Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7d5a_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 3.A N ASP 172.A OD2 no hydrogen 2.859 N/A GLU 5.A N GLU 5.A OE2 no hydrogen 2.726 N/A MET 6.A N PHE 3.A O no hydrogen 3.014 N/A VAL 7.A N VAL 4.A O no hydrogen 3.237 N/A ASP 8.A N SER 165.A OG no hydrogen 3.033 N/A ASN 9.A ND2 HIS 93.A O no hydrogen 3.016 N/A ASN 9.A ND2 MET 166.A O no hydrogen 2.974 N/A LEU 10.A N GLY 164.A O no hydrogen 3.035 N/A ARG 11.A N TYR 19.A O no hydrogen 3.077 N/A ARG 11.A NH1 ASP 8.A OD1 no hydrogen 3.318 N/A ARG 11.A NH1 ASP 8.A OD2 no hydrogen 2.690 N/A ARG 11.A NH2 ASP 8.A OD1 no hydrogen 2.744 N/A ARG 11.A NH2 LEU 10.A O no hydrogen 2.781 N/A GLY 12.A N VAL 162.A O no hydrogen 3.179 N/A GLN 16.A N LYS 13.A O no hydrogen 2.857 N/A TYR 18.A OH GLU 319.A OE2 no hydrogen 2.624 N/A TYR 19.A N ARG 11.A O no hydrogen 2.859 N/A VAL 20.A N ILE 33.A O no hydrogen 2.679 N/A MET 22.A N LEU 31.A O no hydrogen 2.845 N/A THR 23.A N SER 90.A O no hydrogen 2.794 N/A VAL 24.A N GLN 29.A O no hydrogen 3.011 N/A GLY 25.A N LEU 88.A O no hydrogen 2.848 N/A SER 26.A N SER 61.A OG no hydrogen 3.135 N/A SER 26.A OG THR 63.A OG1 no hydrogen 2.630 N/A GLN 29.A N VAL 24.A O no hydrogen 2.751 N/A GLN 29.A NE2 GLN 57.A O no hydrogen 2.943 N/A LEU 31.A N MET 22.A O no hydrogen 2.872 N/A ASN 32.A N GLU 120.A OE2 no hydrogen 2.773 N/A ASN 32.A ND2 ASN 118.A O no hydrogen 2.987 N/A ILE 33.A N VAL 20.A O no hydrogen 2.784 N/A LEU 34.A N GLY 121.A O no hydrogen 2.877 N/A VAL 35.A N TYR 18.A O no hydrogen 2.790 N/A ASP 36.A N LEU 123.A O no hydrogen 3.076 N/A THR 37.A N SER 221.A OG no hydrogen 3.005 N/A THR 37.A OG1 VAL 219.A O no hydrogen 2.817 N/A GLY 38.A N ASP 36.A OD2 no hydrogen 3.001 N/A SER 39.A OG ASP 36.A OD1 no hydrogen 2.572 N/A SER 40.A OG TYR 127.A O no hydrogen 2.746 N/A ASN 41.A ND2 ARG 132.A O no hydrogen 3.064 N/A ALA 43.A N ILE 122.A O no hydrogen 3.027 N/A VAL 44.A N ALA 104.A O no hydrogen 2.943 N/A GLY 45.A N GLU 120.A O no hydrogen 2.733 N/A ALA 46.A N ILE 106.A O no hydrogen 2.987 N/A HIS 49.A N ALA 47.A O no hydrogen 2.862 N/A PHE 51.A N HIS 49.A ND1 no hydrogen 3.069 N/A LEU 52.A N HIS 49.A O no hydrogen 3.104 N/A ARG 54.A NE GLU 120.A OE2 no hydrogen 2.742 N/A TYR 56.A N GLY 45.A O no hydrogen 2.767 N/A TYR 56.A OH ASP 87.A OD2 no hydrogen 2.553 N/A GLN 57.A N GLN 29.A OE1 no hydrogen 2.786 N/A ARG 58.A NH1 GLU 83.A OE2 no hydrogen 2.632 N/A ARG 58.A NH2 GLU 83.A OE2 no hydrogen 2.868 N/A GLN 59.A N GLN 59.A OE1 no hydrogen 2.913 N/A GLN 59.A NE2 GLN 57.A OE1 no hydrogen 3.466 N/A LEU 60.A N GLN 57.A O no hydrogen 3.034 N/A SER 61.A N ARG 58.A O no hydrogen 3.114 N/A SER 61.A OG ASP 87.A OD1 no hydrogen 3.272 N/A SER 61.A OG ASP 87.A OD2 no hydrogen 2.674 N/A SER 62.A N SER 26.A O no hydrogen 3.097 N/A SER 62.A OG SER 26.A O no hydrogen 3.347 N/A THR 63.A OG1 SER 26.A OG no hydrogen 2.630 N/A THR 63.A OG1 ASP 87.A OD1 no hydrogen 2.694 N/A ARG 65.A N THR 86.A O no hydrogen 3.002 N/A LEU 67.A N LEU 84.A O no hydrogen 3.047 N/A ARG 68.A N ASP 66.A OD1 no hydrogen 2.730 N/A VAL 71.A N GLY 82.A O no hydrogen 2.995 N/A VAL 73.A N TRP 80.A O no hydrogen 2.882 N/A TYR 75.A N GLY 78.A O no hydrogen 2.965 N/A LYS 79.A N ASP 110.A O no hydrogen 2.901 N/A LYS 79.A NZ GLU 108.A OE2 no hydrogen 3.358 N/A TRP 80.A N VAL 73.A O no hydrogen 2.977 N/A GLU 81.A N GLU 108.A O no hydrogen 2.885 N/A GLY 82.A N VAL 71.A O no hydrogen 2.935 N/A GLU 83.A N ALA 105.A O no hydrogen 2.878 N/A LEU 84.A N LYS 69.A O no hydrogen 2.785 N/A GLY 85.A N ILE 103.A O no hydrogen 2.929 N/A THR 86.A N ARG 65.A O no hydrogen 2.906 N/A ASP 87.A N ALA 101.A O no hydrogen 3.114 N/A LEU 88.A N ASP 87.A OD1 no hydrogen 2.777 N/A VAL 89.A N VAL 99.A O no hydrogen 2.722 N/A SER 90.A N THR 23.A O no hydrogen 2.953 N/A GLY 94.A N ILE 91.A O no hydrogen 2.934 N/A VAL 97.A N PRO 95.A O no hydrogen 2.696 N/A VAL 99.A N VAL 89.A O no hydrogen 3.003 N/A ARG 100.A N GLN 147.A OE1 no hydrogen 2.984 N/A ARG 100.A NH1 THR 63.A O no hydrogen 2.962 N/A ARG 100.A NH1 THR 86.A OG1 no hydrogen 2.756 N/A ARG 100.A NH2 THR 63.A O no hydrogen 2.879 N/A ALA 101.A N ASP 87.A O no hydrogen 2.995 N/A ASN 102.A ND2 GLU 138.A O no hydrogen 2.960 N/A ILE 103.A N GLY 85.A O no hydrogen 2.860 N/A ALA 104.A N PHE 42.A O no hydrogen 2.952 N/A ALA 105.A N GLU 83.A O no hydrogen 2.864 N/A ILE 106.A N VAL 44.A O no hydrogen 2.788 N/A THR 107.A N GLU 81.A O no hydrogen 2.986 N/A GLU 108.A N GLU 81.A O no hydrogen 3.496 N/A ASP 110.A N LYS 79.A O no hydrogen 2.830 N/A SER 117.A N ILE 114.A O no hydrogen 3.226 N/A SER 117.A OG ILE 114.A O no hydrogen 3.151 N/A ASN 118.A ND2 TYR 19.A OH no hydrogen 2.970 N/A TRP 119.A NE1 GLN 16.A O no hydrogen 3.059 N/A GLU 120.A N ASN 32.A O no hydrogen 2.870 N/A ILE 122.A N ALA 43.A O no hydrogen 2.790 N/A LEU 123.A N LEU 34.A O no hydrogen 2.722 N/A GLY 124.A N ASN 41.A O no hydrogen 2.861 N/A LEU 125.A N ASP 36.A O no hydrogen 2.794 N/A ALA 126.A N SER 39.A O no hydrogen 2.856 N/A TYR 127.A N TRP 189.A O no hydrogen 3.007 N/A ILE 130.A N TYR 127.A O no hydrogen 3.173 N/A ALA 131.A N ALA 128.A O no hydrogen 2.956 N/A ARG 132.A N ASN 41.A OD1 no hydrogen 2.912 N/A SER 136.A N ASP 134.A OD1 no hydrogen 3.034 N/A SER 136.A OG ASP 134.A OD1 no hydrogen 2.515 N/A LEU 137.A N ASP 134.A O no hydrogen 3.203 N/A SER 143.A N PRO 139.A O no hydrogen 3.205 N/A SER 143.A OG GLU 138.A OE1 no hydrogen 2.580 N/A SER 143.A OG PRO 139.A O no hydrogen 3.277 N/A LEU 144.A N PHE 140.A O no hydrogen 2.870 N/A VAL 145.A N PHE 141.A O no hydrogen 3.017 N/A LYS 146.A N ASP 142.A O no hydrogen 2.957 N/A GLN 147.A N SER 143.A O no hydrogen 3.062 N/A GLN 147.A NE2 ARG 100.A O no hydrogen 2.895 N/A THR 148.A OG1 LEU 144.A O no hydrogen 2.410 N/A VAL 150.A N THR 148.A OG1 no hydrogen 3.233 N/A LEU 153.A N PRO 151.A O no hydrogen 2.885 N/A PHE 154.A N PHE 325.A O no hydrogen 3.292 N/A SER 155.A N ILE 167.A O no hydrogen 2.903 N/A SER 155.A OG GLY 170.A O no hydrogen 2.824 N/A SER 155.A OG TYR 322.A OH no hydrogen 2.613 N/A LEU 156.A N VAL 323.A O no hydrogen 2.823 N/A GLN 157.A N SER 165.A O no hydrogen 2.943 N/A GLN 157.A NE2 LEU 175.A O no hydrogen 2.984 N/A CYS 159.A N GLY 163.A O no hydrogen 2.859 N/A CYS 159.A SG GLN 157.A OE1 no hydrogen 3.438 N/A VAL 162.A N GLY 12.A O no hydrogen 2.973 N/A SER 165.A N GLN 157.A O no hydrogen 2.866 N/A MET 166.A N ASN 9.A OD1 no hydrogen 2.766 N/A ILE 167.A N SER 155.A O no hydrogen 2.907 N/A GLY 169.A N LEU 153.A O no hydrogen 2.748 N/A ASP 172.A N TYR 322.A OH no hydrogen 2.962 N/A HIS 173.A N GLY 1.A O no hydrogen 3.301 N/A HIS 173.A ND1 TYR 176.A OH no hydrogen 2.862 N/A SER 174.A N ASP 172.A OD1 no hydrogen 3.124 N/A SER 174.A OG ASP 172.A OD1 no hydrogen 2.720 N/A LEU 175.A N ASP 172.A O no hydrogen 2.906 N/A TYR 176.A OH HIS 173.A ND1 no hydrogen 2.862 N/A THR 177.A N VAL 336.A O no hydrogen 3.059 N/A SER 179.A OG LEU 180.A O no hydrogen 2.999 N/A TRP 181.A N PHE 334.A O no hydrogen 2.838 N/A THR 183.A N ILE 332.A O no hydrogen 2.798 N/A THR 183.A OG1 MET 275.A O no hydrogen 2.680 N/A ILE 185.A N LYS 330.A O no hydrogen 2.788 N/A ARG 186.A N GLU 192.A O no hydrogen 2.803 N/A ARG 186.A NH1 GLU 192.A OE2 no hydrogen 3.082 N/A ARG 186.A NH1 TYR 364.A O no hydrogen 2.856 N/A ARG 186.A NH2 TYR 364.A O no hydrogen 3.026 N/A ARG 187.A NH1 GLU 129.A OE2 no hydrogen 2.776 N/A TRP 189.A N ARG 187.A O no hydrogen 3.090 N/A TRP 189.A N TYR 190.A O no hydrogen 3.174 N/A TRP 189.A NE1 GLU 192.A OE1 no hydrogen 2.935 N/A TYR 191.A OH LEU 125.A O no hydrogen 2.716 N/A VAL 193.A N SER 217.A O no hydrogen 2.961 N/A ILE 195.A N ASN 213.A OD1 no hydrogen 2.778 N/A VAL 196.A N TYR 273.A O no hydrogen 2.831 N/A ARG 197.A NE GLU 199.A OE2 no hydrogen 2.827 N/A ARG 197.A NH2 GLU 199.A OE2 no hydrogen 2.881 N/A GLU 199.A N SER 271.A O no hydrogen 2.954 N/A ILE 200.A N GLN 203.A O no hydrogen 3.002 N/A ASN 201.A N VAL 269.A O no hydrogen 2.960 N/A GLN 203.A N ILE 200.A O no hydrogen 2.835 N/A LEU 205.A N VAL 198.A O no hydrogen 3.038 N/A LYS 206.A N ASP 204.A OD1 no hydrogen 3.071 N/A LYS 210.A N ASP 208.A OD1 no hydrogen 3.165 N/A GLU 211.A N ASP 208.A O no hydrogen 3.067 N/A TYR 212.A N CYS 209.A O no hydrogen 3.208 N/A ASN 213.A N LYS 210.A O no hydrogen 3.245 N/A ASN 213.A ND2 ILE 195.A O no hydrogen 2.719 N/A ASN 213.A ND2 CYS 209.A O no hydrogen 3.097 N/A ASN 213.A ND2 CYS 362.A O no hydrogen 2.982 N/A TYR 214.A N GLU 211.A O no hydrogen 3.255 N/A LYS 216.A NZ THR 309.A O no hydrogen 2.671 N/A SER 217.A OG ASN 213.A OD1 no hydrogen 2.696 N/A ILE 218.A N THR 311.A O no hydrogen 3.017 N/A VAL 219.A N TYR 191.A O no hydrogen 3.035 N/A ASP 220.A N MET 313.A O no hydrogen 2.808 N/A SER 221.A N THR 37.A OG1 no hydrogen 3.007 N/A SER 221.A OG VAL 35.A O no hydrogen 2.763 N/A GLY 222.A N ASP 220.A OD1 no hydrogen 2.807 N/A THR 223.A N ASP 220.A O no hydrogen 3.364 N/A THR 223.A OG1 ASP 220.A OD2 no hydrogen 2.712 N/A ASN 225.A ND2 SER 305.A OG no hydrogen 3.189 N/A LEU 226.A N ALA 303.A O no hydrogen 3.021 N/A ARG 227.A N VAL 312.A O no hydrogen 2.964 N/A LEU 228.A N SER 305.A O no hydrogen 2.853 N/A LYS 230.A NZ GLN 306.A OE1 no hydrogen 2.930 N/A PHE 233.A N PRO 229.A O no hydrogen 2.738 N/A GLU 234.A N LYS 230.A O no hydrogen 2.871 N/A ALA 235.A N LYS 231.A O no hydrogen 3.194 N/A ALA 236.A N VAL 232.A O no hydrogen 2.722 N/A VAL 237.A N PHE 233.A O no hydrogen 2.799 N/A LYS 238.A N GLU 234.A O no hydrogen 3.102 N/A SER 239.A N ALA 235.A O no hydrogen 3.137 N/A ILE 240.A N ALA 236.A O no hydrogen 2.876 N/A LYS 241.A N VAL 237.A O no hydrogen 2.628 N/A ALA 242.A N LYS 238.A O no hydrogen 3.070 N/A ALA 243.A N SER 239.A O no hydrogen 2.953 N/A SER 244.A N ILE 240.A O no hydrogen 3.050 N/A SER 244.A OG ILE 240.A O no hydrogen 2.796 N/A SER 244.A OG LYS 241.A O no hydrogen 3.455 N/A SER 245.A N ALA 242.A O no hydrogen 3.454 N/A SER 245.A OG ALA 242.A O no hydrogen 3.344 N/A PHE 253.A N PRO 250.A O no hydrogen 3.204 N/A LEU 255.A N GLY 252.A O no hydrogen 3.007 N/A GLY 256.A N PHE 253.A O no hydrogen 2.966 N/A GLU 257.A N GLY 252.A O no hydrogen 2.886 N/A VAL 260.A N TYR 300.A O no hydrogen 3.212 N/A TRP 262.A N ASP 298.A O no hydrogen 2.818 N/A ILE 266.A N PRO 263.A O no hydrogen 3.260 N/A PHE 267.A N TRP 264.A O no hydrogen 2.945 N/A VAL 269.A N ASN 201.A OD1 no hydrogen 3.077 N/A ILE 270.A N ILE 287.A O no hydrogen 2.915 N/A SER 271.A N GLU 199.A O no hydrogen 2.813 N/A SER 271.A OG THR 286.A OG1 no hydrogen 2.718 N/A LEU 272.A N ILE 285.A O no hydrogen 2.895 N/A TYR 273.A N ARG 197.A O no hydrogen 2.829 N/A TYR 273.A OH GLU 199.A OE1 no hydrogen 3.279 N/A TYR 273.A OH GLU 199.A OE2 no hydrogen 2.860 N/A LEU 274.A N PHE 283.A O no hydrogen 2.807 N/A MET 275.A N ILE 194.A O no hydrogen 3.134 N/A GLY 276.A N GLN 281.A O no hydrogen 2.828 N/A VAL 278.A N GLN 281.A OE1 no hydrogen 2.968 N/A GLN 281.A N VAL 278.A O no hydrogen 3.008 N/A SER 282.A N PHE 354.A O no hydrogen 2.801 N/A SER 282.A OG THR 356.A OG1 no hydrogen 2.801 N/A PHE 283.A N LEU 274.A O no hydrogen 3.194 N/A ARG 284.A N GLU 351.A O no hydrogen 2.816 N/A ARG 284.A NH1 TYR 273.A OH no hydrogen 3.157 N/A ARG 284.A NH2 GLU 351.A OE1 no hydrogen 2.718 N/A ILE 285.A N LEU 272.A O no hydrogen 2.774 N/A THR 286.A N ALA 349.A O no hydrogen 2.843 N/A THR 286.A OG1 SER 271.A OG no hydrogen 2.718 N/A ILE 287.A N ILE 270.A O no hydrogen 2.794 N/A LEU 288.A N GLN 291.A OE1 no hydrogen 2.924 N/A GLN 290.A N GLN 290.A OE1 no hydrogen 2.821 N/A GLN 290.A NE2 ASP 343.A OD2 no hydrogen 2.932 N/A GLN 291.A N LEU 288.A O no hydrogen 3.067 N/A GLN 291.A NE2 VAL 341.A O no hydrogen 3.064 N/A TYR 292.A OH PRO 268.A O no hydrogen 2.672 N/A LEU 293.A N PRO 289.A O no hydrogen 2.670 N/A ARG 294.A N LYS 301.A O no hydrogen 2.745 N/A ARG 294.A NH1 GLN 291.A O no hydrogen 3.277 N/A ARG 294.A NH1 GLU 319.A OE1 no hydrogen 2.853 N/A ARG 294.A NH2 GLU 319.A OE1 no hydrogen 3.363 N/A ARG 294.A NH2 GLU 319.A OE2 no hydrogen 3.154 N/A VAL 296.A N CYS 299.A O no hydrogen 3.059 N/A TYR 300.A N VAL 260.A O no hydrogen 2.812 N/A LYS 301.A N ARG 294.A O no hydrogen 2.767 N/A ALA 303.A N TYR 292.A O no hydrogen 2.767 N/A SER 305.A N LEU 226.A O no hydrogen 3.049 N/A SER 307.A OG THR 309.A OG1 no hydrogen 3.331 N/A SER 307.A OG GLY 310.A O no hydrogen 2.851 N/A THR 309.A N SER 307.A OG no hydrogen 2.858 N/A THR 309.A OG1 SER 307.A OG no hydrogen 3.331 N/A THR 311.A N LYS 216.A O no hydrogen 2.795 N/A THR 311.A OG1 TYR 212.A O no hydrogen 2.700 N/A VAL 312.A N ARG 227.A O no hydrogen 2.825 N/A MET 313.A N ILE 218.A O no hydrogen 2.821 N/A ALA 315.A N THR 223.A O no hydrogen 2.807 N/A VAL 316.A N THR 224.A O no hydrogen 3.014 N/A ILE 317.A N GLY 314.A O no hydrogen 2.948 N/A MET 318.A N GLY 314.A O no hydrogen 2.995 N/A GLU 319.A N ALA 315.A O no hydrogen 2.893 N/A GLY 320.A N ILE 317.A O no hydrogen 3.205 N/A PHE 321.A N MET 318.A O no hydrogen 2.952 N/A TYR 322.A N ALA 335.A O no hydrogen 2.753 N/A VAL 323.A N LEU 156.A O no hydrogen 2.920 N/A VAL 324.A N GLY 333.A O no hydrogen 2.792 N/A PHE 325.A N PHE 154.A O no hydrogen 2.818 N/A ASP 326.A N ARG 331.A O no hydrogen 2.845 N/A ARG 327.A NE ASN 152.A OD1 no hydrogen 2.873 N/A ARG 327.A NH1 ASP 142.A OD2 no hydrogen 3.011 N/A ARG 327.A NH2 TYR 191.A OH no hydrogen 3.034 N/A ALA 328.A N ASN 152.A O no hydrogen 2.953 N/A ARG 329.A N ASP 326.A O no hydrogen 3.197 N/A ARG 329.A N ASP 326.A OD1 no hydrogen 3.154 N/A ARG 329.A NE ASP 326.A OD2 no hydrogen 3.237 N/A LYS 330.A N ARG 327.A O no hydrogen 3.053 N/A ARG 331.A N ASP 326.A O no hydrogen 3.128 N/A ARG 331.A NE ASP 326.A OD2 no hydrogen 2.781 N/A ARG 331.A NH1 GLU 277.A OE1 no hydrogen 2.778 N/A ARG 331.A NH2 ASP 326.A OD2 no hydrogen 3.280 N/A ILE 332.A N THR 183.A O no hydrogen 2.769 N/A GLY 333.A N VAL 324.A O no hydrogen 2.761 N/A PHE 334.A N TRP 181.A O no hydrogen 2.729 N/A ALA 335.A N TYR 322.A O no hydrogen 3.056 N/A SER 337.A N GLY 320.A O no hydrogen 3.314 N/A ALA 338.A N LEU 175.A O no hydrogen 2.929 N/A CYS 339.A N SER 337.A OG no hydrogen 3.275 N/A CYS 339.A SG SER 337.A OG no hydrogen 3.258 N/A HIS 340.A N SER 337.A O no hydrogen 3.379 N/A HIS 340.A ND1 SER 337.A O no hydrogen 2.849 N/A HIS 342.A ND1 ASP 343.A O no hydrogen 2.933 N/A PHE 345.A N ASP 343.A OD1 no hydrogen 3.035 N/A ARG 346.A N ASP 343.A OD1 no hydrogen 2.800 N/A ARG 346.A NH1 PHE 267.A O no hydrogen 2.789 N/A ARG 346.A NH2 TRP 264.A O no hydrogen 3.056 N/A ARG 346.A NH2 PHE 267.A O no hydrogen 2.836 N/A THR 347.A OG1 ALA 348.A O no hydrogen 3.486 N/A ALA 348.A N HIS 340.A NE2 no hydrogen 3.129 N/A ALA 349.A N THR 286.A O no hydrogen 3.233 N/A GLU 351.A N ARG 284.A O no hydrogen 2.980 N/A PHE 354.A N SER 282.A O no hydrogen 2.775 N/A THR 356.A N ASN 280.A O no hydrogen 2.936 N/A THR 356.A OG1 SER 282.A OG no hydrogen 2.801 N/A ASP 361.A N ASP 358.A O no hydrogen 3.061 N/A CYS 362.A N MET 359.A O no hydrogen 3.101 N/A CYS 362.A SG ASP 358.A O no hydrogen 3.915 N/A