Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6xdh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N GLU 5.A OE1 no hydrogen 2.506 N/A ASN 6.A N SER 3.A OG no hydrogen 2.955 N/A ASN 6.A ND2 GLN 20.A O no hydrogen 2.847 N/A ASN 6.A ND2 GLY 22.A O no hydrogen 3.010 N/A VAL 7.A N SER 3.A O no hydrogen 2.924 N/A ALA 8.A N LEU 4.A O no hydrogen 2.972 N/A PHE 9.A N GLU 5.A O no hydrogen 2.847 N/A ASN 10.A N ASN 6.A O no hydrogen 3.027 N/A ASN 10.A ND2 ASN 6.A O no hydrogen 2.904 N/A ASN 10.A ND2 GLN 20.A O no hydrogen 3.018 N/A VAL 11.A N VAL 7.A O no hydrogen 2.996 N/A VAL 12.A N ALA 8.A O no hydrogen 2.927 N/A ASN 13.A N PHE 9.A O no hydrogen 2.970 N/A ASN 13.A ND2 PHE 9.A O no hydrogen 3.053 N/A LYS 14.A N ASN 10.A O no hydrogen 2.641 N/A GLY 15.A N VAL 11.A O no hydrogen 3.005 N/A PHE 17.A N ALA 61.A O no hydrogen 2.784 N/A ASP 18.A N ASN 10.A OD1 no hydrogen 3.001 N/A GLN 20.A N ASN 10.A OD1 no hydrogen 2.983 N/A GLN 20.A NE2 ASP 18.A O no hydrogen 3.638 N/A GLN 20.A NE2 ASP 18.A OD2 no hydrogen 3.191 N/A VAL 24.A N GLU 5.A O no hydrogen 3.403 N/A SER 27.A N TYR 34.A O no hydrogen 2.902 N/A ILE 29.A N THR 32.A O no hydrogen 3.130 N/A THR 32.A N ILE 29.A O no hydrogen 2.870 N/A THR 32.A OG1 ASN 30.A O no hydrogen 2.974 N/A VAL 33.A N PHE 45.A O no hydrogen 2.825 N/A TYR 34.A N SER 27.A O no hydrogen 2.794 N/A THR 35.A N VAL 42.A O no hydrogen 2.957 N/A THR 35.A OG1 PRO 25.A O no hydrogen 2.592 N/A LYS 36.A NZ ASP 41.A OD1 no hydrogen 2.361 N/A VAL 37.A N VAL 40.A O no hydrogen 3.013 N/A VAL 40.A N VAL 37.A O no hydrogen 3.302 N/A VAL 42.A N THR 35.A O no hydrogen 2.863 N/A LEU 44.A N VAL 33.A O no hydrogen 2.749 N/A PHE 45.A N VAL 33.A O no hydrogen 3.342 N/A ASN 47.A N ASN 31.A O no hydrogen 2.864 N/A ASN 47.A ND2 ASN 31.A OD1 no hydrogen 2.940 N/A ASN 47.A ND2 LEU 51.A O no hydrogen 2.803 N/A THR 49.A N ASN 47.A OD1 no hydrogen 2.901 N/A THR 49.A OG1 ASN 47.A OD1 no hydrogen 2.734 N/A THR 49.A OG1 LEU 51.A O no hydrogen 3.529 N/A LEU 51.A N THR 49.A OG1 no hydrogen 2.958 N/A ALA 56.A N PRO 52.A O no hydrogen 2.871 N/A PHE 57.A N VAL 53.A O no hydrogen 2.945 N/A GLU 58.A N ASN 54.A O no hydrogen 3.160 N/A LEU 59.A N VAL 55.A O no hydrogen 3.028 N/A TRP 60.A N ALA 56.A O no hydrogen 2.879 N/A ALA 61.A N PHE 57.A O no hydrogen 2.928 N/A LYS 62.A N GLU 58.A O no hydrogen 2.886 N/A LYS 62.A NZ GLU 58.A OE2 no hydrogen 2.677 N/A LYS 62.A NZ VAL 103.A O no hydrogen 2.746 N/A ARG 63.A N TRP 60.A O no hydrogen 3.088 N/A ARG 63.A NH1 TRP 60.A O no hydrogen 2.801 N/A ARG 63.A NH2 GLY 15.A O no hydrogen 3.527 N/A ASN 64.A N VAL 86.A O no hydrogen 2.846 N/A ASN 64.A ND2 THR 85.A OG1 no hydrogen 3.216 N/A LYS 66.A N ASN 64.A OD1 no hydrogen 2.778 N/A LYS 66.A NZ ASP 126.A OD2 no hydrogen 3.036 N/A VAL 68.A N SER 163.A O no hydrogen 2.805 N/A LYS 72.A N ASP 274.A OD2 no hydrogen 2.983 N/A LYS 72.A NZ THR 197.A OG1 no hydrogen 2.791 N/A LYS 72.A NZ SER 199.A OG no hydrogen 2.947 N/A ILE 73.A N GLU 70.A O no hydrogen 2.895 N/A LEU 74.A N GLU 70.A O no hydrogen 3.367 N/A ASN 75.A N VAL 71.A O no hydrogen 2.846 N/A ASN 76.A N LYS 72.A O no hydrogen 2.950 N/A ASN 76.A ND2 THR 276.A OG1 no hydrogen 2.850 N/A ASN 76.A ND2 ASP 325.A O no hydrogen 2.929 N/A LEU 77.A N ILE 73.A O no hydrogen 2.989 N/A GLY 78.A N ASN 75.A O no hydrogen 2.940 N/A VAL 79.A N LEU 74.A O no hydrogen 3.013 N/A ASP 80.A N THR 122.A O no hydrogen 2.887 N/A ALA 83.A N PHE 124.A O no hydrogen 3.053 N/A ASN 84.A ND2 LYS 111.A O no hydrogen 3.459 N/A ASP 89.A N ALA 94.A O no hydrogen 2.777 N/A LYS 91.A N ASP 89.A OD1 no hydrogen 3.001 N/A ARG 92.A N ASP 89.A O no hydrogen 3.260 N/A ARG 92.A N ASP 89.A OD1 no hydrogen 3.202 N/A ARG 92.A NH2 ASP 89.A OD2 no hydrogen 3.245 N/A ARG 92.A NH2 PRO 95.A O no hydrogen 3.098 N/A ALA 94.A N ASP 89.A O no hydrogen 3.198 N/A ALA 96.A N ILE 87.A O no hydrogen 2.830 N/A THR 100.A N THR 107.A O no hydrogen 3.052 N/A THR 100.A OG1 THR 107.A OG1 no hydrogen 2.729 N/A THR 100.A OG1 ASP 108.A OD1 no hydrogen 2.615 N/A GLY 102.A N ALA 110.A O no hydrogen 2.883 N/A VAL 103.A N ASP 108.A OD1 no hydrogen 2.916 N/A VAL 103.A N ASP 108.A OD2 no hydrogen 3.225 N/A CYS 104.A N ASP 108.A OD1 no hydrogen 3.044 N/A THR 107.A N CYS 104.A O no hydrogen 3.183 N/A THR 107.A OG1 THR 100.A OG1 no hydrogen 2.729 N/A ASP 108.A N CYS 104.A O no hydrogen 2.825 N/A ILE 109.A N THR 100.A O no hydrogen 2.897 N/A LYS 111.A N GLU 115.A OE2 no hydrogen 2.691 N/A LYS 111.A NZ ASP 108.A OD2 no hydrogen 2.799 N/A LYS 112.A N GLU 115.A OE2 no hydrogen 2.919 N/A GLU 115.A N LYS 112.A O no hydrogen 3.205 N/A CYS 118.A N GLU 115.A O no hydrogen 2.925 N/A CYS 118.A SG LYS 112.A O no hydrogen 4.016 N/A ALA 119.A N THR 116.A O no hydrogen 3.163 N/A LEU 121.A N CYS 118.A O no hydrogen 3.029 N/A THR 122.A N ASP 80.A OD2 no hydrogen 2.924 N/A VAL 123.A N ASN 141.A O no hydrogen 3.248 N/A PHE 124.A N ILE 81.A O no hydrogen 2.817 N/A PHE 125.A N VAL 143.A O no hydrogen 2.725 N/A ASP 126.A N GLN 132.A OE1 no hydrogen 2.964 N/A GLY 127.A N ILE 145.A O no hydrogen 2.684 N/A ARG 128.A N ASP 126.A OD1 no hydrogen 3.033 N/A ARG 128.A NE ASP 126.A OD1 no hydrogen 2.807 N/A ARG 128.A NE ASP 126.A OD2 no hydrogen 3.284 N/A ARG 128.A NH1 PRO 67.A O no hydrogen 2.829 N/A ARG 128.A NH2 PRO 67.A O no hydrogen 2.890 N/A ARG 128.A NH2 ASP 126.A OD2 no hydrogen 2.700 N/A VAL 129.A N ASP 126.A O no hydrogen 2.882 N/A GLN 132.A N VAL 129.A O no hydrogen 3.205 N/A GLN 132.A NE2 ALA 83.A O no hydrogen 3.302 N/A LEU 135.A N GLY 131.A O no hydrogen 3.101 N/A PHE 136.A N GLN 132.A O no hydrogen 2.930 N/A ARG 137.A N VAL 133.A O no hydrogen 3.007 N/A ARG 137.A NH2 LYS 151.A O no hydrogen 2.684 N/A ASN 138.A N ASP 134.A O no hydrogen 3.176 N/A ASN 138.A N LEU 135.A O no hydrogen 3.267 N/A ALA 139.A N PHE 136.A O no hydrogen 3.000 N/A ASN 141.A ND2 ALA 119.A O no hydrogen 2.791 N/A GLY 142.A N LYS 183.A O no hydrogen 3.031 N/A VAL 143.A N VAL 123.A O no hydrogen 2.844 N/A LEU 144.A N TYR 181.A O no hydrogen 2.823 N/A ILE 145.A N PHE 125.A O no hydrogen 3.064 N/A THR 146.A N ASN 179.A O no hydrogen 3.179 N/A THR 146.A OG1 GLY 148.A O no hydrogen 2.741 N/A LEU 153.A N VAL 150.A O no hydrogen 3.026 N/A GLN 154.A NE2 GLY 152.A O no hydrogen 2.911 N/A SER 156.A N TYR 180.A O no hydrogen 3.106 N/A SER 156.A OG TYR 326.A OH no hydrogen 2.832 N/A GLY 158.A N PHE 178.A O no hydrogen 2.937 N/A GLN 161.A N GLN 161.A OE1 no hydrogen 2.763 N/A GLN 161.A NE2 THR 197.A O no hydrogen 2.842 N/A GLN 161.A NE2 SER 199.A OG no hydrogen 2.995 N/A ALA 162.A N LEU 169.A O no hydrogen 3.029 N/A SER 163.A N VAL 68.A O no hydrogen 2.848 N/A LEU 164.A N VAL 167.A O no hydrogen 2.692 N/A VAL 167.A N LEU 164.A O no hydrogen 2.959 N/A THR 168.A OG1 GLU 70.A OE2 no hydrogen 2.999 N/A LEU 169.A N ALA 162.A O no hydrogen 2.914 N/A GLY 171.A N THR 176.A OG1 no hydrogen 3.083 N/A LYS 175.A NZ GLU 147.A O no hydrogen 3.477 N/A THR 176.A OG1 LYS 160.A O no hydrogen 2.702 N/A GLN 177.A NE2.B GLY 158.A O no hydrogen 3.483 N/A ASN 179.A N THR 146.A O no hydrogen 2.869 N/A ASN 179.A ND2 GLY 148.A O no hydrogen 2.998 N/A TYR 180.A N SER 156.A O no hydrogen 2.700 N/A TYR 181.A N LEU 144.A O no hydrogen 2.892 N/A LYS 182.A NZ LEU 77.A O no hydrogen 2.870 N/A LYS 183.A N GLY 142.A O no hydrogen 2.803 N/A LYS 183.A NZ PHE 136.A O no hydrogen 3.053 N/A LYS 183.A NZ ALA 139.A O no hydrogen 2.764 N/A VAL 184.A N VAL 187.A O no hydrogen 2.885 N/A ASP 185.A N ASN 141.A OD1 no hydrogen 2.882 N/A GLY 186.A N ARG 140.A O no hydrogen 2.703 N/A VAL 187.A N VAL 184.A O no hydrogen 2.916 N/A GLN 189.A N LYS 182.A O no hydrogen 2.860 N/A THR 194.A OG1 TYR 195.A O no hydrogen 2.842 N/A TYR 195.A N THR 323.A O no hydrogen 2.971 N/A TYR 195.A OH GLU 306.A OE1 no hydrogen 2.827 N/A THR 197.A N ASP 325.A OD1 no hydrogen 2.840 N/A THR 197.A OG1 ASP 325.A OD1 no hydrogen 3.231 N/A THR 197.A OG1 ASP 325.A OD2 no hydrogen 2.597 N/A GLN 198.A N ASP 298.A O no hydrogen 2.805 N/A GLN 198.A NE2 PHE 196.A O no hydrogen 3.475 N/A SER 199.A OG GLU 70.A OE1 no hydrogen 2.489 N/A SER 199.A OG GLU 70.A OE2 no hydrogen 3.478 N/A ARG 200.A N ASP 298.A OD2 no hydrogen 2.880 N/A ARG 200.A NE ASP 298.A OD1 no hydrogen 3.330 N/A ARG 200.A NE ASP 298.A OD2 no hydrogen 3.159 N/A ARG 200.A NH1 LYS 206.A O no hydrogen 3.208 N/A ARG 200.A NH1 GLU 212.A OE2 no hydrogen 2.686 N/A ARG 200.A NH2 GLU 212.A OE1 no hydrogen 3.020 N/A ARG 200.A NH2 ASP 298.A OD1 no hydrogen 2.992 N/A GLU 204.A N ASN 201.A OD1 no hydrogen 2.700 N/A ARG 208.A N GLU 212.A OE2 no hydrogen 2.897 N/A ARG 208.A NH1 GLN 198.A O no hydrogen 3.117 N/A ARG 208.A NH1 GLN 198.A OE1 no hydrogen 2.899 N/A SER 209.A OG ASP 302.A OD1 no hydrogen 2.400 N/A GLN 210.A NE2 ASP 214.A OD1 no hydrogen 3.267 N/A GLU 212.A N SER 209.A OG no hydrogen 3.227 N/A ILE 213.A N SER 209.A O no hydrogen 2.995 N/A ASP 214.A N GLN 210.A O no hydrogen 2.829 N/A PHE 215.A N MET 211.A O no hydrogen 2.859 N/A LEU 216.A N GLU 212.A O no hydrogen 3.153 N/A GLU 217.A N ILE 213.A O no hydrogen 3.110 N/A LEU 218.A N ASP 214.A O no hydrogen 2.817 N/A PHE 223.A N ALA 219.A O no hydrogen 2.980 N/A ILE 224.A N MET 220.A O no hydrogen 2.972 N/A GLU 225.A N ASP 221.A O no hydrogen 3.153 N/A ARG 226.A N GLU 222.A O no hydrogen 2.866 N/A TYR 227.A N PHE 223.A O no hydrogen 3.092 N/A TYR 227.A OH ASP 214.A OD2 no hydrogen 2.311 N/A LYS 228.A N GLU 225.A O no hydrogen 3.416 N/A LEU 229.A N ILE 224.A O no hydrogen 2.984 N/A GLU 230.A N GLU 230.A OE1 no hydrogen 2.693 N/A TYR 232.A N LEU 229.A O no hydrogen 3.195 N/A GLU 235.A N GLU 235.A OE2 no hydrogen 2.717 N/A HIS 236.A N ALA 233.A O no hydrogen 3.142 N/A ILE 237.A N ALA 233.A O no hydrogen 2.785 N/A VAL 238.A N PHE 234.A O no hydrogen 3.005 N/A TYR 239.A N PHE 234.A O no hydrogen 3.010 N/A ASP 241.A N GLY 248.A O no hydrogen 2.847 N/A SER 243.A N ASP 241.A OD1 no hydrogen 2.972 N/A SER 243.A OG ASP 241.A OD1 no hydrogen 2.731 N/A LEU 247.A N SER 290.A O no hydrogen 2.744 N/A GLY 248.A N ASP 241.A O no hydrogen 2.864 N/A LEU 250.A N HIS 236.A O no hydrogen 3.182 N/A HIS 251.A N ILE 237.A O no hydrogen 2.881 N/A HIS 251.A ND1 SER 295.A O no hydrogen 2.672 N/A LEU 253.A N ILE 297.A O no hydrogen 3.058 N/A GLY 255.A N LEU 252.A O no hydrogen 2.823 N/A LEU 256.A N LEU 252.A O no hydrogen 3.405 N/A ALA 257.A N LEU 253.A O no hydrogen 2.929 N/A LYS 258.A N ILE 254.A O no hydrogen 3.128 N/A LYS 258.A NZ PHE 215.A O no hydrogen 3.241 N/A LYS 258.A NZ LEU 216.A O no hydrogen 2.827 N/A LYS 258.A NZ LEU 218.A O no hydrogen 3.189 N/A ARG 259.A N GLY 255.A O no hydrogen 3.116 N/A ARG 259.A NE ASP 284.A OD1 no hydrogen 3.109 N/A ARG 259.A NH2 ASP 284.A OD1 no hydrogen 3.103 N/A ARG 259.A NH2 ASP 284.A OD2 no hydrogen 2.880 N/A PHE 260.A N LEU 256.A O no hydrogen 2.799 N/A LYS 261.A N ALA 257.A O no hydrogen 3.128 N/A GLU 262.A N ARG 259.A O no hydrogen 3.130 N/A SER 263.A N ARG 259.A O no hydrogen 3.061 N/A GLU 266.A N THR 283.A O no hydrogen 2.968 N/A GLU 268.A N PHE 281.A O no hydrogen 2.912 N/A MET 273.A N ILE 271.A O no hydrogen 2.837 N/A SER 275.A OG VAL 277.A O no hydrogen 2.645 N/A THR 276.A OG1 ASP 325.A OD2 no hydrogen 2.697 N/A LYS 278.A N VAL 296.A O no hydrogen 2.905 N/A LYS 278.A NZ ASP 269.A OD1 no hydrogen 2.946 N/A LYS 278.A NZ ILE 271.A O no hydrogen 3.098 N/A LYS 278.A NZ MET 273.A O no hydrogen 2.763 N/A TYR 280.A N CYS 294.A O no hydrogen 2.980 N/A PHE 281.A N GLU 268.A O no hydrogen 3.025 N/A ILE 282.A N LYS 291.A O no hydrogen 3.006 N/A THR 283.A N GLU 266.A O no hydrogen 3.011 N/A ASP 284.A N SER 289.A O no hydrogen 2.857 N/A THR 287.A N ASP 284.A OD2 no hydrogen 2.854 N/A THR 287.A OG1 PHE 242.A O no hydrogen 3.544 N/A THR 287.A OG1 ASP 284.A OD2 no hydrogen 2.912 N/A GLY 288.A N ASP 284.A O no hydrogen 2.867 N/A SER 289.A N THR 287.A OG1 no hydrogen 3.016 N/A SER 289.A OG HIS 244.A O no hydrogen 2.707 N/A SER 290.A N SER 245.A O no hydrogen 3.003 N/A LYS 291.A N ILE 282.A O no hydrogen 3.027 N/A LYS 291.A NZ LEU 247.A O no hydrogen 2.975 N/A LYS 291.A NZ GLY 249.A O no hydrogen 3.045 N/A CYS 294.A N TYR 280.A O no hydrogen 2.768 N/A CYS 294.A SG GLY 249.A O no hydrogen 3.696 N/A CYS 294.A SG LEU 250.A O no hydrogen 3.333 N/A SER 295.A OG HIS 251.A ND1 no hydrogen 3.341 N/A SER 295.A OG PRO 345.A O no hydrogen 3.363 N/A VAL 296.A N LYS 278.A O no hydrogen 2.709 N/A ILE 297.A N HIS 251.A O no hydrogen 3.022 N/A LEU 301.A N GLU 212.A OE1 no hydrogen 2.841 N/A PHE 304.A N LEU 300.A O no hydrogen 3.060 N/A VAL 305.A N LEU 301.A O no hydrogen 2.894 N/A GLU 306.A N ASP 302.A O no hydrogen 2.878 N/A ILE 307.A N ASP 303.A O no hydrogen 2.846 N/A ILE 308.A N PHE 304.A O no hydrogen 2.949 N/A LYS 309.A N VAL 305.A O no hydrogen 2.955 N/A LYS 309.A NZ TYR 227.A O no hydrogen 3.143 N/A LYS 309.A NZ LYS 228.A O no hydrogen 3.547 N/A SER 310.A N ILE 307.A O no hydrogen 3.164 N/A SER 310.A OG GLU 306.A O no hydrogen 3.174 N/A SER 310.A OG ILE 307.A O no hydrogen 2.656 N/A GLN 311.A N ILE 308.A O no hydrogen 3.377 N/A GLN 311.A NE2 ILE 307.A O no hydrogen 3.006 N/A SER 314.A N ASP 312.A OD1 no hydrogen 2.896 N/A SER 314.A OG ASP 312.A OD1 no hydrogen 2.344 N/A LYS 318.A N LEU 333.A O no hydrogen 3.044 N/A VAL 320.A N PHE 331.A O no hydrogen 2.825 N/A VAL 322.A N ILE 329.A O no hydrogen 2.832 N/A ILE 324.A N THR 327.A O no hydrogen 2.755 N/A ASP 325.A N TYR 195.A O no hydrogen 2.731 N/A TYR 326.A N THR 194.A OG1 no hydrogen 3.076 N/A TYR 326.A OH SER 156.A OG no hydrogen 2.832 N/A THR 327.A N ILE 324.A O no hydrogen 2.919 N/A ILE 329.A N VAL 322.A O no hydrogen 2.675 N/A PHE 331.A N VAL 320.A O no hydrogen 2.628 N/A MET 332.A N TYR 344.A O no hydrogen 2.751 N/A LEU 333.A N LYS 318.A O no hydrogen 2.899 N/A TRP 334.A N THR 342.A O no hydrogen 2.818 N/A CYS 335.A N VAL 316.A O no hydrogen 3.096 N/A LYS 336.A N HIS 339.A O no hydrogen 2.962 N/A HIS 339.A N LYS 336.A O no hydrogen 3.119 N/A VAL 340.A N GLY 231.A O no hydrogen 2.806 N/A GLU 341.A N TRP 334.A O no hydrogen 2.531 N/A THR 342.A N TRP 334.A O no hydrogen 3.125 N/A TYR 344.A N MET 332.A O no hydrogen 3.079 N/A LYS 346.A N SER 330.A O no hydrogen 2.734 N/A