Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6xkm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N SER 1.A O no hydrogen 2.964 N/A TRP 5.A N SER 2.A O no hydrogen 3.332 N/A GLN 6.A N GLN 3.A O no hydrogen 3.159 N/A VAL 9.A N VAL 194.A O no hydrogen 2.848 N/A MET 11.A N ALA 192.A O no hydrogen 2.962 N/A TYR 15.A N PRO 12.A O no hydrogen 3.150 N/A LYS 16.A N ASN 13.A O no hydrogen 3.030 N/A LYS 16.A NZ ASN 13.A OD1 no hydrogen 3.033 N/A LYS 16.A NZ TRP 190.A O no hydrogen 2.783 N/A MET 17.A N LEU 14.A O no hydrogen 3.377 N/A GLN 18.A NE2 LEU 14.A O no hydrogen 2.926 N/A MET 20.A N ASN 227.A OD1 no hydrogen 3.202 N/A LYS 24.A NZ CYS 25.A O no hydrogen 3.341 N/A CYS 25.A N GLU 173.A OE2 no hydrogen 2.803 N/A CYS 25.A SG ASN 233.A OD1 no hydrogen 3.716 N/A ASP 26.A N ASN 233.A OD1 no hydrogen 2.793 N/A ASP 32.A N ASN 29.A O no hydrogen 3.042 N/A ILE 40.A N PRO 37.A O no hydrogen 3.204 N/A VAL 44.A N MET 41.A O no hydrogen 3.083 N/A ALA 45.A N MET 41.A O no hydrogen 3.194 N/A LYS 46.A N MET 42.A O no hydrogen 2.802 N/A LYS 46.A NZ ASN 43.A OD1 no hydrogen 3.454 N/A LYS 46.A NZ GLU 203.A OE1 no hydrogen 3.024 N/A LYS 46.A NZ GLU 203.A OE2 no hydrogen 3.310 N/A TYR 47.A N ASN 43.A O no hydrogen 3.035 N/A TYR 47.A OH HIS 69.A NE2 no hydrogen 2.621 N/A THR 48.A N VAL 44.A O no hydrogen 2.954 N/A THR 48.A OG1 VAL 44.A O no hydrogen 2.710 N/A GLN 49.A N ALA 45.A O no hydrogen 3.044 N/A GLN 49.A NE2 SER 240.A O no hydrogen 3.451 N/A GLN 49.A NE2 SER 243.A OG no hydrogen 3.069 N/A LEU 50.A N LYS 46.A O no hydrogen 3.017 N/A CYS 51.A N TYR 47.A O no hydrogen 2.929 N/A CYS 51.A SG TYR 47.A O no hydrogen 3.244 N/A GLN 52.A N THR 48.A O no hydrogen 2.816 N/A GLN 52.A NE2 SER 243.A O no hydrogen 2.699 N/A TYR 53.A N GLN 49.A O no hydrogen 2.935 N/A LEU 54.A N LEU 50.A O no hydrogen 2.843 N/A ASN 55.A N CYS 51.A O no hydrogen 3.056 N/A ASN 55.A ND2 PHE 250.A O no hydrogen 2.700 N/A THR 56.A N TYR 53.A O no hydrogen 2.926 N/A THR 56.A OG1 TYR 53.A O no hydrogen 2.500 N/A LEU 57.A N LEU 54.A O no hydrogen 3.056 N/A THR 58.A OG1 ASN 210.A OD1 no hydrogen 2.766 N/A VAL 61.A N THR 257.A OG1 no hydrogen 3.040 N/A ARG 66.A N ASP 125.A OD2 no hydrogen 2.801 N/A ARG 66.A NH1 LYS 123.A O no hydrogen 3.036 N/A ARG 66.A NH1 GLU 284.A OE1 no hydrogen 2.932 N/A ARG 66.A NH2 GLU 284.A OE1 no hydrogen 3.514 N/A VAL 67.A N LEU 94.A O no hydrogen 2.834 N/A ILE 68.A N LEU 126.A O no hydrogen 3.052 N/A HIS 69.A N VAL 96.A O no hydrogen 2.819 N/A HIS 69.A ND1 THR 82.A OG1 no hydrogen 2.935 N/A HIS 69.A NE2 TYR 47.A OH no hydrogen 2.621 N/A PHE 70.A N ILE 128.A O no hydrogen 2.765 N/A ALA 72.A N SER 98.A O no hydrogen 2.961 N/A GLY 73.A N ASP 99.A OD2 no hydrogen 2.933 N/A SER 74.A OG VAL 78.A O no hydrogen 3.045 N/A GLY 77.A N SER 74.A O no hydrogen 3.253 N/A THR 82.A OG1 HIS 69.A ND1 no hydrogen 2.935 N/A THR 82.A OG1 ASP 97.A OD2 no hydrogen 2.757 N/A ALA 83.A N ALA 79.A O no hydrogen 3.166 N/A VAL 84.A N PRO 80.A O no hydrogen 3.237 N/A LEU 85.A N GLY 81.A O no hydrogen 2.966 N/A ARG 86.A N THR 82.A O no hydrogen 2.834 N/A ARG 86.A NH1 THR 93.A O no hydrogen 2.911 N/A ARG 86.A NH1 ASP 108.A OD2 no hydrogen 3.421 N/A ARG 86.A NH2 ASP 108.A OD1 no hydrogen 3.290 N/A ARG 86.A NH2 ASP 108.A OD2 no hydrogen 3.230 N/A GLN 87.A N ALA 83.A O no hydrogen 3.131 N/A TRP 88.A N VAL 84.A O no hydrogen 2.824 N/A TRP 88.A NE1 ASN 55.A OD1 no hydrogen 2.878 N/A LEU 89.A N LEU 85.A O no hydrogen 2.767 N/A THR 93.A N PRO 90.A O no hydrogen 3.148 N/A THR 93.A OG1 PRO 90.A O no hydrogen 2.590 N/A LEU 94.A N MET 65.A O no hydrogen 2.797 N/A LEU 95.A N ASP 108.A OD2 no hydrogen 2.767 N/A VAL 96.A N VAL 67.A O no hydrogen 3.043 N/A ASP 97.A N SER 109.A O no hydrogen 2.995 N/A SER 98.A N HIS 69.A O no hydrogen 2.926 N/A SER 98.A OG LEU 111.A O no hydrogen 2.697 N/A ASP 99.A N LEU 111.A O no hydrogen 3.334 N/A ASN 101.A N ASP 99.A OD1 no hydrogen 2.835 N/A VAL 104.A N GLY 77.A O no hydrogen 2.958 N/A SER 105.A OG ASP 97.A OD2 no hydrogen 2.393 N/A ALA 107.A N SER 105.A OG no hydrogen 2.906 N/A ASP 108.A N LEU 95.A O no hydrogen 2.816 N/A THR 110.A OG1 ASP 97.A OD1 no hydrogen 2.521 N/A LEU 111.A N ASP 97.A O no hydrogen 3.000 N/A GLY 113.A N ASP 99.A O no hydrogen 2.951 N/A CYS 115.A SG ASP 114.A OD1 no hydrogen 3.806 N/A ALA 116.A N ASP 114.A OD1 no hydrogen 3.016 N/A THR 117.A N ASP 114.A O no hydrogen 2.947 N/A THR 117.A OG1 ASP 114.A O no hydrogen 2.824 N/A THR 117.A OG1 SER 292.A OG no hydrogen 3.409 N/A VAL 118.A N CYS 115.A O no hydrogen 3.170 N/A HIS 119.A N SER 291.A O no hydrogen 2.930 N/A HIS 119.A NE2 ASP 293.A OD2 no hydrogen 2.599 N/A THR 120.A OG1 ASN 122.A O no hydrogen 3.398 N/A THR 120.A OG1 VAL 289.A O no hydrogen 3.276 N/A ALA 121.A N VAL 289.A O no hydrogen 3.287 N/A ASN 122.A ND2 LYS 123.A O no hydrogen 3.531 N/A LYS 123.A NZ GLN 159.A O no hydrogen 3.335 N/A TRP 124.A N LYS 160.A O no hydrogen 2.774 N/A ASP 125.A N ARG 66.A O no hydrogen 2.895 N/A LEU 126.A N ARG 66.A O no hydrogen 3.258 N/A ILE 127.A N SER 166.A O no hydrogen 3.149 N/A ILE 128.A N ILE 68.A O no hydrogen 3.005 N/A SER 129.A N ALA 168.A O no hydrogen 2.796 N/A ASP 130.A N PHE 70.A O no hydrogen 2.887 N/A MET 131.A N SER 129.A OG no hydrogen 3.358 N/A THR 136.A N ASP 133.A O no hydrogen 3.217 N/A THR 136.A OG1 ASP 133.A O no hydrogen 2.934 N/A LYS 137.A N PRO 134.A O no hydrogen 3.295 N/A THR 140.A N ASN 138.A OD1 no hydrogen 3.406 N/A THR 140.A OG1 ASN 138.A OD1 no hydrogen 2.818 N/A ASN 143.A ND2 GLU 173.A O no hydrogen 2.839 N/A SER 145.A N ASP 144.A OD1 no hydrogen 2.931 N/A LYS 146.A N TRP 176.A O no hydrogen 2.811 N/A LYS 146.A NZ ASP 144.A O no hydrogen 2.856 N/A LYS 146.A NZ HIS 174.A O no hydrogen 2.865 N/A PHE 150.A N GLU 147.A O no hydrogen 3.029 N/A THR 151.A N GLY 148.A O no hydrogen 3.130 N/A TYR 152.A OH VAL 118.A O no hydrogen 2.788 N/A ILE 153.A N PHE 149.A O no hydrogen 2.952 N/A CYS 154.A N PHE 150.A O no hydrogen 3.010 N/A CYS 154.A SG PHE 150.A O no hydrogen 3.357 N/A CYS 154.A SG ASN 177.A OD1 no hydrogen 3.857 N/A GLY 155.A N THR 151.A O no hydrogen 3.316 N/A PHE 156.A N TYR 152.A O no hydrogen 2.827 N/A ILE 157.A N ILE 153.A O no hydrogen 2.979 N/A GLN 158.A N CYS 154.A O no hydrogen 3.265 N/A GLN 159.A N GLY 155.A O no hydrogen 3.121 N/A GLN 159.A N PHE 156.A O no hydrogen 3.352 N/A LYS 160.A N PHE 156.A O no hydrogen 2.677 N/A LYS 160.A NZ THR 120.A O no hydrogen 2.994 N/A LEU 161.A N ILE 157.A O no hydrogen 3.157 N/A ALA 162.A N TRP 124.A O no hydrogen 2.767 N/A LEU 163.A N ILE 282.A O no hydrogen 3.313 N/A GLY 164.A N TYR 211.A O no hydrogen 2.791 N/A GLY 165.A N ALA 162.A O no hydrogen 2.865 N/A SER 166.A N ASP 125.A O no hydrogen 3.122 N/A VAL 167.A N GLY 208.A O no hydrogen 2.872 N/A ALA 168.A N ILE 127.A O no hydrogen 2.851 N/A ILE 169.A N LEU 206.A O no hydrogen 2.934 N/A LYS 170.A N SER 129.A O no hydrogen 2.898 N/A LYS 170.A NZ ASP 130.A OD1 no hydrogen 2.810 N/A LYS 170.A NZ GLU 203.A OE1 no hydrogen 2.888 N/A ILE 171.A N ALA 204.A O no hydrogen 2.851 N/A THR 172.A N SER 175.A O no hydrogen 2.884 N/A GLU 173.A N SER 202.A OG no hydrogen 2.935 N/A SER 175.A N THR 172.A OG1 no hydrogen 2.774 N/A TRP 176.A NE1 ASN 143.A OD1 no hydrogen 3.046 N/A ASN 177.A ND2 LYS 146.A O no hydrogen 2.741 N/A ALA 178.A N SER 145.A OG no hydrogen 2.781 N/A LEU 180.A N ASN 177.A OD1 no hydrogen 2.921 N/A TYR 181.A OH HIS 225.A ND1 no hydrogen 2.784 N/A LYS 182.A N ALA 178.A O no hydrogen 3.142 N/A LEU 183.A N ASP 179.A O no hydrogen 3.095 N/A MET 184.A N TYR 181.A O no hydrogen 3.114 N/A GLY 185.A N LYS 182.A O no hydrogen 3.286 N/A HIS 186.A N LEU 183.A O no hydrogen 2.844 N/A PHE 187.A N MET 184.A O no hydrogen 3.284 N/A ALA 188.A N ASN 210.A O no hydrogen 2.994 N/A TRP 189.A N CYS 209.A O no hydrogen 3.356 N/A THR 191.A N ILE 207.A O no hydrogen 3.028 N/A THR 191.A OG1 ALA 192.A O no hydrogen 3.508 N/A PHE 193.A N PHE 205.A O no hydrogen 2.846 N/A VAL 194.A N VAL 9.A O no hydrogen 2.931 N/A ASN 196.A N PRO 7.A O no hydrogen 3.130 N/A ASN 196.A ND2 GLN 3.A O no hydrogen 2.768 N/A ASN 196.A ND2 GLN 6.A O no hydrogen 2.693 N/A VAL 197.A N GLN 49.A OE1 no hydrogen 2.997 N/A ASN 198.A N THR 195.A O no hydrogen 3.365 N/A ASN 198.A ND2 GLU 203.A OE2 no hydrogen 2.809 N/A SER 200.A OG ASP 32.A O no hydrogen 3.251 N/A SER 201.A N ASN 198.A O no hydrogen 2.884 N/A GLU 203.A N SER 201.A OG no hydrogen 3.047 N/A ALA 204.A N ILE 171.A O no hydrogen 2.947 N/A PHE 205.A N PHE 193.A O no hydrogen 2.827 N/A LEU 206.A N ILE 169.A O no hydrogen 2.774 N/A ILE 207.A N THR 191.A O no hydrogen 2.831 N/A GLY 208.A N VAL 167.A O no hydrogen 3.106 N/A CYS 209.A N TRP 189.A O no hydrogen 2.801 N/A CYS 209.A SG THR 58.A OG1 no hydrogen 3.550 N/A CYS 209.A SG ASN 210.A OD1 no hydrogen 3.508 N/A ASN 210.A N SER 166.A OG no hydrogen 3.061 N/A ASN 210.A ND2 THR 58.A O no hydrogen 2.968 N/A ASN 210.A ND2 GLY 164.A O no hydrogen 3.035 N/A TYR 211.A N GLY 165.A O no hydrogen 2.741 N/A LEU 212.A N HIS 186.A O no hydrogen 2.881 N/A ARG 216.A N GLY 185.A O no hydrogen 2.750 N/A ARG 216.A NH2 PHE 187.A O no hydrogen 3.359 N/A ARG 216.A NH2 GLU 217.A OE1 no hydrogen 3.389 N/A GLU 217.A N GLY 185.A O no hydrogen 3.390 N/A TYR 222.A N ASP 220.A OD1 no hydrogen 3.050 N/A TYR 222.A OH ASP 144.A OD1 no hydrogen 3.173 N/A VAL 223.A N ASP 220.A OD1 no hydrogen 3.491 N/A MET 224.A N ASP 220.A O no hydrogen 2.933 N/A HIS 225.A N GLY 221.A O no hydrogen 3.056 N/A HIS 225.A ND1 TYR 181.A OH no hydrogen 2.784 N/A HIS 225.A NE2 GLU 173.A O no hydrogen 2.786 N/A ALA 226.A N TYR 222.A O no hydrogen 3.187 N/A ASN 227.A N VAL 223.A O no hydrogen 2.854 N/A ASN 227.A ND2 LYS 16.A O no hydrogen 3.396 N/A ASN 227.A ND2 GLN 18.A O no hydrogen 2.839 N/A TYR 228.A N MET 224.A O no hydrogen 2.839 N/A TYR 228.A OH SER 202.A O no hydrogen 2.677 N/A ILE 229.A N HIS 225.A O no hydrogen 2.944 N/A PHE 230.A N ALA 226.A O no hydrogen 2.940 N/A TRP 231.A N ASN 227.A O no hydrogen 2.916 N/A ARG 232.A N TYR 228.A O no hydrogen 2.981 N/A ARG 232.A NH1 SER 201.A O no hydrogen 3.038 N/A ARG 232.A NH1 TYR 228.A OH no hydrogen 2.937 N/A ARG 232.A NH2 SER 201.A O no hydrogen 3.176 N/A ASN 233.A N ILE 229.A O no hydrogen 2.786 N/A ASN 233.A ND2 LYS 24.A O no hydrogen 3.032 N/A THR 234.A N PHE 230.A O no hydrogen 3.001 N/A THR 234.A N TRP 231.A O no hydrogen 3.299 N/A THR 234.A OG1 PHE 230.A O no hydrogen 2.824 N/A THR 234.A OG1 TRP 231.A O no hydrogen 3.442 N/A THR 234.A OG1 ASN 235.A OD1 no hydrogen 3.294 N/A ASN 235.A N TRP 231.A O no hydrogen 2.843 N/A ILE 237.A N ASN 29.A OD1 no hydrogen 3.356 N/A SER 240.A N ASN 196.A O no hydrogen 3.108 N/A SER 240.A OG ALA 4.A O no hydrogen 2.485 N/A SER 241.A OG THR 35.A O no hydrogen 2.554 N/A TYR 242.A N SER 240.A OG no hydrogen 3.324 N/A SER 243.A OG GLN 52.A OE1 no hydrogen 2.771 N/A LEU 244.A N SER 241.A O no hydrogen 3.056 N/A PHE 245.A N TYR 242.A O no hydrogen 3.086 N/A SER 248.A N ASP 246.A OD1 no hydrogen 3.305 N/A SER 248.A OG ASP 246.A OD1 no hydrogen 2.598 N/A PHE 250.A N MET 247.A O no hydrogen 3.304 N/A LEU 252.A N TRP 88.A O no hydrogen 2.979 N/A THR 257.A N VAL 61.A O no hydrogen 3.212 N/A MET 260.A N ILE 281.A O no hydrogen 2.966 N/A LYS 263.A N GLN 266.A OE1 no hydrogen 3.166 N/A GLN 266.A N LYS 263.A O no hydrogen 3.420 N/A ILE 267.A N GLU 264.A O no hydrogen 3.509 N/A ILE 271.A N ASN 268.A OD1 no hydrogen 2.700 N/A LEU 272.A N ASN 268.A O no hydrogen 3.433 N/A SER 273.A N ASP 269.A O no hydrogen 3.059 N/A LEU 275.A N ILE 271.A O no hydrogen 3.024 N/A SER 276.A N LEU 272.A O no hydrogen 3.012 N/A SER 276.A OG LEU 272.A O no hydrogen 2.830 N/A LYS 277.A N SER 273.A O no hydrogen 3.329 N/A GLY 278.A N LEU 275.A O no hydrogen 3.056 N/A ARG 279.A N LEU 274.A O no hydrogen 2.891 N/A ILE 281.A N ALA 258.A O no hydrogen 2.938 N/A ILE 282.A N LEU 163.A O no hydrogen 3.027 N/A ARG 283.A N MET 260.A O no hydrogen 3.247 N/A ARG 283.A NE ASP 125.A OD1 no hydrogen 2.795 N/A ARG 283.A NH1 ASP 125.A OD1 no hydrogen 3.410 N/A ARG 283.A NH1 ASP 125.A OD2 no hydrogen 2.932 N/A ARG 283.A NH2 GLU 284.A O no hydrogen 3.233 N/A ARG 283.A NH2 ASN 285.A OD1 no hydrogen 3.358 N/A VAL 289.A N ASN 122.A OD1 no hydrogen 2.946 N/A SER 291.A N HIS 119.A O no hydrogen 2.928 N/A SER 292.A OG ILE 112.A O no hydrogen 3.525 N/A SER 292.A OG THR 117.A OG1 no hydrogen 3.409 N/A ASP 293.A N THR 117.A O no hydrogen 2.813 N/A