Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7icf_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A ND2 HIS 43.A O no hydrogen 3.193 N/A THR 8.A N ASN 4.A O no hydrogen 2.758 N/A THR 8.A OG1 ASN 4.A O no hydrogen 3.486 N/A THR 8.A OG1 GLY 5.A O no hydrogen 3.020 N/A ASP 9.A N GLY 5.A O no hydrogen 2.692 N/A MET 10.A N GLY 6.A O no hydrogen 2.499 N/A LEU 11.A N ILE 7.A O no hydrogen 3.013 N/A THR 12.A N THR 8.A O no hydrogen 2.909 N/A THR 12.A OG1 THR 8.A O no hydrogen 3.102 N/A THR 12.A OG1 ASP 9.A O no hydrogen 3.075 N/A GLU 13.A N ASP 9.A O no hydrogen 2.919 N/A LEU 14.A N MET 10.A O no hydrogen 3.004 N/A LEU 14.A N LEU 11.A O no hydrogen 3.229 N/A ALA 15.A N LEU 11.A O no hydrogen 3.074 N/A ASN 16.A N THR 12.A O no hydrogen 3.092 N/A ASN 16.A ND2 THR 12.A O no hydrogen 3.623 N/A GLU 18.A N LEU 14.A O no hydrogen 2.823 N/A LYS 19.A N ALA 15.A O no hydrogen 3.264 N/A ASN 20.A N ASN 16.A O no hydrogen 2.855 N/A VAL 21.A N PHE 17.A O no hydrogen 3.175 N/A SER 22.A N PHE 17.A O no hydrogen 3.233 N/A SER 22.A OG PHE 17.A O no hydrogen 3.319 N/A SER 22.A OG GLU 18.A O no hydrogen 2.938 N/A SER 22.A OG GLU 18.A OE1 no hydrogen 2.305 N/A TYR 28.A N ALA 24.A O no hydrogen 2.579 N/A ASN 29.A N ILE 25.A O no hydrogen 3.088 N/A TYR 31.A N LYS 27.A O no hydrogen 2.841 N/A ARG 32.A N TYR 28.A O no hydrogen 3.171 N/A LYS 33.A N ASN 29.A O no hydrogen 3.463 N/A LYS 33.A NZ GLY 56.A O no hydrogen 2.358 N/A ALA 34.A N ALA 30.A O no hydrogen 3.492 N/A ALA 35.A N TYR 31.A O no hydrogen 3.345 N/A SER 36.A N ARG 32.A O no hydrogen 3.185 N/A SER 36.A N LYS 33.A O no hydrogen 2.992 N/A SER 36.A OG LYS 33.A O no hydrogen 2.926 N/A VAL 37.A N LYS 33.A O no hydrogen 2.785 N/A ILE 38.A N ALA 34.A O no hydrogen 2.806 N/A LYS 40.A N SER 36.A O no hydrogen 2.911 N/A TYR 41.A OH GLU 50.A OE2 no hydrogen 2.859 N/A LYS 46.A N GLU 50.A OE1 no hydrogen 2.414 N/A GLY 48.A N ASP 66.A OD1 no hydrogen 2.570 N/A GLU 50.A N SER 47.A OG no hydrogen 2.994 N/A ALA 51.A N SER 47.A O no hydrogen 3.040 N/A LYS 52.A N GLY 48.A O no hydrogen 2.697 N/A LEU 54.A N ALA 51.A O no hydrogen 2.668 N/A VAL 57.A N LEU 54.A O no hydrogen 2.741 N/A GLU 63.A N THR 59.A O no hydrogen 3.022 N/A ILE 65.A N ILE 61.A O no hydrogen 2.903 N/A ASP 66.A N ALA 62.A O no hydrogen 2.997 N/A GLU 67.A N GLU 63.A O no hydrogen 3.065 N/A PHE 68.A N LYS 64.A O no hydrogen 2.939 N/A LEU 69.A N ILE 65.A O no hydrogen 2.740 N/A ALA 70.A N ASP 66.A O no hydrogen 2.643 N/A THR 71.A N GLU 67.A O no hydrogen 2.902 N/A THR 71.A OG1 LYS 73.A O no hydrogen 3.390 N/A LYS 73.A N THR 71.A OG1 no hydrogen 3.223 N/A LYS 73.A NZ GLU 78.A OE1 no hydrogen 2.667 N/A ARG 75.A N GLU 67.A OE2 no hydrogen 3.004 N/A GLU 78.A N LEU 74.A O no hydrogen 3.121 N/A LYS 79.A N ARG 75.A O no hydrogen 2.486 N/A ILE 80.A N LYS 76.A O no hydrogen 3.175 N/A ARG 81.A N LEU 77.A O no hydrogen 3.344 N/A ARG 81.A NE GLU 13.A OE1 no hydrogen 3.005 N/A ARG 81.A NH2 GLU 13.A OE1 no hydrogen 3.196 N/A GLN 82.A N LYS 79.A O no hydrogen 3.175 N/A ASP 83.A N LYS 79.A O no hydrogen 3.276 N/A THR 85.A N ASP 83.A OD1 no hydrogen 3.414 N/A SER 86.A N ASP 83.A O no hydrogen 2.952 N/A SER 86.A OG ILE 80.A O no hydrogen 3.013 N/A SER 87.A N ASP 83.A O no hydrogen 2.825 N/A SER 87.A OG ASP 83.A O no hydrogen 2.738 N/A SER 88.A N ASP 84.A O no hydrogen 3.087 N/A SER 88.A OG ASP 84.A O no hydrogen 2.748 N/A ASN 90.A N SER 87.A O no hydrogen 2.829 N/A PHE 91.A N SER 87.A O no hydrogen 3.120 N/A PHE 91.A N SER 88.A O no hydrogen 3.253 N/A LEU 92.A N SER 88.A O no hydrogen 2.908 N/A THR 93.A OG1 ILE 89.A O no hydrogen 2.573 N/A ARG 94.A N PHE 91.A O no hydrogen 2.851 N/A ARG 94.A NE GLU 139.A OE2 no hydrogen 3.171 N/A ARG 94.A NH2 GLU 139.A OE1 no hydrogen 3.237 N/A VAL 95.A N LEU 92.A O no hydrogen 2.781 N/A SER 96.A OG HIS 127.A NE2 no hydrogen 2.959 N/A ILE 98.A N VAL 95.A O no hydrogen 2.767 N/A ALA 103.A N GLY 99.A O no hydrogen 2.897 N/A ARG 104.A N PRO 100.A O no hydrogen 2.659 N/A PHE 106.A N ALA 102.A O no hydrogen 2.967 N/A VAL 107.A N ALA 103.A O no hydrogen 3.334 N/A ASP 108.A N ARG 104.A O no hydrogen 3.061 N/A GLU 109.A N LYS 105.A O no hydrogen 3.022 N/A ILE 111.A N PHE 106.A O no hydrogen 2.707 N/A LYS 112.A N ASP 116.A OD2 no hydrogen 2.283 N/A THR 113.A N ASP 116.A OD2 no hydrogen 2.544 N/A ASP 116.A N THR 113.A OG1 no hydrogen 2.953 N/A LEU 117.A N THR 113.A O no hydrogen 2.563 N/A ARG 118.A N LEU 114.A O no hydrogen 2.843 N/A LYS 119.A N GLU 115.A O no hydrogen 2.848 N/A ASN 120.A N ASP 116.A O no hydrogen 3.149 N/A ASN 120.A N LEU 117.A O no hydrogen 2.825 N/A ASN 120.A ND2 ASP 116.A O no hydrogen 2.685 N/A GLU 121.A N ARG 118.A O no hydrogen 3.145 N/A LYS 123.A N ASN 120.A O no hydrogen 2.974 N/A LEU 124.A N GLU 121.A O no hydrogen 3.292 N/A HIS 127.A NE2 SER 96.A OG no hydrogen 2.959 N/A ARG 129.A N HIS 126.A O no hydrogen 2.847 N/A ARG 129.A NE GLU 121.A O no hydrogen 2.872 N/A ARG 129.A NH2 GLU 121.A O no hydrogen 3.523 N/A ARG 129.A NH2 ASP 122.A O no hydrogen 3.097 N/A ILE 130.A N HIS 126.A O no hydrogen 3.163 N/A GLY 131.A N HIS 127.A O no hydrogen 2.821 N/A LEU 132.A N GLN 128.A O no hydrogen 3.080 N/A LYS 133.A N ARG 129.A O no hydrogen 2.753 N/A TYR 134.A N ILE 130.A O no hydrogen 2.882 N/A PHE 138.A N TYR 134.A O no hydrogen 2.908 N/A GLU 139.A N GLY 136.A O no hydrogen 2.550 N/A LYS 140.A NZ ASP 137.A OD1 no hydrogen 3.392 N/A ARG 141.A NE SER 179.A OG no hydrogen 3.176 N/A ILE 142.A N SER 180.A O no hydrogen 2.336 N/A ARG 144.A N GLU 178.A O no hydrogen 3.041 N/A ARG 144.A NE ALA 177.A O no hydrogen 3.497 N/A GLU 146.A N PRO 143.A O no hydrogen 2.746 N/A MET 147.A N PRO 143.A O no hydrogen 2.587 N/A LEU 148.A N ARG 144.A O no hydrogen 2.900 N/A MET 150.A N GLU 146.A O no hydrogen 2.793 N/A GLN 151.A N MET 147.A O no hydrogen 2.923 N/A GLN 151.A NE2 LEU 148.A O no hydrogen 3.526 N/A ASP 152.A N LEU 148.A O no hydrogen 2.597 N/A ILE 153.A N GLN 149.A O no hydrogen 3.059 N/A VAL 154.A N MET 150.A O no hydrogen 2.893 N/A LEU 155.A N GLN 151.A O no hydrogen 2.832 N/A ASN 156.A N ASP 152.A O no hydrogen 3.130 N/A ASN 156.A N ILE 153.A O no hydrogen 3.193 N/A GLU 157.A N ILE 153.A O no hydrogen 3.178 N/A VAL 158.A N VAL 154.A O no hydrogen 3.030 N/A LYS 159.A N LEU 155.A O no hydrogen 3.378 N/A LYS 160.A N ASN 156.A O no hydrogen 2.941 N/A LYS 160.A NZ GLU 157.A OE1 no hydrogen 3.145 N/A VAL 161.A N GLU 157.A O no hydrogen 3.051 N/A ASP 162.A N VAL 158.A O no hydrogen 2.952 N/A ASP 162.A N LYS 159.A O no hydrogen 3.061 N/A GLU 164.A N ASP 162.A OD1 no hydrogen 2.750 N/A TYR 165.A N ASP 162.A O no hydrogen 3.437 N/A TYR 165.A OH LEU 202.A O no hydrogen 2.778 N/A THR 168.A N LEU 186.A O no hydrogen 3.166 N/A THR 168.A OG1 TYR 257.A OH no hydrogen 2.675 N/A CYS 170.A N ASP 184.A O no hydrogen 3.116 N/A CYS 170.A SG THR 168.A O no hydrogen 3.904 N/A GLY 171.A N PHE 264.A O no hydrogen 3.308 N/A SER 172.A OG SER 180.A OG no hydrogen 3.205 N/A ARG 174.A NH1 THR 265.A OG1 no hydrogen 2.558 N/A ARG 174.A NH1 GLU 308.A OE2 no hydrogen 3.524 N/A ARG 174.A NH2 GLU 308.A OE1 no hydrogen 3.279 N/A ARG 175.A N SER 172.A O no hydrogen 2.905 N/A ARG 175.A NH1 THR 265.A O no hydrogen 2.886 N/A GLY 176.A N PHE 173.A O no hydrogen 2.937 N/A SER 180.A N ILE 142.A O no hydrogen 2.606 N/A SER 180.A OG SER 172.A OG no hydrogen 3.205 N/A MET 183.A N ARG 246.A O no hydrogen 2.757 N/A VAL 185.A N ASP 248.A O no hydrogen 3.102 N/A LEU 186.A N THR 168.A O no hydrogen 2.787 N/A LEU 187.A N ARG 250.A O no hydrogen 2.779 N/A THR 188.A N ILE 166.A O no hydrogen 2.906 N/A THR 188.A OG1 HIS 189.A O no hydrogen 3.496 N/A THR 188.A OG1 ILE 252.A O no hydrogen 2.298 N/A HIS 189.A N THR 188.A OG1 no hydrogen 2.308 N/A HIS 189.A NE2 ASP 162.A OD2 no hydrogen 3.087 N/A SER 191.A N HIS 189.A ND1 no hydrogen 3.034 N/A SER 191.A OG GLN 199.A OE1 no hydrogen 3.335 N/A PHE 192.A N HIS 189.A O no hydrogen 2.604 N/A THR 193.A N SER 196.A OG no hydrogen 2.906 N/A THR 193.A OG1 ASP 255.A OD1 no hydrogen 2.762 N/A SER 194.A N ASP 255.A OD1 no hydrogen 2.753 N/A SER 194.A OG ASP 255.A OD2 no hydrogen 3.131 N/A SER 196.A OG THR 193.A O no hydrogen 3.071 N/A LEU 203.A N PRO 200.A O no hydrogen 2.546 N/A HIS 204.A N PRO 200.A O no hydrogen 3.156 N/A GLN 205.A N LYS 201.A O no hydrogen 2.383 N/A VAL 207.A N LEU 203.A O no hydrogen 3.087 N/A GLU 208.A N HIS 204.A O no hydrogen 2.814 N/A GLN 209.A N GLN 205.A O no hydrogen 3.391 N/A LEU 210.A N VAL 206.A O no hydrogen 2.897 N/A GLN 211.A N VAL 207.A O no hydrogen 3.405 N/A GLN 211.A N GLU 208.A O no hydrogen 2.833 N/A LYS 212.A N GLU 208.A O no hydrogen 2.932 N/A VAL 213.A N GLN 209.A O no hydrogen 3.210 N/A PHE 215.A N LEU 210.A O no hydrogen 2.803 N/A ILE 216.A N LEU 210.A O no hydrogen 3.376 N/A THR 217.A N VAL 230.A O no hydrogen 2.845 N/A THR 217.A OG1 ASP 218.A OD1 no hydrogen 2.848 N/A LEU 220.A N MET 228.A O no hydrogen 2.359 N/A SER 221.A N MET 228.A O no hydrogen 2.842 N/A GLY 223.A N LYS 226.A O no hydrogen 2.784 N/A PHE 227.A N ILE 249.A O no hydrogen 2.814 N/A MET 228.A N SER 221.A O no hydrogen 2.590 N/A GLY 229.A N ILE 247.A O no hydrogen 2.922 N/A VAL 230.A N ASP 218.A O no hydrogen 3.139 N/A CYS 231.A N ARG 245.A O no hydrogen 2.728 N/A CYS 231.A SG ARG 245.A O no hydrogen 3.758 N/A GLN 232.A N PHE 215.A O no hydrogen 2.677 N/A GLN 232.A NE2 GLU 241.A OE2 no hydrogen 3.332 N/A GLN 232.A NE2 TYR 242.A O no hydrogen 2.381 N/A HIS 244.A N ASP 137.A OD2 no hydrogen 2.469 N/A HIS 244.A ND1 ASP 137.A OD2 no hydrogen 3.094 N/A ARG 245.A N CYS 231.A O no hydrogen 3.089 N/A ARG 245.A NE GLU 146.A OE1 no hydrogen 3.326 N/A ARG 246.A NH1 ILE 247.A O no hydrogen 2.860 N/A ARG 246.A NH2 ASP 248.A OD1 no hydrogen 2.386 N/A ILE 247.A N GLY 229.A O no hydrogen 2.878 N/A ASP 248.A N MET 183.A O no hydrogen 2.638 N/A ILE 249.A N PHE 227.A O no hydrogen 3.161 N/A ARG 250.A NH1 ASP 184.A OD2 no hydrogen 2.934 N/A LEU 251.A N THR 225.A O no hydrogen 2.550 N/A LYS 254.A N PHE 192.A O no hydrogen 2.448 N/A GLN 256.A N PRO 253.A O no hydrogen 2.772 N/A TYR 257.A OH THR 168.A OG1 no hydrogen 2.675 N/A TYR 257.A OH LEU 186.A O no hydrogen 2.437 N/A GLY 260.A N GLN 256.A O no hydrogen 3.146 N/A VAL 261.A N TYR 257.A O no hydrogen 2.744 N/A LEU 262.A N TYR 258.A O no hydrogen 2.566 N/A TYR 263.A N CYS 259.A O no hydrogen 2.887 N/A PHE 264.A N GLY 260.A O no hydrogen 2.562 N/A THR 265.A N LEU 262.A O no hydrogen 2.690 N/A THR 265.A OG1 VAL 261.A O no hydrogen 2.980 N/A GLY 266.A N TYR 263.A O no hydrogen 2.862 N/A SER 267.A N ARG 325.A O no hydrogen 3.135 N/A SER 267.A OG ARG 325.A O no hydrogen 3.341 N/A ASN 271.A N SER 267.A O no hydrogen 3.200 N/A LYS 272.A N ASP 268.A O no hydrogen 3.116 N/A ASN 273.A N ILE 269.A O no hydrogen 3.178 N/A MET 274.A N PHE 270.A O no hydrogen 2.998 N/A ARG 275.A N ASN 271.A O no hydrogen 2.665 N/A ALA 276.A N LYS 272.A O no hydrogen 2.313 N/A HIS 277.A N ASN 273.A O no hydrogen 3.234 N/A HIS 277.A NE2 ILE 315.A O no hydrogen 2.613 N/A ALA 278.A N MET 274.A O no hydrogen 2.789 N/A LEU 279.A N ALA 276.A O no hydrogen 2.954 N/A GLU 280.A N HIS 277.A O no hydrogen 2.590 N/A LYS 281.A N HIS 277.A O no hydrogen 2.874 N/A LYS 281.A NZ GLN 316.A OE1 no hydrogen 2.915 N/A GLY 282.A N LEU 279.A O no hydrogen 3.345 N/A THR 284.A N ARG 291.A O no hydrogen 3.058 N/A ASN 286.A ND2 THR 289.A O no hydrogen 3.360 N/A ASN 286.A ND2 THR 289.A OG1 no hydrogen 2.851 N/A ARG 291.A N THR 284.A O no hydrogen 2.840 N/A LEU 293.A N GLY 282.A O no hydrogen 2.976 N/A THR 296.A OG1 VAL 298.A O no hydrogen 3.475 N/A LEU 303.A N ILE 290.A O no hydrogen 2.877 N/A ASP 306.A N ASP 310.A OD1 no hydrogen 3.249 N/A PHE 312.A N GLU 308.A O no hydrogen 3.455 N/A ASP 313.A N LYS 309.A O no hydrogen 2.941 N/A TYR 314.A N ASP 310.A O no hydrogen 2.828 N/A TYR 314.A OH PRO 304.A O no hydrogen 2.451 N/A ILE 315.A N ILE 311.A O no hydrogen 3.149 N/A GLN 316.A N ASP 313.A O no hydrogen 2.617 N/A TYR 319.A OH GLU 308.A OE1 no hydrogen 3.212 N/A ARG 320.A NH1 GLU 327.A OXT no hydrogen 3.135 N/A GLU 321.A N ASP 324.A OD1 no hydrogen 3.336 N/A ARG 325.A N PRO 322.A O no hydrogen 3.030 N/A ARG 325.A NE ARG 320.A O no hydrogen 3.323 N/A ARG 325.A NH1 GLU 308.A OE2 no hydrogen 2.931 N/A ARG 325.A NH2 GLU 308.A OE1 no hydrogen 2.870 N/A ARG 325.A NH2 ARG 320.A O no hydrogen 2.816 N/A