Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6xbi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A N ASN 215.A O no hydrogen 3.420 N/A SER 2.A OG ASN 215.A OD1 no hydrogen 3.022 N/A ARG 5.A N GLN 300.A OE1 no hydrogen 2.883 N/A PHE 9.A N SER 114.A OG no hydrogen 2.817 N/A SER 11.A OG GLU 15.A OE2 no hydrogen 2.636 N/A LYS 13.A NZ GLN 307.A OE1 no hydrogen 2.769 N/A VAL 14.A N SER 11.A O no hydrogen 2.912 N/A GLU 15.A N SER 11.A O no hydrogen 2.998 N/A GLY 16.A N GLY 12.A O no hydrogen 3.372 N/A CYS 17.A N VAL 14.A O no hydrogen 2.898 N/A CYS 17.A SG LYS 13.A O no hydrogen 3.532 N/A MET 18.A N GLU 15.A O no hydrogen 3.324 N/A VAL 19.A N GLY 30.A O no hydrogen 2.886 N/A GLN 20.A N GLN 70.A O no hydrogen 2.850 N/A VAL 21.A N LEU 28.A O no hydrogen 2.942 N/A THR 22.A N LEU 68.A O no hydrogen 2.989 N/A THR 22.A OG1 THR 27.A OG1 no hydrogen 3.247 N/A CYS 23.A N THR 26.A O no hydrogen 2.998 N/A CYS 23.A SG ASN 66.A O no hydrogen 3.743 N/A THR 26.A N CYS 23.A O no hydrogen 3.030 N/A THR 27.A OG1 THR 22.A OG1 no hydrogen 3.247 N/A LEU 28.A N VAL 21.A O no hydrogen 2.957 N/A ASN 29.A N CYS 146.A O no hydrogen 2.945 N/A ASN 29.A ND2 CYS 118.A O no hydrogen 2.887 N/A ASN 29.A ND2 GLY 144.A O no hydrogen 3.063 N/A ASN 29.A ND2 CYS 146.A O no hydrogen 2.979 N/A GLY 30.A N VAL 19.A O no hydrogen 2.826 N/A LEU 31.A N TYR 38.A O no hydrogen 2.879 N/A TRP 32.A N CYS 17.A O no hydrogen 2.607 N/A TRP 32.A NE1 THR 94.A O no hydrogen 3.153 N/A LEU 33.A N VAL 36.A O no hydrogen 3.043 N/A ASP 34.A N THR 99.A OG1 no hydrogen 3.057 N/A VAL 36.A N LEU 33.A O no hydrogen 2.997 N/A VAL 37.A N LEU 90.A O no hydrogen 2.866 N/A TYR 38.A N LEU 31.A O no hydrogen 2.915 N/A CYS 39.A N LEU 88.A O no hydrogen 3.091 N/A CYS 39.A SG PRO 40.A O no hydrogen 3.729 N/A ARG 41.A N CYS 86.A O no hydrogen 3.038 N/A ARG 41.A NE ASP 188.A OD2 no hydrogen 2.776 N/A ARG 41.A NH2 ASP 188.A OD1 no hydrogen 3.001 N/A VAL 43.A N PRO 40.A O no hydrogen 3.126 N/A ILE 44.A N ARG 41.A O no hydrogen 3.089 N/A CYS 45.A N HIS 42.A O no hydrogen 3.009 N/A CYS 45.A SG HIS 42.A O no hydrogen 3.642 N/A CYS 45.A SG TYR 55.A OH no hydrogen 3.523 N/A ASP 49.A N THR 46.A O no hydrogen 3.084 N/A TYR 55.A OH ASP 188.A O no hydrogen 2.659 N/A GLU 56.A N.B GLU 56.A OE1.B no hydrogen 2.917 N/A ASP 57.A N ASN 54.A OD1 no hydrogen 3.056 N/A LEU 58.A N ASN 54.A O no hydrogen 2.741 N/A LEU 59.A N TYR 55.A O no hydrogen 2.881 N/A ILE 60.A N GLU 56.A O.A no hydrogen 3.103 N/A ILE 60.A N GLU 56.A O.B no hydrogen 3.208 N/A LYS 62.A N LEU 59.A O no hydrogen 3.094 N/A SER 63.A N ASN 66.A OD1 no hydrogen 2.755 N/A ASN 66.A N SER 63.A O no hydrogen 3.046 N/A PHE 67.A N ASN 64.A O no hydrogen 3.129 N/A LEU 68.A N THR 22.A O no hydrogen 3.042 N/A GLN 70.A N GLN 20.A O no hydrogen 2.880 N/A ALA 71.A N VAL 74.A O no hydrogen 3.040 N/A LEU 76.A N VAL 69.A O no hydrogen 2.716 N/A ILE 79.A N LYS 91.A O no hydrogen 2.860 N/A GLY 80.A N LYS 91.A O no hydrogen 3.238 N/A HIS 81.A ND1 ASN 64.A OD1 no hydrogen 2.647 N/A SER 82.A N LYS 89.A O no hydrogen 2.998 N/A GLN 84.A N VAL 87.A O no hydrogen 2.816 N/A ASN 85.A ND2 GLU 179.A O no hydrogen 2.892 N/A CYS 86.A N GLY 180.A O no hydrogen 2.841 N/A CYS 86.A SG ASP 188.A OD1 no hydrogen 3.757 N/A CYS 86.A SG ASP 188.A OD2 no hydrogen 3.707 N/A VAL 87.A N GLN 84.A O no hydrogen 2.994 N/A LEU 88.A N CYS 39.A O no hydrogen 2.837 N/A LYS 89.A N SER 82.A O no hydrogen 2.937 N/A LYS 89.A NZ GLN 84.A OE1 no hydrogen 3.178 N/A LEU 90.A N VAL 37.A O no hydrogen 2.758 N/A VAL 92.A N ASP 35.A O no hydrogen 2.816 N/A ASP 93.A N ARG 77.A O no hydrogen 3.118 N/A THR 94.A OG1 ASP 93.A OD1 no hydrogen 2.906 N/A ASN 96.A N ASP 34.A O no hydrogen 2.957 N/A ASN 96.A ND2 GLY 16.A O no hydrogen 2.907 N/A ASN 96.A ND2 TRP 32.A O no hydrogen 2.807 N/A LYS 98.A N ASN 96.A OD1 no hydrogen 2.897 N/A THR 99.A N ASN 96.A O no hydrogen 3.073 N/A THR 99.A OG1 ASN 96.A O no hydrogen 2.613 N/A LYS 103.A N VAL 158.A O no hydrogen 3.042 N/A VAL 105.A N PHE 160.A O no hydrogen 2.923 N/A ARG 106.A NH1 ASP 177.A OD2 no hydrogen 2.982 N/A ARG 106.A NH1 ASN 181.A O no hydrogen 3.148 N/A ARG 106.A NH1 PHE 182.A O no hydrogen 3.471 N/A ARG 106.A NH2 PHE 182.A O no hydrogen 2.856 N/A ILE 107.A N TYR 183.A OH no hydrogen 3.002 N/A GLN 108.A N GLN 111.A OE1 no hydrogen 2.836 N/A GLY 110.A N MET 131.A O no hydrogen 2.736 N/A GLN 111.A N GLN 108.A O no hydrogen 3.131 N/A THR 112.A OG1 ASP 296.A OD1 no hydrogen 3.267 N/A THR 112.A OG1 ASP 296.A OD2 no hydrogen 2.643 N/A PHE 113.A N CYS 129.A O.A no hydrogen 2.787 N/A PHE 113.A N CYS 129.A O.B no hydrogen 3.002 N/A SER 114.A N PHE 151.A O no hydrogen 2.828 N/A SER 114.A OG GLN 128.A OE1 no hydrogen 2.615 N/A VAL 115.A N TYR 127.A O no hydrogen 2.731 N/A LEU 116.A N VAL 149.A O no hydrogen 3.070 N/A ALA 117.A N GLY 125.A O no hydrogen 2.813 N/A CYS 118.A N SER 148.A OG no hydrogen 2.853 N/A CYS 118.A SG LEU 116.A O no hydrogen 3.612 N/A TYR 119.A N SER 122.A O no hydrogen 3.081 N/A ASN 120.A ND2 GLN 20.A OE1 no hydrogen 3.302 N/A GLY 121.A N ASN 29.A OD1 no hydrogen 2.866 N/A SER 122.A N TYR 119.A O no hydrogen 2.930 N/A SER 124.A N ALA 117.A O no hydrogen 2.790 N/A SER 124.A OG ALA 117.A O no hydrogen 3.389 N/A GLY 125.A N ALA 117.A O no hydrogen 3.314 N/A TYR 127.A N VAL 115.A O no hydrogen 3.168 N/A TYR 127.A OH SER 140.A O no hydrogen 3.068 N/A CYS 129.A N.A PHE 113.A O no hydrogen 2.820 N/A CYS 129.A N.B PHE 113.A O no hydrogen 2.753 N/A MET 131.A N GLN 111.A O no hydrogen 2.986 N/A ARG 132.A N THR 136.A O no hydrogen 2.906 N/A ARG 132.A NE ASP 198.A OD1.A no hydrogen 3.128 N/A ARG 132.A NH1 ASP 290.A OD1 no hydrogen 2.906 N/A ARG 132.A NH1 ASP 290.A OD2 no hydrogen 3.368 N/A ARG 132.A NH1 GLU 291.A OE2 no hydrogen 2.834 N/A ARG 132.A NH2 THR 199.A O.A no hydrogen 3.115 N/A ARG 132.A NH2 THR 199.A O.B no hydrogen 3.105 N/A ARG 132.A NH2 ASP 290.A OD2 no hydrogen 2.659 N/A ASN 134.A ND2 GLY 196.A O no hydrogen 2.889 N/A PHE 135.A N ARG 132.A O no hydrogen 2.845 N/A THR 136.A N ASN 134.A OD1 no hydrogen 3.197 N/A THR 136.A OG1 ASN 134.A OD1 no hydrogen 2.678 N/A ILE 137.A N HIS 173.A O no hydrogen 2.903 N/A GLY 139.A N HIS 173.A ND1 no hydrogen 3.147 N/A SER 140.A N TYR 127.A OH no hydrogen 2.907 N/A LEU 142.A N TYR 119.A OH no hydrogen 2.830 N/A SER 145.A N LEU 142.A O no hydrogen 2.892 N/A SER 145.A OG LEU 142.A O no hydrogen 2.618 N/A CYS 146.A SG HIS 42.A NE2 no hydrogen 3.641 N/A CYS 146.A SG HIS 165.A O no hydrogen 3.201 N/A GLY 147.A N HIS 164.A O no hydrogen 2.940 N/A SER 148.A N SER 145.A O no hydrogen 2.997 N/A SER 148.A OG SER 145.A O no hydrogen 2.770 N/A GLY 150.A N TYR 162.A O no hydrogen 2.823 N/A PHE 151.A N SER 114.A O no hydrogen 2.868 N/A ASN 152.A N SER 159.A O no hydrogen 2.995 N/A ASN 152.A ND2 THR 112.A O no hydrogen 3.176 N/A ASP 154.A N CYS 157.A O no hydrogen 3.061 N/A CYS 157.A N ASP 154.A O no hydrogen 2.936 N/A CYS 157.A SG VAL 158.A O no hydrogen 3.980 N/A VAL 158.A N LYS 101.A O no hydrogen 2.997 N/A SER 159.A N ASN 152.A O no hydrogen 2.806 N/A PHE 160.A N LYS 103.A O no hydrogen 2.959 N/A CYS 161.A N GLY 150.A O no hydrogen 2.932 N/A TYR 162.A N GLY 150.A O no hydrogen 3.239 N/A TYR 162.A OH HIS 164.A ND1 no hydrogen 2.892 N/A MET 163.A N THR 176.A O no hydrogen 2.723 N/A HIS 164.A N SER 148.A O no hydrogen 2.899 N/A HIS 164.A ND1 TYR 162.A OH no hydrogen 2.892 N/A HIS 165.A N ALA 174.A O no hydrogen 3.253 N/A HIS 165.A NE2 THR 176.A OG1 no hydrogen 2.977 N/A MET 166.A N ALA 174.A O no hydrogen 2.972 N/A LEU 168.A N VAL 172.A O no hydrogen 2.823 N/A GLY 171.A N LEU 168.A O no hydrogen 2.807 N/A HIS 173.A N ILE 137.A O no hydrogen 2.785 N/A HIS 173.A NE2 GLU 167.A OE2 no hydrogen 2.877 N/A ALA 174.A N MET 166.A O no hydrogen 2.928 N/A THR 176.A N MET 163.A O no hydrogen 2.993 N/A THR 176.A OG1 HIS 165.A NE2 no hydrogen 2.977 N/A THR 176.A OG1 ASP 177.A O no hydrogen 2.868 N/A ASP 177.A N ASN 181.A O no hydrogen 2.954 N/A GLU 179.A N ASP 177.A OD1 no hydrogen 3.036 N/A GLY 180.A N ASP 177.A O no hydrogen 3.014 N/A ASN 181.A N ASP 177.A OD1 no hydrogen 3.102 N/A TYR 183.A N GLY 175.A O no hydrogen 2.981 N/A TYR 183.A OH CYS 161.A O no hydrogen 2.634 N/A VAL 187.A N GLN 193.A OE1 no hydrogen 2.973 N/A ARG 189.A NH1 LEU 51.A O no hydrogen 3.212 N/A GLN 190.A N MET 50.A O no hydrogen 2.784 N/A GLN 193.A NE2 VAL 187.A O no hydrogen 3.031 N/A GLN 193.A NE2 THR 191.A O no hydrogen 3.410 N/A THR 200.A N ASN 239.A O no hydrogen 2.896 N/A ILE 201.A N ASP 290.A OD2 no hydrogen 2.861 N/A THR 202.A OG1 THR 200.A O no hydrogen 3.562 N/A THR 202.A OG1 GLU 241.A O no hydrogen 2.677 N/A ASN 204.A ND2 GLY 110.A O no hydrogen 3.011 N/A ASN 204.A ND2 ASP 290.A O no hydrogen 2.945 N/A VAL 205.A N ILE 201.A O no hydrogen 3.102 N/A LEU 206.A N THR 202.A O no hydrogen 3.029 N/A ALA 207.A N VAL 203.A O no hydrogen 3.000 N/A TRP 208.A N ASN 204.A O no hydrogen 2.970 N/A LEU 209.A N VAL 205.A O no hydrogen 3.000 N/A TYR 210.A N LEU 206.A O no hydrogen 3.017 N/A TYR 210.A OH ILE 260.A O no hydrogen 2.853 N/A ALA 211.A N ALA 207.A O no hydrogen 2.880 N/A ALA 212.A N TRP 208.A O no hydrogen 2.870 N/A VAL 213.A N LEU 209.A O no hydrogen 3.084 N/A ILE 214.A N TYR 210.A O no hydrogen 2.975 N/A ASN 215.A N ALA 211.A O no hydrogen 3.065 N/A ASN 215.A N ALA 212.A O no hydrogen 3.101 N/A ASN 215.A ND2 ALA 211.A O no hydrogen 2.906 N/A GLY 216.A N VAL 213.A O no hydrogen 2.996 N/A ASP 217.A N ALA 212.A O no hydrogen 2.841 N/A TRP 219.A NE1 THR 281.A O no hydrogen 2.919 N/A LEU 221.A N ARG 218.A O no hydrogen 2.966 N/A PHE 224.A N ASN 222.A OD1 no hydrogen 3.122 N/A THR 225.A OG1 THR 226.A O no hydrogen 3.330 N/A THR 225.A OG1 ASP 264.A OD1 no hydrogen 3.156 N/A THR 226.A OG1 THR 227.A O no hydrogen 3.044 N/A ASP 230.A N THR 227.A OG1 no hydrogen 2.975 N/A PHE 231.A N THR 227.A O no hydrogen 2.982 N/A ASN 232.A N LEU 228.A O no hydrogen 2.930 N/A ASN 232.A ND2 LEU 243.A O no hydrogen 2.962 N/A LEU 233.A N ASN 229.A O no hydrogen 3.293 N/A ALA 235.A N PHE 231.A O no hydrogen 2.876 N/A MET 236.A N ASN 232.A O no hydrogen 2.988 N/A TYR 238.A N ALA 235.A O no hydrogen 2.933 N/A ASN 239.A N MET 236.A O no hydrogen 3.257 N/A TYR 240.A N ALA 235.A O no hydrogen 3.049 N/A GLU 241.A N THR 200.A O no hydrogen 2.980 N/A LEU 243.A N ASN 232.A OD1 no hydrogen 2.832 N/A THR 244.A N HIS 247.A ND1 no hydrogen 3.083 N/A GLN 245.A NE2 ASP 249.A OD1 no hydrogen 2.966 N/A HIS 247.A N THR 244.A OG1 no hydrogen 3.199 N/A VAL 248.A N THR 244.A O no hydrogen 3.013 N/A ASP 249.A N GLN 245.A O no hydrogen 2.772 N/A ILE 250.A N ASP 246.A O no hydrogen 2.933 N/A LEU 251.A N HIS 247.A O no hydrogen 2.947 N/A GLY 252.A N ASP 249.A O no hydrogen 3.092 N/A SER 255.A N.A LEU 251.A O no hydrogen 3.066 N/A SER 255.A N.B LEU 251.A O no hydrogen 3.073 N/A SER 255.A OG.A ILE 260.A O no hydrogen 2.623 N/A SER 255.A OG.B GLY 252.A O no hydrogen 2.919 N/A ALA 256.A N GLY 252.A O no hydrogen 2.926 N/A GLN 257.A N PRO 253.A O no hydrogen 2.986 N/A THR 258.A N LEU 254.A O no hydrogen 3.010 N/A THR 258.A OG1 LEU 254.A O no hydrogen 2.888 N/A THR 258.A OG1 SER 255.A O.A no hydrogen 3.415 N/A THR 258.A OG1 SER 255.A O.B no hydrogen 3.524 N/A GLY 259.A N ALA 256.A O no hydrogen 3.256 N/A ILE 260.A N THR 258.A OG1 no hydrogen 3.297 N/A MET 265.A N ALA 261.A O no hydrogen 3.030 N/A CYS 266.A N VAL 262.A O no hydrogen 2.917 N/A CYS 266.A SG VAL 262.A O no hydrogen 3.440 N/A ALA 267.A N LEU 263.A O no hydrogen 3.109 N/A SER 268.A N ASP 264.A O no hydrogen 3.079 N/A SER 268.A OG PHE 220.A O no hydrogen 3.105 N/A LEU 269.A N MET 265.A O no hydrogen 2.841 N/A LYS 270.A N CYS 266.A O no hydrogen 2.858 N/A GLU 271.A N ALA 267.A O no hydrogen 3.174 N/A LEU 272.A N SER 268.A O no hydrogen 3.007 N/A LEU 273.A N LEU 269.A O no hydrogen 2.879 N/A GLN 274.A N LYS 270.A O no hydrogen 2.911 N/A ASN 275.A N GLU 271.A O no hydrogen 2.899 N/A GLY 276.A N LEU 272.A O no hydrogen 2.904 N/A ARG 280.A N MET 277.A O no hydrogen 3.137 N/A ARG 280.A NE MET 277.A O no hydrogen 2.979 N/A ARG 280.A NH1 MET 277.A O no hydrogen 3.342 N/A ILE 282.A N SER 285.A O no hydrogen 2.946 N/A LEU 283.A N ASP 217.A OD2.A no hydrogen 3.076 N/A SER 285.A N ILE 282.A O no hydrogen 2.842 N/A SER 285.A OG LEU 287.A O no hydrogen 2.762 N/A SER 285.A OG GLU 289.A OE2 no hydrogen 3.162 N/A LEU 287.A N SER 285.A OG no hydrogen 2.975 N/A THR 293.A N ASP 296.A OD2 no hydrogen 2.962 N/A ASP 296.A N THR 293.A OG1 no hydrogen 2.872 N/A VAL 297.A N THR 293.A O no hydrogen 3.063 N/A VAL 298.A N PRO 294.A O no hydrogen 3.207 N/A ARG 299.A N PHE 295.A O no hydrogen 2.929 N/A ARG 299.A NH1 ASP 296.A OD1 no hydrogen 3.020 N/A GLN 300.A N ASP 296.A O no hydrogen 3.066 N/A GLN 300.A NE2 ARG 5.A O no hydrogen 2.784 N/A CYS 301.A N VAL 297.A O no hydrogen 2.834 N/A CYS 301.A SG VAL 297.A O no hydrogen 3.313 N/A SER 302.A OG VAL 298.A O no hydrogen 3.055 N/A GLY 303.A N ARG 299.A O no hydrogen 2.924 N/A VAL 304.A N ARG 299.A O no hydrogen 3.184 N/A