Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6xon_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 5.A N ASN 1.A O no hydrogen 3.290 N/A LEU 6.A N ILE 2.A O no hydrogen 3.112 N/A ARG 7.A N PHE 3.A O no hydrogen 2.974 N/A ARG 7.A NE GLU 4.A OE1 no hydrogen 2.899 N/A ARG 7.A NH1 ASP 222.A OD1 no hydrogen 3.464 N/A ARG 7.A NH2 GLU 4.A OE1 no hydrogen 3.226 N/A ILE 8.A N GLU 4.A O no hydrogen 3.170 N/A ASP 9.A N MET 5.A O no hydrogen 3.141 N/A GLU 10.A N LEU 6.A O no hydrogen 2.862 N/A GLY 11.A N LEU 6.A O no hydrogen 3.320 N/A ARG 13.A N GLY 25.A O no hydrogen 3.312 N/A ILE 16.A N GLY 51.A O no hydrogen 3.009 N/A TYR 17.A N THR 23.A O no hydrogen 2.881 N/A ASP 19.A N TYR 21.A O no hydrogen 3.257 N/A THR 20.A N ASP 19.A OD1 no hydrogen 2.757 N/A THR 23.A N TYR 17.A O no hydrogen 2.777 N/A THR 23.A OG1 ASP 19.A OD2 no hydrogen 2.743 N/A THR 23.A OG1 TYR 21.A O no hydrogen 3.259 N/A ILE 24.A N HIS 28.A O no hydrogen 3.153 N/A GLY 25.A N ARG 13.A O no hydrogen 2.787 N/A HIS 28.A N ILE 24.A O no hydrogen 2.900 N/A HIS 28.A ND1 ASP 65.A OD1 no hydrogen 2.969 N/A HIS 28.A ND1 ASP 65.A OD2 no hydrogen 3.213 N/A LEU 30.A N TYR 22.A O no hydrogen 2.965 N/A ALA 36.A N SER 33.A O no hydrogen 3.145 N/A ALA 37.A N SER 33.A O no hydrogen 3.258 N/A LYS 38.A N LEU 34.A O no hydrogen 2.968 N/A SER 39.A N ASN 35.A O no hydrogen 2.987 N/A GLU 40.A N ALA 36.A O no hydrogen 2.906 N/A LEU 41.A N ALA 37.A O no hydrogen 3.038 N/A ASP 42.A N LYS 38.A O no hydrogen 2.994 N/A LYS 43.A N SER 39.A O no hydrogen 3.067 N/A ALA 44.A N GLU 40.A O no hydrogen 2.975 N/A ILE 45.A N LEU 41.A O no hydrogen 2.862 N/A GLY 46.A N ASP 42.A O no hydrogen 2.809 N/A ARG 47.A N ASP 42.A O no hydrogen 3.354 N/A ARG 47.A NE GLU 57.A OE1 no hydrogen 2.832 N/A ARG 47.A NH2 VAL 52.A O no hydrogen 2.859 N/A ARG 47.A NH2 GLU 57.A OE2 no hydrogen 2.811 N/A ASN 48.A ND2 ASN 50.A OD1 no hydrogen 3.335 N/A THR 49.A N ASP 42.A OD1 no hydrogen 2.949 N/A THR 49.A OG1 ASP 42.A OD1 no hydrogen 2.832 N/A VAL 52.A N THR 49.A O no hydrogen 3.259 N/A ILE 53.A N LEU 14.A O no hydrogen 2.814 N/A THR 54.A N GLU 57.A OE2 no hydrogen 3.167 N/A LYS 55.A NZ GLU 4.A OE2 no hydrogen 3.330 N/A GLU 57.A N THR 54.A OG1 no hydrogen 3.307 N/A ALA 58.A N THR 54.A O no hydrogen 3.029 N/A GLU 59.A N LYS 55.A O no hydrogen 2.966 N/A LYS 60.A N ASP 56.A O no hydrogen 3.097 N/A LEU 61.A N GLU 57.A O no hydrogen 3.421 N/A PHE 62.A N ALA 58.A O no hydrogen 3.040 N/A ASN 63.A N GLU 59.A O no hydrogen 2.913 N/A GLN 64.A N LYS 60.A O no hydrogen 3.302 N/A ASP 65.A N LEU 61.A O no hydrogen 3.165 N/A VAL 66.A N PHE 62.A O no hydrogen 2.860 N/A ASP 67.A N ASN 63.A O no hydrogen 3.281 N/A ALA 68.A N GLN 64.A O no hydrogen 3.034 N/A ALA 69.A N ASP 65.A O no hydrogen 2.873 N/A VAL 70.A N VAL 66.A O no hydrogen 2.796 N/A ARG 71.A N ASP 67.A O no hydrogen 2.998 N/A GLY 72.A N ALA 68.A O no hydrogen 3.087 N/A ILE 73.A N ALA 69.A O no hydrogen 2.947 N/A LEU 74.A N VAL 70.A O no hydrogen 3.173 N/A ARG 75.A N ARG 71.A O no hydrogen 3.266 N/A ARG 75.A N GLY 72.A O no hydrogen 3.122 N/A ASN 76.A N ILE 73.A O no hydrogen 3.059 N/A LYS 78.A N ASN 76.A OD1 no hydrogen 3.109 N/A LYS 80.A N ASN 76.A O no hydrogen 2.938 N/A LYS 80.A NZ ASP 84.A OD2 no hydrogen 3.207 N/A TYR 83.A N LEU 79.A O no hydrogen 3.025 N/A ASP 84.A N LYS 80.A O no hydrogen 3.209 N/A SER 85.A N PRO 81.A O no hydrogen 3.350 N/A SER 85.A OG PRO 81.A O no hydrogen 3.447 N/A SER 85.A OG VAL 82.A O no hydrogen 2.734 N/A LEU 86.A N VAL 82.A O no hydrogen 3.132 N/A ARG 90.A NE PHE 148.A O no hydrogen 2.816 N/A ARG 90.A NH1 ASP 87.A OD1 no hydrogen 2.811 N/A ARG 90.A NH1 ASP 87.A OD2 no hydrogen 3.545 N/A ARG 91.A N ASP 87.A O no hydrogen 2.842 N/A ARG 91.A NE TYR 83.A O no hydrogen 2.782 N/A ARG 91.A NH2 TYR 83.A O no hydrogen 3.464 N/A ARG 91.A NH2 ASP 84.A O no hydrogen 2.923 N/A ALA 92.A N ALA 88.A O no hydrogen 3.261 N/A ALA 93.A N VAL 89.A O no hydrogen 3.303 N/A LEU 94.A N ARG 90.A O no hydrogen 3.011 N/A ILE 95.A N ARG 91.A O no hydrogen 2.864 N/A ASN 96.A N ALA 92.A O no hydrogen 2.990 N/A ASN 96.A ND2 ASP 9.A OD2 no hydrogen 2.930 N/A MET 97.A N ALA 93.A O no hydrogen 3.325 N/A MET 97.A N LEU 94.A O no hydrogen 3.171 N/A VAL 98.A N LEU 94.A O no hydrogen 3.188 N/A PHE 99.A N ILE 95.A O no hydrogen 2.848 N/A GLN 100.A N ASN 96.A O no hydrogen 3.197 N/A GLN 100.A N MET 97.A O no hydrogen 3.185 N/A GLN 100.A NE2 THR 137.A OG1 no hydrogen 3.243 N/A MET 101.A N MET 97.A O no hydrogen 2.982 N/A GLY 102.A N VAL 98.A O no hydrogen 2.812 N/A VAL 106.A N GLY 102.A O no hydrogen 3.256 N/A ALA 107.A N GLU 103.A O no hydrogen 2.933 N/A PHE 109.A N VAL 106.A O no hydrogen 3.070 N/A THR 110.A OG1 ALA 107.A O no hydrogen 3.047 N/A SER 112.A OG ASN 127.A OD1 no hydrogen 3.104 N/A LEU 113.A N PHE 109.A O no hydrogen 2.898 N/A ARG 114.A N THR 110.A O no hydrogen 3.074 N/A ARG 114.A NH2 ASN 111.A OD1 no hydrogen 2.827 N/A MET 115.A N ASN 111.A O no hydrogen 3.312 N/A LEU 116.A N SER 112.A O no hydrogen 3.091 N/A GLN 117.A N LEU 113.A O no hydrogen 2.868 N/A GLN 118.A N ARG 114.A O no hydrogen 3.040 N/A LYS 119.A N LEU 116.A O no hydrogen 3.102 N/A LYS 119.A NZ SER 85.A O no hydrogen 3.102 N/A ARG 120.A N MET 115.A O no hydrogen 2.836 N/A TRP 121.A N LYS 119.A O no hydrogen 2.948 N/A ALA 124.A N ARG 120.A O no hydrogen 2.913 N/A ALA 125.A N TRP 121.A O no hydrogen 2.996 N/A VAL 126.A N ALA 122.A O no hydrogen 3.295 N/A ASN 127.A N GLU 123.A O no hydrogen 3.370 N/A LEU 128.A N ALA 124.A O no hydrogen 2.901 N/A ALA 129.A N VAL 126.A O no hydrogen 3.330 N/A LYS 130.A N ASN 127.A O no hydrogen 3.440 N/A SER 131.A OG LEU 128.A O no hydrogen 2.725 N/A TRP 133.A NE1 GLN 100.A OE1 no hydrogen 2.806 N/A TYR 134.A N SER 131.A O no hydrogen 3.302 N/A GLN 136.A N ARG 132.A O no hydrogen 2.814 N/A THR 137.A N TRP 133.A O no hydrogen 3.312 N/A THR 137.A OG1 THR 141.A OG1 no hydrogen 3.315 N/A ARG 140.A NE ASN 96.A OD1 no hydrogen 3.188 N/A ARG 140.A NH2 GLU 10.A OE2 no hydrogen 3.366 N/A ARG 140.A NH2 ASN 96.A OD1 no hydrogen 3.056 N/A THR 141.A N THR 137.A O no hydrogen 2.946 N/A THR 141.A OG1 TRP 133.A O no hydrogen 2.732 N/A THR 141.A OG1 THR 137.A O no hydrogen 3.006 N/A THR 141.A OG1 THR 137.A OG1 no hydrogen 3.315 N/A LYS 142.A N PRO 138.A O no hydrogen 3.354 N/A ARG 143.A N ASN 139.A O no hydrogen 3.382 N/A ARG 143.A NE ASP 9.A OD1 no hydrogen 2.900 N/A ARG 143.A NH1 ASP 9.A OD1 no hydrogen 2.899 N/A VAL 144.A N ARG 140.A O no hydrogen 3.035 N/A ILE 145.A N THR 141.A O no hydrogen 2.810 N/A THR 146.A N LYS 142.A O no hydrogen 3.061 N/A THR 146.A OG1 LYS 142.A O no hydrogen 2.709 N/A THR 147.A N ARG 143.A O no hydrogen 3.324 N/A THR 147.A OG1 ARG 143.A O no hydrogen 2.730 N/A PHE 148.A N VAL 144.A O no hydrogen 3.111 N/A ALA 149.A N ILE 145.A O no hydrogen 2.832 N/A THR 150.A N THR 146.A O no hydrogen 3.043 N/A THR 150.A OG1 THR 146.A O no hydrogen 2.770 N/A THR 150.A OG1 THR 152.A OG1 no hydrogen 2.734 N/A GLY 151.A N THR 147.A O no hydrogen 2.818 N/A THR 152.A OG1 THR 150.A OG1 no hydrogen 2.734 N/A THR 152.A OG1 ASP 154.A OD2 no hydrogen 2.955 N/A TYR 156.A OH ASP 9.A OD2 no hydrogen 2.708 N/A LYS 157.A N TRP 153.A O no hydrogen 2.824 N/A LYS 157.A NZ ASP 154.A OD1 no hydrogen 2.913 N/A ASN 158.A N ASP 154.A O no hydrogen 2.751 N/A LEU 159.A N ALA 155.A O no hydrogen 3.454 N/A ARG 160.A N TYR 156.A O no hydrogen 3.058 N/A LYS 161.A N LYS 157.A O no hydrogen 2.914 N/A LYS 162.A N ASN 158.A O no hydrogen 2.813 N/A LYS 162.A NZ ASP 230.A OD1 no hydrogen 2.974 N/A LEU 163.A N LEU 159.A O no hydrogen 2.918 N/A GLU 164.A N ARG 160.A O no hydrogen 2.800 N/A GLN 165.A N LYS 161.A O no hydrogen 2.911 N/A TYR 167.A N LEU 163.A O no hydrogen 2.804 N/A TYR 167.A OH GLU 176.A O no hydrogen 2.873 N/A ASN 168.A N GLU 164.A O no hydrogen 3.324 N/A ARG 169.A N LEU 166.A O no hydrogen 3.304 N/A ARG 169.A NE ASP 190.A OD2 no hydrogen 2.965 N/A ARG 169.A NH2 ASP 190.A OD1 no hydrogen 3.225 N/A ARG 169.A NH2 ASP 190.A OD2 no hydrogen 3.480 N/A TYR 170.A N TYR 167.A O no hydrogen 2.976 N/A TYR 170.A OH ASP 190.A OD2 no hydrogen 2.926 N/A LYS 171.A N TYR 167.A O no hydrogen 3.027 N/A ASP 172.A N LYS 178.A O no hydrogen 3.166 N/A ASP 175.A N ASP 172.A O no hydrogen 3.063 N/A LYS 178.A NZ ASP 172.A OD2 no hydrogen 3.461 N/A ILE 179.A N PHE 215.A O no hydrogen 2.750 N/A ILE 184.A N GLY 180.A O no hydrogen 2.955 N/A GLN 185.A N ILE 181.A O no hydrogen 2.991 N/A GLN 186.A N ASP 182.A O no hydrogen 3.031 N/A GLN 186.A NE2 ASP 190.A OD1 no hydrogen 3.344 N/A PHE 187.A N GLY 183.A O no hydrogen 2.983 N/A CYS 188.A N ILE 184.A O no hydrogen 3.095 N/A CYS 188.A SG ILE 184.A O no hydrogen 3.394 N/A ASP 189.A N GLN 185.A O no hydrogen 2.861 N/A ASP 190.A N GLN 186.A O no hydrogen 2.788 N/A LEU 191.A N PHE 187.A O no hydrogen 3.187 N/A ALA 192.A N ASP 189.A O no hydrogen 2.870 N/A LEU 193.A N CYS 188.A O no hydrogen 2.874 N/A SER 197.A N ASP 194.A O no hydrogen 2.957 N/A SER 197.A OG ASP 194.A O no hydrogen 2.737 N/A LEU 201.A N SER 197.A O no hydrogen 3.432 N/A ILE 202.A N ILE 198.A O no hydrogen 2.843 N/A ILE 203.A N SER 199.A O no hydrogen 3.015 N/A ALA 204.A N VAL 200.A O no hydrogen 2.937 N/A TRP 205.A N LEU 201.A O no hydrogen 3.117 N/A TRP 205.A NE1 ASP 254.A OD2 no hydrogen 2.824 N/A LYS 206.A N ILE 202.A O no hydrogen 3.131 N/A LYS 206.A NZ GLU 245.A OE1 no hydrogen 2.813 N/A PHE 207.A N ILE 203.A O no hydrogen 2.886 N/A ARG 208.A N TRP 205.A O no hydrogen 3.172 N/A ARG 208.A NH1 GLU 226.A OE1 no hydrogen 2.807 N/A ARG 208.A NH1 GLU 226.A OE2 no hydrogen 3.109 N/A ARG 208.A NH2 GLU 226.A OE1 no hydrogen 2.813 N/A ALA 209.A N ALA 204.A O no hydrogen 2.985 N/A ALA 210.A N GLU 219.A OE2 no hydrogen 2.855 N/A GLN 212.A N PHE 262.A O no hydrogen 3.044 N/A GLN 212.A NE2 ALA 263.A O no hydrogen 2.775 N/A SER 216.A N GLU 219.A OE1 no hydrogen 3.399 N/A LYS 217.A N ASN 177.A O no hydrogen 2.824 N/A GLU 219.A N SER 216.A OG no hydrogen 3.087 N/A PHE 220.A N SER 216.A O no hydrogen 3.025 N/A MET 221.A N LYS 217.A O no hydrogen 2.896 N/A ASP 222.A N GLN 218.A O no hydrogen 2.813 N/A GLY 223.A N GLU 219.A O no hydrogen 3.052 N/A MET 224.A N PHE 220.A O no hydrogen 2.925 N/A THR 225.A N MET 221.A O no hydrogen 3.172 N/A THR 225.A OG1 MET 221.A O no hydrogen 2.704 N/A GLU 226.A N ASP 222.A O no hydrogen 3.046 N/A LEU 227.A N GLY 223.A O no hydrogen 3.187 N/A GLY 228.A N THR 225.A O no hydrogen 3.094 N/A CYS 229.A N MET 224.A O no hydrogen 2.784 N/A LEU 235.A N SER 231.A O no hydrogen 3.391 N/A LYS 236.A N ILE 232.A O no hydrogen 3.038 N/A LYS 236.A NZ LEU 191.A O no hydrogen 2.797 N/A ALA 237.A N GLU 233.A O no hydrogen 3.284 N/A GLN 238.A N LEU 235.A O no hydrogen 3.119 N/A ILE 239.A N LEU 235.A O no hydrogen 3.324 N/A LYS 241.A NZ GLN 238.A OE1 no hydrogen 2.810 N/A MET 242.A N GLN 238.A O no hydrogen 3.233 N/A GLU 243.A N ILE 239.A O no hydrogen 2.897 N/A GLN 244.A N PRO 240.A O no hydrogen 2.980 N/A GLU 245.A N LYS 241.A O no hydrogen 3.280 N/A LEU 246.A N GLU 243.A O no hydrogen 3.145 N/A LYS 247.A N GLN 244.A O no hydrogen 3.250 N/A GLU 248.A N GLU 245.A O no hydrogen 3.112 N/A GLY 250.A N GLU 248.A OE2 no hydrogen 2.989 N/A ARG 251.A N GLU 248.A OE1 no hydrogen 3.051 N/A ARG 251.A NE GLU 245.A OE2 no hydrogen 3.398 N/A PHE 252.A N GLU 248.A O no hydrogen 3.076 N/A LYS 253.A N PRO 249.A O no hydrogen 3.027 N/A ASP 254.A N GLY 250.A O no hydrogen 3.353 N/A PHE 255.A N ARG 251.A O no hydrogen 3.127 N/A TYR 256.A N PHE 252.A O no hydrogen 2.784 N/A TYR 256.A OH TRP 311.A O no hydrogen 2.661 N/A GLN 257.A N LYS 253.A O no hydrogen 2.887 N/A PHE 258.A N ASP 254.A O no hydrogen 2.999 N/A THR 259.A N PHE 255.A O no hydrogen 3.114 N/A THR 259.A OG1 PHE 255.A O no hydrogen 2.743 N/A PHE 260.A N GLN 257.A O no hydrogen 3.255 N/A PHE 262.A N PHE 258.A O no hydrogen 2.945 N/A ALA 263.A N THR 259.A O no hydrogen 2.806 N/A LYS 264.A N PHE 260.A O no hydrogen 3.061 N/A LYS 264.A NZ ASN 261.A OD1 no hydrogen 3.255 N/A GLN 268.A N ASN 265.A O no hydrogen 3.214 N/A GLN 268.A NE2 ASP 272.A OD1 no hydrogen 3.534 N/A LEU 271.A N ILE 306.A O no hydrogen 2.903 N/A ALA 276.A N ASP 272.A O no hydrogen 2.838 N/A ILE 277.A N LEU 273.A O no hydrogen 3.040 N/A ALA 278.A N GLU 274.A O no hydrogen 3.367 N/A TYR 279.A N MET 275.A O no hydrogen 3.085 N/A TYR 279.A OH GLN 212.A OE1 no hydrogen 2.692 N/A TRP 280.A N ALA 276.A O no hydrogen 2.882 N/A TRP 280.A NE1 TYR 256.A OH no hydrogen 2.921 N/A ASN 281.A N ILE 277.A O no hydrogen 2.845 N/A LEU 282.A N TYR 279.A O no hydrogen 3.175 N/A VAL 283.A N TYR 279.A O no hydrogen 2.832 N/A LEU 284.A N TRP 280.A O no hydrogen 2.872 N/A ARG 287.A N LEU 284.A O no hydrogen 3.122 N/A ARG 287.A NH2 LEU 246.A O no hydrogen 3.383 N/A PHE 288.A N LEU 284.A O no hydrogen 3.261 N/A LEU 291.A N PHE 288.A O no hydrogen 3.363 N/A TRP 294.A N PHE 290.A O no hydrogen 2.774 N/A ASN 295.A N LEU 291.A O no hydrogen 3.127 N/A ASN 295.A ND2 ASN 281.A OD1 no hydrogen 2.791 N/A LYS 296.A N ASP 292.A O no hydrogen 2.934 N/A PHE 297.A N LEU 293.A O no hydrogen 2.970 N/A LEU 298.A N TRP 294.A O no hydrogen 2.967 N/A LEU 299.A N ASN 295.A O no hydrogen 2.988 N/A HIS 301.A N PHE 297.A O no hydrogen 2.935 N/A HIS 302.A N LEU 298.A O no hydrogen 2.862 N/A HIS 302.A NE2 SER 305.A O no hydrogen 2.800 N/A SER 305.A OG LEU 271.A O no hydrogen 2.953 N/A ILE 306.A N LEU 271.A O no hydrogen 2.770 N/A TRP 311.A N PRO 307.A O no hydrogen 3.086 N/A TRP 311.A NE1 TYR 256.A O no hydrogen 2.827 N/A ASN 312.A N LYS 308.A O no hydrogen 2.999 N/A LEU 313.A N ASP 309.A O no hydrogen 2.972 N/A LEU 314.A N THR 310.A O no hydrogen 3.255 N/A LEU 314.A N TRP 311.A O no hydrogen 3.169 N/A PHE 317.A N LEU 313.A O no hydrogen 2.828 N/A SER 318.A N LEU 314.A O no hydrogen 2.842 N/A SER 318.A OG LEU 315.A O no hydrogen 2.762 N/A THR 319.A N LEU 315.A O no hydrogen 3.106 N/A THR 319.A OG1 LEU 315.A O no hydrogen 3.059 N/A MET 320.A N ASP 316.A O no hydrogen 3.299 N/A ILE 321.A N PHE 317.A O no hydrogen 2.835 N/A ALA 322.A N ASN 327.A OD1 no hydrogen 3.049 N/A MET 325.A N ALA 322.A O no hydrogen 2.952 N/A SER 326.A OG ASP 324.A OD1 no hydrogen 3.492 N/A SER 326.A OG ASP 324.A OD2 no hydrogen 3.301 N/A ASN 327.A ND2 MET 320.A O no hydrogen 2.804 N/A TYR 328.A OH ASP 339.A OD1 no hydrogen 2.694 N/A GLU 331.A N ASP 329.A OD1 no hydrogen 3.471 N/A ILE 338.A N PRO 335.A O no hydrogen 2.952 N/A ASP 339.A N PRO 335.A O no hydrogen 3.027 N/A ASP 340.A N VAL 336.A O no hydrogen 2.784 N/A PHE 341.A N LEU 337.A O no hydrogen 3.088 N/A VAL 342.A N ILE 338.A O no hydrogen 3.050 N/A GLU 343.A N ASP 339.A O no hydrogen 3.115 N/A PHE 344.A N ASP 340.A O no hydrogen 2.967 N/A ALA 345.A N PHE 341.A O no hydrogen 2.798 N/A ARG 346.A N VAL 342.A O no hydrogen 2.903 N/A ARG 346.A NH1 MET 325.A O no hydrogen 3.069 N/A GLN 348.A NE2 PHE 344.A O no hydrogen 3.256 N/A ILE 349.A N ARG 346.A O no hydrogen 2.932 N/A