Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7kxq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 7.A N GLY 4.A O no hydrogen 2.863 N/A ILE 8.A N VAL 74.A O no hydrogen 2.717 N/A LYS 11.A N ASP 9.A OD1 no hydrogen 2.952 N/A ASP 12.A N ASP 9.A O no hydrogen 2.853 N/A LEU 13.A N PRO 10.A O no hydrogen 3.051 N/A THR 14.A N LYS 31.A O no hydrogen 2.840 N/A LEU 16.A N TYR 29.A O no hydrogen 2.831 N/A LYS 17.A N TYR 29.A O no hydrogen 3.145 N/A LEU 19.A N VAL 27.A O no hydrogen 2.809 N/A GLY 22.A N GLY 25.A O no hydrogen 2.861 N/A GLN 23.A NE2 ASP 159.A OD2 no hydrogen 2.893 N/A GLY 25.A N GLY 22.A O no hydrogen 2.965 N/A VAL 27.A N GLY 20.A O no hydrogen 2.821 N/A LYS 28.A N ILE 40.A O no hydrogen 2.838 N/A TYR 29.A N LYS 17.A O no hydrogen 2.685 N/A TYR 29.A OH ASP 37.A OD1 no hydrogen 2.783 N/A GLY 30.A N VAL 38.A O no hydrogen 2.995 N/A LYS 31.A N THR 14.A O no hydrogen 2.886 N/A LYS 31.A NZ ASP 37.A OD1 no hydrogen 2.654 N/A TRP 32.A N TYR 36.A O no hydrogen 2.791 N/A ARG 33.A N ASP 12.A O no hydrogen 2.798 N/A ARG 33.A NE ASP 12.A OD2 no hydrogen 2.847 N/A ARG 33.A NH2 ASP 12.A OD2 no hydrogen 3.120 N/A GLN 35.A N TRP 32.A O no hydrogen 3.219 N/A TYR 36.A N TRP 32.A O no hydrogen 3.154 N/A VAL 38.A N GLY 30.A O no hydrogen 2.908 N/A ALA 39.A N THR 85.A O no hydrogen 2.816 N/A ILE 40.A N LYS 28.A O no hydrogen 2.746 N/A LYS 41.A N ILE 83.A O no hydrogen 2.841 N/A LYS 41.A NZ ASP 150.A OD1 no hydrogen 2.991 N/A LYS 41.A NZ ASP 150.A OD2 no hydrogen 3.072 N/A MET 42.A N VAL 26.A O no hydrogen 2.912 N/A ILE 43.A N ILE 81.A O no hydrogen 2.938 N/A LYS 44.A N PHE 24.A O no hydrogen 2.813 N/A SER 47.A N LYS 44.A O no hydrogen 3.028 N/A SER 47.A OG LYS 44.A O no hydrogen 2.725 N/A SER 49.A N TYR 156.A O no hydrogen 2.805 N/A PHE 53.A N SER 49.A O no hydrogen 3.038 N/A ILE 54.A N GLU 50.A O no hydrogen 2.822 N/A GLU 55.A N ASP 51.A O no hydrogen 3.161 N/A GLU 56.A N GLU 52.A O no hydrogen 3.070 N/A ALA 57.A N PHE 53.A O no hydrogen 2.708 N/A ALA 57.A N ILE 54.A O no hydrogen 3.263 N/A LYS 58.A NZ GLU 55.A OE1 no hydrogen 3.022 N/A MET 60.A N GLU 56.A O no hydrogen 2.973 N/A MET 61.A N ALA 57.A O no hydrogen 2.927 N/A ASN 62.A N VAL 59.A O no hydrogen 3.154 N/A LEU 63.A N MET 60.A O no hydrogen 3.010 N/A SER 64.A N TYR 122.A OH no hydrogen 3.013 N/A HIS 65.A N GLN 70.A OE1.B no hydrogen 3.272 N/A LYS 67.A N HIS 65.A ND1 no hydrogen 2.965 N/A LYS 67.A NZ ASP 115.A OD1 no hydrogen 2.737 N/A LYS 67.A NZ GLU 118.A OE1 no hydrogen 2.774 N/A LEU 68.A N HIS 65.A O no hydrogen 3.008 N/A VAL 69.A N VAL 148.A O no hydrogen 2.874 N/A GLN 70.A N GLU 86.A OE1 no hydrogen 2.976 N/A GLN 70.A NE2.A MET 61.A O no hydrogen 3.211 N/A GLN 70.A NE2.A LEU 71.A O no hydrogen 3.287 N/A GLN 70.A NE2.B LEU 63.A O no hydrogen 2.996 N/A TYR 72.A N ILE 84.A O no hydrogen 2.775 N/A GLY 73.A N ILE 84.A O no hydrogen 3.294 N/A VAL 74.A N TRP 6.A O no hydrogen 2.824 N/A CYS 75.A N PHE 82.A O no hydrogen 2.889 N/A CYS 75.A SG ILE 8.A O no hydrogen 3.326 N/A THR 76.A N GLU 7.A OE1 no hydrogen 2.639 N/A THR 76.A OG1 GLU 7.A OE1 no hydrogen 2.872 N/A THR 76.A OG1 GLU 7.A OE2 no hydrogen 2.828 N/A GLN 78.A NE2 PRO 80.A O no hydrogen 2.658 N/A PHE 82.A N CYS 75.A O no hydrogen 2.965 N/A ILE 83.A N LYS 41.A O no hydrogen 2.931 N/A ILE 84.A N GLY 73.A O no hydrogen 2.847 N/A THR 85.A N ALA 39.A O no hydrogen 2.877 N/A THR 85.A OG1 GLU 86.A O no hydrogen 2.996 N/A GLU 86.A N GLN 70.A O no hydrogen 2.889 N/A ASN 90.A N VAL 140.A O no hydrogen 2.862 N/A ASN 90.A ND2 ASN 141.A O no hydrogen 3.026 N/A GLY 91.A N MET 88.A O no hydrogen 3.183 N/A CYS 92.A SG.B ALA 135.A O no hydrogen 3.933 N/A CYS 92.A SG.B ARG 136.A O no hydrogen 3.464 N/A LEU 93.A N CYS 138.A O no hydrogen 2.823 N/A TYR 96.A N CYS 92.A O no hydrogen 3.027 N/A LEU 97.A N LEU 93.A O no hydrogen 2.849 N/A ARG 98.A N LEU 94.A O no hydrogen 3.198 N/A ARG 98.A NE GLY 205.A O no hydrogen 2.755 N/A ARG 98.A NH2 GLY 205.A O no hydrogen 2.892 N/A GLU 99.A N ASN 95.A O no hydrogen 3.184 N/A GLU 99.A N TYR 96.A O no hydrogen 3.292 N/A ARG 101.A NE GLU 99.A OE2.B no hydrogen 2.616 N/A ARG 101.A NH2 GLU 99.A OE2.A no hydrogen 3.119 N/A ARG 101.A NH2 GLU 99.A OE2.B no hydrogen 3.083 N/A HIS 102.A N GLU 99.A O no hydrogen 3.260 N/A HIS 102.A NE2 GLU 99.A OE1.A no hydrogen 2.824 N/A ARG 103.A N MET 100.A O no hydrogen 2.975 N/A GLN 105.A N GLN 108.A OE1 no hydrogen 2.853 N/A GLN 105.A NE2.B ARG 103.A O no hydrogen 2.698 N/A GLN 107.A N GLN 107.A OE1 no hydrogen 2.859 N/A GLN 107.A NE2 SER 270.A O no hydrogen 2.876 N/A LEU 109.A N GLN 105.A O no hydrogen 3.139 N/A LEU 110.A N THR 106.A O no hydrogen 2.984 N/A GLU 111.A N GLN 107.A O no hydrogen 2.980 N/A MET 112.A N GLN 108.A O no hydrogen 3.027 N/A CYS 113.A N LEU 109.A O no hydrogen 3.146 N/A CYS 113.A SG LEU 109.A O no hydrogen 3.489 N/A LYS 114.A N LEU 110.A O no hydrogen 2.865 N/A LYS 114.A NZ GLU 118.A OE2 no hydrogen 2.955 N/A ASP 115.A N GLU 111.A O no hydrogen 2.906 N/A VAL 116.A N MET 112.A O no hydrogen 3.175 N/A CYS 117.A N CYS 113.A O no hydrogen 2.845 N/A CYS 117.A SG PHE 255.A O no hydrogen 3.495 N/A GLU 118.A N LYS 114.A O no hydrogen 2.809 N/A ALA 119.A N ASP 115.A O no hydrogen 3.234 N/A MET 120.A N VAL 116.A O no hydrogen 2.901 N/A GLU 121.A N CYS 117.A O no hydrogen 2.780 N/A TYR 122.A N GLU 118.A O no hydrogen 3.059 N/A LEU 123.A N ALA 119.A O no hydrogen 2.946 N/A GLU 124.A N MET 120.A O no hydrogen 2.800 N/A SER 125.A N GLU 121.A O no hydrogen 2.961 N/A SER 125.A OG TYR 122.A O no hydrogen 2.650 N/A LYS 126.A N TYR 122.A O no hydrogen 3.216 N/A LYS 126.A N LEU 123.A O no hydrogen 2.956 N/A GLN 127.A N GLU 124.A O no hydrogen 2.958 N/A GLN 127.A NE2.B SER 125.A O no hydrogen 3.218 N/A PHE 128.A N LEU 123.A O no hydrogen 2.953 N/A HIS 130.A N ASP 190.A OD2 no hydrogen 2.738 N/A HIS 130.A NE2 SER 149.A O no hydrogen 2.850 N/A ARG 131.A N ASP 190.A OD1 no hydrogen 3.023 N/A ASP 132.A N HIS 130.A ND1 no hydrogen 2.993 N/A ALA 135.A N GLU 200.A OE2 no hydrogen 2.879 N/A ARG 136.A NH2 ASP 132.A OD1 no hydrogen 2.844 N/A ASN 137.A N ALA 134.A O no hydrogen 2.871 N/A ASN 137.A ND2 ASP 132.A O no hydrogen 2.775 N/A CYS 138.A N ALA 135.A O no hydrogen 3.151 N/A CYS 138.A SG ALA 134.A O no hydrogen 3.658 N/A LEU 139.A N LYS 147.A O no hydrogen 2.895 N/A VAL 140.A N GLY 91.A O no hydrogen 2.802 N/A ASN 141.A N VAL 145.A O no hydrogen 2.935 N/A GLN 143.A N ASN 141.A OD1 no hydrogen 2.808 N/A GLN 143.A NE2 ASP 142.A OD1 no hydrogen 3.287 N/A GLY 144.A N ASN 141.A O no hydrogen 2.980 N/A VAL 145.A N ASN 141.A OD1 no hydrogen 2.950 N/A VAL 146.A N ASP 115.A OD2 no hydrogen 2.942 N/A LYS 147.A N LEU 139.A O no hydrogen 2.841 N/A LYS 147.A NZ GLU 66.A O no hydrogen 2.915 N/A LYS 147.A NZ GLU 86.A OE2 no hydrogen 2.745 N/A VAL 148.A N LYS 67.A O no hydrogen 2.895 N/A SER 149.A N ASN 137.A O no hydrogen 3.026 N/A GLY 152.A N HIS 130.A O no hydrogen 3.033 N/A LEU 153.A N ASP 150.A O no hydrogen 3.367 N/A ARG 155.A N GLY 152.A O no hydrogen 3.298 N/A ARG 155.A NE GLY 152.A O no hydrogen 2.863 N/A ARG 155.A NH1 GLU 56.A OE2 no hydrogen 3.188 N/A ARG 155.A NH2 GLU 56.A OE2 no hydrogen 2.887 N/A ARG 155.A NH2 GLY 152.A O no hydrogen 3.373 N/A TYR 156.A N LEU 153.A O no hydrogen 2.926 N/A VAL 157.A N SER 154.A O no hydrogen 3.244 N/A LEU 158.A N SER 47.A O no hydrogen 3.005 N/A GLU 161.A N ASP 159.A OD1 no hydrogen 2.922 N/A TYR 162.A N ASP 159.A O no hydrogen 2.965 N/A TYR 162.A OH ASP 132.A OD2 no hydrogen 2.541 N/A THR 163.A N ASP 159.A O no hydrogen 3.056 N/A THR 163.A OG1 ASP 159.A O no hydrogen 3.489 N/A SER 164.A N ASP 160.A O no hydrogen 2.915 N/A VAL 166.A N SER 164.A OG no hydrogen 3.209 N/A GLY 167.A N SER 164.A O no hydrogen 2.811 N/A SER 168.A N GLU 161.A OE1 no hydrogen 2.881 N/A SER 168.A OG GLU 161.A OE1 no hydrogen 3.323 N/A LYS 169.A N GLU 161.A O no hydrogen 2.800 N/A LYS 169.A NZ ASP 159.A OD2 no hydrogen 2.679 N/A PHE 170.A N GLY 167.A O no hydrogen 3.343 N/A VAL 172.A N PHE 170.A O no hydrogen 2.756 N/A ARG 173.A NE ASN 214.A OD1 no hydrogen 2.990 N/A ARG 173.A NH1 PRO 208.A O no hydrogen 2.956 N/A ARG 173.A NH1 TYR 209.A O no hydrogen 2.889 N/A ARG 173.A NH1 PHE 212.A O no hydrogen 3.108 N/A ARG 173.A NH2 PHE 212.A O no hydrogen 2.793 N/A TRP 174.A N PRO 171.A O no hydrogen 3.058 N/A TRP 174.A NE1 GLU 200.A OE2 no hydrogen 2.868 N/A SER 175.A N VAL 172.A O no hydrogen 3.130 N/A SER 175.A OG PRO 171.A O no hydrogen 2.792 N/A GLU 178.A N GLU 178.A OE1 no hydrogen 2.796 N/A VAL 179.A N PRO 176.A O no hydrogen 3.051 N/A LEU 180.A N PRO 176.A O no hydrogen 3.106 N/A MET 181.A N PRO 177.A O no hydrogen 2.791 N/A TYR 182.A N GLU 178.A O no hydrogen 2.999 N/A SER 183.A N VAL 179.A O no hydrogen 2.668 N/A SER 183.A OG VAL 179.A O no hydrogen 3.481 N/A LYS 184.A N GLU 178.A O no hydrogen 3.090 N/A SER 186.A N SER 189.A OG no hydrogen 2.886 N/A LYS 188.A N SER 186.A OG no hydrogen 2.958 N/A LYS 188.A NZ ARG 252.A O no hydrogen 2.955 N/A LYS 188.A NZ PRO 253.A O no hydrogen 3.054 N/A SER 189.A N SER 186.A O no hydrogen 2.972 N/A SER 189.A OG SER 186.A O no hydrogen 2.844 N/A ASP 190.A N SER 186.A O no hydrogen 3.380 N/A ILE 191.A N SER 187.A O no hydrogen 2.989 N/A TRP 192.A N LYS 188.A O no hydrogen 3.108 N/A ALA 193.A N SER 189.A O no hydrogen 3.027 N/A PHE 194.A N ASP 190.A O no hydrogen 2.837 N/A GLY 195.A N ILE 191.A O no hydrogen 3.063 N/A VAL 196.A N TRP 192.A O no hydrogen 3.102 N/A LEU 197.A N ALA 193.A O no hydrogen 2.837 N/A MET 198.A N PHE 194.A O no hydrogen 2.817 N/A TRP 199.A N GLY 195.A O no hydrogen 3.002 N/A TRP 199.A NE1 TYR 228.A O no hydrogen 2.933 N/A GLU 200.A N VAL 196.A O no hydrogen 2.793 N/A ILE 201.A N LEU 197.A O no hydrogen 2.902 N/A TYR 202.A N MET 198.A O no hydrogen 2.977 N/A SER 203.A N TRP 199.A O no hydrogen 2.797 N/A SER 203.A OG TRP 199.A O no hydrogen 2.660 N/A LEU 204.A N ILE 201.A O no hydrogen 3.065 N/A GLY 205.A N GLU 200.A O no hydrogen 2.821 N/A LYS 206.A N SER 203.A O no hydrogen 3.408 N/A PHE 212.A N TYR 209.A O no hydrogen 2.866 N/A THR 213.A N GLU 216.A OE1 no hydrogen 2.965 N/A GLU 216.A N THR 213.A OG1 no hydrogen 3.047 N/A THR 217.A N THR 213.A O no hydrogen 2.880 N/A THR 217.A OG1 THR 213.A O no hydrogen 2.899 N/A ALA 218.A N ASN 214.A O no hydrogen 2.971 N/A GLU 219.A N SER 215.A O no hydrogen 3.174 N/A HIS 220.A N GLU 216.A O no hydrogen 2.913 N/A ILE 221.A N THR 217.A O no hydrogen 2.892 N/A ALA 222.A N ALA 218.A O no hydrogen 3.026 N/A GLN 223.A N GLU 219.A O no hydrogen 3.041 N/A GLN 223.A N HIS 220.A O no hydrogen 3.174 N/A GLN 223.A NE2 GLU 219.A OE2 no hydrogen 2.983 N/A GLY 224.A N ILE 221.A O no hydrogen 3.056 N/A LEU 225.A N HIS 220.A O no hydrogen 3.017 N/A ARG 226.A NE TRP 245.A O no hydrogen 2.939 N/A ARG 226.A NH1 ILE 221.A O no hydrogen 3.101 N/A ARG 226.A NH1 LEU 225.A O no hydrogen 2.843 N/A ARG 226.A NH2 TRP 245.A O no hydrogen 2.926 N/A ARG 229.A NE ALA 233.A O no hydrogen 2.689 N/A ARG 229.A NH2 ALA 233.A O no hydrogen 3.100 N/A ALA 233.A N PRO 230.A O no hydrogen 2.983 N/A SER 234.A OG GLU 269.A OE1 no hydrogen 3.533 N/A SER 234.A OG GLU 269.A OE2 no hydrogen 2.413 N/A LYS 236.A NZ GLU 268.A OE1 no hydrogen 3.210 N/A VAL 237.A N SER 234.A OG no hydrogen 3.095 N/A TYR 238.A N SER 234.A O no hydrogen 2.889 N/A TYR 238.A OH LEU 227.A O no hydrogen 3.356 N/A THR 239.A N GLU 235.A O no hydrogen 2.915 N/A THR 239.A OG1 GLU 235.A O no hydrogen 2.934 N/A ILE 240.A N LYS 236.A O no hydrogen 3.225 N/A MET 241.A N VAL 237.A O no hydrogen 3.118 N/A TYR 242.A N TYR 238.A O no hydrogen 2.799 N/A SER 243.A N THR 239.A O no hydrogen 2.979 N/A SER 243.A N ILE 240.A O no hydrogen 3.157 N/A SER 243.A OG ILE 240.A O no hydrogen 2.651 N/A CYS 244.A N MET 241.A O no hydrogen 3.018 N/A CYS 244.A SG ILE 240.A O no hydrogen 3.751 N/A TRP 245.A N TYR 242.A O no hydrogen 2.985 N/A LYS 248.A NZ.B ASP 250.A OD2 no hydrogen 2.897 N/A GLU 251.A N LYS 248.A O no hydrogen 2.957 N/A ARG 252.A N ALA 249.A O no hydrogen 3.027 N/A ARG 252.A NE HIS 246.A O no hydrogen 2.804 N/A ARG 252.A NH1 GLU 178.A OE2 no hydrogen 2.783 N/A ARG 252.A NH1 LYS 188.A O no hydrogen 2.974 N/A ARG 252.A NH2 GLU 178.A OE1 no hydrogen 2.926 N/A ARG 252.A NH2 HIS 246.A O no hydrogen 2.980 N/A PHE 255.A N GLU 124.A OE1.B no hydrogen 2.894 N/A PHE 255.A N GLU 124.A OE2.A no hydrogen 2.855 N/A ILE 257.A N THR 254.A OG1 no hydrogen 3.075 N/A LEU 258.A N THR 254.A O no hydrogen 2.957 N/A LEU 259.A N PHE 255.A O no hydrogen 2.848 N/A SER 260.A N LYS 256.A O no hydrogen 3.076 N/A ASN 261.A N ILE 257.A O no hydrogen 2.928 N/A ILE 262.A N LEU 258.A O no hydrogen 2.837 N/A LEU 263.A N LEU 259.A O no hydrogen 2.885 N/A ASP 264.A N SER 260.A O no hydrogen 2.927 N/A VAL 265.A N ASN 261.A O no hydrogen 2.972 N/A MET 266.A N ILE 262.A O no hydrogen 2.891 N/A ASP 267.A N LEU 263.A O no hydrogen 2.988 N/A GLU 268.A N ASP 264.A O no hydrogen 2.981 N/A GLU 269.A N VAL 265.A O no hydrogen 2.760 N/A