Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6xd3_I.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 5.A N TYR 2.A O no hydrogen 2.577 N/A SER 5.A OG HIS 158.A NE2 no hydrogen 2.966 N/A LYS 8.A NZ HIS 3.A O no hydrogen 3.169 N/A ARG 9.A N SER 5.A O no hydrogen 3.209 N/A HIS 10.A N SER 6.A O no hydrogen 2.895 N/A THR 12.A OG1 GLN 7.A O no hydrogen 2.967 N/A THR 12.A OG1 TRP 11.A O no hydrogen 2.730 N/A PHE 13.A N LEU 202.A O no hydrogen 2.775 N/A GLN 18.A N SER 15.A O no hydrogen 2.925 N/A ALA 20.A N GLU 16.A O no hydrogen 2.941 N/A ARG 21.A N GLU 17.A O no hydrogen 2.838 N/A LEU 22.A N GLN 18.A O no hydrogen 2.916 N/A ARG 23.A N LEU 19.A O no hydrogen 2.935 N/A ARG 23.A NH1 ASP 199.A OD2 no hydrogen 2.869 N/A ARG 23.A NH2 ASP 199.A OD1 no hydrogen 3.323 N/A ARG 23.A NH2 ASP 199.A OD2 no hydrogen 2.530 N/A ALA 24.A N ALA 20.A O no hydrogen 2.876 N/A ASP 25.A N ARG 21.A O no hydrogen 2.867 N/A ALA 26.A N LEU 22.A O no hydrogen 2.918 N/A ASN 27.A N ARG 23.A O no hydrogen 2.929 N/A ASN 27.A ND2 LEU 45.A O no hydrogen 2.909 N/A ASN 27.A ND2 GLU 50.A OE2 no hydrogen 2.401 N/A ARG 28.A N ALA 24.A O no hydrogen 2.854 N/A LYS 29.A N ASP 25.A O no hydrogen 2.873 N/A PHE 30.A N ALA 26.A O no hydrogen 2.932 N/A ARG 31.A N ASN 27.A O no hydrogen 2.915 N/A ARG 31.A NH1 GLU 46.A OE2 no hydrogen 2.664 N/A CYS 32.A N ARG 28.A O no hydrogen 2.885 N/A CYS 32.A SG ARG 28.A O no hydrogen 3.479 N/A LYS 33.A N LYS 29.A O no hydrogen 2.897 N/A ALA 34.A N PHE 30.A O no hydrogen 2.887 N/A VAL 35.A N ARG 31.A O no hydrogen 2.932 N/A ALA 36.A N CYS 32.A O no hydrogen 2.743 N/A ASN 37.A N LYS 33.A O no hydrogen 2.923 N/A ASN 37.A ND2 ASN 37.A O no hydrogen 2.696 N/A PHE 44.A N ASP 41.A O no hydrogen 2.917 N/A GLU 46.A N GLU 49.A OE1 no hydrogen 2.703 N/A GLU 50.A N GLU 46.A O no hydrogen 3.037 N/A MET 51.A N PRO 47.A O no hydrogen 2.892 N/A THR 52.A N HIS 48.A O no hydrogen 2.944 N/A THR 52.A OG1 HIS 48.A O no hydrogen 3.247 N/A THR 52.A OG1 GLU 49.A O no hydrogen 2.648 N/A LEU 53.A N GLU 49.A O no hydrogen 2.945 N/A CYS 54.A N GLU 50.A O no hydrogen 2.881 N/A CYS 54.A SG GLU 50.A O no hydrogen 3.281 N/A LYS 55.A N MET 51.A O no hydrogen 2.879 N/A TYR 56.A N THR 52.A O no hydrogen 2.953 N/A TYR 57.A N LEU 53.A O no hydrogen 2.920 N/A GLU 58.A N CYS 54.A O no hydrogen 2.848 N/A LYS 59.A N LYS 55.A O no hydrogen 2.967 N/A ARG 60.A N TYR 56.A O no hydrogen 2.949 N/A LEU 61.A N TYR 57.A O no hydrogen 2.871 N/A LEU 62.A N GLU 58.A O no hydrogen 2.905 N/A GLU 63.A N LYS 59.A O no hydrogen 2.947 N/A PHE 64.A N ARG 60.A O no hydrogen 2.902 N/A CYS 65.A N LEU 61.A O no hydrogen 2.881 N/A CYS 65.A SG LEU 61.A O no hydrogen 3.235 N/A SER 66.A N LEU 62.A O no hydrogen 2.904 N/A VAL 67.A N GLU 63.A O no hydrogen 2.951 N/A PHE 68.A N CYS 65.A O no hydrogen 3.192 N/A VAL 76.A N PRO 73.A O no hydrogen 2.894 N/A VAL 77.A N PRO 73.A O no hydrogen 3.270 N/A GLY 78.A N ARG 74.A O no hydrogen 2.902 N/A THR 79.A N SER 75.A O no hydrogen 2.879 N/A THR 79.A OG1 SER 75.A O no hydrogen 2.295 N/A ALA 80.A N VAL 76.A O no hydrogen 2.876 N/A CYS 81.A N VAL 77.A O no hydrogen 2.945 N/A CYS 81.A SG VAL 77.A O no hydrogen 3.092 N/A MET 82.A N GLY 78.A O no hydrogen 2.902 N/A TYR 83.A N THR 79.A O no hydrogen 2.881 N/A TYR 83.A OH LEU 155.A O no hydrogen 2.160 N/A PHE 84.A N ALA 80.A O no hydrogen 2.906 N/A LYS 85.A N CYS 81.A O no hydrogen 2.943 N/A LYS 85.A NZ GLU 58.A OE2 no hydrogen 2.243 N/A LYS 85.A NZ ALA 196.A O no hydrogen 2.908 N/A ARG 86.A N MET 82.A O no hydrogen 2.873 N/A PHE 87.A N TYR 83.A O no hydrogen 2.869 N/A TYR 88.A N PHE 84.A O no hydrogen 2.993 N/A TYR 88.A OH TYR 96.A O no hydrogen 2.508 N/A LEU 89.A N LYS 85.A O no hydrogen 2.874 N/A ASN 91.A ND2 GLN 150.A OE1 no hydrogen 2.899 N/A VAL 93.A N GLU 50.A OE1 no hydrogen 3.156 N/A GLU 95.A N SER 92.A OG no hydrogen 2.992 N/A ARG 99.A N HIS 97.A ND1 no hydrogen 2.954 N/A ARG 99.A NH1 GLU 128.A OE2 no hydrogen 3.173 N/A ARG 99.A NH2 GLU 128.A OE2 no hydrogen 2.732 N/A ILE 101.A N HIS 97.A O no hydrogen 3.124 N/A MET 102.A N PRO 98.A O no hydrogen 2.841 N/A LEU 103.A N ARG 99.A O no hydrogen 2.988 N/A THR 104.A N ILE 100.A O no hydrogen 2.851 N/A THR 104.A OG1 ILE 100.A O no hydrogen 2.820 N/A CYS 105.A N ILE 101.A O no hydrogen 2.830 N/A CYS 105.A SG ILE 101.A O no hydrogen 3.238 N/A ALA 106.A N MET 102.A O no hydrogen 2.979 N/A PHE 107.A N LEU 103.A O no hydrogen 2.878 N/A LEU 108.A N THR 104.A O no hydrogen 2.847 N/A ALA 109.A N CYS 105.A O no hydrogen 2.871 N/A CYS 110.A N ALA 106.A O no hydrogen 2.900 N/A CYS 110.A SG ALA 106.A O no hydrogen 3.337 N/A LYS 111.A N PHE 107.A O no hydrogen 2.950 N/A LYS 111.A NZ GLU 144.A OE2 no hydrogen 3.249 N/A VAL 112.A N LEU 108.A O no hydrogen 2.827 N/A ASP 113.A N ALA 109.A O no hydrogen 3.232 N/A PHE 122.A N SER 118.A O no hydrogen 2.870 N/A VAL 123.A N SER 119.A O no hydrogen 2.965 N/A GLY 124.A N PRO 120.A O no hydrogen 2.848 N/A ASN 125.A N PHE 122.A O no hydrogen 3.092 N/A LEU 126.A N VAL 123.A O no hydrogen 2.738 N/A GLY 132.A N SER 129.A OG no hydrogen 3.206 N/A GLN 133.A N SER 129.A O no hydrogen 2.565 N/A GLN 133.A NE2 LEU 126.A O no hydrogen 3.221 N/A GLU 134.A N PRO 130.A O no hydrogen 2.885 N/A LYS 135.A N LEU 131.A O no hydrogen 2.941 N/A ALA 136.A N GLY 132.A O no hydrogen 2.871 N/A LEU 137.A N GLN 133.A O no hydrogen 2.844 N/A GLU 138.A N GLU 134.A O no hydrogen 2.914 N/A GLN 139.A N LYS 135.A O no hydrogen 2.924 N/A ILE 140.A N ALA 136.A O no hydrogen 2.884 N/A LEU 141.A N LEU 137.A O no hydrogen 2.936 N/A GLU 142.A N GLU 138.A O no hydrogen 2.908 N/A TYR 143.A N GLN 139.A O no hydrogen 2.910 N/A LEU 147.A N TYR 143.A O no hydrogen 2.887 N/A ILE 148.A N GLU 144.A O no hydrogen 2.944 N/A GLN 149.A N LEU 145.A O no hydrogen 2.884 N/A GLN 150.A N LEU 146.A O no hydrogen 2.920 N/A LEU 151.A N LEU 147.A O no hydrogen 3.001 N/A ASN 152.A N GLN 149.A O no hydrogen 2.943 N/A PHE 153.A N ILE 148.A O no hydrogen 3.203 N/A HIS 154.A N LEU 151.A O no hydrogen 3.070 N/A HIS 158.A N GLN 7.A OE1 no hydrogen 2.910 N/A ASN 159.A ND2 SER 75.A O no hydrogen 3.072 N/A PHE 164.A N PRO 160.A O no hydrogen 2.900 N/A GLU 165.A N TYR 161.A O no hydrogen 2.956 N/A GLY 166.A N ARG 162.A O no hydrogen 2.932 N/A PHE 167.A N PRO 163.A O no hydrogen 2.860 N/A LEU 168.A N PHE 164.A O no hydrogen 2.970 N/A ILE 169.A N GLU 165.A O no hydrogen 2.943 N/A ASP 170.A N GLY 166.A O no hydrogen 2.957 N/A LEU 171.A N PHE 167.A O no hydrogen 2.852 N/A LYS 172.A N LEU 168.A O no hydrogen 2.881 N/A THR 173.A N ILE 169.A O no hydrogen 2.993 N/A THR 173.A OG1 ILE 169.A O no hydrogen 3.467 N/A THR 173.A OG1 ASP 170.A O no hydrogen 3.412 N/A ARG 174.A N ASP 170.A O no hydrogen 2.870 N/A TYR 175.A N LEU 171.A O no hydrogen 3.327 N/A ARG 185.A N PRO 181.A O no hydrogen 2.901 N/A ARG 185.A NE GLU 182.A OE1 no hydrogen 3.401 N/A ARG 185.A NH1 GLU 165.A OE1 no hydrogen 3.269 N/A ARG 185.A NH1 GLU 165.A OE2 no hydrogen 2.314 N/A ARG 185.A NH2 GLU 165.A OE1 no hydrogen 2.840 N/A LYS 186.A N GLU 182.A O no hydrogen 2.951 N/A THR 187.A N ILE 183.A O no hydrogen 3.039 N/A THR 187.A OG1 ILE 183.A O no hydrogen 3.086 N/A ALA 188.A N LEU 184.A O no hydrogen 2.819 N/A ASP 189.A N ARG 185.A O no hydrogen 2.872 N/A ASP 190.A N LYS 186.A O no hydrogen 3.062 N/A PHE 191.A N THR 187.A O no hydrogen 2.945 N/A LEU 192.A N ALA 188.A O no hydrogen 2.784 N/A ASN 193.A N ASP 189.A O no hydrogen 2.979 N/A ARG 194.A N ASP 190.A O no hydrogen 3.028 N/A ILE 195.A N PHE 191.A O no hydrogen 2.862 N/A ALA 196.A N LEU 192.A O no hydrogen 2.887 N/A LEU 197.A N ASN 193.A O no hydrogen 3.048 N/A ASP 199.A N THR 198.A OG1 no hydrogen 2.540 N/A LEU 203.A N ALA 200.A O no hydrogen 3.145 N/A TYR 204.A N ALA 200.A O no hydrogen 3.001 N/A THR 205.A N GLN 208.A OE1 no hydrogen 3.020 N/A GLN 208.A N THR 205.A OG1 no hydrogen 3.158 N/A ILE 209.A N THR 205.A O no hydrogen 3.065 N/A ALA 210.A N PRO 206.A O no hydrogen 2.921 N/A LEU 211.A N SER 207.A O no hydrogen 2.907 N/A THR 212.A N GLN 208.A O no hydrogen 2.863 N/A THR 212.A OG1 GLN 208.A O no hydrogen 2.787 N/A ALA 213.A N ILE 209.A O no hydrogen 2.892 N/A ILE 214.A N ALA 210.A O no hydrogen 2.979 N/A LEU 215.A N LEU 211.A O no hydrogen 2.906 N/A SER 216.A N THR 212.A O no hydrogen 2.797 N/A SER 217.A N ALA 213.A O no hydrogen 2.935 N/A SER 217.A OG LEU 184.A O no hydrogen 3.455 N/A SER 217.A OG ALA 213.A O no hydrogen 3.150 N/A ALA 218.A N ILE 214.A O no hydrogen 2.947 N/A SER 219.A N LEU 215.A O no hydrogen 2.844 N/A ARG 220.A N SER 216.A O no hydrogen 2.878 N/A ARG 220.A NH1 SER 219.A OG no hydrogen 3.302 N/A ALA 221.A N ALA 218.A O no hydrogen 3.115 N/A GLY 222.A N SER 219.A O no hydrogen 3.053 N/A ILE 223.A N ALA 218.A O no hydrogen 2.766 N/A TYR 228.A N MET 225.A O no hydrogen 2.979 N/A SER 230.A N GLU 226.A O no hydrogen 3.330 N/A SER 230.A OG GLU 226.A O no hydrogen 3.063 N/A GLU 231.A N SER 227.A O no hydrogen 2.979 N/A SER 232.A OG TYR 228.A O no hydrogen 2.992 N/A SER 232.A OG GLU 231.A O no hydrogen 2.326 N/A LYS 236.A N SER 230.A O no hydrogen 2.821 N/A ASN 238.A N LEU 235.A O no hydrogen 3.006 N/A ARG 239.A NH2 LYS 236.A O no hydrogen 2.608 N/A THR 240.A OG1 ASN 238.A OD1 no hydrogen 3.249 N/A CYS 241.A N ASN 238.A OD1 no hydrogen 3.446 N/A LEU 242.A N ASN 238.A O no hydrogen 3.212 N/A SER 243.A N ARG 239.A O no hydrogen 2.932 N/A SER 243.A OG ARG 239.A O no hydrogen 3.130 N/A SER 243.A OG THR 240.A O no hydrogen 2.513 N/A GLN 244.A N THR 240.A O no hydrogen 2.900 N/A GLN 244.A NE2 THR 240.A O no hydrogen 2.610 N/A LEU 245.A N CYS 241.A O no hydrogen 2.879 N/A LEU 246.A N LEU 242.A O no hydrogen 3.005 N/A ASP 247.A N SER 243.A O no hydrogen 2.866 N/A ILE 248.A N GLN 244.A O no hydrogen 2.839 N/A MET 249.A N LEU 245.A O no hydrogen 2.941 N/A LYS 250.A N LEU 246.A O no hydrogen 2.922 N/A SER 251.A N ASP 247.A O no hydrogen 2.840 N/A SER 251.A OG ASP 247.A O no hydrogen 3.258 N/A SER 251.A OG ASP 247.A OD1 no hydrogen 3.367 N/A MET 252.A N ILE 248.A O no hydrogen 2.915 N/A ARG 253.A N MET 249.A O no hydrogen 2.907 N/A ASN 254.A N LYS 250.A O no hydrogen 2.940 N/A LEU 255.A N SER 251.A O no hydrogen 2.846 N/A VAL 256.A N MET 252.A O no hydrogen 2.932 N/A LYS 257.A N ARG 253.A O no hydrogen 2.917 N/A LYS 258.A N ASN 254.A O no hydrogen 2.897 N/A TYR 259.A N VAL 256.A O no hydrogen 3.439 N/A ALA 268.A N SER 264.A O no hydrogen 3.053 N/A VAL 269.A N GLU 265.A O no hydrogen 2.906 N/A LEU 270.A N GLU 266.A O no hydrogen 2.945 N/A LYS 271.A N VAL 267.A O no hydrogen 2.810 N/A LYS 271.A NZ TYR 56.A OH no hydrogen 3.221 N/A GLN 272.A N ALA 268.A O no hydrogen 2.996 N/A GLN 272.A NE2 VAL 269.A O no hydrogen 3.189 N/A LYS 273.A N VAL 269.A O no hydrogen 2.922 N/A LYS 273.A NZ PHE 44.A O no hydrogen 2.932 N/A LEU 274.A N LEU 270.A O no hydrogen 2.799 N/A GLU 275.A N LYS 271.A O no hydrogen 2.940 N/A ARG 276.A N GLN 272.A O no hydrogen 2.953 N/A CYS 277.A N LYS 273.A O no hydrogen 2.897 N/A HIS 278.A N LEU 274.A O no hydrogen 2.875 N/A SER 279.A N GLU 275.A O no hydrogen 2.906 N/A SER 279.A OG GLU 275.A O no hydrogen 3.043 N/A ALA 280.A N ARG 276.A O no hydrogen 3.095 N/A