Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7k2q_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 1.A N THR 283.A O no hydrogen 3.012 N/A ILE 2.A N TYR 19.A O no hydrogen 2.951 N/A TYR 3.A N ALA 281.A O no hydrogen 2.796 N/A TYR 3.A OH MET 284.A O no hydrogen 2.584 N/A THR 4.A N GLU 17.A O no hydrogen 2.820 N/A ALA 5.A N GLY 279.A O no hydrogen 2.848 N/A GLY 6.A N TYR 15.A O no hydrogen 2.899 N/A GLY 7.A N ARG 36.A O no hydrogen 2.850 N/A TYR 8.A N SER 276.A O no hydrogen 2.677 N/A PHE 9.A N GLN 11.A O no hydrogen 3.010 N/A SER 12.A N ASN 56.A O no hydrogen 2.933 N/A SER 12.A OG SER 37.A OG no hydrogen 3.236 N/A SER 12.A OG ARG 54.A O no hydrogen 2.958 N/A LEU 13.A N GLY 7.A O no hydrogen 2.925 N/A GLU 17.A N THR 4.A O no hydrogen 2.971 N/A ALA 18.A N LEU 27.A O no hydrogen 2.914 N/A TYR 19.A N ILE 2.A O no hydrogen 2.783 N/A ASN 20.A N THR 25.A O no hydrogen 3.050 N/A ASP 23.A N ASN 20.A OD1 no hydrogen 2.756 N/A GLY 24.A N ASN 20.A O no hydrogen 2.573 N/A LEU 27.A N ALA 18.A O no hydrogen 2.803 N/A ARG 28.A NH2 ASP 31.A OD1 no hydrogen 2.830 N/A ARG 28.A NH2 ASP 31.A OD2 no hydrogen 3.552 N/A LEU 29.A N LEU 16.A O no hydrogen 2.980 N/A ALA 30.A N ASN 75.A OD1 no hydrogen 3.341 N/A LEU 32.A N SER 14.A O no hydrogen 2.863 N/A ARG 36.A N LEU 13.A O no hydrogen 2.939 N/A ARG 36.A NE GLY 52.A O no hydrogen 3.101 N/A ARG 36.A NH2 ALA 50.A O no hydrogen 3.096 N/A ARG 36.A NH2 GLY 52.A O no hydrogen 3.093 N/A SER 37.A N ARG 54.A O no hydrogen 2.889 N/A SER 37.A OG SER 12.A OG no hydrogen 3.236 N/A SER 37.A OG ASN 56.A OD1 no hydrogen 3.435 N/A GLY 38.A N GLY 277.A O no hydrogen 3.019 N/A ALA 40.A N VAL 51.A O no hydrogen 2.939 N/A CYS 42.A N TYR 49.A O no hydrogen 2.985 N/A VAL 44.A N LEU 47.A O no hydrogen 2.990 N/A LEU 47.A N VAL 44.A O no hydrogen 2.884 N/A LEU 48.A N TYR 70.A O no hydrogen 3.000 N/A TYR 49.A N CYS 42.A O no hydrogen 2.812 N/A ALA 50.A N ASP 68.A O no hydrogen 2.837 N/A VAL 51.A N ALA 40.A O no hydrogen 2.857 N/A GLY 52.A N ALA 66.A O no hydrogen 3.044 N/A GLY 53.A N ARG 87.A O no hydrogen 2.881 N/A ARG 54.A N SER 37.A O no hydrogen 2.681 N/A ARG 54.A NE ASP 63.A OD1 no hydrogen 2.692 N/A ASN 55.A N THR 62.A O no hydrogen 2.846 N/A ASN 56.A N SER 12.A OG no hydrogen 2.875 N/A ASN 56.A ND2 ASN 61.A OD1 no hydrogen 2.718 N/A SER 57.A N GLY 60.A O no hydrogen 2.820 N/A SER 57.A OG ASN 55.A OD1 no hydrogen 2.802 N/A GLY 60.A N SER 57.A O no hydrogen 2.955 N/A THR 62.A N ASN 55.A O no hydrogen 3.008 N/A THR 62.A OG1 ASP 63.A O no hydrogen 3.051 N/A SER 64.A N GLY 53.A O no hydrogen 2.867 N/A ALA 66.A N SER 64.A OG no hydrogen 3.130 N/A ASP 68.A N ALA 50.A O no hydrogen 2.963 N/A CYS 69.A N SER 78.A O no hydrogen 2.836 N/A TYR 70.A N LEU 48.A O no hydrogen 2.793 N/A TYR 70.A OH ASN 75.A OD1 no hydrogen 2.292 N/A ASN 71.A N GLN 76.A O no hydrogen 2.903 N/A MET 73.A N ASN 71.A OD1 no hydrogen 2.934 N/A THR 74.A OG1 ASN 71.A O no hydrogen 3.516 N/A GLN 76.A N ASN 71.A O no hydrogen 3.092 N/A TRP 77.A NE1 ALA 30.A O no hydrogen 2.992 N/A SER 78.A N CYS 69.A O no hydrogen 2.830 N/A CYS 80.A N LEU 67.A O no hydrogen 2.837 N/A ALA 81.A N ASP 122.A OD1 no hydrogen 2.950 N/A MET 83.A N SER 65.A O no hydrogen 2.873 N/A SER 84.A N GLU 115.A OE1 no hydrogen 2.797 N/A SER 84.A N GLU 115.A OE2 no hydrogen 3.239 N/A SER 84.A OG GLU 115.A OE1 no hydrogen 3.475 N/A SER 84.A OG GLU 115.A OE2 no hydrogen 2.700 N/A ARG 87.A N SER 64.A O no hydrogen 3.009 N/A ARG 87.A NE GLU 115.A OE2 no hydrogen 3.240 N/A ARG 87.A NH1 GLY 103.A O no hydrogen 2.793 N/A ARG 87.A NH1 SER 113.A O no hydrogen 2.847 N/A ARG 87.A NH1 SER 113.A OG no hydrogen 3.333 N/A ARG 87.A NH2 SER 113.A OG no hydrogen 3.085 N/A ARG 87.A NH2 GLU 115.A OE2 no hydrogen 2.881 N/A ASN 88.A N SER 105.A O no hydrogen 2.719 N/A ILE 90.A N GLY 38.A O no hydrogen 3.354 N/A GLY 91.A N VAL 102.A O no hydrogen 3.038 N/A GLY 93.A N TYR 100.A O no hydrogen 2.975 N/A ILE 95.A N HIS 98.A O no hydrogen 2.947 N/A HIS 98.A N ILE 95.A O no hydrogen 2.886 N/A ILE 99.A N TYR 117.A O no hydrogen 2.991 N/A TYR 100.A N GLY 93.A O no hydrogen 2.794 N/A ALA 101.A N GLU 115.A O no hydrogen 2.845 N/A VAL 102.A N GLY 91.A O no hydrogen 2.813 N/A GLY 103.A N SER 113.A O no hydrogen 3.303 N/A GLY 104.A N ARG 134.A O no hydrogen 2.963 N/A SER 105.A N ASN 88.A O no hydrogen 2.781 N/A HIS 106.A N ILE 109.A O no hydrogen 2.828 N/A GLY 107.A N ASP 63.A OD2 no hydrogen 2.585 N/A ILE 109.A N HIS 106.A O no hydrogen 2.912 N/A HIS 111.A N GLY 104.A O no hydrogen 2.885 N/A HIS 111.A NE2 PRO 86.A O no hydrogen 2.937 N/A GLU 115.A N ALA 101.A O no hydrogen 2.983 N/A ARG 116.A N HIS 125.A O no hydrogen 2.849 N/A TYR 117.A N ILE 99.A O no hydrogen 2.785 N/A TYR 117.A OH ASP 122.A OD1 no hydrogen 2.772 N/A GLU 118.A N GLU 123.A O no hydrogen 2.914 N/A ARG 121.A N GLU 118.A O no hydrogen 3.163 N/A ARG 121.A NE GLU 123.A OE2 no hydrogen 3.516 N/A TRP 124.A NE1 ALA 81.A O no hydrogen 2.863 N/A HIS 125.A N ARG 116.A O no hydrogen 2.872 N/A HIS 125.A NE2 GLU 123.A OE2 no hydrogen 3.018 N/A VAL 127.A N VAL 114.A O no hydrogen 2.905 N/A ALA 128.A N ASN 169.A OD1 no hydrogen 3.056 N/A MET 130.A N ASN 112.A O no hydrogen 2.754 N/A LEU 131.A N GLU 162.A OE2 no hydrogen 2.722 N/A THR 132.A OG1 GLU 162.A OE1 no hydrogen 2.887 N/A ARG 133.A NH1 HIS 110.A O no hydrogen 2.918 N/A ARG 134.A N HIS 111.A O no hydrogen 3.054 N/A ARG 134.A NE GLU 162.A OE1 no hydrogen 3.086 N/A ARG 134.A NH1 GLY 150.A O no hydrogen 2.891 N/A ARG 134.A NH1 SER 160.A O no hydrogen 3.004 N/A ARG 134.A NH1 SER 160.A OG no hydrogen 3.351 N/A ARG 134.A NH2 SER 160.A OG no hydrogen 3.293 N/A ARG 134.A NH2 GLU 162.A OE1 no hydrogen 2.906 N/A ILE 135.A N PHE 152.A O no hydrogen 2.913 N/A GLY 136.A N ARG 89.A O no hydrogen 3.082 N/A GLY 138.A N VAL 149.A O no hydrogen 2.927 N/A ALA 140.A N TYR 147.A O no hydrogen 2.968 N/A LEU 142.A N LEU 145.A O no hydrogen 2.956 N/A LEU 145.A N LEU 142.A O no hydrogen 2.905 N/A LEU 146.A N TYR 164.A O no hydrogen 3.080 N/A TYR 147.A N ALA 140.A O no hydrogen 2.800 N/A ALA 148.A N GLU 162.A O no hydrogen 2.939 N/A VAL 149.A N GLY 138.A O no hydrogen 2.809 N/A GLY 150.A N SER 160.A O no hydrogen 2.977 N/A GLY 151.A N ARG 181.A O no hydrogen 2.787 N/A ASP 153.A N ASN 156.A O no hydrogen 3.028 N/A THR 155.A N ASP 153.A OD1 no hydrogen 2.745 N/A ASN 156.A N ASP 153.A OD1 no hydrogen 2.663 N/A LEU 158.A N GLY 151.A O no hydrogen 3.048 N/A GLU 162.A N ALA 148.A O no hydrogen 2.928 N/A CYS 163.A N ARG 172.A O no hydrogen 2.873 N/A CYS 163.A SG LEU 146.A O no hydrogen 3.888 N/A TYR 164.A N LEU 146.A O no hydrogen 2.728 N/A TYR 164.A OH ASN 169.A OD1 no hydrogen 2.728 N/A TYR 165.A N GLU 170.A O no hydrogen 2.986 N/A ARG 168.A N TYR 165.A O no hydrogen 3.253 N/A TRP 171.A NE1 ALA 128.A O no hydrogen 3.004 N/A ARG 172.A N CYS 163.A O no hydrogen 2.868 N/A ILE 174.A N ALA 161.A O no hydrogen 3.020 N/A THR 175.A OG1 ALA 216.A O no hydrogen 2.996 N/A MET 177.A N ASN 159.A O no hydrogen 2.755 N/A ASN 178.A N GLU 209.A OE1 no hydrogen 2.827 N/A ASN 178.A ND2 GLU 209.A OE1 no hydrogen 2.932 N/A ASN 178.A ND2 TRP 218.A O no hydrogen 3.196 N/A THR 179.A N GLU 209.A OE2 no hydrogen 3.139 N/A THR 179.A OG1 GLU 209.A OE2 no hydrogen 3.384 N/A ARG 181.A N LEU 158.A O no hydrogen 3.025 N/A ARG 181.A NE GLU 209.A OE2 no hydrogen 3.096 N/A ARG 181.A NH1 GLY 197.A O no hydrogen 2.852 N/A ARG 181.A NH1 SER 207.A O no hydrogen 3.000 N/A ARG 181.A NH1 SER 207.A OG no hydrogen 3.045 N/A ARG 181.A NH2 SER 207.A OG no hydrogen 2.693 N/A ARG 181.A NH2 GLU 209.A OE2 no hydrogen 3.030 N/A SER 182.A N TYR 199.A O no hydrogen 2.942 N/A GLY 183.A N GLY 136.A O no hydrogen 2.806 N/A GLY 185.A N ALA 196.A O no hydrogen 2.914 N/A CYS 187.A N TYR 194.A O no hydrogen 2.939 N/A LEU 189.A N CYS 192.A O no hydrogen 3.092 N/A CYS 192.A N LEU 189.A O no hydrogen 2.968 N/A ILE 193.A N TYR 211.A O no hydrogen 3.015 N/A TYR 194.A N CYS 187.A O no hydrogen 2.662 N/A ALA 195.A N GLU 209.A O no hydrogen 2.860 N/A ALA 196.A N GLY 185.A O no hydrogen 2.864 N/A GLY 197.A N SER 207.A O no hydrogen 2.895 N/A GLY 198.A N ARG 228.A O no hydrogen 3.014 N/A TYR 199.A N SER 182.A O no hydrogen 2.807 N/A ASP 200.A N ASP 203.A O no hydrogen 3.269 N/A GLN 202.A N ASP 200.A OD1 no hydrogen 2.847 N/A ASP 203.A N ASP 200.A OD1 no hydrogen 2.846 N/A LEU 205.A N GLY 198.A O no hydrogen 2.918 N/A GLU 209.A N ALA 195.A O no hydrogen 2.922 N/A ARG 210.A N THR 219.A O no hydrogen 2.878 N/A ARG 210.A NE TYR 194.A OH no hydrogen 2.870 N/A TYR 211.A N ILE 193.A O no hydrogen 2.774 N/A ASP 212.A N THR 217.A O no hydrogen 2.913 N/A THR 215.A N ASP 212.A OD2 no hydrogen 3.108 N/A THR 215.A OG1 ASP 212.A OD2 no hydrogen 2.782 N/A ALA 216.A N VAL 213.A O no hydrogen 3.128 N/A THR 217.A N ASP 212.A O no hydrogen 3.054 N/A THR 217.A OG1 THR 215.A O no hydrogen 2.786 N/A TRP 218.A NE1 THR 175.A O no hydrogen 2.896 N/A THR 219.A N ARG 210.A O no hydrogen 2.908 N/A VAL 221.A N VAL 208.A O no hydrogen 2.854 N/A ALA 222.A N ASP 263.A OD2 no hydrogen 2.968 N/A MET 224.A N ASN 206.A O no hydrogen 2.847 N/A LYS 225.A N GLU 256.A OE2 no hydrogen 2.711 N/A LYS 225.A NZ TRP 265.A O no hydrogen 3.281 N/A HIS 226.A N GLU 256.A OE1 no hydrogen 2.902 N/A HIS 226.A NE2 GLU 267.A OE1 no hydrogen 2.896 N/A ARG 227.A NH1 GLN 204.A O no hydrogen 2.841 N/A ARG 228.A N LEU 205.A O no hydrogen 3.082 N/A ARG 228.A NE HIS 226.A O no hydrogen 3.121 N/A ARG 228.A NH1 GLY 244.A O no hydrogen 2.924 N/A ARG 228.A NH1 SER 254.A O no hydrogen 3.191 N/A ARG 228.A NH2 SER 254.A OG no hydrogen 2.710 N/A ARG 228.A NH2 GLU 256.A OE1 no hydrogen 2.870 N/A SER 229.A N TYR 246.A O no hydrogen 2.760 N/A ALA 230.A N GLY 183.A O no hydrogen 2.826 N/A GLY 232.A N LEU 243.A O no hydrogen 2.924 N/A THR 234.A N TYR 241.A O no hydrogen 2.937 N/A HIS 236.A N ARG 239.A O no hydrogen 2.923 N/A ARG 239.A N HIS 236.A O no hydrogen 2.945 N/A ILE 240.A N TYR 258.A O no hydrogen 3.025 N/A TYR 241.A N THR 234.A O no hydrogen 2.858 N/A VAL 242.A N GLU 256.A O no hydrogen 2.935 N/A LEU 243.A N GLY 232.A O no hydrogen 2.855 N/A GLY 244.A N SER 254.A O no hydrogen 3.044 N/A GLY 245.A N ARG 275.A O no hydrogen 2.881 N/A TYR 246.A N SER 229.A O no hydrogen 2.774 N/A ASP 247.A N THR 250.A O no hydrogen 3.212 N/A HIS 249.A N ASP 247.A OD1 no hydrogen 3.036 N/A THR 250.A N ASP 247.A OD1 no hydrogen 2.691 N/A LEU 252.A N GLY 245.A O no hydrogen 2.677 N/A SER 254.A OG GLU 267.A OE1 no hydrogen 3.432 N/A VAL 255.A N THR 269.A O no hydrogen 2.925 N/A GLU 256.A N VAL 242.A O no hydrogen 2.941 N/A CYS 257.A N SER 266.A O no hydrogen 2.716 N/A CYS 257.A SG ILE 240.A O no hydrogen 3.748 N/A TYR 258.A N ILE 240.A O no hydrogen 2.799 N/A TYR 258.A OH ASP 263.A OD2 no hydrogen 2.516 N/A ASP 259.A N THR 264.A O no hydrogen 3.034 N/A ASP 261.A N ASP 259.A OD1 no hydrogen 3.195 N/A THR 262.A OG1 ASP 259.A O no hydrogen 3.266 N/A THR 262.A OG1 ASP 259.A OD2 no hydrogen 2.911 N/A THR 262.A OG1 THR 264.A OG1 no hydrogen 2.588 N/A ASP 263.A N PRO 260.A O no hydrogen 3.232 N/A THR 264.A N ASP 259.A O no hydrogen 3.370 N/A THR 264.A OG1 THR 262.A OG1 no hydrogen 2.588 N/A TRP 265.A NE1 ALA 222.A O no hydrogen 2.785 N/A SER 266.A N CYS 257.A O no hydrogen 2.828 N/A SER 266.A OG GLU 267.A O no hydrogen 3.500 N/A VAL 268.A N VAL 255.A O no hydrogen 2.952 N/A THR 269.A OG1 ARG 270.A O no hydrogen 3.413 N/A ARG 270.A NH1 ASP 253.A OD1 no hydrogen 3.336 N/A MET 271.A N ASP 253.A O no hydrogen 2.775 N/A THR 272.A OG1 GLU 17.A OE1 no hydrogen 3.288 N/A THR 272.A OG1 GLU 17.A OE2 no hydrogen 2.614 N/A ARG 275.A N LEU 252.A O no hydrogen 3.014 N/A ARG 275.A NE SER 273.A O no hydrogen 2.993 N/A ARG 275.A NH1 GLU 17.A OE1 no hydrogen 2.737 N/A ARG 275.A NH2 GLU 17.A OE1 no hydrogen 2.938 N/A ARG 275.A NH2 THR 272.A OG1 no hydrogen 3.123 N/A ARG 275.A NH2 SER 273.A O no hydrogen 3.270 N/A ARG 275.A NH2 SER 273.A OG no hydrogen 2.900 N/A SER 276.A N TYR 8.A O no hydrogen 3.101 N/A GLY 277.A N ALA 230.A O no hydrogen 2.828 N/A GLY 279.A N ALA 5.A O no hydrogen 2.940 N/A ALA 281.A N TYR 3.A O no hydrogen 2.995 N/A THR 283.A N LEU 1.A O no hydrogen 3.382 N/A THR 283.A OG1 GLY 46.A O no hydrogen 3.137 N/A SER 287.A N PRO 72.A O no hydrogen 3.223 N/A