Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6v18_E.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 1.A N THR 24.A OG1 no hydrogen 2.832 N/A PHE 3.A N LYS 22.A O no hydrogen 2.631 N/A GLN 4.A NE2 TYR 87.A O no hydrogen 2.856 N/A GLN 4.A NE2 THR 107.A OG1 no hydrogen 3.323 N/A THR 5.A N ASN 20.A O no hydrogen 2.711 N/A TYR 8.A OH GLU 154.A OE2 no hydrogen 2.985 N/A HIS 9.A N ARG 108.A O no hydrogen 2.875 N/A THR 11.A N SER 110.A O no hydrogen 3.048 N/A VAL 13.A N LEU 112.A O no hydrogen 2.845 N/A GLY 14.A N VAL 79.A O no hydrogen 2.824 N/A ASN 15.A N GLN 12.A O no hydrogen 3.163 N/A ASN 15.A ND2 THR 11.A OG1 no hydrogen 2.677 N/A VAL 17.A N ILE 76.A O no hydrogen 3.164 N/A PHE 19.A N LEU 74.A O no hydrogen 2.666 N/A ASN 20.A N THR 5.A O no hydrogen 2.708 N/A CYS 21.A SG PHE 3.A O no hydrogen 3.427 N/A CYS 21.A SG LYS 22.A O no hydrogen 3.829 N/A LYS 22.A N PHE 3.A O no hydrogen 2.607 N/A GLN 23.A N ALA 70.A O no hydrogen 2.887 N/A GLN 23.A NE2 HIS 27.A O no hydrogen 2.789 N/A GLN 23.A NE2 LYS 69.A O no hydrogen 3.060 N/A THR 24.A N ALA 1.A O no hydrogen 2.948 N/A THR 24.A OG1 ALA 1.A O no hydrogen 3.362 N/A LEU 25.A N GLN 23.A OE1 no hydrogen 3.085 N/A HIS 27.A N GLN 23.A OE1 no hydrogen 3.251 N/A HIS 27.A ND1 SER 91.A OG no hydrogen 2.705 N/A ASP 28.A N LEU 93.A O no hydrogen 2.946 N/A THR 29.A N SER 92.A O no hydrogen 3.204 N/A MET 30.A N TYR 47.A O no hydrogen 2.919 N/A TYR 31.A N ALA 90.A O no hydrogen 2.653 N/A TYR 31.A OH SER 92.A OG no hydrogen 2.652 N/A TRP 32.A N PHE 45.A O no hydrogen 3.041 N/A TYR 33.A N LEU 88.A O no hydrogen 2.729 N/A LYS 34.A N LYS 42.A O no hydrogen 2.927 N/A LYS 34.A NZ GLU 82.A O no hydrogen 2.900 N/A GLN 35.A N VAL 86.A O no hydrogen 2.718 N/A ASP 36.A N LEU 40.A O no hydrogen 3.115 N/A LYS 39.A N ASP 36.A O no hydrogen 2.802 N/A LEU 40.A N ASP 36.A OD1 no hydrogen 3.002 N/A LYS 42.A N LYS 34.A O no hydrogen 2.981 N/A MET 44.A N TRP 32.A O no hydrogen 2.874 N/A PHE 45.A N TRP 32.A O no hydrogen 3.276 N/A SER 46.A N VAL 54.A O no hydrogen 2.928 N/A TYR 47.A N MET 30.A O no hydrogen 2.761 N/A ASN 48.A N GLN 51.A O no hydrogen 2.687 N/A ASN 48.A ND2 THR 29.A OG1 no hydrogen 2.740 N/A ASN 49.A N ASP 28.A O no hydrogen 2.942 N/A GLN 51.A N ASN 48.A O no hydrogen 3.064 N/A ILE 53.A N SER 46.A O no hydrogen 2.863 N/A VAL 54.A N SER 46.A O no hydrogen 3.332 N/A GLU 56.A N MET 44.A O no hydrogen 2.884 N/A THR 57.A N ASN 55.A O no hydrogen 2.779 N/A VAL 58.A N ASN 55.A OD1 no hydrogen 2.869 N/A ARG 61.A NE ASP 83.A OD2 no hydrogen 3.018 N/A ARG 61.A NH1 ASP 83.A OD1 no hydrogen 2.827 N/A ARG 61.A NH1 ASP 83.A OD2 no hydrogen 3.477 N/A PHE 62.A N PRO 59.A O no hydrogen 2.875 N/A SER 63.A N ARG 75.A O no hydrogen 2.608 N/A GLN 65.A N ASN 73.A O no hydrogen 2.934 N/A SER 66.A OG ASP 68.A O no hydrogen 2.929 N/A SER 66.A OG HIS 71.A O no hydrogen 2.769 N/A LYS 69.A NZ HIS 27.A O no hydrogen 3.182 N/A LYS 69.A NZ ASP 28.A OD1 no hydrogen 3.081 N/A ALA 70.A N ASP 68.A OD2 no hydrogen 3.063 N/A HIS 71.A N ASP 68.A O no hydrogen 2.740 N/A HIS 71.A ND1 ASP 68.A OD2 no hydrogen 3.179 N/A LEU 72.A N CYS 21.A O no hydrogen 3.039 N/A ASN 73.A N GLN 65.A O no hydrogen 2.820 N/A ASN 73.A ND2 GLN 65.A OE1 no hydrogen 3.336 N/A LEU 74.A N PHE 19.A O no hydrogen 2.921 N/A ARG 75.A N SER 63.A O no hydrogen 2.873 N/A ARG 75.A NH1 GLU 16.A OE1 no hydrogen 2.356 N/A ILE 76.A N VAL 17.A O no hydrogen 2.823 N/A LYS 77.A N ARG 61.A O no hydrogen 2.659 N/A LYS 77.A NZ ARG 60.A O no hydrogen 3.554 N/A SER 78.A OG GLY 14.A O no hydrogen 3.385 N/A VAL 79.A N ASN 15.A O no hydrogen 2.842 N/A GLU 80.A N ASP 83.A OD2 no hydrogen 2.664 N/A GLU 82.A N GLU 82.A OE1 no hydrogen 2.778 N/A ASP 83.A N GLU 80.A O no hydrogen 2.789 N/A SER 84.A N PRO 81.A O no hydrogen 3.061 N/A SER 84.A OG PRO 81.A O no hydrogen 3.049 N/A ALA 85.A N LEU 109.A O no hydrogen 2.914 N/A VAL 86.A N GLN 35.A O no hydrogen 2.906 N/A TYR 87.A N THR 107.A O no hydrogen 2.818 N/A TYR 87.A OH ASP 83.A O no hydrogen 2.568 N/A LEU 88.A N TYR 33.A O no hydrogen 2.650 N/A CYS 89.A N GLN 4.A OE1 no hydrogen 2.997 N/A CYS 89.A SG TYR 31.A O no hydrogen 3.852 N/A CYS 89.A SG ALA 90.A O no hydrogen 3.991 N/A ALA 90.A N TYR 31.A O no hydrogen 2.991 N/A SER 91.A N TYR 102.A O no hydrogen 2.970 N/A SER 91.A OG HIS 27.A ND1 no hydrogen 2.705 N/A SER 92.A N THR 29.A O no hydrogen 2.760 N/A SER 92.A OG TYR 31.A OH no hydrogen 2.652 N/A SER 92.A OG ASP 94.A O no hydrogen 2.635 N/A GLY 96.A N ASP 94.A OD1 no hydrogen 3.085 N/A ASN 99.A N GLY 96.A O no hydrogen 3.297 N/A ASN 99.A ND2 ASP 94.A O no hydrogen 2.902 N/A ASN 99.A ND2 ASP 94.A OD1 no hydrogen 2.497 N/A TYR 102.A N SER 91.A O no hydrogen 2.891 N/A GLY 104.A N CYS 89.A O no hydrogen 2.708 N/A GLY 106.A N GLN 4.A OE1 no hydrogen 2.856 N/A THR 107.A N TYR 87.A O no hydrogen 2.869 N/A THR 107.A OG1 PRO 6.A O no hydrogen 2.621 N/A ARG 108.A N ASN 7.A O no hydrogen 2.836 N/A LEU 109.A N ALA 85.A O no hydrogen 2.770 N/A SER 110.A N HIS 9.A O no hydrogen 2.846 N/A VAL 111.A N SER 84.A OG no hydrogen 2.733 N/A LEU 112.A N THR 11.A O no hydrogen 2.888 N/A LEU 115.A N GLN 12.A OE1 no hydrogen 3.479 N/A ASN 116.A N ASP 114.A OD1 no hydrogen 3.118 N/A LYS 117.A N ASP 114.A O no hydrogen 2.911 N/A VAL 118.A N LEU 115.A O no hydrogen 3.159 N/A PHE 119.A N PHE 149.A O no hydrogen 2.880 N/A GLU 122.A N THR 146.A O no hydrogen 2.827 N/A ALA 124.A N LEU 144.A O no hydrogen 2.876 N/A PHE 126.A N VAL 142.A O no hydrogen 2.647 N/A ALA 131.A N SER 129.A OG no hydrogen 2.971 N/A GLU 132.A N SER 129.A OG no hydrogen 3.358 N/A ILE 133.A N SER 129.A O no hydrogen 3.233 N/A SER 134.A N GLU 130.A O no hydrogen 3.134 N/A SER 134.A OG GLU 130.A O no hydrogen 3.241 N/A SER 134.A OG ALA 131.A O no hydrogen 3.445 N/A HIS 135.A N ALA 131.A O no hydrogen 2.939 N/A HIS 135.A N GLU 132.A O no hydrogen 3.222 N/A THR 136.A N GLU 132.A O no hydrogen 2.755 N/A THR 136.A OG1 GLU 132.A O no hydrogen 2.830 N/A GLN 137.A N ILE 133.A O no hydrogen 2.858 N/A LYS 138.A N THR 136.A OG1 no hydrogen 3.125 N/A ALA 139.A N VAL 194.A O no hydrogen 2.769 N/A THR 140.A N GLU 132.A OE2 no hydrogen 2.935 N/A THR 140.A OG1 GLU 132.A OE1 no hydrogen 2.478 N/A THR 140.A OG1 GLU 132.A OE2 no hydrogen 3.459 N/A LEU 141.A N LEU 192.A O no hydrogen 2.666 N/A VAL 142.A N PHE 126.A O no hydrogen 3.131 N/A CYS 143.A N SER 190.A O no hydrogen 2.837 N/A CYS 143.A SG ALA 124.A O no hydrogen 3.944 N/A LEU 144.A N ALA 124.A O no hydrogen 2.711 N/A ALA 145.A N LEU 188.A O no hydrogen 2.747 N/A THR 146.A N GLU 122.A O no hydrogen 2.801 N/A THR 146.A OG1 GLU 122.A O no hydrogen 3.345 N/A PHE 148.A N TYR 186.A O no hydrogen 3.206 N/A PHE 149.A N PHE 119.A O no hydrogen 2.932 N/A GLU 154.A N GLN 211.A O no hydrogen 2.943 N/A SER 156.A N GLN 209.A O no hydrogen 2.811 N/A TRP 157.A NE1 SER 190.A OG no hydrogen 2.895 N/A TRP 158.A N ARG 207.A O no hydrogen 2.825 N/A TRP 158.A NE1 SER 156.A OG no hydrogen 2.858 N/A VAL 159.A N LYS 162.A O no hydrogen 2.801 N/A ASN 160.A N HIS 205.A O no hydrogen 2.768 N/A ASN 160.A ND2 ASN 204.A OD1 no hydrogen 2.914 N/A LYS 162.A N VAL 159.A O no hydrogen 3.065 N/A VAL 164.A N TRP 157.A O no hydrogen 3.089 N/A CYS 169.A N ARG 191.A O no hydrogen 2.956 N/A THR 170.A OG1 SER 190.A OG no hydrogen 2.527 N/A ASP 171.A N SER 189.A O no hydrogen 3.027 N/A LEU 175.A N ALA 187.A O no hydrogen 2.886 N/A LYS 176.A NZ LEU 181.A O no hydrogen 2.929 N/A GLU 177.A N ARG 185.A O no hydrogen 2.938 N/A GLN 178.A N SER 184.A OG no hydrogen 2.963 N/A LEU 181.A N GLN 178.A O no hydrogen 3.141 N/A SER 184.A N LEU 181.A O no hydrogen 3.154 N/A SER 184.A OG GLN 178.A O no hydrogen 3.313 N/A SER 184.A OG ARG 185.A O no hydrogen 2.841 N/A ARG 185.A NE GLY 147.A O no hydrogen 2.812 N/A ARG 185.A NH2 GLY 147.A O no hydrogen 3.093 N/A TYR 186.A N PHE 148.A O no hydrogen 2.651 N/A ALA 187.A N LEU 175.A O no hydrogen 2.784 N/A LEU 188.A N ALA 145.A O no hydrogen 2.567 N/A SER 189.A N ASP 171.A OD2 no hydrogen 3.030 N/A SER 189.A OG ASP 171.A OD1 no hydrogen 3.011 N/A SER 189.A OG ASP 171.A OD2 no hydrogen 2.663 N/A SER 190.A N CYS 143.A O no hydrogen 2.984 N/A SER 190.A OG CYS 169.A O no hydrogen 3.289 N/A SER 190.A OG THR 170.A OG1 no hydrogen 2.527 N/A ARG 191.A N CYS 169.A O no hydrogen 2.754 N/A ARG 191.A NH2 ASP 171.A OD1 no hydrogen 2.532 N/A LEU 192.A N LEU 141.A O no hydrogen 2.814 N/A ARG 193.A N GLY 167.A O no hydrogen 2.795 N/A ARG 193.A NE GLU 132.A OE1 no hydrogen 3.018 N/A ARG 193.A NH1 GLU 132.A OE1 no hydrogen 2.900 N/A VAL 194.A N ALA 139.A O no hydrogen 2.947 N/A ALA 196.A N GLN 137.A O no hydrogen 2.934 N/A PHE 198.A N SER 195.A OG no hydrogen 3.313 N/A TRP 199.A N SER 195.A O no hydrogen 3.026 N/A GLN 200.A N ALA 196.A O no hydrogen 2.803 N/A ASN 201.A N PHE 198.A O no hydrogen 3.373 N/A ARG 203.A N ASN 201.A OD1 no hydrogen 3.045 N/A ASN 204.A N ASN 201.A O no hydrogen 2.957 N/A ASN 204.A ND2 PHE 198.A O no hydrogen 2.813 N/A HIS 205.A N ASN 160.A OD1 no hydrogen 2.584 N/A HIS 205.A NE2 GLU 236.A OE2 no hydrogen 2.705 N/A PHE 206.A N ALA 237.A O no hydrogen 2.727 N/A ARG 207.A N TRP 158.A O no hydrogen 2.759 N/A ARG 207.A NH2 GLN 209.A OE1 no hydrogen 2.610 N/A ARG 207.A NH2 SER 234.A OG no hydrogen 3.165 N/A CYS 208.A N ALA 235.A O no hydrogen 2.705 N/A GLN 209.A N SER 156.A O no hydrogen 2.746 N/A VAL 210.A N VAL 233.A O no hydrogen 2.832 N/A GLN 211.A N GLU 154.A O no hydrogen 2.806 N/A GLN 211.A NE2 PHE 212.A O no hydrogen 3.327 N/A PHE 212.A N GLN 231.A O no hydrogen 2.655 N/A TYR 213.A N HIS 152.A O no hydrogen 2.903 N/A TYR 213.A OH GLU 154.A OE1 no hydrogen 2.900 N/A GLY 214.A N THR 230.A OG1 no hydrogen 2.925 N/A LEU 215.A N PRO 228.A O no hydrogen 3.080 N/A SER 216.A N ASP 219.A OD2 no hydrogen 2.987 N/A SER 216.A OG ASP 219.A OD2 no hydrogen 3.399 N/A ASP 219.A N SER 216.A O no hydrogen 3.270 N/A TRP 221.A NE1 ARG 225.A O no hydrogen 2.648 N/A ARG 225.A NH1 VAL 118.A O no hydrogen 2.911 N/A ARG 225.A NH2 ASN 116.A O no hydrogen 2.780 N/A ARG 225.A NH2 VAL 118.A O no hydrogen 2.683 N/A LYS 227.A NZ ASP 219.A O no hydrogen 3.464 N/A VAL 229.A N LYS 227.A O no hydrogen 2.741 N/A THR 230.A N LEU 215.A O no hydrogen 2.979 N/A THR 230.A OG1 GLY 214.A O no hydrogen 3.394 N/A GLN 231.A N PHE 212.A O no hydrogen 2.944 N/A GLN 231.A NE2 VAL 229.A O no hydrogen 2.916 N/A VAL 233.A N VAL 210.A O no hydrogen 2.923 N/A ALA 235.A N CYS 208.A O no hydrogen 2.880 N/A ALA 237.A N PHE 206.A O no hydrogen 2.716 N/A GLY 239.A N ASN 204.A O no hydrogen 2.838 N/A ARG 240.A N TRP 199.A O no hydrogen 3.111 N/A