Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7k9x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 7.A N GLN 10.A OE1 no hydrogen 2.703 N/A THR 7.A OG1 GLU 9.A OE1 no hydrogen 3.101 N/A THR 7.A OG1 GLN 10.A OE1 no hydrogen 3.131 N/A GLU 9.A N GLU 9.A OE1 no hydrogen 2.821 N/A GLN 10.A N THR 7.A OG1 no hydrogen 3.242 N/A LYS 11.A N THR 7.A O no hydrogen 3.153 N/A LYS 12.A N PRO 8.A O no hydrogen 2.900 N/A LYS 12.A NZ ASP 16.A OD2 no hydrogen 3.070 N/A GLU 13.A N GLU 9.A O no hydrogen 2.936 N/A LEU 14.A N GLN 10.A O no hydrogen 3.040 N/A SER 15.A N LYS 11.A O no hydrogen 2.934 N/A SER 15.A OG LYS 11.A O no hydrogen 2.507 N/A SER 15.A OG LYS 12.A O no hydrogen 2.913 N/A ASP 16.A N LYS 12.A O no hydrogen 2.964 N/A ILE 17.A N GLU 13.A O no hydrogen 2.928 N/A ALA 18.A N LEU 14.A O no hydrogen 2.979 N/A HIS 19.A N SER 15.A O no hydrogen 2.895 N/A ARG 20.A N ASP 16.A O no hydrogen 2.910 N/A ILE 21.A N ILE 17.A O no hydrogen 2.917 N/A VAL 22.A N ALA 18.A O no hydrogen 3.313 N/A LYS 26.A N ALA 23.A O no hydrogen 2.918 N/A GLY 27.A N CYS 71.A O no hydrogen 2.820 N/A ILE 28.A N PHE 298.A O no hydrogen 2.874 N/A LEU 29.A N GLY 74.A O no hydrogen 3.235 N/A ASP 32.A N ASP 32.A OD1 no hydrogen 2.431 N/A ILE 38.A N SER 34.A O no hydrogen 2.889 N/A ALA 39.A N THR 35.A O no hydrogen 2.842 N/A LYS 40.A N GLY 36.A O no hydrogen 2.945 N/A ARG 41.A N SER 37.A O no hydrogen 2.956 N/A LEU 42.A N ILE 38.A O no hydrogen 2.849 N/A GLN 43.A N ALA 39.A O no hydrogen 2.882 N/A SER 44.A N LYS 40.A O no hydrogen 2.919 N/A SER 44.A OG LYS 40.A O no hydrogen 3.292 N/A SER 44.A OG ARG 41.A O no hydrogen 2.489 N/A ILE 45.A N ARG 41.A O no hydrogen 3.163 N/A GLY 46.A N LEU 42.A O no hydrogen 2.909 N/A THR 47.A N LEU 42.A O no hydrogen 2.931 N/A THR 47.A OG1 LEU 42.A O no hydrogen 3.549 N/A ASN 53.A N THR 50.A OG1 no hydrogen 3.276 N/A ASN 53.A ND2 GLU 48.A O no hydrogen 2.368 N/A ARG 54.A N THR 50.A O no hydrogen 3.278 N/A ARG 55.A N GLU 51.A O no hydrogen 2.923 N/A ARG 55.A NH1 LYS 85.A O no hydrogen 3.100 N/A ARG 55.A NH1 ASP 87.A OD2 no hydrogen 2.939 N/A ARG 55.A NH2 ASP 87.A OD2 no hydrogen 3.144 N/A PHE 56.A N GLU 52.A O no hydrogen 2.863 N/A TYR 57.A N ASN 53.A O no hydrogen 2.848 N/A TYR 57.A OH GLN 305.A O no hydrogen 3.376 N/A ARG 58.A N ARG 54.A O no hydrogen 2.971 N/A ARG 58.A NE ALA 31.A O no hydrogen 3.173 N/A ARG 58.A NH2 ALA 31.A O no hydrogen 3.556 N/A GLN 59.A N ARG 55.A O no hydrogen 2.846 N/A GLN 59.A NE2 ASP 87.A OD2 no hydrogen 2.385 N/A LEU 60.A N PHE 56.A O no hydrogen 2.893 N/A LEU 61.A N TYR 57.A O no hydrogen 2.925 N/A LEU 62.A N ARG 58.A O no hydrogen 2.884 N/A THR 63.A N GLN 59.A O no hydrogen 3.143 N/A THR 63.A OG1 THR 63.A O no hydrogen 2.259 N/A ASP 66.A N ASP 65.A OD1 no hydrogen 2.717 N/A ARG 67.A NE ASP 65.A OD2 no hydrogen 2.397 N/A ARG 67.A NH1 GLU 324.A OE2 no hydrogen 3.536 N/A ARG 67.A NH2 GLU 324.A OE1 no hydrogen 3.059 N/A ARG 67.A NH2 GLU 324.A OE2 no hydrogen 3.522 N/A VAL 68.A N ASP 65.A O no hydrogen 3.329 N/A ASN 69.A N ASP 66.A O no hydrogen 3.127 N/A CYS 71.A N VAL 68.A O no hydrogen 3.015 N/A CYS 71.A SG ALA 330.A O no hydrogen 3.187 N/A ILE 72.A N VAL 68.A O no hydrogen 3.204 N/A GLY 73.A N GLY 27.A O no hydrogen 2.900 N/A VAL 75.A N VAL 102.A O no hydrogen 2.850 N/A ILE 76.A N LEU 29.A O no hydrogen 2.957 N/A LEU 77.A N GLY 104.A O no hydrogen 3.199 N/A THR 81.A N PHE 78.A O no hydrogen 3.316 N/A TYR 83.A N GLU 80.A O no hydrogen 3.078 N/A TYR 83.A OH ASP 139.A OD2 no hydrogen 2.591 N/A GLN 84.A N THR 81.A O no hydrogen 3.363 N/A GLN 84.A NE2 GLU 51.A OE2 no hydrogen 2.450 N/A ALA 86.A N ARG 90.A O no hydrogen 2.786 N/A GLY 89.A N ALA 86.A O no hydrogen 2.984 N/A PHE 92.A N GLN 84.A O no hydrogen 3.457 N/A VAL 95.A N PRO 91.A O no hydrogen 2.949 N/A ILE 96.A N PHE 92.A O no hydrogen 2.928 N/A LYS 97.A N PRO 93.A O no hydrogen 2.913 N/A LYS 97.A NZ GLY 140.A O no hydrogen 3.079 N/A SER 98.A N GLN 94.A O no hydrogen 2.867 N/A SER 98.A OG GLN 94.A O no hydrogen 2.822 N/A SER 98.A OG VAL 95.A O no hydrogen 2.546 N/A LYS 99.A NZ LEU 62.A O no hydrogen 2.687 N/A GLY 100.A N LYS 97.A O no hydrogen 3.459 N/A GLY 101.A N ILE 96.A O no hydrogen 2.822 N/A GLY 104.A N VAL 75.A O no hydrogen 2.848 N/A LYS 106.A N LEU 77.A O no hydrogen 3.089 N/A LYS 106.A NZ ASP 108.A OD1 no hydrogen 2.847 N/A VAL 107.A N LYS 145.A O no hydrogen 3.127 N/A LYS 109.A N GLN 124.A O no hydrogen 2.757 N/A VAL 112.A N THR 122.A O no hydrogen 2.892 N/A LEU 114.A N GLU 120.A O no hydrogen 2.783 N/A THR 117.A OG1 LEU 114.A O no hydrogen 3.216 N/A THR 117.A OG1 GLU 120.A O no hydrogen 3.286 N/A GLU 120.A N THR 117.A OG1 no hydrogen 3.023 N/A THR 122.A N VAL 112.A O no hydrogen 2.869 N/A THR 122.A OG1 THR 123.A O no hydrogen 3.322 N/A THR 122.A OG1 ASN 165.A OD1 no hydrogen 3.502 N/A THR 123.A OG1 ARG 147.A O no hydrogen 3.391 N/A GLN 124.A N GLY 110.A O no hydrogen 2.908 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.707 N/A ARG 132.A N GLY 128.A O no hydrogen 3.009 N/A ARG 132.A NH1 ASP 127.A O no hydrogen 3.507 N/A ARG 132.A NH2 VAL 107.A O no hydrogen 2.926 N/A CYS 133.A N LEU 129.A O no hydrogen 2.897 N/A CYS 133.A SG LEU 129.A O no hydrogen 3.181 N/A ALA 134.A N SER 130.A O no hydrogen 2.916 N/A GLN 135.A N GLU 131.A O no hydrogen 2.895 N/A GLN 135.A NE2 ASP 139.A OD2 no hydrogen 2.979 N/A TYR 136.A N ARG 132.A O no hydrogen 2.861 N/A LYS 137.A N CYS 133.A O no hydrogen 2.850 N/A LYS 137.A NZ ASP 142.A OD1 no hydrogen 2.890 N/A LYS 138.A N ALA 134.A O no hydrogen 2.954 N/A LYS 138.A NZ GLN 135.A OE1 no hydrogen 2.499 N/A ASP 139.A N GLN 135.A O no hydrogen 3.130 N/A ASP 139.A N TYR 136.A O no hydrogen 3.179 N/A ALA 141.A N TYR 136.A O no hydrogen 2.792 N/A ASP 142.A N VAL 103.A O no hydrogen 2.893 N/A PHE 143.A N VAL 103.A O no hydrogen 3.474 N/A ALA 144.A N VAL 182.A O no hydrogen 3.152 N/A LYS 145.A NZ GLU 186.A OE1 no hydrogen 3.198 N/A ARG 147.A N ASP 108.A OD2 no hydrogen 3.374 N/A CYS 148.A N GLU 186.A O no hydrogen 3.419 N/A CYS 148.A SG GLU 186.A O no hydrogen 3.347 N/A LEU 150.A N GLU 188.A O no hydrogen 3.106 N/A LYS 151.A N GLU 120.A OE2 no hydrogen 3.471 N/A LYS 151.A NZ ASN 118.A O no hydrogen 2.960 N/A GLY 153.A N THR 156.A O no hydrogen 3.117 N/A THR 156.A OG1 LYS 151.A O no hydrogen 2.765 N/A ILE 162.A N SER 158.A O no hydrogen 3.408 N/A MET 163.A N ALA 159.A O no hydrogen 2.930 N/A GLU 164.A N LEU 160.A O no hydrogen 2.941 N/A ASN 165.A N ALA 161.A O no hydrogen 2.959 N/A ASN 165.A ND2 THR 121.A O no hydrogen 3.653 N/A ALA 166.A N ILE 162.A O no hydrogen 2.948 N/A ASN 167.A N MET 163.A O no hydrogen 2.946 N/A VAL 168.A N GLU 164.A O no hydrogen 2.956 N/A LEU 169.A N ASN 165.A O no hydrogen 2.963 N/A ALA 170.A N ALA 166.A O no hydrogen 2.983 N/A ARG 171.A N ASN 167.A O no hydrogen 2.971 N/A TYR 172.A N VAL 168.A O no hydrogen 2.950 N/A ALA 173.A N LEU 169.A O no hydrogen 2.952 N/A SER 174.A N ALA 170.A O no hydrogen 2.945 N/A SER 174.A OG ARG 171.A O no hydrogen 2.761 N/A ILE 175.A N ARG 171.A O no hydrogen 3.062 N/A CYS 176.A N TYR 172.A O no hydrogen 2.957 N/A CYS 176.A SG TYR 172.A O no hydrogen 3.589 N/A GLN 177.A N ALA 173.A O no hydrogen 2.899 N/A GLN 177.A NE2 TYR 221.A O no hydrogen 2.836 N/A GLN 177.A NE2 GLY 224.A O no hydrogen 2.624 N/A GLN 178.A N SER 174.A O no hydrogen 2.966 N/A GLN 178.A NE2 ALA 5.A O no hydrogen 3.193 N/A ASN 179.A N CYS 176.A O no hydrogen 3.325 N/A ASN 179.A ND2 ILE 175.A O no hydrogen 2.682 N/A ILE 181.A N CYS 176.A O no hydrogen 2.993 N/A VAL 182.A N ASP 142.A O no hydrogen 3.017 N/A VAL 185.A N LEU 226.A O no hydrogen 2.929 N/A GLU 188.A N CYS 148.A O no hydrogen 3.237 N/A LEU 190.A N LEU 150.A O no hydrogen 2.520 N/A HIS 195.A NE2 ASP 192.A O no hydrogen 3.114 N/A ARG 199.A N ASP 196.A OD1 no hydrogen 2.888 N/A ARG 199.A NH2 GLU 154.A O no hydrogen 2.971 N/A CYS 200.A SG THR 233.A O no hydrogen 3.845 N/A GLN 201.A N LEU 197.A O no hydrogen 2.922 N/A TYR 202.A N LYS 198.A O no hydrogen 2.923 N/A VAL 203.A N ARG 199.A O no hydrogen 2.981 N/A THR 204.A N CYS 200.A O no hydrogen 2.963 N/A THR 204.A OG1 CYS 200.A O no hydrogen 2.410 N/A GLU 205.A N GLN 201.A O no hydrogen 2.999 N/A LYS 206.A N TYR 202.A O no hydrogen 3.081 N/A VAL 207.A N VAL 203.A O no hydrogen 2.943 N/A LEU 208.A N THR 204.A O no hydrogen 2.969 N/A ALA 209.A N GLU 205.A O no hydrogen 2.958 N/A ALA 210.A N LYS 206.A O no hydrogen 3.027 N/A VAL 211.A N VAL 207.A O no hydrogen 2.966 N/A TYR 212.A N LEU 208.A O no hydrogen 2.994 N/A LYS 213.A N ALA 209.A O no hydrogen 2.952 N/A ALA 214.A N ALA 210.A O no hydrogen 3.007 N/A LEU 215.A N VAL 211.A O no hydrogen 2.896 N/A SER 216.A N TYR 212.A O no hydrogen 2.960 N/A ASP 217.A N LYS 213.A O no hydrogen 2.957 N/A HIS 218.A N ALA 214.A O no hydrogen 3.189 N/A HIS 218.A NE2 ASN 167.A OD1 no hydrogen 2.964 N/A ILE 220.A N LEU 215.A O no hydrogen 3.246 N/A TYR 221.A N GLN 177.A OE1 no hydrogen 2.951 N/A GLU 223.A N GLU 223.A OE1 no hydrogen 2.728 N/A GLY 224.A N TYR 221.A O no hydrogen 3.040 N/A THR 225.A OG1 TYR 221.A O no hydrogen 3.497 N/A LEU 226.A N PRO 183.A O no hydrogen 3.015 N/A LEU 227.A N GLY 265.A O no hydrogen 3.235 N/A LYS 228.A N VAL 185.A O no hydrogen 2.621 N/A LYS 228.A NZ SER 299.A OG no hydrogen 2.576 N/A THR 233.A OG1 MET 231.A O no hydrogen 2.899 N/A GLY 235.A N HIS 195.A O no hydrogen 3.065 N/A ALA 237.A N GLY 193.A O no hydrogen 2.650 N/A CYS 238.A N GLY 235.A O no hydrogen 3.198 N/A CYS 238.A SG GLN 240.A OE1 no hydrogen 4.050 N/A SER 243.A OG GLU 245.A OE1 no hydrogen 2.999 N/A GLU 245.A N GLU 245.A OE1 no hydrogen 2.779 N/A GLU 246.A N SER 243.A OG no hydrogen 3.366 N/A ILE 247.A N SER 243.A O no hydrogen 3.454 N/A ALA 248.A N HIS 244.A O no hydrogen 2.895 N/A MET 249.A N GLU 245.A O no hydrogen 2.897 N/A ALA 250.A N GLU 246.A O no hydrogen 2.926 N/A THR 251.A N ILE 247.A O no hydrogen 2.903 N/A THR 251.A OG1 ILE 247.A O no hydrogen 2.977 N/A THR 251.A OG1 ALA 248.A O no hydrogen 2.612 N/A VAL 252.A N ALA 248.A O no hydrogen 3.011 N/A THR 253.A N MET 249.A O no hydrogen 2.911 N/A THR 253.A OG1 MET 249.A O no hydrogen 2.254 N/A ALA 254.A N ALA 250.A O no hydrogen 2.888 N/A LEU 255.A N THR 251.A O no hydrogen 2.918 N/A ARG 256.A N VAL 252.A O no hydrogen 2.886 N/A ARG 256.A NE LEU 291.A O no hydrogen 2.739 N/A ARG 257.A N THR 253.A O no hydrogen 3.045 N/A THR 258.A N LEU 255.A O no hydrogen 2.844 N/A THR 258.A OG1 GLU 205.A OE2 no hydrogen 3.056 N/A THR 258.A OG1 ALA 254.A O no hydrogen 3.326 N/A VAL 259.A N LEU 255.A O no hydrogen 2.874 N/A VAL 263.A N PRO 260.A O no hydrogen 3.159 N/A VAL 266.A N ALA 295.A O no hydrogen 2.746 N/A THR 267.A N LEU 227.A O no hydrogen 2.930 N/A THR 267.A OG1 LEU 227.A O no hydrogen 3.492 N/A PHE 268.A N THR 297.A O no hydrogen 3.004 N/A LEU 269.A N PRO 229.A O no hydrogen 3.090 N/A SER 274.A N GLU 277.A OE1 no hydrogen 3.234 N/A GLU 275.A N GLU 275.A OE1 no hydrogen 2.618 N/A GLU 276.A N SER 274.A OG no hydrogen 2.920 N/A GLU 277.A N SER 274.A OG no hydrogen 2.732 N/A SER 279.A OG GLU 276.A O no hydrogen 3.067 N/A SER 279.A OG GLU 276.A OE2 no hydrogen 3.521 N/A ILE 280.A N GLU 276.A O no hydrogen 2.951 N/A ASN 281.A N GLU 277.A O no hydrogen 2.879 N/A LEU 282.A N ALA 278.A O no hydrogen 2.913 N/A ASN 283.A N SER 279.A O no hydrogen 2.929 N/A ASN 283.A ND2 TYR 341.A O no hydrogen 2.657 N/A ALA 284.A N ILE 280.A O no hydrogen 2.937 N/A ILE 285.A N ASN 281.A O no hydrogen 2.868 N/A ASN 286.A N LEU 282.A O no hydrogen 2.935 N/A ASN 286.A ND2 LEU 282.A O no hydrogen 2.781 N/A LYS 287.A N ALA 284.A O no hydrogen 2.981 N/A CYS 288.A N ILE 285.A O no hydrogen 3.262 N/A LEU 290.A N CYS 288.A O no hydrogen 2.904 N/A THR 297.A N VAL 266.A O no hydrogen 2.923 N/A THR 297.A OG1 LYS 26.A O no hydrogen 2.616 N/A PHE 298.A N THR 297.A OG1 no hydrogen 2.587 N/A SER 299.A N PHE 268.A O no hydrogen 2.989 N/A TYR 300.A N ILE 28.A O no hydrogen 3.290 N/A TYR 300.A OH ALA 278.A O no hydrogen 3.201 N/A GLN 305.A N ARG 302.A O no hydrogen 3.179 N/A GLN 305.A NE2 GLU 33.A OE1 no hydrogen 2.760 N/A ALA 306.A N ARG 302.A O no hydrogen 2.899 N/A SER 307.A OG GLU 325.A OE2 no hydrogen 3.090 N/A LEU 309.A N GLN 305.A O no hydrogen 2.859 N/A LYS 310.A N ALA 306.A O no hydrogen 2.913 N/A ALA 311.A N SER 307.A O no hydrogen 2.878 N/A TRP 312.A N ALA 308.A O no hydrogen 2.925 N/A GLY 313.A N LEU 309.A O no hydrogen 3.067 N/A LYS 315.A N TRP 312.A O no hydrogen 3.512 N/A GLU 317.A N GLU 317.A OE1 no hydrogen 2.803 N/A LEU 319.A N LYS 316.A O no hydrogen 2.928 N/A ALA 322.A N ASN 318.A O no hydrogen 3.210 N/A GLN 323.A N LEU 319.A O no hydrogen 2.613 N/A GLN 323.A NE2 LEU 60.A O no hydrogen 2.574 N/A GLU 324.A N LYS 320.A O no hydrogen 2.588 N/A GLU 325.A N ALA 321.A O no hydrogen 2.866 N/A TYR 326.A N ALA 322.A O no hydrogen 3.060 N/A VAL 327.A N GLN 323.A O no hydrogen 3.042 N/A LYS 328.A N GLU 324.A O no hydrogen 3.111 N/A ARG 329.A N GLU 325.A O no hydrogen 3.394 N/A ARG 329.A NH1 GLU 276.A OE1 no hydrogen 2.670 N/A ALA 330.A N TYR 326.A O no hydrogen 3.069 N/A LEU 331.A N VAL 327.A O no hydrogen 2.787 N/A ALA 332.A N LYS 328.A O no hydrogen 2.952 N/A ASN 333.A N ARG 329.A O no hydrogen 2.706 N/A SER 334.A N ALA 330.A O no hydrogen 2.775 N/A SER 334.A OG LEU 331.A O no hydrogen 2.297 N/A LEU 335.A N LEU 331.A O no hydrogen 3.079 N/A ALA 336.A N ALA 332.A O no hydrogen 2.847 N/A CYS 337.A N ASN 333.A O no hydrogen 2.897 N/A CYS 337.A N SER 334.A O no hydrogen 3.012 N/A CYS 337.A SG LYS 26.A O no hydrogen 3.858 N/A CYS 337.A SG LEU 296.A O no hydrogen 3.457 N/A GLN 338.A N LEU 335.A O no hydrogen 2.990 N/A TYR 341.A OH GLU 276.A OE2 no hydrogen 2.284 N/A THR 342.A OG1 TYR 341.A O no hydrogen 3.048 N/A