Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7mhd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A NE GLU 200.A OE2 no hydrogen 3.118 N/A ARG 5.A NH1 GLU 200.A OE1 no hydrogen 3.212 N/A ARG 5.A NH1 GLU 200.A OE2 no hydrogen 3.429 N/A SER 6.A N ASN 3.A O no hydrogen 3.244 N/A SER 6.A OG ASN 3.A O no hydrogen 3.248 N/A LEU 7.A N LEU 4.A O no hydrogen 2.805 N/A LEU 8.A N ARG 5.A O no hydrogen 3.394 N/A GLY 13.A N ASN 10.A O no hydrogen 2.865 N/A THR 15.A OG1 TYR 73.A OH no hydrogen 2.532 N/A MET 17.A N GLY 55.A O no hydrogen 3.035 N/A ARG 18.A NE TYR 54.A OH no hydrogen 3.144 N/A ARG 18.A NH1 VAL 22.A O no hydrogen 3.005 N/A ARG 18.A NH2 ASN 20.A O no hydrogen 2.867 N/A ARG 18.A NH2 VAL 22.A O no hydrogen 2.768 N/A LEU 19.A N THR 53.A O no hydrogen 2.940 N/A ASN 20.A ND2 ALA 46.A O no hydrogen 3.066 N/A ASN 20.A ND2 ILE 51.A O no hydrogen 2.896 N/A VAL 22.A N ASN 20.A OD1 no hydrogen 3.325 N/A SER 24.A OG GLU 26.A OE2 no hydrogen 2.784 N/A GLU 26.A N SER 24.A OG no hydrogen 3.061 N/A ARG 27.A NH1 PRO 86.A O no hydrogen 2.915 N/A LEU 29.A N PRO 52.A O no hydrogen 2.981 N/A PHE 30.A N ARG 88.A O no hydrogen 3.033 N/A LEU 31.A N TYR 54.A O no hydrogen 2.996 N/A VAL 32.A N ALA 90.A O no hydrogen 2.774 N/A HIS 33.A N LEU 56.A O no hydrogen 3.356 N/A HIS 33.A ND1 PRO 34.A O no hydrogen 2.666 N/A HIS 33.A NE2 TYR 74.A OH no hydrogen 2.836 N/A GLU 36.A N GLU 36.A OE2 no hydrogen 2.903 N/A GLY 37.A N PRO 34.A O no hydrogen 2.970 N/A SER 38.A OG SER 6.A O no hydrogen 2.564 N/A PHE 42.A N THR 39.A O no hydrogen 2.886 N/A HIS 43.A N THR 40.A O no hydrogen 3.167 N/A SER 44.A OG GLU 266.A OE1 no hydrogen 2.736 N/A SER 44.A OG GLU 266.A OE2 no hydrogen 3.065 N/A ALA 46.A N PHE 42.A O no hydrogen 2.932 N/A SER 47.A N HIS 43.A O no hydrogen 3.061 N/A SER 47.A OG HIS 43.A O no hydrogen 3.409 N/A SER 47.A OG SER 44.A O no hydrogen 2.800 N/A ARG 48.A N LEU 45.A O no hydrogen 2.964 N/A ARG 48.A NH1 GLU 271.A OE2 no hydrogen 2.876 N/A ARG 48.A NH2 GLU 271.A OE1 no hydrogen 2.851 N/A ARG 48.A NH2 GLU 271.A OE2 no hydrogen 3.430 N/A LEU 49.A N ALA 46.A O no hydrogen 3.377 N/A SER 50.A N HIS 278.A NE2 no hydrogen 2.900 N/A SER 50.A OG HIS 278.A NE2 no hydrogen 3.259 N/A THR 53.A N ASN 20.A OD1 no hydrogen 3.207 N/A THR 53.A OG1 ILE 51.A O no hydrogen 3.040 N/A TYR 54.A N LEU 29.A O no hydrogen 2.957 N/A GLY 55.A N MET 17.A O no hydrogen 2.825 N/A LEU 56.A N LEU 31.A O no hydrogen 2.864 N/A GLN 57.A N THR 15.A O no hydrogen 2.915 N/A GLN 57.A NE2 PRO 14.A O no hydrogen 2.714 N/A CYS 58.A N GLY 37.A O no hydrogen 2.935 N/A ARG 60.A N PRO 11.A O no hydrogen 3.144 N/A ARG 60.A NE GLU 12.A OE2 no hydrogen 2.731 N/A ALA 61.A N THR 59.A OG1 no hydrogen 3.177 N/A ALA 62.A N THR 59.A O no hydrogen 3.078 N/A SER 66.A OG ASP 65.A OD2 no hydrogen 3.456 N/A SER 66.A OG SER 69.A OG no hydrogen 3.172 N/A SER 69.A N SER 66.A OG no hydrogen 2.815 N/A SER 69.A OG ASP 65.A OD1 no hydrogen 3.251 N/A SER 69.A OG ASP 65.A OD2 no hydrogen 2.741 N/A SER 69.A OG SER 66.A OG no hydrogen 3.172 N/A LEU 70.A N SER 66.A O no hydrogen 3.098 N/A ALA 71.A N ILE 67.A O no hydrogen 2.965 N/A ALA 72.A N HIS 68.A O no hydrogen 3.105 N/A TYR 73.A N SER 69.A O no hydrogen 3.023 N/A TYR 73.A OH THR 15.A OG1 no hydrogen 2.532 N/A TYR 74.A N LEU 70.A O no hydrogen 2.991 N/A TYR 74.A OH HIS 33.A NE2 no hydrogen 2.836 N/A ILE 75.A N ALA 71.A O no hydrogen 2.920 N/A ASP 76.A N ALA 72.A O no hydrogen 3.173 N/A CYS 77.A N TYR 73.A O no hydrogen 3.058 N/A CYS 77.A SG TYR 73.A O no hydrogen 3.341 N/A ILE 78.A N TYR 74.A O no hydrogen 2.983 N/A ARG 79.A N ILE 75.A O no hydrogen 3.188 N/A ARG 79.A NE PRO 83.A O no hydrogen 3.318 N/A ARG 79.A NE TYR 87.A OH no hydrogen 3.417 N/A ARG 79.A NH1 GLN 109.A OE1.A no hydrogen 3.204 N/A ARG 79.A NH1 GLN 109.A OE1.B no hydrogen 3.207 N/A ARG 79.A NH2 GLN 109.A OE1.A no hydrogen 3.519 N/A ARG 79.A NH2 GLN 109.A OE1.B no hydrogen 3.562 N/A GLN 80.A N CYS 77.A O no hydrogen 3.097 N/A GLN 80.A NE2 ASP 76.A O no hydrogen 3.054 N/A VAL 81.A N ILE 78.A O no hydrogen 2.854 N/A GLN 82.A N ILE 78.A O no hydrogen 2.901 N/A GLN 82.A NE2 GLU 84.A O no hydrogen 2.959 N/A GLN 82.A NE2 PRO 86.A O no hydrogen 2.856 N/A TYR 87.A OH GLN 82.A O no hydrogen 2.377 N/A ARG 88.A NH2 ARG 27.A O no hydrogen 2.708 N/A VAL 89.A N SER 118.A O no hydrogen 2.727 N/A ALA 90.A N PHE 30.A O no hydrogen 2.877 N/A GLY 91.A N PHE 120.A O no hydrogen 3.012 N/A TYR 92.A N VAL 32.A O no hydrogen 3.359 N/A TYR 92.A OH HIS 261.A O no hydrogen 2.483 N/A SER 93.A N PHE 122.A O no hydrogen 2.912 N/A SER 93.A OG HIS 261.A NE2 no hydrogen 2.775 N/A TYR 94.A OH LYS 211.A O no hydrogen 2.715 N/A GLY 95.A N TYR 92.A O no hydrogen 2.844 N/A ALA 96.A N SER 93.A O no hydrogen 2.767 N/A VAL 98.A N TYR 94.A O no hydrogen 3.465 N/A ALA 99.A N GLY 95.A O no hydrogen 2.829 N/A PHE 100.A N ALA 96.A O no hydrogen 3.180 N/A GLU 101.A N CYS 97.A O no hydrogen 3.261 N/A MET 102.A N VAL 98.A O no hydrogen 3.171 N/A CYS 103.A N ALA 99.A O no hydrogen 3.157 N/A CYS 103.A SG ALA 99.A O no hydrogen 3.657 N/A SER 104.A N PHE 100.A O no hydrogen 3.059 N/A SER 104.A OG PHE 100.A O no hydrogen 3.038 N/A GLN 105.A N GLU 101.A O no hydrogen 2.943 N/A LEU 106.A N MET 102.A O no hydrogen 2.966 N/A GLN 107.A N CYS 103.A O no hydrogen 2.802 N/A ALA 108.A N SER 104.A O no hydrogen 2.891 N/A GLN 109.A N.A GLN 105.A O no hydrogen 3.028 N/A GLN 109.A N.B GLN 105.A O no hydrogen 3.055 N/A GLN 110.A N GLN 107.A O no hydrogen 3.265 N/A SER 111.A N ALA 108.A O no hydrogen 3.103 N/A ASN 117.A N THR 115.A OG1 no hydrogen 3.223 N/A SER 118.A N TYR 87.A O no hydrogen 2.803 N/A PHE 120.A N VAL 89.A O no hydrogen 2.866 N/A LEU 121.A N MET 229.A O no hydrogen 2.818 N/A PHE 122.A N GLY 91.A O no hydrogen 2.750 N/A ASP 123.A N LEU 231.A O no hydrogen 2.701 N/A SER 125.A OG TYR 242.A O no hydrogen 2.876 N/A TYR 128.A N SER 125.A OG no hydrogen 2.875 N/A VAL 129.A N SER 125.A O no hydrogen 3.465 N/A ALA 131.A N THR 127.A O no hydrogen 2.799 N/A TYR 132.A N TYR 128.A O no hydrogen 3.455 N/A THR 133.A N VAL 129.A O no hydrogen 3.117 N/A THR 133.A OG1 LEU 130.A O no hydrogen 2.916 N/A GLN 134.A N LEU 130.A O no hydrogen 2.902 N/A SER 135.A N ALA 131.A O no hydrogen 3.035 N/A SER 135.A OG ALA 131.A O no hydrogen 3.516 N/A TYR 136.A N TYR 132.A O no hydrogen 3.232 N/A ARG 137.A N THR 133.A O no hydrogen 3.062 N/A ARG 137.A NE GLU 216.A OE1 no hydrogen 2.454 N/A ARG 137.A NH2 GLU 216.A OE2 no hydrogen 2.962 N/A ALA 138.A N GLN 134.A O no hydrogen 2.949 N/A ALA 138.A N SER 135.A O no hydrogen 3.246 N/A LYS 139.A NZ GLU 151.A OE2 no hydrogen 3.171 N/A LEU 140.A N ARG 137.A O no hydrogen 3.015 N/A THR 141.A OG1 GLU 147.A OE2 no hydrogen 2.963 N/A CYS 144.A N THR 141.A O no hydrogen 3.303 N/A CYS 144.A SG GLU 147.A OE2 no hydrogen 3.823 N/A GLU 147.A N CYS 144.A O no hydrogen 2.830 N/A ALA 148.A N CYS 144.A O no hydrogen 3.370 N/A GLU 149.A N GLU 145.A O no hydrogen 2.881 N/A THR 150.A N ALA 146.A O no hydrogen 2.997 N/A THR 150.A OG1 ALA 146.A O no hydrogen 2.882 N/A GLU 151.A N GLU 147.A O no hydrogen 2.933 N/A ALA 152.A N ALA 148.A O no hydrogen 3.006 N/A ILE 153.A N GLU 149.A O no hydrogen 2.965 N/A CYS 154.A N THR 150.A O no hydrogen 2.901 N/A CYS 154.A SG GLN 158.A OE1 no hydrogen 3.438 N/A CYS 154.A SG HIS 165.A ND1 no hydrogen 3.284 N/A CYS 154.A SG HIS 165.A O no hydrogen 3.615 N/A PHE 155.A N GLU 151.A O no hydrogen 3.092 N/A PHE 156.A N ALA 152.A O no hydrogen 3.081 N/A VAL 157.A N ILE 153.A O no hydrogen 2.895 N/A GLN 158.A N CYS 154.A O no hydrogen 2.961 N/A GLN 159.A N.A PHE 156.A O no hydrogen 3.063 N/A GLN 159.A N.B PHE 155.A O no hydrogen 3.264 N/A GLN 159.A N.B PHE 156.A O no hydrogen 3.057 N/A GLN 159.A NE2.A PHE 155.A O no hydrogen 2.549 N/A PHE 160.A N VAL 157.A O no hydrogen 3.088 N/A THR 161.A N VAL 157.A O no hydrogen 3.092 N/A THR 161.A OG1 VAL 157.A O no hydrogen 3.114 N/A MET 163.A N THR 161.A OG1 no hydrogen 3.408 N/A HIS 165.A ND1 GLN 158.A OE1 no hydrogen 3.221 N/A ASN 166.A N GLU 164.A OE2 no hydrogen 3.006 N/A VAL 168.A N HIS 165.A O no hydrogen 3.189 N/A LEU 169.A N HIS 165.A O no hydrogen 2.927 N/A GLU 170.A N ASN 166.A O no hydrogen 2.895 N/A ALA 171.A N VAL 168.A O no hydrogen 3.192 N/A LEU 172.A N VAL 168.A O no hydrogen 3.236 N/A LEU 173.A N LEU 169.A O no hydrogen 2.939 N/A LEU 175.A N LEU 172.A O no hydrogen 3.261 N/A LYS 176.A N GLU 180.A OE1.A no hydrogen 2.967 N/A LYS 176.A NZ GLU 180.A OE2.A no hydrogen 2.788 N/A ARG 181.A N.A GLY 177.A O no hydrogen 3.238 N/A ARG 181.A N.B GLY 177.A O no hydrogen 3.179 N/A ARG 181.A NE.A GLU 149.A OE2 no hydrogen 2.715 N/A ARG 181.A NE.B THR 150.A OG1 no hydrogen 2.787 N/A ARG 181.A NE.B LEU 172.A O no hydrogen 2.744 N/A ARG 181.A NH1.A GLU 149.A OE2 no hydrogen 2.755 N/A ARG 181.A NH1.B LEU 173.A O no hydrogen 2.604 N/A ARG 181.A NH2.A LEU 172.A O no hydrogen 3.088 N/A ARG 181.A NH2.A LEU 175.A O no hydrogen 2.936 N/A VAL 182.A N LEU 178.A O no hydrogen 2.759 N/A ALA 183.A N GLU 179.A O no hydrogen 2.965 N/A ALA 184.A N GLU 180.A O.A no hydrogen 2.890 N/A ALA 184.A N GLU 180.A O.B no hydrogen 3.103 N/A ALA 185.A N ARG 181.A O.A no hydrogen 2.965 N/A ALA 185.A N ARG 181.A O.B no hydrogen 2.956 N/A VAL 186.A N VAL 182.A O no hydrogen 2.981 N/A ASP 187.A N ALA 183.A O no hydrogen 3.195 N/A LEU 188.A N ALA 184.A O no hydrogen 3.144 N/A ILE 189.A N ALA 185.A O no hydrogen 3.062 N/A ILE 190.A N VAL 186.A O no hydrogen 2.811 N/A LYS 191.A N ASP 187.A O no hydrogen 3.061 N/A SER 192.A N LEU 188.A O no hydrogen 3.378 N/A SER 192.A OG LEU 188.A O no hydrogen 3.259 N/A HIS 193.A N ILE 189.A O no hydrogen 2.766 N/A HIS 193.A N ILE 190.A O no hydrogen 3.193 N/A HIS 193.A NE2 PHE 160.A O no hydrogen 2.661 N/A LEU 196.A N HIS 193.A O no hydrogen 3.215 N/A ARG 198.A NH2 ASP 187.A OD1 no hydrogen 2.879 N/A GLU 200.A N ASP 197.A OD2 no hydrogen 2.726 N/A LEU 201.A N ASP 197.A O no hydrogen 3.099 N/A SER 202.A N ARG 198.A O no hydrogen 2.894 N/A SER 202.A OG ARG 198.A O no hydrogen 2.892 N/A PHE 203.A N GLN 199.A O no hydrogen 2.939 N/A ALA 204.A N GLU 200.A O no hydrogen 2.997 N/A ALA 205.A N LEU 201.A O no hydrogen 2.791 N/A ARG 206.A N SER 202.A O no hydrogen 3.100 N/A ARG 206.A NE GLU 179.A OE1 no hydrogen 2.698 N/A ARG 206.A NH1 GLU 179.A OE2 no hydrogen 3.133 N/A SER 207.A N PHE 203.A O no hydrogen 2.938 N/A SER 207.A OG PHE 203.A O no hydrogen 3.042 N/A SER 207.A OG ALA 204.A O no hydrogen 3.170 N/A PHE 208.A N ALA 204.A O no hydrogen 2.965 N/A TYR 209.A N ARG 206.A O no hydrogen 3.172 N/A TYR 210.A N ARG 206.A O no hydrogen 3.351 N/A LYS 211.A N SER 207.A O no hydrogen 2.733 N/A LYS 211.A NZ ILE 35.A O no hydrogen 2.731 N/A LEU 212.A N PHE 208.A O no hydrogen 3.110 N/A ARG 213.A N TYR 209.A O no hydrogen 3.087 N/A ARG 213.A NE GLN 217.A OE1 no hydrogen 2.820 N/A ARG 213.A NH1 TYR 209.A OH no hydrogen 3.459 N/A ARG 213.A NH2 GLN 217.A OE1 no hydrogen 2.915 N/A ALA 214.A N TYR 210.A O no hydrogen 3.023 N/A ALA 215.A N LYS 211.A O no hydrogen 3.169 N/A GLU 216.A N LEU 212.A O no hydrogen 3.060 N/A GLN 217.A N ARG 213.A O no hydrogen 3.298 N/A TYR 218.A N ALA 215.A O no hydrogen 3.185 N/A TYR 218.A OH GLU 101.A OE2 no hydrogen 2.357 N/A LYS 223.A NZ GLN 246.A O no hydrogen 2.983 N/A TYR 224.A N VAL 247.A O no hydrogen 2.676 N/A HIS 225.A N GLN 107.A OE1 no hydrogen 2.579 N/A HIS 225.A ND1 ASP 249.A OD1 no hydrogen 2.683 N/A HIS 225.A ND1 ASP 249.A OD2 no hydrogen 3.133 N/A VAL 228.A N LYS 251.A O no hydrogen 2.966 N/A MET 229.A N LEU 119.A O no hydrogen 3.127 N/A LEU 230.A N SER 253.A O no hydrogen 2.774 N/A LEU 231.A N LEU 121.A O no hydrogen 2.869 N/A ARG 232.A N HIS 255.A O no hydrogen 3.203 N/A ARG 232.A NE ALA 240.A O no hydrogen 2.681 N/A ALA 233.A N ASP 123.A OD1 no hydrogen 3.068 N/A LYS 234.A N ILE 257.A O no hydrogen 2.706 N/A THR 235.A N GLY 259.A O no hydrogen 3.079 N/A THR 235.A OG1 THR 235.A O no hydrogen 2.548 N/A THR 235.A OG1 GLY 259.A O no hydrogen 3.061 N/A GLY 239.A N ASP 237.A OD1 no hydrogen 3.107 N/A TYR 242.A OH ASP 123.A OD1 no hydrogen 2.599 N/A ASN 243.A N ASP 241.A OD1 no hydrogen 2.914 N/A ASN 243.A ND2 LEU 238.A O no hydrogen 2.323 N/A LEU 244.A N ASP 241.A O no hydrogen 3.009 N/A SER 245.A N ASP 241.A OD2 no hydrogen 2.707 N/A SER 245.A OG ASP 241.A OD2 no hydrogen 3.250 N/A GLN 246.A N ASN 243.A O no hydrogen 3.197 N/A GLN 246.A NE2 ASN 243.A O no hydrogen 3.654 N/A VAL 247.A N LEU 244.A O no hydrogen 2.839 N/A CYS 248.A N.A LEU 244.A O no hydrogen 2.746 N/A CYS 248.A N.B LEU 244.A O no hydrogen 2.788 N/A CYS 248.A SG.A LEU 244.A O no hydrogen 3.314 N/A CYS 248.A SG.B TYR 224.A O no hydrogen 3.174 N/A CYS 248.A SG.B GLY 226.A O no hydrogen 3.181 N/A ASP 249.A N TYR 224.A O no hydrogen 2.932 N/A LYS 251.A N ASN 227.A OD1.B no hydrogen 2.642 N/A SER 253.A N VAL 228.A O no hydrogen 3.060 N/A HIS 255.A N LEU 230.A O no hydrogen 2.845 N/A ILE 257.A N ARG 232.A O no hydrogen 3.001 N/A ASP 260.A N THR 263.A OG1 no hydrogen 2.939 N/A HIS 261.A ND1 ASP 123.A OD2 no hydrogen 2.928 N/A HIS 261.A NE2 SER 93.A OG no hydrogen 2.775 N/A ARG 262.A N ASP 260.A OD1 no hydrogen 2.853 N/A THR 263.A N ASP 260.A O no hydrogen 3.081 N/A THR 263.A N ASP 260.A OD1 no hydrogen 2.900 N/A THR 263.A OG1 ASP 260.A OD1 no hydrogen 3.202 N/A GLU 266.A N THR 263.A O no hydrogen 3.137 N/A LEU 270.A N GLU 266.A O no hydrogen 2.957 N/A GLU 271.A N GLY 267.A O no hydrogen 3.276 N/A SER 272.A N SER 268.A O no hydrogen 3.385 N/A SER 272.A OG SER 268.A O no hydrogen 3.469 N/A ILE 273.A N GLY 269.A O no hydrogen 3.068 N/A ILE 274.A N LEU 270.A O no hydrogen 2.912 N/A SER 275.A N GLU 271.A O no hydrogen 3.089 N/A SER 275.A OG GLU 271.A O no hydrogen 3.195 N/A ILE 276.A N SER 272.A O no hydrogen 2.825 N/A ILE 277.A N ILE 273.A O no hydrogen 2.813 N/A HIS 278.A N ILE 274.A O no hydrogen 2.913 N/A SER 279.A N SER 275.A O no hydrogen 3.008 N/A SER 279.A OG SER 275.A O no hydrogen 2.638 N/A SER 279.A OG ILE 276.A O no hydrogen 3.364 N/A SER 280.A N ILE 276.A O no hydrogen 2.811 N/A LEU 281.A N ILE 277.A O no hydrogen 3.062 N/A ALA 282.A N SER 279.A O no hydrogen 3.261 N/A