Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7dgq_4.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N SER 58.A OG no hydrogen 2.907 N/A TYR 4.A N MET 1.A O no hydrogen 2.583 N/A TYR 4.A OH THR 37.A O no hydrogen 2.800 N/A ILE 5.A N MET 1.A O no hydrogen 3.361 N/A ILE 6.A N LEU 2.A O no hydrogen 3.248 N/A THR 8.A N TYR 4.A O no hydrogen 3.024 N/A ILE 9.A N ILE 5.A O no hydrogen 2.745 N/A MET 10.A N ILE 6.A O no hydrogen 2.641 N/A LEU 11.A N PRO 7.A O no hydrogen 2.585 N/A MET 12.A N ILE 9.A O no hydrogen 2.802 N/A LEU 14.A N LEU 11.A O no hydrogen 2.537 N/A THR 15.A OG1 MET 12.A O no hydrogen 2.926 N/A TRP 16.A N THR 15.A OG1 no hydrogen 2.454 N/A SER 18.A N THR 15.A O no hydrogen 2.929 N/A SER 18.A OG LEU 14.A O no hydrogen 2.886 N/A ASN 26.A N MET 22.A O no hydrogen 2.885 N/A SER 27.A N ILE 23.A O no hydrogen 3.243 N/A SER 27.A OG ILE 23.A O no hydrogen 3.511 N/A SER 27.A OG TRP 24.A O no hydrogen 3.361 N/A THR 28.A N TRP 24.A O no hydrogen 3.032 N/A THR 28.A OG1 TRP 24.A O no hydrogen 3.032 N/A THR 28.A OG1 VAL 25.A O no hydrogen 3.095 N/A ALA 29.A N VAL 25.A O no hydrogen 3.081 N/A SER 31.A N SER 27.A O no hydrogen 2.824 N/A SER 31.A OG SER 27.A O no hydrogen 2.613 N/A SER 35.A N LEU 32.A O no hydrogen 2.912 N/A SER 35.A OG LEU 32.A O no hydrogen 3.247 N/A PHE 36.A N LEU 33.A O no hydrogen 2.748 N/A THR 37.A OG1 ILE 34.A O no hydrogen 2.144 N/A SER 38.A N ILE 34.A O no hydrogen 2.715 N/A SER 38.A OG SER 35.A O no hydrogen 2.124 N/A LEU 39.A N SER 35.A O no hydrogen 3.310 N/A LEU 40.A N THR 37.A O no hydrogen 2.921 N/A SER 53.A OG PHE 52.A O no hydrogen 2.586 N/A SER 62.A OG SER 62.A O no hydrogen 2.429 N/A THR 63.A OG1 ASP 59.A OD1 no hydrogen 2.592 N/A THR 63.A OG1 THR 63.A O no hydrogen 2.564 N/A LEU 66.A N PRO 64.A O no hydrogen 2.127 N/A THR 69.A OG1 LEU 66.A O no hydrogen 2.275 N/A MET 70.A N LEU 66.A O no hydrogen 3.305 N/A MET 70.A N ILE 67.A O no hydrogen 3.214 N/A TRP 71.A N ILE 67.A O no hydrogen 3.015 N/A LEU 72.A N LEU 68.A O no hydrogen 3.153 N/A LEU 75.A N LEU 72.A O no hydrogen 3.268 N/A MET 76.A N LEU 73.A O no hydrogen 2.856 N/A ALA 79.A N LEU 75.A O no hydrogen 3.196 N/A SER 80.A N MET 76.A O no hydrogen 2.266 N/A SER 80.A OG MET 76.A O no hydrogen 2.905 N/A SER 85.A OG HIS 82.A O no hydrogen 3.268 N/A LYS 86.A N HIS 83.A O no hydrogen 3.425 N/A LYS 92.A N ASN 88.A O no hydrogen 2.825 N/A LYS 93.A N LEU 89.A O no hydrogen 2.543 N/A PHE 95.A N ARG 91.A O no hydrogen 3.140 N/A THR 97.A N LYS 93.A O no hydrogen 3.256 N/A THR 97.A OG1 LYS 93.A O no hydrogen 3.482 N/A THR 97.A OG1 LEU 94.A O no hydrogen 2.170 N/A MET 98.A N LEU 94.A O no hydrogen 2.958 N/A ILE 100.A N ILE 96.A O no hydrogen 3.161 N/A SER 101.A N THR 97.A O no hydrogen 2.642 N/A LEU 102.A N MET 98.A O no hydrogen 2.810 N/A GLN 103.A N LEU 99.A O no hydrogen 3.362 N/A LEU 104.A N ILE 100.A O no hydrogen 2.944 N/A PHE 105.A N LEU 102.A O no hydrogen 2.877 N/A LEU 106.A N LEU 102.A O no hydrogen 3.413 N/A MET 108.A N LEU 104.A O no hydrogen 3.351 N/A THR 109.A N PHE 105.A O no hydrogen 2.595 N/A THR 109.A OG1 PHE 105.A O no hydrogen 3.566 N/A THR 109.A OG1 LEU 121.A O no hydrogen 3.514 N/A THR 111.A N MET 108.A O no hydrogen 3.379 N/A THR 111.A OG1 SER 58.A O no hydrogen 2.158 N/A MET 113.A N THR 111.A O no hydrogen 2.352 N/A TYR 119.A N LEU 115.A O no hydrogen 3.126 N/A TYR 119.A OH SER 157.A O no hydrogen 3.039 N/A TYR 119.A OH SER 157.A OG no hydrogen 3.220 N/A LEU 121.A N LEU 117.A O no hydrogen 3.267 N/A PHE 122.A N PHE 118.A O no hydrogen 2.237 N/A GLU 123.A N TYR 119.A O no hydrogen 2.668 N/A ILE 132.A N THR 129.A O no hydrogen 2.839 N/A ILE 133.A N THR 129.A O no hydrogen 3.123 N/A THR 134.A N LEU 130.A O no hydrogen 3.379 N/A THR 134.A OG1 LEU 130.A O no hydrogen 3.055 N/A ASN 138.A N GLU 222.A OE2 no hydrogen 2.549 N/A GLN 139.A N GLU 222.A OE2 no hydrogen 2.083 N/A ASN 144.A N GLU 141.A O no hydrogen 3.204 N/A GLY 146.A N ARG 142.A O no hydrogen 3.096 N/A TYR 148.A N ASN 144.A O no hydrogen 2.978 N/A PHE 149.A N ALA 145.A O no hydrogen 3.102 N/A THR 153.A OG1 PHE 149.A O no hydrogen 3.035 N/A GLY 156.A N TYR 152.A O no hydrogen 3.336 N/A SER 157.A OG TYR 119.A OH no hydrogen 3.220 N/A SER 157.A OG GLU 123.A OE1 no hydrogen 3.540 N/A SER 157.A OG THR 153.A O no hydrogen 2.860 N/A SER 157.A OG LEU 154.A O no hydrogen 3.553 N/A VAL 162.A N LEU 158.A O no hydrogen 3.111 N/A ALA 163.A N PRO 159.A O no hydrogen 3.101 N/A LEU 164.A N LEU 160.A O no hydrogen 2.675 N/A TYR 166.A N ALA 163.A O no hydrogen 2.649 N/A ILE 167.A N ALA 163.A O no hydrogen 2.946 N/A GLN 168.A N LEU 164.A O no hydrogen 3.224 N/A THR 170.A N ILE 167.A O no hydrogen 2.818 N/A THR 170.A OG1 TYR 166.A O no hydrogen 2.367 N/A VAL 171.A N ILE 167.A O no hydrogen 3.225 N/A LEU 177.A N MET 113.A O no hydrogen 3.185 N/A GLN 180.A NE2 PHE 176.A O no hydrogen 3.199 N/A SER 189.A OG ASN 188.A O no hydrogen 2.306 N/A MET 195.A N SER 191.A O no hydrogen 3.244 N/A TRP 196.A N ASN 192.A O no hydrogen 2.785 N/A LEU 197.A N VAL 193.A O no hydrogen 2.437 N/A ALA 198.A N PHE 194.A O no hydrogen 2.397 N/A ALA 198.A N MET 195.A O no hydrogen 3.046 N/A CYS 199.A N MET 195.A O no hydrogen 2.915 N/A CYS 199.A SG CYS 199.A O no hydrogen 3.032 N/A MET 201.A N LEU 197.A O no hydrogen 3.263 N/A PHE 203.A N MET 200.A O no hydrogen 2.649 N/A VAL 205.A N MET 201.A O no hydrogen 3.367 N/A LYS 206.A N PHE 203.A O no hydrogen 2.992 N/A MET 207.A N PHE 203.A O no hydrogen 3.393 N/A TRP 215.A NE1 VAL 205.A O no hydrogen 3.172 N/A LEU 216.A N HIS 213.A O no hydrogen 2.682 N/A LYS 218.A NZ LEU 214.A O no hydrogen 3.351 N/A ALA 219.A N TRP 215.A O no hydrogen 3.204 N/A HIS 220.A N LEU 216.A O no hydrogen 3.343 N/A VAL 221.A N PRO 217.A O no hydrogen 3.064 N/A GLY 227.A N PRO 224.A O no hydrogen 3.088 N/A LEU 231.A N GLY 227.A O no hydrogen 2.692 N/A ALA 233.A N MET 229.A O no hydrogen 2.906 N/A VAL 234.A N LEU 231.A O no hydrogen 3.212 N/A LEU 235.A N ALA 232.A O no hydrogen 2.860 N/A LEU 236.A N ALA 232.A O no hydrogen 2.890 N/A GLY 239.A N LEU 236.A O no hydrogen 2.959 N/A GLY 240.A N LYS 237.A O no hydrogen 3.013 N/A MET 243.A N GLY 240.A O no hydrogen 3.403 N/A LEU 244.A N TYR 241.A O no hydrogen 2.236 N/A ARG 245.A N GLY 242.A O no hydrogen 2.534 N/A ILE 246.A N GLY 242.A O no hydrogen 3.090 N/A THR 247.A N MET 243.A O no hydrogen 2.969 N/A ILE 249.A N ILE 246.A O no hydrogen 2.395 N/A THR 254.A OG1 VAL 186.A O no hydrogen 3.422 N/A THR 254.A OG1 ASN 251.A OD1 no hydrogen 2.960 N/A ALA 258.A N ASP 255.A O no hydrogen 2.815 N/A PHE 261.A N ALA 258.A O no hydrogen 2.889 N/A ILE 262.A N ALA 258.A O no hydrogen 3.223 N/A ILE 262.A N TYR 259.A O no hydrogen 2.980 N/A MET 263.A N TYR 259.A O no hydrogen 2.982 N/A SER 265.A OG PHE 261.A O no hydrogen 2.799 N/A SER 265.A OG ILE 262.A O no hydrogen 3.315 N/A LEU 266.A N ILE 262.A O no hydrogen 2.646 N/A MET 269.A N SER 265.A O no hydrogen 3.078 N/A MET 271.A N GLY 268.A O no hydrogen 2.599 N/A THR 272.A N GLY 268.A O no hydrogen 2.814 N/A SER 273.A OG MET 269.A O no hydrogen 3.482 N/A SER 274.A N MET 271.A O no hydrogen 2.580 N/A SER 274.A OG ILE 270.A O no hydrogen 3.245 N/A CYS 276.A N SER 273.A O no hydrogen 3.282 N/A CYS 276.A SG CYS 276.A O no hydrogen 2.979 N/A CYS 276.A SG LEU 285.A O no hydrogen 3.073 N/A GLN 279.A NE2 ILE 275.A O no hydrogen 3.083 N/A LEU 282.A N ARG 340.A O no hydrogen 3.175 N/A SER 284.A N ASP 281.A O no hydrogen 3.081 N/A SER 284.A OG GLN 279.A OE1 no hydrogen 3.151 N/A LEU 285.A N ASP 281.A O no hydrogen 3.088 N/A ILE 286.A N LEU 282.A O no hydrogen 3.219 N/A TYR 288.A N SER 284.A O no hydrogen 3.254 N/A SER 289.A OG ILE 286.A O no hydrogen 2.416 N/A SER 290.A N ILE 286.A O no hydrogen 3.295 N/A SER 290.A OG ALA 287.A O no hydrogen 2.162 N/A SER 292.A N TYR 288.A O no hydrogen 3.436 N/A ALA 295.A N VAL 291.A O no hydrogen 2.595 N/A LEU 296.A N SER 292.A O no hydrogen 3.254 N/A VAL 297.A N MET 294.A O no hydrogen 2.815 N/A ALA 300.A N LEU 296.A O no hydrogen 3.303 N/A ILE 301.A N VAL 297.A O no hydrogen 2.664 N/A THR 305.A OG1 GLN 304.A O no hydrogen 2.152 N/A THR 305.A OG1 THR 305.A O no hydrogen 2.293 N/A THR 305.A OG1 SER 384.A OG no hydrogen 2.917 N/A SER 308.A OG ALA 300.A O no hydrogen 3.379 N/A ALA 312.A N SER 308.A O no hydrogen 2.295 N/A THR 313.A N TYR 309.A O no hydrogen 3.242 N/A THR 313.A OG1 TYR 309.A O no hydrogen 3.224 N/A MET 316.A N ALA 312.A O no hydrogen 3.470 N/A ALA 318.A N LEU 315.A O no hydrogen 2.753 N/A LEU 321.A N ALA 318.A O no hydrogen 3.309 N/A THR 322.A OG1 THR 365.A OG1 no hydrogen 3.029 N/A SER 323.A N HIS 319.A O no hydrogen 2.849 N/A MET 325.A N LEU 321.A O no hydrogen 2.659 N/A LEU 326.A N THR 322.A O no hydrogen 3.202 N/A CYS 328.A N MET 325.A O no hydrogen 2.643 N/A LEU 329.A N MET 325.A O no hydrogen 3.070 N/A ALA 330.A N LEU 326.A O no hydrogen 3.028 N/A SER 332.A N CYS 328.A O no hydrogen 3.353 N/A SER 332.A OG LEU 329.A O no hydrogen 2.584 N/A ASN 333.A N LEU 329.A O no hydrogen 3.176 N/A TYR 334.A N ASN 331.A O no hydrogen 2.851 N/A GLU 335.A N ASN 331.A O no hydrogen 2.983 N/A MET 342.A N THR 280.A O no hydrogen 3.234 N/A LEU 344.A N THR 341.A O no hydrogen 3.111 N/A MET 355.A N LEU 352.A O no hydrogen 2.954 N/A ALA 356.A N PRO 353.A O no hydrogen 3.065 N/A TRP 358.A N MET 355.A O no hydrogen 3.353 N/A TRP 359.A N MET 355.A O no hydrogen 3.439 N/A LEU 360.A N ALA 356.A O no hydrogen 3.277 N/A LEU 361.A N THR 357.A O no hydrogen 3.502 N/A ALA 362.A N TRP 358.A O no hydrogen 3.360 N/A SER 363.A N TRP 359.A O no hydrogen 2.854 N/A LEU 364.A N LEU 360.A O no hydrogen 2.783 N/A THR 365.A N ALA 362.A O no hydrogen 2.952 N/A THR 365.A OG1 THR 322.A OG1 no hydrogen 3.029 N/A THR 365.A OG1 LEU 361.A O no hydrogen 3.523 N/A THR 365.A OG1 ALA 362.A O no hydrogen 2.714 N/A THR 372.A N LEU 369.A O no hydrogen 3.393 N/A THR 372.A OG1 LEU 369.A O no hydrogen 3.156 N/A THR 372.A OG1 ASN 374.A OD1 no hydrogen 3.534 N/A GLY 377.A N ILE 373.A O no hydrogen 2.608 N/A GLY 377.A N ASN 374.A O no hydrogen 2.970 N/A GLU 378.A N ASN 374.A O no hydrogen 2.769 N/A LEU 379.A N LEU 375.A O no hydrogen 2.490 N/A VAL 381.A N GLU 378.A O no hydrogen 2.758 N/A VAL 382.A N GLU 378.A O no hydrogen 3.107 N/A SER 384.A OG THR 305.A O no hydrogen 3.443 N/A SER 384.A OG THR 305.A OG1 no hydrogen 2.917 N/A THR 385.A N VAL 381.A O no hydrogen 2.945 N/A PHE 386.A N VAL 382.A O no hydrogen 2.829 N/A TRP 388.A N SER 384.A O no hydrogen 3.199 N/A THR 392.A N SER 389.A O no hydrogen 3.208 N/A THR 392.A OG1 THR 385.A O no hydrogen 2.646 N/A THR 392.A OG1 SER 389.A O no hydrogen 3.208 N/A ILE 393.A N ASN 390.A O no hydrogen 3.463 N/A ILE 394.A N ILE 391.A O no hydrogen 3.159 N/A VAL 398.A N ILE 394.A O no hydrogen 2.600 N/A ASN 399.A N LEU 395.A O no hydrogen 2.831 N/A VAL 401.A N VAL 398.A O no hydrogen 2.738 N/A ILE 402.A N VAL 398.A O no hydrogen 3.179 N/A THR 403.A N ASN 399.A O no hydrogen 3.301 N/A ALA 404.A N VAL 401.A O no hydrogen 2.839 N/A LEU 405.A N VAL 401.A O no hydrogen 3.396 N/A TYR 406.A N ILE 402.A O no hydrogen 2.838 N/A TYR 406.A OH LEU 285.A O no hydrogen 2.740 N/A SER 407.A N THR 403.A O no hydrogen 3.081 N/A SER 407.A OG THR 403.A O no hydrogen 3.382 N/A LEU 408.A N ALA 404.A O no hydrogen 3.403 N/A TYR 409.A N LEU 405.A O no hydrogen 3.424 N/A MET 410.A N SER 407.A O no hydrogen 2.781 N/A ILE 412.A N LEU 408.A O no hydrogen 2.759 N/A THR 414.A N LEU 411.A O no hydrogen 2.513 N/A THR 414.A OG1 LEU 411.A O no hydrogen 2.575 N/A TYR 421.A N THR 420.A OG1 no hydrogen 2.661 N/A HIS 422.A NE2 LEU 344.A O no hydrogen 3.235 N/A SER 429.A OG PRO 428.A O no hydrogen 2.414 N/A ARG 432.A NH1 MET 78.A O no hydrogen 3.328 N/A ARG 432.A NH2 HIS 82.A ND1 no hydrogen 2.937 N/A GLU 433.A N PHE 430.A O no hydrogen 2.519 N/A ALA 435.A N THR 431.A O no hydrogen 2.406 N/A LEU 436.A N ARG 432.A O no hydrogen 3.124 N/A SER 438.A N ASN 434.A O no hydrogen 3.405 N/A SER 438.A OG ASN 434.A O no hydrogen 3.217 N/A SER 438.A OG ALA 435.A O no hydrogen 2.280 N/A LEU 444.A N HIS 440.A O no hydrogen 2.697 N/A LEU 447.A N LEU 444.A O no hydrogen 3.164 N/A THR 448.A N LEU 445.A O no hydrogen 2.881 N/A THR 448.A OG1 LEU 445.A O no hydrogen 2.652 N/A LEU 449.A N LEU 446.A O no hydrogen 2.987 N/A LYS 452.A N ASN 450.A OD1 no hydrogen 3.328 N/A