Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7klx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N GLU 1.A O no hydrogen 3.104 N/A GLN 6.A N LYS 2.A O no hydrogen 3.046 N/A ILE 7.A N GLU 3.A O no hydrogen 3.070 N/A ASP 8.A N PHE 4.A O no hydrogen 2.892 N/A LYS 9.A N GLU 5.A O no hydrogen 2.909 N/A SER 10.A N GLN 6.A O no hydrogen 3.189 N/A SER 10.A OG GLN 6.A O no hydrogen 2.801 N/A SER 10.A OG SER 12.A OG no hydrogen 2.498 N/A SER 12.A N ILE 7.A O no hydrogen 2.991 N/A SER 12.A OG SER 10.A OG no hydrogen 2.498 N/A TRP 13.A NE1 ASP 8.A OD1 no hydrogen 2.808 N/A ILE 16.A N SER 12.A O no hydrogen 2.885 N/A TYR 17.A N TRP 13.A O no hydrogen 2.918 N/A TYR 17.A OH ILE 258.A O no hydrogen 2.742 N/A GLN 18.A N ALA 14.A O no hydrogen 2.859 N/A ASP 19.A N ALA 15.A O no hydrogen 3.011 N/A ILE 20.A N ILE 16.A O no hydrogen 3.015 N/A ARG 21.A N TYR 17.A O no hydrogen 2.916 N/A HIS 22.A N GLN 18.A O no hydrogen 2.841 N/A GLU 23.A N ASP 19.A O no hydrogen 3.004 N/A CYS 29.A SG PHE 27.A O no hydrogen 3.819 N/A CYS 29.A SG SER 47.A O no hydrogen 3.897 N/A CYS 29.A SG PRO 48.A O no hydrogen 3.283 N/A ARG 30.A N ASP 50.A OD2 no hydrogen 2.874 N/A VAL 31.A N ASP 50.A OD1 no hydrogen 3.030 N/A LYS 33.A N CYS 29.A O no hydrogen 3.238 N/A LYS 33.A N ARG 30.A O no hydrogen 3.241 N/A LEU 34.A N VAL 31.A O no hydrogen 3.081 N/A ASN 37.A N LEU 34.A O no hydrogen 2.871 N/A ASN 37.A ND2 VAL 31.A O no hydrogen 2.921 N/A LYS 38.A N PRO 35.A O no hydrogen 3.158 N/A ARG 40.A N ASN 37.A O no hydrogen 2.951 N/A ARG 40.A NH1 TYR 63.A O no hydrogen 2.863 N/A ASN 41.A N LYS 38.A O no hydrogen 3.503 N/A ASN 41.A ND2 ALA 32.A O no hydrogen 2.920 N/A ARG 42.A N GLN 82.A OE1 no hydrogen 2.851 N/A ARG 42.A NE GLY 83.A O no hydrogen 2.908 N/A ARG 42.A NH2 GLY 83.A O no hydrogen 3.226 N/A ARG 42.A NH2 PRO 84.A O no hydrogen 2.800 N/A ASP 45.A N ARG 42.A O no hydrogen 3.073 N/A ASP 50.A N PRO 28.A O no hydrogen 2.876 N/A HIS 51.A NE2 LYS 252.A O no hydrogen 2.847 N/A SER 52.A OG PHE 253.A O no hydrogen 2.592 N/A ARG 53.A NH1 ASP 62.A OD1 no hydrogen 2.995 N/A ARG 53.A NH2 ASP 62.A OD1 no hydrogen 3.099 N/A ARG 53.A NH2 ASP 62.A OD2 no hydrogen 3.197 N/A ILE 54.A N ALA 66.A O no hydrogen 3.125 N/A LEU 56.A N ASP 62.A O no hydrogen 2.881 N/A HIS 57.A N GLU 98.A OE1 no hydrogen 2.825 N/A ASN 61.A ND2 ASN 37.A OD1 no hydrogen 2.857 N/A TYR 63.A N ASN 61.A OD1 no hydrogen 3.045 N/A TYR 63.A OH ASN 41.A OD1 no hydrogen 2.620 N/A ASN 65.A ND2 ASN 41.A OD1 no hydrogen 3.223 N/A ASN 65.A ND2 VAL 46.A O no hydrogen 2.838 N/A SER 67.A N LEU 80.A O no hydrogen 2.854 N/A LEU 68.A N SER 52.A O no hydrogen 2.797 N/A ILE 69.A N.A TYR 78.A O no hydrogen 2.814 N/A ILE 69.A N.B TYR 78.A O no hydrogen 2.819 N/A MET 71.A N ARG 76.A O no hydrogen 2.826 N/A GLU 73.A N GLU 72.A OE1.B no hydrogen 3.366 N/A GLN 75.A N.A GLU 72.A O.A no hydrogen 3.189 N/A GLN 75.A N.A GLU 72.A O.B no hydrogen 3.263 N/A GLN 75.A N.B MET 71.A O no hydrogen 2.912 N/A GLN 75.A N.B GLU 72.A O.A no hydrogen 3.197 N/A GLN 75.A N.B GLU 72.A O.B no hydrogen 3.271 N/A ARG 76.A N MET 71.A O no hydrogen 3.161 N/A ARG 76.A NE ASP 226.A OD2 no hydrogen 2.734 N/A ARG 76.A NH1 ASP 226.A OD1 no hydrogen 2.957 N/A ARG 76.A NH1 ASP 226.A OD2 no hydrogen 3.538 N/A TYR 78.A N ILE 69.A O.A no hydrogen 2.946 N/A TYR 78.A N ILE 69.A O.B no hydrogen 2.961 N/A TYR 78.A OH ASP 226.A OD2 no hydrogen 2.573 N/A TYR 78.A OH THR 227.A OG1 no hydrogen 2.654 N/A ILE 79.A N VAL 208.A O no hydrogen 2.809 N/A LEU 80.A N SER 67.A O no hydrogen 2.878 N/A THR 81.A N VAL 210.A O no hydrogen 2.952 N/A THR 81.A OG1 ASN 65.A O no hydrogen 2.591 N/A GLN 82.A N ASN 65.A O no hydrogen 3.362 N/A GLN 82.A NE2 ARG 40.A O no hydrogen 2.916 N/A GLY 83.A N SER 213.A O.A no hydrogen 2.824 N/A LEU 85.A N THR 88.A OG1 no hydrogen 2.883 N/A ASN 87.A ND2.B ASN 39.A O no hydrogen 2.822 N/A THR 88.A N LEU 85.A O no hydrogen 2.946 N/A CYS 89.A SG LEU 85.A O no hydrogen 3.419 N/A PHE 92.A N THR 88.A O no hydrogen 2.887 N/A TRP 93.A N CYS 89.A O no hydrogen 3.103 N/A TRP 93.A NE1 TYR 121.A O no hydrogen 2.891 N/A GLU 94.A N GLY 90.A O no hydrogen 2.913 N/A MET 95.A N HIS 91.A O no hydrogen 2.905 N/A VAL 96.A N PHE 92.A O no hydrogen 3.052 N/A TRP 97.A N TRP 93.A O no hydrogen 2.953 N/A GLU 98.A N GLU 94.A O no hydrogen 2.858 N/A GLN 99.A N MET 95.A O no hydrogen 2.844 N/A LYS 100.A N TRP 97.A O no hydrogen 3.161 N/A SER 101.A N VAL 96.A O no hydrogen 3.154 N/A SER 101.A OG PRO 207.A O no hydrogen 2.685 N/A ARG 102.A NE SER 198.A O no hydrogen 3.156 N/A VAL 104.A N LEU 169.A O no hydrogen 2.913 N/A VAL 105.A N VAL 209.A O no hydrogen 2.725 N/A MET 106.A N PHE 171.A O no hydrogen 2.869 N/A LEU 107.A N HIS 211.A O no hydrogen 3.007 N/A ASN 108.A ND2 ARG 109.A O no hydrogen 2.891 N/A ARG 109.A N GLU 112.A OE2 no hydrogen 2.899 N/A ARG 109.A NH1 ASP 178.A OD1 no hydrogen 2.942 N/A GLU 112.A N SER 115.A O.A no hydrogen 3.031 N/A GLU 112.A N SER 115.A O.B no hydrogen 3.019 N/A LYS 113.A N ASP 178.A OD2 no hydrogen 3.120 N/A SER 115.A N.A GLU 112.A O no hydrogen 3.009 N/A SER 115.A N.B GLU 112.A O no hydrogen 3.000 N/A LYS 117.A N VAL 110.A O no hydrogen 2.747 N/A CYS 118.A SG ALA 119.A O no hydrogen 3.527 N/A ALA 119.A N PRO 84.A O no hydrogen 2.871 N/A GLN 120.A NE2 TRP 122.A O no hydrogen 2.979 N/A TYR 121.A OH HIS 211.A NE2 no hydrogen 2.598 N/A GLU 126.A N GLU 126.A OE1 no hydrogen 2.715 N/A GLU 127.A N GLU 127.A OE1 no hydrogen 2.741 N/A LYS 128.A N LYS 125.A O no hydrogen 3.074 N/A GLU 129.A N GLU 129.A OE1 no hydrogen 2.800 N/A MET 130.A N LEU 139.A O no hydrogen 2.911 N/A PHE 132.A N LEU 137.A O no hydrogen 2.882 N/A THR 135.A OG1 GLY 90.A O no hydrogen 3.030 N/A LEU 137.A N PHE 132.A O no hydrogen 3.231 N/A LYS 138.A N GLU 158.A O no hydrogen 2.887 N/A LEU 139.A N MET 130.A O no hydrogen 2.858 N/A THR 140.A N GLU 156.A O no hydrogen 2.911 N/A ILE 142.A N GLN 154.A O no hydrogen 2.820 N/A SER 143.A N.A GLN 154.A O no hydrogen 3.338 N/A SER 143.A N.B GLN 154.A O no hydrogen 3.324 N/A SER 143.A OG.A GLN 154.A OE1 no hydrogen 3.561 N/A ASP 145.A N VAL 152.A O no hydrogen 2.773 N/A LYS 147.A N TYR 150.A O no hydrogen 2.878 N/A LYS 147.A NZ ASP 145.A OD1 no hydrogen 3.220 N/A LYS 147.A NZ ASP 145.A OD2 no hydrogen 2.754 N/A THR 151.A N HIS 172.A O no hydrogen 2.871 N/A VAL 152.A N ASP 145.A O no hydrogen 2.944 N/A ARG 153.A N HIS 170.A O no hydrogen 2.833 N/A ARG 153.A NE GLU 144.A OE1 no hydrogen 2.746 N/A ARG 153.A NH1 HIS 170.A ND1 no hydrogen 3.014 N/A ARG 153.A NH1 HIS 172.A ND1 no hydrogen 3.015 N/A ARG 153.A NH2 HIS 172.A ND1 no hydrogen 3.448 N/A GLN 154.A N SER 143.A O.A no hydrogen 2.865 N/A GLN 154.A N SER 143.A O.B no hydrogen 2.855 N/A GLN 154.A NE2 GLU 167.A OE1.A no hydrogen 3.456 N/A LEU 155.A N ILE 168.A O no hydrogen 2.824 N/A GLU 156.A N THR 140.A O no hydrogen 2.877 N/A LEU 157.A N ARG 166.A O no hydrogen 2.897 N/A GLU 158.A N LYS 138.A O no hydrogen 2.804 N/A ASN 159.A N GLU 164.A O no hydrogen 2.974 N/A LEU 160.A N ASN 136.A O no hydrogen 2.989 N/A THR 161.A N ASN 159.A OD1 no hydrogen 3.041 N/A THR 161.A OG1 ASN 159.A OD1 no hydrogen 3.429 N/A GLN 163.A N ASN 159.A O no hydrogen 2.809 N/A GLU 164.A N THR 162.A OG1 no hydrogen 3.292 N/A ARG 166.A N LEU 157.A O no hydrogen 2.867 N/A ARG 166.A NH2 GLU 164.A OE2 no hydrogen 3.332 N/A ILE 168.A N LEU 155.A O no hydrogen 2.847 N/A LEU 169.A N ARG 102.A O no hydrogen 2.838 N/A HIS 170.A N ARG 153.A O no hydrogen 2.781 N/A HIS 170.A NE2 TYR 121.A OH no hydrogen 2.850 N/A PHE 171.A N VAL 104.A O no hydrogen 2.803 N/A HIS 172.A N THR 151.A O no hydrogen 2.833 N/A HIS 172.A NE2 ASN 108.A O no hydrogen 2.749 N/A TYR 173.A N MET 106.A O no hydrogen 2.868 N/A TYR 173.A OH SER 187.A OG no hydrogen 2.617 N/A THR 174.A N TYR 149.A O no hydrogen 3.220 N/A THR 174.A OG1 TYR 149.A O no hydrogen 3.254 N/A THR 175.A OG1 TYR 149.A O no hydrogen 2.924 N/A TRP 176.A NE1 GLY 180.A O no hydrogen 3.151 N/A ALA 186.A N SER 184.A OG no hydrogen 3.272 N/A SER 187.A OG TYR 173.A OH no hydrogen 2.617 N/A LEU 189.A N PRO 185.A O no hydrogen 2.851 N/A ASN 190.A N.A ALA 186.A O no hydrogen 2.952 N/A ASN 190.A N.B ALA 186.A O no hydrogen 2.958 N/A PHE 191.A N SER 187.A O no hydrogen 2.945 N/A LEU 192.A N PHE 188.A O no hydrogen 2.895 N/A PHE 193.A N LEU 189.A O no hydrogen 2.890 N/A LYS 194.A N ASN 190.A O.A no hydrogen 2.932 N/A LYS 194.A N ASN 190.A O.B no hydrogen 2.918 N/A LYS 194.A NZ GLU 197.A OE1.A no hydrogen 3.099 N/A VAL 195.A N PHE 191.A O no hydrogen 2.992 N/A ARG 196.A N LEU 192.A O no hydrogen 2.889 N/A ARG 196.A NE ASP 226.A OD1 no hydrogen 2.821 N/A ARG 196.A NH2 ASP 226.A O no hydrogen 3.109 N/A ARG 196.A NH2 ASP 226.A OD1 no hydrogen 3.074 N/A GLU 197.A N.A PHE 193.A O no hydrogen 2.888 N/A GLU 197.A N.B PHE 193.A O no hydrogen 2.869 N/A SER 198.A N VAL 195.A O no hydrogen 3.228 N/A SER 198.A OG VAL 195.A O no hydrogen 2.602 N/A SER 198.A OG SER 200.A OG no hydrogen 2.779 N/A GLY 199.A N ARG 196.A O no hydrogen 3.116 N/A SER 200.A N SER 198.A OG no hydrogen 3.106 N/A SER 200.A OG SER 198.A OG no hydrogen 2.779 N/A SER 202.A N GLY 199.A O no hydrogen 3.127 N/A SER 202.A OG GLY 199.A O no hydrogen 3.368 N/A HIS 205.A N SER 202.A O no hydrogen 3.125 N/A GLY 206.A N LYS 100.A O no hydrogen 2.901 N/A VAL 209.A N GLY 103.A O no hydrogen 3.007 N/A VAL 210.A N ILE 79.A O no hydrogen 2.779 N/A HIS 211.A N VAL 105.A O no hydrogen 2.932 N/A HIS 211.A ND1 CYS 212.A O.A no hydrogen 2.711 N/A HIS 211.A NE2 TYR 121.A OH no hydrogen 2.598 N/A CYS 212.A SG.A SER 213.A O.B no hydrogen 3.716 N/A CYS 212.A SG.A GLY 217.A O.B no hydrogen 2.200 N/A CYS 212.A SG.A SER 219.A OG no hydrogen 3.612 N/A CYS 212.A SG.B SER 213.A O.B no hydrogen 3.622 N/A CYS 212.A SG.B SER 213.A OG.B no hydrogen 3.521 N/A SER 213.A OG.A LYS 117.A O no hydrogen 2.810 N/A SER 213.A OG.B GLU 112.A OE1 no hydrogen 3.327 N/A ARG 218.A NH1.A LEU 107.A O no hydrogen 3.025 N/A ARG 218.A NH1.A GLU 112.A OE1 no hydrogen 3.421 N/A ARG 218.A NH1.A GLU 112.A OE2 no hydrogen 2.902 N/A ARG 218.A NH1.B LEU 107.A O no hydrogen 2.906 N/A ARG 218.A NH1.B GLU 112.A OE2 no hydrogen 2.935 N/A ARG 218.A NH2.A GLU 112.A OE1 no hydrogen 3.007 N/A ARG 218.A NH2.B GLU 112.A OE1 no hydrogen 3.083 N/A GLY 220.A N ILE 216.A O.A no hydrogen 2.873 N/A THR 221.A N.A GLY 217.A O.A no hydrogen 3.239 N/A THR 221.A N.B GLY 217.A O.A no hydrogen 3.235 N/A THR 221.A N.B ARG 218.A O.A no hydrogen 3.128 N/A THR 221.A N.B ARG 218.A O.B no hydrogen 2.971 N/A THR 221.A OG1.A GLY 217.A O.A no hydrogen 3.416 N/A THR 221.A OG1.A SER 267.A OG no hydrogen 3.238 N/A THR 221.A OG1.B ARG 218.A O.A no hydrogen 2.660 N/A THR 221.A OG1.B ARG 218.A O.B no hydrogen 2.562 N/A PHE 222.A N ARG 218.A O.A no hydrogen 3.138 N/A PHE 222.A N ARG 218.A O.B no hydrogen 3.274 N/A CYS 223.A N SER 219.A O no hydrogen 3.223 N/A CYS 223.A SG.A SER 219.A O no hydrogen 3.574 N/A CYS 223.A SG.A GLY 220.A O no hydrogen 3.460 N/A CYS 223.A SG.B SER 219.A O no hydrogen 3.517 N/A LEU 224.A N GLY 220.A O no hydrogen 2.867 N/A ALA 225.A N THR 221.A O.A no hydrogen 2.968 N/A ALA 225.A N THR 221.A O.B no hydrogen 3.062 N/A ASP 226.A N PHE 222.A O no hydrogen 3.037 N/A THR 227.A N CYS 223.A O no hydrogen 2.901 N/A THR 227.A OG1 TYR 78.A OH no hydrogen 2.654 N/A THR 227.A OG1 CYS 223.A O no hydrogen 3.404 N/A CYS 228.A N LEU 224.A O no hydrogen 2.920 N/A CYS 228.A SG LEU 224.A O no hydrogen 3.306 N/A LEU 229.A N ALA 225.A O no hydrogen 3.015 N/A LEU 230.A N ASP 226.A O no hydrogen 3.071 N/A LEU 231.A N THR 227.A O no hydrogen 2.935 N/A MET 232.A N CYS 228.A O no hydrogen 2.971 N/A ASP 233.A N LEU 229.A O no hydrogen 3.278 N/A ASP 233.A N LEU 230.A O no hydrogen 3.142 N/A LYS 234.A N LEU 230.A O no hydrogen 3.052 N/A LYS 234.A N LEU 231.A O no hydrogen 3.189 N/A ARG 235.A N LEU 231.A O no hydrogen 2.898 N/A ARG 235.A NE GLU 73.A OE2 no hydrogen 2.838 N/A ARG 235.A NH1 SER 240.A OG no hydrogen 2.990 N/A ARG 235.A NH2 GLU 73.A OE1 no hydrogen 2.839 N/A SER 239.A OG ASP 237.A OD1 no hydrogen 2.621 N/A SER 240.A N ASP 237.A O no hydrogen 3.075 N/A SER 240.A OG ASP 237.A O no hydrogen 2.816 N/A VAL 241.A N PRO 238.A O no hydrogen 3.281 N/A LYS 244.A N ASP 242.A OD1 no hydrogen 3.143 N/A LYS 244.A NZ GLU 3.A OE2 no hydrogen 2.755 N/A LYS 244.A NZ ASP 242.A OD1 no hydrogen 2.811 N/A LYS 244.A NZ ASP 242.A OD2 no hydrogen 3.436 N/A VAL 246.A N ASP 242.A O no hydrogen 2.974 N/A LEU 247.A N ILE 243.A O no hydrogen 2.840 N/A LEU 248.A N LYS 244.A O no hydrogen 2.956 N/A GLU 249.A N LYS 245.A O no hydrogen 2.965 N/A MET 250.A N VAL 246.A O no hydrogen 2.882 N/A ARG 251.A N LEU 247.A O no hydrogen 2.833 N/A ARG 251.A NE LEU 257.A O no hydrogen 2.900 N/A ARG 251.A NH2 TYR 17.A OH no hydrogen 3.386 N/A ARG 251.A NH2 LEU 257.A O no hydrogen 2.861 N/A ARG 251.A NH2 ILE 258.A O no hydrogen 2.648 N/A LYS 252.A N GLU 249.A O no hydrogen 3.162 N/A LYS 252.A NZ GLU 249.A OE1 no hydrogen 2.610 N/A PHE 253.A N MET 250.A O no hydrogen 2.912 N/A ARG 254.A NE GLY 215.A O.A no hydrogen 3.341 N/A ARG 254.A NH1 ASN 65.A OD1 no hydrogen 3.029 N/A ARG 254.A NH1 SER 67.A OG no hydrogen 2.906 N/A ARG 254.A NH2 ASN 65.A OD1 no hydrogen 2.848 N/A ARG 254.A NH2 ALA 214.A O.A no hydrogen 3.343 N/A ILE 258.A N ILE 216.A O.A no hydrogen 3.205 N/A GLN 259.A N GLN 263.A OE1 no hydrogen 2.829 N/A GLN 259.A NE2 GLY 215.A O.B no hydrogen 2.963 N/A GLN 263.A N THR 260.A OG1 no hydrogen 3.051 N/A GLN 263.A NE2 ILE 216.A O.B no hydrogen 2.832 N/A LEU 264.A N THR 260.A O no hydrogen 3.183 N/A ARG 265.A N ALA 261.A O no hydrogen 2.975 N/A ARG 265.A NE ASP 8.A OD1 no hydrogen 2.874 N/A ARG 265.A NH2 ASP 8.A OD1 no hydrogen 3.487 N/A ARG 265.A NH2 ASP 8.A OD2 no hydrogen 2.902 N/A PHE 266.A N ASP 262.A O no hydrogen 2.856 N/A SER 267.A N GLN 263.A O no hydrogen 2.898 N/A SER 267.A OG GLN 263.A O no hydrogen 2.910 N/A TYR 268.A N LEU 264.A O no hydrogen 3.066 N/A TYR 268.A OH GLU 3.A OE2 no hydrogen 2.710 N/A LEU 269.A N ARG 265.A O no hydrogen 3.001 N/A ALA 270.A N PHE 266.A O no hydrogen 2.878 N/A VAL 271.A N SER 267.A O no hydrogen 3.003 N/A ILE 272.A N TYR 268.A O no hydrogen 2.884 N/A GLU 273.A N LEU 269.A O no hydrogen 2.964 N/A GLY 274.A N ALA 270.A O no hydrogen 2.865 N/A ALA 275.A N VAL 271.A O no hydrogen 2.891 N/A LYS 276.A N ILE 272.A O no hydrogen 3.217 N/A PHE 277.A N GLU 273.A O no hydrogen 3.168 N/A ILE 278.A N GLY 274.A O no hydrogen 2.905 N/A