Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7m4i_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A ND2 LYS 40.A O no hydrogen 3.627 N/A ILE 5.A N ASN 2.A O no hydrogen 2.763 N/A THR 6.A N ASN 2.A O no hydrogen 2.918 N/A GLU 7.A N LEU 3.A O no hydrogen 3.079 N/A LEU 9.A N ILE 5.A O no hydrogen 3.302 N/A GLU 10.A N THR 6.A O no hydrogen 2.750 N/A ALA 13.A N LEU 9.A O no hydrogen 2.890 N/A LYS 14.A N GLU 10.A O no hydrogen 2.927 N/A ALA 15.A N VAL 11.A O no hydrogen 2.903 N/A TYR 16.A N LEU 12.A O no hydrogen 2.819 N/A SER 17.A N ALA 13.A O no hydrogen 2.841 N/A VAL 18.A N LYS 14.A O no hydrogen 2.999 N/A GLN 19.A N ALA 15.A O no hydrogen 3.191 N/A GLN 19.A N TYR 16.A O no hydrogen 3.288 N/A GLN 19.A NE2 ALA 15.A O no hydrogen 2.739 N/A GLY 20.A N SER 17.A O no hydrogen 3.244 N/A ASP 21.A N TYR 16.A O no hydrogen 3.124 N/A ARG 24.A N ASP 21.A OD1 no hydrogen 3.324 N/A ALA 25.A N ASP 21.A O no hydrogen 3.015 N/A LEU 26.A N LYS 22.A O no hydrogen 2.860 N/A GLY 27.A N TRP 23.A O no hydrogen 2.936 N/A TYR 28.A N ARG 24.A O no hydrogen 2.983 N/A ALA 29.A N ALA 25.A O no hydrogen 2.970 N/A LYS 30.A N LEU 26.A O no hydrogen 2.929 N/A ALA 31.A N GLY 27.A O no hydrogen 3.021 N/A ILE 32.A N TYR 28.A O no hydrogen 2.818 N/A ASN 33.A N ALA 29.A O no hydrogen 3.102 N/A ALA 34.A N LYS 30.A O no hydrogen 2.924 N/A LEU 35.A N ALA 31.A O no hydrogen 3.013 N/A LEU 35.A N ILE 32.A O no hydrogen 3.226 N/A LYS 36.A N ILE 32.A O no hydrogen 3.379 N/A SER 37.A N ASN 33.A O no hydrogen 3.133 N/A PHE 38.A N LEU 35.A O no hydrogen 3.295 N/A GLU 47.A N SER 44.A OG no hydrogen 3.025 N/A ALA 48.A N SER 44.A O no hydrogen 2.629 N/A CYS 49.A N TYR 45.A O no hydrogen 2.816 N/A SER 50.A N GLU 47.A O no hydrogen 2.760 N/A ILE 51.A N ALA 48.A O no hydrogen 3.131 N/A ILE 54.A N ILE 51.A O no hydrogen 3.401 N/A ALA 59.A N GLY 55.A O no hydrogen 2.763 N/A GLU 60.A N LYS 56.A O no hydrogen 2.929 N/A LYS 61.A N ARG 57.A O no hydrogen 3.158 N/A ILE 62.A N MET 58.A O no hydrogen 2.841 N/A ILE 63.A N ALA 59.A O no hydrogen 2.718 N/A GLU 64.A N GLU 60.A O no hydrogen 2.836 N/A GLU 64.A N LYS 61.A O no hydrogen 3.074 N/A ILE 65.A N LYS 61.A O no hydrogen 3.090 N/A LEU 66.A N ILE 62.A O no hydrogen 3.104 N/A SER 68.A N GLU 64.A O no hydrogen 3.155 N/A GLY 69.A N ILE 65.A O no hydrogen 3.083 N/A HIS 76.A N LYS 73.A O no hydrogen 2.914 N/A SER 78.A OG SER 80.A OG no hydrogen 2.733 N/A SER 80.A N SER 78.A OG no hydrogen 3.059 N/A SER 80.A OG SER 78.A OG no hydrogen 2.733 N/A VAL 81.A N SER 78.A O no hydrogen 3.158 N/A LEU 84.A N SER 80.A O no hydrogen 2.938 N/A GLU 85.A N VAL 81.A O no hydrogen 2.877 N/A LEU 86.A N PRO 82.A O no hydrogen 2.907 N/A PHE 87.A N VAL 83.A O no hydrogen 2.866 N/A SER 88.A N LEU 84.A O no hydrogen 2.807 N/A SER 88.A OG LEU 84.A O no hydrogen 2.847 N/A SER 88.A OG GLU 85.A O no hydrogen 3.347 N/A ASN 89.A N GLU 85.A O no hydrogen 3.067 N/A ILE 90.A N PHE 87.A O no hydrogen 2.978 N/A ALA 93.A N ILE 90.A O no hydrogen 2.988 N/A THR 95.A OG1.A VAL 18.A O no hydrogen 2.913 N/A THR 95.A OG1.B SER 17.A O no hydrogen 3.369 N/A ALA 98.A N GLY 94.A O no hydrogen 2.962 N/A GLN 99.A N THR 95.A O no hydrogen 2.989 N/A MET 100.A N LYS 96.A O no hydrogen 3.157 N/A TRP 101.A N THR 97.A O no hydrogen 3.016 N/A TYR 102.A N ALA 98.A O no hydrogen 3.000 N/A GLN 103.A N GLN 99.A O no hydrogen 2.868 N/A GLN 104.A N MET 100.A O no hydrogen 2.842 N/A GLY 105.A N TYR 102.A O no hydrogen 3.107 N/A PHE 106.A N TRP 101.A O no hydrogen 3.029 N/A ARG 107.A N ASP 111.A OD2 no hydrogen 2.971 N/A ARG 107.A NH1 TYR 102.A O no hydrogen 2.853 N/A ARG 107.A NH1 PHE 106.A O no hydrogen 2.846 N/A ASP 111.A N SER 108.A OG no hydrogen 3.117 N/A ILE 112.A N SER 108.A O no hydrogen 3.085 N/A ARG 113.A N LEU 109.A O no hydrogen 2.826 N/A ARG 113.A NE GLU 110.A OE1 no hydrogen 3.081 N/A ARG 113.A NH2 GLU 110.A OE2 no hydrogen 3.017 N/A SER 114.A N GLU 110.A O no hydrogen 3.005 N/A SER 114.A OG GLU 110.A O no hydrogen 2.989 N/A SER 114.A OG ASP 111.A O no hydrogen 3.349 N/A GLN 115.A N ASP 111.A O no hydrogen 2.942 N/A ALA 116.A N ILE 112.A O no hydrogen 3.014 N/A THR 119.A N GLN 122.A OE1 no hydrogen 2.967 N/A GLN 121.A NE2 LEU 210.A O no hydrogen 2.929 N/A GLN 122.A N THR 119.A OG1 no hydrogen 3.070 N/A GLN 122.A NE2 GLY 92.A O no hydrogen 3.010 N/A ALA 123.A N THR 119.A O no hydrogen 2.952 N/A ILE 124.A N THR 120.A O no hydrogen 3.279 N/A GLY 125.A N GLN 121.A O no hydrogen 2.909 N/A LEU 126.A N GLN 122.A O no hydrogen 2.789 N/A LYS 127.A N ALA 123.A O no hydrogen 3.007 N/A LYS 127.A NZ ASP 208.A OD2 no hydrogen 2.876 N/A HIS 128.A N ILE 124.A O no hydrogen 3.058 N/A HIS 128.A N GLY 125.A O no hydrogen 3.251 N/A HIS 128.A NE2 ASP 208.A OD1 no hydrogen 3.058 N/A TYR 129.A N LEU 126.A O no hydrogen 3.053 N/A TYR 129.A OH LEU 86.A O no hydrogen 2.819 N/A PHE 132.A N HIS 128.A O no hydrogen 2.969 N/A LEU 133.A N SER 130.A O no hydrogen 3.158 N/A GLU 134.A N ASP 131.A O no hydrogen 3.071 N/A ARG 135.A NE THR 173.A OG1 no hydrogen 2.941 N/A ARG 135.A NH2 THR 173.A O no hydrogen 2.831 N/A MET 136.A N CYS 174.A O no hydrogen 2.650 N/A ARG 138.A N ALA 172.A O no hydrogen 2.873 N/A ARG 138.A NH1 TYR 167.A O no hydrogen 2.946 N/A ARG 138.A NH1 LYS 171.A O no hydrogen 2.745 N/A ARG 138.A NH2 TYR 167.A O no hydrogen 3.231 N/A GLU 140.A N PRO 137.A O no hydrogen 2.693 N/A ALA 141.A N PRO 137.A O no hydrogen 3.306 N/A THR 142.A N ARG 138.A O no hydrogen 3.068 N/A THR 142.A OG1 ARG 138.A O no hydrogen 3.203 N/A THR 142.A OG1 TYR 167.A OH no hydrogen 2.636 N/A GLU 143.A N GLU 139.A O no hydrogen 3.307 N/A ILE 144.A N GLU 140.A O no hydrogen 3.083 N/A GLU 145.A N ALA 141.A O no hydrogen 2.983 N/A GLN 146.A N THR 142.A O no hydrogen 2.907 N/A THR 147.A N GLU 143.A O no hydrogen 2.920 N/A THR 147.A OG1 GLU 143.A O no hydrogen 2.499 N/A VAL 148.A N ILE 144.A O no hydrogen 3.029 N/A GLN 149.A N GLU 145.A O no hydrogen 2.766 N/A LYS 150.A N GLN 146.A O no hydrogen 2.876 N/A ALA 151.A N THR 147.A O no hydrogen 3.295 N/A ALA 152.A N VAL 148.A O no hydrogen 2.887 N/A GLN 153.A N GLN 149.A O no hydrogen 2.677 N/A GLN 153.A NE2 GLN 149.A OE1 no hydrogen 2.696 N/A GLN 153.A NE2 LEU 159.A O no hydrogen 3.510 N/A ALA 154.A N LYS 150.A O no hydrogen 3.092 N/A PHE 155.A N ALA 152.A O no hydrogen 3.103 N/A ASN 156.A N ALA 152.A O no hydrogen 3.224 N/A GLY 158.A N ASN 156.A OD1 no hydrogen 2.451 N/A LEU 159.A N ASN 156.A O no hydrogen 3.061 N/A LEU 160.A N THR 182.A O no hydrogen 3.068 N/A VAL 162.A N LEU 180.A O no hydrogen 2.893 N/A ALA 163.A N GLU 145.A OE2 no hydrogen 3.110 N/A CYS 164.A N ASP 178.A O no hydrogen 2.692 N/A CYS 164.A SG VAL 162.A O no hydrogen 3.612 N/A GLY 165.A N PHE 250.A O no hydrogen 2.823 N/A TYR 167.A OH THR 142.A OG1 no hydrogen 2.636 N/A ARG 168.A N CYS 164.A O no hydrogen 3.181 N/A ARG 168.A NH1 THR 251.A OG1 no hydrogen 2.736 N/A ARG 168.A NH1 GLU 299.A OE1 no hydrogen 3.424 N/A ARG 168.A NH1 GLU 299.A OE2 no hydrogen 3.035 N/A ARG 168.A NH2 GLU 299.A OE1 no hydrogen 2.605 N/A ARG 169.A N GLY 165.A O no hydrogen 3.238 N/A ARG 169.A NE ASP 317.A OD1 no hydrogen 2.892 N/A ARG 169.A NH1 THR 251.A O no hydrogen 2.862 N/A ARG 169.A NH2 ASP 317.A OD1 no hydrogen 3.010 N/A GLY 170.A N TYR 167.A O no hydrogen 3.002 N/A LYS 171.A N SER 166.A O no hydrogen 3.114 N/A CYS 174.A N MET 136.A O no hydrogen 2.824 N/A CYS 174.A SG SER 166.A OG no hydrogen 3.650 N/A ASP 176.A O.B ASP 176.A OD1.B no hydrogen 3.257 N/A ASP 176.A OD1.B ASP 176.A O.B no hydrogen 3.257 N/A ASP 176.A OD1.B ASP 176.A OD2.B no hydrogen 2.194 N/A ASP 176.A OD1.B ASP 178.A OD1 no hydrogen 3.199 N/A ASP 176.A OD1.B ASP 178.A OD2 no hydrogen 2.965 N/A ASP 176.A OD2.B ASP 176.A OD1.B no hydrogen 2.194 N/A VAL 177.A N ARG 232.A O no hydrogen 3.227 N/A VAL 179.A N ASP 234.A O no hydrogen 2.823 N/A LEU 180.A N VAL 162.A O no hydrogen 2.745 N/A ILE 181.A N ILE 236.A O no hydrogen 2.791 N/A THR 182.A N LEU 160.A O no hydrogen 3.101 N/A THR 182.A OG1 VAL 238.A O no hydrogen 2.631 N/A GLY 186.A N HIS 183.A O no hydrogen 3.108 N/A ARG 187.A N ASP 185.A OD1 no hydrogen 2.520 N/A SER 188.A N ASP 185.A OD1 no hydrogen 2.664 N/A ARG 190.A N ARG 187.A O no hydrogen 3.445 N/A LEU 196.A N ILE 192.A O no hydrogen 3.051 N/A LEU 197.A N PHE 193.A O no hydrogen 2.788 N/A ASP 198.A N SER 194.A O no hydrogen 3.426 N/A SER 199.A N ARG 195.A O no hydrogen 2.990 N/A LEU 200.A N LEU 196.A O no hydrogen 2.925 N/A ARG 201.A N LEU 197.A O no hydrogen 2.761 N/A GLN 202.A N SER 199.A O no hydrogen 2.808 N/A GLU 203.A N LEU 200.A O no hydrogen 3.363 N/A GLY 204.A N ARG 201.A O no hydrogen 3.451 N/A LEU 206.A N LEU 200.A O no hydrogen 3.405 N/A THR 207.A N VAL 220.A O no hydrogen 2.800 N/A THR 207.A OG1 ASP 208.A OD1 no hydrogen 2.864 N/A THR 207.A OG1 VAL 220.A O no hydrogen 3.348 N/A ASP 208.A N VAL 220.A O no hydrogen 3.472 N/A LEU 210.A N LEU 218.A O no hydrogen 2.842 N/A VAL 211.A N LEU 218.A O no hydrogen 2.871 N/A GLY 213.A N LYS 216.A O no hydrogen 2.854 N/A TYR 217.A N ILE 235.A O no hydrogen 2.795 N/A TYR 217.A OH ASP 209.A OD1 no hydrogen 2.740 N/A LEU 218.A N VAL 211.A O no hydrogen 2.947 N/A GLY 219.A N LEU 233.A O no hydrogen 2.839 N/A VAL 220.A N ASP 208.A O no hydrogen 2.812 N/A CYS 221.A N ARG 231.A O no hydrogen 2.921 N/A CYS 221.A SG ARG 231.A O no hydrogen 3.850 N/A ARG 222.A N PHE 205.A O no hydrogen 2.944 N/A ARG 228.A NE PRO 224.A O no hydrogen 3.346 N/A ARG 228.A NH2 GLU 143.A OE1 no hydrogen 3.536 N/A ARG 228.A NH2 GLU 143.A OE2 no hydrogen 2.919 N/A HIS 230.A N ASP 131.A OD2 no hydrogen 2.731 N/A ARG 231.A N CYS 221.A O no hydrogen 2.832 N/A ARG 231.A NE GLU 140.A OE2 no hydrogen 2.994 N/A ARG 231.A NH2 GLU 140.A OE1 no hydrogen 3.024 N/A ARG 232.A NH1 GLY 219.A O no hydrogen 2.974 N/A ARG 232.A NH1 LEU 233.A O no hydrogen 3.206 N/A ARG 232.A NH1 ASP 234.A OD1 no hydrogen 2.762 N/A ARG 232.A NH2 ASP 234.A OD1 no hydrogen 2.806 N/A ARG 232.A NH2 ASP 234.A OD2 no hydrogen 3.490 N/A LEU 233.A N GLY 219.A O no hydrogen 3.009 N/A ASP 234.A N VAL 177.A O no hydrogen 2.913 N/A ILE 235.A N TYR 217.A O no hydrogen 2.770 N/A ILE 236.A N VAL 179.A O no hydrogen 2.837 N/A VAL 237.A N THR 215.A O no hydrogen 2.967 N/A VAL 238.A N ILE 181.A O no hydrogen 2.999 N/A GLU 242.A N PRO 239.A O no hydrogen 2.890 N/A PHE 243.A N TYR 240.A O no hydrogen 3.071 N/A CYS 245.A SG THR 296.A OG1 no hydrogen 3.618 N/A ALA 246.A N GLU 242.A O no hydrogen 2.926 N/A LEU 247.A N PHE 243.A O no hydrogen 2.667 N/A LEU 248.A N ALA 244.A O no hydrogen 2.927 N/A TYR 249.A N CYS 245.A O no hydrogen 2.887 N/A PHE 250.A N ALA 246.A O no hydrogen 2.933 N/A THR 251.A N LEU 247.A O no hydrogen 3.117 N/A THR 251.A OG1 LEU 247.A O no hydrogen 2.739 N/A GLY 252.A N LEU 248.A O no hydrogen 3.260 N/A SER 253.A N ARG 316.A O no hydrogen 2.979 N/A SER 253.A OG ARG 316.A O no hydrogen 3.296 N/A SER 253.A OG TRP 318.A OXT no hydrogen 3.146 N/A PHE 256.A N SER 253.A OG no hydrogen 3.250 N/A ASN 257.A N SER 253.A O no hydrogen 2.905 N/A ASN 257.A ND2 TYR 249.A O no hydrogen 2.936 N/A ARG 258.A N ALA 254.A O no hydrogen 2.899 N/A SER 259.A N HIS 255.A O.A no hydrogen 3.102 N/A SER 259.A N HIS 255.A O.B no hydrogen 2.953 N/A SER 259.A OG HIS 255.A O.A no hydrogen 2.988 N/A SER 259.A OG HIS 255.A O.B no hydrogen 3.090 N/A MET 260.A N PHE 256.A O no hydrogen 2.863 N/A ARG 261.A N ASN 257.A O no hydrogen 2.835 N/A ALA 262.A N ARG 258.A O no hydrogen 3.227 N/A LEU 263.A N SER 259.A O no hydrogen 3.101 N/A ALA 264.A N MET 260.A O no hydrogen 2.952 N/A LYS 265.A N ARG 261.A O no hydrogen 3.005 N/A LYS 265.A NZ HIS 284.A O no hydrogen 2.637 N/A THR 266.A N ALA 262.A O no hydrogen 3.142 N/A THR 266.A OG1 LEU 263.A O no hydrogen 2.656 N/A LYS 267.A N ALA 264.A O no hydrogen 3.009 N/A LYS 267.A NZ LEU 306.A O no hydrogen 3.026 N/A GLY 268.A N LYS 265.A O no hydrogen 3.175 N/A MET 269.A N ALA 264.A O no hydrogen 2.995 N/A SER 270.A N SER 277.A O no hydrogen 2.849 N/A SER 272.A N ALA 275.A O no hydrogen 3.020 N/A HIS 274.A N SER 272.A OG no hydrogen 2.884 N/A HIS 274.A ND1 GLU 242.A OE1 no hydrogen 2.894 N/A ALA 275.A N SER 272.A OG no hydrogen 3.347 N/A SER 277.A N SER 270.A O no hydrogen 2.895 N/A SER 277.A OG ARG 292.A O no hydrogen 3.513 N/A THR 278.A N ARG 292.A O no hydrogen 2.854 N/A VAL 280.A N GLY 268.A O no hydrogen 2.910 N/A VAL 281.A N GLY 289.A O no hydrogen 3.000 N/A ASN 283.A N GLY 285.A O no hydrogen 2.942 N/A LYS 287.A N VAL 281.A O no hydrogen 2.757 N/A ARG 292.A N THR 278.A O no hydrogen 3.221 N/A LEU 294.A N LEU 276.A O no hydrogen 2.746 N/A THR 296.A OG1 THR 296.A O no hydrogen 2.543 N/A THR 298.A N ASP 301.A OD2 no hydrogen 3.194 N/A THR 298.A OG1 ASP 301.A OD2 no hydrogen 2.694 N/A ASP 301.A N THR 298.A O no hydrogen 3.065 N/A ASP 301.A N THR 298.A OG1 no hydrogen 3.108 N/A PHE 303.A N GLU 299.A O no hydrogen 3.308 N/A ARG 304.A N LYS 300.A O no hydrogen 2.882 N/A ARG 304.A NH2 ASP 301.A OD1 no hydrogen 2.710 N/A LEU 305.A N ASP 301.A O no hydrogen 2.802 N/A LEU 306.A N VAL 302.A O no hydrogen 3.057 N/A GLY 307.A N ARG 304.A O no hydrogen 2.821 N/A LEU 308.A N PHE 303.A O no hydrogen 2.916 N/A TYR 310.A OH GLU 312.A OE2 no hydrogen 2.647 N/A GLU 315.A N GLU 312.A O no hydrogen 2.974 N/A ARG 316.A N PRO 313.A O no hydrogen 3.075 N/A ARG 316.A NE ARG 311.A O no hydrogen 2.877 N/A ARG 316.A NH1 GLU 299.A OE2 no hydrogen 2.799 N/A ARG 316.A NH2 GLU 299.A OE1 no hydrogen 3.485 N/A ARG 316.A NH2 GLU 299.A OE2 no hydrogen 3.399 N/A ARG 316.A NH2 ARG 311.A O no hydrogen 3.002 N/A TRP 318.A N SER 253.A OG no hydrogen 3.213 N/A TRP 318.A N ARG 316.A O no hydrogen 2.937 N/A TRP 318.A NE1 GLU 315.A O no hydrogen 3.114 N/A