Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7bx1_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 6.A N PRO 3.A O no hydrogen 2.851 N/A LEU 7.A N PRO 3.A O no hydrogen 3.251 N/A ASN 9.A N LEU 7.A O no hydrogen 2.786 N/A GLU 11.A N GLU 8.A O no hydrogen 3.253 N/A GLU 13.A N.A LEU 50.A O no hydrogen 3.027 N/A GLU 13.A N.B LEU 50.A O no hydrogen 3.044 N/A THR 14.A OG1 GLU 13.A OE1.B no hydrogen 3.570 N/A ILE 15.A N ALA 48.A O no hydrogen 2.736 N/A TYR 16.A OH HIS 45.A ND1 no hydrogen 2.770 N/A PHE 17.A N PHE 46.A O no hydrogen 3.188 N/A GLN 18.A N SER 279.A O no hydrogen 2.824 N/A GLN 18.A NE2 TYR 16.A OH no hydrogen 2.827 N/A THR 19.A N ARG 44.A O no hydrogen 2.977 N/A ASN 20.A N VAL 281.A O no hydrogen 2.877 N/A THR 22.A N LYS 42.A O no hydrogen 3.149 N/A THR 22.A OG1 ASN 20.A O no hydrogen 2.779 N/A TYR 23.A OH LYS 113.A O no hydrogen 2.701 N/A ILE 24.A N THR 40.A O no hydrogen 2.878 N/A SER 26.A OG ILE 28.A O no hydrogen 2.492 N/A SER 26.A OG GLN 66.A OE1 no hydrogen 3.328 N/A ILE 28.A N SER 26.A OG no hydrogen 3.211 N/A HIS 29.A N.A VAL 212.A O.A no hydrogen 3.091 N/A HIS 29.A N.A VAL 212.A O.B no hydrogen 3.067 N/A HIS 29.A N.B VAL 212.A O.A no hydrogen 3.086 N/A HIS 29.A N.B VAL 212.A O.B no hydrogen 3.063 N/A LYS 37.A NZ PRO 31.A O no hydrogen 3.537 N/A ASP 39.A N ILE 67.A O no hydrogen 3.090 N/A THR 40.A OG1 GLN 66.A OE1 no hydrogen 2.560 N/A VAL 41.A N LEU 65.A O no hydrogen 2.948 N/A LYS 42.A N THR 22.A O no hydrogen 2.836 N/A ILE 43.A N VAL 63.A O no hydrogen 2.871 N/A ARG 44.A N THR 19.A OG1 no hydrogen 2.771 N/A HIS 45.A N VAL 61.A O no hydrogen 2.688 N/A HIS 45.A ND1 TYR 16.A OH no hydrogen 2.770 N/A PHE 46.A N PHE 17.A O no hydrogen 3.110 N/A PHE 47.A N LEU 59.A O no hydrogen 2.782 N/A ALA 48.A N ILE 15.A O no hydrogen 2.724 N/A LEU 49.A N LEU 57.A O.A no hydrogen 3.186 N/A LEU 49.A N LEU 57.A O.B no hydrogen 2.895 N/A LEU 50.A N GLU 13.A O.A no hydrogen 2.692 N/A LEU 50.A N GLU 13.A O.B no hydrogen 2.747 N/A HIS 51.A N LEU 54.A O no hydrogen 2.903 N/A HIS 51.A ND1 GLU 87.A OE1 no hydrogen 2.629 N/A GLN 52.A N GLU 11.A O no hydrogen 3.243 N/A GLN 52.A NE2 GLU 11.A OE1 no hydrogen 3.505 N/A LEU 54.A N HIS 51.A O no hydrogen 3.134 N/A VAL 56.A N.A LEU 49.A O no hydrogen 2.913 N/A VAL 56.A N.B LEU 49.A O no hydrogen 2.922 N/A GLY 58.A N ASP 82.A O no hydrogen 2.896 N/A LEU 59.A N PHE 47.A O no hydrogen 2.794 N/A GLU 60.A N LYS 80.A O no hydrogen 2.833 N/A VAL 61.A N HIS 45.A O no hydrogen 2.881 N/A PHE 62.A N TYR 77.A O no hydrogen 2.801 N/A VAL 63.A N ILE 43.A O no hydrogen 2.829 N/A TYR 64.A N TYR 75.A O no hydrogen 2.747 N/A LEU 65.A N VAL 41.A O no hydrogen 2.769 N/A GLN 66.A N GLU 73.A O no hydrogen 2.835 N/A GLN 66.A NE2 SER 26.A OG no hydrogen 3.344 N/A ILE 67.A N ASP 39.A O no hydrogen 2.701 N/A TYR 68.A N PHE 71.A O no hydrogen 2.855 N/A VAL 72.A N THR 125.A O no hydrogen 2.919 N/A GLU 73.A N GLN 66.A O no hydrogen 2.865 N/A LYS 74.A N ASN 127.A O no hydrogen 2.889 N/A LYS 74.A NZ ILE 105.A O no hydrogen 2.724 N/A LYS 74.A NZ TYR 107.A O no hydrogen 3.203 N/A TYR 75.A N TYR 64.A O no hydrogen 2.803 N/A VAL 76.A N ARG 129.A O no hydrogen 2.682 N/A TYR 77.A N PHE 62.A O no hydrogen 2.780 N/A TYR 77.A OH PRO 219.A O no hydrogen 2.801 N/A VAL 78.A N CYS 131.A O no hydrogen 3.183 N/A SER 79.A N GLU 60.A O no hydrogen 2.757 N/A SER 79.A OG GLU 60.A OE1 no hydrogen 2.724 N/A LYS 80.A N GLU 60.A O no hydrogen 3.223 N/A LYS 80.A NZ ASP 220.A OD2 no hydrogen 2.736 N/A CYS 81.A SG GLY 58.A O no hydrogen 3.881 N/A ASP 82.A N GLY 58.A O no hydrogen 3.070 N/A THR 83.A N ASP 82.A OD1 no hydrogen 2.844 N/A THR 83.A OG1 ASN 152.A OD1 no hydrogen 3.379 N/A VAL 84.A N VAL 56.A O.A no hydrogen 2.941 N/A VAL 84.A N VAL 56.A O.B no hydrogen 3.378 N/A THR 90.A OG1 SER 89.A O no hydrogen 2.327 N/A LYS 95.A N LYS 92.A O no hydrogen 2.837 N/A VAL 96.A N TRP 93.A O no hydrogen 3.111 N/A ILE 97.A N TRP 93.A O no hydrogen 2.887 N/A GLY 98.A N GLY 94.A O no hydrogen 3.038 N/A VAL 100.A N VAL 96.A O no hydrogen 3.123 N/A LEU 101.A N ILE 97.A O no hydrogen 2.780 N/A GLN 102.A N GLY 98.A O no hydrogen 2.882 N/A GLN 102.A NE2 ILE 170.A O no hydrogen 3.615 N/A TYR 103.A N PRO 99.A O no hydrogen 2.933 N/A TYR 103.A OH ASP 276.A OD2 no hydrogen 2.370 N/A ILE 104.A N VAL 100.A O no hydrogen 2.977 N/A ILE 105.A N LEU 101.A O no hydrogen 2.875 N/A ASN 106.A N GLN 102.A O no hydrogen 3.081 N/A ASN 106.A ND2 GLN 102.A O no hydrogen 3.010 N/A TYR 107.A N ILE 104.A O no hydrogen 3.448 N/A TYR 107.A OH ASP 276.A O no hydrogen 2.786 N/A ASN 108.A ND2 THR 272.A O no hydrogen 3.320 N/A TYR 110.A OH HIS 45.A NE2 no hydrogen 2.876 N/A LYS 111.A NZ ASP 275.A OD2.B no hydrogen 3.188 N/A LYS 115.A NZ ASP 39.A OD1 no hydrogen 3.356 N/A ARG 120.A N ILE 112.A O no hydrogen 2.596 N/A ARG 120.A NH1 TYR 23.A OH no hydrogen 3.026 N/A ARG 120.A NH1 ASP 39.A OD2 no hydrogen 2.675 N/A ARG 120.A NH2 ASP 39.A OD2 no hydrogen 3.185 N/A THR 125.A OG1 GLU 270.A OE1.B no hydrogen 2.860 N/A THR 125.A OG1 GLU 270.A OE2.B no hydrogen 3.064 N/A GLN 126.A N LEU 269.A O no hydrogen 2.835 N/A GLN 126.A NE2 ASN 108.A OD1 no hydrogen 3.372 N/A GLN 126.A NE2 PRO 123.A O no hydrogen 3.345 N/A ASN 127.A N VAL 72.A O no hydrogen 2.838 N/A ASN 127.A ND2 GLU 73.A OE2 no hydrogen 2.777 N/A LEU 128.A N LYS 266.A O no hydrogen 2.804 N/A ARG 129.A N LYS 74.A O no hydrogen 2.733 N/A ARG 129.A NE GLU 73.A OE1 no hydrogen 2.918 N/A ARG 129.A NH1 LEU 128.A O no hydrogen 2.860 N/A ARG 129.A NH1 GLU 267.A OE1 no hydrogen 3.415 N/A ARG 129.A NH1 GLU 267.A OE2 no hydrogen 2.924 N/A ARG 129.A NH2 GLU 73.A OE1 no hydrogen 3.147 N/A ARG 129.A NH2 GLU 267.A OE1 no hydrogen 3.025 N/A ARG 129.A NH2 GLU 267.A OE2 no hydrogen 3.390 N/A LEU 130.A N CYS 264.A O no hydrogen 2.800 N/A CYS 131.A N VAL 76.A O no hydrogen 2.844 N/A VAL 132.A N ILE 262.A O no hydrogen 2.894 N/A THR 134.A N SER 260.A O no hydrogen 2.942 N/A LYS 135.A NZ GLU 252.A OE2 no hydrogen 2.876 N/A ALA 137.A N LYS 135.A O no hydrogen 2.707 N/A TYR 140.A OH.A LYS 135.A O no hydrogen 2.692 N/A TYR 140.A OH.B LYS 135.A O no hydrogen 2.911 N/A LEU 141.A N ASP 82.A OD2 no hydrogen 3.011 N/A PHE 142.A N ASP 82.A OD2 no hydrogen 3.118 N/A ASN 144.A N GLU 139.A OE1 no hydrogen 2.834 N/A ASN 144.A ND2 ASP 297.A OD1 no hydrogen 3.023 N/A ASN 144.A ND2 SER 299.A OG no hydrogen 3.247 N/A SER 145.A N PHE 142.A O no hydrogen 3.270 N/A SER 145.A OG PHE 142.A O no hydrogen 2.578 N/A ALA 146.A N GLU 139.A OE2 no hydrogen 3.067 N/A ASN 148.A N SER 145.A O no hydrogen 2.991 N/A ASN 148.A ND2 VAL 84.A O no hydrogen 2.730 N/A ASN 148.A ND2 PHE 298.A O no hydrogen 2.913 N/A TYR 150.A N GLY 85.A O no hydrogen 3.154 N/A LYS 151.A NZ ASP 82.A OD1 no hydrogen 2.909 N/A LYS 151.A NZ ASP 82.A OD2 no hydrogen 3.519 N/A LYS 151.A NZ THR 83.A O no hydrogen 3.150 N/A LYS 151.A NZ LYS 138.A O no hydrogen 2.843 N/A LYS 151.A NZ SER 145.A OG no hydrogen 2.653 N/A ASN 152.A N ASN 152.A OD1 no hydrogen 2.465 N/A ASN 155.A N SER 158.A OG.B no hydrogen 3.220 N/A GLY 156.A N ASP 257.A OD2 no hydrogen 2.644 N/A SER 158.A N.A ASN 155.A OD1 no hydrogen 2.764 N/A SER 158.A N.B ASN 155.A OD1 no hydrogen 2.765 N/A SER 158.A OG.A ASN 155.A OD1 no hydrogen 2.847 N/A SER 158.A OG.B ASN 155.A O no hydrogen 3.096 N/A SER 158.A OG.B ASN 155.A OD1 no hydrogen 2.779 N/A LEU 159.A N ASN 155.A O no hydrogen 3.016 N/A LEU 160.A N GLY 156.A O no hydrogen 3.159 N/A ARG 161.A N.A GLN 157.A O.A no hydrogen 3.149 N/A ARG 161.A N.A GLN 157.A O.B no hydrogen 2.990 N/A ARG 161.A N.B GLN 157.A O.A no hydrogen 3.144 N/A ARG 161.A N.B GLN 157.A O.B no hydrogen 2.985 N/A ARG 161.A NH1.A GLN 157.A OE1.A no hydrogen 2.658 N/A ARG 161.A NH1.B GLN 157.A OE1.A no hydrogen 2.755 N/A ARG 161.A NH2.A GLN 157.A OE1.A no hydrogen 3.128 N/A ARG 161.A NH2.A GLN 157.A OE1.B no hydrogen 3.425 N/A TRP 162.A N SER 158.A O.A no hydrogen 2.961 N/A TRP 162.A N SER 158.A O.B no hydrogen 3.031 N/A TRP 163.A N LEU 159.A O no hydrogen 2.999 N/A ILE 164.A N LEU 160.A O no hydrogen 2.887 N/A SER 165.A N ARG 161.A O.A no hydrogen 3.137 N/A SER 165.A N ARG 161.A O.B no hydrogen 3.119 N/A ILE 166.A N.A TRP 162.A O no hydrogen 3.129 N/A ILE 166.A N.B TRP 162.A O no hydrogen 3.129 N/A ILE 167.A N TRP 163.A O no hydrogen 2.841 N/A ASP 168.A N ILE 164.A O no hydrogen 2.916 N/A SER 169.A N SER 165.A O no hydrogen 3.350 N/A SER 169.A N ILE 166.A O.A no hydrogen 3.171 N/A SER 169.A N ILE 166.A O.B no hydrogen 3.100 N/A SER 169.A OG SER 165.A O no hydrogen 3.564 N/A SER 169.A OG ILE 166.A O.A no hydrogen 2.671 N/A SER 169.A OG ILE 166.A O.B no hydrogen 2.644 N/A ILE 170.A N ILE 167.A O no hydrogen 3.256 N/A THR 171.A OG1 ILE 167.A O no hydrogen 2.466 N/A THR 171.A OG1 HIS 177.A NE2 no hydrogen 2.999 N/A TRP 174.A N THR 171.A O no hydrogen 3.159 N/A ASN 175.A N CYS 265.A O no hydrogen 2.692 N/A ASN 176.A N CYS 265.A O no hydrogen 3.365 N/A HIS 177.A NE2 THR 171.A O no hydrogen 2.821 N/A LYS 178.A N GLY 263.A O no hydrogen 2.661 N/A LYS 178.A NZ SER 200.A OG no hydrogen 2.883 N/A LYS 178.A NZ GLU 201.A O no hydrogen 2.988 N/A LEU 179.A N SER 200.A O no hydrogen 2.990 N/A MET 180.A N LEU 261.A O no hydrogen 2.898 N/A ALA 184.A N ILE 181.A O no hydrogen 2.935 N/A ALA 188.A N ASP 185.A OD1 no hydrogen 3.092 N/A THR 189.A N ASP 185.A O no hydrogen 3.152 N/A THR 189.A OG1 ASP 185.A O no hydrogen 3.406 N/A ARG 190.A N LYS 186.A O no hydrogen 2.828 N/A ARG 190.A NE ARG 190.A O no hydrogen 3.426 N/A ARG 190.A NH1 TRP 199.A O no hydrogen 3.388 N/A LYS 191.A N TYR 187.A O no hydrogen 3.187 N/A LYS 191.A NZ GLN 157.A OE1.B no hydrogen 3.444 N/A PHE 192.A N THR 189.A O no hydrogen 3.233 N/A ILE 193.A N ARG 190.A O no hydrogen 3.097 N/A TYR 196.A N ILE 193.A O no hydrogen 3.201 N/A TRP 199.A N TYR 196.A O no hydrogen 3.161 N/A TRP 199.A NE1 ASP 168.A OD1 no hydrogen 2.832 N/A SER 200.A N HIS 177.A O no hydrogen 2.851 N/A GLY 202.A N LEU 179.A O no hydrogen 2.941 N/A PHE 205.A N HIS 203.A ND1 no hydrogen 3.119 N/A LYS 207.A NZ HIS 203.A O no hydrogen 2.724 N/A LYS 207.A NZ PHE 205.A O no hydrogen 2.670 N/A ALA 211.A N MET 238.A O no hydrogen 2.873 N/A GLN 213.A N LEU 210.A O no hydrogen 3.224 N/A ALA 214.A N ALA 211.A O no hydrogen 3.075 N/A ILE 215.A N ALA 211.A O no hydrogen 2.930 N/A LEU 217.A N PRO 27.A O no hydrogen 2.959 N/A ARG 224.A N ASP 221.A O no hydrogen 2.772 N/A ARG 224.A NE GLU 252.A OE1 no hydrogen 2.854 N/A ARG 224.A NH1 ASP 220.A OD1 no hydrogen 2.780 N/A ARG 224.A NH2 GLU 252.A OE1 no hydrogen 3.425 N/A ARG 224.A NH2 GLU 252.A OE2 no hydrogen 2.345 N/A GLU 227.A N GLY 223.A O no hydrogen 2.783 N/A LEU 228.A N ARG 224.A O no hydrogen 3.247 N/A VAL 229.A N PHE 225.A O no hydrogen 2.965 N/A ILE 230.A N LEU 226.A O no hydrogen 3.085 N/A VAL 231.A N GLU 227.A O no hydrogen 2.881 N/A GLU 232.A N LEU 228.A O no hydrogen 2.818 N/A CYS 233.A N ILE 230.A O no hydrogen 3.206 N/A CYS 233.A SG VAL 231.A O no hydrogen 4.003 N/A ARG 234.A N VAL 229.A O no hydrogen 2.791 N/A ARG 234.A NH1 GLU 232.A OE1 no hydrogen 2.794 N/A LYS 237.A N ARG 234.A O no hydrogen 3.230 N/A MET 238.A N ARG 234.A O no hydrogen 3.094 N/A THR 239.A OG1 SER 241.A OG no hydrogen 2.748 N/A VAL 240.A N GLY 209.A O no hydrogen 3.050 N/A SER 241.A OG THR 239.A OG1 no hydrogen 2.748 N/A ARG 242.A N THR 239.A OG1 no hydrogen 3.068 N/A ARG 242.A NE GLN 245.A OE1 no hydrogen 2.866 N/A PHE 243.A N THR 239.A O no hydrogen 2.914 N/A TYR 244.A N VAL 240.A O no hydrogen 3.232 N/A GLN 245.A N SER 241.A O no hydrogen 3.057 N/A GLU 246.A N ARG 242.A O no hydrogen 2.912 N/A LEU 247.A N PHE 243.A O no hydrogen 2.757 N/A TYR 249.A N GLU 246.A O no hydrogen 3.099 N/A ARG 250.A N.A LEU 247.A O no hydrogen 3.247 N/A ARG 250.A N.B LEU 247.A O no hydrogen 3.234 N/A PHE 253.A N ARG 250.A O.A no hydrogen 2.915 N/A PHE 253.A N ARG 250.A O.B no hydrogen 3.197 N/A LEU 254.A N ARG 250.A O.A no hydrogen 2.745 N/A LEU 254.A N ARG 250.A O.B no hydrogen 2.726 N/A LEU 255.A N GLN 251.A O no hydrogen 3.035 N/A GLY 256.A N PHE 253.A O no hydrogen 3.066 N/A SER 260.A N THR 134.A O no hydrogen 3.071 N/A SER 260.A OG CYS 258.A O no hydrogen 2.839 N/A LEU 261.A N MET 180.A O no hydrogen 2.749 N/A ILE 262.A N VAL 132.A O no hydrogen 2.643 N/A GLY 263.A N LYS 178.A O no hydrogen 2.954 N/A CYS 264.A N LEU 130.A O no hydrogen 2.939 N/A CYS 265.A N ASN 176.A O no hydrogen 3.240 N/A CYS 265.A N ASN 176.A OD1 no hydrogen 2.812 N/A CYS 265.A SG ASN 176.A OD1 no hydrogen 3.333 N/A LYS 266.A N LEU 128.A O no hydrogen 3.059 N/A LYS 266.A NZ GLY 173.A O no hydrogen 3.470 N/A GLU 267.A N ASN 175.A OD1 no hydrogen 2.811 N/A ASN 268.A N ASN 127.A OD1 no hydrogen 2.673 N/A LEU 269.A N GLN 126.A O no hydrogen 3.009 N/A VAL 271.A N LYS 124.A O no hydrogen 2.702 N/A HIS 274.A N ASN 108.A O no hydrogen 3.106 N/A THR 280.A OG1 ASN 20.A OD1 no hydrogen 3.426 N/A VAL 281.A N GLN 18.A O no hydrogen 2.805 N/A THR 282.A N GLU 285.A OE1 no hydrogen 3.041 N/A GLU 285.A N THR 282.A OG1 no hydrogen 3.109 N/A TYR 286.A N THR 282.A O no hydrogen 2.928 N/A TYR 286.A OH GLU 60.A OE2 no hydrogen 2.728 N/A LYS 287.A N ILE 283.A O.A no hydrogen 2.820 N/A LYS 287.A N ILE 283.A O.B no hydrogen 2.858 N/A GLU 288.A N SER 284.A O no hydrogen 2.822 N/A PHE 289.A N GLU 285.A O no hydrogen 3.050 N/A MET 290.A N TYR 286.A O no hydrogen 2.971 N/A ASN 291.A N LYS 287.A O no hydrogen 2.707 N/A LEU 292.A N GLU 288.A O no hydrogen 3.050 N/A LEU 293.A N PHE 289.A O no hydrogen 2.985 N/A LYS 294.A N MET 290.A O no hydrogen 3.166 N/A LYS 294.A NZ MET 290.A O no hydrogen 3.524 N/A LEU 295.A N LEU 292.A O no hydrogen 3.142 N/A VAL 296.A N LEU 293.A O no hydrogen 3.323 N/A ASP 297.A N GLU 303.A OE1 no hydrogen 2.815 N/A PHE 298.A N PRO 143.A O no hydrogen 3.038 N/A SER 299.A N ASP 297.A OD1 no hydrogen 3.041 N/A SER 299.A OG ASP 297.A OD1 no hydrogen 2.447 N/A SER 299.A OG ASP 297.A OD2 no hydrogen 3.136 N/A ASP 300.A N ASP 297.A O no hydrogen 2.929 N/A VAL 302.A N ASP 300.A OD1 no hydrogen 2.929 N/A VAL 304.A N ASP 300.A O no hydrogen 3.036 N/A SER 305.A N ARG 301.A O no hydrogen 2.891 N/A SER 305.A OG ARG 301.A O no hydrogen 2.778 N/A ASN 306.A N VAL 302.A O no hydrogen 2.903 N/A PHE 307.A N GLU 303.A O no hydrogen 2.979 N/A VAL 308.A N VAL 304.A O no hydrogen 2.974 N/A SER 309.A N SER 305.A O no hydrogen 2.815 N/A ASN 310.A N ASN 306.A O no hydrogen 2.919 N/A TYR 311.A N PHE 307.A O no hydrogen 3.131 N/A ARG 312.A N VAL 308.A O no hydrogen 3.009 N/A ARG 312.A NE GLU 13.A OE2.A no hydrogen 3.235 N/A ARG 312.A NH1 ASP 53.A OD1 no hydrogen 2.885 N/A ARG 312.A NH2 GLU 13.A OE2.A no hydrogen 2.664 N/A ARG 312.A NH2 GLN 52.A O no hydrogen 2.851 N/A LYS 313.A N SER 309.A O no hydrogen 3.080 N/A SER 314.A N TYR 311.A O no hydrogen 2.933 N/A SER 314.A OG ASN 310.A O no hydrogen 2.702 N/A