Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7l6x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N ASP 2.A OD1 no hydrogen 3.076 N/A VAL 5.A N ASP 2.A O no hydrogen 3.235 N/A LEU 7.A N PRO 3.A O no hydrogen 2.903 N/A SER 8.A N MET 4.A O no hydrogen 2.853 N/A SER 8.A OG MET 4.A O no hydrogen 2.973 N/A SER 8.A OG VAL 56.A O no hydrogen 3.312 N/A SER 9.A N VAL 5.A O no hydrogen 2.893 N/A ILE 10.A N THR 6.A O no hydrogen 2.992 N/A LEU 11.A N LEU 7.A O no hydrogen 3.033 N/A GLU 12.A N SER 8.A O no hydrogen 2.882 N/A SER 13.A N SER 9.A O no hydrogen 2.854 N/A ILE 14.A N ILE 10.A O no hydrogen 3.001 N/A ILE 15.A N LEU 11.A O no hydrogen 2.905 N/A ASN 16.A N GLU 12.A O no hydrogen 2.941 N/A ASP 17.A N SER 13.A O no hydrogen 3.017 N/A MET 18.A N ILE 14.A O no hydrogen 2.895 N/A ARG 19.A N ILE 15.A O no hydrogen 2.834 N/A ARG 19.A NE ASP 20.A OD1 no hydrogen 3.346 N/A ASP 20.A N ASN 16.A O no hydrogen 3.152 N/A LEU 21.A N MET 18.A O no hydrogen 3.132 N/A THR 24.A OG1 ARG 19.A O no hydrogen 3.067 N/A THR 24.A OG1 LEU 21.A O no hydrogen 3.391 N/A THR 24.A OG1 HIS 28.A NE2 no hydrogen 2.631 N/A PHE 27.A N THR 24.A O no hydrogen 3.206 N/A HIS 28.A N TYR 25.A O no hydrogen 3.148 N/A HIS 28.A NE2 THR 24.A OG1 no hydrogen 2.631 N/A VAL 35.A N ASN 32.A O no hydrogen 3.021 N/A VAL 36.A N ASN 32.A O no hydrogen 3.141 N/A TYR 39.A N VAL 36.A O no hydrogen 3.378 N/A LYS 41.A N ASP 38.A O no hydrogen 3.179 N/A ILE 42.A N TYR 39.A O no hydrogen 3.323 N/A ILE 43.A N TYR 39.A O no hydrogen 3.363 N/A LEU 49.A N PHE 27.A O no hydrogen 3.166 N/A GLN 50.A N HIS 28.A O no hydrogen 3.214 N/A THR 51.A N ASP 48.A OD2 no hydrogen 2.735 N/A THR 51.A OG1 ASP 48.A O no hydrogen 3.196 N/A THR 51.A OG1 ASP 48.A OD1 no hydrogen 2.479 N/A LEU 52.A N ASP 48.A O no hydrogen 3.001 N/A ARG 53.A N LEU 49.A O no hydrogen 2.840 N/A ARG 53.A NH2 ASN 16.A OD1 no hydrogen 2.857 N/A GLU 54.A N GLN 50.A O no hydrogen 2.824 N/A ASN 55.A N THR 51.A O no hydrogen 2.807 N/A ASN 55.A ND2 TYR 61.A OH no hydrogen 2.822 N/A VAL 56.A N LEU 52.A O no hydrogen 2.906 N/A ARG 57.A N ARG 53.A O no hydrogen 2.924 N/A LYS 58.A N GLU 54.A O no hydrogen 2.962 N/A LYS 58.A NZ GLU 54.A OE2 no hydrogen 2.680 N/A ARG 59.A N VAL 56.A O no hydrogen 2.912 N/A LEU 60.A N ASN 55.A O no hydrogen 2.984 N/A TYR 61.A OH HIS 70.A ND1 no hydrogen 2.686 N/A SER 63.A OG GLU 66.A OE1 no hydrogen 2.479 N/A ARG 64.A N GLU 114.A OE2 no hydrogen 2.990 N/A ARG 64.A NH2 GLU 107.A O no hydrogen 3.235 N/A GLU 65.A N SER 63.A OG no hydrogen 3.201 N/A GLU 66.A N GLU 66.A OE1 no hydrogen 2.877 N/A ARG 68.A N ARG 64.A O no hydrogen 2.845 N/A ARG 68.A NE ASP 100.A OD1 no hydrogen 2.701 N/A ARG 68.A NH2 ASP 100.A OD1 no hydrogen 2.714 N/A ARG 68.A NH2 ASP 100.A OD2 no hydrogen 2.794 N/A GLU 69.A N GLU 65.A O no hydrogen 2.737 N/A HIS 70.A N GLU 66.A O no hydrogen 3.052 N/A HIS 70.A ND1 TYR 61.A OH no hydrogen 2.686 N/A LEU 71.A N PHE 67.A O no hydrogen 2.846 N/A GLU 72.A N ARG 68.A O no hydrogen 2.767 N/A LEU 73.A N GLU 69.A O no hydrogen 3.055 N/A LEU 73.A N HIS 70.A O no hydrogen 3.190 N/A ILE 74.A N LEU 71.A O no hydrogen 3.145 N/A LYS 76.A N GLU 72.A O no hydrogen 3.050 N/A ASN 77.A N LEU 73.A O no hydrogen 2.760 N/A ASN 77.A ND2 ARG 45.A O no hydrogen 3.041 N/A SER 78.A N ILE 74.A O no hydrogen 2.922 N/A SER 78.A OG VAL 75.A O no hydrogen 2.869 N/A SER 78.A OG SER 92.A OG no hydrogen 3.187 N/A ALA 79.A N VAL 75.A O no hydrogen 2.899 N/A THR 80.A N LYS 76.A O no hydrogen 2.877 N/A THR 80.A OG1 LYS 76.A O no hydrogen 2.948 N/A TYR 81.A N ASN 77.A O no hydrogen 2.840 N/A ASN 82.A N SER 78.A O no hydrogen 2.506 N/A GLY 83.A N SER 78.A O no hydrogen 3.238 N/A HIS 86.A N GLY 83.A O no hydrogen 3.271 N/A LEU 88.A N HIS 86.A ND1 no hydrogen 2.867 N/A THR 89.A OG1 GLY 83.A O no hydrogen 3.399 N/A THR 89.A OG1 PRO 84.A O no hydrogen 3.226 N/A THR 89.A OG1 HIS 86.A O no hydrogen 2.564 N/A GLN 90.A N HIS 86.A O no hydrogen 2.968 N/A ILE 91.A N SER 87.A O no hydrogen 2.727 N/A SER 92.A N LEU 88.A O no hydrogen 2.801 N/A SER 92.A OG SER 78.A OG no hydrogen 3.187 N/A SER 92.A OG LEU 88.A O no hydrogen 3.237 N/A SER 92.A OG THR 89.A O no hydrogen 2.722 N/A GLN 93.A N THR 89.A O no hydrogen 2.861 N/A SER 94.A N GLN 90.A O no hydrogen 2.874 N/A SER 94.A OG ILE 91.A O no hydrogen 2.511 N/A MET 95.A N ILE 91.A O no hydrogen 3.168 N/A LEU 96.A N SER 92.A O no hydrogen 3.169 N/A ASP 97.A N GLN 93.A O no hydrogen 2.814 N/A LEU 98.A N SER 94.A O no hydrogen 3.117 N/A CYS 99.A N MET 95.A O no hydrogen 2.887 N/A ASP 100.A N LEU 96.A O no hydrogen 2.879 N/A GLU 101.A N ASP 97.A O no hydrogen 2.946 N/A LYS 102.A N LEU 98.A O no hydrogen 2.904 N/A LYS 102.A NZ GLU 105.A OE1 no hydrogen 2.451 N/A LEU 103.A N CYS 99.A O no hydrogen 2.902 N/A LYS 104.A N ASP 100.A O no hydrogen 2.893 N/A LYS 104.A NZ LYS 104.A O no hydrogen 3.289 N/A LYS 104.A NZ GLU 107.A OE2 no hydrogen 2.719 N/A GLU 105.A N GLU 101.A O no hydrogen 2.911 N/A LYS 106.A N LYS 102.A O no hydrogen 3.017 N/A GLU 107.A N LYS 104.A O no hydrogen 3.374 N/A LEU 110.A N LYS 106.A O no hydrogen 2.919 N/A ALA 111.A N GLU 107.A O no hydrogen 2.858 N/A ARG 112.A N ASP 108.A O no hydrogen 3.017 N/A LEU 113.A N LYS 109.A O no hydrogen 2.921 N/A GLU 114.A N LEU 110.A O no hydrogen 2.824 N/A LYS 115.A N ALA 111.A O no hydrogen 3.023 N/A ALA 116.A N ARG 112.A O no hydrogen 2.997 N/A ILE 117.A N LEU 113.A O no hydrogen 2.827 N/A ASN 118.A N GLU 114.A O no hydrogen 3.046 N/A LEU 120.A N ASN 118.A OD1 no hydrogen 3.114 N/A LEU 121.A N ASN 118.A O no hydrogen 3.178 N/A ASP 122.A N PRO 119.A O no hydrogen 2.924 N/A ASP 123.A N LEU 120.A O no hydrogen 2.953 N/A GLN 126.A NE2 GLN 126.A O no hydrogen 3.150 N/A GLN 126.A NE2 SER 130.A OG no hydrogen 3.221 N/A GLN 126.A NE2 TYR 184.A O no hydrogen 3.063 N/A VAL 127.A N ASP 123.A O no hydrogen 2.935 N/A ALA 128.A N ASP 124.A O no hydrogen 3.133 N/A PHE 129.A N ASP 125.A O no hydrogen 2.898 N/A SER 130.A N GLN 126.A O no hydrogen 2.934 N/A SER 130.A OG GLN 126.A O no hydrogen 3.225 N/A SER 130.A OG ILE 179.A O no hydrogen 3.527 N/A SER 130.A OG HIS 182.A ND1 no hydrogen 2.621 N/A PHE 131.A N VAL 127.A O no hydrogen 2.794 N/A ILE 132.A N ALA 128.A O no hydrogen 2.945 N/A LEU 133.A N PHE 129.A O no hydrogen 2.998 N/A ASP 134.A N SER 130.A O no hydrogen 2.816 N/A ASN 135.A N PHE 131.A O no hydrogen 2.974 N/A ILE 136.A N ILE 132.A O no hydrogen 2.970 N/A VAL 137.A N LEU 133.A O no hydrogen 3.032 N/A THR 138.A N ASP 134.A O no hydrogen 2.870 N/A THR 138.A OG1 ASP 134.A O no hydrogen 3.330 N/A THR 138.A OG1 GLN 139.A OE1 no hydrogen 2.984 N/A GLN 139.A N ASN 135.A O no hydrogen 2.719 N/A LYS 140.A N ILE 136.A O no hydrogen 3.036 N/A MET 141.A N ILE 136.A O no hydrogen 2.871 N/A MET 142.A N VAL 137.A O no hydrogen 2.797 N/A ALA 143.A N LYS 140.A O no hydrogen 3.293 N/A VAL 144.A N MET 141.A O no hydrogen 2.971 N/A SER 147.A N VAL 144.A O no hydrogen 3.037 N/A SER 147.A OG MET 142.A O no hydrogen 2.818 N/A SER 147.A OG VAL 144.A O no hydrogen 2.674 N/A SER 147.A OG HIS 151.A NE2 no hydrogen 2.983 N/A PHE 150.A N SER 147.A O no hydrogen 2.985 N/A HIS 151.A N TRP 148.A O no hydrogen 3.135 N/A HIS 151.A NE2 SER 147.A OG no hydrogen 2.983 N/A HIS 152.A ND1 GLU 173.A OE1 no hydrogen 2.654 N/A LYS 157.A N ASN 155.A OD1 no hydrogen 2.761 N/A PHE 158.A N ASN 155.A O no hydrogen 2.836 N/A VAL 159.A N ASN 155.A O no hydrogen 3.388 N/A TYR 162.A N VAL 159.A O no hydrogen 3.155 N/A TYR 163.A OH VAL 154.A O no hydrogen 2.577 N/A LYS 164.A N ASP 161.A O no hydrogen 3.102 N/A VAL 165.A N ASP 161.A O no hydrogen 3.376 N/A VAL 165.A N TYR 162.A O no hydrogen 3.040 N/A ILE 166.A N TYR 162.A O no hydrogen 2.835 N/A LEU 172.A N PHE 150.A O no hydrogen 2.791 N/A GLU 173.A N HIS 151.A O no hydrogen 3.131 N/A THR 174.A N ASP 171.A OD2 no hydrogen 2.675 N/A THR 174.A OG1 ASP 171.A OD1 no hydrogen 2.611 N/A THR 174.A OG1 ASP 171.A OD2 no hydrogen 3.229 N/A ILE 175.A N ASP 171.A O no hydrogen 3.133 N/A ARG 176.A N LEU 172.A O no hydrogen 2.937 N/A ARG 176.A NE ASP 134.A OD1 no hydrogen 2.880 N/A ARG 176.A NH2 ASP 134.A OD1 no hydrogen 3.531 N/A ARG 176.A NH2 ASP 134.A OD2 no hydrogen 2.958 N/A LYS 177.A N GLU 173.A O no hydrogen 2.917 N/A ASN 178.A N THR 174.A O no hydrogen 2.829 N/A ASN 178.A ND2 TYR 184.A OH no hydrogen 3.270 N/A ILE 179.A N ILE 175.A O no hydrogen 2.779 N/A SER 180.A N ARG 176.A O no hydrogen 2.839 N/A SER 180.A OG LYS 177.A O no hydrogen 2.941 N/A LYS 181.A N LYS 177.A O no hydrogen 3.102 N/A HIS 182.A N ILE 179.A O no hydrogen 2.761 N/A HIS 182.A ND1 SER 130.A OG no hydrogen 2.621 N/A LYS 183.A N ASN 178.A O no hydrogen 2.995 N/A LYS 183.A NZ ASP 193.A OD2 no hydrogen 3.476 N/A TYR 184.A OH ASP 193.A OD2 no hydrogen 2.434 N/A GLN 185.A NE2 GLN 126.A OE1 no hydrogen 3.553 N/A GLN 185.A NE2 LYS 183.A O no hydrogen 3.605 N/A ARG 187.A N GLU 237.A OE2 no hydrogen 2.892 N/A ARG 187.A NE GLU 237.A OE2 no hydrogen 2.655 N/A ARG 187.A NH1 ASP 230.A OD1 no hydrogen 2.733 N/A ARG 187.A NH2 THR 234.A OG1 no hydrogen 2.857 N/A ARG 187.A NH2 GLU 237.A OE1 no hydrogen 2.725 N/A GLU 188.A N SER 186.A OG no hydrogen 3.200 N/A SER 189.A OG SER 186.A O no hydrogen 3.179 N/A LEU 191.A N ARG 187.A O no hydrogen 2.867 N/A ASP 192.A N GLU 188.A O no hydrogen 2.897 N/A ASP 193.A N SER 189.A O no hydrogen 3.192 N/A VAL 194.A N PHE 190.A O no hydrogen 2.987 N/A ASN 195.A N LEU 191.A O no hydrogen 2.769 N/A LEU 196.A N ASP 192.A O no hydrogen 3.050 N/A ILE 197.A N ASP 193.A O no hydrogen 3.268 N/A ILE 197.A N VAL 194.A O no hydrogen 3.064 N/A ALA 199.A N ASN 195.A O no hydrogen 2.942 N/A ASN 200.A N LEU 196.A O no hydrogen 2.872 N/A ASN 200.A ND2 ASN 168.A O no hydrogen 3.015 N/A SER 201.A N ILE 197.A O no hydrogen 2.986 N/A VAL 202.A N LEU 198.A O no hydrogen 3.048 N/A LYS 203.A N ALA 199.A O no hydrogen 3.003 N/A TYR 204.A N ASN 200.A O no hydrogen 2.927 N/A TYR 204.A OH ASP 161.A OD1 no hydrogen 2.471 N/A ASN 205.A N SER 201.A O no hydrogen 2.821 N/A ASN 205.A ND2 SER 201.A O no hydrogen 3.491 N/A ASN 205.A ND2 SER 201.A OG no hydrogen 3.035 N/A GLY 206.A N VAL 202.A O no hydrogen 2.942 N/A SER 209.A N GLY 206.A O no hydrogen 3.242 N/A TYR 211.A N SER 209.A OG no hydrogen 2.882 N/A THR 212.A OG1 PRO 207.A O no hydrogen 3.107 N/A THR 212.A OG1 SER 209.A O no hydrogen 2.773 N/A LYS 213.A N SER 209.A O no hydrogen 3.002 N/A LYS 213.A NZ GLU 208.A OE1 no hydrogen 3.365 N/A THR 214.A N GLN 210.A O no hydrogen 3.045 N/A THR 214.A OG1 GLN 210.A O no hydrogen 3.398 N/A THR 214.A OG1 GLN 210.A OE1 no hydrogen 3.364 N/A ALA 215.A N TYR 211.A O no hydrogen 2.854 N/A GLN 216.A N THR 212.A O no hydrogen 2.788 N/A GLN 216.A NE2 ASN 220.A OD1 no hydrogen 2.500 N/A GLU 217.A N LYS 213.A O no hydrogen 3.014 N/A ILE 218.A N THR 214.A O no hydrogen 2.894 N/A VAL 219.A N ALA 215.A O no hydrogen 2.960 N/A ASN 220.A N GLN 216.A O no hydrogen 2.864 N/A VAL 221.A N GLU 217.A O no hydrogen 2.969 N/A CYS 222.A N ILE 218.A O no hydrogen 3.017 N/A TYR 223.A N VAL 219.A O no hydrogen 2.889 N/A TYR 223.A OH ASN 195.A OD1 no hydrogen 2.753 N/A GLN 224.A N ASN 220.A O no hydrogen 2.843 N/A THR 225.A N VAL 221.A O no hydrogen 2.956 N/A THR 225.A OG1 VAL 221.A O no hydrogen 2.847 N/A LEU 226.A N CYS 222.A O no hydrogen 2.887 N/A THR 227.A N TYR 223.A O no hydrogen 2.836 N/A THR 227.A OG1 TYR 223.A O no hydrogen 2.983 N/A GLU 228.A N GLN 224.A O no hydrogen 2.982 N/A TYR 229.A N THR 225.A O no hydrogen 2.919 N/A ASP 230.A N THR 227.A O no hydrogen 3.014 N/A LEU 233.A N TYR 229.A O no hydrogen 3.009 N/A THR 234.A N ASP 230.A O no hydrogen 2.930 N/A THR 234.A OG1 ASP 230.A O no hydrogen 2.806 N/A THR 234.A OG1 ASP 230.A OD1 no hydrogen 3.331 N/A GLN 235.A N GLU 231.A O no hydrogen 3.132 N/A GLN 235.A NE2 ASP 239.A OD2 no hydrogen 3.361 N/A LEU 236.A N HIS 232.A O no hydrogen 2.943 N/A GLU 237.A N LEU 233.A O no hydrogen 2.832 N/A LYS 238.A N THR 234.A O no hydrogen 3.027 N/A ASP 239.A N GLN 235.A O no hydrogen 2.991 N/A ILE 240.A N LEU 236.A O no hydrogen 2.919 N/A CYS 241.A N GLU 237.A O no hydrogen 2.834 N/A THR 242.A N LYS 238.A O no hydrogen 3.027 N/A THR 242.A OG1 ASP 239.A O no hydrogen 2.919 N/A ALA 243.A N ASP 239.A O no hydrogen 2.951 N/A LYS 244.A N ILE 240.A O no hydrogen 2.886 N/A LYS 244.A NZ GLN 185.A OE1 no hydrogen 3.153 N/A GLU 245.A N CYS 241.A O no hydrogen 2.990 N/A ALA 246.A N THR 242.A O no hydrogen 2.971 N/A ALA 247.A N ALA 243.A O no hydrogen 2.896 N/A GLU 249.A N GLU 245.A O no hydrogen 3.205 N/A GLU 250.A N ALA 246.A O no hydrogen 2.945 N/A ALA 251.A N LEU 248.A O no hydrogen 2.947 N/A GLU 252.A N LEU 248.A O no hydrogen 2.913 N/A GLU 254.A N ALA 251.A O no hydrogen 3.278 N/A SER 255.A OG GLU 252.A O no hydrogen 3.169 N/A