Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7f2z_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 3.A N ASP 158.A OD2 no hydrogen 2.807 N/A ASN 3.A ND2 ASP 158.A OD1 no hydrogen 3.110 N/A MET 4.A N MET 1.A O no hydrogen 3.502 N/A HIS 8.A NE2 HIS 150.A O no hydrogen 2.729 N/A ASN 9.A ND2 ASN 7.A OD1 no hydrogen 3.520 N/A GLN 11.A N GLU 151.A OE1 no hydrogen 2.975 N/A GLN 11.A N GLU 151.A OE2 no hydrogen 3.168 N/A GLN 11.A NE2 ASN 9.A O no hydrogen 3.406 N/A ALA 12.A N GLU 151.A OE2 no hydrogen 3.051 N/A TRP 15.A N HIS 129.A O no hydrogen 2.908 N/A THR 16.A N LYS 145.A O no hydrogen 2.841 N/A THR 16.A OG1 THR 127.A O no hydrogen 2.652 N/A ALA 17.A N THR 127.A OG1 no hydrogen 2.866 N/A GLU 18.A N PRO 143.A O no hydrogen 2.923 N/A GLU 22.A N GLU 22.A OE1 no hydrogen 3.017 N/A MET 23.A N PRO 20.A O no hydrogen 3.136 N/A VAL 26.A N ILE 120.A O no hydrogen 2.909 N/A VAL 27.A N TRP 81.A O no hydrogen 2.977 N/A PHE 28.A N THR 118.A O no hydrogen 2.831 N/A ALA 29.A N ALA 79.A O no hydrogen 2.801 N/A GLN 30.A N GLU 116.A O no hydrogen 3.001 N/A ILE 31.A N PHE 77.A O no hydrogen 2.996 N/A GLY 32.A N TRP 114.A O no hydrogen 2.832 N/A ILE 33.A N SER 75.A O no hydrogen 2.880 N/A GLN 34.A N GLY 112.A O no hydrogen 2.862 N/A GLN 34.A NE2 ASP 74.A OD1 no hydrogen 2.825 N/A GLN 34.A NE2 THR 327.A OG1 no hydrogen 3.068 N/A SER 35.A N GLN 73.A O no hydrogen 2.946 N/A SER 35.A OG SER 37.A O no hydrogen 3.158 N/A HIS 40.A N SER 37.A O no hydrogen 3.136 N/A ALA 41.A N LEU 38.A O no hydrogen 3.055 N/A ALA 42.A N ASP 39.A O no hydrogen 3.169 N/A LEU 45.A N ALA 41.A O no hydrogen 3.000 N/A GLY 46.A N ALA 42.A O no hydrogen 3.133 N/A GLY 46.A N GLU 43.A O no hydrogen 3.120 N/A MET 47.A N GLU 43.A O no hydrogen 3.348 N/A MET 48.A N HIS 44.A O no hydrogen 3.193 N/A LYS 49.A N LEU 45.A O no hydrogen 3.285 N/A LYS 49.A NZ HIS 252.A O no hydrogen 3.451 N/A LYS 50.A N GLY 46.A O no hydrogen 3.237 N/A SER 51.A N MET 47.A O no hydrogen 3.225 N/A SER 51.A OG MET 47.A O no hydrogen 3.391 N/A PHE 52.A N MET 48.A O no hydrogen 3.216 N/A ASP 53.A N LYS 50.A O no hydrogen 3.032 N/A LEU 54.A N SER 51.A O no hydrogen 3.237 N/A GLY 57.A N LEU 54.A O no hydrogen 2.909 N/A LYS 59.A N TYR 80.A O no hydrogen 2.720 N/A HIS 60.A NE2 ASP 62.A OD1 no hydrogen 2.813 N/A HIS 60.A NE2 ASP 62.A OD2 no hydrogen 3.083 N/A ASP 62.A N LEU 78.A O no hydrogen 2.867 N/A ARG 63.A NH1 HIS 252.A O no hydrogen 3.031 N/A ALA 64.A N ILE 76.A O no hydrogen 2.829 N/A LEU 65.A N TYR 248.A O no hydrogen 2.805 N/A HIS 66.A N ASP 74.A O no hydrogen 2.834 N/A HIS 66.A ND1 ASP 74.A OD2 no hydrogen 2.844 N/A GLY 68.A N TYR 72.A O no hydrogen 2.883 N/A TYR 72.A N ALA 69.A O no hydrogen 3.056 N/A GLN 73.A N SER 35.A O no hydrogen 2.596 N/A GLN 73.A NE2 GLN 67.A OE1 no hydrogen 3.142 N/A ASP 74.A N HIS 66.A O no hydrogen 2.762 N/A SER 75.A N ILE 33.A O no hydrogen 2.793 N/A ILE 76.A N ALA 64.A O no hydrogen 2.861 N/A PHE 77.A N ILE 31.A O no hydrogen 2.792 N/A LEU 78.A N ASP 62.A O no hydrogen 2.707 N/A ALA 79.A N ALA 29.A O no hydrogen 2.885 N/A TYR 80.A N HIS 60.A O no hydrogen 2.916 N/A TYR 80.A OH GLU 307.A OE1 no hydrogen 2.516 N/A TYR 80.A OH GLU 307.A OE2 no hydrogen 3.338 N/A TRP 81.A N VAL 27.A O no hydrogen 2.942 N/A TRP 81.A NE1 THR 56.A O no hydrogen 2.929 N/A THR 86.A N GLU 83.A O no hydrogen 3.100 N/A PHE 87.A N GLU 83.A O no hydrogen 3.351 N/A LYS 88.A N PRO 84.A O no hydrogen 2.907 N/A SER 89.A N ALA 85.A O no hydrogen 3.115 N/A SER 89.A OG ALA 85.A O no hydrogen 3.106 N/A TRP 90.A N THR 86.A O no hydrogen 2.880 N/A TRP 90.A NE1 SER 51.A O no hydrogen 2.726 N/A VAL 91.A N PHE 87.A O no hydrogen 2.937 N/A ALA 92.A N LYS 88.A O no hydrogen 3.102 N/A ASP 93.A N TRP 90.A O no hydrogen 3.014 N/A GLU 95.A N ASP 93.A OD1 no hydrogen 3.228 N/A GLN 97.A N ASP 93.A O no hydrogen 2.979 N/A GLN 97.A NE2 VAL 91.A O no hydrogen 2.932 N/A LYS 98.A N GLU 95.A O no hydrogen 3.384 N/A TRP 99.A N VAL 96.A O no hydrogen 3.006 N/A TRP 99.A NE1 SER 51.A OG no hydrogen 3.263 N/A TRP 100.A N VAL 96.A O no hydrogen 2.892 N/A SER 101.A N TYR 113.A OH no hydrogen 3.323 N/A LYS 103.A N TRP 100.A O no hydrogen 3.265 N/A ILE 105.A N GLY 102.A O no hydrogen 2.783 N/A ASN 108.A N ASP 106.A OD1 no hydrogen 2.822 N/A SER 109.A N ASP 106.A O no hydrogen 3.397 N/A SER 109.A OG ILE 111.A O no hydrogen 3.287 N/A ILE 111.A N SER 109.A OG no hydrogen 3.226 N/A GLY 112.A N GLN 34.A O no hydrogen 2.719 N/A TYR 113.A N VAL 321.A O no hydrogen 2.847 N/A TRP 114.A N GLY 32.A O no hydrogen 3.017 N/A TRP 114.A NE1 ASP 74.A OD1 no hydrogen 2.916 N/A SER 115.A N ILE 319.A O no hydrogen 2.933 N/A GLU 116.A N GLN 30.A O no hydrogen 2.903 N/A VAL 117.A N GLU 317.A O no hydrogen 3.025 N/A THR 118.A N PHE 28.A O no hydrogen 2.920 N/A THR 118.A OG1 PHE 28.A O no hydrogen 3.087 N/A THR 119.A N ASP 315.A O no hydrogen 2.807 N/A ILE 120.A N VAL 26.A O no hydrogen 2.632 N/A ILE 122.A N SER 24.A O no hydrogen 3.038 N/A HIS 124.A N PRO 121.A O no hydrogen 2.840 N/A HIS 124.A ND1 ASP 123.A OD1 no hydrogen 2.746 N/A GLU 126.A N VAL 308.A O no hydrogen 2.987 N/A THR 127.A OG1 HIS 129.A NE2 no hydrogen 2.923 N/A LEU 128.A N HIS 306.A O no hydrogen 2.996 N/A HIS 129.A N TRP 15.A O no hydrogen 2.810 N/A HIS 129.A ND1 ASN 136.A OD1 no hydrogen 3.156 N/A HIS 129.A NE2 THR 127.A OG1 no hydrogen 2.923 N/A SER 130.A N LEU 304.A O no hydrogen 2.886 N/A SER 130.A OG LEU 304.A O no hydrogen 3.263 N/A ASN 133.A N GLY 131.A O no hydrogen 2.799 N/A ASN 136.A N SER 139.A OG no hydrogen 2.850 N/A VAL 138.A N GLU 307.A OE2 no hydrogen 2.827 N/A SER 139.A N ASN 136.A O no hydrogen 2.856 N/A SER 139.A OG ASN 133.A O no hydrogen 2.809 N/A SER 139.A OG ASN 136.A O no hydrogen 3.165 N/A HIS 140.A N GLY 137.A O no hydrogen 3.081 N/A HIS 140.A ND1 GLY 137.A O no hydrogen 2.757 N/A PHE 141.A N VAL 138.A O no hydrogen 2.933 N/A VAL 142.A N VAL 138.A O no hydrogen 2.726 N/A LYS 145.A N THR 16.A O no hydrogen 2.800 N/A THR 147.A N ALA 14.A O no hydrogen 3.001 N/A VAL 149.A N THR 147.A OG1 no hydrogen 2.711 N/A HIS 150.A N GLU 148.A O no hydrogen 2.945 N/A TYR 152.A OH ASP 158.A OD2 no hydrogen 2.802 N/A ALA 155.A N TYR 152.A O no hydrogen 3.180 N/A ARG 157.A NE GLU 273.A OE1 no hydrogen 3.413 N/A ARG 157.A NE GLU 273.A OE2 no hydrogen 3.073 N/A ARG 157.A NH1 ASP 167.A O no hydrogen 2.836 N/A ARG 157.A NH2 GLU 273.A OE1 no hydrogen 2.908 N/A ASP 158.A N GLY 154.A O no hydrogen 2.950 N/A ARG 159.A N ALA 155.A O no hydrogen 2.702 N/A ARG 159.A NE GLU 126.A OE2 no hydrogen 2.746 N/A ARG 159.A NH1 VAL 149.A O no hydrogen 2.821 N/A ARG 159.A NH2 GLU 126.A OE1 no hydrogen 3.423 N/A ARG 159.A NH2 GLU 126.A OE2 no hydrogen 3.067 N/A ARG 159.A NH2 HIS 306.A NE2 no hydrogen 3.356 N/A MET 160.A N MET 156.A O no hydrogen 3.294 N/A MET 160.A N ARG 157.A O no hydrogen 3.145 N/A VAL 162.A N ASP 123.A O no hydrogen 2.975 N/A SER 163.A N MET 160.A O no hydrogen 3.206 N/A SER 163.A OG ARG 157.A O no hydrogen 2.651 N/A SER 163.A OG MET 160.A O no hydrogen 3.096 N/A ALA 164.A N PRO 161.A O no hydrogen 3.183 N/A SER 165.A N VAL 162.A O no hydrogen 2.969 N/A SER 165.A OG VAL 162.A O no hydrogen 3.262 N/A SER 166.A N VAL 162.A O no hydrogen 3.018 N/A LEU 168.A N SER 166.A OG no hydrogen 3.156 N/A ILE 180.A N PRO 331.A O no hydrogen 3.021 N/A ARG 182.A NH1 LEU 330.A O no hydrogen 2.485 N/A ARG 182.A NH1 PHE 332.A O no hydrogen 3.213 N/A ARG 182.A NH2 PHE 333.A O no hydrogen 2.995 N/A SER 184.A OG CYS 323.A O no hydrogen 2.796 N/A GLY 186.A N ASN 322.A OD1 no hydrogen 2.672 N/A LYS 187.A N SER 184.A O no hydrogen 3.314 N/A LYS 187.A NZ GLU 183.A O no hydrogen 3.325 N/A ARG 188.A NH1 SER 101.A O no hydrogen 3.036 N/A ARG 188.A NH2 GLY 102.A O no hydrogen 2.833 N/A ARG 188.A NH2 ILE 105.A O no hydrogen 3.180 N/A LEU 189.A N TYR 320.A O no hydrogen 2.856 N/A LYS 190.A N THR 336.A O no hydrogen 2.713 N/A VAL 191.A N LEU 318.A O no hydrogen 3.152 N/A THR 192.A N GLU 334.A O no hydrogen 2.987 N/A ASN 196.A N LEU 311.A O no hydrogen 2.692 N/A ASN 196.A ND2 GLU 169.A O no hydrogen 3.025 N/A CYS 198.A N TYR 266.A O no hydrogen 2.886 N/A CYS 198.A SG SER 309.A O no hydrogen 3.713 N/A LEU 199.A N SER 309.A O no hydrogen 2.774 N/A ILE 200.A N GLY 264.A O no hydrogen 2.920 N/A ARG 201.A N GLU 307.A O no hydrogen 2.864 N/A ARG 201.A NH1 ASP 62.A OD2 no hydrogen 3.165 N/A ARG 201.A NH1 TYR 80.A OH no hydrogen 2.864 N/A ARG 201.A NH2 ASP 62.A OD2 no hydrogen 3.137 N/A ARG 201.A NH2 GLU 249.A OE2 no hydrogen 3.100 N/A THR 202.A N VAL 262.A O no hydrogen 2.925 N/A ALA 203.A N TRP 305.A O no hydrogen 2.769 N/A GLN 204.A N SER 260.A O no hydrogen 2.916 N/A GLN 204.A NE2 THR 202.A O no hydrogen 3.222 N/A ASN 205.A N ALA 303.A O no hydrogen 2.886 N/A TRP 206.A N ASP 258.A O no hydrogen 3.111 N/A SER 207.A N ASN 205.A OD1 no hydrogen 3.153 N/A SER 207.A OG ASN 205.A OD1 no hydrogen 2.683 N/A CYS 209.A N TRP 206.A O no hydrogen 3.086 N/A ARG 214.A N GLY 210.A O no hydrogen 3.283 N/A GLU 215.A N SER 211.A O no hydrogen 3.229 N/A THR 216.A N GLY 212.A O no hydrogen 3.198 N/A THR 216.A OG1 GLY 212.A O no hydrogen 2.942 N/A THR 216.A OG1 HIS 296.A NE2 no hydrogen 2.766 N/A TYR 217.A N GLU 213.A O no hydrogen 2.890 N/A ILE 218.A N ARG 214.A O no hydrogen 2.939 N/A GLY 219.A N GLU 215.A O no hydrogen 2.850 N/A LEU 220.A N THR 216.A O no hydrogen 2.985 N/A VAL 221.A N TYR 217.A O no hydrogen 3.203 N/A GLU 222.A N TYR 217.A O no hydrogen 2.888 N/A THR 224.A N VAL 221.A O no hydrogen 3.038 N/A THR 224.A OG1 VAL 221.A O no hydrogen 3.094 N/A LEU 225.A N VAL 221.A O no hydrogen 3.207 N/A ILE 226.A N GLU 222.A O no hydrogen 2.995 N/A LYS 227.A N PRO 223.A O no hydrogen 3.088 N/A ALA 228.A N THR 224.A O no hydrogen 2.822 N/A ASN 229.A N LEU 225.A O no hydrogen 2.946 N/A THR 230.A N ILE 226.A O no hydrogen 2.812 N/A THR 230.A OG1 ILE 226.A O no hydrogen 3.202 N/A PHE 231.A N LYS 227.A O no hydrogen 2.874 N/A LEU 232.A N ALA 228.A O no hydrogen 2.949 N/A ARG 233.A N ASN 229.A O no hydrogen 3.002 N/A ARG 233.A NH1 SER 244.A O no hydrogen 3.065 N/A GLU 234.A N THR 230.A O no hydrogen 3.231 N/A GLU 234.A N PHE 231.A O no hydrogen 3.075 N/A ASN 235.A ND2 PHE 231.A O no hydrogen 2.973 N/A SER 237.A OG LEU 176.A O no hydrogen 3.282 N/A THR 239.A N ASN 235.A O no hydrogen 3.007 N/A THR 239.A OG1 ASN 235.A O no hydrogen 2.799 N/A THR 239.A OG1 ALA 236.A O no hydrogen 3.555 N/A GLY 240.A N ALA 236.A O no hydrogen 2.712 N/A CYS 241.A N THR 239.A OG1 no hydrogen 2.940 N/A CYS 241.A SG SER 243.A O no hydrogen 3.386 N/A CYS 241.A SG TYR 265.A O no hydrogen 3.720 N/A ILE 242.A N TYR 265.A O no hydrogen 2.871 N/A SER 244.A OG ASN 229.A OD1 no hydrogen 2.736 N/A LYS 245.A N ILE 263.A O no hydrogen 2.969 N/A VAL 247.A N CYS 261.A O no hydrogen 2.980 N/A TYR 248.A N LEU 65.A O no hydrogen 3.085 N/A TYR 248.A OH GLU 222.A OE2 no hydrogen 3.329 N/A GLU 249.A N LYS 259.A O no hydrogen 2.905 N/A GLN 250.A N ARG 63.A O no hydrogen 2.879 N/A GLN 250.A NE2 GLY 254.A O no hydrogen 3.231 N/A THR 251.A N GLU 255.A O no hydrogen 2.837 N/A GLY 254.A N THR 251.A O no hydrogen 2.741 N/A GLU 255.A N THR 251.A OG1 no hydrogen 3.068 N/A VAL 257.A N GLU 249.A O no hydrogen 2.940 N/A SER 260.A N GLN 204.A O no hydrogen 2.964 N/A SER 260.A OG GLN 204.A OE1 no hydrogen 2.846 N/A CYS 261.A N VAL 247.A O no hydrogen 3.004 N/A CYS 261.A SG GLU 249.A OE2 no hydrogen 3.858 N/A VAL 262.A N THR 202.A O no hydrogen 2.763 N/A ILE 263.A N LYS 245.A O no hydrogen 2.908 N/A GLY 264.A N ILE 200.A O no hydrogen 2.996 N/A TYR 265.A N SER 243.A O no hydrogen 2.953 N/A TYR 265.A OH GLU 116.A OE1 no hydrogen 2.797 N/A TYR 266.A N CYS 198.A O no hydrogen 2.736 N/A LEU 267.A N GLY 240.A O no hydrogen 2.842 N/A SER 268.A OG HIS 271.A ND1 no hydrogen 2.744 N/A HIS 271.A N SER 268.A OG no hydrogen 3.291 N/A HIS 271.A ND1 SER 268.A OG no hydrogen 2.744 N/A LEU 272.A N SER 268.A O no hydrogen 3.242 N/A GLU 273.A N MET 269.A O no hydrogen 2.791 N/A ARG 274.A N GLY 270.A O no hydrogen 2.786 N/A TRP 275.A N HIS 271.A O no hydrogen 3.009 N/A THR 276.A N LEU 272.A O no hydrogen 2.864 N/A THR 276.A OG1 LEU 272.A O no hydrogen 2.957 N/A HIS 277.A N GLU 273.A O no hydrogen 2.858 N/A ASP 278.A N ARG 274.A O no hydrogen 3.037 N/A HIS 279.A N TRP 275.A O no hydrogen 2.891 N/A HIS 279.A ND1 THR 281.A OG1 no hydrogen 2.448 N/A THR 281.A N HIS 279.A ND1 no hydrogen 3.154 N/A THR 281.A OG1 HIS 279.A ND1 no hydrogen 2.448 N/A LYS 283.A N HIS 279.A O no hydrogen 2.997 N/A ALA 284.A N PRO 280.A O no hydrogen 2.574 N/A ILE 285.A N THR 281.A O no hydrogen 3.200 N/A TYR 286.A N HIS 282.A O no hydrogen 2.787 N/A GLY 287.A N LYS 283.A O no hydrogen 2.977 N/A GLY 287.A N ALA 284.A O no hydrogen 2.930 N/A THR 288.A N ALA 284.A O no hydrogen 2.835 N/A THR 288.A OG1 ALA 284.A O no hydrogen 3.328 N/A THR 288.A OG1 ILE 285.A O no hydrogen 3.183 N/A PHE 289.A N ILE 285.A O no hydrogen 2.923 N/A TYR 290.A N TYR 286.A O no hydrogen 3.173 N/A GLU 291.A N GLY 287.A O no hydrogen 3.033 N/A MET 292.A N THR 288.A O no hydrogen 3.030 N/A LEU 293.A N PHE 289.A O no hydrogen 3.026 N/A LYS 294.A N TYR 290.A O no hydrogen 2.894 N/A ARG 295.A N MET 292.A O no hydrogen 3.088 N/A HIS 296.A NE2 THR 216.A OG1 no hydrogen 2.766 N/A PHE 298.A N LEU 293.A O no hydrogen 2.587 N/A LYS 299.A N HIS 296.A O no hydrogen 3.251 N/A ALA 303.A N ASN 205.A O no hydrogen 2.886 N/A LEU 304.A N SER 130.A OG no hydrogen 2.847 N/A TRP 305.A N ALA 203.A O no hydrogen 3.318 N/A HIS 306.A N LEU 128.A O no hydrogen 2.857 N/A HIS 306.A NE2 GLU 126.A OE1 no hydrogen 2.839 N/A GLU 307.A N ARG 201.A O no hydrogen 2.895 N/A VAL 308.A N GLU 126.A O no hydrogen 2.884 N/A SER 309.A N LEU 199.A O no hydrogen 2.823 N/A SER 309.A OG LEU 199.A O no hydrogen 3.459 N/A VAL 310.A N HIS 124.A O no hydrogen 3.033 N/A LEU 311.A N ILE 197.A O no hydrogen 2.785 N/A GLN 312.A N ASP 315.A OD2 no hydrogen 2.853 N/A GLN 312.A NE2 ASN 196.A OD1 no hydrogen 3.206 N/A SER 313.A N ASP 195.A OD1 no hydrogen 2.710 N/A SER 313.A OG ALA 193.A O no hydrogen 2.697 N/A ASP 315.A N GLN 312.A O no hydrogen 2.846 N/A ILE 316.A N SER 313.A O no hydrogen 3.482 N/A GLU 317.A N VAL 117.A O no hydrogen 2.900 N/A ILE 319.A N SER 115.A O no hydrogen 2.985 N/A TYR 320.A N LEU 189.A O no hydrogen 2.860 N/A TYR 320.A OH GLU 116.A OE2 no hydrogen 2.655 N/A VAL 321.A N TYR 113.A O no hydrogen 2.712 N/A ASN 322.A N LYS 187.A O no hydrogen 2.831 N/A ASN 322.A ND2 SER 109.A O no hydrogen 2.920 N/A ASN 322.A ND2 ILE 111.A O no hydrogen 3.015 N/A CYS 323.A SG TYR 113.A O no hydrogen 3.161 N/A CYS 323.A SG VAL 321.A O no hydrogen 3.629 N/A HIS 324.A N GLN 34.A OE1 no hydrogen 2.754 N/A HIS 324.A NE2 ASP 70.A OD2 no hydrogen 2.779 N/A SER 326.A N HIS 324.A ND1 no hydrogen 3.063 N/A SER 326.A OG HIS 324.A ND1 no hydrogen 3.132 N/A THR 327.A N HIS 324.A O no hydrogen 3.095 N/A THR 327.A OG1 HIS 324.A O no hydrogen 2.665 N/A PHE 329.A N TYR 320.A OH no hydrogen 2.979 N/A LEU 330.A N THR 327.A O no hydrogen 3.068 N/A PHE 332.A N PHE 329.A O no hydrogen 2.915 N/A THR 336.A N LYS 190.A O no hydrogen 2.669 N/A ILE 338.A N ARG 188.A O no hydrogen 2.876 N/A