Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6v12_1.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 7.A OG SER 8.A O no hydrogen 3.297 N/A SER 9.A N ASN 103.A OD1 no hydrogen 2.808 N/A HIS 13.A N THR 28.A OG1 no hydrogen 3.168 N/A CYS 14.A SG HIS 13.A O no hydrogen 3.247 N/A CYS 14.A SG THR 28.A O no hydrogen 3.906 N/A ASP 15.A N THR 26.A O no hydrogen 3.449 N/A SER 16.A N ASP 15.A OD1 no hydrogen 2.399 N/A SER 16.A OG ASP 81.A OD1 no hydrogen 3.506 N/A SER 16.A OG ASP 81.A OD2 no hydrogen 3.004 N/A THR 17.A N ILE 24.A O no hydrogen 3.132 N/A LEU 19.A N ARG 22.A O no hydrogen 2.983 N/A ARG 22.A N LEU 19.A O no hydrogen 2.831 N/A ARG 22.A NE GLU 469.A OE2 no hydrogen 3.163 N/A VAL 23.A N TRP 470.A O no hydrogen 3.083 N/A ILE 24.A N THR 17.A O no hydrogen 3.004 N/A THR 25.A N ILE 468.A O no hydrogen 2.952 N/A THR 25.A OG1 ILE 468.A O no hydrogen 3.513 N/A THR 26.A N ASP 15.A O no hydrogen 3.002 N/A SER 27.A N VAL 466.A O no hydrogen 2.935 N/A SER 27.A OG CYS 75.A O no hydrogen 3.283 N/A THR 28.A OG1 HIS 13.A O no hydrogen 2.363 N/A THR 28.A OG1 SER 465.A OG no hydrogen 3.065 N/A ARG 29.A N VAL 464.A O no hydrogen 3.025 N/A ARG 29.A NE PRO 149.A O no hydrogen 3.191 N/A ARG 29.A NH1 THR 28.A O no hydrogen 2.571 N/A ARG 29.A NH2 PRO 149.A O no hydrogen 3.438 N/A THR 30.A OG1 GLN 463.A OE1 no hydrogen 2.905 N/A TRP 31.A N GLY 462.A O no hydrogen 3.124 N/A ALA 32.A N PHE 156.A O no hydrogen 3.123 N/A LEU 33.A N SER 460.A O no hydrogen 2.758 N/A THR 35.A OG1 GLN 458.A O no hydrogen 3.141 N/A TYR 36.A OH ILE 158.A O no hydrogen 2.206 N/A ASN 37.A ND2 LEU 40.A O no hydrogen 3.353 N/A ASN 37.A ND2 SER 62.A OG no hydrogen 3.217 N/A HIS 39.A N TYR 36.A O no hydrogen 3.053 N/A TYR 41.A OH GLU 182.A OE1 no hydrogen 2.316 N/A TYR 41.A OH GLU 182.A OE2 no hydrogen 3.144 N/A LYS 42.A N SER 62.A O no hydrogen 3.244 N/A ILE 44.A N GLY 60.A O no hydrogen 2.743 N/A SER 45.A OG TYR 58.A O no hydrogen 3.334 N/A SER 45.A OG SER 170.A O no hydrogen 2.939 N/A ASN 46.A N TYR 58.A O no hydrogen 3.018 N/A THR 48.A OG1 ALA 52.A O no hydrogen 3.339 N/A ASN 56.A N THR 53.A O no hydrogen 3.071 N/A THR 57.A OG1 ASN 54.A O no hydrogen 3.257 N/A TYR 58.A N ASN 46.A O no hydrogen 3.072 N/A GLY 60.A N ILE 44.A O no hydrogen 2.958 N/A TYR 61.A N TYR 163.A O no hydrogen 3.040 N/A SER 62.A N LYS 42.A O no hydrogen 2.924 N/A THR 63.A N TYR 161.A O no hydrogen 2.979 N/A THR 63.A OG1 TYR 161.A O no hydrogen 2.312 N/A GLY 66.A N ILE 434.A O no hydrogen 2.931 N/A TYR 67.A N PRO 159.A O no hydrogen 3.369 N/A PHE 68.A N ILE 432.A O no hydrogen 3.332 N/A ASN 71.A N ASP 69.A OD1 no hydrogen 2.902 N/A ASN 71.A ND2 TRP 404.A O no hydrogen 3.169 N/A ARG 72.A NE GLN 400.A O no hydrogen 2.874 N/A ARG 72.A NH2 GLN 400.A O no hydrogen 3.093 N/A PHE 73.A N GLY 401.A O no hydrogen 3.122 N/A CYS 75.A N ARG 72.A O no hydrogen 3.384 N/A CYS 75.A SG LEU 148.A O no hydrogen 3.371 N/A HIS 76.A N PHE 73.A O no hydrogen 2.690 N/A HIS 76.A NE2 PHE 70.A O no hydrogen 3.091 N/A ARG 80.A NH1 ARG 80.A O no hydrogen 3.254 N/A ASP 81.A N SER 78.A OG no hydrogen 3.243 N/A TRP 82.A N SER 78.A O no hydrogen 2.838 N/A GLN 83.A N PRO 79.A O no hydrogen 3.049 N/A GLN 83.A N ARG 80.A O no hydrogen 2.916 N/A GLN 83.A NE2 TYR 486.A O no hydrogen 2.873 N/A ARG 84.A N ARG 80.A O no hydrogen 3.035 N/A LEU 85.A N ASP 81.A O no hydrogen 3.018 N/A ILE 86.A N TRP 82.A O no hydrogen 3.079 N/A ASN 87.A N GLN 83.A O no hydrogen 3.196 N/A ASN 87.A ND2 TYR 486.A O no hydrogen 3.625 N/A ASN 88.A ND2 ARG 84.A O no hydrogen 3.026 N/A ASN 89.A ND2 LEU 85.A O no hydrogen 3.129 N/A TRP 90.A N GLN 473.A O no hydrogen 3.086 N/A ARG 93.A N GLU 471.A O no hydrogen 3.018 N/A ARG 93.A NE GLU 471.A OE1 no hydrogen 2.975 N/A ARG 93.A NH1 VAL 204.A O no hydrogen 2.858 N/A ARG 93.A NH2 GLU 471.A OE1 no hydrogen 3.199 N/A LYS 95.A N GLU 469.A O no hydrogen 2.736 N/A LYS 95.A NZ GLU 471.A OE1 no hydrogen 3.001 N/A LEU 97.A N TYR 199.A O no hydrogen 2.926 N/A SER 98.A N GLU 467.A O no hydrogen 2.725 N/A PHE 99.A N PHE 197.A O no hydrogen 3.061 N/A LYS 100.A N SER 465.A O no hydrogen 2.758 N/A LEU 101.A N PHE 195.A O no hydrogen 2.787 N/A PHE 102.A N GLN 463.A O no hydrogen 3.274 N/A ASN 103.A ND2 GLY 10.A O no hydrogen 3.165 N/A GLN 105.A N THR 461.A O no hydrogen 2.844 N/A LYS 107.A N TYR 459.A O no hydrogen 2.757 N/A LYS 107.A NZ ASN 120.A OD1 no hydrogen 2.183 N/A GLU 108.A N ALA 119.A O no hydrogen 3.029 N/A VAL 109.A N THR 457.A O no hydrogen 3.151 N/A THR 110.A N THR 117.A O no hydrogen 3.191 N/A ASN 112.A N THR 115.A O no hydrogen 3.261 N/A THR 115.A N ASN 112.A O no hydrogen 2.971 N/A ALA 119.A N GLU 108.A O no hydrogen 3.158 N/A ASN 121.A N VAL 106.A O no hydrogen 3.004 N/A THR 123.A N ASN 121.A OD1 no hydrogen 3.365 N/A THR 123.A OG1 ASN 121.A OD1 no hydrogen 3.252 N/A THR 125.A OG1 THR 437.A OG1 no hydrogen 2.871 N/A ILE 126.A N LEU 189.A O no hydrogen 2.941 N/A GLN 127.A N LYS 435.A O no hydrogen 2.875 N/A VAL 128.A N GLN 187.A O no hydrogen 2.908 N/A PHE 129.A N LEU 433.A O no hydrogen 3.183 N/A ASP 131.A N GLN 431.A O no hydrogen 3.312 N/A GLU 133.A N ASP 131.A OD1 no hydrogen 3.080 N/A TYR 134.A OH PRO 428.A O no hydrogen 2.282 N/A GLN 135.A N ASP 131.A OD1 no hydrogen 3.244 N/A VAL 139.A N GLN 431.A OE1 no hydrogen 3.464 N/A LEU 148.A N ASP 69.A O no hydrogen 3.337 N/A ASP 154.A N PHE 151.A O no hydrogen 3.042 N/A PHE 156.A N THR 30.A O no hydrogen 3.158 N/A ILE 158.A N ALA 32.A O no hydrogen 3.372 N/A GLN 160.A NE2 THR 63.A O no hydrogen 2.905 N/A TYR 161.A N TRP 65.A O no hydrogen 3.218 N/A TYR 161.A OH PRO 137.A O no hydrogen 2.875 N/A TYR 163.A N TYR 61.A O no hydrogen 3.064 N/A THR 165.A N PHE 59.A O no hydrogen 2.931 N/A ASN 167.A ND2 GLY 169.A O no hydrogen 3.231 N/A ASN 168.A N GLN 171.A O no hydrogen 3.069 N/A GLN 171.A N ASN 168.A O no hydrogen 3.003 N/A VAL 173.A N SER 176.A OG no hydrogen 3.259 N/A SER 176.A N VAL 173.A O no hydrogen 3.445 N/A SER 176.A OG LEU 166.A O no hydrogen 2.958 N/A SER 176.A OG VAL 173.A O no hydrogen 3.204 N/A SER 177.A OG ARG 175.A O no hydrogen 3.405 N/A TYR 179.A N TYR 163.A OH no hydrogen 2.794 N/A CYS 180.A SG GLU 182.A OE1 no hydrogen 3.209 N/A LEU 181.A N TYR 41.A OH no hydrogen 2.889 N/A GLU 182.A N GLU 182.A OE1 no hydrogen 2.593 N/A TYR 183.A N CYS 180.A O no hydrogen 3.033 N/A PHE 184.A N LEU 181.A O no hydrogen 3.464 N/A GLN 187.A N VAL 128.A O no hydrogen 2.808 N/A LEU 189.A N ILE 126.A O no hydrogen 2.908 N/A ARG 190.A N ASN 193.A OD1 no hydrogen 3.093 N/A THR 191.A OG1 ILE 104.A O no hydrogen 2.631 N/A ASN 193.A N ARG 190.A O no hydrogen 3.017 N/A PHE 195.A N LEU 101.A O no hydrogen 2.865 N/A PHE 197.A N PHE 99.A O no hydrogen 3.173 N/A TYR 199.A N LEU 97.A O no hydrogen 3.024 N/A TYR 199.A OH HIS 427.A O no hydrogen 2.087 N/A PHE 201.A N LYS 95.A O no hydrogen 2.782 N/A HIS 207.A N PHE 92.A O no hydrogen 3.128 N/A SER 208.A OG GLN 393.A OE1 no hydrogen 3.417 N/A SER 209.A N TRP 90.A O no hydrogen 2.676 N/A SER 209.A OG ASN 89.A O no hydrogen 3.274 N/A SER 209.A OG TRP 90.A O no hydrogen 2.223 N/A SER 209.A OG SER 209.A O no hydrogen 2.531 N/A ALA 211.A N LEU 517.A O no hydrogen 2.780 N/A SER 213.A N ARG 519.A O no hydrogen 2.465 N/A SER 213.A OG ARG 519.A O no hydrogen 2.930 N/A SER 215.A OG ASP 217.A OD1 no hydrogen 2.850 N/A ARG 218.A N SER 215.A O no hydrogen 3.142 N/A LEU 223.A N ASN 221.A OD1 no hydrogen 2.801 N/A GLN 226.A N GLY 251.A O no hydrogen 3.051 N/A GLN 226.A NE2 ALA 260.A O no hydrogen 3.210 N/A TYR 230.A N SER 249.A O no hydrogen 2.911 N/A SER 232.A N GLY 247.A O no hydrogen 3.097 N/A SER 232.A OG SER 249.A OG no hydrogen 2.888 N/A ARG 233.A N GLY 247.A O no hydrogen 3.383 N/A ARG 233.A NH1 GLN 235.A O no hydrogen 3.432 N/A GLN 235.A NE2 ASN 242.A O no hydrogen 2.941 N/A THR 236.A N THR 243.A O no hydrogen 2.968 N/A THR 236.A OG1 ASN 242.A OD1 no hydrogen 3.454 N/A THR 236.A OG1 THR 243.A O no hydrogen 3.298 N/A GLY 239.A N ASN 242.A OD1 no hydrogen 3.152 N/A THR 243.A N THR 236.A OG1 no hydrogen 2.951 N/A GLN 244.A N GLN 244.A OE1 no hydrogen 2.627 N/A THR 245.A N THR 234.A O no hydrogen 2.894 N/A GLY 247.A N ARG 233.A O no hydrogen 3.161 N/A SER 249.A N TYR 230.A O no hydrogen 3.119 N/A SER 249.A OG SER 232.A OG no hydrogen 2.888 N/A GLY 252.A N THR 255.A O no hydrogen 3.476 N/A ALA 260.A N GLN 226.A OE1 no hydrogen 3.277 N/A LYS 261.A NZ MET 256.A O no hydrogen 3.320 N/A LYS 261.A NZ GLN 259.A O no hydrogen 3.188 N/A LEU 264.A N GLY 389.A O no hydrogen 2.913 N/A CYS 268.A N GLN 384.A O no hydrogen 3.232 N/A CYS 268.A SG GLU 360.A O no hydrogen 3.713 N/A CYS 268.A SG ASN 382.A O no hydrogen 4.039 N/A TYR 269.A OH LYS 293.A O no hydrogen 3.100 N/A GLN 271.A N ALA 358.A O no hydrogen 3.111 N/A ARG 273.A N GLN 272.A OE1 no hydrogen 2.998 N/A VAL 274.A N PHE 320.A O no hydrogen 2.984 N/A SER 275.A N ASN 281.A OD1 no hydrogen 2.755 N/A SER 275.A OG THR 277.A O no hydrogen 3.212 N/A SER 275.A OG GLN 280.A OE1 no hydrogen 2.719 N/A THR 276.A N ARG 318.A O no hydrogen 2.627 N/A THR 276.A OG1 ARG 318.A O no hydrogen 3.019 N/A THR 277.A N SER 275.A OG no hydrogen 3.186 N/A ASN 281.A N THR 278.A O no hydrogen 3.017 N/A ASN 281.A ND2 SER 275.A O no hydrogen 2.858 N/A THR 289.A OG1 PHE 286.A O no hydrogen 3.366 N/A ALA 290.A N PHE 286.A O no hydrogen 2.662 N/A THR 292.A OG1 ARG 270.A O no hydrogen 3.161 N/A THR 292.A OG1 GLN 271.A OE1 no hydrogen 3.117 N/A LYS 293.A NZ TRP 288.A O no hydrogen 3.332 N/A LYS 293.A NZ THR 289.A O no hydrogen 3.427 N/A LYS 293.A NZ GLY 291.A O no hydrogen 3.464 N/A TYR 294.A N SER 301.A O no hydrogen 2.819 N/A LEU 296.A N ARG 299.A O no hydrogen 3.072 N/A ARG 299.A N LEU 296.A O no hydrogen 3.014 N/A ARG 299.A NH2 ASN 167.A OD1 no hydrogen 3.256 N/A ASN 300.A N ASP 55.A OD1 no hydrogen 3.250 N/A SER 301.A N TYR 294.A O no hydrogen 2.933 N/A SER 301.A OG TYR 294.A OH no hydrogen 3.236 N/A SER 301.A OG LEU 302.A O no hydrogen 3.371 N/A ALA 303.A N THR 292.A O no hydrogen 3.110 N/A ALA 310.A N PRO 356.A O no hydrogen 3.232 N/A HIS 312.A ND1 LYS 313.A O no hydrogen 2.735 N/A GLU 316.A N LYS 313.A O no hydrogen 3.224 N/A ARG 318.A NE GLN 280.A OE1 no hydrogen 3.395 N/A PHE 319.A N GLU 316.A O no hydrogen 2.603 N/A PHE 320.A N VAL 274.A O no hydrogen 2.880 N/A SER 322.A N GLN 272.A O no hydrogen 2.727 N/A ASN 323.A ND2 THR 292.A O no hydrogen 3.571 N/A PHE 328.A N MET 344.A O no hydrogen 2.970 N/A LYS 330.A N ASP 342.A O no hydrogen 2.888 N/A LYS 330.A NZ SER 341.A O no hydrogen 2.596 N/A SER 341.A N ASP 339.A OD2 no hydrogen 2.930 N/A SER 341.A OG ASP 339.A OD2 no hydrogen 2.624 N/A ASP 342.A N ASP 339.A O no hydrogen 3.006 N/A VAL 343.A N TYR 340.A O no hydrogen 3.382 N/A MET 344.A N PHE 328.A O no hydrogen 2.522 N/A THR 346.A N LEU 326.A O no hydrogen 3.261 N/A THR 346.A OG1 LEU 326.A O no hydrogen 2.662 N/A GLU 348.A N THR 311.A OG1 no hydrogen 2.843 N/A GLU 349.A N SER 347.A OG no hydrogen 3.390 N/A GLU 350.A N GLU 350.A OE1 no hydrogen 2.454 N/A ILE 351.A N GLU 348.A O no hydrogen 3.013 N/A LYS 352.A N GLU 349.A O no hydrogen 3.221 N/A LYS 352.A NZ ASP 314.A OD1 no hydrogen 2.251 N/A LYS 352.A NZ GLU 349.A OE2 no hydrogen 3.184 N/A THR 353.A OG1 THR 354.A OG1 no hydrogen 3.401 N/A THR 354.A OG1 THR 353.A OG1 no hydrogen 3.401 N/A ASN 355.A N ILE 351.A O no hydrogen 3.014 N/A ALA 358.A N ALA 310.A O no hydrogen 2.879 N/A GLU 360.A N VAL 357.A O no hydrogen 3.379 N/A GLU 361.A N GLU 361.A OE1 no hydrogen 2.464 N/A TYR 362.A N VAL 381.A O no hydrogen 2.911 N/A TYR 362.A OH PRO 265.A O no hydrogen 3.310 N/A VAL 365.A N GLY 379.A O no hydrogen 2.850 N/A ASP 367.A N GLN 377.A O no hydrogen 3.028 N/A ASN 368.A ND2 ALA 375.A O no hydrogen 2.698 N/A GLN 371.A N THR 374.A O no hydrogen 3.267 N/A GLN 377.A N ASN 368.A OD1 no hydrogen 2.458 N/A GLY 379.A N VAL 365.A O no hydrogen 2.694 N/A VAL 381.A N GLY 363.A O no hydrogen 3.239 N/A GLN 384.A N CYS 268.A O no hydrogen 2.615 N/A MET 390.A N LEU 387.A O no hydrogen 3.255 N/A VAL 391.A N LEU 264.A O no hydrogen 3.167 N/A GLN 393.A N ASN 355.A OD1 no hydrogen 3.270 N/A ARG 395.A NE LEU 419.A O no hydrogen 3.239 N/A ARG 395.A NH2 GLY 306.A O no hydrogen 3.219 N/A ASP 396.A N GLU 348.A OE1 no hydrogen 3.439 N/A TYR 398.A OH GLU 348.A OE2 no hydrogen 2.840 N/A LEU 399.A N ILE 512.A O no hydrogen 3.422 N/A GLN 400.A NE2 GLU 508.A OE1 no hydrogen 2.992 N/A GLN 400.A NE2 ARG 510.A O no hydrogen 3.601 N/A GLY 401.A N TYR 398.A O no hydrogen 2.840 N/A ILE 403.A N ASN 71.A O no hydrogen 2.615 N/A TRP 404.A N ASN 71.A OD1 no hydrogen 3.162 N/A TRP 404.A NE1 TYR 138.A OH no hydrogen 2.917 N/A ALA 405.A N PHE 423.A O no hydrogen 3.188 N/A LYS 406.A NZ LYS 426.A O no hydrogen 3.366 N/A ILE 407.A N LEU 425.A O no hydrogen 2.940 N/A THR 410.A OG1 GLY 412.A O no hydrogen 3.356 N/A HIS 415.A NE2 ASN 394.A OD1 no hydrogen 3.020 N/A SER 417.A N HIS 415.A O no hydrogen 2.572 N/A GLY 421.A N PRO 418.A O no hydrogen 3.008 N/A PHE 423.A N ILE 403.A O no hydrogen 2.937 N/A LEU 425.A N ALA 405.A O no hydrogen 3.105 N/A LYS 426.A N GLU 202.A OE2 no hydrogen 2.589 N/A HIS 427.A N GLU 202.A OE2 no hydrogen 3.274 N/A GLN 431.A NE2 PRO 137.A O no hydrogen 3.061 N/A LEU 433.A N PHE 129.A O no hydrogen 2.931 N/A ILE 434.A N GLY 66.A O no hydrogen 2.683 N/A LYS 435.A N GLN 127.A O no hydrogen 3.038 N/A LYS 435.A NZ GLN 127.A OE1 no hydrogen 3.220 N/A LYS 435.A NZ ASN 436.A O no hydrogen 3.204 N/A ASN 436.A ND2 SER 460.A OG no hydrogen 2.894 N/A THR 437.A N THR 125.A O no hydrogen 3.364 N/A THR 437.A OG1 THR 125.A OG1 no hydrogen 2.871 N/A ALA 441.A N SER 454.A O no hydrogen 3.166 N/A ILE 456.A N VAL 439.A O no hydrogen 3.172 N/A TYR 459.A N LYS 107.A O no hydrogen 2.892 N/A SER 460.A N LEU 33.A O no hydrogen 3.385 N/A THR 461.A N GLN 105.A O no hydrogen 2.865 N/A THR 461.A OG1 GLN 105.A OE1 no hydrogen 3.295 N/A GLY 462.A N TRP 31.A O no hydrogen 3.261 N/A GLN 463.A N PHE 102.A O no hydrogen 2.986 N/A GLN 463.A NE2 THR 30.A OG1 no hydrogen 3.090 N/A VAL 464.A N ARG 29.A O no hydrogen 3.093 N/A SER 465.A N LYS 100.A O no hydrogen 2.763 N/A SER 465.A OG THR 28.A OG1 no hydrogen 3.065 N/A VAL 466.A N SER 27.A O no hydrogen 3.233 N/A GLU 467.A N SER 98.A O no hydrogen 2.899 N/A ILE 468.A N THR 25.A O no hydrogen 2.862 N/A GLU 469.A N ARG 96.A O no hydrogen 2.852 N/A TRP 470.A N VAL 23.A O no hydrogen 2.760 N/A GLU 471.A N ARG 93.A O no hydrogen 2.776 N/A LEU 472.A N ASP 21.A O no hydrogen 2.593 N/A GLN 473.A N GLY 91.A O no hydrogen 2.762 N/A ARG 479.A N SER 477.A OG no hydrogen 3.381 N/A ARG 479.A NE ASN 481.A OD1 no hydrogen 2.514 N/A ARG 479.A NH1 THR 518.A OG1 no hydrogen 2.837 N/A ARG 479.A NH2 ASN 481.A OD1 no hydrogen 3.499 N/A TYR 486.A N ASN 87.A OD1 no hydrogen 3.263 N/A THR 487.A OG1 SER 488.A O no hydrogen 3.397 N/A SER 493.A OG SER 495.A O no hydrogen 2.967 N/A SER 495.A N SER 493.A OG no hydrogen 3.363 N/A ASN 501.A N VAL 505.A O no hydrogen 3.223 N/A GLY 504.A N ASN 501.A O no hydrogen 3.095 N/A VAL 505.A N ASN 501.A OD1 no hydrogen 2.640 N/A THR 514.A N ASP 396.A OD1 no hydrogen 3.292 N/A THR 514.A N ASP 396.A OD2 no hydrogen 2.671 N/A THR 514.A OG1 ASP 396.A OD1 no hydrogen 3.084 N/A THR 514.A OG1 VAL 397.A O no hydrogen 2.381 N/A ARG 515.A NH2 ASN 394.A O no hydrogen 3.152 N/A THR 518.A OG1 GLU 483.A OE1 no hydrogen 3.290 N/A THR 518.A OG1 GLU 483.A OE2 no hydrogen 3.472 N/A ARG 519.A N ALA 211.A O no hydrogen 2.864 N/A