Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6thz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 2.A N LEU 70.A O no hydrogen 3.336 N/A PHE 4.A N PHE 72.A O no hydrogen 3.290 N/A SER 5.A N GLU 8.A OE1 no hydrogen 2.813 N/A GLU 8.A N SER 5.A O no hydrogen 3.067 N/A LYS 10.A N TYR 7.A O no hydrogen 3.209 N/A VAL 12.A N GLU 8.A O no hydrogen 3.262 N/A THR 13.A N LEU 9.A O no hydrogen 3.257 N/A THR 13.A OG1 LEU 9.A O no hydrogen 2.700 N/A THR 13.A OG1 LYS 10.A O no hydrogen 2.756 N/A ASN 14.A N ASN 11.A O no hydrogen 3.003 N/A ASN 14.A ND2 ASP 17.A OD2 no hydrogen 3.108 N/A ASN 15.A N LYS 10.A O no hydrogen 2.736 N/A PHE 16.A N THR 13.A OG1 no hydrogen 3.272 N/A ASP 17.A N THR 13.A O no hydrogen 3.160 N/A ARG 19.A NH1 ASP 17.A OD1 no hydrogen 3.383 N/A SER 22.A OG ILE 21.A O no hydrogen 2.778 N/A ASN 24.A N ASP 17.A O no hydrogen 3.262 N/A ASN 24.A ND2 VAL 12.A O no hydrogen 3.598 N/A ASN 24.A ND2 LYS 33.A O no hydrogen 2.778 N/A LYS 25.A N ASP 17.A O no hydrogen 2.838 N/A MET 26.A N VAL 31.A O no hydrogen 3.004 N/A GLY 27.A N VAL 31.A O no hydrogen 3.446 N/A VAL 30.A N LYS 45.A O no hydrogen 2.886 N/A VAL 31.A N GLY 27.A O no hydrogen 3.070 N/A TYR 32.A N VAL 43.A O no hydrogen 3.179 N/A LYS 33.A N ASN 24.A O no hydrogen 2.807 N/A VAL 36.A N THR 39.A O no hydrogen 2.769 N/A THR 39.A N VAL 36.A O no hydrogen 3.128 N/A THR 39.A OG1 VAL 36.A O no hydrogen 3.533 N/A VAL 41.A N GLY 34.A O no hydrogen 2.735 N/A ALA 42.A N TYR 77.A O no hydrogen 2.733 N/A VAL 43.A N TYR 32.A O no hydrogen 3.022 N/A LYS 44.A N LEU 75.A O no hydrogen 2.771 N/A LYS 44.A NZ GLU 54.A OE2 no hydrogen 3.515 N/A LYS 45.A N VAL 30.A O no hydrogen 2.907 N/A LYS 45.A NZ TYR 32.A OH no hydrogen 3.273 N/A LYS 48.A NZ ASP 52.A OD1 no hydrogen 3.479 N/A GLN 50.A N LEU 47.A O no hydrogen 3.220 N/A PHE 51.A N LEU 47.A O no hydrogen 3.264 N/A ASP 52.A N LYS 48.A O no hydrogen 3.392 N/A GLU 54.A N GLN 50.A O no hydrogen 3.140 N/A ILE 55.A N PHE 51.A O no hydrogen 3.333 N/A LYS 56.A N ASP 52.A O no hydrogen 3.108 N/A VAL 57.A N GLN 53.A O no hydrogen 2.795 N/A MET 58.A N GLU 54.A O no hydrogen 3.183 N/A ALA 59.A N ILE 55.A O no hydrogen 3.036 N/A LYS 60.A N LYS 56.A O no hydrogen 3.184 N/A CYS 61.A N VAL 57.A O no hydrogen 2.787 N/A ASN 65.A N HIS 63.A ND1 no hydrogen 2.997 N/A ASN 65.A ND2 ALA 140.A O no hydrogen 2.860 N/A LEU 66.A N HIS 63.A O no hydrogen 3.427 N/A VAL 67.A N ILE 142.A O no hydrogen 3.034 N/A LEU 70.A N VAL 76.A O no hydrogen 2.728 N/A LEU 75.A N LYS 44.A O no hydrogen 3.178 N/A VAL 76.A N GLY 71.A O no hydrogen 2.762 N/A TYR 77.A N ALA 42.A O no hydrogen 2.788 N/A VAL 78.A N GLU 68.A O no hydrogen 3.449 N/A TYR 79.A N THR 40.A O no hydrogen 3.042 N/A ASN 82.A N LEU 134.A O no hydrogen 2.982 N/A ASN 82.A ND2 ASP 135.A O no hydrogen 2.803 N/A GLY 83.A N MET 80.A O no hydrogen 3.258 N/A LEU 85.A N ILE 132.A O no hydrogen 2.788 N/A LEU 86.A N SER 129.A O no hydrogen 3.123 N/A ARG 88.A N SER 84.A O no hydrogen 3.121 N/A ARG 88.A NE THR 95.A OG1 no hydrogen 2.783 N/A ARG 88.A NH1 LEU 92.A O no hydrogen 2.918 N/A ARG 88.A NH1 THR 95.A OG1 no hydrogen 3.299 N/A ARG 88.A NH2 ASN 82.A O no hydrogen 2.784 N/A LEU 89.A N LEU 85.A O no hydrogen 2.799 N/A SER 90.A N LEU 86.A O no hydrogen 3.053 N/A SER 90.A OG LEU 86.A O no hydrogen 3.147 N/A SER 90.A OG ASP 87.A O no hydrogen 3.279 N/A CYS 91.A N ARG 88.A O no hydrogen 3.237 N/A CYS 91.A SG ARG 88.A O no hydrogen 4.042 N/A LEU 92.A N ASP 87.A O no hydrogen 2.882 N/A GLY 94.A N CYS 91.A O no hydrogen 3.128 N/A THR 95.A OG1 LEU 92.A O no hydrogen 3.354 N/A TRP 100.A N ASP 227.A OD1 no hydrogen 2.724 N/A TRP 100.A NE1 SER 232.A OG no hydrogen 2.767 N/A HIS 101.A N ASP 227.A OD2 no hydrogen 3.235 N/A MET 102.A N SER 99.A OG no hydrogen 3.321 N/A ARG 103.A N SER 99.A O no hydrogen 2.935 N/A ARG 103.A NE LEU 98.A O no hydrogen 2.893 N/A ARG 103.A NH1 ILE 187.A O no hydrogen 2.772 N/A ARG 103.A NH1 ASP 222.A OD2 no hydrogen 2.886 N/A ARG 103.A NH2 LEU 98.A O no hydrogen 3.013 N/A ARG 103.A NH2 ASP 222.A OD2 no hydrogen 2.816 N/A CYS 104.A N TRP 100.A O no hydrogen 2.915 N/A CYS 104.A SG TRP 100.A O no hydrogen 3.311 N/A LYS 105.A N HIS 101.A O no hydrogen 3.368 N/A LYS 105.A NZ ALA 137.A O no hydrogen 3.264 N/A ILE 106.A N MET 102.A O no hydrogen 2.992 N/A ALA 107.A N ARG 103.A O no hydrogen 2.876 N/A GLN 108.A N CYS 104.A O no hydrogen 2.869 N/A GLN 108.A NE2 LEU 261.A O no hydrogen 2.932 N/A GLN 108.A NE2 THR 265.A OG1 no hydrogen 2.797 N/A GLY 109.A N LYS 105.A O no hydrogen 2.874 N/A ALA 110.A N ILE 106.A O no hydrogen 2.913 N/A ALA 111.A N ALA 107.A O no hydrogen 2.996 N/A ASN 112.A N GLN 108.A O no hydrogen 3.108 N/A ASN 112.A ND2 ASN 65.A OD1 no hydrogen 3.658 N/A GLY 113.A N GLY 109.A O no hydrogen 3.074 N/A ILE 114.A N ALA 110.A O no hydrogen 3.092 N/A ASN 115.A N ALA 111.A O no hydrogen 2.832 N/A ASN 115.A ND2 GLU 119.A OE1 no hydrogen 3.109 N/A PHE 116.A N ASN 112.A O no hydrogen 3.054 N/A LEU 117.A N GLY 113.A O no hydrogen 3.136 N/A HIS 118.A N ILE 114.A O no hydrogen 2.854 N/A HIS 118.A NE2 ASP 176.A OD2 no hydrogen 3.239 N/A GLU 119.A N ASN 115.A O no hydrogen 2.930 N/A ASN 120.A N PHE 116.A O no hydrogen 3.122 N/A ASN 120.A N LEU 117.A O no hydrogen 3.281 N/A ASN 120.A ND2 PHE 116.A O no hydrogen 2.817 N/A HIS 122.A N LEU 117.A O no hydrogen 2.891 N/A HIS 122.A ND1 ASN 120.A O no hydrogen 3.232 N/A ILE 123.A N ARG 149.A O no hydrogen 2.794 N/A HIS 124.A N ASP 176.A OD2 no hydrogen 2.792 N/A HIS 124.A NE2 SER 143.A O no hydrogen 2.773 N/A ARG 125.A N ASP 176.A OD1 no hydrogen 3.012 N/A ARG 125.A NE LEU 147.A O no hydrogen 3.049 N/A ASP 126.A N HIS 124.A ND1 no hydrogen 3.171 N/A LYS 128.A NZ THR 158.A OG1 no hydrogen 3.114 N/A SER 129.A OG TYR 161.A OH no hydrogen 3.174 N/A SER 129.A OG GLU 186.A OE1 no hydrogen 3.224 N/A SER 129.A OG GLU 186.A OE2 no hydrogen 2.898 N/A ASN 131.A N LYS 128.A O no hydrogen 2.869 N/A ASN 131.A ND2 ASP 126.A O no hydrogen 2.778 N/A ASN 131.A ND2 ASP 126.A OD2 no hydrogen 3.275 N/A LEU 133.A N LYS 141.A O no hydrogen 2.858 N/A LEU 134.A N GLY 83.A O no hydrogen 2.806 N/A ASP 135.A N THR 139.A O no hydrogen 3.293 N/A ALA 137.A N ASP 135.A OD1 no hydrogen 2.852 N/A PHE 138.A N ASP 135.A O no hydrogen 3.239 N/A THR 139.A N ASP 135.A OD1 no hydrogen 2.817 N/A THR 139.A OG1 ASP 135.A OD1 no hydrogen 3.328 N/A THR 139.A OG1 ASP 135.A OD2 no hydrogen 3.432 N/A LYS 141.A N LEU 133.A O no hydrogen 2.793 N/A LYS 141.A NZ GLU 64.A O no hydrogen 2.761 N/A ILE 142.A N ASN 65.A O no hydrogen 2.896 N/A SER 143.A N ASN 131.A O no hydrogen 2.832 N/A SER 143.A OG ASN 131.A O no hydrogen 3.448 N/A PHE 145.A N GLU 54.A OE1 no hydrogen 3.159 N/A ALA 148.A N PHE 145.A O no hydrogen 3.278 N/A ARG 149.A N ILE 123.A O no hydrogen 2.859 N/A THR 158.A OG1 ASP 126.A OD1 no hydrogen 2.969 N/A TYR 161.A N THR 158.A O no hydrogen 2.904 N/A TYR 161.A OH SER 129.A OG no hydrogen 3.174 N/A TYR 161.A OH GLU 186.A OE1 no hydrogen 2.722 N/A TYR 161.A OH GLU 186.A OE2 no hydrogen 3.104 N/A MET 162.A N THR 159.A O no hydrogen 3.448 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.890 N/A ALA 166.A N ALA 163.A O no hydrogen 3.092 N/A LEU 167.A N ALA 163.A O no hydrogen 3.150 N/A LEU 167.A N PRO 164.A O no hydrogen 3.035 N/A GLY 169.A N ALA 166.A O no hydrogen 3.377 N/A GLU 170.A N GLU 165.A O no hydrogen 2.987 N/A ILE 171.A N VAL 152.A O no hydrogen 2.790 N/A LYS 174.A N THR 172.A OG1 no hydrogen 3.202 N/A SER 175.A N THR 172.A O no hydrogen 2.991 N/A SER 175.A OG GLU 165.A OE2 no hydrogen 2.810 N/A SER 175.A OG THR 172.A O no hydrogen 3.329 N/A ASP 176.A N PRO 173.A O no hydrogen 3.180 N/A TYR 178.A N LYS 174.A O no hydrogen 3.428 N/A SER 179.A N SER 175.A O no hydrogen 3.116 N/A SER 179.A OG TYR 161.A O no hydrogen 2.763 N/A SER 179.A OG SER 175.A O no hydrogen 3.273 N/A PHE 180.A N ASP 176.A O no hydrogen 2.969 N/A GLY 181.A N ILE 177.A O no hydrogen 3.159 N/A VAL 182.A N TYR 178.A O no hydrogen 3.284 N/A VAL 182.A N SER 179.A O no hydrogen 3.179 N/A VAL 183.A N SER 179.A O no hydrogen 3.194 N/A LEU 184.A N PHE 180.A O no hydrogen 2.850 N/A LEU 185.A N GLY 181.A O no hydrogen 3.166 N/A GLU 186.A N VAL 182.A O no hydrogen 3.132 N/A ILE 187.A N VAL 183.A O no hydrogen 2.989 N/A ILE 188.A N LEU 184.A O no hydrogen 3.079 N/A THR 189.A N LEU 185.A O no hydrogen 2.987 N/A THR 189.A OG1 LEU 185.A O no hydrogen 2.811 N/A GLY 190.A N GLU 186.A O no hydrogen 2.737 N/A LEU 191.A N THR 189.A OG1 no hydrogen 3.143 N/A ASP 195.A N GLN 201.A O no hydrogen 3.072 N/A GLU 196.A N GLU 196.A OE1 no hydrogen 3.251 N/A ARG 198.A NE PRO 200.A O no hydrogen 2.923 N/A ARG 198.A NH1 PRO 192.A O no hydrogen 2.778 N/A ARG 198.A NH2 PRO 192.A O no hydrogen 2.959 N/A GLN 201.A NE2 ARG 198.A O no hydrogen 3.023 N/A LEU 203.A N ALA 193.A O no hydrogen 2.977 N/A ASP 205.A N LEU 202.A O no hydrogen 3.106 N/A ILE 206.A N LEU 203.A O no hydrogen 3.006 N/A GLU 208.A N ASP 205.A O no hydrogen 3.095 N/A GLU 209.A N ASP 205.A O no hydrogen 3.382 N/A ILE 210.A N ILE 206.A O no hydrogen 2.994 N/A GLU 211.A N LYS 207.A O no hydrogen 3.115 N/A ASP 212.A N GLU 208.A O no hydrogen 2.889 N/A GLU 213.A N ILE 210.A O no hydrogen 3.117 N/A GLU 214.A N GLU 209.A O no hydrogen 2.903 N/A LYS 215.A N GLU 209.A O no hydrogen 3.368 N/A LYS 215.A NZ GLU 209.A OE2 no hydrogen 3.357 N/A LYS 215.A NZ GLU 214.A OE1 no hydrogen 3.489 N/A THR 216.A OG1 ASP 219.A OD1 no hydrogen 2.725 N/A TYR 220.A N ILE 217.A O no hydrogen 2.887 N/A TYR 220.A OH GLU 209.A OE2 no hydrogen 3.066 N/A ASP 222.A N ILE 188.A O no hydrogen 2.886 N/A LYS 224.A N ASP 222.A OD1 no hydrogen 3.084 N/A LYS 224.A NZ ASP 222.A OD1 no hydrogen 2.960 N/A SER 230.A OG GLU 218.A OE1 no hydrogen 3.113 N/A SER 232.A N ASP 229.A OD2 no hydrogen 3.200 N/A SER 232.A OG ASP 229.A O no hydrogen 3.369 N/A SER 232.A OG ASP 229.A OD1 no hydrogen 2.696 N/A SER 232.A OG ASP 229.A OD2 no hydrogen 3.389 N/A VAL 233.A N ASP 229.A O no hydrogen 3.056 N/A GLU 234.A N SER 230.A O no hydrogen 2.839 N/A ALA 235.A N THR 231.A O no hydrogen 3.113 N/A MET 236.A N SER 232.A O no hydrogen 3.003 N/A TYR 237.A N VAL 233.A O no hydrogen 2.999 N/A SER 238.A N GLU 234.A O no hydrogen 2.945 N/A SER 238.A OG GLN 242.A OE1 no hydrogen 3.532 N/A VAL 239.A N ALA 235.A O no hydrogen 3.408 N/A ALA 240.A N MET 236.A O no hydrogen 2.925 N/A SER 241.A N TYR 237.A O no hydrogen 2.714 N/A GLN 242.A N SER 238.A O no hydrogen 3.155 N/A CYS 243.A N VAL 239.A O no hydrogen 3.019 N/A CYS 243.A SG VAL 239.A O no hydrogen 3.306 N/A LEU 244.A N ALA 240.A O no hydrogen 3.078 N/A LYS 247.A N HIS 245.A ND1 no hydrogen 3.170 N/A LYS 248.A NZ GLU 170.A OE1 no hydrogen 2.800 N/A LYS 250.A N LYS 247.A O no hydrogen 2.776 N/A ARG 251.A NE HIS 245.A O no hydrogen 2.772 N/A ARG 251.A NH1 GLU 165.A OE2 no hydrogen 2.871 N/A ARG 251.A NH1 LYS 174.A O no hydrogen 2.815 N/A ARG 251.A NH2 GLU 165.A OE1 no hydrogen 2.888 N/A ARG 251.A NH2 HIS 245.A O no hydrogen 3.316 N/A LYS 255.A NZ GLU 119.A OE2 no hydrogen 2.858 N/A LYS 256.A N ASP 253.A O no hydrogen 3.091 N/A VAL 257.A N ASP 253.A O no hydrogen 3.037 N/A GLN 258.A N ILE 254.A O no hydrogen 2.940 N/A GLN 258.A NE2 ASN 112.A OD1 no hydrogen 2.793 N/A GLN 259.A N LYS 255.A O no hydrogen 3.225 N/A LEU 260.A N LYS 256.A O no hydrogen 2.845 N/A LEU 261.A N VAL 257.A O no hydrogen 3.091 N/A GLN 262.A N GLN 258.A O no hydrogen 3.287 N/A GLU 263.A N GLN 259.A O no hydrogen 3.106 N/A MET 264.A N LEU 261.A O no hydrogen 3.277 N/A THR 265.A N GLN 262.A O no hydrogen 2.902 N/A THR 265.A OG1 GLN 262.A O no hydrogen 3.219 N/A