Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7fd2_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 5.A N VAL 2.A O no hydrogen 3.304 N/A HIS 5.A ND1 THR 160.A OG1 no hydrogen 3.053 N/A PHE 6.A N VAL 2.A O no hydrogen 2.885 N/A PHE 6.A N THR 3.A O no hydrogen 3.171 N/A ASN 7.A N THR 3.A O no hydrogen 2.931 N/A TYR 9.A N PHE 6.A O no hydrogen 3.106 N/A THR 12.A N TYR 9.A O no hydrogen 2.597 N/A THR 12.A OG1 TYR 9.A O no hydrogen 2.259 N/A LYS 13.A N TRP 235.A O no hydrogen 2.802 N/A CYS 19.A N CYS 28.A O no hydrogen 3.201 N/A CYS 19.A SG ASP 21.A O no hydrogen 3.449 N/A CYS 22.A N GLN 26.A O no hydrogen 3.207 N/A CYS 22.A SG CYS 19.A O no hydrogen 4.023 N/A CYS 22.A SG CYS 28.A O no hydrogen 3.984 N/A CYS 22.A SG SER 30.A OG no hydrogen 3.628 N/A CYS 22.A SG ALA 124.A O no hydrogen 3.095 N/A ASP 24.A N CYS 22.A O no hydrogen 2.753 N/A GLN 26.A NE2 ASP 24.A OD2 no hydrogen 3.524 N/A CYS 28.A N CYS 19.A O no hydrogen 3.135 N/A GLU 35.A N GLN 49.A O no hydrogen 3.093 N/A ARG 38.A N LYS 47.A O no hydrogen 2.893 N/A ARG 38.A NH1 GLN 49.A OE1 no hydrogen 3.326 N/A ARG 38.A NH2 GLN 49.A OE1 no hydrogen 2.864 N/A GLU 40.A N TYR 156.A OH no hydrogen 3.227 N/A SER 42.A N THR 154.A OG1 no hydrogen 2.803 N/A SER 42.A OG THR 154.A OG1 no hydrogen 3.092 N/A GLY 44.A N ALA 41.A O no hydrogen 3.456 N/A ILE 46.A N ALA 103.A O no hydrogen 3.481 N/A LYS 47.A N ARG 38.A O no hydrogen 2.857 N/A LYS 47.A NZ PRO 257.A O no hydrogen 3.479 N/A LYS 47.A NZ PHE 258.A O no hydrogen 3.498 N/A ILE 48.A N ILE 101.A O no hydrogen 2.494 N/A VAL 50.A N HIS 99.A O no hydrogen 2.605 N/A GLN 53.A N ARG 68.A O no hydrogen 3.122 N/A GLN 53.A NE2 THR 12.A OG1 no hydrogen 3.010 N/A ILE 54.A N GLY 98.A O no hydrogen 2.885 N/A GLY 55.A N LYS 66.A O no hydrogen 3.015 N/A ASN 57.A N THR 61.A O no hydrogen 2.967 N/A ASN 57.A ND2 GLU 63.A OE1 no hydrogen 3.085 N/A GLY 60.A N ASN 57.A OD1 no hydrogen 3.034 N/A THR 61.A N ASN 57.A OD1 no hydrogen 2.936 N/A THR 61.A OG1 ASN 57.A OD1 no hydrogen 3.417 N/A GLU 63.A N GLY 55.A O no hydrogen 3.128 N/A LYS 66.A NZ ASN 65.A O no hydrogen 3.073 N/A ILE 67.A N ALA 78.A O no hydrogen 2.702 N/A ARG 68.A N GLN 53.A O no hydrogen 3.030 N/A ARG 68.A NE GLN 53.A OE1 no hydrogen 2.592 N/A ARG 68.A NH2 GLN 53.A OE1 no hydrogen 2.670 N/A TYR 69.A OH GLU 77.A O no hydrogen 3.122 N/A TYR 69.A OH ASP 117.A OD1 no hydrogen 2.216 N/A LYS 76.A N TYR 69.A O no hydrogen 3.295 N/A LYS 76.A NZ GLU 119.A OE1 no hydrogen 2.964 N/A ARG 80.A N ASN 65.A O no hydrogen 3.204 N/A ARG 80.A N ASN 79.A OD1 no hydrogen 2.461 N/A SER 82.A OG ASN 79.A O no hydrogen 3.246 N/A LEU 83.A N ARG 80.A O no hydrogen 3.071 N/A GLN 84.A N GLN 114.A O no hydrogen 2.965 N/A TYR 86.A N LYS 112.A O no hydrogen 2.790 N/A THR 87.A OG1 PRO 106.A O no hydrogen 3.084 N/A SER 88.A N THR 87.A OG1 no hydrogen 2.841 N/A SER 88.A OG PRO 107.A O no hydrogen 3.214 N/A CYS 91.A N VAL 85.A O no hydrogen 2.871 N/A ALA 92.A N TYR 104.A O no hydrogen 2.865 N/A ARG 94.A N VAL 102.A O no hydrogen 3.113 N/A MET 97.A N PHE 100.A O no hydrogen 2.958 N/A GLY 98.A N ILE 54.A O no hydrogen 2.884 N/A PHE 100.A N MET 97.A O no hydrogen 3.072 N/A ILE 101.A N ILE 48.A O no hydrogen 2.609 N/A VAL 102.A N GLY 95.A O no hydrogen 3.121 N/A ALA 103.A N ILE 46.A O no hydrogen 3.234 N/A TYR 104.A N ALA 92.A O no hydrogen 2.599 N/A TYR 104.A OH ASP 43.A OD2 no hydrogen 3.220 N/A GLY 108.A N HIS 131.A O no hydrogen 3.347 N/A LEU 111.A N VAL 127.A O no hydrogen 2.889 N/A LYS 112.A N TYR 86.A O no hydrogen 2.746 N/A VAL 113.A N CYS 125.A O no hydrogen 3.283 N/A GLN 114.A N GLN 84.A O no hydrogen 3.180 N/A PHE 115.A N GLN 123.A O no hydrogen 3.329 N/A GLN 116.A N SER 82.A OG no hydrogen 2.862 N/A ASP 117.A N HIS 121.A O no hydrogen 2.517 N/A ALA 118.A N TYR 69.A OH no hydrogen 3.126 N/A ALA 118.A N ASP 117.A OD1 no hydrogen 2.545 N/A SER 120.A N ASP 117.A O no hydrogen 2.775 N/A GLN 123.A N PHE 115.A O no hydrogen 3.268 N/A CYS 125.A N VAL 113.A O no hydrogen 3.156 N/A LYS 126.A N ASP 21.A O no hydrogen 2.593 N/A LYS 126.A NZ GLY 23.A O no hydrogen 3.162 N/A VAL 127.A N LEU 111.A O no hydrogen 3.368 N/A TYR 129.A N ASP 109.A O no hydrogen 3.225 N/A TYR 129.A OH ASP 39.A OD2 no hydrogen 2.864 N/A HIS 131.A NE2 CYS 105.A O no hydrogen 2.847 N/A ARG 138.A NE GLY 330.A O no hydrogen 2.814 N/A ARG 138.A NH1 THR 295.A OG1 no hydrogen 3.201 N/A ARG 138.A NH2 THR 295.A OG1 no hydrogen 3.260 N/A LYS 140.A N PRO 291.A O no hydrogen 3.044 N/A ILE 149.A N VAL 267.A O no hydrogen 3.275 N/A VAL 151.A N CYS 265.A O no hydrogen 3.061 N/A CYS 153.A N SER 263.A O no hydrogen 2.727 N/A THR 154.A OG1 GLU 40.A O no hydrogen 3.265 N/A THR 154.A OG1 SER 42.A OG no hydrogen 3.092 N/A THR 155.A N THR 261.A O no hydrogen 3.134 N/A THR 155.A OG1 ASP 43.A OD2 no hydrogen 3.248 N/A TYR 156.A OH GLU 40.A OE1 no hydrogen 2.776 N/A GLN 157.A N PRO 259.A O no hydrogen 2.869 N/A THR 160.A OG1 HIS 5.A ND1 no hydrogen 3.053 N/A THR 163.A OG1 GLU 165.A O no hydrogen 3.184 N/A THR 163.A OG1 GLU 165.A OE1 no hydrogen 3.237 N/A THR 163.A OG1 VAL 256.A O no hydrogen 2.720 N/A ILE 167.A N VAL 254.A O no hydrogen 2.597 N/A HIS 170.A N GLN 236.A O no hydrogen 2.786 N/A HIS 170.A NE2 ASP 246.A OD1 no hydrogen 3.002 N/A THR 171.A OG1 PRO 172.A O no hydrogen 3.414 N/A ILE 175.A N VAL 229.A O no hydrogen 2.969 N/A ASP 177.A N ALA 227.A O no hydrogen 3.036 N/A THR 179.A OG1 ASP 177.A OD1 no hydrogen 3.379 N/A THR 179.A OG1 ASP 177.A OD2 no hydrogen 2.780 N/A LEU 180.A N ASP 177.A O no hydrogen 3.474 N/A LEU 181.A N ILE 178.A O no hydrogen 3.227 N/A SER 182.A N LYS 189.A O no hydrogen 2.866 N/A SER 182.A OG LYS 189.A O no hydrogen 3.453 N/A ASN 187.A N SER 185.A O no hydrogen 3.064 N/A VAL 188.A N THR 216.A O no hydrogen 2.840 N/A LYS 189.A N SER 182.A O no hydrogen 3.202 N/A LYS 189.A NZ SER 213.A OG no hydrogen 3.320 N/A GLY 193.A N THR 191.A O no hydrogen 3.000 N/A LYS 195.A NZ LYS 195.A O no hydrogen 3.372 N/A LYS 195.A NZ THR 196.A OG1 no hydrogen 3.041 N/A ARG 198.A N ALA 228.A O no hydrogen 2.685 N/A THR 202.A N GLN 224.A O no hydrogen 3.331 N/A THR 202.A OG1 GLN 224.A OE1 no hydrogen 3.234 N/A THR 210.A OG1 GLY 209.A O no hydrogen 2.553 N/A THR 210.A OG1 THR 211.A O no hydrogen 3.433 N/A THR 211.A OG1 LYS 195.A O no hydrogen 2.541 N/A SER 212.A N THR 211.A OG1 no hydrogen 2.626 N/A SER 212.A OG THR 211.A O no hydrogen 2.399 N/A LYS 215.A NZ GLN 184.A OE1 no hydrogen 2.259 N/A LYS 215.A NZ ASN 187.A O no hydrogen 3.366 N/A THR 216.A N VAL 188.A O no hydrogen 3.372 N/A ASN 218.A N GLY 186.A O no hydrogen 2.748 N/A CYS 220.A SG LYS 221.A O no hydrogen 3.707 N/A ALA 228.A N ARG 198.A O no hydrogen 2.814 N/A VAL 229.A N ILE 175.A O no hydrogen 2.896 N/A THR 230.A N THR 196.A O no hydrogen 3.021 N/A THR 230.A OG1 ASP 174.A OD1 no hydrogen 3.239 N/A THR 230.A OG1 ASN 231.A OD1 no hydrogen 3.508 N/A ASN 231.A N THR 230.A OG1 no hydrogen 2.715 N/A GLN 236.A N HIS 170.A O no hydrogen 2.631 N/A SER 239.A N TYR 237.A O no hydrogen 2.633 N/A VAL 242.A N SER 239.A O no hydrogen 3.353 N/A ARG 244.A NH2 LEU 248.A O no hydrogen 2.648 N/A LEU 248.A N ASP 246.A OD1 no hydrogen 3.092 N/A SER 249.A OG ARG 250.A O no hydrogen 3.465 N/A LYS 251.A N MET 169.A O no hydrogen 2.915 N/A GLY 252.A N MET 169.A O no hydrogen 3.284 N/A VAL 254.A N ILE 167.A O no hydrogen 3.386 N/A VAL 256.A N GLU 165.A O no hydrogen 2.580 N/A THR 261.A N THR 155.A O no hydrogen 2.747 N/A SER 263.A N CYS 153.A O no hydrogen 2.886 N/A THR 264.A N SER 263.A OG no hydrogen 2.790 N/A THR 264.A OG1 GLU 150.A OE1 no hydrogen 3.245 N/A CYS 265.A N VAL 151.A O no hydrogen 2.817 N/A VAL 267.A N ILE 149.A O no hydrogen 2.759 N/A ARG 271.A NH1 HIS 287.A O no hydrogen 3.008 N/A THR 276.A N THR 283.A O no hydrogen 3.103 N/A LYS 279.A NZ GLY 360.A O no hydrogen 3.445 N/A ARG 280.A NH2 GLY 360.A O no hydrogen 2.588 N/A GLU 281.A N GLY 278.A O no hydrogen 3.061 N/A VAL 284.A N ARG 316.A O no hydrogen 3.208 N/A LYS 285.A N GLY 274.A O no hydrogen 2.861 N/A LYS 285.A NZ GLY 274.A O no hydrogen 2.666 N/A LEU 286.A N VAL 314.A O no hydrogen 3.365 N/A THR 292.A N ILE 310.A O no hydrogen 2.717 N/A THR 292.A OG1 GLU 139.A OE2 no hydrogen 3.301 N/A THR 292.A OG1 HIS 290.A O no hydrogen 2.739 N/A LEU 293.A N ARG 138.A O no hydrogen 3.314 N/A LEU 294.A N GLU 308.A O no hydrogen 3.262 N/A THR 295.A N ARG 328.A O no hydrogen 2.896 N/A ARG 297.A NH2 GLU 326.A OE2 no hydrogen 2.521 N/A LEU 299.A N GLY 324.A O no hydrogen 2.883 N/A TYR 306.A N TYR 296.A O no hydrogen 3.133 N/A TYR 306.A OH GLU 308.A OE2 no hydrogen 2.669 N/A ILE 310.A N THR 292.A O no hydrogen 2.674 N/A ARG 312.A NE ASP 311.A OD1 no hydrogen 3.436 N/A ARG 316.A NE GLU 308.A OE2 no hydrogen 2.523 N/A ARG 316.A NH1 GLU 315.A O no hydrogen 2.933 N/A ARG 316.A NH2 GLU 308.A OE1 no hydrogen 2.490 N/A ARG 316.A NH2 GLU 308.A OE2 no hydrogen 2.878 N/A ILE 318.A N LEU 282.A O no hydrogen 2.460 N/A ILE 325.A N LEU 337.A O no hydrogen 2.966 N/A GLU 326.A N ARG 297.A O no hydrogen 3.263 N/A TYR 327.A N VAL 335.A O no hydrogen 2.919 N/A ARG 328.A N THR 295.A O no hydrogen 2.674 N/A GLY 330.A N LEU 293.A O no hydrogen 3.034 N/A ASN 332.A N TRP 329.A O no hydrogen 3.378 N/A ASN 332.A ND2 ALA 270.A O no hydrogen 3.034 N/A VAL 335.A N TYR 327.A O no hydrogen 3.024 N/A ARG 336.A NE GLU 326.A OE1 no hydrogen 2.965 N/A ARG 336.A NH2 GLU 326.A OE1 no hydrogen 3.508 N/A LEU 337.A N ILE 325.A O no hydrogen 3.167 N/A ALA 339.A N THR 321.A O no hydrogen 3.324 N/A GLY 345.A N THR 343.A OG1 no hydrogen 3.333 N/A TRP 350.A N GLU 353.A OE2 no hydrogen 2.830 N/A ILE 354.A N TRP 350.A O no hydrogen 3.215 N/A ILE 355.A N PRO 351.A O no hydrogen 2.908 N/A LEU 356.A N HIS 352.A O no hydrogen 2.914 N/A TYR 357.A N GLU 353.A O no hydrogen 2.905 N/A TYR 358.A N ILE 354.A O no hydrogen 2.986 N/A TYR 359.A N LEU 356.A O no hydrogen 3.125 N/A GLY 360.A N LEU 356.A O no hydrogen 2.861 N/A THR 366.A N TYR 362.A O no hydrogen 3.436 N/A ILE 367.A N PRO 363.A O no hydrogen 2.950 N/A ALA 368.A N ALA 364.A O no hydrogen 2.931 N/A ALA 369.A N ALA 365.A O no hydrogen 2.897 N/A VAL 370.A N THR 366.A O no hydrogen 2.865 N/A SER 371.A N ILE 367.A O no hydrogen 2.932 N/A SER 371.A OG ILE 367.A O no hydrogen 2.968 N/A ALA 372.A N ALA 368.A O no hydrogen 2.898 N/A ALA 373.A N ALA 369.A O no hydrogen 2.879 N/A GLY 374.A N VAL 370.A O no hydrogen 2.886 N/A LEU 375.A N SER 371.A O no hydrogen 2.917 N/A ALA 376.A N ALA 372.A O no hydrogen 2.870 N/A VAL 377.A N ALA 373.A O no hydrogen 2.899 N/A VAL 378.A N GLY 374.A O no hydrogen 2.920 N/A LEU 379.A N LEU 375.A O no hydrogen 2.883 N/A SER 380.A N ALA 376.A O no hydrogen 2.870 N/A LEU 381.A N VAL 377.A O no hydrogen 2.919 N/A LEU 382.A N VAL 378.A O no hydrogen 2.902 N/A ALA 383.A N LEU 379.A O no hydrogen 2.882 N/A SER 384.A N SER 380.A O no hydrogen 2.942 N/A CYS 385.A N LEU 381.A O no hydrogen 2.923 N/A TYR 386.A N LEU 382.A O no hydrogen 2.876 N/A MET 387.A N ALA 383.A O no hydrogen 2.952 N/A PHE 388.A N SER 384.A O no hydrogen 2.927 N/A ALA 389.A N CYS 385.A O no hydrogen 2.909 N/A THR 390.A N TYR 386.A O no hydrogen 2.887 N/A THR 390.A OG1 TYR 386.A O no hydrogen 3.031 N/A ALA 391.A N MET 387.A O no hydrogen 2.964 N/A ARG 392.A N PHE 388.A O no hydrogen 2.923 N/A ARG 392.A NE CYS 415.A O no hydrogen 2.388 N/A ARG 393.A N ALA 389.A O no hydrogen 2.885 N/A LYS 394.A N THR 390.A O no hydrogen 2.875 N/A CYS 395.A N ALA 391.A O no hydrogen 3.002 N/A CYS 395.A N ARG 392.A O no hydrogen 3.129 N/A CYS 395.A SG ALA 391.A O no hydrogen 3.295 N/A LEU 396.A N ARG 392.A O no hydrogen 2.931 N/A LEU 396.A N ARG 393.A O no hydrogen 3.046 N/A THR 397.A OG1 ARG 393.A O no hydrogen 3.051 N/A LEU 401.A N THR 397.A O no hydrogen 3.353 N/A THR 402.A N PRO 398.A O no hydrogen 3.305 N/A THR 402.A OG1 PRO 398.A O no hydrogen 3.016 N/A THR 402.A OG1 TYR 399.A O no hydrogen 3.169 N/A GLY 412.A N PRO 408.A O no hydrogen 2.627 N/A VAL 413.A N VAL 409.A O no hydrogen 2.922 N/A LEU 414.A N THR 410.A O no hydrogen 2.896 N/A CYS 415.A N LEU 411.A O no hydrogen 3.175 N/A ALA 417.A N GLY 412.A O no hydrogen 2.883 N/A