Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7dy2_H.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N LEU 19.A O no hydrogen 2.860 N/A THR 6.A N ASP 12.A OD1 no hydrogen 2.894 N/A THR 6.A OG1 ASP 12.A OD1 no hydrogen 2.780 N/A MET 7.A N ASP 12.A OD2 no hydrogen 2.959 N/A ILE 8.A N THR 6.A OG1 no hydrogen 3.209 N/A PHE 11.A N ILE 8.A O no hydrogen 2.915 N/A ILE 14.A N GLY 10.A O no hydrogen 3.146 N/A SER 15.A N PHE 11.A O no hydrogen 2.843 N/A SER 15.A OG PHE 11.A O no hydrogen 2.536 N/A SER 15.A OG GLY 18.A O no hydrogen 3.151 N/A HIS 16.A N ASP 13.A O no hydrogen 3.416 N/A GLY 17.A N ASP 12.A O no hydrogen 3.005 N/A GLY 18.A N SER 15.A O no hydrogen 3.168 N/A LEU 19.A N MET 4.A O no hydrogen 2.921 N/A ILE 21.A N ALA 2.A O no hydrogen 2.806 N/A GLY 22.A N THR 144.A OG1 no hydrogen 3.419 N/A ARG 23.A N PRO 20.A O no hydrogen 3.433 N/A THR 25.A N THR 145.A O no hydrogen 3.069 N/A LEU 26.A N ASN 170.A O no hydrogen 3.230 N/A VAL 27.A N MET 147.A O no hydrogen 2.616 N/A SER 28.A N VAL 172.A O no hydrogen 3.269 N/A SER 28.A OG ILE 158.A O no hydrogen 2.392 N/A GLY 29.A N THR 149.A O no hydrogen 3.188 N/A THR 30.A OG1 GLU 154.A OE1 no hydrogen 2.833 N/A THR 30.A OG1 GLU 154.A OE2 no hydrogen 3.231 N/A THR 33.A N THR 30.A O no hydrogen 3.353 N/A THR 33.A OG1 THR 30.A O no hydrogen 2.513 N/A LYS 35.A NZ GLY 29.A O no hydrogen 3.335 N/A PHE 38.A N GLY 34.A O no hydrogen 3.262 N/A SER 39.A N LYS 35.A O no hydrogen 2.937 N/A SER 39.A OG LYS 35.A O no hydrogen 3.052 N/A SER 39.A OG THR 36.A O no hydrogen 2.517 N/A ILE 40.A N THR 36.A O no hydrogen 3.050 N/A GLN 41.A N LEU 37.A O no hydrogen 2.809 N/A PHE 42.A N PHE 38.A O no hydrogen 2.910 N/A LEU 43.A N SER 39.A O no hydrogen 3.285 N/A TYR 44.A N ILE 40.A O no hydrogen 2.956 N/A ASN 45.A N GLN 41.A O no hydrogen 2.799 N/A ASN 45.A ND2 THR 6.A O no hydrogen 3.162 N/A GLY 46.A N PHE 42.A O no hydrogen 3.360 N/A ILE 48.A N TYR 44.A O no hydrogen 3.224 N/A GLU 52.A N GLY 46.A O no hydrogen 2.966 N/A GLY 54.A N LYS 85.A O no hydrogen 3.341 N/A VAL 55.A N ARG 114.A O no hydrogen 2.979 N/A PHE 56.A N PHE 87.A O no hydrogen 2.766 N/A VAL 57.A N SER 116.A O no hydrogen 2.601 N/A THR 58.A N LEU 89.A O no hydrogen 3.515 N/A THR 58.A OG1 GLU 61.A O no hydrogen 2.705 N/A ASP 65.A N THR 62.A O no hydrogen 2.774 N/A ILE 66.A N THR 62.A O no hydrogen 3.041 N/A ILE 67.A N PRO 63.A O no hydrogen 3.287 N/A LYS 68.A N GLN 64.A O no hydrogen 3.189 N/A ASN 69.A N ASP 65.A O no hydrogen 2.920 N/A ALA 70.A N ILE 66.A O no hydrogen 3.245 N/A ARG 71.A N LYS 68.A O no hydrogen 3.286 N/A SER 72.A N ASN 69.A O no hydrogen 3.316 N/A PHE 73.A N ALA 70.A O no hydrogen 3.420 N/A TRP 75.A N ALA 70.A O no hydrogen 2.912 N/A VAL 81.A N LEU 77.A O no hydrogen 2.832 N/A ASP 82.A N ALA 78.A O no hydrogen 2.813 N/A GLU 83.A N LYS 79.A O no hydrogen 2.916 N/A GLY 84.A N VAL 81.A O no hydrogen 2.931 N/A LYS 85.A N LEU 80.A O no hydrogen 2.970 N/A LEU 89.A N PHE 56.A O no hydrogen 2.522 N/A ALA 91.A N THR 58.A O no hydrogen 3.140 N/A SER 92.A N ASP 90.A OD1 no hydrogen 3.220 N/A SER 92.A OG ASP 90.A OD1 no hydrogen 2.501 N/A LEU 99.A N ASP 95.A O no hydrogen 2.659 N/A ILE 100.A N LEU 96.A O no hydrogen 2.576 N/A GLU 101.A N SER 97.A O no hydrogen 3.130 N/A ARG 102.A N ALA 98.A O no hydrogen 2.657 N/A ILE 103.A N LEU 99.A O no hydrogen 3.009 N/A ASN 104.A N GLU 101.A O no hydrogen 3.323 N/A GLN 108.A N TYR 105.A O no hydrogen 2.823 N/A LYS 109.A N TYR 105.A O no hydrogen 2.584 N/A ARG 111.A N GLN 108.A O no hydrogen 3.462 N/A ALA 112.A N ILE 107.A O no hydrogen 2.658 N/A ARG 114.A NE GLU 52.A OE1 no hydrogen 3.116 N/A ARG 114.A NH1 PHE 42.A O no hydrogen 2.502 N/A ARG 114.A NH2 ARG 5.A O no hydrogen 2.559 N/A VAL 115.A N THR 144.A O no hydrogen 3.059 N/A SER 116.A N VAL 55.A O no hydrogen 3.095 N/A SER 116.A OG VAL 115.A O no hydrogen 3.120 N/A ILE 117.A N VAL 146.A O no hydrogen 2.914 N/A ASP 118.A N VAL 57.A O no hydrogen 2.828 N/A SER 119.A OG ASP 118.A O no hydrogen 2.649 N/A SER 119.A OG SER 119.A O no hydrogen 2.512 N/A VAL 120.A N THR 148.A O no hydrogen 3.260 N/A SER 122.A N SER 119.A O no hydrogen 3.143 N/A VAL 123.A N VAL 120.A O no hydrogen 3.212 N/A PHE 124.A N THR 121.A O no hydrogen 3.214 N/A LEU 131.A N VAL 127.A O no hydrogen 2.947 N/A PHE 132.A N ARG 128.A O no hydrogen 2.829 N/A PHE 132.A N ARG 129.A O no hydrogen 3.133 N/A ARG 133.A N GLU 130.A O no hydrogen 3.256 N/A ALA 136.A N PHE 132.A O no hydrogen 3.380 N/A LEU 138.A N LEU 134.A O no hydrogen 2.675 N/A LYS 139.A N VAL 135.A O no hydrogen 2.608 N/A GLN 140.A N ALA 136.A O no hydrogen 2.957 N/A ILE 141.A N ARG 137.A O no hydrogen 3.335 N/A GLY 142.A N LEU 138.A O no hydrogen 3.131 N/A THR 145.A OG1 ALA 143.A O no hydrogen 2.975 N/A VAL 146.A N VAL 115.A O no hydrogen 3.207 N/A MET 147.A N THR 25.A O no hydrogen 2.803 N/A THR 148.A N ILE 117.A O no hydrogen 3.052 N/A THR 149.A N VAL 27.A O no hydrogen 3.203 N/A ARG 151.A NE PRO 157.A O no hydrogen 3.369 N/A ARG 151.A NH2 GLU 154.A O no hydrogen 2.700 N/A TYR 155.A OH GLU 201.A OE1 no hydrogen 3.282 N/A ASN 170.A ND2 THR 25.A OG1 no hydrogen 2.724 N/A VAL 171.A N LYS 191.A O no hydrogen 3.117 N/A VAL 172.A N LEU 26.A O no hydrogen 2.684 N/A ILE 173.A N GLU 188.A O no hydrogen 2.816 N/A LEU 174.A N SER 28.A O no hydrogen 3.161 N/A ARG 175.A NH2 GLU 188.A OE2 no hydrogen 2.524 N/A ASN 176.A N GLU 154.A OE1 no hydrogen 2.912 N/A GLU 179.A N ARG 182.A O no hydrogen 2.593 N/A ARG 183.A NH1 ASN 176.A O no hydrogen 2.401 N/A ARG 184.A N VAL 177.A O no hydrogen 3.049 N/A ARG 184.A NH1 GLN 355.A OE1 no hydrogen 2.497 N/A THR 186.A N ARG 175.A O no hydrogen 3.376 N/A THR 186.A OG1 GLU 201.A OE2 no hydrogen 2.546 N/A LEU 187.A N TYR 202.A O no hydrogen 3.171 N/A GLU 188.A N ILE 173.A O no hydrogen 3.227 N/A LEU 190.A N VAL 171.A O no hydrogen 2.682 N/A ARG 193.A NH1 ASP 169.A OD1 no hydrogen 3.071 N/A THR 195.A OG1 LEU 192.A O no hydrogen 2.823 N/A THR 195.A OG1 ARG 193.A O no hydrogen 2.881 N/A MET 198.A N ILE 14.A O no hydrogen 2.862 N/A LYS 199.A NZ HIS 197.A O no hydrogen 3.183 N/A TYR 202.A N LEU 187.A O no hydrogen 2.848 N/A TYR 202.A OH LYS 199.A O no hydrogen 2.926 N/A PHE 204.A N ARG 185.A O no hydrogen 3.222 N/A THR 205.A N ASN 212.A O no hydrogen 3.356 N/A THR 207.A N GLY 210.A O no hydrogen 2.828 N/A THR 207.A OG1 GLY 210.A O no hydrogen 3.434 N/A HIS 209.A N THR 207.A OG1 no hydrogen 3.265 N/A GLY 210.A N THR 207.A O no hydrogen 3.335 N/A ILE 211.A N GLN 41.A OE1 no hydrogen 2.777 N/A ASN 212.A N THR 205.A O no hydrogen 2.995 N/A ILE 213.A N GLU 9.A O no hydrogen 3.005 N/A PHE 214.A N PRO 203.A O no hydrogen 3.083 N/A SER 220.A N ASP 242.A OD2 no hydrogen 2.799 N/A SER 220.A OG ASP 242.A OD2 no hydrogen 3.289 N/A VAL 222.A N SER 220.A OG no hydrogen 3.279 N/A VAL 224.A N PHE 239.A O no hydrogen 2.553 N/A SER 225.A OG ASP 232.A OD2 no hydrogen 3.049 N/A SER 226.A OG ASP 232.A OD1 no hydrogen 2.444 N/A VAL 228.A N SER 226.A OG no hydrogen 3.400 N/A ASP 232.A N VAL 228.A O no hydrogen 3.024 N/A ASP 232.A N VAL 229.A O no hydrogen 3.075 N/A GLU 233.A N VAL 229.A O no hydrogen 3.224 N/A CYS 235.A N ASP 232.A O no hydrogen 3.037 N/A CYS 235.A SG LEU 231.A O no hydrogen 3.847 N/A GLY 236.A N GLU 233.A O no hydrogen 3.009 N/A GLY 237.A N ASP 232.A O no hydrogen 3.353 N/A LYS 241.A N VAL 222.A O no hydrogen 3.021 N/A SER 243.A OG PHE 240.A O no hydrogen 2.426 N/A ILE 245.A N GLY 371.A O no hydrogen 3.073 N/A LEU 246.A N THR 397.A O no hydrogen 2.727 N/A ALA 247.A N PHE 373.A O no hydrogen 2.649 N/A THR 248.A N ILE 399.A O no hydrogen 2.951 N/A GLY 249.A N ASN 375.A O no hydrogen 3.258 N/A THR 253.A N ALA 250.A O no hydrogen 3.200 N/A THR 253.A OG1 ALA 250.A O no hydrogen 2.382 N/A LYS 255.A NZ GLY 249.A O no hydrogen 3.150 N/A LYS 255.A NZ ALA 250.A O no hydrogen 2.467 N/A THR 256.A OG1 ASP 339.A OD1 no hydrogen 2.280 N/A LEU 258.A N GLY 254.A O no hydrogen 2.839 N/A VAL 259.A N LYS 255.A O no hydrogen 3.176 N/A SER 260.A N THR 256.A O no hydrogen 2.928 N/A SER 260.A OG THR 256.A O no hydrogen 2.984 N/A ARG 261.A N LEU 257.A O no hydrogen 3.495 N/A PHE 262.A N LEU 258.A O no hydrogen 3.185 N/A VAL 263.A N VAL 259.A O no hydrogen 2.994 N/A GLU 264.A N SER 260.A O no hydrogen 2.925 N/A ASN 265.A N ARG 261.A O no hydrogen 2.887 N/A CYS 267.A N VAL 263.A O no hydrogen 3.432 N/A CYS 267.A SG VAL 263.A O no hydrogen 3.013 N/A CYS 267.A SG LEU 304.A O no hydrogen 3.098 N/A ALA 268.A N GLU 264.A O no hydrogen 3.215 N/A ASN 269.A N ASN 265.A O no hydrogen 2.811 N/A GLU 271.A N ALA 266.A O no hydrogen 2.710 N/A ILE 274.A N ARG 335.A O no hydrogen 3.390 N/A LEU 275.A N LYS 306.A O no hydrogen 3.014 N/A PHE 276.A N ALA 337.A O no hydrogen 2.816 N/A ALA 277.A N VAL 308.A O no hydrogen 3.249 N/A TYR 278.A N ASP 339.A O no hydrogen 3.065 N/A LEU 285.A N SER 281.A O no hydrogen 2.825 N/A LEU 286.A N ARG 282.A O no hydrogen 2.803 N/A ARG 287.A N ALA 283.A O no hydrogen 2.746 N/A ARG 287.A N GLN 284.A O no hydrogen 3.155 N/A ARG 287.A NE ASN 288.A OD1 no hydrogen 3.469 N/A ARG 287.A NH2 ASN 288.A OD1 no hydrogen 3.369 N/A ASN 288.A N GLN 284.A O no hydrogen 2.784 N/A TYR 290.A N ARG 287.A O no hydrogen 2.819 N/A SER 291.A N ARG 287.A O no hydrogen 3.437 N/A GLY 293.A N TYR 290.A O no hydrogen 3.078 N/A MET 294.A N ALA 289.A O no hydrogen 2.731 N/A MET 299.A N ASP 295.A O no hydrogen 3.169 N/A GLU 300.A N PHE 296.A O no hydrogen 2.740 N/A ARG 301.A N GLU 297.A O no hydrogen 2.622 N/A GLN 302.A N GLU 298.A O no hydrogen 3.342 N/A ASN 303.A N GLU 300.A O no hydrogen 3.325 N/A LEU 304.A N MET 299.A O no hydrogen 3.427 N/A LYS 306.A N ALA 273.A O no hydrogen 3.203 N/A VAL 308.A N LEU 275.A O no hydrogen 3.310 N/A CYS 309.A SG GLU 280.A O no hydrogen 3.855 N/A ALA 310.A N ALA 277.A O no hydrogen 3.071 N/A SER 314.A N TYR 311.A O no hydrogen 3.218 N/A SER 314.A OG TYR 311.A O no hydrogen 3.420 N/A HIS 320.A N GLY 316.A O no hydrogen 2.608 N/A HIS 320.A NE2 PRO 312.A O no hydrogen 3.157 N/A LEU 321.A N LEU 317.A O no hydrogen 2.707 N/A GLN 322.A N GLU 318.A O no hydrogen 3.035 N/A ILE 323.A N ASP 319.A O no hydrogen 3.056 N/A ILE 324.A N HIS 320.A O no hydrogen 3.262 N/A LYS 325.A N LEU 321.A O no hydrogen 3.048 N/A SER 326.A N GLN 322.A O no hydrogen 3.133 N/A SER 326.A OG ILE 323.A O no hydrogen 2.691 N/A GLU 327.A N ILE 323.A O no hydrogen 2.706 N/A ILE 328.A N ILE 324.A O no hydrogen 2.635 N/A ASN 329.A N LYS 325.A O no hydrogen 2.753 N/A ASN 329.A N SER 326.A O no hydrogen 3.313 N/A ASP 330.A N GLU 327.A O no hydrogen 3.414 N/A PHE 331.A N GLU 327.A O no hydrogen 3.418 N/A ALA 334.A N ARG 272.A O no hydrogen 2.647 N/A ARG 335.A NH1 SER 225.A O no hydrogen 3.171 N/A ARG 335.A NH1 PHE 262.A O no hydrogen 3.203 N/A ARG 335.A NH1 ASN 265.A OD1 no hydrogen 3.547 N/A ILE 336.A N THR 370.A O no hydrogen 3.105 N/A ALA 337.A N ILE 274.A O no hydrogen 3.005 N/A ILE 338.A N LEU 372.A O no hydrogen 3.147 N/A ASP 339.A N PHE 276.A O no hydrogen 3.079 N/A SER 340.A OG GLU 279.A OE2 no hydrogen 2.520 N/A SER 340.A OG SER 342.A OG no hydrogen 2.848 N/A LEU 341.A N THR 374.A O no hydrogen 2.663 N/A SER 342.A OG SER 340.A OG no hydrogen 2.848 N/A LEU 344.A N LEU 341.A O no hydrogen 3.207 N/A ALA 345.A N SER 342.A O no hydrogen 3.195 N/A ASN 350.A ND2 SER 389.A O no hydrogen 3.473 N/A ALA 352.A N SER 349.A OG no hydrogen 3.143 N/A PHE 353.A N SER 349.A O no hydrogen 2.739 N/A ARG 354.A N ASN 350.A O no hydrogen 2.963 N/A GLN 355.A N ASN 351.A O no hydrogen 3.032 N/A PHE 356.A N ALA 352.A O no hydrogen 3.320 N/A VAL 357.A N PHE 353.A O no hydrogen 2.921 N/A ILE 358.A N ARG 354.A O no hydrogen 2.897 N/A GLY 359.A N GLN 355.A O no hydrogen 2.869 N/A VAL 360.A N PHE 356.A O no hydrogen 3.064 N/A THR 361.A N VAL 357.A O no hydrogen 2.954 N/A THR 361.A OG1 VAL 357.A O no hydrogen 2.476 N/A GLY 362.A N ILE 358.A O no hydrogen 2.846 N/A TYR 363.A N GLY 359.A O no hydrogen 3.365 N/A ALA 364.A N VAL 360.A O no hydrogen 3.484 N/A LYS 365.A N THR 361.A O no hydrogen 3.021 N/A GLN 366.A N GLY 362.A O no hydrogen 2.668 N/A GLU 367.A N TYR 363.A O no hydrogen 2.727 N/A GLU 367.A N ALA 364.A O no hydrogen 3.146 N/A GLU 368.A N LYS 365.A O no hydrogen 3.375 N/A ILE 369.A N ALA 364.A O no hydrogen 2.639 N/A LEU 372.A N ILE 336.A O no hydrogen 2.907 N/A PHE 373.A N ILE 245.A O no hydrogen 2.548 N/A THR 374.A N ILE 338.A O no hydrogen 3.031 N/A ASN 375.A N ALA 247.A O no hydrogen 2.977 N/A THR 376.A N SER 342.A OG no hydrogen 3.181 N/A SER 377.A N GLY 249.A O no hydrogen 2.876 N/A SER 377.A OG GLY 249.A O no hydrogen 2.833 N/A SER 385.A OG THR 387.A O no hydrogen 3.447 N/A ILE 391.A N THR 387.A OG1 no hydrogen 3.330 N/A THR 395.A OG1 ILE 244.A O no hydrogen 3.086 N/A THR 395.A OG1 THR 397.A O no hydrogen 2.895 N/A ASP 396.A N ILE 244.A O no hydrogen 2.879 N/A THR 397.A N ILE 244.A O no hydrogen 2.751 N/A ILE 398.A N LYS 418.A O no hydrogen 3.288 N/A ILE 399.A N LEU 246.A O no hydrogen 2.784 N/A LEU 400.A N ASN 415.A O no hydrogen 2.945 N/A LEU 401.A N THR 248.A O no hydrogen 3.199 N/A GLN 402.A N ALA 413.A O no hydrogen 3.067 N/A GLN 402.A NE2 TYR 403.A O no hydrogen 2.640 N/A GLN 402.A NE2 ILE 450.A O no hydrogen 3.388 N/A VAL 404.A N SER 411.A O no hydrogen 2.580 N/A GLU 405.A N GLY 453.A O no hydrogen 2.805 N/A ILE 406.A N GLU 409.A O no hydrogen 2.812 N/A SER 411.A N VAL 404.A O no hydrogen 2.712 N/A SER 411.A OG VAL 404.A O no hydrogen 2.406 N/A ALA 413.A N GLN 402.A O no hydrogen 2.927 N/A ILE 414.A N ARG 429.A O no hydrogen 2.793 N/A ASN 415.A N LEU 400.A O no hydrogen 3.140 N/A PHE 417.A N ILE 398.A O no hydrogen 2.912 N/A LYS 418.A N ILE 398.A O no hydrogen 3.472 N/A LYS 418.A NZ SER 392.A O no hydrogen 3.422 N/A ARG 420.A NH2 THR 393.A O no hydrogen 2.534 N/A SER 422.A OG CYS 235.A O no hydrogen 3.096 N/A SER 422.A OG GLY 236.A O no hydrogen 3.204 N/A SER 422.A OG TRP 423.A O no hydrogen 3.315 N/A ASP 425.A N MET 234.A O no hydrogen 3.128 N/A ARG 429.A N ILE 414.A O no hydrogen 2.907 N/A ARG 429.A NH2 ASP 425.A OD2 no hydrogen 2.564 N/A GLU 430.A N ASP 442.A O no hydrogen 2.951 N/A PHE 431.A N ARG 412.A O no hydrogen 3.241 N/A SER 434.A N GLY 437.A O no hydrogen 3.064 N/A LYS 441.A N GLU 430.A O no hydrogen 2.528 N/A GLU 448.A N THR 456.A O no hydrogen 3.250 N/A SER 452.A OG ARG 449.A O no hydrogen 2.764 N/A SER 452.A OG SER 454.A O no hydrogen 3.412 N/A GLY 453.A N ILE 450.A O no hydrogen 3.243 N/A SER 454.A N SER 452.A OG no hydrogen 3.327 N/A THR 456.A N GLU 448.A O no hydrogen 2.988 N/A ILE 458.A N ASN 446.A O no hydrogen 3.080 N/A