Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7k0i_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N GLU 6.A OE2 no hydrogen 3.327 N/A GLU 8.A N VAL 4.A O no hydrogen 3.017 N/A GLU 8.A N GLU 8.A OE1 no hydrogen 3.047 N/A GLU 9.A N LYS 5.A O no hydrogen 2.999 N/A LEU 10.A N GLU 6.A O no hydrogen 2.833 N/A ILE 11.A N LYS 7.A O no hydrogen 2.968 N/A GLU 12.A N GLU 8.A O no hydrogen 2.891 N/A GLU 13.A N GLU 9.A O no hydrogen 2.973 N/A TRP 14.A N LEU 10.A O no hydrogen 3.198 N/A ALA 29.A N HIS 27.A ND1 no hydrogen 3.266 N/A LEU 30.A N HIS 27.A O no hydrogen 3.006 N/A ILE 34.A N ASN 46.A OD1 no hydrogen 3.369 N/A SER 40.A OG HIS 41.A O no hydrogen 3.457 N/A HIS 41.A NE2 GLU 406.A OE1 no hydrogen 2.636 N/A THR 43.A OG1 PRO 38.A O no hydrogen 3.476 N/A VAL 44.A N THR 43.A OG1 no hydrogen 2.628 N/A VAL 45.A N LYS 48.A O no hydrogen 2.916 N/A ASN 46.A N ILE 34.A O no hydrogen 3.433 N/A ASN 46.A ND2 ASN 33.A OD1 no hydrogen 3.208 N/A LYS 48.A N VAL 45.A O no hydrogen 2.826 N/A LYS 48.A NZ ASN 46.A O no hydrogen 3.553 N/A GLU 49.A N GLU 49.A OE1 no hydrogen 2.851 N/A CYS 50.A N THR 43.A O no hydrogen 3.013 N/A CYS 50.A SG LYS 48.A O no hydrogen 3.161 N/A CYS 50.A SG MET 370.A O no hydrogen 3.650 N/A ILE 51.A N SER 373.A O no hydrogen 3.319 N/A PHE 53.A N ALA 375.A O no hydrogen 3.024 N/A SER 55.A OG ASN 52.A OD1 no hydrogen 2.561 N/A ASN 57.A N SER 55.A O no hydrogen 2.734 N/A LEU 61.A N ASN 57.A OD1 no hydrogen 3.241 N/A LYS 68.A N ASN 64.A O no hydrogen 3.166 N/A ALA 69.A N PRO 65.A O no hydrogen 2.894 N/A ALA 70.A N ARG 66.A O no hydrogen 2.942 N/A ALA 71.A N VAL 67.A O no hydrogen 2.949 N/A LEU 72.A N LYS 68.A O no hydrogen 2.882 N/A ALA 73.A N ALA 69.A O no hydrogen 2.938 N/A SER 74.A N ALA 70.A O no hydrogen 3.009 N/A SER 74.A OG PRO 293.A O no hydrogen 3.397 N/A LEU 75.A N ALA 71.A O no hydrogen 2.874 N/A LYS 76.A N LEU 72.A O no hydrogen 2.906 N/A LYS 77.A N ALA 73.A O no hydrogen 2.984 N/A TYR 78.A N SER 74.A O no hydrogen 2.937 N/A TYR 78.A OH ASP 93.A OD2 no hydrogen 2.831 N/A GLY 79.A N LEU 75.A O no hydrogen 3.036 N/A THR 82.A OG1 SER 290.A O no hydrogen 3.126 N/A THR 82.A OG1 SER 290.A OG no hydrogen 3.133 N/A ARG 86.A NH1 GLU 99.A OE2 no hydrogen 3.260 N/A ARG 86.A NH2 GLU 99.A OE2 no hydrogen 2.571 N/A ASP 97.A N ASP 93.A O no hydrogen 2.960 N/A LEU 98.A N VAL 94.A O no hydrogen 2.870 N/A GLU 99.A N HIS 95.A O no hydrogen 2.933 N/A ASP 100.A N LEU 96.A O no hydrogen 2.971 N/A ARG 101.A N ASP 97.A O no hydrogen 2.888 N/A ARG 101.A NH1 ASN 304.A OD1 no hydrogen 2.552 N/A ARG 101.A NH2 ASN 304.A OD1 no hydrogen 2.530 N/A ARG 101.A NH2 GLU 307.A OE2 no hydrogen 3.271 N/A LEU 102.A N LEU 98.A O no hydrogen 2.920 N/A ALA 103.A N GLU 99.A O no hydrogen 2.987 N/A LYS 104.A N ASP 100.A O no hydrogen 2.930 N/A PHE 105.A N ARG 101.A O no hydrogen 2.868 N/A MET 106.A N LEU 102.A O no hydrogen 2.969 N/A LYS 107.A N LYS 104.A O no hydrogen 3.296 N/A THR 108.A N ALA 103.A O no hydrogen 3.062 N/A THR 108.A OG1 MET 106.A O no hydrogen 3.050 N/A GLU 110.A N GLY 270.A O no hydrogen 2.961 N/A ILE 112.A N CYS 268.A O no hydrogen 2.860 N/A TYR 114.A N GLY 266.A O no hydrogen 2.852 N/A TYR 114.A OH GLN 278.A OE1 no hydrogen 2.996 N/A GLY 117.A N GLU 258.A OE2 no hydrogen 3.095 N/A ALA 122.A N PHE 118.A O no hydrogen 3.025 N/A SER 123.A OG ALA 119.A O no hydrogen 2.908 N/A ALA 124.A N THR 120.A O no hydrogen 2.933 N/A ALA 127.A N ALA 124.A O no hydrogen 3.319 N/A TYR 128.A OH VAL 274.A O no hydrogen 2.301 N/A SER 129.A N ILE 125.A O no hydrogen 3.093 N/A LYS 130.A NZ ALA 127.A O no hydrogen 3.345 N/A ILE 134.A N ARG 189.A O no hydrogen 3.175 N/A VAL 135.A N ASP 155.A O no hydrogen 3.026 N/A PHE 136.A N PHE 191.A O no hydrogen 2.797 N/A VAL 137.A N LYS 157.A O no hydrogen 3.044 N/A ASP 138.A N VAL 193.A O no hydrogen 3.350 N/A ALA 140.A N ASP 138.A OD1 no hydrogen 3.348 N/A CYS 142.A SG GLU 195.A OE2 no hydrogen 3.591 N/A GLN 146.A N CYS 142.A O no hydrogen 3.260 N/A GLN 146.A NE2 ALA 141.A O no hydrogen 3.057 N/A GLN 146.A NE2 GLU 386.A OE1 no hydrogen 3.539 N/A LYS 147.A N PHE 143.A O no hydrogen 2.925 N/A LYS 147.A NZ GLN 150.A OE1 no hydrogen 2.434 N/A GLY 148.A N ALA 144.A O no hydrogen 2.911 N/A LEU 149.A N ILE 145.A O no hydrogen 2.909 N/A GLN 150.A N GLN 146.A O no hydrogen 2.920 N/A ALA 151.A N LYS 147.A O no hydrogen 2.922 N/A SER 152.A N GLY 148.A O no hydrogen 3.435 N/A SER 152.A OG LEU 149.A O no hydrogen 3.000 N/A SER 154.A OG SER 129.A OG no hydrogen 3.182 N/A ASP 155.A N ASP 133.A O no hydrogen 2.837 N/A LYS 157.A N VAL 135.A O no hydrogen 2.732 N/A PHE 159.A N VAL 137.A O no hydrogen 3.266 N/A LYS 160.A N ASP 166.A OD2 no hydrogen 3.129 N/A HIS 161.A NE2 THR 203.A OG1 no hydrogen 2.660 N/A ASN 162.A ND2 ILE 204.A O no hydrogen 3.083 N/A ASP 163.A N LYS 160.A O no hydrogen 3.276 N/A LEU 167.A N ASP 163.A O no hydrogen 3.294 N/A GLU 168.A N MET 164.A O no hydrogen 2.891 N/A ARG 169.A N ALA 165.A O no hydrogen 2.931 N/A ARG 169.A NE ASP 166.A OD1 no hydrogen 3.091 N/A ARG 169.A NH1 ASP 166.A OD1 no hydrogen 2.873 N/A LEU 170.A N ASP 166.A O no hydrogen 2.954 N/A LEU 171.A N LEU 167.A O no hydrogen 2.899 N/A LYS 172.A N GLU 168.A O no hydrogen 2.904 N/A LYS 172.A NZ TYR 217.A OH no hydrogen 3.034 N/A GLU 173.A N ARG 169.A O no hydrogen 3.002 N/A GLN 174.A N LEU 170.A O no hydrogen 2.949 N/A GLN 174.A NE2 GLU 177.A OE1 no hydrogen 3.132 N/A GLU 175.A N LEU 171.A O no hydrogen 2.891 N/A ILE 176.A N LYS 172.A O no hydrogen 2.987 N/A GLU 177.A N GLU 173.A O no hydrogen 2.962 N/A ASP 178.A N GLN 174.A O no hydrogen 2.859 N/A GLN 179.A N GLU 175.A O no hydrogen 2.931 N/A LYS 180.A N ILE 176.A O no hydrogen 2.962 N/A ALA 185.A N ASN 181.A O no hydrogen 3.312 N/A VAL 187.A N LYS 184.A O no hydrogen 3.001 N/A THR 188.A OG1 LYS 184.A O no hydrogen 3.127 N/A ARG 189.A N ASP 133.A OD2 no hydrogen 2.946 N/A ARG 189.A NH2 TYR 128.A O no hydrogen 3.476 N/A ARG 190.A NH2 ASP 178.A OD2 no hydrogen 2.592 N/A PHE 191.A N ILE 134.A O no hydrogen 2.962 N/A ILE 192.A N ARG 220.A O no hydrogen 2.849 N/A VAL 194.A N PHE 222.A O no hydrogen 2.970 N/A GLY 196.A N GLU 224.A O no hydrogen 2.727 N/A TYR 198.A N THR 203.A O no hydrogen 3.104 N/A GLY 202.A N TYR 198.A O no hydrogen 2.813 N/A THR 203.A OG1 HIS 161.A NE2 no hydrogen 2.660 N/A CYS 205.A SG GLU 195.A O no hydrogen 3.417 N/A LEU 210.A N PRO 206.A O no hydrogen 3.280 N/A VAL 211.A N LEU 207.A O no hydrogen 2.910 N/A LEU 213.A N GLU 209.A O no hydrogen 2.922 N/A LYS 214.A N LEU 210.A O no hydrogen 2.885 N/A LYS 214.A NZ ASP 249.A O no hydrogen 3.398 N/A TYR 215.A N VAL 211.A O no hydrogen 2.955 N/A TYR 215.A OH ASP 249.A OD1 no hydrogen 3.306 N/A LYS 216.A N LYS 212.A O no hydrogen 2.909 N/A TYR 217.A N LEU 213.A O no hydrogen 2.917 N/A ALA 219.A N LYS 214.A O no hydrogen 3.274 N/A PHE 222.A N ILE 192.A O no hydrogen 2.880 N/A LEU 223.A N LEU 252.A O no hydrogen 2.944 N/A GLU 224.A N VAL 194.A O no hydrogen 2.939 N/A GLU 225.A N SER 254.A O no hydrogen 2.905 N/A SER 226.A OG GLU 224.A OE2 no hydrogen 2.766 N/A SER 226.A OG ASN 256.A OD1 no hydrogen 3.104 N/A SER 228.A N GLU 225.A O no hydrogen 2.776 N/A SER 228.A OG GLU 225.A O no hydrogen 3.332 N/A HIS 235.A N GLU 241.A OE2 no hydrogen 3.144 N/A GLY 236.A N GLY 233.A O no hydrogen 3.405 N/A ARG 237.A NH1 PHE 105.A O no hydrogen 3.290 N/A GLY 238.A N LEU 232.A O no hydrogen 3.256 N/A VAL 239.A N GLU 225.A OE2 no hydrogen 3.230 N/A HIS 242.A N GLY 238.A O no hydrogen 3.469 N/A TYR 243.A N VAL 239.A O no hydrogen 2.927 N/A TYR 243.A OH CYS 205.A O no hydrogen 3.247 N/A GLY 244.A N GLU 241.A O no hydrogen 3.240 N/A ASP 248.A N ASN 246.A OD1 no hydrogen 2.513 N/A ASP 251.A N ILE 221.A O no hydrogen 3.384 N/A ILE 253.A N CYS 269.A O no hydrogen 2.976 N/A SER 254.A N LEU 223.A O no hydrogen 2.920 N/A SER 254.A OG LEU 223.A O no hydrogen 3.385 N/A SER 254.A OG GLU 224.A OE1 no hydrogen 2.946 N/A ALA 255.A N PHE 267.A O no hydrogen 2.909 N/A ASN 256.A ND2 GLU 258.A OE1 no hydrogen 3.445 N/A SER 263.A N MET 257.A O no hydrogen 3.278 N/A SER 263.A OG LEU 295.A O no hydrogen 3.407 N/A GLY 266.A N TYR 114.A O no hydrogen 2.952 N/A PHE 267.A N ALA 255.A O no hydrogen 2.908 N/A CYS 268.A N ILE 112.A O no hydrogen 2.966 N/A CYS 268.A SG THR 120.A O no hydrogen 3.911 N/A CYS 268.A SG THR 120.A OG1 no hydrogen 2.935 N/A CYS 268.A SG GLN 278.A OE1 no hydrogen 3.748 N/A CYS 269.A N ILE 253.A O no hydrogen 2.867 N/A CYS 269.A SG ILE 253.A O no hydrogen 3.470 N/A GLY 270.A N GLU 110.A O no hydrogen 2.915 N/A SER 272.A N GLU 109.A OE1 no hydrogen 3.407 N/A SER 272.A OG GLU 110.A OE2 no hydrogen 2.930 N/A SER 272.A OG ASP 276.A OD2 no hydrogen 2.310 N/A VAL 274.A N ARG 271.A O no hydrogen 2.974 N/A ILE 275.A N ARG 271.A O no hydrogen 2.993 N/A ASP 276.A N SER 272.A O no hydrogen 2.943 N/A GLN 278.A N ILE 275.A O no hydrogen 2.818 N/A GLN 278.A NE2 TYR 128.A OH no hydrogen 3.017 N/A ARG 279.A NE GLU 110.A OE1 no hydrogen 3.115 N/A ARG 279.A NH2 GLU 99.A OE1 no hydrogen 3.021 N/A ARG 279.A NH2 GLU 110.A OE1 no hydrogen 3.018 N/A ARG 279.A NH2 ALA 111.A O no hydrogen 3.235 N/A LEU 280.A N HIS 277.A O no hydrogen 3.330 N/A SER 281.A N HIS 277.A O no hydrogen 2.949 N/A SER 281.A OG SER 281.A O no hydrogen 2.533 N/A GLY 282.A N GLN 278.A O no hydrogen 2.918 N/A TYR 285.A N GLY 282.A O no hydrogen 3.105 N/A CYS 286.A N GLY 282.A O no hydrogen 2.892 N/A CYS 286.A SG ARG 279.A O no hydrogen 3.344 N/A CYS 286.A SG GLY 282.A O no hydrogen 3.461 N/A PHE 287.A N GLN 283.A O no hydrogen 3.155 N/A SER 290.A N GLY 84.A O no hydrogen 3.355 N/A SER 290.A OG GLY 90.A O no hydrogen 2.776 N/A ALA 296.A N PRO 292.A O no hydrogen 3.337 N/A ALA 297.A N PRO 293.A O no hydrogen 2.932 N/A ALA 298.A N LEU 294.A O no hydrogen 2.940 N/A ALA 299.A N LEU 295.A O no hydrogen 2.924 N/A ILE 300.A N ALA 296.A O no hydrogen 2.932 N/A GLU 301.A N ALA 297.A O no hydrogen 2.947 N/A ALA 302.A N ALA 298.A O no hydrogen 2.914 N/A LEU 303.A N ALA 299.A O no hydrogen 2.909 N/A ASN 304.A N ILE 300.A O no hydrogen 2.935 N/A ILE 305.A N GLU 301.A O no hydrogen 2.957 N/A MET 306.A N ALA 302.A O no hydrogen 2.907 N/A GLU 307.A N LEU 303.A O no hydrogen 2.918 N/A GLU 308.A N ASN 304.A O no hydrogen 2.933 N/A VAL 315.A N GLY 311.A O no hydrogen 2.991 N/A LEU 316.A N ILE 312.A O no hydrogen 2.915 N/A LYS 317.A N PHE 313.A O no hydrogen 2.922 N/A GLU 318.A N ALA 314.A O no hydrogen 2.965 N/A LYS 319.A N VAL 315.A O no hydrogen 2.949 N/A CYS 320.A N LEU 316.A O no hydrogen 2.939 N/A CYS 320.A SG LEU 316.A O no hydrogen 3.191 N/A CYS 320.A SG SER 341.A O no hydrogen 3.594 N/A GLY 321.A N LYS 317.A O no hydrogen 2.957 N/A GLN 322.A N GLU 318.A O no hydrogen 2.930 N/A ILE 323.A N LYS 319.A O no hydrogen 2.960 N/A HIS 324.A N CYS 320.A O no hydrogen 2.928 N/A LYS 325.A N GLY 321.A O no hydrogen 2.939 N/A ALA 326.A N GLN 322.A O no hydrogen 2.951 N/A LEU 327.A N ILE 323.A O no hydrogen 2.933 N/A GLN 328.A NE2 HIS 324.A O no hydrogen 3.259 N/A LYS 334.A N GLN 347.A O no hydrogen 2.869 N/A VAL 336.A N HIS 345.A O no hydrogen 3.026 N/A SER 341.A N GLU 338.A O no hydrogen 3.031 N/A SER 341.A OG GLY 202.A O no hydrogen 3.221 N/A SER 341.A OG ALA 343.A O no hydrogen 3.308 N/A PHE 344.A N VAL 396.A O no hydrogen 2.942 N/A HIS 345.A N VAL 336.A O no hydrogen 3.101 N/A HIS 345.A ND1 SER 393.A OG no hydrogen 2.793 N/A HIS 345.A NE2 MET 199.A O no hydrogen 2.898 N/A LEU 346.A N ILE 394.A O no hydrogen 2.871 N/A GLN 347.A N LYS 334.A O no hydrogen 2.919 N/A GLU 349.A N GLY 332.A O no hydrogen 3.463 N/A SER 351.A OG THR 352.A O no hydrogen 3.147 N/A SER 351.A OG ASP 358.A OD2 no hydrogen 2.911 N/A THR 352.A N ASP 358.A OD1 no hydrogen 3.315 N/A THR 352.A OG1 SER 354.A O no hydrogen 3.022 N/A THR 352.A OG1 ASP 358.A OD1 no hydrogen 3.467 N/A ARG 355.A NH1 PRO 390.A O no hydrogen 3.009 N/A ARG 355.A NH2 PRO 390.A O no hydrogen 3.379 N/A VAL 359.A N ARG 355.A O no hydrogen 2.921 N/A ARG 360.A N GLU 356.A O no hydrogen 2.914 N/A ARG 360.A NH2 GLN 357.A OE1 no hydrogen 2.753 N/A LEU 361.A N GLN 357.A O no hydrogen 2.907 N/A LEU 362.A N ASP 358.A O no hydrogen 2.962 N/A GLN 363.A N VAL 359.A O no hydrogen 2.893 N/A GLN 363.A NE2 ASP 367.A OD1 no hydrogen 2.958 N/A GLN 363.A NE2 ASP 367.A OD2 no hydrogen 3.503 N/A GLU 364.A N ARG 360.A O no hydrogen 2.901 N/A ILE 365.A N LEU 361.A O no hydrogen 3.018 N/A VAL 366.A N LEU 362.A O no hydrogen 2.890 N/A ASP 367.A N GLN 363.A O no hydrogen 2.920 N/A GLN 368.A N GLU 364.A O no hydrogen 2.965 N/A CYS 369.A N ILE 365.A O no hydrogen 2.943 N/A CYS 369.A SG ILE 365.A O no hydrogen 3.180 N/A MET 370.A N VAL 366.A O no hydrogen 2.891 N/A ASN 371.A N ASP 367.A O no hydrogen 2.966 N/A ARG 372.A N CYS 369.A O no hydrogen 2.905 N/A ARG 372.A NH1 GLU 416.A OE1 no hydrogen 3.222 N/A ARG 372.A NH2 GLU 416.A OE1 no hydrogen 3.143 N/A SER 373.A N MET 370.A O no hydrogen 3.030 N/A SER 373.A OG GLU 49.A O no hydrogen 3.270 N/A SER 373.A OG SER 373.A O no hydrogen 2.552 N/A ILE 374.A N CYS 369.A O no hydrogen 3.197 N/A ALA 375.A N ILE 51.A O no hydrogen 3.087 N/A THR 377.A OG1 GLN 378.A O no hydrogen 3.523 N/A GLN 378.A NE2 VAL 359.A O no hydrogen 3.578 N/A ALA 379.A N SER 393.A O no hydrogen 2.970 N/A ARG 380.A NH2 GLN 363.A OE1 no hydrogen 3.380 N/A GLU 383.A N GLU 383.A OE2 no hydrogen 3.107 N/A GLU 385.A N LEU 382.A O no hydrogen 3.187 N/A GLU 386.A N LEU 382.A O no hydrogen 3.140 N/A SER 393.A OG HIS 345.A ND1 no hydrogen 2.793 N/A SER 393.A OG PRO 391.A O no hydrogen 3.468 N/A ILE 394.A N LEU 346.A O no hydrogen 2.930 N/A ARG 395.A N THR 377.A O no hydrogen 2.856 N/A VAL 396.A N PHE 344.A O no hydrogen 2.905 N/A VAL 398.A N PRO 342.A O no hydrogen 3.262 N/A THR 399.A OG1 ASN 57.A O no hydrogen 2.858 N/A VAL 400.A N PHE 58.A O no hydrogen 3.344 N/A LEU 407.A N THR 403.A O no hydrogen 3.164 N/A GLU 408.A N GLU 404.A O no hydrogen 2.959 N/A ARG 409.A N GLU 405.A O no hydrogen 2.904 N/A ALA 410.A N GLU 406.A O no hydrogen 2.887 N/A ALA 411.A N LEU 407.A O no hydrogen 2.959 N/A SER 412.A N GLU 408.A O no hydrogen 2.963 N/A SER 412.A OG GLU 416.A OE2 no hydrogen 3.372 N/A THR 413.A N ARG 409.A O no hydrogen 2.880 N/A THR 413.A OG1 ARG 409.A O no hydrogen 3.041 N/A ILE 414.A N ALA 410.A O no hydrogen 2.956 N/A LYS 415.A N ALA 411.A O no hydrogen 2.927 N/A GLU 416.A N SER 412.A O no hydrogen 2.972 N/A VAL 417.A N THR 413.A O no hydrogen 2.958 N/A ALA 418.A N ILE 414.A O no hydrogen 2.892 N/A GLN 419.A N LYS 415.A O no hydrogen 2.940 N/A ALA 420.A N GLU 416.A O no hydrogen 2.958 N/A VAL 421.A N VAL 417.A O no hydrogen 2.896 N/A LEU 422.A N ALA 418.A O no hydrogen 2.911 N/A LEU 423.A N GLN 419.A O no hydrogen 3.222 N/A