR 253.A OG1 GLU 240.A OE1 no hydrogen 3.092 N/A THR 253.A OG1 GLU 240.A OE2 no hydrogen 2.984 N/A GLU 254.A N GLU 240.A OE1 no hydrogen 2.886 N/A ASP 255.A N GLU 240.A OE1 no hydrogen 3.078 N/A SER 257.A N ASP 255.A OD1 no hydrogen 3.226 N/A SER 257.A OG ASP 255.A OD1 no hydrogen 2.708 N/A LYS 258.A N ASP 255.A O no hydrogen 2.981 N/A LYS 258.A NZ ASP 255.A OD2 no hydrogen 3.284 N/A VAL 259.A N PRO 256.A O no hydrogen 3.361 N/A SER 260.A OG GLY 221.A O no hydrogen 3.116 N/A PHE 262.A N VAL 259.A O no hydrogen 3.056 N/A LYS 263.A N VAL 259.A O no hydrogen 3.200 N/A LYS 263.A NZ LYS 258.A O no hydrogen 2.930 N/A ILE 266.A N PHE 262.A O no hydrogen 2.923 N/A ARG 267.A N LYS 263.A O no hydrogen 3.372 N/A ARG 267.A NH2 ASP 264.A OD2 no hydrogen 2.762 N/A LEU 268.A N ASP 264.A O no hydrogen 2.760 N/A PHE 269.A N VAL 265.A O no hydrogen 2.823 N/A ALA 270.A N ILE 266.A O no hydrogen 3.048 N/A ARG 271.A N ARG 267.A O no hydrogen 3.053 N/A PHE 272.A N LEU 268.A O no hydrogen 3.102 N/A GLN 273.A N PHE 269.A O no hydrogen 3.003 N/A GLU 274.A N ALA 270.A O no hydrogen 2.857 N/A ALA 275.A N ARG 271.A O no hydrogen 3.162 N/A LYS 276.A N PHE 272.A O no hydrogen 2.767 N/A ASN 277.A N GLN 273.A O no hydrogen 2.977 N/A ALA 278.A N GLU 274.A O no hydrogen 3.170 N/A VAL 279.A N ALA 275.A O no hydrogen 3.209 N/A VAL 280.A N LYS 276.A O no hydrogen 3.039 N/A LYS 281.A N ASN 277.A O no hydrogen 2.976 N/A LYS 282.A N ALA 278.A O no hydrogen 3.297 N/A LYS 282.A NZ GLU 85.A OE1 no hydrogen 3.139 N/A LYS 282.A NZ GLU 85.A OE2 no hydrogen 2.761 N/A ILE 283.A N VAL 279.A O no hydrogen 3.042 N/A LYS 284.A N VAL 280.A O no hydrogen 3.073 N/A LYS 284.A NZ ASP 288.A OD1 no hydrogen 2.973 N/A THR 285.A N LYS 281.A O no hydrogen 2.947 N/A THR 285.A OG1 LYS 282.A O no hydrogen 3.004 N/A THR 286.A N LYS 282.A O no hydrogen 3.148 N/A THR 286.A OG1 LYS 282.A O no hydrogen 2.774 N/A THR 286.A OG1 ILE 283.A O no hydrogen 3.103 N/A VAL 287.A N ILE 283.A O no hydrogen 2.983 N/A ASP 288.A N LYS 284.A O no hydrogen 2.990 N/A GLU 289.A N THR 285.A O no hydrogen 3.303 N/A LEU 290.A N THR 286.A O no hydrogen 3.201 N/A THR 291.A N VAL 287.A O no hydrogen 2.829 N/A THR 291.A OG1 VAL 287.A O no hydrogen 3.068 N/A THR 291.A OG1 ASP 288.A O no hydrogen 3.535 N/A LYS 292.A NZ ASP 288.A O no hydrogen 2.914 N/A CYS 293.A N LEU 290.A O no hydrogen 3.113 N/A CYS 293.A SG ASP 64.A O no hydrogen 3.922 N/A ALA 299.A N GLY 295.A O no hydrogen 2.805 N/A GLU 300.A N GLN 296.A O no hydrogen 3.273 N/A LEU 306.A N ASN 303.A O no hydrogen 2.809 N/A TYR 307.A N ASN 303.A O no hydrogen 3.178 N/A GLU 308.A N ASP 304.A O no hydrogen 3.009 N/A GLU 309.A N GLN 305.A O no hydrogen 3.052 N/A PHE 310.A N LEU 306.A O no hydrogen 2.812 N/A ILE 311.A N TYR 307.A O no hydrogen 2.844 N/A TRP 312.A N GLU 308.A O no hydrogen 3.001 N/A GLU 313.A N GLU 309.A O no hydrogen 3.207 N/A THR 314.A N PHE 310.A O no hydrogen 3.026 N/A THR 314.A OG1 PHE 310.A O no hydrogen 2.702 N/A ILE 315.A N ILE 311.A O no hydrogen 2.926 N/A ARG 317.A N GLU 313.A O no hydrogen 2.814 N/A ARG 317.A NH1 MET 54.A O no hydrogen 2.821 N/A LEU 318.A N THR 314.A O no hydrogen 3.006 N/A GLU 319.A N ILE 315.A O no hydrogen 3.209 N/A LEU 320.A N ASN 316.A O no hydrogen 3.125 N/A SER 321.A N ARG 317.A O no hydrogen 3.293 N/A SER 321.A OG LEU 318.A O no hydrogen 2.761 N/A LYS 322.A N LEU 318.A O no hydrogen 3.175 N/A ARG 323.A N LEU 320.A O no hydrogen 3.215 N/A