Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6zqw_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 1.A N HIS 144.A ND1 no hydrogen 3.530 N/A CYS 3.A SG THR 32.A OG1 no hydrogen 3.322 N/A ARG 9.A NE THR 32.A OG1 no hydrogen 3.396 N/A ARG 9.A NH1 GLU 378.A OE2 no hydrogen 2.698 N/A ARG 9.A NH2 GLU 378.A OE2 no hydrogen 3.069 N/A ILE 12.A N THR 32.A O no hydrogen 3.026 N/A GLY 18.A N MET 15.A O no hydrogen 3.311 N/A VAL 21.A N LEU 294.A O no hydrogen 2.953 N/A ILE 23.A N CYS 292.A O no hydrogen 2.907 N/A LEU 25.A N LEU 290.A O no hydrogen 2.870 N/A GLY 29.A N GLU 26.A O no hydrogen 3.298 N/A CYS 30.A N ASN 8.A O no hydrogen 3.230 N/A CYS 30.A SG VAL 31.A O no hydrogen 3.636 N/A CYS 30.A SG PHE 43.A O no hydrogen 3.250 N/A VAL 31.A N PHE 43.A O no hydrogen 2.959 N/A THR 32.A OG1 ASP 42.A OD1 no hydrogen 2.634 N/A VAL 33.A N LEU 41.A O no hydrogen 2.904 N/A MET 34.A N ILE 12.A O no hydrogen 3.198 N/A THR 40.A OG1 ILE 360.A O no hydrogen 2.615 N/A LEU 41.A N VAL 33.A O no hydrogen 2.902 N/A ASP 42.A N SER 142.A O no hydrogen 2.881 N/A PHE 43.A N VAL 31.A O no hydrogen 2.878 N/A GLU 44.A N LEU 140.A O no hydrogen 2.974 N/A VAL 46.A N ARG 138.A O no hydrogen 2.977 N/A THR 48.A N ILE 285.A O no hydrogen 2.956 N/A THR 49.A N GLU 136.A O no hydrogen 2.914 N/A ALA 50.A N ALA 283.A O no hydrogen 2.923 N/A VAL 56.A N GLY 127.A O no hydrogen 3.124 N/A ARG 57.A NH1 TYR 59.A OH no hydrogen 3.518 N/A TYR 59.A N LEU 125.A O no hydrogen 2.921 N/A CYS 60.A SG GLU 62.A O no hydrogen 3.378 N/A CYS 60.A SG LYS 123.A O no hydrogen 3.114 N/A ASN 64.A N THR 120.A O no hydrogen 2.850 N/A ALA 69.A N CYS 116.A O no hydrogen 2.873 N/A ASP 71.A N VAL 114.A O no hydrogen 2.886 N/A ARG 73.A N SER 112.A O no hydrogen 2.918 N/A ALA 80.A N SER 112.A OG no hydrogen 2.787 N/A LYS 84.A NZ GLU 67.A OE1 no hydrogen 2.619 N/A MET 85.A N LEU 82.A O no hydrogen 3.256 N/A ASP 87.A N LYS 84.A O no hydrogen 3.434 N/A VAL 91.A N ALA 117.A O no hydrogen 2.926 N/A LYS 93.A N THR 115.A O no hydrogen 2.970 N/A ARG 94.A NH2 ALA 80.A O no hydrogen 3.488 N/A GLY 95.A N ILE 113.A O no hydrogen 2.895 N/A VAL 97.A N GLY 111.A O no hydrogen 2.960 N/A ARG 99.A NH2 ASN 103.A O no hydrogen 3.519 N/A ASN 103.A N GLY 100.A O no hydrogen 3.072 N/A GLY 111.A N VAL 97.A O no hydrogen 2.830 N/A SER 112.A N ARG 73.A O no hydrogen 2.874 N/A SER 112.A OG GLY 78.A O no hydrogen 3.231 N/A ILE 113.A N GLY 95.A O no hydrogen 2.885 N/A VAL 114.A N ASP 71.A O no hydrogen 2.909 N/A THR 115.A N LYS 93.A O no hydrogen 2.960 N/A THR 115.A OG1 GLN 254.A OE1 no hydrogen 3.347 N/A CYS 116.A N ALA 69.A O no hydrogen 2.945 N/A ALA 117.A N VAL 91.A O no hydrogen 2.986 N/A LYS 118.A N SER 66.A O no hydrogen 3.057 N/A LYS 118.A NZ GLN 89.A OE1 no hydrogen 2.815 N/A THR 120.A N ASN 64.A O no hydrogen 3.185 N/A THR 120.A OG1 ASN 64.A O no hydrogen 3.245 N/A CYS 121.A SG LYS 123.A O no hydrogen 3.150 N/A LYS 123.A N GLU 62.A O no hydrogen 2.981 N/A LEU 125.A N TYR 59.A O no hydrogen 2.877 N/A THR 126.A N THR 206.A O no hydrogen 2.905 N/A THR 126.A OG1 THR 206.A O no hydrogen 3.538 N/A GLY 127.A N ARG 57.A O no hydrogen 2.860 N/A LYS 128.A N TYR 204.A O no hydrogen 2.885 N/A SER 129.A N ALA 54.A O no hydrogen 3.085 N/A ASN 134.A N GLN 131.A O no hydrogen 3.028 N/A LEU 135.A N PRO 132.A O no hydrogen 3.396 N/A GLU 136.A N THR 49.A O no hydrogen 2.873 N/A TYR 137.A N ILE 170.A O no hydrogen 2.906 N/A VAL 139.A N ILE 168.A O no hydrogen 2.935 N/A LEU 140.A N GLU 44.A O no hydrogen 2.866 N/A VAL 141.A N ALA 166.A O no hydrogen 2.891 N/A SER 142.A N ASP 42.A O no hydrogen 2.897 N/A VAL 143.A N ASN 164.A O no hydrogen 3.185 N/A HIS 144.A N THR 40.A O no hydrogen 3.207 N/A SER 146.A OG ALA 145.A O no hydrogen 2.461 N/A SER 146.A OG VAL 365.A O no hydrogen 2.505 N/A ASN 153.A ND2 GLN 159.A O no hydrogen 2.589 N/A ASP 155.A N ASN 154.A OD1 no hydrogen 2.706 N/A GLU 163.A N GLU 163.A OE1 no hydrogen 2.657 N/A ASN 164.A N ASP 161.A O no hydrogen 2.883 N/A ARG 165.A N ASP 161.A O no hydrogen 3.306 N/A ALA 166.A N VAL 141.A O no hydrogen 2.930 N/A ILE 168.A N VAL 139.A O no hydrogen 2.891 N/A ILE 170.A N TYR 137.A O no hydrogen 2.882 N/A ARG 176.A NH2 GLU 178.A OE1 no hydrogen 3.338 N/A VAL 177.A N MET 189.A O no hydrogen 2.902 N/A VAL 179.A N ILE 187.A O no hydrogen 2.891 N/A LEU 181.A N GLY 185.A O no hydrogen 2.864 N/A SER 186.A OG GLU 180.A OE1 no hydrogen 3.378 N/A ILE 187.A N VAL 179.A O no hydrogen 2.922 N/A SER 188.A N LYS 295.A O no hydrogen 2.951 N/A SER 188.A OG GLU 178.A OE1 no hydrogen 2.383 N/A MET 189.A N VAL 177.A O no hydrogen 2.913 N/A GLU 190.A N ARG 293.A O no hydrogen 2.929 N/A CYS 191.A N PRO 175.A O no hydrogen 3.312 N/A GLU 192.A N LYS 291.A O no hydrogen 2.907 N/A ARG 194.A N GLU 192.A O no hydrogen 2.712 N/A SER 195.A OG ARG 194.A O no hydrogen 2.570 N/A SER 195.A OG HIS 289.A NE2 no hydrogen 2.510 N/A TYR 203.A N VAL 214.A O no hydrogen 2.874 N/A TYR 204.A N LYS 128.A O no hydrogen 2.891 N/A LEU 205.A N TRP 212.A O no hydrogen 2.890 N/A THR 206.A N THR 126.A O no hydrogen 2.881 N/A THR 206.A OG1 HIS 211.A ND1 no hydrogen 3.141 N/A MET 207.A N LYS 210.A O no hydrogen 2.886 N/A LYS 210.A N MET 207.A O no hydrogen 2.907 N/A LYS 210.A NZ ASN 208.A O no hydrogen 2.813 N/A HIS 211.A ND1 THR 206.A OG1 no hydrogen 3.141 N/A TRP 212.A N LEU 205.A O no hydrogen 2.895 N/A LEU 213.A N LEU 274.A O no hydrogen 3.228 N/A VAL 214.A N TYR 203.A O no hydrogen 2.916 N/A ARG 216.A N ASP 201.A OD1 no hydrogen 3.196 N/A ARG 216.A NE LEU 202.A O no hydrogen 3.488 N/A TRP 218.A N ASN 215.A O no hydrogen 3.230 N/A PHE 219.A N ASN 215.A O no hydrogen 2.901 N/A ASP 221.A N TRP 218.A O no hydrogen 3.068 N/A SER 223.A OG SER 223.A O no hydrogen 2.543 N/A TRP 226.A N ASN 238.A O no hydrogen 3.081 N/A ALA 230.A N THR 228.A O no hydrogen 2.975 N/A ASN 233.A N ASN 233.A OD1 no hydrogen 2.370 N/A ASN 238.A N TRP 226.A O no hydrogen 2.821 N/A LYS 240.A NZ TRP 237.A O no hydrogen 3.292 N/A GLU 241.A N GLU 241.A OE1 no hydrogen 2.607 N/A LEU 243.A N LYS 240.A O no hydrogen 3.033 N/A VAL 244.A N GLU 241.A O no hydrogen 3.342 N/A GLU 245.A N VAL 257.A O no hydrogen 2.901 N/A LYS 252.A NZ SER 72.A OG no hydrogen 3.160 N/A VAL 257.A N GLU 245.A O no hydrogen 2.913 N/A LEU 259.A N LEU 243.A O no hydrogen 3.344 N/A SER 261.A OG GLU 62.A OE1 no hydrogen 2.590 N/A GLN 262.A NE2 GLY 260.A O no hydrogen 2.673 N/A VAL 266.A N GLN 262.A O no hydrogen 3.291 N/A HIS 267.A N GLU 263.A O no hydrogen 2.913 N/A HIS 267.A ND1 GLU 263.A O no hydrogen 3.090 N/A ALA 268.A N GLY 264.A O no hydrogen 2.896 N/A ALA 269.A N ALA 265.A O no hydrogen 2.907 N/A LEU 270.A N VAL 266.A O no hydrogen 2.950 N/A SER 278.A OG HIS 211.A NE2 no hydrogen 2.675 N/A ASP 279.A N LYS 282.A O no hydrogen 2.887 N/A LYS 282.A N ASP 279.A O no hydrogen 2.914 N/A ALA 283.A N ALA 50.A O no hydrogen 2.888 N/A THR 284.A N GLU 277.A O no hydrogen 2.908 N/A ILE 285.A N THR 48.A O no hydrogen 2.857 N/A HIS 289.A NE2 SER 195.A OG no hydrogen 2.510 N/A LEU 290.A N LEU 25.A O no hydrogen 2.905 N/A LYS 291.A NZ ASP 427.A O no hydrogen 3.553 N/A CYS 292.A N ILE 23.A O no hydrogen 2.937 N/A ARG 293.A N GLU 190.A O no hydrogen 2.874 N/A ARG 293.A NH2 THR 428.A O no hydrogen 2.911 N/A LEU 294.A N VAL 21.A O no hydrogen 2.839 N/A LYS 295.A N SER 188.A O no hydrogen 2.870 N/A LEU 296.A N THR 19.A O no hydrogen 3.363 N/A LYS 298.A N ASP 297.A OD1 no hydrogen 2.658 N/A LYS 298.A NZ ASP 297.A OD2 no hydrogen 3.163 N/A ARG 300.A N PHE 184.A O no hydrogen 2.905 N/A CYS 309.A SG LYS 341.A O no hydrogen 3.203 N/A THR 310.A N ASP 337.A OD2 no hydrogen 3.341 N/A THR 310.A OG1 ASP 337.A OD2 no hydrogen 2.646 N/A ALA 312.A N ALA 334.A O no hydrogen 2.940 N/A THR 314.A N GLN 332.A O no hydrogen 2.943 N/A ALA 316.A N GLU 330.A O no hydrogen 3.081 N/A THR 322.A N THR 326.A O no hydrogen 3.046 N/A THR 322.A OG1 THR 326.A O no hydrogen 3.022 N/A THR 322.A OG1 THR 326.A OG1 no hydrogen 2.384 N/A GLY 325.A N THR 322.A O no hydrogen 3.322 N/A THR 326.A N THR 322.A OG1 no hydrogen 3.319 N/A THR 326.A OG1 THR 322.A OG1 no hydrogen 2.384 N/A THR 326.A OG1 GLU 378.A OE2 no hydrogen 3.221 N/A ALA 327.A N ILE 379.A O no hydrogen 2.906 N/A VAL 329.A N VAL 377.A O no hydrogen 2.876 N/A LEU 331.A N MET 375.A O no hydrogen 2.896 N/A GLN 332.A N THR 314.A O no hydrogen 2.872 N/A TYR 333.A N SER 373.A O no hydrogen 2.878 N/A ALA 334.A N ALA 312.A O no hydrogen 2.862 N/A GLY 335.A N ALA 371.A O no hydrogen 2.969 N/A CYS 340.A SG GLY 338.A O no hydrogen 3.566 N/A LYS 341.A N ALA 307.A O no hydrogen 2.536 N/A LYS 341.A NZ MET 304.A O no hydrogen 2.916 N/A VAL 342.A N PRO 364.A O no hydrogen 2.983 N/A VAL 345.A N ILE 389.A O no hydrogen 2.912 N/A THR 347.A N TYR 387.A O no hydrogen 2.935 N/A THR 347.A OG1 SER 352.A OG no hydrogen 2.549 N/A THR 347.A OG1 ALA 354.A O no hydrogen 3.317 N/A SER 348.A N THR 347.A OG1 no hydrogen 2.590 N/A ASP 349.A N SER 352.A OG no hydrogen 2.844 N/A THR 350.A OG1 ASP 349.A OD1 no hydrogen 3.441 N/A ASN 351.A N ASP 349.A OD1 no hydrogen 3.054 N/A SER 352.A N ASP 349.A O no hydrogen 3.101 N/A SER 352.A OG THR 347.A OG1 no hydrogen 2.549 N/A SER 352.A OG ASP 349.A O no hydrogen 2.397 N/A ALA 354.A N THR 347.A OG1 no hydrogen 3.231 N/A SER 355.A OG GLY 357.A O no hydrogen 3.331 N/A THR 356.A N ILE 346.A O no hydrogen 3.039 N/A ILE 360.A N GLU 378.A O no hydrogen 3.172 N/A THR 361.A N GLU 378.A O no hydrogen 3.178 N/A ASN 363.A ND2 GLY 303.A O no hydrogen 3.229 N/A VAL 366.A N CYS 340.A O no hydrogen 3.477 N/A THR 367.A OG1 GLU 368.A OE2 no hydrogen 2.613 N/A SER 369.A OG SER 369.A O no hydrogen 2.389 N/A SER 373.A N TYR 333.A O no hydrogen 2.931 N/A SER 373.A OG LYS 374.A O no hydrogen 3.523 N/A MET 375.A N LEU 331.A O no hydrogen 2.910 N/A VAL 377.A N VAL 329.A O no hydrogen 2.900 N/A ILE 379.A N ALA 327.A O no hydrogen 2.911 N/A ASP 380.A N ARG 358.A O no hydrogen 3.328 N/A GLY 384.A N ARG 403.A O no hydrogen 2.907 N/A SER 386.A N TRP 401.A O no hydrogen 2.890 N/A SER 386.A OG THR 347.A O no hydrogen 3.109 N/A TYR 387.A N THR 347.A O no hydrogen 2.884 N/A ILE 388.A N HIS 399.A O no hydrogen 2.888 N/A ILE 389.A N VAL 345.A O no hydrogen 2.913 N/A VAL 390.A N ILE 397.A O no hydrogen 2.906 N/A GLY 391.A N PRO 343.A O no hydrogen 2.971 N/A ILE 397.A N VAL 390.A O no hydrogen 2.915 N/A HIS 399.A N ILE 388.A O no hydrogen 2.901 N/A TRP 401.A N SER 386.A O no hydrogen 2.911 N/A ARG 403.A N GLY 384.A O no hydrogen 2.899 N/A ARG 403.A NH1 PRO 381.A O no hydrogen 3.029 N/A GLY 409.A N SER 406.A OG no hydrogen 2.835 N/A ARG 410.A N SER 406.A O no hydrogen 3.116 N/A ARG 410.A NH2 ASP 380.A OD2 no hydrogen 3.256 N/A ALA 411.A N SER 407.A O no hydrogen 2.898 N/A PHE 412.A N ILE 408.A O no hydrogen 2.887 N/A GLU 413.A N GLY 409.A O no hydrogen 2.922 N/A ALA 414.A N ARG 410.A O no hydrogen 2.890 N/A THR 415.A N ALA 411.A O no hydrogen 2.887 N/A THR 415.A OG1 ALA 411.A O no hydrogen 2.864 N/A MET 416.A N PHE 412.A O no hydrogen 2.910 N/A ARG 417.A N GLU 413.A O no hydrogen 2.910 N/A GLY 418.A N ALA 414.A O no hydrogen 2.877 N/A ALA 419.A N THR 415.A O no hydrogen 2.899 N/A LYS 420.A N MET 416.A O no hydrogen 2.915 N/A ARG 421.A N ARG 417.A O no hydrogen 2.892 N/A ARG 421.A NH2 ASP 10.A OD2 no hydrogen 2.850 N/A MET 422.A N GLY 418.A O no hydrogen 2.884 N/A ALA 423.A N ALA 419.A O no hydrogen 2.900 N/A VAL 424.A N LYS 420.A O no hydrogen 2.911 N/A LEU 425.A N ARG 421.A O no hydrogen 2.952 N/A GLY 426.A N VAL 424.A O no hydrogen 2.818 N/A THR 428.A OG1 ASP 427.A O no hydrogen 2.610 N/A SER 434.A OG VAL 435.A O no hydrogen 3.166 N/A SER 441.A N GLY 437.A O no hydrogen 2.845 N/A SER 441.A OG GLY 437.A O no hydrogen 3.268 N/A SER 441.A OG MET 438.A O no hydrogen 2.477 N/A VAL 442.A N MET 438.A O no hydrogen 2.925 N/A GLY 443.A N PHE 439.A O no hydrogen 2.935 N/A LYS 444.A N ASN 440.A O no hydrogen 2.853 N/A PHE 445.A N SER 441.A O no hydrogen 2.968 N/A VAL 446.A N VAL 442.A O no hydrogen 2.964 N/A HIS 447.A N GLY 443.A O no hydrogen 2.898 N/A GLN 448.A N LYS 444.A O no hydrogen 2.909 N/A GLN 448.A NE2 ASP 22.A OD1 no hydrogen 3.278 N/A VAL 449.A N PHE 445.A O no hydrogen 2.926 N/A PHE 450.A N VAL 446.A O no hydrogen 2.936 N/A PHE 450.A N HIS 447.A O no hydrogen 3.179 N/A GLY 451.A N HIS 447.A O no hydrogen 2.861 N/A PHE 454.A N PHE 450.A O no hydrogen 2.923 N/A LYS 455.A N GLY 451.A O no hydrogen 2.893 N/A LYS 455.A NZ GLU 13.A OE1 no hydrogen 2.806 N/A LYS 455.A NZ GLU 13.A OE2 no hydrogen 3.485 N/A LEU 457.A N ALA 453.A O no hydrogen 2.913 N/A PHE 458.A N PHE 454.A O no hydrogen 3.242 N/A GLY 459.A N LEU 457.A O no hydrogen 2.571 N/A SER 462.A OG THR 465.A OG1 no hydrogen 3.312 N/A SER 462.A OG GLN 466.A OE1 no hydrogen 2.913 N/A PHE 464.A N SER 462.A OG no hydrogen 3.229 N/A THR 465.A N SER 462.A OG no hydrogen 3.109 N/A THR 465.A OG1 SER 462.A OG no hydrogen 3.312 N/A THR 465.A OG1 GLN 466.A OE1 no hydrogen 3.115 N/A GLN 466.A N GLN 466.A OE1 no hydrogen 2.489 N/A ILE 469.A N THR 465.A O no hydrogen 2.914 N/A GLY 470.A N GLN 466.A O no hydrogen 2.899 N/A PHE 471.A N LEU 467.A O no hydrogen 2.908 N/A LEU 472.A N LEU 468.A O no hydrogen 2.917 N/A LEU 473.A N ILE 469.A O no hydrogen 2.894 N/A ILE 474.A N GLY 470.A O no hydrogen 2.903 N/A TRP 475.A N PHE 471.A O no hydrogen 2.917 N/A MET 476.A N LEU 472.A O no hydrogen 2.881 N/A GLY 477.A N LEU 473.A O no hydrogen 2.912 N/A LEU 478.A N ILE 474.A O no hydrogen 2.893 N/A LEU 478.A N TRP 475.A O no hydrogen 3.123 N/A ASN 479.A N TRP 475.A O no hydrogen 3.109 N/A MET 490.A N ALA 486.A O no hydrogen 2.917 N/A GLY 491.A N MET 487.A O no hydrogen 2.894 N/A ILE 492.A N SER 488.A O no hydrogen 2.913 N/A GLY 493.A N PHE 489.A O no hydrogen 2.901 N/A ALA 494.A N MET 490.A O no hydrogen 2.917 N/A MET 495.A N GLY 491.A O no hydrogen 2.892 N/A LEU 496.A N ILE 492.A O no hydrogen 2.920 N/A ILE 497.A N GLY 493.A O no hydrogen 2.909 N/A PHE 498.A N ALA 494.A O no hydrogen 2.908 N/A LEU 499.A N MET 495.A O no hydrogen 2.900 N/A ALA 500.A N LEU 496.A O no hydrogen 2.914 N/A THR 501.A N ILE 497.A O no hydrogen 2.899 N/A THR 501.A OG1 ILE 497.A O no hydrogen 2.389 N/A SER 502.A N PHE 498.A O no hydrogen 3.084 N/A SER 502.A OG LEU 499.A O no hydrogen 3.097 N/A SER 502.A OG VAL 503.A O no hydrogen 3.275 N/A