Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6z6l_LB.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A NE PHE 5.A O no hydrogen 2.827 N/A PHE 5.A N ARG 3.A O no hydrogen 2.870 N/A ARG 9.A NE SER 264.A O no hydrogen 3.320 N/A ARG 9.A NH1 SER 264.A O no hydrogen 2.368 N/A ARG 9.A NH2 GLY 11.A O no hydrogen 2.624 N/A GLY 14.A N SER 12.A OG no hydrogen 2.976 N/A ARG 20.A NE GLN 270.A OE1 no hydrogen 3.289 N/A SER 21.A N TYR 273.A O no hydrogen 2.909 N/A SER 21.A OG ARG 23.A O no hydrogen 2.517 N/A ARG 23.A N SER 21.A OG no hydrogen 3.096 N/A HIS 24.A ND1 TYR 273.A OH no hydrogen 3.036 N/A SER 30.A OG LYS 29.A O no hydrogen 2.682 N/A SER 37.A OG ASP 35.A OD1 no hydrogen 3.102 N/A HIS 41.A N ASN 185.A O no hydrogen 3.278 N/A HIS 41.A ND1 LEU 42.A O no hydrogen 3.203 N/A THR 43.A OG1 GLN 183.A O no hydrogen 2.809 N/A PHE 45.A N LEU 346.A O no hydrogen 2.857 N/A GLY 47.A N LEU 344.A O no hydrogen 2.938 N/A TYR 48.A N GLU 79.A O no hydrogen 2.935 N/A TYR 48.A OH THR 165.A OG1 no hydrogen 3.328 N/A TYR 48.A OH HIS 178.A ND1 no hydrogen 3.021 N/A LYS 49.A N ARG 342.A O no hydrogen 2.822 N/A LYS 49.A NZ VAL 336.A O no hydrogen 2.744 N/A ALA 50.A N ILE 77.A O no hydrogen 3.009 N/A THR 53.A N VAL 75.A O no hydrogen 2.971 N/A ILE 55.A N GLU 73.A O no hydrogen 2.930 N/A VAL 56.A N PHE 366.A O no hydrogen 2.857 N/A ARG 57.A N VAL 71.A O no hydrogen 3.222 N/A ARG 57.A NE GLU 73.A OE2 no hydrogen 2.437 N/A VAL 59.A N LYS 69.A O no hydrogen 3.272 N/A ARG 61.A N ASN 67.A OD1 no hydrogen 2.999 N/A ARG 61.A NE SER 64.A OG no hydrogen 3.185 N/A SER 64.A N ARG 61.A O no hydrogen 3.161 N/A ASN 67.A N SER 64.A O no hydrogen 3.355 N/A LYS 68.A N VAL 59.A O no hydrogen 2.602 N/A LYS 69.A N VAL 66.A O no hydrogen 3.409 N/A VAL 71.A N ARG 57.A O no hydrogen 2.759 N/A GLU 73.A N ILE 55.A O no hydrogen 3.377 N/A VAL 75.A N THR 53.A O no hydrogen 2.917 N/A THR 76.A N LEU 332.A O no hydrogen 2.907 N/A THR 76.A OG1 GLY 334.A O no hydrogen 2.240 N/A ILE 77.A N GLY 51.A O no hydrogen 3.027 N/A VAL 78.A N VAL 330.A O no hydrogen 2.983 N/A GLU 79.A N TYR 48.A O no hydrogen 2.830 N/A THR 80.A N ASP 328.A O no hydrogen 2.660 N/A THR 80.A OG1 ASP 328.A O no hydrogen 2.461 N/A MET 83.A N VAL 204.A O no hydrogen 2.939 N/A VAL 84.A N HIS 164.A O no hydrogen 2.858 N/A VAL 85.A N GLN 202.A O no hydrogen 2.837 N/A VAL 86.A N ILE 162.A O no hydrogen 2.932 N/A GLY 87.A N ILE 162.A O no hydrogen 2.960 N/A ILE 88.A N VAL 104.A O no hydrogen 2.913 N/A VAL 89.A N ARG 160.A O no hydrogen 2.904 N/A GLY 90.A N LYS 102.A O no hydrogen 2.844 N/A TYR 91.A N VAL 158.A O no hydrogen 2.784 N/A TYR 91.A OH GLU 181.A OE1 no hydrogen 2.332 N/A TYR 91.A OH GLU 181.A OE2 no hydrogen 3.211 N/A VAL 92.A N ARG 99.A O no hydrogen 2.925 N/A GLU 93.A N GLN 157.A OE1 no hydrogen 3.179 N/A THR 94.A N GLY 97.A O no hydrogen 2.884 N/A ARG 96.A N THR 94.A OG1 no hydrogen 3.161 N/A GLY 97.A N THR 94.A O no hydrogen 2.943 N/A ARG 99.A N VAL 92.A O no hydrogen 2.931 N/A LYS 102.A N GLY 90.A O no hydrogen 3.106 N/A THR 103.A OG1 ILE 88.A O no hydrogen 3.398 N/A VAL 104.A N ILE 88.A O no hydrogen 2.913 N/A PHE 105.A N TYR 132.A OH no hydrogen 3.204 N/A HIS 108.A ND1 GLU 201.A OE2 no hydrogen 2.811 N/A LYS 114.A N SER 110.A O no hydrogen 3.011 N/A LYS 114.A NZ LYS 126.A O no hydrogen 3.419 N/A LYS 114.A NZ ALA 128.A O no hydrogen 3.348 N/A ARG 115.A N ASP 111.A O no hydrogen 2.811 N/A ARG 116.A N GLU 112.A O no hydrogen 2.997 N/A ARG 116.A NE ALA 177.A O no hydrogen 2.645 N/A ARG 116.A NH2 ALA 177.A O no hydrogen 2.845 N/A PHE 117.A N CYS 113.A O no hydrogen 3.042 N/A TYR 118.A N LYS 114.A O no hydrogen 2.978 N/A LYS 123.A N ASN 120.A OD1 no hydrogen 3.072 N/A SER 124.A OG TRP 121.A O no hydrogen 3.207 N/A LYS 126.A N SER 124.A OG no hydrogen 3.264 N/A LYS 126.A NZ TRP 121.A O no hydrogen 3.209 N/A LYS 126.A NZ SER 124.A O no hydrogen 3.498 N/A LYS 127.A N TYR 118.A OH no hydrogen 2.702 N/A THR 130.A OG1 LYS 127.A O no hydrogen 2.833 N/A CYS 133.A N PHE 129.A O no hydrogen 2.925 N/A CYS 133.A SG PHE 129.A O no hydrogen 3.611 N/A LYS 134.A N THR 130.A O no hydrogen 2.958 N/A LYS 135.A N LYS 131.A O no hydrogen 2.902 N/A TRP 136.A N TYR 132.A O no hydrogen 2.940 N/A TRP 136.A NE1 PHE 105.A O no hydrogen 2.794 N/A GLN 137.A N CYS 133.A O no hydrogen 2.989 N/A ASP 138.A N LYS 134.A O no hydrogen 2.902 N/A GLY 141.A N ASP 138.A OD2 no hydrogen 3.198 N/A LYS 142.A NZ ASP 138.A O no hydrogen 2.751 N/A LYS 143.A N GLU 139.A O no hydrogen 3.103 N/A LYS 143.A NZ GLU 139.A O no hydrogen 2.395 N/A GLN 144.A N ASP 140.A O no hydrogen 3.137 N/A LEU 145.A N GLY 141.A O no hydrogen 2.853 N/A GLU 146.A N LYS 142.A O no hydrogen 3.224 N/A LYS 147.A N LYS 143.A O no hydrogen 3.344 N/A LYS 147.A NZ LYS 143.A O no hydrogen 3.013 N/A ASP 148.A N GLN 144.A O no hydrogen 3.148 N/A PHE 149.A N LEU 145.A O no hydrogen 3.280 N/A SER 150.A N GLU 146.A O no hydrogen 3.272 N/A SER 150.A OG GLU 146.A O no hydrogen 2.976 N/A SER 150.A OG LYS 147.A O no hydrogen 2.903 N/A SER 151.A N LYS 147.A O no hydrogen 2.887 N/A SER 151.A OG LYS 147.A O no hydrogen 3.149 N/A SER 151.A OG ASP 148.A O no hydrogen 2.960 N/A MET 152.A N ASP 148.A O no hydrogen 3.017 N/A LYS 153.A N PHE 149.A O no hydrogen 2.801 N/A GLN 157.A N TYR 91.A O no hydrogen 2.843 N/A VAL 158.A N TYR 91.A O no hydrogen 3.026 N/A ARG 160.A N VAL 89.A O no hydrogen 2.869 N/A ARG 160.A NE GLN 183.A OE1 no hydrogen 3.483 N/A ARG 160.A NH1 GLU 181.A OE1 no hydrogen 3.466 N/A VAL 161.A N ILE 182.A O no hydrogen 2.883 N/A ILE 162.A N GLY 87.A O no hydrogen 2.842 N/A ALA 163.A N MET 180.A O no hydrogen 2.927 N/A HIS 164.A N VAL 84.A O no hydrogen 2.920 N/A HIS 164.A ND1 THR 165.A O no hydrogen 2.417 N/A THR 165.A N HIS 178.A O no hydrogen 2.919 N/A THR 165.A OG1 TYR 48.A OH no hydrogen 3.328 N/A GLN 166.A NE2 PRO 82.A O no hydrogen 2.371 N/A MET 167.A N GLU 112.A OE1 no hydrogen 3.199 N/A ARG 168.A NH1 GLN 166.A OE1 no hydrogen 3.399 N/A LEU 169.A N GLN 166.A O no hydrogen 3.397 N/A GLN 174.A NE2 LYS 176.A O no hydrogen 2.683 N/A ALA 177.A N GLU 112.A O no hydrogen 3.298 N/A HIS 178.A ND1 TYR 48.A OH no hydrogen 3.021 N/A ILE 182.A N VAL 161.A O no hydrogen 2.869 N/A GLN 183.A NE2 ASN 185.A OD1 no hydrogen 3.117 N/A VAL 184.A N ILE 159.A O no hydrogen 3.282 N/A ASN 185.A N HIS 41.A O no hydrogen 3.225 N/A ASN 185.A ND2 PRO 32.A O no hydrogen 2.716 N/A GLY 186.A N ASP 34.A OD1 no hydrogen 2.401 N/A GLU 191.A N THR 188.A OG1 no hydrogen 2.969 N/A LYS 192.A N THR 188.A O no hydrogen 2.907 N/A LYS 192.A NZ ASP 34.A OD2 no hydrogen 2.416 N/A LYS 192.A NZ GLY 187.A O no hydrogen 3.455 N/A LEU 193.A N VAL 189.A O no hydrogen 2.912 N/A ASP 194.A N ALA 190.A O no hydrogen 2.944 N/A TRP 195.A N GLU 191.A O no hydrogen 2.956 N/A ALA 196.A N LYS 192.A O no hydrogen 2.915 N/A ARG 197.A N LEU 193.A O no hydrogen 2.946 N/A ARG 197.A NH1 GLU 146.A OE1 no hydrogen 3.507 N/A GLU 198.A N ASP 194.A O no hydrogen 2.926 N/A ARG 199.A N TRP 195.A O no hydrogen 2.974 N/A GLN 202.A N VAL 85.A O no hydrogen 3.064 N/A VAL 204.A N MET 83.A O no hydrogen 2.842 N/A GLN 208.A N PRO 205.A O no hydrogen 2.942 N/A VAL 209.A N PRO 205.A O no hydrogen 3.066 N/A PHE 210.A N VAL 206.A O no hydrogen 2.858 N/A ASP 213.A N GLN 212.A OE1 no hydrogen 2.628 N/A GLU 214.A N ILE 283.A O no hydrogen 3.112 N/A ILE 216.A N LYS 281.A O no hydrogen 2.874 N/A ASP 217.A N ARG 347.A O no hydrogen 2.897 N/A VAL 218.A N GLU 278.A O no hydrogen 2.906 N/A ILE 219.A N THR 345.A O no hydrogen 2.876 N/A GLY 220.A N ARG 276.A O no hydrogen 2.975 N/A THR 222.A N HIS 274.A O no hydrogen 2.604 N/A THR 222.A OG1 HIS 274.A O no hydrogen 3.227 N/A LYS 225.A N LYS 271.A O no hydrogen 3.020 N/A LYS 225.A NZ LYS 223.A O no hydrogen 3.208 N/A LYS 228.A N GLY 269.A O no hydrogen 2.790 N/A LYS 228.A NZ SER 232.A OG no hydrogen 3.387 N/A ARG 233.A N GLY 229.A O no hydrogen 2.881 N/A ARG 233.A NE GLN 270.A O no hydrogen 2.853 N/A ARG 233.A NH1 ARG 267.A O no hydrogen 3.134 N/A ARG 233.A NH2 ARG 18.A O no hydrogen 2.703 N/A ARG 233.A NH2 GLN 270.A O no hydrogen 3.051 N/A TRP 234.A N VAL 230.A O no hydrogen 2.898 N/A TRP 234.A NE1 ARG 267.A O no hydrogen 3.060 N/A HIS 235.A N THR 231.A O no hydrogen 3.170 N/A LEU 239.A N LEU 247.A O no hydrogen 2.962 N/A THR 243.A OG1 PRO 240.A O no hydrogen 2.772 N/A CYS 252.A SG GLY 254.A O no hydrogen 3.173 N/A ALA 259.A N TRP 256.A O no hydrogen 3.026 N/A GLY 269.A N LYS 228.A O no hydrogen 3.179 N/A GLN 270.A NE2 GLY 272.A O no hydrogen 2.973 N/A LYS 271.A N GLY 226.A O no hydrogen 2.835 N/A LYS 271.A NZ SER 232.A O no hydrogen 2.423 N/A LYS 271.A NZ SER 232.A OG no hydrogen 2.857 N/A TYR 273.A N LYS 223.A O no hydrogen 3.427 N/A TYR 273.A OH HIS 24.A ND1 no hydrogen 3.036 N/A HIS 274.A ND1 LYS 19.A O no hydrogen 2.834 N/A ARG 276.A N GLY 220.A O no hydrogen 2.905 N/A ARG 276.A NH1 HIS 275.A O no hydrogen 3.054 N/A GLU 278.A N VAL 218.A O no hydrogen 2.893 N/A LYS 281.A N ILE 216.A O no hydrogen 2.921 N/A LYS 282.A NZ ASP 213.A O no hydrogen 3.394 N/A ILE 283.A N GLU 214.A O no hydrogen 2.813 N/A TYR 284.A N MET 331.A O no hydrogen 2.819 N/A TYR 284.A OH GLU 73.A OE1 no hydrogen 2.305 N/A TYR 284.A OH GLU 73.A OE2 no hydrogen 3.328 N/A LYS 285.A N MET 331.A O no hydrogen 3.033 N/A GLY 287.A N PHE 329.A O no hydrogen 2.869 N/A TYR 290.A N THR 326.A O no hydrogen 2.819 N/A LEU 291.A N GLY 289.A O no hydrogen 2.965 N/A LEU 297.A N LEU 291.A O no hydrogen 3.402 N/A ASN 300.A ND2 LEU 297.A O no hydrogen 3.423 N/A ASN 301.A N ILE 298.A O no hydrogen 3.313 N/A SER 303.A N ASN 301.A O no hydrogen 2.471 N/A SER 303.A OG LYS 299.A O no hydrogen 2.315 N/A THR 304.A N ASP 307.A OD1 no hydrogen 3.043 N/A THR 304.A OG1 THR 304.A O no hydrogen 2.317 N/A TYR 306.A OH ASP 363.A OD1 no hydrogen 3.404 N/A LEU 308.A N ASP 307.A OD1 no hydrogen 2.775 N/A LYS 311.A NZ ILE 367.A O no hydrogen 2.656 N/A LYS 311.A NZ THR 369.A OG1 no hydrogen 2.874 N/A LYS 311.A NZ GLN 379.A OE1 no hydrogen 3.267 N/A SER 312.A OG TYR 290.A OH no hydrogen 3.212 N/A ASN 314.A N SER 312.A OG no hydrogen 3.098 N/A ASN 314.A ND2 SER 312.A OG no hydrogen 2.878 N/A ASN 314.A ND2 VAL 325.A O no hydrogen 3.098 N/A LEU 316.A N THR 369.A O no hydrogen 3.310 N/A GLY 318.A N PRO 315.A O no hydrogen 3.090 N/A PHE 319.A N GLY 323.A O no hydrogen 2.862 N/A TYR 322.A N PHE 319.A O no hydrogen 3.276 N/A TYR 322.A OH GLU 79.A OE1 no hydrogen 2.292 N/A GLY 323.A N PHE 319.A O no hydrogen 3.218 N/A VAL 325.A N ASN 314.A OD1 no hydrogen 2.413 N/A ASN 327.A ND2 GLU 79.A OE2 no hydrogen 2.838 N/A ASN 327.A ND2 LEU 169.A O no hydrogen 2.383 N/A VAL 330.A N VAL 78.A O no hydrogen 2.843 N/A MET 331.A N LYS 285.A O no hydrogen 2.840 N/A LEU 332.A N THR 76.A O no hydrogen 2.937 N/A LYS 333.A N LYS 282.A O no hydrogen 3.142 N/A LYS 333.A NZ GLU 73.A OE1 no hydrogen 2.808 N/A GLY 334.A N ALA 74.A O no hydrogen 2.734 N/A THR 339.A OG1 LYS 340.A O no hydrogen 2.902 N/A LYS 341.A NZ HIS 321.A O no hydrogen 2.311 N/A ARG 342.A N LYS 49.A O no hydrogen 3.174 N/A LEU 344.A N GLY 47.A O no hydrogen 2.862 N/A THR 345.A N ILE 219.A O no hydrogen 2.930 N/A THR 345.A OG1 GLY 26.A O no hydrogen 3.229 N/A LEU 346.A N PHE 45.A O no hydrogen 2.925 N/A ARG 347.A N ASP 217.A O no hydrogen 2.937 N/A ARG 347.A NH1 LYS 348.A O no hydrogen 3.253 N/A LYS 348.A N THR 43.A O no hydrogen 2.988 N/A LYS 348.A NZ GLU 214.A OE2 no hydrogen 3.141 N/A GLN 353.A NE2 SER 349.A OG no hydrogen 2.938 N/A LYS 355.A NZ VAL 352.A O no hydrogen 2.534 N/A LYS 365.A N VAL 56.A O no hydrogen 2.772 N/A PHE 366.A N VAL 56.A O no hydrogen 3.133 N/A ASP 368.A N HIS 54.A O no hydrogen 3.148 N/A THR 369.A N GLN 379.A OE1 no hydrogen 2.735 N/A THR 369.A OG1 GLN 379.A O no hydrogen 3.124 N/A THR 369.A OG1 GLN 379.A OE1 no hydrogen 2.566 N/A THR 370.A N ASP 368.A OD2 no hydrogen 3.076 N/A THR 370.A OG1 ASP 368.A OD2 no hydrogen 2.429 N/A SER 371.A OG LEU 316.A O no hydrogen 3.490 N/A LYS 372.A NZ ASP 368.A OD2 no hydrogen 2.786 N/A LYS 372.A NZ THR 370.A O no hydrogen 3.168 N/A PHE 373.A N SER 371.A OG no hydrogen 3.086 N/A GLN 379.A N GLU 383.A OE2 no hydrogen 2.564 N/A GLN 379.A NE2 ASP 368.A OD1 no hydrogen 3.443 N/A LYS 384.A N THR 380.A O no hydrogen 2.940 N/A LYS 385.A N MET 381.A O no hydrogen 2.935 N/A LYS 385.A NZ MET 381.A O no hydrogen 3.462 N/A ALA 386.A N GLU 382.A O no hydrogen 2.915 N/A PHE 387.A N GLU 383.A O no hydrogen 2.922 N/A MET 388.A N LYS 384.A O no hydrogen 2.897 N/A GLY 389.A N LYS 385.A O no hydrogen 2.916 N/A LYS 393.A NZ ASP 394.A OD1 no hydrogen 3.551 N/A ARG 395.A N LEU 391.A O no hydrogen 2.875 N/A ILE 396.A N LYS 392.A O no hydrogen 2.913 N/A ALA 397.A N LYS 393.A O no hydrogen 2.895 N/A LYS 398.A N ASP 394.A O no hydrogen 2.930 N/A GLU 399.A N ARG 395.A O no hydrogen 2.984 N/A GLU 400.A N ILE 396.A O no hydrogen 2.889 N/A GLY 401.A N ALA 397.A O no hydrogen 2.898 N/A