Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7a5w_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 5.A N ASP 2.A OD1 no hydrogen 2.980 N/A ARG 6.A N ASP 2.A O no hydrogen 3.124 N/A PHE 7.A N LEU 3.A O no hydrogen 2.921 N/A ALA 8.A N ALA 4.A O no hydrogen 2.945 N/A GLU 9.A N ASP 5.A O no hydrogen 2.956 N/A LEU 10.A N ARG 6.A O no hydrogen 2.945 N/A GLU 11.A N PHE 7.A O no hydrogen 2.917 N/A ARG 12.A N ALA 8.A O no hydrogen 2.974 N/A ARG 12.A NH1 GLU 9.A OE1 no hydrogen 2.930 N/A ARG 13.A N GLU 9.A O no hydrogen 2.887 N/A ARG 13.A NH1 GLU 256.A OE2 no hydrogen 2.895 N/A ARG 13.A NH2 GLU 256.A OE1 no hydrogen 2.862 N/A ARG 13.A NH2 GLU 256.A OE2 no hydrogen 3.438 N/A TYR 14.A N LEU 10.A O no hydrogen 2.987 N/A TYR 14.A OH GLU 256.A OE2 no hydrogen 2.532 N/A ASP 15.A N ARG 12.A O no hydrogen 3.218 N/A ALA 16.A N GLU 11.A O no hydrogen 3.029 N/A ARG 17.A N ASP 239.A O no hydrogen 2.772 N/A ARG 17.A NE ASP 239.A OD1 no hydrogen 3.108 N/A ARG 17.A NH1 GLU 37.A OE1 no hydrogen 2.913 N/A ARG 17.A NH1 ARG 38.A O no hydrogen 2.985 N/A ARG 17.A NH2 ARG 38.A O no hydrogen 2.858 N/A ARG 17.A NH2 ASP 239.A OD1 no hydrogen 3.518 N/A ARG 17.A NH2 ASP 239.A OD2 no hydrogen 2.808 N/A LEU 18.A N GLU 11.A OE2 no hydrogen 2.854 N/A GLY 19.A N MET 237.A O.A no hydrogen 2.741 N/A GLY 19.A N MET 237.A O.B no hydrogen 2.669 N/A VAL 20.A N TYR 33.A O no hydrogen 2.807 N/A TYR 21.A N ALA 235.A O no hydrogen 2.955 N/A VAL 22.A N ILE 31.A O no hydrogen 2.831 N/A THR 25.A N THR 28.A O no hydrogen 2.889 N/A THR 25.A OG1 THR 27.A OG1 no hydrogen 3.209 N/A THR 25.A OG1 THR 28.A OG1 no hydrogen 2.758 N/A THR 27.A N THR 25.A OG1 no hydrogen 2.980 N/A THR 27.A OG1 THR 25.A OG1 no hydrogen 3.209 N/A THR 28.A N THR 25.A O no hydrogen 3.365 N/A THR 28.A OG1 THR 25.A OG1 no hydrogen 2.758 N/A ILE 31.A N VAL 22.A O no hydrogen 2.985 N/A TYR 33.A N VAL 20.A O no hydrogen 2.869 N/A TYR 33.A OH GLU 11.A OE1 no hydrogen 2.635 N/A ARG 34.A NE GLU 11.A OE2 no hydrogen 2.753 N/A ARG 34.A NH1 GLU 37.A OE2 no hydrogen 2.879 N/A ARG 34.A NH2 GLU 11.A OE1 no hydrogen 2.996 N/A GLU 37.A N ARG 34.A O no hydrogen 3.075 N/A ARG 38.A NH1 VAL 134.A O no hydrogen 2.879 N/A ARG 38.A NH1 THR 155.A OG1 no hydrogen 2.829 N/A ARG 38.A NH2 VAL 134.A O no hydrogen 3.022 N/A PHE 39.A N THR 156.A O no hydrogen 2.853 N/A PHE 41.A N ASP 154.A O no hydrogen 3.126 N/A SER 43.A OG SER 101.A OG.B no hydrogen 2.737 N/A THR 44.A N PHE 41.A O no hydrogen 3.147 N/A THR 44.A OG1 PHE 41.A O no hydrogen 2.736 N/A PHE 45.A N CYS 42.A O no hydrogen 3.416 N/A LYS 46.A N SER 43.A O no hydrogen 2.992 N/A LYS 46.A NZ SER 43.A OG no hydrogen 2.779 N/A LYS 46.A NZ SER 101.A O.A no hydrogen 2.958 N/A LYS 46.A NZ SER 101.A O.B no hydrogen 2.595 N/A LYS 46.A NZ GLU 141.A OE2 no hydrogen 2.814 N/A ALA 47.A N THR 44.A O no hydrogen 3.351 N/A LEU 49.A N PHE 45.A O no hydrogen 2.846 N/A VAL 50.A N LYS 46.A O no hydrogen 3.069 N/A ALA 51.A N ALA 47.A O no hydrogen 3.063 N/A ALA 52.A N PRO 48.A O no hydrogen 2.796 N/A VAL 53.A N LEU 49.A O no hydrogen 3.037 N/A LEU 54.A N VAL 50.A O no hydrogen 2.861 N/A HIS 55.A N ALA 51.A O no hydrogen 2.752 N/A GLN 56.A N ALA 52.A O no hydrogen 3.065 N/A GLN 56.A NE2 LEU 113.A O no hydrogen 3.137 N/A ASN 57.A N LEU 54.A O no hydrogen 3.406 N/A ASN 57.A ND2 VAL 53.A O no hydrogen 2.892 N/A HIS 61.A N PRO 58.A O no hydrogen 3.003 N/A HIS 61.A NE2 ASP 112.A OD2 no hydrogen 2.645 N/A LEU 62.A N LEU 59.A O no hydrogen 2.950 N/A ASP 63.A N THR 60.A O no hydrogen 3.012 N/A LYS 64.A N HIS 61.A O no hydrogen 2.947 N/A ILE 66.A N MET 88.A O no hydrogen 2.824 N/A TYR 68.A OH ALA 80.A O no hydrogen 2.708 N/A THR 69.A N ASP 72.A OD2 no hydrogen 2.828 N/A ASP 71.A N THR 69.A OG1 no hydrogen 3.016 N/A ASP 72.A N THR 69.A O no hydrogen 2.926 N/A ILE 73.A N SER 70.A O no hydrogen 3.120 N/A ARG 74.A NH2 GLU 143.A OE1 no hydrogen 3.505 N/A ARG 74.A NH2 GLU 143.A OE2 no hydrogen 2.779 N/A SER 77.A OG SER 75.A O no hydrogen 2.738 N/A SER 77.A OG ASP 102.A OD1 no hydrogen 3.436 N/A SER 77.A OG THR 104.A OG1 no hydrogen 2.695 N/A VAL 79.A N ASP 102.A OD2 no hydrogen 2.838 N/A ALA 80.A N ASP 102.A OD2 no hydrogen 2.807 N/A GLN 81.A N SER 77.A O no hydrogen 3.244 N/A GLN 82.A N VAL 79.A O no hydrogen 2.948 N/A HIS 83.A N ALA 80.A O no hydrogen 3.005 N/A HIS 83.A ND1 THR 86.A OG1 no hydrogen 3.183 N/A THR 86.A N HIS 83.A O no hydrogen 3.267 N/A THR 86.A OG1 HIS 83.A ND1 no hydrogen 3.183 N/A THR 86.A OG1 HIS 83.A O no hydrogen 3.461 N/A THR 86.A OG1 GLY 87.A O no hydrogen 2.742 N/A GLY 87.A N HIS 83.A O no hydrogen 2.886 N/A MET 88.A N ILE 66.A O no hydrogen 2.951 N/A THR 89.A N GLN 92.A OE1 no hydrogen 2.859 N/A THR 89.A OG1 LEU 62.A O no hydrogen 3.469 N/A ILE 90.A N LYS 64.A O no hydrogen 2.848 N/A GLY 91.A N LEU 62.A O no hydrogen 2.824 N/A GLN 92.A N THR 89.A OG1 no hydrogen 3.102 N/A LEU 93.A N THR 89.A O no hydrogen 2.835 N/A CYS 94.A N ILE 90.A O no hydrogen 2.897 N/A CYS 94.A SG ILE 90.A O no hydrogen 3.419 N/A ASP 95.A N GLY 91.A O no hydrogen 2.958 N/A ALA 96.A N GLN 92.A O no hydrogen 2.923 N/A ALA 97.A N LEU 93.A O no hydrogen 2.814 N/A ILE 98.A N CYS 94.A O no hydrogen 3.070 N/A ARG 99.A N ASP 95.A O no hydrogen 2.812 N/A ARG 99.A NE.A ASP 95.A OD1 no hydrogen 2.718 N/A ARG 99.A NE.A ASP 95.A OD2 no hydrogen 3.241 N/A ARG 99.A NE.B ARG 188.A O no hydrogen 3.096 N/A ARG 99.A NH1.B ASP 95.A OD1 no hydrogen 2.898 N/A ARG 99.A NH2.A ASP 95.A OD1 no hydrogen 2.772 N/A TYR 100.A N ALA 96.A O no hydrogen 2.961 N/A SER 101.A OG.B SER 43.A OG no hydrogen 2.737 N/A ASP 102.A N ALA 96.A O no hydrogen 3.092 N/A GLY 103.A N ILE 76.A O no hydrogen 2.842 N/A THR 104.A N SER 77.A OG no hydrogen 3.028 N/A THR 104.A OG1 ASP 72.A O no hydrogen 3.432 N/A THR 104.A OG1 SER 77.A OG no hydrogen 2.695 N/A ALA 105.A N ASP 102.A OD1 no hydrogen 2.796 N/A ALA 106.A N ASP 102.A O no hydrogen 3.002 N/A ASN 107.A N GLY 103.A O no hydrogen 2.943 N/A ASN 107.A ND2 GLU 141.A O no hydrogen 2.970 N/A LEU 108.A N THR 104.A O no hydrogen 2.831 N/A LEU 109.A N ALA 105.A O no hydrogen 2.896 N/A LEU 110.A N ALA 106.A O no hydrogen 2.855 N/A ALA 111.A N ASN 107.A O no hydrogen 2.975 N/A ASP 112.A N LEU 108.A O no hydrogen 2.902 N/A LEU 113.A N LEU 109.A O no hydrogen 2.978 N/A LEU 113.A N LEU 110.A O no hydrogen 3.140 N/A GLY 114.A N LEU 110.A O no hydrogen 3.030 N/A GLY 115.A N ALA 111.A O no hydrogen 2.834 N/A ALA 122.A N GLY 118B.A O no hydrogen 2.809 N/A PHE 123.A N GLY 119C.A O no hydrogen 2.896 N/A THR 124.A N THR 120D.A O no hydrogen 2.975 N/A THR 124.A OG1 LEU 137.A O no hydrogen 3.102 N/A THR 124.A OG1 THR 120D.A O no hydrogen 3.012 N/A GLY 125.A N ALA 121.A O no hydrogen 2.891 N/A TYR 126.A N ALA 122.A O no hydrogen 2.973 N/A LEU 127.A N PHE 123.A O no hydrogen 3.130 N/A ARG 128.A N THR 124.A O no hydrogen 2.938 N/A ARG 128.A NH1 ASP 132.A O no hydrogen 2.771 N/A ARG 128.A NH1 SER 135.A O no hydrogen 2.840 N/A ARG 128.A NH2 SER 135.A O no hydrogen 3.031 N/A SER 129.A N GLY 125.A O no hydrogen 2.913 N/A SER 129.A OG TYR 126.A O no hydrogen 2.585 N/A LEU 130.A N TYR 126.A O no hydrogen 3.302 N/A LEU 130.A N LEU 127.A O no hydrogen 2.990 N/A GLY 131.A N ARG 128.A O no hydrogen 2.948 N/A ASP 132.A N LEU 127.A O no hydrogen 3.081 N/A VAL 134.A N ASP 132.A OD1 no hydrogen 2.933 N/A SER 135.A N ASP 132.A OD1 no hydrogen 2.870 N/A SER 135.A OG ASP 132.A OD1 no hydrogen 3.177 N/A SER 135.A OG ASP 132.A OD2 no hydrogen 2.478 N/A SER 135.A OG THR 156.A OG1 no hydrogen 2.631 N/A ARG 136.A N THR 155.A O no hydrogen 2.944 N/A ARG 136.A NE ASP 138.A OD1 no hydrogen 3.457 N/A ARG 136.A NE ASP 138.A OD2 no hydrogen 2.903 N/A ARG 136.A NH2 ASP 138.A OD1 no hydrogen 2.824 N/A LEU 137.A N THR 124.A OG1 no hydrogen 2.915 N/A ASP 138.A N ASP 154.A OD1 no hydrogen 2.707 N/A ALA 139.A N ASP 154.A OD1 no hydrogen 2.930 N/A GLU 141.A N ASN 107.A OD1 no hydrogen 2.899 N/A LEU 144.A N GLU 140.A O no hydrogen 3.037 N/A ASN 145.A N PRO 142.A O no hydrogen 3.080 N/A ASN 145.A ND2 GLU 141.A OE1 no hydrogen 2.730 N/A ASN 145.A ND2 PRO 142.A O no hydrogen 2.986 N/A ARG 146.A N GLU 143.A O no hydrogen 2.988 N/A ASN 147.A ND2 ASP 154.A OD2 no hydrogen 2.698 N/A ASP 151.A N PRO 148.A O no hydrogen 3.169 N/A ARG 153.A N ASP 151.A OD1 no hydrogen 2.961 N/A ARG 153.A NE ASP 151.A OD1 no hydrogen 3.081 N/A ARG 153.A NE ASP 151.A OD2 no hydrogen 3.165 N/A ARG 153.A NH2 ASP 151.A OD2 no hydrogen 2.794 N/A ASP 154.A N ASP 138.A OD2 no hydrogen 3.155 N/A THR 155.A OG1 GLU 152.A O no hydrogen 2.630 N/A THR 156.A N PHE 39.A O no hydrogen 2.930 N/A THR 156.A OG1 SER 135.A OG no hydrogen 2.631 N/A THR 156.A OG1 THR 157.A O no hydrogen 3.492 N/A THR 157.A OG1 ALA 35.A O no hydrogen 3.479 N/A HIS 159.A N ALA 35.A O no hydrogen 2.903 N/A HIS 159.A ND1 ASP 36.A OD1 no hydrogen 2.832 N/A ALA 160.A N THR 157.A OG1 no hydrogen 2.973 N/A ILE 161.A N THR 157.A O no hydrogen 2.986 N/A ALA 162.A N PRO 158.A O no hydrogen 2.953 N/A LEU 163.A N HIS 159.A O no hydrogen 3.053 N/A VAL 164.A N ALA 160.A O no hydrogen 2.925 N/A LEU 165.A N ILE 161.A O no hydrogen 2.872 N/A GLN 166.A N ALA 162.A O no hydrogen 2.797 N/A GLN 167.A N LEU 163.A O no hydrogen 3.070 N/A GLN 167.A NE2 LEU 130.A O no hydrogen 2.815 N/A GLN 167.A NE2 LEU 163.A O no hydrogen 3.552 N/A LEU 168.A N VAL 164.A O no hydrogen 2.980 N/A VAL 169.A N LEU 165.A O no hydrogen 2.914 N/A LEU 170.A N GLN 166.A O no hydrogen 2.921 N/A GLY 171.A N GLN 166.A O no hydrogen 2.885 N/A ALA 173.A N GLN 167.A O no hydrogen 3.202 N/A LYS 178.A N ASP 177.A OD1 no hydrogen 2.843 N/A LYS 178.A NZ LEU 54.A O no hydrogen 2.798 N/A LYS 178.A NZ ASN 57.A O no hydrogen 2.874 N/A ARG 179.A N PRO 175.A O no hydrogen 2.860 N/A ARG 179.A NE LEU 174.A O no hydrogen 3.313 N/A ARG 179.A NH2 LEU 174.A O no hydrogen 2.831 N/A ALA 180.A N PRO 176.A O no hydrogen 2.995 N/A LEU 181.A N ASP 177.A O no hydrogen 3.297 N/A LEU 182.A N LYS 178.A O no hydrogen 3.151 N/A THR 183.A N ARG 179.A O no hydrogen 2.917 N/A THR 183.A OG1 ARG 179.A O no hydrogen 2.896 N/A ASP 184.A N ALA 180.A O no hydrogen 2.869 N/A TRP 185.A N LEU 181.A O no hydrogen 3.027 N/A MET 186.A N LEU 182.A O no hydrogen 3.071 N/A ALA 187.A N THR 183.A O no hydrogen 2.765 N/A ARG 188.A N ASP 184.A O no hydrogen 3.057 N/A ARG 188.A N TRP 185.A O no hydrogen 3.265 N/A ARG 188.A NE ASP 184.A OD1 no hydrogen 3.151 N/A ARG 188.A NE ASP 184.A OD2 no hydrogen 3.229 N/A ARG 188.A NH2 ASP 95.A OD2 no hydrogen 3.306 N/A ARG 188.A NH2 ASP 184.A OD2 no hydrogen 3.242 N/A ASN 189.A N MET 186.A O no hydrogen 3.227 N/A ASN 189.A ND2 ASP 208.A O no hydrogen 2.954 N/A THR 191.A N ASN 189.A OD1 no hydrogen 3.041 N/A THR 191.A OG1 ARG 99.A O no hydrogen 3.031 N/A THR 191.A OG1 ASN 189.A OD1 no hydrogen 2.827 N/A ALA 193.A N THR 190.A O no hydrogen 3.065 N/A ARG 195.A N GLY 192.A O no hydrogen 2.951 N/A ARG 195.A NE GLU 251.A OE2 no hydrogen 2.759 N/A ARG 195.A NH1 GLY 211.A O no hydrogen 2.823 N/A ARG 195.A NH1 THR 212.A OG1 no hydrogen 3.264 N/A ARG 195.A NH1 ASN 219.A O no hydrogen 2.933 N/A ARG 195.A NH2 THR 212.A OG1 no hydrogen 2.817 N/A ARG 195.A NH2 GLU 251.A OE2 no hydrogen 3.355 N/A ILE 196.A N ASP 220.A OD2 no hydrogen 2.929 N/A ARG 197.A NE ARG 197.A O no hydrogen 2.830 N/A ARG 197.A NH1 TRP 204.A O no hydrogen 2.776 N/A ARG 197.A NH2 PHE 200.A O no hydrogen 2.994 N/A ARG 197.A NH2 PRO 201.A O no hydrogen 2.824 N/A ARG 197.A NH2 TRP 204.A O no hydrogen 3.043 N/A ALA 198.A N ARG 195.A O no hydrogen 2.972 N/A GLY 199.A N ILE 196.A O no hydrogen 2.873 N/A PHE 200.A N ARG 197.A O no hydrogen 3.332 N/A TRP 204.A N PRO 201.A O no hydrogen 2.904 N/A LYS 205.A N TRP 225.A O no hydrogen 2.956 N/A ILE 207.A N VAL 223.A O no hydrogen 2.886 N/A LYS 209.A N ILE 221.A O no hydrogen 2.826 N/A LYS 209.A NZ SER 101.A OG.A no hydrogen 2.688 N/A LYS 209.A NZ SER 101.A OG.B no hydrogen 3.071 N/A LYS 209.A NZ THR 210.A O no hydrogen 2.801 N/A GLY 211.A N ASN 219.A O no hydrogen 2.991 N/A GLY 213.A N ARG 217.A O no hydrogen 2.936 N/A ASP 214.A N ASN 145.A O no hydrogen 3.096 N/A TYR 215.A N TYR 245.A O no hydrogen 2.798 N/A ARG 217.A N ASP 214.A O no hydrogen 3.141 N/A ARG 217.A NH1 ASN 145.A O no hydrogen 3.226 N/A ARG 217.A NH1 ASN 147.A O no hydrogen 2.865 N/A ARG 217.A NH2 ASN 147.A O no hydrogen 2.870 N/A ALA 218.A N SER 238.A O no hydrogen 3.019 N/A ASN 219.A N GLY 211.A O no hydrogen 2.760 N/A ASN 219.A ND2 ALA 40.A O no hydrogen 2.848 N/A ASN 219.A ND2 PHE 41.A O no hydrogen 2.971 N/A ASP 220.A N VAL 236.A O no hydrogen 2.798 N/A ILE 221.A N LYS 209.A O no hydrogen 2.971 N/A ALA 222.A N VAL 234.A O no hydrogen 2.801 N/A VAL 223.A N ILE 207.A O no hydrogen 2.886 N/A VAL 224.A N TYR 232.A O no hydrogen 2.757 N/A TRP 225.A N LYS 205.A O no hydrogen 2.835 N/A SER 226.A N VAL 230.A O no hydrogen 2.828 N/A SER 226.A OG THR 228.A OG1 no hydrogen 2.857 N/A THR 228.A N SER 226.A OG no hydrogen 3.124 N/A THR 228.A OG1 SER 226.A OG no hydrogen 2.857 N/A GLY 229.A N SER 226.A O no hydrogen 2.806 N/A VAL 230.A N SER 226.A OG no hydrogen 3.026 N/A TYR 232.A N VAL 224.A O no hydrogen 2.863 N/A VAL 234.A N ALA 222.A O no hydrogen 2.819 N/A ALA 235.A N TYR 21.A O no hydrogen 2.967 N/A VAL 236.A N ASP 220.A O no hydrogen 2.901 N/A MET 237.A N.A GLY 19.A O no hydrogen 2.788 N/A MET 237.A N.B GLY 19.A O no hydrogen 2.789 N/A SER 238.A N ASN 219.A OD1 no hydrogen 3.311 N/A SER 238.A OG ALA 218.A O no hydrogen 2.715 N/A ASP 239.A N ARG 17.A O no hydrogen 2.996 N/A ARG 240.A N TYR 215.A O no hydrogen 2.824 N/A ARG 240.A NE TYR 14.A O no hydrogen 3.077 N/A ARG 240.A NE ASP 15.A O no hydrogen 3.370 N/A ARG 240.A NH1 GLU 248.A O no hydrogen 2.775 N/A ARG 240.A NH2 TYR 14.A O no hydrogen 2.970 N/A GLY 243.A N ARG 240.A O no hydrogen 3.037 N/A GLY 244.A N ALA 241.A O no hydrogen 3.042 N/A ALA 247.A N GLY 244.A O no hydrogen 3.070 N/A LEU 253.A N ARG 250.A O no hydrogen 3.196 N/A ALA 255.A N GLU 251.A O no hydrogen 3.098 N/A GLU 256.A N ALA 252.A O no hydrogen 2.877 N/A ALA 257.A N LEU 253.A O no hydrogen 2.869 N/A ALA 258.A N LEU 254.A O no hydrogen 2.906 N/A THR 259.A N ALA 255.A O no hydrogen 2.883 N/A THR 259.A OG1 ALA 255.A O no hydrogen 2.892 N/A ALA 261.A N ALA 258.A O no hydrogen 2.762 N/A GLY 262.A N THR 259.A O no hydrogen 2.850 N/A VAL 263.A N VAL 260.A O no hydrogen 3.034 N/A LEU 264.A N VAL 260.A O no hydrogen 2.979 N/A ALA 265.A N ALA 261.A O no hydrogen 2.855 N/A GLY 118B.A N GLY 115.A O no hydrogen 3.330 N/A