Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7m0e_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 4.A N SER 278.A OG no hydrogen 3.047 N/A CYS 4.A SG SER 278.A OG no hydrogen 3.318 N/A ALA 5.A N TRP 2.A O no hydrogen 3.013 N/A GLN 6.A N VAL 3.A O no hydrogen 3.122 N/A SER 8.A N GLU 323.A O no hydrogen 3.091 N/A SER 9.A N GLU 323.A OE1 no hydrogen 2.893 N/A SER 9.A OG GLU 323.A OE1 no hydrogen 2.789 N/A SER 9.A OG GLU 323.A OE2 no hydrogen 2.746 N/A GLN 10.A N PRO 7.A O no hydrogen 3.337 N/A LYS 11.A N SER 8.A O no hydrogen 2.961 N/A LYS 11.A NZ ASN 47.A OD1 no hydrogen 3.033 N/A LYS 11.A NZ ASP 325.A O no hydrogen 3.045 N/A LYS 11.A NZ TRP 326.A O no hydrogen 2.672 N/A ALA 12.A N SER 9.A O no hydrogen 3.005 N/A ASN 14.A ND2 THR 20.A OG1 no hydrogen 3.377 N/A HIS 15.A ND1 PHE 52.A O no hydrogen 3.260 N/A ASN 16.A N ASN 14.A OD1 no hydrogen 2.959 N/A ASN 16.A ND2 LYS 54.A O no hydrogen 3.079 N/A ILE 19.A N ASN 16.A O no hydrogen 3.161 N/A THR 20.A N ASN 16.A O no hydrogen 3.093 N/A THR 20.A OG1 ASN 16.A O no hydrogen 3.524 N/A THR 20.A OG1 LEU 17.A O no hydrogen 3.009 N/A GLU 21.A N LEU 17.A O no hydrogen 2.925 N/A LYS 22.A NZ GLY 83.A O no hydrogen 3.550 N/A LEU 23.A N ILE 19.A O no hydrogen 3.140 N/A GLU 24.A N THR 20.A O no hydrogen 2.821 N/A VAL 25.A N GLU 21.A O no hydrogen 3.381 N/A LEU 26.A N LYS 22.A O no hydrogen 3.441 N/A ALA 27.A N LEU 23.A O no hydrogen 2.860 N/A LYS 28.A N GLU 24.A O no hydrogen 2.952 N/A ALA 29.A N VAL 25.A O no hydrogen 3.085 N/A TYR 30.A N LEU 26.A O no hydrogen 3.021 N/A SER 31.A N ALA 27.A O no hydrogen 3.002 N/A SER 31.A OG ALA 27.A O no hydrogen 3.536 N/A VAL 32.A N LYS 28.A O no hydrogen 3.118 N/A GLN 33.A N ALA 29.A O no hydrogen 3.341 N/A GLY 34.A N SER 31.A O no hydrogen 2.695 N/A ASP 35.A N TYR 30.A O no hydrogen 3.088 N/A LYS 36.A N GLY 34.A O no hydrogen 2.870 N/A ARG 38.A N ASP 35.A OD1 no hydrogen 3.373 N/A ARG 38.A NE ASP 35.A OD2 no hydrogen 2.604 N/A ALA 39.A N ASP 35.A O no hydrogen 2.976 N/A LEU 40.A N LYS 36.A O no hydrogen 2.828 N/A GLY 41.A N TRP 37.A O no hydrogen 3.129 N/A TYR 42.A N ARG 38.A O no hydrogen 3.129 N/A ALA 43.A N ALA 39.A O no hydrogen 2.944 N/A LYS 44.A N LEU 40.A O no hydrogen 2.957 N/A ALA 45.A N GLY 41.A O no hydrogen 2.981 N/A ILE 46.A N TYR 42.A O no hydrogen 2.888 N/A ASN 47.A N ALA 43.A O no hydrogen 3.138 N/A ASN 47.A ND2 TRP 326.A O no hydrogen 3.214 N/A ALA 48.A N LYS 44.A O no hydrogen 3.076 N/A LEU 49.A N ALA 45.A O no hydrogen 2.838 N/A LYS 50.A N ILE 46.A O no hydrogen 2.777 N/A SER 51.A N ASN 47.A O no hydrogen 3.136 N/A SER 51.A OG ASN 47.A O no hydrogen 2.745 N/A SER 51.A OG ALA 48.A O no hydrogen 3.408 N/A PHE 52.A N ALA 48.A O no hydrogen 3.156 N/A PHE 52.A N LEU 49.A O no hydrogen 3.289 N/A LYS 54.A NZ GLU 61.A OE1 no hydrogen 3.552 N/A LYS 54.A NZ GLU 61.A OE2 no hydrogen 2.683 N/A VAL 56.A N ASN 16.A OD1 no hydrogen 2.808 N/A GLU 61.A N SER 58.A OG no hydrogen 3.150 N/A ALA 62.A N SER 58.A O no hydrogen 2.955 N/A CYS 63.A N TYR 59.A O no hydrogen 3.028 N/A CYS 63.A SG TYR 59.A O no hydrogen 3.715 N/A CYS 63.A SG GLY 69.A O no hydrogen 3.864 N/A SER 64.A N GLN 60.A O no hydrogen 3.191 N/A SER 64.A N GLU 61.A O no hydrogen 3.133 N/A SER 64.A OG GLU 61.A O no hydrogen 2.699 N/A ILE 65.A N ALA 62.A O no hydrogen 3.183 N/A ILE 68.A N ILE 65.A O no hydrogen 2.979 N/A ALA 73.A N GLY 69.A O no hydrogen 2.830 N/A GLU 74.A N LYS 70.A O no hydrogen 2.984 N/A LYS 75.A N ARG 71.A O no hydrogen 3.357 N/A LYS 75.A NZ ARG 71.A O no hydrogen 3.565 N/A ILE 76.A N MET 72.A O no hydrogen 2.943 N/A ILE 77.A N ALA 73.A O no hydrogen 3.092 N/A GLU 78.A N GLU 74.A O no hydrogen 3.001 N/A ILE 79.A N LYS 75.A O no hydrogen 3.058 N/A LEU 80.A N ILE 76.A O no hydrogen 2.882 N/A GLU 81.A N ILE 77.A O no hydrogen 2.907 N/A SER 82.A N GLU 78.A O no hydrogen 2.937 N/A SER 82.A OG GLU 78.A O no hydrogen 2.624 N/A GLY 83.A N ILE 79.A O no hydrogen 2.826 N/A HIS 84.A N SER 82.A OG no hydrogen 3.248 N/A HIS 84.A NE2 ASP 89.A OD2 no hydrogen 2.554 N/A ARG 86.A N GLU 78.A OE2 no hydrogen 2.989 N/A LEU 88.A N LEU 85.A O no hydrogen 3.126 N/A ASP 89.A N ARG 86.A O no hydrogen 2.973 N/A HIS 90.A N LYS 87.A O no hydrogen 3.341 N/A SER 92.A OG.A SER 94.A OG no hydrogen 3.141 N/A SER 94.A N SER 92.A OG.A no hydrogen 3.329 N/A SER 94.A OG SER 92.A OG.A no hydrogen 3.141 N/A VAL 95.A N SER 92.A O.A no hydrogen 3.276 N/A VAL 95.A N SER 92.A O.B no hydrogen 3.242 N/A LEU 98.A N SER 94.A O no hydrogen 2.917 N/A GLU 99.A N VAL 95.A O no hydrogen 2.826 N/A LEU 100.A N PRO 96.A O no hydrogen 2.949 N/A PHE 101.A N VAL 97.A O no hydrogen 2.865 N/A SER 102.A N LEU 98.A O no hydrogen 2.930 N/A SER 102.A OG LEU 98.A O no hydrogen 2.871 N/A SER 102.A OG GLU 99.A O no hydrogen 3.399 N/A ASN 103.A N GLU 99.A O no hydrogen 2.986 N/A ASN 103.A N LEU 100.A O no hydrogen 3.355 N/A ASN 103.A ND2 TYR 143.A OH no hydrogen 3.185 N/A ILE 104.A N PHE 101.A O no hydrogen 3.021 N/A ALA 107.A N ILE 104.A O no hydrogen 3.088 N/A THR 109.A OG1 VAL 32.A O no hydrogen 3.510 N/A ALA 112.A N GLY 108.A O no hydrogen 2.926 N/A GLN 113.A N THR 109.A O no hydrogen 2.973 N/A MET 114.A N LYS 110.A O no hydrogen 2.927 N/A TRP 115.A N THR 111.A O no hydrogen 2.956 N/A TYR 116.A N ALA 112.A O no hydrogen 2.972 N/A GLN 117.A N GLN 113.A O no hydrogen 3.016 N/A GLN 118.A N MET 114.A O no hydrogen 3.118 N/A GLN 118.A N TRP 115.A O no hydrogen 3.224 N/A GLN 118.A NE2 MET 114.A O no hydrogen 3.697 N/A GLY 119.A N TYR 116.A O no hydrogen 2.992 N/A PHE 120.A N TRP 115.A O no hydrogen 3.109 N/A ARG 121.A N ASP 125.A OD2 no hydrogen 2.984 N/A ARG 121.A NH1 TYR 116.A O no hydrogen 2.917 N/A ARG 121.A NH1 PHE 120.A O no hydrogen 2.782 N/A SER 122.A N ASP 125.A OD2 no hydrogen 3.341 N/A ASP 125.A N SER 122.A OG no hydrogen 3.277 N/A ILE 126.A N SER 122.A O no hydrogen 3.316 N/A ARG 127.A N LEU 123.A O no hydrogen 2.835 N/A ARG 127.A NE GLU 124.A OE2 no hydrogen 2.944 N/A SER 128.A N GLU 124.A O no hydrogen 3.155 N/A SER 128.A OG GLU 124.A O no hydrogen 2.909 N/A GLN 129.A N ASP 125.A O no hydrogen 2.881 N/A ALA 130.A N ILE 126.A O no hydrogen 3.137 N/A THR 133.A N GLN 136.A OE1 no hydrogen 3.171 N/A GLN 136.A N THR 133.A OG1 no hydrogen 3.093 N/A GLN 136.A NE2 GLY 106.A O no hydrogen 2.905 N/A ALA 137.A N THR 133.A O no hydrogen 2.890 N/A ILE 138.A N THR 134.A O no hydrogen 3.147 N/A GLY 139.A N GLN 135.A O no hydrogen 2.841 N/A LEU 140.A N GLN 136.A O no hydrogen 2.773 N/A LYS 141.A N ALA 137.A O no hydrogen 3.127 N/A HIS 142.A N ILE 138.A O no hydrogen 3.191 N/A HIS 142.A NE2 ASP 222.A OD2 no hydrogen 3.233 N/A TYR 143.A N LEU 140.A O no hydrogen 3.182 N/A PHE 146.A N HIS 142.A O no hydrogen 2.910 N/A GLU 148.A N ASP 145.A O no hydrogen 3.063 N/A ARG 149.A NE THR 187.A OG1 no hydrogen 2.838 N/A ARG 149.A NH2 THR 187.A O no hydrogen 3.158 N/A MET 150.A N CYS 188.A O no hydrogen 2.900 N/A ARG 152.A N ALA 186.A O no hydrogen 2.830 N/A ARG 152.A NH1 TYR 181.A O no hydrogen 2.898 N/A ARG 152.A NH1 LYS 185.A O no hydrogen 3.031 N/A ARG 152.A NH2 TYR 181.A O no hydrogen 2.908 N/A GLU 154.A N PRO 151.A O no hydrogen 3.010 N/A ALA 155.A N PRO 151.A O no hydrogen 3.401 N/A THR 156.A N ARG 152.A O no hydrogen 3.130 N/A THR 156.A OG1 ARG 152.A O no hydrogen 3.343 N/A THR 156.A OG1 TYR 181.A OH no hydrogen 2.649 N/A GLU 157.A N GLU 153.A O no hydrogen 3.196 N/A ILE 158.A N GLU 154.A O no hydrogen 2.971 N/A GLU 159.A N ALA 155.A O no hydrogen 2.897 N/A GLN 160.A N THR 156.A O no hydrogen 2.921 N/A GLN 160.A NE2 GLU 159.A OE1 no hydrogen 3.046 N/A THR 161.A N GLU 157.A O no hydrogen 3.044 N/A THR 161.A OG1 GLU 157.A O no hydrogen 2.877 N/A VAL 162.A N ILE 158.A O no hydrogen 3.156 N/A GLN 163.A N GLU 159.A O no hydrogen 2.811 N/A GLN 163.A NE2 GLU 159.A OE2 no hydrogen 2.689 N/A LYS 164.A N GLN 160.A O no hydrogen 2.937 N/A ALA 165.A N THR 161.A O no hydrogen 3.291 N/A ALA 166.A N VAL 162.A O no hydrogen 2.890 N/A GLN 167.A N GLN 163.A O no hydrogen 2.823 N/A GLN 167.A NE2 LEU 173.A O no hydrogen 3.252 N/A ALA 168.A N LYS 164.A O no hydrogen 3.013 N/A PHE 169.A N ALA 166.A O no hydrogen 3.281 N/A ASN 170.A N ALA 166.A O no hydrogen 3.293 N/A GLY 172.A N ASN 170.A OD1 no hydrogen 2.832 N/A LEU 173.A N ASN 170.A O no hydrogen 3.135 N/A LEU 174.A N THR 196.A O no hydrogen 2.858 N/A VAL 176.A N LEU 194.A O no hydrogen 2.883 N/A CYS 178.A N ASP 192.A O no hydrogen 2.689 N/A CYS 178.A SG VAL 176.A O no hydrogen 3.664 N/A GLY 179.A N PHE 269.A O no hydrogen 2.791 N/A TYR 181.A OH THR 156.A OG1 no hydrogen 2.649 N/A ARG 182.A N CYS 178.A O no hydrogen 3.384 N/A ARG 182.A NH1 THR 270.A OG1 no hydrogen 2.752 N/A ARG 182.A NH1 GLU 307.A OE1 no hydrogen 3.569 N/A ARG 182.A NH1 GLU 307.A OE2 no hydrogen 3.083 N/A ARG 182.A NH2 GLU 307.A OE1 no hydrogen 3.141 N/A ARG 183.A N GLY 179.A O no hydrogen 3.157 N/A ARG 183.A NE ASP 325.A OD1 no hydrogen 2.986 N/A ARG 183.A NH1 THR 270.A O no hydrogen 2.753 N/A ARG 183.A NH2 ASP 325.A OD1 no hydrogen 3.146 N/A GLY 184.A N TYR 181.A O no hydrogen 2.980 N/A LYS 185.A N SER 180.A O no hydrogen 3.094 N/A LYS 185.A NZ ASP 325.A OD2 no hydrogen 2.822 N/A CYS 188.A N MET 150.A O no hydrogen 2.900 N/A CYS 188.A SG SER 180.A OG no hydrogen 3.686 N/A VAL 191.A N ARG 251.A O no hydrogen 3.283 N/A VAL 193.A N ASP 253.A O no hydrogen 2.734 N/A LEU 194.A N VAL 176.A O no hydrogen 2.770 N/A ILE 195.A N ILE 255.A O no hydrogen 2.832 N/A THR 196.A N LEU 174.A O no hydrogen 3.020 N/A THR 196.A OG1 VAL 257.A O no hydrogen 2.859 N/A HIS 197.A NE2 ASN 170.A OD1 no hydrogen 2.900 N/A ASP 199.A N HIS 197.A ND1 no hydrogen 3.155 N/A GLY 200.A N HIS 197.A O no hydrogen 3.198 N/A ARG 201.A N ASP 199.A OD1 no hydrogen 2.959 N/A HIS 203.A NE2 ASP 199.A OD2 no hydrogen 2.895 N/A ARG 204.A NH1 GLN 232.A O no hydrogen 3.456 N/A SER 208.A OG GLN 227.A OE1 no hydrogen 3.141 N/A LEU 210.A N ILE 206.A O no hydrogen 2.860 N/A LEU 211.A N PHE 207.A O no hydrogen 3.003 N/A ASP 212.A N SER 208.A O no hydrogen 3.186 N/A SER 213.A N ARG 209.A O no hydrogen 3.000 N/A LEU 214.A N LEU 210.A O no hydrogen 3.009 N/A ARG 215.A N LEU 211.A O no hydrogen 2.974 N/A ARG 215.A NE ASP 223.A OD1 no hydrogen 3.246 N/A ARG 215.A NH2 ASP 223.A OD1 no hydrogen 3.243 N/A ARG 215.A NH2 ASP 223.A OD2 no hydrogen 3.091 N/A GLN 216.A N ASP 212.A O no hydrogen 2.784 N/A GLU 217.A N SER 213.A O no hydrogen 3.219 N/A GLY 218.A N ARG 215.A O no hydrogen 2.941 N/A PHE 219.A N LEU 214.A O no hydrogen 3.037 N/A LEU 220.A N LEU 214.A O no hydrogen 3.082 N/A THR 221.A N VAL 239.A O no hydrogen 2.792 N/A THR 221.A OG1 ASP 222.A OD2 no hydrogen 3.495 N/A THR 221.A OG1 VAL 239.A O no hydrogen 3.168 N/A LEU 224.A N LEU 237.A O no hydrogen 3.022 N/A VAL 225.A N LEU 237.A O no hydrogen 2.951 N/A GLN 227.A NE2 GLN 234.A OE1 no hydrogen 2.918 N/A GLU 228.A N LYS 235.A O no hydrogen 3.124 N/A ASN 230.A N GLN 233.A O no hydrogen 2.873 N/A GLN 233.A N ASN 230.A O no hydrogen 2.873 N/A GLN 233.A NE2 GLU 261.A OE1 no hydrogen 3.081 N/A GLN 233.A NE2 GLU 292.A O no hydrogen 3.175 N/A GLN 234.A N VAL 256.A O no hydrogen 2.823 N/A GLN 234.A NE2 ARG 204.A O no hydrogen 3.528 N/A LYS 235.A N GLU 228.A O no hydrogen 2.998 N/A TYR 236.A N ILE 254.A O no hydrogen 2.818 N/A TYR 236.A OH ASP 223.A OD1 no hydrogen 2.481 N/A LEU 237.A N VAL 225.A O no hydrogen 3.027 N/A GLY 238.A N LEU 252.A O no hydrogen 2.862 N/A VAL 239.A N ASP 222.A O no hydrogen 2.895 N/A CYS 240.A N ARG 250.A O no hydrogen 2.881 N/A CYS 240.A SG ARG 250.A O no hydrogen 3.637 N/A ARG 241.A N PHE 219.A O no hydrogen 3.089 N/A ARG 247.A NE PRO 243.A O no hydrogen 3.476 N/A ARG 248.A NH1 ASP 145.A OD1 no hydrogen 2.895 N/A HIS 249.A N ASP 145.A OD2 no hydrogen 2.905 N/A ARG 250.A N CYS 240.A O no hydrogen 2.802 N/A ARG 250.A NE GLU 154.A OE2 no hydrogen 3.033 N/A ARG 250.A NH2 GLU 154.A OE1 no hydrogen 2.971 N/A ARG 251.A NH2 PHE 146.A O no hydrogen 3.374 N/A LEU 252.A N GLY 238.A O no hydrogen 2.804 N/A ASP 253.A N VAL 191.A O no hydrogen 2.862 N/A ILE 254.A N TYR 236.A O no hydrogen 2.826 N/A ILE 255.A N VAL 193.A O no hydrogen 3.014 N/A VAL 256.A N GLN 234.A O no hydrogen 2.761 N/A VAL 257.A N ILE 195.A O no hydrogen 2.936 N/A GLU 261.A N PRO 258.A O no hydrogen 2.899 N/A PHE 262.A N TYR 259.A O no hydrogen 2.926 N/A CYS 264.A SG THR 304.A OG1 no hydrogen 3.620 N/A ALA 265.A N GLU 261.A O no hydrogen 2.993 N/A LEU 266.A N PHE 262.A O no hydrogen 2.727 N/A LEU 267.A N ALA 263.A O no hydrogen 2.804 N/A TYR 268.A N CYS 264.A O no hydrogen 2.988 N/A PHE 269.A N ALA 265.A O no hydrogen 2.887 N/A THR 270.A N LEU 266.A O no hydrogen 2.963 N/A THR 270.A OG1 LEU 266.A O no hydrogen 2.772 N/A GLY 271.A N LEU 267.A O no hydrogen 3.265 N/A SER 272.A N ARG 324.A O no hydrogen 2.998 N/A SER 272.A OG ARG 324.A O no hydrogen 3.315 N/A SER 272.A OG TRP 326.A OXT no hydrogen 2.486 N/A PHE 275.A N SER 272.A OG no hydrogen 3.167 N/A ASN 276.A N SER 272.A O no hydrogen 2.936 N/A ASN 276.A ND2 TYR 268.A O no hydrogen 2.789 N/A ARG 277.A N ALA 273.A O no hydrogen 3.073 N/A SER 278.A N HIS 274.A O no hydrogen 2.997 N/A MET 279.A N PHE 275.A O no hydrogen 2.856 N/A ARG 280.A N ASN 276.A O no hydrogen 2.743 N/A ARG 280.A NH1 GLU 292.A OE2 no hydrogen 3.101 N/A ARG 280.A NH2 GLU 292.A OE2 no hydrogen 2.857 N/A ALA 281.A N ARG 277.A O no hydrogen 2.922 N/A LEU 282.A N SER 278.A O no hydrogen 3.027 N/A ALA 283.A N MET 279.A O no hydrogen 3.019 N/A LYS 284.A N ARG 280.A O no hydrogen 3.014 N/A THR 285.A N ALA 281.A O no hydrogen 3.082 N/A THR 285.A OG1 LEU 282.A O no hydrogen 2.703 N/A LYS 286.A N LEU 282.A O no hydrogen 3.318 N/A LYS 286.A N ALA 283.A O no hydrogen 3.041 N/A GLY 287.A N LYS 284.A O no hydrogen 3.096 N/A MET 288.A N ALA 283.A O no hydrogen 2.817 N/A SER 289.A N SER 296.A O no hydrogen 2.970 N/A SER 291.A N ALA 294.A O no hydrogen 3.039 N/A HIS 293.A N SER 291.A OG no hydrogen 3.005 N/A HIS 293.A ND1 GLU 261.A OE1 no hydrogen 3.205 N/A HIS 293.A NE2 ASN 230.A OD1 no hydrogen 2.935 N/A SER 296.A N SER 289.A O no hydrogen 2.770 N/A THR 297.A N ARG 300.A O no hydrogen 3.159 N/A ARG 300.A N THR 297.A OG1 no hydrogen 3.132 N/A LEU 302.A N LEU 295.A O no hydrogen 2.890 N/A THR 306.A N ASP 309.A OD2 no hydrogen 3.142 N/A THR 306.A OG1 ASP 309.A OD2 no hydrogen 3.063 N/A ASP 309.A N THR 306.A O no hydrogen 3.023 N/A VAL 310.A N GLU 307.A O no hydrogen 2.954 N/A PHE 311.A N GLU 307.A O no hydrogen 3.236 N/A ARG 312.A N LYS 308.A O no hydrogen 2.886 N/A ARG 312.A NH2 ASP 309.A OD1 no hydrogen 2.690 N/A LEU 313.A N ASP 309.A O no hydrogen 2.874 N/A LEU 314.A N VAL 310.A O no hydrogen 3.061 N/A LEU 314.A N PHE 311.A O no hydrogen 3.191 N/A GLY 315.A N ARG 312.A O no hydrogen 2.781 N/A LEU 316.A N PHE 311.A O no hydrogen 2.805 N/A ARG 319.A NH2 ALA 5.A O no hydrogen 3.090 N/A GLU 323.A N GLU 320.A O no hydrogen 2.803 N/A ARG 324.A N PRO 321.A O no hydrogen 3.036 N/A ARG 324.A NE ARG 319.A O no hydrogen 2.840 N/A ARG 324.A NH1 GLU 307.A OE1 no hydrogen 3.450 N/A ARG 324.A NH1 GLU 307.A OE2 no hydrogen 2.937 N/A ARG 324.A NH2 GLU 307.A OE1 no hydrogen 2.770 N/A ARG 324.A NH2 ARG 319.A O no hydrogen 2.990 N/A ASP 325.A N SER 8.A OG no hydrogen 2.877 N/A TRP 326.A NE1 GLN 6.A O no hydrogen 3.162 N/A