Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7fic_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 3.A N ASP 6.A OD2 no hydrogen 2.623 N/A ASP 6.A N ALA 3.A O no hydrogen 2.833 N/A PHE 7.A N LEU 4.A O no hydrogen 3.124 N/A GLU 8.A N ARG 25.A O no hydrogen 2.794 N/A GLY 10.A N LEU 23.A O no hydrogen 2.595 N/A LEU 13.A N VAL 21.A O no hydrogen 2.764 N/A ASN 20.A N VAL 37.A O no hydrogen 2.967 N/A ASN 20.A ND2 TYR 22.A OH no hydrogen 3.080 N/A VAL 21.A N GLY 14.A O no hydrogen 3.027 N/A TYR 22.A N LEU 35.A O no hydrogen 2.943 N/A LEU 23.A N ARG 11.A O no hydrogen 3.023 N/A ALA 24.A N LEU 33.A O no hydrogen 2.875 N/A ARG 25.A N GLU 8.A O no hydrogen 2.871 N/A GLU 26.A N PHE 31.A O no hydrogen 2.864 N/A LYS 27.A N ASP 6.A O no hydrogen 2.966 N/A SER 29.A N GLU 26.A OE1 no hydrogen 2.844 N/A SER 29.A OG GLU 26.A OE1 no hydrogen 3.330 N/A PHE 31.A N SER 29.A OG no hydrogen 3.313 N/A LEU 33.A N ALA 24.A O no hydrogen 2.906 N/A ALA 34.A N LEU 84.A O no hydrogen 2.873 N/A LEU 35.A N TYR 22.A O no hydrogen 2.832 N/A LYS 36.A N LEU 82.A O no hydrogen 3.001 N/A VAL 37.A N ASN 20.A O no hydrogen 2.772 N/A LEU 38.A N VAL 80.A O no hydrogen 2.814 N/A PHE 39.A N PHE 18.A O no hydrogen 3.102 N/A LYS 40.A N THR 78.A O no hydrogen 3.452 N/A GLN 42.A N PHE 39.A O no hydrogen 2.853 N/A LEU 43.A N PHE 39.A O no hydrogen 3.019 N/A LYS 45.A N ALA 41.A O no hydrogen 2.880 N/A ALA 46.A N GLN 42.A O no hydrogen 3.378 N/A LEU 52.A N VAL 48.A O no hydrogen 2.628 N/A ARG 53.A N GLU 49.A O no hydrogen 2.959 N/A ARG 54.A N HIS 50.A O no hydrogen 2.977 N/A GLU 55.A N GLN 51.A O no hydrogen 2.906 N/A VAL 56.A N LEU 52.A O no hydrogen 2.946 N/A GLU 57.A N ARG 53.A O no hydrogen 3.037 N/A ILE 58.A N ARG 54.A O no hydrogen 2.913 N/A GLN 59.A N GLU 55.A O no hydrogen 2.821 N/A SER 60.A N VAL 56.A O no hydrogen 2.957 N/A SER 60.A OG VAL 56.A O no hydrogen 3.385 N/A SER 60.A OG GLU 57.A O no hydrogen 2.845 N/A LEU 62.A N GLN 59.A O no hydrogen 2.970 N/A ARG 63.A N TYR 120.A OH no hydrogen 2.967 N/A ASN 66.A N HIS 64.A ND1 no hydrogen 2.948 N/A ASN 66.A ND2 GLU 113.A OE2 no hydrogen 3.278 N/A ASN 66.A ND2 LEU 144.A O no hydrogen 2.831 N/A ILE 67.A N HIS 64.A O no hydrogen 3.156 N/A LEU 68.A N ILE 146.A O no hydrogen 2.867 N/A ARG 69.A N GLU 85.A OE1 no hydrogen 2.925 N/A TYR 71.A N ILE 83.A O no hydrogen 2.773 N/A PHE 74.A N TYR 81.A O no hydrogen 2.949 N/A ASP 76.A N ARG 79.A O no hydrogen 2.897 N/A THR 78.A N ASP 76.A OD1 no hydrogen 3.179 N/A ARG 79.A N ASP 76.A OD1 no hydrogen 2.434 N/A VAL 80.A N LEU 38.A O no hydrogen 2.776 N/A TYR 81.A N PHE 74.A O no hydrogen 2.955 N/A TYR 81.A OH ASP 76.A OD2 no hydrogen 3.306 N/A ILE 83.A N GLY 72.A O no hydrogen 2.893 N/A LEU 84.A N ALA 34.A O no hydrogen 2.886 N/A GLU 85.A N ARG 69.A O no hydrogen 2.916 N/A LEU 89.A N LEU 138.A O no hydrogen 3.155 N/A VAL 92.A N LEU 136.A O no hydrogen 2.665 N/A TYR 93.A N PRO 133.A O no hydrogen 3.199 N/A ARG 94.A N THR 91.A OG1 no hydrogen 3.001 N/A GLU 95.A N THR 91.A O no hydrogen 3.213 N/A LEU 96.A N VAL 92.A O no hydrogen 2.821 N/A GLN 97.A N TYR 93.A O no hydrogen 3.003 N/A LYS 98.A N ARG 94.A O no hydrogen 2.886 N/A LEU 99.A N GLU 95.A O no hydrogen 2.909 N/A SER 100.A N LEU 96.A O no hydrogen 2.851 N/A LYS 101.A N LEU 99.A O no hydrogen 2.787 N/A PHE 102.A N PHE 185.A O no hydrogen 2.726 N/A ARG 106.A N ASP 103.A OD1 no hydrogen 2.518 N/A THR 107.A N ASP 103.A O no hydrogen 2.946 N/A THR 107.A OG1 ASP 103.A O no hydrogen 2.671 N/A ALA 108.A N GLU 104.A O no hydrogen 2.815 N/A THR 109.A N GLN 105.A O no hydrogen 2.931 N/A THR 109.A OG1 GLN 105.A O no hydrogen 2.849 N/A THR 109.A OG1 SER 251.A OG no hydrogen 3.196 N/A TYR 110.A N ARG 106.A O no hydrogen 2.917 N/A ILE 111.A N THR 107.A O no hydrogen 2.858 N/A THR 112.A N ALA 108.A O no hydrogen 2.774 N/A THR 112.A OG1 ALA 108.A O no hydrogen 2.728 N/A THR 112.A OG1 SER 250.A OG no hydrogen 2.965 N/A GLU 113.A N THR 109.A O no hydrogen 2.894 N/A LEU 114.A N TYR 110.A O no hydrogen 2.866 N/A ALA 115.A N ILE 111.A O no hydrogen 2.837 N/A ASN 116.A N THR 112.A O no hydrogen 2.920 N/A ASN 116.A ND2 PRO 253.A O no hydrogen 3.636 N/A ALA 117.A N GLU 113.A O no hydrogen 2.929 N/A LEU 118.A N LEU 114.A O no hydrogen 2.783 N/A SER 119.A N ALA 115.A O no hydrogen 2.855 N/A SER 119.A OG ASN 116.A O no hydrogen 2.965 N/A TYR 120.A N ASN 116.A O no hydrogen 2.986 N/A CYS 121.A N ALA 117.A O no hydrogen 2.942 N/A CYS 121.A SG ALA 117.A O no hydrogen 3.367 N/A HIS 122.A N LEU 118.A O no hydrogen 2.893 N/A HIS 122.A NE2 ASP 174.A OD2 no hydrogen 3.249 N/A SER 123.A N SER 119.A O no hydrogen 2.904 N/A SER 123.A OG TYR 120.A O no hydrogen 2.975 N/A LYS 124.A N TYR 120.A O no hydrogen 2.842 N/A ARG 125.A N HIS 122.A O no hydrogen 2.768 N/A VAL 126.A N CYS 121.A O no hydrogen 2.634 N/A ARG 129.A N ASP 174.A OD1 no hydrogen 3.369 N/A ARG 129.A NE HIS 128.A O no hydrogen 2.897 N/A ASP 130.A N ASP 148.A OD2 no hydrogen 2.918 N/A LYS 132.A NZ ASP 130.A OD2 no hydrogen 3.010 N/A GLU 134.A N GLU 134.A OE1 no hydrogen 2.687 N/A ASN 135.A N LYS 132.A O no hydrogen 2.792 N/A LEU 136.A N PRO 133.A O no hydrogen 3.248 N/A LEU 137.A N LYS 145.A O no hydrogen 2.909 N/A GLY 139.A N GLU 143.A O no hydrogen 2.661 N/A ALA 141.A N GLU 143.A OE1 no hydrogen 2.797 N/A GLY 142.A N GLY 139.A O no hydrogen 2.938 N/A GLU 143.A N GLU 143.A OE1 no hydrogen 2.966 N/A LEU 144.A N GLU 113.A OE2 no hydrogen 3.289 N/A LYS 145.A N LEU 137.A O no hydrogen 2.852 N/A LYS 145.A NZ PRO 65.A O no hydrogen 2.746 N/A LYS 145.A NZ GLU 85.A OE1 no hydrogen 3.555 N/A LYS 145.A NZ GLU 85.A OE2 no hydrogen 2.689 N/A ILE 146.A N ASN 66.A O no hydrogen 2.908 N/A ALA 147.A N ASN 135.A O no hydrogen 2.886 N/A THR 155.A OG1 TYR 197.A OH no hydrogen 2.985 N/A ASP 157.A N GLY 154.A O no hydrogen 3.141 N/A TYR 158.A OH GLU 184.A OE1 no hydrogen 2.508 N/A TYR 158.A OH GLU 184.A OE2 no hydrogen 3.421 N/A LEU 159.A N LEU 156.A O no hydrogen 3.062 N/A GLU 162.A N GLU 162.A OE1 no hydrogen 2.757 N/A MET 163.A N PRO 160.A O no hydrogen 3.269 N/A ILE 164.A N PRO 160.A O no hydrogen 3.462 N/A GLU 165.A N PRO 161.A O no hydrogen 2.953 N/A GLY 166.A N MET 163.A O no hydrogen 2.622 N/A ARG 167.A N GLU 162.A O no hydrogen 2.751 N/A ARG 167.A NH2 HIS 229.A NE2 no hydrogen 3.411 N/A ASP 174.A N GLU 171.A O no hydrogen 3.030 N/A LEU 175.A N LYS 172.A O no hydrogen 3.034 N/A TRP 176.A N LYS 172.A O no hydrogen 3.462 N/A SER 177.A N VAL 173.A O no hydrogen 3.050 N/A LEU 178.A N ASP 174.A O no hydrogen 3.133 N/A GLY 179.A N LEU 175.A O no hydrogen 3.088 N/A VAL 180.A N TRP 176.A O no hydrogen 2.947 N/A LEU 181.A N SER 177.A O no hydrogen 2.869 N/A CYS 182.A N LEU 178.A O no hydrogen 2.642 N/A TYR 183.A N GLY 179.A O no hydrogen 2.960 N/A TYR 183.A OH THR 210.A O no hydrogen 2.636 N/A GLU 184.A N VAL 180.A O no hydrogen 2.901 N/A PHE 185.A N LEU 181.A O no hydrogen 2.819 N/A LEU 186.A N CYS 182.A O no hydrogen 3.332 N/A LEU 186.A N TYR 183.A O no hydrogen 3.023 N/A VAL 187.A N TYR 183.A O no hydrogen 2.873 N/A VAL 187.A N GLU 184.A O no hydrogen 3.059 N/A GLY 188.A N GLU 184.A O no hydrogen 2.581 N/A LYS 189.A NZ GLU 193.A OE1 no hydrogen 3.045 N/A GLU 193.A N PRO 190.A O no hydrogen 3.511 N/A TYR 197.A OH THR 155.A OG1 no hydrogen 2.985 N/A GLU 199.A N THR 196.A OG1 no hydrogen 3.289 N/A THR 200.A N THR 196.A O no hydrogen 3.095 N/A THR 200.A OG1 PHE 192.A O no hydrogen 3.493 N/A THR 200.A OG1 THR 196.A O no hydrogen 3.358 N/A TYR 201.A N TYR 197.A O no hydrogen 2.903 N/A LYS 202.A N GLN 198.A O no hydrogen 2.900 N/A LYS 202.A NZ GLU 199.A OE1 no hydrogen 3.554 N/A LYS 202.A NZ GLU 199.A OE2 no hydrogen 3.005 N/A ARG 203.A N GLU 199.A O no hydrogen 2.940 N/A ARG 203.A NE GLU 199.A OE2 no hydrogen 3.109 N/A ARG 203.A NH2 GLU 199.A OE2 no hydrogen 2.527 N/A ILE 204.A N THR 200.A O no hydrogen 2.946 N/A SER 205.A N TYR 201.A O no hydrogen 2.899 N/A SER 205.A OG TYR 201.A O no hydrogen 2.972 N/A SER 205.A OG LYS 202.A O no hydrogen 3.321 N/A ARG 206.A N LYS 202.A O no hydrogen 3.131 N/A ARG 206.A NE GLU 208.A OE2 no hydrogen 2.714 N/A ARG 206.A NH2 GLU 208.A OE1 no hydrogen 3.259 N/A ARG 206.A NH2 GLU 208.A OE2 no hydrogen 3.053 N/A VAL 207.A N ILE 204.A O no hydrogen 2.913 N/A GLU 208.A N ARG 203.A O no hydrogen 2.833 N/A VAL 215.A N PRO 212.A O no hydrogen 3.293 N/A THR 216.A OG1 GLU 104.A OE1 no hydrogen 3.535 N/A THR 216.A OG1 GLU 104.A OE2 no hydrogen 2.548 N/A ARG 220.A N THR 216.A O no hydrogen 2.963 N/A ARG 220.A NE VAL 215.A O no hydrogen 2.617 N/A ARG 220.A NH2 ASP 213.A O no hydrogen 3.137 N/A ARG 220.A NH2 VAL 215.A O no hydrogen 3.297 N/A ASP 221.A N GLU 217.A O no hydrogen 2.881 N/A LEU 222.A N GLY 218.A O no hydrogen 3.016 N/A ILE 223.A N ALA 219.A O no hydrogen 2.961 N/A SER 224.A N ARG 220.A O no hydrogen 2.794 N/A SER 224.A OG ARG 220.A O no hydrogen 3.049 N/A ARG 225.A N.A ASP 221.A O no hydrogen 2.952 N/A ARG 225.A N.B ASP 221.A O no hydrogen 2.961 N/A ARG 225.A NE.A ASP 221.A OD1 no hydrogen 3.137 N/A ARG 225.A NE.A ASP 221.A OD2 no hydrogen 2.549 N/A ARG 225.A NH2.A ASP 221.A OD1 no hydrogen 3.201 N/A ARG 225.A NH2.B GLU 239.A OE1 no hydrogen 3.373 N/A LEU 226.A N LEU 222.A O no hydrogen 2.944 N/A LEU 226.A N ILE 223.A O no hydrogen 2.964 N/A LEU 227.A N ILE 223.A O no hydrogen 2.898 N/A SER 232.A OG ASN 230.A OD1 no hydrogen 3.200 N/A GLN 233.A N ASN 230.A O no hydrogen 3.094 N/A ARG 234.A N PRO 231.A O no hydrogen 2.937 N/A ARG 234.A NE LYS 228.A O no hydrogen 2.847 N/A ARG 234.A NH1 GLU 162.A OE1 no hydrogen 3.308 N/A ARG 234.A NH1 GLU 162.A OE2 no hydrogen 2.520 N/A ARG 234.A NH1 LYS 172.A O no hydrogen 3.360 N/A ARG 234.A NH2 GLU 162.A OE1 no hydrogen 2.814 N/A ARG 234.A NH2 LYS 228.A O no hydrogen 2.913 N/A MET 236.A N GLU 239.A OE2 no hydrogen 3.105 N/A GLU 239.A N MET 236.A O no hydrogen 3.183 N/A VAL 240.A N LEU 237.A O no hydrogen 2.793 N/A LEU 241.A N LEU 237.A O no hydrogen 2.891 N/A GLU 242.A N ARG 238.A O no hydrogen 3.022 N/A HIS 243.A N VAL 240.A O no hydrogen 3.041 N/A HIS 243.A NE2 ASP 221.A OD2 no hydrogen 2.784 N/A TRP 245.A N HIS 243.A ND1 no hydrogen 3.046 N/A TRP 245.A NE1 GLU 104.A OE2 no hydrogen 2.811 N/A THR 247.A N HIS 243.A O no hydrogen 2.872 N/A ALA 248.A N PRO 244.A O no hydrogen 2.878 N/A ASN 249.A N TRP 245.A O no hydrogen 2.980 N/A ASN 249.A N ILE 246.A O no hydrogen 3.011 N/A ASN 249.A ND2 TRP 245.A O no hydrogen 2.880 N/A SER 250.A N ILE 246.A O no hydrogen 2.631 N/A SER 250.A OG THR 112.A OG1 no hydrogen 2.965 N/A SER 250.A OG LYS 252.A O no hydrogen 2.824 N/A SER 251.A N THR 109.A OG1 no hydrogen 3.383 N/A SER 251.A OG THR 109.A OG1 no hydrogen 3.196 N/A LYS 252.A NZ GLU 113.A OE2 no hydrogen 3.033 N/A