Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6zwz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 5.A N TYR 251.A OH no hydrogen 2.933 N/A GLY 6.A N GLN 26.A OE1 no hydrogen 2.922 N/A ALA 7.A N SER 4.A OG no hydrogen 3.073 N/A ARG 8.A N SER 4.A O no hydrogen 2.916 N/A ARG 8.A NE PRO 187.A O no hydrogen 2.889 N/A ARG 8.A NH1 ASP 222.A OD1 no hydrogen 2.800 N/A ARG 8.A NH2 PRO 187.A O no hydrogen 3.211 N/A ARG 8.A NH2 ASP 222.A OD2 no hydrogen 3.004 N/A ALA 9.A N PHE 5.A O no hydrogen 2.985 N/A GLU 10.A N ALA 7.A O no hydrogen 3.010 N/A LEU 11.A N ARG 8.A O no hydrogen 3.116 N/A ILE 14.A N LEU 11.A O no hydrogen 3.092 N/A VAL 17.A N HIS 15.A ND1 no hydrogen 3.027 N/A SER 19.A N HIS 15.A O no hydrogen 2.856 N/A SER 19.A OG ALA 9.A O no hydrogen 2.695 N/A LYS 20.A N PRO 16.A O no hydrogen 3.030 N/A LEU 21.A N VAL 17.A O no hydrogen 3.012 N/A LEU 22.A N ALA 18.A O no hydrogen 2.853 N/A ARG 23.A N SER 19.A O no hydrogen 2.940 N/A LEU 24.A N LYS 20.A O no hydrogen 3.094 N/A MET 25.A N LEU 21.A O no hydrogen 2.883 N/A GLN 26.A N LEU 22.A O no hydrogen 3.063 N/A LYS 27.A N ARG 23.A O no hydrogen 2.944 N/A LYS 27.A NZ GLU 84.A OE2 no hydrogen 2.747 N/A LYS 28.A N LEU 24.A O no hydrogen 2.926 N/A LYS 28.A NZ GLY 52.A O no hydrogen 2.829 N/A LYS 28.A NZ ILE 55.A O no hydrogen 2.769 N/A LYS 28.A NZ HIS 83.A O no hydrogen 2.747 N/A LYS 28.A NZ GLU 84.A O no hydrogen 2.821 N/A THR 30.A N MET 25.A O no hydrogen 3.091 N/A THR 30.A OG1 SER 54.A O no hydrogen 2.730 N/A ASN 31.A ND2 ASP 222.A O no hydrogen 2.901 N/A ASN 31.A ND2 ALA 247.A O no hydrogen 3.248 N/A LEU 32.A N THR 30.A OG1 no hydrogen 3.155 N/A CYS 33.A N ILE 224.A O no hydrogen 2.808 N/A CYS 33.A SG MET 57.A O no hydrogen 3.899 N/A LEU 34.A N MET 57.A O no hydrogen 3.013 N/A SER 35.A N VAL 226.A O no hydrogen 2.870 N/A SER 35.A OG ASP 37.A OD1 no hydrogen 3.143 N/A SER 35.A OG ASP 37.A OD2 no hydrogen 2.676 N/A ALA 36.A N LYS 59.A O no hydrogen 3.008 N/A VAL 38.A N ALA 36.A O no hydrogen 3.022 N/A ALA 41.A N ASP 67.A OD1 no hydrogen 2.868 N/A LEU 44.A N LEU 40.A O no hydrogen 3.109 N/A LEU 45.A N ALA 41.A O no hydrogen 2.912 N/A GLN 46.A N ARG 42.A O no hydrogen 2.929 N/A LEU 47.A N GLU 43.A O no hydrogen 2.925 N/A ALA 48.A N LEU 44.A O no hydrogen 2.934 N/A ASP 49.A N LEU 45.A O no hydrogen 2.941 N/A ALA 50.A N GLN 46.A O no hydrogen 3.043 N/A LEU 51.A N LEU 47.A O no hydrogen 2.844 N/A SER 54.A N LEU 51.A O no hydrogen 2.848 N/A SER 54.A OG GLU 241.A OE2 no hydrogen 2.648 N/A ILE 55.A N GLY 52.A O no hydrogen 3.324 N/A CYS 56.A N LEU 32.A O no hydrogen 2.840 N/A CYS 56.A SG LEU 32.A O no hydrogen 3.526 N/A LEU 58.A N.A LEU 86.A O no hydrogen 2.879 N/A LEU 58.A N.B LEU 86.A O no hydrogen 2.854 N/A LYS 59.A N LEU 34.A O no hydrogen 2.756 N/A LYS 59.A NZ SER 35.A OG no hydrogen 3.169 N/A LYS 59.A NZ ASP 90.A OD2 no hydrogen 2.761 N/A THR 60.A N PHE 88.A O no hydrogen 2.811 N/A THR 60.A OG1 PHE 88.A O no hydrogen 3.417 N/A THR 60.A OG1 GLU 89.A OE1 no hydrogen 2.781 N/A VAL 62.A N.A GLU 89.A OE1 no hydrogen 2.969 N/A VAL 62.A N.B GLU 89.A OE1 no hydrogen 2.888 N/A ILE 64.A N HIS 61.A O no hydrogen 3.077 N/A LEU 65.A N.A VAL 62.A O.A no hydrogen 3.124 N/A LEU 65.A N.A VAL 62.A O.B no hydrogen 3.234 N/A LEU 65.A N.B VAL 62.A O.A no hydrogen 3.127 N/A LEU 65.A N.B VAL 62.A O.B no hydrogen 3.235 N/A ASN 66.A N SER 39.A O.A no hydrogen 2.772 N/A ASN 66.A N SER 39.A O.B no hydrogen 2.833 N/A PHE 68.A N LEU 65.A O.A no hydrogen 3.151 N/A VAL 72.A N THR 69.A O no hydrogen 3.086 N/A VAL 72.A N THR 69.A OG1 no hydrogen 3.182 N/A LYS 74.A N LEU 70.A O no hydrogen 2.958 N/A GLU 75.A N ASP 71.A O.A no hydrogen 3.101 N/A GLU 75.A N ASP 71.A O.B no hydrogen 3.002 N/A LEU 76.A N VAL 72.A O no hydrogen 2.934 N/A ILE 77.A N MET 73.A O.A no hydrogen 2.876 N/A ILE 77.A N MET 73.A O.B no hydrogen 2.848 N/A THR 78.A N LYS 74.A O no hydrogen 3.068 N/A THR 78.A OG1 LYS 74.A O no hydrogen 3.222 N/A LEU 79.A N GLU 75.A O no hydrogen 3.215 N/A ALA 80.A N LEU 76.A O no hydrogen 2.877 N/A LYS 81.A N ILE 77.A O no hydrogen 2.857 N/A CYS 82.A N THR 78.A O no hydrogen 2.968 N/A HIS 83.A N LEU 79.A O no hydrogen 2.886 N/A HIS 83.A NE2 ASP 49.A OD1 no hydrogen 2.804 N/A PHE 85.A N ALA 80.A O no hydrogen 3.018 N/A LEU 86.A N CYS 56.A O no hydrogen 3.069 N/A ILE 87.A N ASP 115.A OD2 no hydrogen 2.822 N/A PHE 88.A N LEU 58.A O.A no hydrogen 2.916 N/A PHE 88.A N LEU 58.A O.B no hydrogen 2.832 N/A GLU 89.A N LEU 116.A O no hydrogen 2.926 N/A ASP 90.A N THR 60.A O no hydrogen 2.930 N/A ARG 91.A N GLU 89.A O no hydrogen 2.996 N/A ARG 91.A NH1 ARG 91.A O no hydrogen 2.874 N/A ILE 95.A N ASP 94.A OD1 no hydrogen 2.837 N/A VAL 99.A N ILE 95.A O no hydrogen 3.454 N/A LYS 100.A N.A GLY 96.A O no hydrogen 3.262 N/A LYS 100.A N.B GLY 96.A O no hydrogen 3.259 N/A LYS 100.A NZ.A ASN 97.A OD1 no hydrogen 3.332 N/A LYS 100.A NZ.A GLU 133.A OE1.A no hydrogen 2.494 N/A LYS 100.A NZ.A GLU 133.A OE1.B no hydrogen 2.191 N/A LYS 101.A N ASN 97.A O no hydrogen 2.989 N/A GLN 102.A N THR 98.A O no hydrogen 2.905 N/A TYR 103.A N VAL 99.A O no hydrogen 3.042 N/A TYR 103.A N LYS 100.A O.A no hydrogen 3.212 N/A TYR 103.A N LYS 100.A O.B no hydrogen 3.207 N/A GLU 104.A N LYS 100.A O.A no hydrogen 2.881 N/A GLU 104.A N LYS 100.A O.B no hydrogen 2.886 N/A GLY 105.A N LYS 101.A O no hydrogen 2.756 N/A LYS 109.A N GLY 105.A O no hydrogen 3.177 N/A ALA 111.A N TYR 103.A O no hydrogen 2.874 N/A SER 112.A N LYS 109.A O no hydrogen 2.924 N/A SER 112.A OG LYS 109.A O no hydrogen 2.687 N/A TRP 113.A N ILE 110.A O no hydrogen 3.104 N/A TRP 113.A NE1 PHE 108.A O no hydrogen 2.813 N/A ALA 114.A N ILE 110.A O no hydrogen 2.934 N/A LEU 116.A N ILE 87.A O no hydrogen 3.083 N/A VAL 117.A N GLY 141.A O no hydrogen 3.213 N/A ASN 118.A ND2 ASP 90.A OD1 no hydrogen 2.708 N/A ALA 119.A N LEU 143.A O no hydrogen 2.959 N/A HIS 120.A N PHE 92.A O no hydrogen 2.837 N/A GLY 124.A N VAL 121.A O no hydrogen 2.885 N/A VAL 127.A N GLY 124.A O no hydrogen 3.228 N/A LYS 129.A N SER 125.A O no hydrogen 2.948 N/A GLY 130.A N GLY 126.A O no hydrogen 2.959 N/A LEU 131.A N VAL 127.A O no hydrogen 3.101 N/A GLN 132.A N.A VAL 128.A O no hydrogen 2.802 N/A GLN 132.A N.B VAL 128.A O no hydrogen 2.829 N/A GLU 133.A N.A LYS 129.A O no hydrogen 3.318 N/A GLU 133.A N.B GLY 130.A O no hydrogen 3.197 N/A VAL 134.A N.B LEU 131.A O no hydrogen 3.019 N/A GLY 135.A N.A LEU 131.A O no hydrogen 2.696 N/A GLY 135.A N.B LEU 131.A O no hydrogen 2.749 N/A LEU 136.A N.A GLN 132.A O.A no hydrogen 2.891 N/A LEU 136.A N.A GLN 132.A O.B no hydrogen 3.033 N/A LEU 136.A N.B GLN 132.A O.A no hydrogen 2.827 N/A LEU 136.A N.B GLN 132.A O.B no hydrogen 2.976 N/A HIS 139.A N.A LEU 136.A O.A no hydrogen 2.915 N/A HIS 139.A N.A LEU 136.A O.B no hydrogen 2.948 N/A HIS 139.A N.B LEU 136.A O.A no hydrogen 2.982 N/A HIS 139.A N.B LEU 136.A O.B no hydrogen 3.015 N/A HIS 139.A ND1.A PRO 137.A O.B no hydrogen 3.254 N/A ARG 140.A N.A GLY 135.A O.A no hydrogen 2.997 N/A ARG 140.A N.A GLY 135.A O.B no hydrogen 2.888 N/A ARG 140.A N.B GLY 135.A O.A no hydrogen 3.016 N/A ARG 140.A N.B GLY 135.A O.B no hydrogen 2.910 N/A ARG 140.A NE.A ALA 111.A O no hydrogen 2.974 N/A ARG 140.A NE.B ALA 111.A O no hydrogen 2.973 N/A ARG 140.A NH1.B ALA 111.A O no hydrogen 3.034 N/A ARG 140.A NH2.A ALA 111.A O no hydrogen 3.008 N/A GLY 141.A N ASP 115.A O no hydrogen 3.042 N/A CYS 142.A N PHE 173.A O no hydrogen 2.942 N/A CYS 142.A SG VAL 117.A O no hydrogen 3.887 N/A CYS 142.A SG LEU 143.A O no hydrogen 3.815 N/A LEU 143.A N VAL 117.A O no hydrogen 2.833 N/A LEU 144.A N GLY 176.A O no hydrogen 2.935 N/A ILE 145.A N ALA 119.A O no hydrogen 2.932 N/A ALA 146.A N ILE 178.A O no hydrogen 2.890 N/A GLU 147.A N ILE 178.A O no hydrogen 3.369 N/A SER 149.A OG GLN 207.A OE1 no hydrogen 2.774 N/A THR 151.A N GLY 206.A O no hydrogen 2.928 N/A THR 151.A OG1 GLN 208.A OE1 no hydrogen 3.186 N/A SER 153.A N SER 150.A O no hydrogen 3.190 N/A ALA 155.A N SER 153.A OG no hydrogen 3.103 N/A TYR 159.A N THR 156.A O no hydrogen 3.031 N/A THR 160.A OG1 ALA 146.A O no hydrogen 2.813 N/A ARG 161.A N GLY 157.A O no hydrogen 3.158 N/A ARG 161.A NE ASP 158.A OD1 no hydrogen 3.296 N/A ARG 161.A NH2 ASP 158.A OD1 no hydrogen 2.752 N/A ALA 162.A N ASP 158.A O no hydrogen 2.886 N/A ALA 163.A N TYR 159.A O no hydrogen 3.018 N/A VAL 164.A N THR 160.A O no hydrogen 3.081 N/A ARG 165.A N ARG 161.A O no hydrogen 3.011 N/A MET 166.A N ALA 162.A O no hydrogen 2.949 N/A ALA 167.A N ALA 163.A O no hydrogen 2.997 N/A GLU 168.A N.A VAL 164.A O no hydrogen 2.943 N/A GLU 168.A N.B VAL 164.A O no hydrogen 2.969 N/A GLU 169.A N ARG 165.A O no hydrogen 3.010 N/A HIS 170.A N ALA 167.A O no hydrogen 3.089 N/A HIS 170.A ND1 MET 166.A O no hydrogen 2.981 N/A PHE 173.A N HIS 170.A O no hydrogen 3.009 N/A VAL 174.A N HIS 170.A O no hydrogen 2.859 N/A VAL 175.A N CYS 142.A O no hydrogen 2.847 N/A PHE 177.A N LEU 190.A O no hydrogen 2.846 N/A ILE 178.A N LEU 144.A O no hydrogen 2.904 N/A SER 179.A N LEU 192.A O no hydrogen 2.976 N/A SER 179.A OG SER 181.A O no hydrogen 2.746 N/A GLY 180.A N GLU 147.A OE1 no hydrogen 2.781 N/A SER 181.A OG GLU 147.A OE1 no hydrogen 3.493 N/A SER 181.A OG ARG 182.A O no hydrogen 3.387 N/A ARG 182.A N ARG 219.A O no hydrogen 2.874 N/A ARG 182.A NH2 GLU 2.A OE1 no hydrogen 2.990 N/A VAL 183.A N HIS 191.A NE2 no hydrogen 3.097 N/A SER 184.A N HIS 191.A NE2 no hydrogen 3.255 N/A SER 184.A OG GLU 168.A OE2.B no hydrogen 2.712 N/A LYS 186.A N SER 184.A OG no hydrogen 3.075 N/A GLU 188.A N GLU 188.A OE1 no hydrogen 2.792 N/A PHE 189.A N.A LYS 186.A O no hydrogen 3.256 N/A PHE 189.A N.B LYS 186.A O no hydrogen 3.271 N/A LEU 190.A N VAL 175.A O no hydrogen 2.928 N/A HIS 191.A N ASP 222.A OD2 no hydrogen 2.898 N/A LEU 192.A N PHE 177.A O no hydrogen 2.916 N/A THR 193.A N ILE 223.A O no hydrogen 2.870 N/A THR 193.A OG1 SER 179.A O no hydrogen 2.723 N/A THR 193.A OG1 SER 221.A OG.A no hydrogen 2.692 N/A THR 193.A OG1 SER 221.A OG.B no hydrogen 2.713 N/A GLN 197.A N ASN 210.A O no hydrogen 3.094 N/A GLN 197.A NE2 GLU 199.A O no hydrogen 3.078 N/A LEU 198.A N TYR 243.A OH no hydrogen 3.009 N/A GLN 207.A NE2 ASP 203.A OD1 no hydrogen 3.070 N/A GLN 208.A N SER 149.A O no hydrogen 2.811 N/A TYR 209.A OH ASP 203.A OD1 no hydrogen 3.324 N/A ASN 210.A N GLY 195.A O no hydrogen 2.894 N/A GLU 214.A N SER 211.A OG no hydrogen 3.151 N/A VAL 215.A N.A SER 211.A O no hydrogen 3.029 N/A VAL 215.A N.B SER 211.A O no hydrogen 2.965 N/A ILE 216.A N PRO 212.A O no hydrogen 2.933 N/A GLY 217.A N GLN 213.A O no hydrogen 2.849 N/A LYS 218.A N GLU 214.A O no hydrogen 3.116 N/A ARG 219.A N GLU 214.A O no hydrogen 2.892 N/A ARG 219.A NE GLU 214.A OE2 no hydrogen 2.826 N/A SER 221.A N.A VAL 215.A O.A no hydrogen 2.956 N/A SER 221.A N.A VAL 215.A O.B no hydrogen 3.101 N/A SER 221.A N.B VAL 215.A O.A no hydrogen 2.943 N/A SER 221.A N.B VAL 215.A O.B no hydrogen 3.088 N/A SER 221.A OG.A HIS 191.A O no hydrogen 2.948 N/A SER 221.A OG.A THR 193.A OG1 no hydrogen 2.692 N/A SER 221.A OG.B THR 193.A OG1 no hydrogen 2.713 N/A ASP 222.A N HIS 191.A O no hydrogen 2.910 N/A ILE 223.A N HIS 191.A O no hydrogen 3.033 N/A ILE 224.A N ASN 31.A O no hydrogen 3.057 N/A ILE 225.A N THR 193.A O no hydrogen 2.838 N/A VAL 226.A N CYS 33.A O no hydrogen 2.982 N/A ARG 228.A NH2 GLN 197.A OE1 no hydrogen 2.970 N/A ARG 228.A NH2 GLY 202.A O no hydrogen 3.389 N/A ILE 230.A N GLY 227.A O no hydrogen 2.879 N/A ILE 231.A N GLY 227.A O no hydrogen 2.850 N/A SER 232.A N.A ARG 228.A O no hydrogen 3.059 N/A SER 232.A N.B ARG 228.A O no hydrogen 3.054 N/A SER 232.A OG.B ARG 228.A O no hydrogen 2.713 N/A ALA 233.A N ILE 230.A O no hydrogen 3.131 N/A ARG 236.A NH1 GLU 43.A OE1 no hydrogen 2.922 N/A ARG 236.A NH2 GLU 43.A OE1 no hydrogen 3.185 N/A ARG 236.A NH2 ILE 231.A O no hydrogen 2.879 N/A GLU 238.A N ASP 235.A OD1 no hydrogen 3.022 N/A ALA 239.A N ASP 235.A O no hydrogen 3.073 N/A ALA 240.A N ARG 236.A O no hydrogen 2.935 N/A GLU 241.A N LEU 237.A O no hydrogen 2.982 N/A MET 242.A N.A GLU 238.A O no hydrogen 2.950 N/A MET 242.A N.B GLU 238.A O no hydrogen 2.947 N/A TYR 243.A N ALA 239.A O no hydrogen 3.043 N/A ARG 244.A N ALA 240.A O no hydrogen 2.798 N/A ARG 244.A NE GLU 241.A OE1 no hydrogen 3.464 N/A ARG 244.A NE GLU 241.A OE2 no hydrogen 3.019 N/A ARG 244.A NH1 GLU 29.A O no hydrogen 2.865 N/A ARG 244.A NH2 GLU 241.A OE1 no hydrogen 3.018 N/A LYS 245.A N GLU 241.A O no hydrogen 2.905 N/A ALA 246.A N MET 242.A O.A no hydrogen 3.093 N/A ALA 246.A N MET 242.A O.B no hydrogen 3.027 N/A ALA 247.A N TYR 243.A O no hydrogen 2.962 N/A TRP 248.A N ARG 244.A O no hydrogen 2.874 N/A GLU 249.A N LYS 245.A O no hydrogen 3.004 N/A ALA 250.A N ALA 246.A O no hydrogen 3.110 N/A TYR 251.A N ALA 247.A O no hydrogen 3.041 N/A LEU 252.A N TRP 248.A O no hydrogen 2.893 N/A SER 253.A N GLU 249.A O no hydrogen 2.919 N/A SER 253.A OG GLU 249.A O no hydrogen 3.228 N/A SER 253.A OG GLU 249.A OE1 no hydrogen 2.843 N/A ARG 254.A N ALA 250.A O no hydrogen 3.321 N/A ARG 254.A N TYR 251.A O no hydrogen 3.172 N/A ARG 254.A NE GLU 2.A OE1 no hydrogen 3.101 N/A ARG 254.A NH1 ILE 216.A O no hydrogen 2.820 N/A ARG 254.A NH1 SER 221.A O.A no hydrogen 2.530 N/A ARG 254.A NH1 SER 221.A O.B no hydrogen 2.583 N/A ARG 254.A NH2 GLU 2.A OE2 no hydrogen 3.182 N/A ARG 254.A NH2 ASP 222.A OD1 no hydrogen 3.281 N/A LEU 255.A N TYR 251.A O no hydrogen 3.242 N/A LEU 255.A N LEU 252.A O no hydrogen 3.165 N/A GLY 256.A N LEU 252.A O no hydrogen 2.959 N/A