Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7kxz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A ND2 TYR 65.A OH no hydrogen 3.345 N/A ASN 5.A ND2 SER 69.A OG no hydrogen 2.838 N/A ALA 7.A N ASN 5.A OD1 no hydrogen 3.128 N/A LEU 12.A N ILE 81.A O no hydrogen 2.818 N/A GLU 16.A N LYS 13.A O no hydrogen 3.076 N/A PHE 17.A N GLU 14.A O no hydrogen 3.320 N/A LYS 18.A N LEU 35.A O no hydrogen 3.015 N/A LYS 19.A NZ GLU 51.A OE2 no hydrogen 3.387 N/A LYS 19.A NZ GLN 88.A OE1 no hydrogen 3.246 N/A ILE 20.A N LYS 33.A O no hydrogen 2.883 N/A LEU 23.A N VAL 31.A O no hydrogen 2.933 N/A GLY 24.A N VAL 31.A O no hydrogen 3.209 N/A SER 25.A OG GLY 29.A O no hydrogen 3.245 N/A GLY 26.A N GLY 29.A O no hydrogen 2.833 N/A THR 30.A N GLU 51.A O no hydrogen 3.070 N/A VAL 31.A N GLY 24.A O no hydrogen 2.814 N/A TYR 32.A N ILE 49.A O no hydrogen 2.659 N/A LYS 33.A N LYS 21.A O no hydrogen 2.942 N/A GLY 34.A N VAL 47.A O no hydrogen 2.994 N/A LEU 35.A N LYS 18.A O no hydrogen 3.081 N/A TRP 36.A N ILE 45.A O no hydrogen 2.830 N/A TRP 36.A NE1 GLU 16.A OE1 no hydrogen 3.320 N/A ILE 37.A N GLU 16.A O no hydrogen 2.887 N/A GLU 39.A N GLU 16.A OE2 no hydrogen 3.249 N/A GLU 41.A N PRO 38.A O no hydrogen 3.016 N/A VAL 43.A N GLU 41.A O no hydrogen 2.586 N/A LYS 44.A N ASP 291.A O no hydrogen 2.856 N/A ILE 45.A N TRP 36.A O no hydrogen 2.780 N/A VAL 47.A N GLY 34.A O no hydrogen 2.854 N/A ALA 48.A N THR 91.A O no hydrogen 2.823 N/A ILE 49.A N TYR 32.A O no hydrogen 2.831 N/A LYS 50.A N LEU 89.A O no hydrogen 2.807 N/A LYS 50.A NZ GLU 63.A OE1 no hydrogen 3.427 N/A LYS 50.A NZ GLU 63.A OE2 no hydrogen 2.474 N/A GLU 51.A N THR 30.A O no hydrogen 2.991 N/A LYS 55.A NZ GLU 59.A OE2 no hydrogen 2.946 N/A ASN 57.A N SER 53.A O no hydrogen 3.344 N/A LYS 58.A N PRO 54.A O no hydrogen 2.965 N/A LYS 58.A NZ ASP 62.A OD2 no hydrogen 2.997 N/A GLU 59.A N LYS 55.A O no hydrogen 3.025 N/A ILE 60.A N ALA 56.A O no hydrogen 3.037 N/A LEU 61.A N ASN 57.A O no hydrogen 3.033 N/A ASP 62.A N LYS 58.A O no hydrogen 2.953 N/A GLU 63.A N GLU 59.A O no hydrogen 3.019 N/A ALA 64.A N ILE 60.A O no hydrogen 2.879 N/A TYR 65.A N LEU 61.A O no hydrogen 2.840 N/A VAL 66.A N ASP 62.A O no hydrogen 3.245 N/A MET 67.A N GLU 63.A O no hydrogen 2.954 N/A ALA 68.A N ALA 64.A O no hydrogen 2.941 N/A SER 69.A N VAL 66.A O no hydrogen 2.945 N/A SER 69.A OG TYR 65.A O no hydrogen 2.725 N/A ASP 71.A N TYR 128.A OH no hydrogen 2.808 N/A HIS 74.A N ASN 72.A OD1 no hydrogen 2.883 N/A VAL 75.A N ASN 72.A O no hydrogen 3.114 N/A CYS 76.A N ILE 154.A O no hydrogen 2.938 N/A CYS 76.A SG ILE 154.A O no hydrogen 3.719 N/A ARG 77.A NE MET 67.A O no hydrogen 3.559 N/A ARG 77.A NH2 ALA 68.A O no hydrogen 2.931 N/A LEU 79.A N ILE 90.A O no hydrogen 2.743 N/A GLY 80.A N ILE 90.A O no hydrogen 3.176 N/A ILE 81.A N ARG 10.A O no hydrogen 2.953 N/A CYS 82.A N GLN 88.A O no hydrogen 3.035 N/A CYS 82.A SG LEU 12.A O no hydrogen 3.417 N/A THR 84.A OG1 THR 86.A O no hydrogen 2.537 N/A VAL 87.A N ASN 57.A OD1 no hydrogen 3.272 N/A GLN 88.A N CYS 82.A O no hydrogen 3.192 N/A LEU 89.A N LYS 50.A O no hydrogen 2.824 N/A ILE 90.A N GLY 80.A O no hydrogen 2.866 N/A THR 91.A N ALA 48.A O no hydrogen 2.806 N/A GLN 92.A NE2 ASP 294.A OD1 no hydrogen 3.499 N/A GLN 92.A NE2 ASP 296.A OD2 no hydrogen 3.117 N/A LEU 93.A N PRO 46.A O no hydrogen 3.276 N/A PHE 96.A N VAL 146.A O no hydrogen 3.177 N/A GLY 97.A N MET 94.A O no hydrogen 3.166 N/A LEU 99.A N VAL 144.A O no hydrogen 2.722 N/A LEU 100.A N ALA 141.A O no hydrogen 3.299 N/A TYR 102.A N CYS 98.A O no hydrogen 3.010 N/A VAL 103.A N LEU 99.A O no hydrogen 2.893 N/A ARG 104.A N LEU 100.A O no hydrogen 3.250 N/A ARG 104.A NE GLY 212.A O no hydrogen 2.847 N/A ARG 104.A NH2 GLY 212.A O no hydrogen 3.265 N/A GLU 105.A N ASP 101.A O no hydrogen 3.152 N/A HIS 106.A N TYR 102.A O no hydrogen 2.951 N/A LYS 107.A NZ ARG 104.A O no hydrogen 2.992 N/A ASN 109.A N HIS 106.A O no hydrogen 2.872 N/A ILE 110.A N LYS 107.A O no hydrogen 3.298 N/A SER 112.A N ASP 285.A OD1 no hydrogen 3.265 N/A SER 112.A N ASP 285.A OD2 no hydrogen 3.051 N/A SER 112.A OG ASP 285.A OD1 no hydrogen 3.496 N/A SER 112.A OG ASP 285.A OD2 no hydrogen 2.722 N/A GLN 113.A NE2 ALA 273.A O no hydrogen 3.668 N/A TYR 114.A N GLY 111.A O no hydrogen 3.113 N/A LEU 115.A N GLY 111.A O no hydrogen 3.199 N/A LEU 116.A N SER 112.A O no hydrogen 2.955 N/A ASN 117.A N GLN 113.A O no hydrogen 3.043 N/A ASN 117.A ND2 GLN 113.A OE1 no hydrogen 3.413 N/A TRP 118.A N TYR 114.A O no hydrogen 2.881 N/A TRP 118.A NE1 PRO 149.A O no hydrogen 2.890 N/A CYS 119.A N LEU 115.A O no hydrogen 3.189 N/A CYS 119.A SG LEU 115.A O no hydrogen 3.310 N/A VAL 120.A N LEU 116.A O no hydrogen 3.043 N/A GLN 121.A N ASN 117.A O no hydrogen 2.915 N/A GLN 121.A NE2 GLN 150.A O no hydrogen 2.792 N/A ILE 122.A N TRP 118.A O no hydrogen 2.912 N/A ALA 123.A N CYS 119.A O no hydrogen 3.105 N/A LYS 124.A N VAL 120.A O no hydrogen 2.872 N/A GLY 125.A N GLN 121.A O no hydrogen 2.928 N/A MET 126.A N ILE 122.A O no hydrogen 2.893 N/A ASN 127.A N ALA 123.A O no hydrogen 2.766 N/A TYR 128.A N LYS 124.A O no hydrogen 2.965 N/A LEU 129.A N GLY 125.A O no hydrogen 3.004 N/A GLU 130.A N MET 126.A O no hydrogen 2.907 N/A ASP 131.A N ASN 127.A O no hydrogen 2.988 N/A ARG 132.A N TYR 128.A O no hydrogen 3.029 N/A ARG 132.A NH1 SER 69.A O no hydrogen 3.049 N/A ARG 133.A N GLU 130.A O no hydrogen 2.990 N/A ARG 133.A NH1 GLY 164.A O no hydrogen 2.835 N/A ARG 133.A NH2 GLU 167.A O no hydrogen 3.273 N/A LEU 134.A N LEU 129.A O no hydrogen 2.818 N/A VAL 135.A N LYS 161.A O no hydrogen 3.052 N/A HIS 136.A N ASP 197.A OD2 no hydrogen 2.766 N/A HIS 136.A NE2 THR 155.A O no hydrogen 2.905 N/A ARG 137.A N ASP 197.A OD1 no hydrogen 2.984 N/A ARG 137.A NH1 LEU 159.A O no hydrogen 2.834 N/A ASP 138.A N HIS 136.A ND1 no hydrogen 2.997 N/A ALA 141.A N GLU 207.A OE1 no hydrogen 3.134 N/A ARG 142.A NH2 ASP 138.A OD1 no hydrogen 2.826 N/A ASN 143.A N ALA 140.A O no hydrogen 3.002 N/A ASN 143.A ND2 ASP 138.A O no hydrogen 2.721 N/A VAL 144.A N ALA 141.A O no hydrogen 3.255 N/A LEU 145.A N LYS 153.A O no hydrogen 2.901 N/A VAL 146.A N GLY 97.A O no hydrogen 2.925 N/A LYS 147.A N HIS 151.A O no hydrogen 2.916 N/A LYS 147.A NZ ASP 294.A OD2 no hydrogen 3.308 N/A LYS 147.A NZ ASP 296.A OD2 no hydrogen 2.507 N/A THR 148.A N HIS 151.A O no hydrogen 3.305 N/A THR 148.A OG1 GLN 150.A OE1 no hydrogen 3.417 N/A GLN 150.A N THR 148.A OG1 no hydrogen 3.210 N/A GLN 150.A NE2 TYR 114.A OH no hydrogen 2.787 N/A HIS 151.A N THR 148.A O no hydrogen 2.859 N/A HIS 151.A NE2 PRO 73.A O no hydrogen 2.655 N/A VAL 152.A N GLN 121.A OE1 no hydrogen 2.882 N/A LYS 153.A N LEU 145.A O no hydrogen 2.991 N/A LYS 153.A NZ GLN 92.A OE1 no hydrogen 2.711 N/A LYS 153.A NZ ASP 296.A OD1 no hydrogen 2.625 N/A LYS 153.A NZ ASP 296.A OD2 no hydrogen 2.964 N/A ILE 154.A N HIS 74.A O no hydrogen 2.979 N/A THR 155.A N ASN 143.A O no hydrogen 2.904 N/A ASP 156.A N THR 155.A OG1 no hydrogen 2.700 N/A GLY 158.A N ASP 156.A OD1 no hydrogen 3.331 N/A ALA 160.A N PHE 157.A O no hydrogen 3.174 N/A LYS 161.A N VAL 135.A O no hydrogen 2.929 N/A LYS 161.A NZ LEU 159.A O no hydrogen 3.284 N/A LYS 161.A NZ ALA 160.A O no hydrogen 3.171 N/A LEU 163.A N ARG 133.A O no hydrogen 2.928 N/A GLY 164.A N GLU 167.A OE1 no hydrogen 3.150 N/A GLU 167.A N GLY 164.A O no hydrogen 3.018 N/A TYR 170.A N TYR 192.A O no hydrogen 2.834 N/A ALA 172.A N ARG 190.A O no hydrogen 3.166 N/A LYS 180.A NZ PRO 215.A O no hydrogen 3.505 N/A LYS 180.A NZ TYR 216.A O no hydrogen 2.972 N/A LYS 180.A NZ ILE 219.A O no hydrogen 2.576 N/A TRP 181.A N PRO 178.A O no hydrogen 3.201 N/A TRP 181.A NE1 GLU 207.A OE1 no hydrogen 2.696 N/A MET 182.A N ILE 179.A O no hydrogen 3.231 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.778 N/A SER 186.A N ALA 183.A O no hydrogen 2.982 N/A SER 186.A OG ILE 191.A O no hydrogen 2.771 N/A ILE 187.A N ALA 183.A O no hydrogen 3.078 N/A LEU 188.A N LEU 184.A O no hydrogen 2.947 N/A HIS 189.A N GLU 185.A O no hydrogen 2.901 N/A ARG 190.A N SER 186.A O no hydrogen 2.874 N/A TYR 192.A N TYR 170.A O no hydrogen 3.051 N/A THR 193.A N SER 196.A OG no hydrogen 3.005 N/A GLN 195.A NE2 ALA 256.A O no hydrogen 3.182 N/A GLN 195.A NE2 PRO 260.A O no hydrogen 3.331 N/A SER 196.A N THR 193.A O no hydrogen 3.242 N/A SER 196.A N THR 193.A OG1 no hydrogen 3.115 N/A SER 196.A OG THR 193.A O no hydrogen 3.056 N/A ASP 197.A N THR 193.A O no hydrogen 3.164 N/A VAL 198.A N HIS 194.A O no hydrogen 2.989 N/A TRP 199.A N GLN 195.A O no hydrogen 3.364 N/A SER 200.A N SER 196.A O no hydrogen 3.324 N/A SER 200.A OG TRP 181.A O no hydrogen 2.615 N/A SER 200.A OG SER 196.A O no hydrogen 3.444 N/A TYR 201.A N ASP 197.A O no hydrogen 2.801 N/A TYR 201.A OH CYS 119.A O no hydrogen 2.650 N/A GLY 202.A N VAL 198.A O no hydrogen 2.969 N/A VAL 203.A N TRP 199.A O no hydrogen 3.041 N/A THR 204.A N SER 200.A O no hydrogen 2.869 N/A THR 204.A OG1 SER 200.A O no hydrogen 2.737 N/A VAL 205.A N TYR 201.A O no hydrogen 2.836 N/A TRP 206.A N GLY 202.A O no hydrogen 3.081 N/A TRP 206.A NE1 PRO 235.A O no hydrogen 2.929 N/A GLU 207.A N VAL 203.A O no hydrogen 2.861 N/A LEU 208.A N THR 204.A O no hydrogen 3.030 N/A MET 209.A N VAL 205.A O no hydrogen 2.855 N/A THR 210.A N TRP 206.A O no hydrogen 3.052 N/A THR 210.A OG1 TRP 206.A O no hydrogen 2.817 N/A THR 210.A OG1 GLU 207.A O no hydrogen 3.193 N/A PHE 211.A N LEU 208.A O no hydrogen 3.002 N/A GLY 212.A N GLU 207.A O no hydrogen 2.705 N/A SER 213.A N THR 210.A OG1 no hydrogen 3.174 N/A ILE 219.A N TYR 216.A O no hydrogen 2.885 N/A SER 222.A OG GLU 223.A OE1 no hydrogen 3.484 N/A GLU 223.A N GLU 223.A OE1 no hydrogen 2.542 N/A ILE 224.A N ALA 221.A O no hydrogen 3.237 N/A ILE 227.A N GLU 223.A O no hydrogen 2.755 N/A LEU 228.A N ILE 224.A O no hydrogen 2.822 N/A GLU 229.A N SER 225.A O no hydrogen 3.049 N/A LYS 230.A N SER 226.A O no hydrogen 3.024 N/A GLY 231.A N LEU 228.A O no hydrogen 3.015 N/A GLU 232.A N ILE 227.A O no hydrogen 3.291 N/A ARG 233.A NE TRP 252.A O no hydrogen 3.136 N/A ARG 233.A NH1 LEU 228.A O no hydrogen 2.996 N/A ARG 233.A NH1 GLU 232.A O no hydrogen 2.945 N/A ARG 233.A NH2 TRP 252.A O no hydrogen 2.769 N/A GLN 236.A NE2 CYS 240.A O no hydrogen 3.109 N/A CYS 240.A N PRO 237.A O no hydrogen 3.011 N/A THR 241.A N TYR 279.A O no hydrogen 3.259 N/A THR 241.A OG1 TYR 279.A O no hydrogen 2.710 N/A VAL 244.A N THR 241.A O no hydrogen 3.012 N/A TYR 245.A N THR 241.A O no hydrogen 3.105 N/A TYR 245.A OH LEU 234.A O no hydrogen 2.582 N/A MET 246.A N ILE 242.A O no hydrogen 2.832 N/A MET 248.A N VAL 244.A O no hydrogen 3.273 N/A VAL 249.A N TYR 245.A O no hydrogen 2.869 N/A LYS 250.A N MET 246.A O no hydrogen 2.939 N/A CYS 251.A N ILE 247.A O no hydrogen 3.177 N/A CYS 251.A SG ILE 247.A O no hydrogen 3.484 N/A TRP 252.A N VAL 249.A O no hydrogen 2.965 N/A MET 253.A N LYS 250.A O no hydrogen 3.401 N/A SER 258.A N ASP 255.A O no hydrogen 2.855 N/A SER 258.A OG ASP 255.A OD2 no hydrogen 2.842 N/A ARG 259.A N ALA 256.A O no hydrogen 3.217 N/A ARG 259.A NE MET 253.A O no hydrogen 3.036 N/A ARG 259.A NH1 GLU 185.A OE2 no hydrogen 2.985 N/A ARG 259.A NH1 GLN 195.A O no hydrogen 2.998 N/A ARG 259.A NH2 GLU 185.A OE1 no hydrogen 2.854 N/A ARG 259.A NH2 GLU 185.A OE2 no hydrogen 3.562 N/A ARG 259.A NH2 MET 253.A O no hydrogen 3.020 N/A LYS 261.A N GLU 264.A OE1 no hydrogen 3.036 N/A GLU 264.A N LYS 261.A O no hydrogen 2.811 N/A LEU 265.A N LYS 261.A O no hydrogen 2.864 N/A ILE 266.A N PHE 262.A O no hydrogen 2.893 N/A ILE 267.A N ARG 263.A O no hydrogen 3.452 N/A GLU 268.A N GLU 264.A O no hydrogen 2.962 N/A PHE 269.A N LEU 265.A O no hydrogen 3.127 N/A SER 270.A N ILE 266.A O no hydrogen 2.887 N/A LYS 271.A N ILE 267.A O no hydrogen 2.964 N/A LYS 271.A NZ GLU 268.A OE2 no hydrogen 3.373 N/A MET 272.A N GLU 268.A O no hydrogen 3.012 N/A ALA 273.A N PHE 269.A O no hydrogen 2.775 N/A ARG 274.A N LYS 271.A O no hydrogen 3.223 N/A ASP 275.A N MET 272.A O no hydrogen 3.108 N/A ARG 278.A N ASP 275.A O no hydrogen 3.000 N/A TYR 279.A N PRO 276.A O no hydrogen 3.080 N/A LEU 280.A N PRO 276.A O no hydrogen 3.055 N/A VAL 281.A N ILE 239.A O no hydrogen 2.908 N/A ASP 285.A N ILE 282.A O no hydrogen 3.272 N/A ARG 287.A N GLY 284.A O no hydrogen 3.256 N/A MET 288.A N ASP 285.A O no hydrogen 3.342 N/A VAL 293.A N LYS 44.A O no hydrogen 2.883 N/A ASP 296.A N ASP 294.A OD2 no hydrogen 2.921 N/A GLU 297.A N ASP 294.A O no hydrogen 2.764 N/A TYR 298.A N ALA 295.A O no hydrogen 2.951 N/A TYR 298.A OH GLU 41.A OE2 no hydrogen 2.535 N/A