Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7k2j_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 1.A N THR 283.A O no hydrogen 3.398 N/A ILE 2.A N TYR 19.A O no hydrogen 3.008 N/A TYR 3.A N ALA 281.A O no hydrogen 2.744 N/A TYR 3.A OH MET 284.A O no hydrogen 2.570 N/A THR 4.A N GLU 17.A O no hydrogen 2.728 N/A ALA 5.A N GLY 279.A O no hydrogen 2.714 N/A GLY 6.A N TYR 15.A O no hydrogen 2.858 N/A GLY 7.A N ARG 36.A O no hydrogen 2.914 N/A PHE 9.A N GLN 11.A O no hydrogen 2.949 N/A SER 12.A N ASN 56.A O no hydrogen 3.119 N/A SER 12.A OG SER 37.A OG no hydrogen 3.124 N/A SER 12.A OG ARG 54.A O no hydrogen 3.157 N/A LEU 13.A N GLY 7.A O no hydrogen 3.052 N/A GLU 17.A N THR 4.A O no hydrogen 3.076 N/A ALA 18.A N LEU 27.A O no hydrogen 3.091 N/A TYR 19.A N ILE 2.A O no hydrogen 2.596 N/A ASN 20.A N THR 25.A O no hydrogen 3.124 N/A SER 22.A N ASN 20.A OD1 no hydrogen 2.918 N/A ASP 23.A N ASN 20.A OD1 no hydrogen 2.773 N/A GLY 24.A N ASN 20.A O no hydrogen 2.985 N/A THR 25.A OG1 ASP 23.A OD2 no hydrogen 3.034 N/A TRP 26.A NE1 ARG 270.A O no hydrogen 2.964 N/A LEU 27.A N ALA 18.A O no hydrogen 2.838 N/A ARG 28.A NH2 ASP 31.A OD1 no hydrogen 3.140 N/A LEU 29.A N LEU 16.A O no hydrogen 2.904 N/A ALA 30.A N ASN 75.A OD1 no hydrogen 3.377 N/A LEU 32.A N SER 14.A O no hydrogen 2.752 N/A ARG 36.A N LEU 13.A O no hydrogen 2.995 N/A ARG 36.A NE GLY 52.A O no hydrogen 3.190 N/A ARG 36.A NH2 ALA 50.A O no hydrogen 2.960 N/A ARG 36.A NH2 GLY 52.A O no hydrogen 3.116 N/A SER 37.A N ARG 54.A O no hydrogen 2.782 N/A SER 37.A OG SER 12.A OG no hydrogen 3.124 N/A SER 37.A OG ARG 54.A O no hydrogen 3.515 N/A GLY 38.A N GLY 277.A O no hydrogen 2.894 N/A ALA 40.A N VAL 51.A O no hydrogen 2.976 N/A CYS 42.A N TYR 49.A O no hydrogen 3.059 N/A VAL 44.A N LEU 47.A O no hydrogen 3.098 N/A LEU 47.A N VAL 44.A O no hydrogen 2.928 N/A LEU 48.A N TYR 70.A O no hydrogen 2.891 N/A TYR 49.A N CYS 42.A O no hydrogen 2.667 N/A ALA 50.A N ASP 68.A O no hydrogen 2.731 N/A VAL 51.A N ALA 40.A O no hydrogen 2.750 N/A GLY 52.A N ALA 66.A O no hydrogen 3.093 N/A GLY 53.A N ARG 87.A O no hydrogen 2.877 N/A ARG 54.A N SER 37.A O no hydrogen 2.630 N/A ARG 54.A NE ASP 63.A OD1 no hydrogen 2.713 N/A ARG 54.A NH1 ASP 63.A OD1 no hydrogen 3.544 N/A ARG 54.A NH2 ASN 56.A OD1 no hydrogen 3.295 N/A ASN 55.A N THR 62.A O no hydrogen 2.838 N/A ASN 56.A N SER 12.A OG no hydrogen 2.672 N/A SER 57.A N GLY 60.A O no hydrogen 2.840 N/A SER 57.A OG ASN 55.A OD1 no hydrogen 2.503 N/A GLY 60.A N SER 57.A O no hydrogen 3.001 N/A THR 62.A N ASN 55.A O no hydrogen 3.061 N/A SER 64.A N GLY 53.A O no hydrogen 2.859 N/A ALA 66.A N SER 64.A OG no hydrogen 3.019 N/A ASP 68.A N ALA 50.A O no hydrogen 3.143 N/A CYS 69.A N SER 78.A O no hydrogen 2.843 N/A CYS 69.A SG SER 78.A O no hydrogen 3.768 N/A TYR 70.A N LEU 48.A O no hydrogen 2.708 N/A TYR 70.A OH ASN 75.A OD1 no hydrogen 2.349 N/A ASN 71.A N GLN 76.A O no hydrogen 2.991 N/A MET 73.A N ASN 71.A OD1 no hydrogen 3.064 N/A THR 74.A OG1 ASN 71.A O no hydrogen 3.428 N/A ASN 75.A N ASN 71.A O no hydrogen 2.700 N/A TRP 77.A NE1 ALA 30.A O no hydrogen 2.935 N/A SER 78.A N CYS 69.A O no hydrogen 2.750 N/A CYS 80.A N LEU 67.A O no hydrogen 2.675 N/A ALA 81.A N ASP 122.A OD1 no hydrogen 2.927 N/A MET 83.A N SER 65.A O no hydrogen 2.799 N/A SER 84.A N GLU 115.A OE1 no hydrogen 3.039 N/A SER 84.A N GLU 115.A OE2 no hydrogen 3.010 N/A SER 84.A OG GLU 115.A OE1 no hydrogen 3.057 N/A SER 84.A OG GLU 115.A OE2 no hydrogen 2.494 N/A ARG 87.A N SER 64.A O no hydrogen 2.847 N/A ARG 87.A NE GLU 115.A OE2 no hydrogen 3.193 N/A ARG 87.A NH1 GLY 103.A O no hydrogen 2.819 N/A ARG 87.A NH1 SER 113.A O no hydrogen 3.056 N/A ARG 87.A NH2 SER 113.A OG no hydrogen 3.138 N/A ARG 87.A NH2 GLU 115.A OE2 no hydrogen 3.052 N/A ASN 88.A N SER 105.A O no hydrogen 2.792 N/A ARG 89.A N GLY 38.A O no hydrogen 2.921 N/A GLY 91.A N VAL 102.A O no hydrogen 3.069 N/A GLY 93.A N TYR 100.A O no hydrogen 3.083 N/A ILE 95.A N HIS 98.A O no hydrogen 2.910 N/A HIS 98.A N ILE 95.A O no hydrogen 2.995 N/A ILE 99.A N TYR 117.A O no hydrogen 3.069 N/A TYR 100.A N GLY 93.A O no hydrogen 2.816 N/A ALA 101.A N GLU 115.A O no hydrogen 2.821 N/A VAL 102.A N GLY 91.A O no hydrogen 2.735 N/A GLY 103.A N SER 113.A O no hydrogen 3.258 N/A GLY 104.A N ARG 134.A O no hydrogen 3.036 N/A SER 105.A N ASN 88.A O no hydrogen 2.736 N/A SER 105.A OG ASN 88.A O no hydrogen 3.531 N/A HIS 106.A N ILE 109.A O no hydrogen 2.834 N/A GLY 107.A N ASP 63.A OD2 no hydrogen 2.591 N/A ILE 109.A N HIS 106.A O no hydrogen 2.988 N/A HIS 111.A N GLY 104.A O no hydrogen 2.909 N/A HIS 111.A NE2 PRO 86.A O no hydrogen 2.924 N/A GLU 115.A N ALA 101.A O no hydrogen 3.072 N/A ARG 116.A N HIS 125.A O no hydrogen 2.712 N/A ARG 116.A NH1 GLU 118.A OE2 no hydrogen 2.911 N/A TYR 117.A N ILE 99.A O no hydrogen 2.687 N/A TYR 117.A OH ASP 122.A OD1 no hydrogen 2.843 N/A GLU 118.A N GLU 123.A O no hydrogen 2.748 N/A ARG 121.A N GLU 118.A O no hydrogen 3.205 N/A GLU 123.A N GLU 118.A O no hydrogen 3.358 N/A TRP 124.A NE1 ALA 81.A O no hydrogen 2.763 N/A HIS 125.A N ARG 116.A O no hydrogen 2.803 N/A HIS 125.A NE2 GLU 123.A OE1 no hydrogen 2.988 N/A VAL 127.A N VAL 114.A O no hydrogen 2.841 N/A ALA 128.A N ASN 169.A OD1 no hydrogen 3.293 N/A MET 130.A N ASN 112.A O no hydrogen 2.794 N/A LEU 131.A N GLU 162.A OE2 no hydrogen 2.695 N/A THR 132.A OG1 GLU 162.A OE1 no hydrogen 2.878 N/A ARG 133.A NH1 HIS 110.A O no hydrogen 2.770 N/A ARG 134.A N HIS 111.A O no hydrogen 2.949 N/A ARG 134.A NE GLU 162.A OE1 no hydrogen 2.957 N/A ARG 134.A NH1 GLY 150.A O no hydrogen 2.850 N/A ARG 134.A NH1 SER 160.A O no hydrogen 2.946 N/A ARG 134.A NH2 GLU 162.A OE1 no hydrogen 2.708 N/A ILE 135.A N PHE 152.A O no hydrogen 2.931 N/A GLY 136.A N ARG 89.A O no hydrogen 2.939 N/A GLY 138.A N VAL 149.A O no hydrogen 3.092 N/A ALA 140.A N TYR 147.A O no hydrogen 2.916 N/A LEU 142.A N LEU 145.A O no hydrogen 3.040 N/A LEU 145.A N LEU 142.A O no hydrogen 3.136 N/A LEU 146.A N TYR 164.A O no hydrogen 3.216 N/A TYR 147.A N ALA 140.A O no hydrogen 2.664 N/A ALA 148.A N GLU 162.A O no hydrogen 3.030 N/A VAL 149.A N GLY 138.A O no hydrogen 2.753 N/A GLY 150.A N SER 160.A O no hydrogen 2.927 N/A GLY 151.A N ARG 181.A O no hydrogen 2.728 N/A PHE 152.A N ILE 135.A O no hydrogen 2.871 N/A ASP 153.A N ASN 156.A O no hydrogen 2.973 N/A THR 155.A N ASP 153.A OD1 no hydrogen 2.736 N/A ASN 156.A N ASP 153.A OD1 no hydrogen 2.668 N/A LEU 158.A N GLY 151.A O no hydrogen 2.597 N/A ASN 159.A ND2 MET 177.A O no hydrogen 3.004 N/A GLU 162.A N ALA 148.A O no hydrogen 3.042 N/A CYS 163.A N ARG 172.A O no hydrogen 2.728 N/A CYS 163.A SG LEU 146.A O no hydrogen 4.036 N/A TYR 164.A N LEU 146.A O no hydrogen 2.706 N/A TYR 164.A OH ASN 169.A OD1 no hydrogen 2.533 N/A TYR 165.A N GLU 170.A O no hydrogen 2.989 N/A ASN 169.A N TYR 165.A O no hydrogen 2.586 N/A TRP 171.A NE1 ALA 128.A O no hydrogen 2.912 N/A ARG 172.A N CYS 163.A O no hydrogen 2.885 N/A ILE 174.A N ALA 161.A O no hydrogen 2.907 N/A THR 175.A OG1 ALA 216.A O no hydrogen 2.819 N/A MET 177.A N ASN 159.A O no hydrogen 2.803 N/A ASN 178.A N GLU 209.A OE1 no hydrogen 2.707 N/A ASN 178.A ND2 GLU 209.A OE1 no hydrogen 2.407 N/A ASN 178.A ND2 TRP 218.A O no hydrogen 3.055 N/A THR 179.A N GLU 209.A OE2 no hydrogen 2.923 N/A ARG 181.A N LEU 158.A O no hydrogen 2.896 N/A ARG 181.A NE GLU 209.A OE2 no hydrogen 3.308 N/A ARG 181.A NH1 GLY 197.A O no hydrogen 2.913 N/A ARG 181.A NH1 SER 207.A O no hydrogen 2.871 N/A ARG 181.A NH2 SER 207.A OG no hydrogen 2.962 N/A ARG 181.A NH2 GLU 209.A OE2 no hydrogen 3.273 N/A SER 182.A N TYR 199.A O no hydrogen 2.862 N/A SER 182.A OG TYR 199.A O no hydrogen 3.264 N/A GLY 183.A N GLY 136.A O no hydrogen 2.822 N/A GLY 185.A N ALA 196.A O no hydrogen 2.906 N/A CYS 187.A N TYR 194.A O no hydrogen 3.032 N/A LEU 189.A N CYS 192.A O no hydrogen 2.990 N/A CYS 192.A N LEU 189.A O no hydrogen 3.067 N/A ILE 193.A N TYR 211.A O no hydrogen 3.125 N/A TYR 194.A N CYS 187.A O no hydrogen 2.674 N/A ALA 195.A N GLU 209.A O no hydrogen 2.735 N/A ALA 196.A N GLY 185.A O no hydrogen 2.797 N/A GLY 197.A N SER 207.A O no hydrogen 2.969 N/A GLY 198.A N ARG 228.A O no hydrogen 3.015 N/A TYR 199.A N SER 182.A O no hydrogen 2.727 N/A ASP 200.A N ASP 203.A O no hydrogen 3.250 N/A GLN 202.A N ASP 200.A OD1 no hydrogen 2.827 N/A ASP 203.A N ASP 200.A OD1 no hydrogen 2.831 N/A LEU 205.A N GLY 198.A O no hydrogen 2.898 N/A GLU 209.A N ALA 195.A O no hydrogen 2.872 N/A ARG 210.A N THR 219.A O no hydrogen 2.760 N/A ARG 210.A NH1 TYR 194.A OH no hydrogen 2.508 N/A TYR 211.A N ILE 193.A O no hydrogen 2.704 N/A ASP 212.A N THR 217.A O no hydrogen 2.848 N/A ALA 214.A N ASP 212.A OD1 no hydrogen 3.308 N/A THR 215.A N ASP 212.A OD2 no hydrogen 2.796 N/A THR 215.A OG1 ASP 212.A OD2 no hydrogen 2.876 N/A ALA 216.A N VAL 213.A O no hydrogen 3.018 N/A THR 217.A N ASP 212.A O no hydrogen 3.110 N/A THR 217.A OG1 THR 215.A O no hydrogen 2.963 N/A TRP 218.A NE1 THR 175.A O no hydrogen 3.038 N/A THR 219.A N ARG 210.A O no hydrogen 2.865 N/A VAL 221.A N VAL 208.A O no hydrogen 2.814 N/A ALA 222.A N ASP 263.A OD1 no hydrogen 2.934 N/A MET 224.A N ASN 206.A O no hydrogen 2.781 N/A LYS 225.A N GLU 256.A OE2 no hydrogen 2.692 N/A HIS 226.A N GLU 256.A OE1 no hydrogen 3.033 N/A ARG 227.A NH1 GLN 204.A O no hydrogen 3.156 N/A ARG 228.A N LEU 205.A O no hydrogen 3.142 N/A ARG 228.A NE HIS 226.A O no hydrogen 3.168 N/A ARG 228.A NH1 GLY 244.A O no hydrogen 2.679 N/A ARG 228.A NH1 SER 254.A O no hydrogen 3.189 N/A ARG 228.A NH2 SER 254.A OG no hydrogen 2.966 N/A ARG 228.A NH2 GLU 256.A OE1 no hydrogen 2.636 N/A SER 229.A N TYR 246.A O no hydrogen 2.705 N/A ALA 230.A N GLY 183.A O no hydrogen 2.865 N/A GLY 232.A N LEU 243.A O no hydrogen 2.958 N/A THR 234.A N TYR 241.A O no hydrogen 3.015 N/A HIS 236.A N ARG 239.A O no hydrogen 2.850 N/A ARG 239.A N HIS 236.A O no hydrogen 3.044 N/A ILE 240.A N TYR 258.A O no hydrogen 3.133 N/A TYR 241.A N THR 234.A O no hydrogen 2.846 N/A VAL 242.A N GLU 256.A O no hydrogen 2.796 N/A LEU 243.A N GLY 232.A O no hydrogen 2.713 N/A GLY 244.A N SER 254.A O no hydrogen 3.024 N/A GLY 245.A N ARG 275.A O no hydrogen 3.064 N/A TYR 246.A N SER 229.A O no hydrogen 2.750 N/A ASP 247.A N THR 250.A O no hydrogen 3.264 N/A HIS 249.A N ASP 247.A OD1 no hydrogen 3.202 N/A THR 250.A N ASP 247.A OD1 no hydrogen 2.770 N/A THR 250.A OG1 ASP 247.A OD1 no hydrogen 3.120 N/A THR 250.A OG1 ASP 247.A OD2 no hydrogen 3.400 N/A LEU 252.A N GLY 245.A O no hydrogen 2.778 N/A SER 254.A OG GLU 267.A OE1 no hydrogen 2.729 N/A VAL 255.A N THR 269.A O no hydrogen 3.010 N/A GLU 256.A N VAL 242.A O no hydrogen 3.040 N/A CYS 257.A N SER 266.A O no hydrogen 2.747 N/A CYS 257.A SG ILE 240.A O no hydrogen 3.746 N/A TYR 258.A N ILE 240.A O no hydrogen 2.743 N/A TYR 258.A OH ASP 263.A OD1 no hydrogen 2.347 N/A ASP 259.A N THR 264.A O no hydrogen 2.907 N/A ASP 261.A N ASP 259.A OD1 no hydrogen 3.388 N/A THR 262.A N ASP 259.A O no hydrogen 3.386 N/A THR 262.A OG1 ASP 259.A OD2 no hydrogen 3.386 N/A THR 262.A OG1 THR 264.A OG1 no hydrogen 2.505 N/A THR 264.A N ASP 259.A O no hydrogen 3.346 N/A THR 264.A OG1 THR 262.A OG1 no hydrogen 2.505 N/A TRP 265.A NE1 ALA 222.A O no hydrogen 2.632 N/A SER 266.A N CYS 257.A O no hydrogen 2.839 N/A VAL 268.A N VAL 255.A O no hydrogen 3.016 N/A ARG 270.A NH1 ASP 253.A OD1 no hydrogen 2.739 N/A MET 271.A N ASP 253.A O no hydrogen 2.779 N/A THR 272.A OG1 GLU 17.A OE1 no hydrogen 3.220 N/A THR 272.A OG1 GLU 17.A OE2 no hydrogen 2.496 N/A ARG 275.A N LEU 252.A O no hydrogen 3.035 N/A ARG 275.A NE SER 273.A O no hydrogen 2.953 N/A ARG 275.A NH1 GLU 17.A OE1 no hydrogen 2.832 N/A ARG 275.A NH2 GLU 17.A OE1 no hydrogen 2.929 N/A ARG 275.A NH2 THR 272.A OG1 no hydrogen 3.209 N/A ARG 275.A NH2 SER 273.A O no hydrogen 3.186 N/A ARG 275.A NH2 SER 273.A OG no hydrogen 3.181 N/A SER 276.A N TYR 8.A O no hydrogen 2.933 N/A GLY 277.A N ALA 230.A O no hydrogen 2.754 N/A GLY 279.A N ALA 5.A O no hydrogen 2.964 N/A ALA 281.A N TYR 3.A O no hydrogen 3.115 N/A THR 283.A N LEU 1.A O no hydrogen 3.303 N/A THR 283.A OG1 GLY 46.A O no hydrogen 2.897 N/A MET 284.A N THR 283.A OG1 no hydrogen 2.769 N/A SER 287.A OG MET 73.A O no hydrogen 3.484 N/A