Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7ffl_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 1.A N ILE 282.A O no hydrogen 3.445 N/A HIS 3.A N PHE 280.A O no hydrogen 3.147 N/A MET 7.A N ILE 276.A O no hydrogen 2.970 N/A SER 9.A OG VAL 273.A O no hydrogen 3.346 N/A GLN 10.A N PRO 8.A O no hydrogen 2.773 N/A GLY 12.A N PRO 33.A O no hydrogen 3.032 N/A TYR 15.A OH THR 5.A OG1 no hydrogen 3.332 N/A ASN 16.A ND2 LEU 339.A O no hydrogen 3.630 N/A ASN 16.A ND2 LYS 340.A O no hydrogen 3.376 N/A THR 17.A N ILE 29.A O no hydrogen 3.080 N/A VAL 19.A N LEU 27.A O no hydrogen 2.887 N/A ALA 25.A N THR 288.A O no hydrogen 2.757 N/A ILE 29.A N THR 17.A O no hydrogen 3.004 N/A SER 30.A N THR 136.A O no hydrogen 3.041 N/A ILE 31.A N TYR 15.A O no hydrogen 2.952 N/A THR 32.A N ASN 134.A O no hydrogen 3.369 N/A THR 32.A OG1 THR 32.A O no hydrogen 2.480 N/A THR 34.A N PHE 132.A O no hydrogen 2.816 N/A LYS 37.A N GLN 130.A O no hydrogen 2.841 N/A ILE 39.A N SER 128.A O no hydrogen 3.341 N/A THR 41.A N HIS 125.A O no hydrogen 3.085 N/A THR 41.A OG1 THR 126.A O no hydrogen 3.425 N/A ASN 43.A N LYS 123.A O no hydrogen 2.843 N/A GLU 45.A N ALA 121.A O no hydrogen 3.076 N/A TYR 46.A OH PRO 190.A O no hydrogen 2.486 N/A VAL 47.A N SER 205.A O no hydrogen 2.845 N/A THR 48.A N ALA 119.A O no hydrogen 3.115 N/A THR 48.A OG1 ILE 203.A O no hydrogen 2.745 N/A CYS 49.A SG HIS 50.A O no hydrogen 3.389 N/A HIS 50.A NE2 GLU 241.A OE1 no hydrogen 2.680 N/A TYR 51.A OH ALA 236.A O no hydrogen 2.430 N/A ASP 56.A N LYS 105.A O no hydrogen 3.033 N/A SER 57.A N ASP 56.A OD1 no hydrogen 2.686 N/A LYS 61.A N THR 101.A O no hydrogen 2.992 N/A LYS 61.A NZ SER 65.A O no hydrogen 3.048 N/A CYS 62.A SG TYR 93.A O no hydrogen 3.547 N/A CYS 63.A N ASN 100.A OD1 no hydrogen 3.060 N/A GLY 64.A N GLU 99.A O no hydrogen 3.313 N/A SER 65.A OG GLN 66.A O no hydrogen 3.333 N/A THR 71.A OG1 GLU 76.A OE2 no hydrogen 3.326 N/A ARG 73.A N GLU 76.A OE1 no hydrogen 3.285 N/A GLN 77.A N ALA 106.A O no hydrogen 2.756 N/A LYS 79.A N SER 104.A O no hydrogen 3.248 N/A PHE 81.A N GLN 102.A O no hydrogen 2.669 N/A THR 82.A OG1 ASN 100.A O no hydrogen 3.410 N/A GLY 83.A N ASN 100.A O no hydrogen 3.209 N/A MET 88.A N GLY 91.A O no hydrogen 2.961 N/A TYR 93.A N PRO 86.A O no hydrogen 3.168 N/A ASN 100.A ND2 VAL 84.A O no hydrogen 2.927 N/A ASN 100.A ND2 CYS 96.A O no hydrogen 3.107 N/A THR 101.A N LYS 61.A O no hydrogen 3.156 N/A THR 101.A OG1 GLY 64.A O no hydrogen 3.153 N/A GLN 102.A N PHE 81.A O no hydrogen 2.782 N/A VAL 103.A N ALA 59.A O no hydrogen 3.243 N/A SER 104.A N LYS 79.A O no hydrogen 3.170 N/A LYS 105.A NZ THR 69.A O no hydrogen 3.132 N/A LYS 105.A NZ THR 69.A OG1 no hydrogen 3.295 N/A ALA 106.A N GLN 77.A O no hydrogen 2.958 N/A TYR 107.A N GLY 54.A O no hydrogen 3.054 N/A VAL 108.A N PRO 74.A O no hydrogen 2.984 N/A MET 109.A N LYS 52.A O no hydrogen 3.132 N/A LYS 110.A NZ VAL 208.A O no hydrogen 2.622 N/A SER 111.A N HIS 50.A O no hydrogen 3.096 N/A SER 111.A OG HIS 50.A O no hydrogen 2.909 N/A SER 111.A OG TYR 51.A O no hydrogen 2.842 N/A CYS 114.A N SER 111.A O no hydrogen 3.459 N/A CYS 114.A SG SER 111.A O no hydrogen 3.234 N/A HIS 118.A NE2 GLU 120.A OE2 no hydrogen 3.150 N/A ALA 119.A N THR 48.A O no hydrogen 2.935 N/A GLU 120.A N GLN 179.A O no hydrogen 2.886 N/A ALA 121.A N TYR 46.A O no hydrogen 3.030 N/A TYR 122.A N ILE 177.A O no hydrogen 2.741 N/A TYR 122.A OH GLU 120.A OE1 no hydrogen 2.269 N/A LYS 123.A N ASN 43.A O no hydrogen 2.889 N/A LYS 123.A NZ GLU 191.A OE2 no hydrogen 3.270 N/A ALA 124.A N ARG 175.A O no hydrogen 3.269 N/A HIS 125.A N THR 41.A O no hydrogen 3.236 N/A SER 128.A N ILE 39.A O no hydrogen 3.112 N/A GLN 130.A N LYS 37.A O no hydrogen 3.194 N/A ALA 131.A N VAL 146.A O no hydrogen 3.112 N/A PHE 132.A N LYS 35.A O no hydrogen 3.052 N/A LEU 133.A N THR 144.A O no hydrogen 2.957 N/A ILE 135.A N ILE 142.A O no hydrogen 3.226 N/A THR 136.A N SER 30.A O no hydrogen 2.921 N/A THR 136.A OG1 SER 141.A OG no hydrogen 3.176 N/A VAL 137.A N HIS 140.A O no hydrogen 3.353 N/A SER 141.A OG THR 136.A OG1 no hydrogen 3.176 N/A ILE 142.A N ILE 135.A O no hydrogen 2.998 N/A THR 144.A N LEU 133.A O no hydrogen 3.075 N/A VAL 146.A N ALA 131.A O no hydrogen 2.867 N/A VAL 154.A N ILE 161.A O no hydrogen 3.127 N/A PHE 156.A N VAL 159.A O no hydrogen 3.408 N/A VAL 159.A N PHE 156.A O no hydrogen 2.616 N/A LYS 160.A N ASP 281.A O no hydrogen 3.262 N/A ILE 161.A N VAL 154.A O no hydrogen 3.388 N/A THR 162.A N ALA 279.A O no hydrogen 3.332 N/A GLY 164.A N PRO 277.A O no hydrogen 2.553 N/A THR 171.A OG1 PHE 173.A O no hydrogen 3.121 N/A ASP 174.A N ASN 186.A OD1 no hydrogen 3.365 N/A LYS 176.A NZ ASP 188.A OD1 no hydrogen 3.269 N/A LYS 176.A NZ PHE 189.A O no hydrogen 3.240 N/A LYS 176.A NZ GLU 191.A OE2 no hydrogen 3.005 N/A ILE 177.A N TYR 122.A O no hydrogen 3.179 N/A VAL 178.A N TYR 185.A O no hydrogen 2.859 N/A GLN 179.A N GLU 120.A O no hydrogen 2.799 N/A TYR 180.A N GLU 183.A O no hydrogen 2.725 N/A TYR 180.A OH ASP 117.A OD1 no hydrogen 2.805 N/A GLU 183.A N TYR 180.A O no hydrogen 2.901 N/A TYR 185.A N VAL 178.A O no hydrogen 2.706 N/A ASN 186.A ND2 PRO 172.A O no hydrogen 3.548 N/A TYR 192.A OH ASP 212.A O no hydrogen 3.299 N/A GLY 193.A N GLN 204.A OE1 no hydrogen 2.777 N/A ALA 194.A N GLU 191.A O no hydrogen 3.031 N/A GLN 204.A N TYR 214.A O no hydrogen 2.879 N/A GLN 204.A NE2 GLU 191.A O no hydrogen 3.011 N/A SER 205.A N VAL 47.A O no hydrogen 3.172 N/A SER 205.A OG THR 207.A O no hydrogen 2.778 N/A ARG 206.A NH1 GLU 45.A O no hydrogen 2.911 N/A TYR 214.A N GLN 204.A O no hydrogen 2.735 N/A ASN 216.A N ASP 202.A O no hydrogen 3.011 N/A ASN 216.A ND2 GLY 195.A O no hydrogen 3.127 N/A THR 217.A N ASP 75.A OD2 no hydrogen 3.149 N/A THR 217.A OG1 GLN 235.A OE1 no hydrogen 2.804 N/A VAL 220.A N THR 234.A O no hydrogen 3.123 N/A GLN 222.A N PRO 232.A O no hydrogen 3.163 N/A ARG 223.A NH2 THR 82.A O no hydrogen 3.436 N/A ARG 223.A NH2 GLY 83.A O no hydrogen 3.481 N/A THR 234.A N VAL 220.A O no hydrogen 2.967 N/A GLN 235.A NE2 THR 53.A OG1 no hydrogen 2.321 N/A ALA 236.A N THR 217.A O no hydrogen 3.157 N/A GLY 239.A N ASP 202.A OD2 no hydrogen 3.116 N/A GLN 242.A N SER 238.A O no hydrogen 3.093 N/A GLN 242.A NE2 ASP 246.A OD1 no hydrogen 3.439 N/A TRP 243.A N GLY 239.A O no hydrogen 2.910 N/A LYS 244.A N PHE 240.A O no hydrogen 2.959 N/A LYS 244.A NZ TYR 180.A OH no hydrogen 3.286 N/A LYS 245.A N GLU 241.A O no hydrogen 2.945 N/A ASP 246.A N GLN 242.A O no hydrogen 2.960 N/A LYS 247.A NZ TYR 185.A OH no hydrogen 3.255 N/A SER 250.A OG GLU 183.A OE1 no hydrogen 2.818 N/A LEU 251.A N ILE 184.A O no hydrogen 2.930 N/A LYS 252.A NZ GLU 183.A OE2 no hydrogen 3.470 N/A THR 254.A OG1 SER 250.A O no hydrogen 2.836 N/A CYS 259.A SG PRO 256.A O no hydrogen 3.275 N/A GLU 260.A N GLU 269.A O no hydrogen 2.874 N/A TYR 262.A N ARG 267.A O no hydrogen 3.349 N/A ARG 267.A N TYR 262.A O no hydrogen 3.452 N/A ARG 267.A NE GLU 269.A OE2 no hydrogen 2.886 N/A ARG 267.A NH1 PRO 265.A O no hydrogen 3.130 N/A ALA 268.A N LEU 38.A O no hydrogen 3.014 N/A GLU 269.A N GLU 260.A O no hydrogen 2.732 N/A ASN 270.A N ILE 36.A O no hydrogen 2.941 N/A ASN 270.A ND2 GLU 260.A OE1 no hydrogen 3.438 N/A ALA 272.A N PHE 257.A O no hydrogen 3.181 N/A VAL 273.A N CYS 271.A O no hydrogen 2.782 N/A SER 275.A N SER 167.A OG no hydrogen 3.273 N/A SER 275.A OG MET 7.A O no hydrogen 2.340 N/A ILE 276.A N MET 7.A O no hydrogen 3.029 N/A LEU 278.A N THR 5.A O no hydrogen 2.885 N/A PHE 280.A N HIS 3.A O no hydrogen 2.822 N/A ASP 281.A N LYS 160.A O no hydrogen 2.777 N/A LEU 286.A N PRO 283.A O no hydrogen 3.357 N/A THR 288.A OG1 LEU 286.A O no hydrogen 3.301 N/A THR 293.A N VAL 290.A O no hydrogen 3.064 N/A THR 293.A OG1 ARG 289.A O no hydrogen 3.381 N/A THR 293.A OG1 VAL 290.A O no hydrogen 2.676 N/A SER 297.A N SER 321.A O no hydrogen 3.023 N/A SER 297.A OG SER 321.A O no hydrogen 3.303 N/A GLU 300.A N LYS 319.A O no hydrogen 2.828 N/A THR 302.A N THR 317.A O no hydrogen 3.460 N/A THR 302.A OG1 THR 317.A O no hydrogen 3.558 N/A ASN 304.A N ILE 315.A O no hydrogen 2.686 N/A ASN 304.A ND2 THR 317.A OG1 no hydrogen 2.416 N/A GLU 305.A N ILE 315.A O no hydrogen 3.367 N/A VAL 307.A N GLY 313.A O no hydrogen 3.044 N/A TYR 308.A N HIS 381.A O no hydrogen 3.116 N/A SER 309.A N VAL 307.A O no hydrogen 2.817 N/A SER 309.A OG ASP 311.A OD1 no hydrogen 2.456 N/A SER 310.A OG PRO 391.A O no hydrogen 3.556 N/A ILE 315.A N GLU 305.A O no hydrogen 2.882 N/A ALA 316.A N ILE 354.A O no hydrogen 3.152 N/A THR 317.A N THR 302.A O no hydrogen 3.006 N/A THR 317.A OG1 THR 353.A OG1 no hydrogen 3.413 N/A VAL 318.A N ALA 352.A O no hydrogen 2.765 N/A LYS 319.A N GLU 300.A O no hydrogen 2.645 N/A SER 321.A OG TYR 320.A O no hydrogen 2.800 N/A ALA 322.A N GLU 348.A O no hydrogen 2.630 N/A SER 323.A N THR 295.A O no hydrogen 3.351 N/A SER 323.A OG THR 295.A O no hydrogen 3.253 N/A LYS 324.A NZ SER 291.A O no hydrogen 2.380 N/A LYS 327.A NZ GLU 139.A OE1 no hydrogen 2.989 N/A VAL 330.A N ALA 342.A O no hydrogen 3.361 N/A HIS 331.A N GLN 368.A O no hydrogen 2.971 N/A THR 338.A N SER 357.A O no hydrogen 3.032 N/A LYS 340.A N HIS 355.A O no hydrogen 2.864 N/A GLU 341.A N GLU 341.A OE1 no hydrogen 2.736 N/A VAL 344.A N CYS 328.A O no hydrogen 3.281 N/A THR 347.A N TYR 320.A OH no hydrogen 2.564 N/A THR 347.A OG1 TYR 320.A OH no hydrogen 2.921 N/A GLN 349.A NE2 SER 321.A OG no hydrogen 2.993 N/A GLY 350.A N THR 347.A OG1 no hydrogen 3.119 N/A ALA 352.A N VAL 318.A O no hydrogen 2.896 N/A THR 353.A OG1 THR 317.A OG1 no hydrogen 3.413 N/A ILE 354.A N ALA 316.A O no hydrogen 2.958 N/A PHE 356.A N GLY 314.A O no hydrogen 3.011 N/A SER 357.A N THR 338.A O no hydrogen 3.028 N/A SER 357.A OG ASP 311.A O no hydrogen 2.774 N/A THR 358.A OG1 THR 336.A O no hydrogen 3.231 N/A ASN 360.A N THR 358.A OG1 no hydrogen 2.850 N/A ILE 361.A N ALA 400.A O no hydrogen 3.456 N/A HIS 362.A ND1 ASP 379.A OD1 no hydrogen 2.448 N/A PHE 365.A N CYS 376.A O no hydrogen 3.270 N/A LEU 367.A N VAL 374.A O no hydrogen 2.513 N/A GLN 368.A N HIS 331.A O no hydrogen 2.884 N/A ILE 369.A N SER 372.A O no hydrogen 2.785 N/A CYS 370.A SG ALA 329.A O no hydrogen 3.199 N/A THR 371.A N ILE 369.A O no hydrogen 2.777 N/A SER 372.A N ILE 369.A O no hydrogen 3.319 N/A VAL 374.A N LEU 367.A O no hydrogen 2.873 N/A CYS 376.A N PHE 365.A O no hydrogen 3.030 N/A GLY 378.A N PRO 363.A O no hydrogen 3.343 N/A CYS 380.A N ILE 361.A O no hydrogen 3.330 N/A HIS 381.A N CYS 306.A O no hydrogen 3.130 N/A HIS 381.A ND1 CYS 306.A O no hydrogen 3.185 N/A HIS 390.A ND1 PRO 391.A O no hydrogen 2.954 N/A TYR 393.A N SER 310.A O no hydrogen 3.221 N/A THR 399.A OG1 PHE 398.A O no hydrogen 2.571 N/A ALA 406.A N SER 403.A O no hydrogen 2.531 N/A THR 408.A N LYS 404.A O no hydrogen 2.847 N/A THR 408.A OG1 LYS 404.A O no hydrogen 2.855 N/A TRP 409.A N THR 405.A O no hydrogen 2.972 N/A LEU 410.A N ALA 406.A O no hydrogen 2.930 N/A THR 411.A N TRP 407.A O no hydrogen 2.859 N/A THR 411.A OG1 TRP 407.A O no hydrogen 2.593 N/A SER 412.A N THR 408.A O no hydrogen 2.936 N/A SER 412.A OG THR 408.A O no hydrogen 3.355 N/A SER 412.A OG TRP 409.A O no hydrogen 2.816 N/A LEU 413.A N TRP 409.A O no hydrogen 2.954 N/A LEU 414.A N LEU 410.A O no hydrogen 2.902 N/A GLY 415.A N THR 411.A O no hydrogen 2.847 N/A GLY 415.A N SER 412.A O no hydrogen 3.296 N/A GLY 416.A N SER 412.A O no hydrogen 2.935 N/A VAL 419.A N GLY 415.A O no hydrogen 2.922 N/A ILE 420.A N GLY 416.A O no hydrogen 2.927 N/A ILE 421.A N SER 417.A O no hydrogen 2.961 N/A ILE 422.A N ALA 418.A O no hydrogen 2.938 N/A ILE 423.A N VAL 419.A O no hydrogen 2.951 N/A GLY 424.A N ILE 420.A O no hydrogen 2.933 N/A LEU 425.A N ILE 421.A O no hydrogen 2.982 N/A VAL 426.A N ILE 422.A O no hydrogen 2.938 N/A LEU 427.A N ILE 423.A O no hydrogen 2.883 N/A ALA 428.A N GLY 424.A O no hydrogen 2.936 N/A THR 429.A N LEU 425.A O no hydrogen 2.980 N/A THR 429.A OG1 LEU 425.A O no hydrogen 2.890 N/A ILE 430.A N VAL 426.A O no hydrogen 2.907 N/A VAL 431.A N LEU 427.A O no hydrogen 2.968 N/A ALA 432.A N ALA 428.A O no hydrogen 2.926 N/A MET 433.A N THR 429.A O no hydrogen 2.948 N/A TYR 434.A N ILE 430.A O no hydrogen 2.884 N/A VAL 435.A N VAL 431.A O no hydrogen 2.925 N/A LEU 436.A N ALA 432.A O no hydrogen 2.968 N/A THR 437.A N MET 433.A O no hydrogen 2.866 N/A THR 437.A OG1 MET 433.A O no hydrogen 2.599 N/A ASN 438.A N TYR 434.A O no hydrogen 2.908 N/A LYS 440.A N THR 437.A O no hydrogen 3.176 N/A HIS 441.A NE2 ASN 438.A OD1 no hydrogen 3.280 N/A