Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7mku_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N ASN 3.A OD1 no hydrogen 2.488 N/A LEU 7.A N ASN 3.A O no hydrogen 3.377 N/A LEU 8.A N SER 4.A O no hydrogen 2.924 N/A ALA 9.A N ASP 5.A O no hydrogen 2.939 N/A HIS 10.A N LEU 7.A O no hydrogen 3.133 N/A THR 15.A N ASN 108.A O no hydrogen 3.062 N/A ARG 16.A NH2 GLU 133.A OE2 no hydrogen 3.055 N/A TYR 17.A N LEU 106.A O no hydrogen 3.134 N/A THR 18.A OG1 SER 105.A OG no hydrogen 3.263 N/A TYR 19.A N ALA 104.A O no hydrogen 3.069 N/A TYR 19.A OH PRO 101.A O no hydrogen 2.861 N/A ASN 20.A N ASP 23.A OD1 no hydrogen 3.148 N/A GLU 21.A N GLU 21.A OE1 no hydrogen 2.473 N/A ASP 23.A N ASN 20.A OD1 no hydrogen 3.026 N/A VAL 24.A N ASN 20.A O no hydrogen 3.094 N/A ALA 25.A N GLU 21.A O no hydrogen 3.023 N/A ILE 26.A N ARG 22.A O no hydrogen 2.927 N/A TYR 27.A N ASP 23.A O no hydrogen 2.983 N/A TYR 27.A OH THR 61.A OG1 no hydrogen 2.712 N/A ALA 28.A N VAL 24.A O no hydrogen 2.839 N/A LEU 29.A N ALA 25.A O no hydrogen 2.871 N/A GLY 30.A N ILE 26.A O no hydrogen 2.888 N/A ILE 31.A N TYR 27.A O no hydrogen 3.038 N/A ILE 31.A N ALA 28.A O no hydrogen 3.292 N/A GLY 32.A N LEU 29.A O no hydrogen 3.001 N/A ALA 33.A N ALA 28.A O no hydrogen 2.912 N/A CYS 34.A N GLU 43.A OE1 no hydrogen 2.694 N/A GLY 35.A N GLY 32.A O no hydrogen 2.860 N/A ASP 40.A N ASP 37.A O no hydrogen 3.426 N/A ASP 42.A N ASP 40.A OD1 no hydrogen 3.029 N/A GLU 43.A N ASP 40.A O no hydrogen 3.249 N/A LEU 44.A N ASP 40.A O no hydrogen 2.805 N/A LYS 45.A NZ ASP 42.A O no hydrogen 3.020 N/A PHE 46.A N GLU 43.A O no hydrogen 2.943 N/A VAL 47.A N LEU 44.A O no hydrogen 2.958 N/A TYR 48.A N LEU 44.A O no hydrogen 2.927 N/A ASN 51.A N HIS 49.A ND1 no hydrogen 2.787 N/A GLY 52.A N HIS 49.A O no hydrogen 3.183 N/A GLN 53.A NE2 VAL 47.A O no hydrogen 2.894 N/A LEU 55.A N GLY 52.A O no hydrogen 3.144 N/A ILE 56.A N GLN 53.A O no hydrogen 3.152 N/A GLN 57.A N LYS 45.A O no hydrogen 3.043 N/A THR 61.A OG1 TYR 27.A OH no hydrogen 2.712 N/A PHE 62.A N LEU 59.A O no hydrogen 2.901 N/A ALA 63.A N PRO 60.A O no hydrogen 3.007 N/A SER 64.A N THR 61.A O no hydrogen 2.972 N/A SER 64.A OG THR 61.A O no hydrogen 2.748 N/A LEU 65.A N PHE 62.A O no hydrogen 2.919 N/A PHE 66.A N ALA 63.A O no hydrogen 3.121 N/A THR 67.A N SER 64.A O no hydrogen 3.463 N/A THR 67.A OG1 SER 64.A O no hydrogen 2.906 N/A LEU 68.A N LEU 65.A O no hydrogen 3.274 N/A SER 70.A OG THR 67.A O no hydrogen 2.843 N/A GLU 73.A N GLY 69.A O no hydrogen 3.209 N/A PHE 80.A N LEU 77.A O no hydrogen 3.133 N/A TYR 82.A OH LEU 71.A O no hydrogen 2.626 N/A TYR 82.A OH GLY 74.A O no hydrogen 2.864 N/A SER 85.A N ASP 83.A OD1 no hydrogen 3.151 N/A SER 85.A OG ASP 83.A OD1 no hydrogen 2.537 N/A LEU 86.A N ASP 83.A O no hydrogen 3.083 N/A LEU 87.A N PRO 84.A O no hydrogen 3.409 N/A LEU 88.A N PHE 146.A O no hydrogen 2.906 N/A HIS 89.A NE2 GLN 92.A OE1 no hydrogen 3.042 N/A GLY 90.A N THR 144.A O no hydrogen 2.839 N/A GLN 91.A N THR 144.A O no hydrogen 3.209 N/A GLN 92.A N GLY 252.A O no hydrogen 2.919 N/A GLN 92.A NE2 ASN 141.A OD1 no hydrogen 2.746 N/A TYR 93.A N ARG 142.A O no hydrogen 2.987 N/A TYR 93.A OH GLU 95.A OE2 no hydrogen 2.694 N/A ILE 94.A N ILE 250.A O no hydrogen 2.765 N/A ILE 96.A N LYS 248.A O no hydrogen 2.919 N/A TYR 97.A N LEU 139.A O no hydrogen 2.992 N/A TYR 97.A OH GLU 95.A OE1 no hydrogen 2.837 N/A ARG 98.A NH2 GLU 132.A OE2 no hydrogen 2.953 N/A SER 102.A OG ASP 54.A O no hydrogen 2.621 N/A ALA 104.A N TYR 19.A O no hydrogen 3.104 N/A SER 105.A OG THR 18.A OG1 no hydrogen 3.263 N/A SER 105.A OG GLU 133.A OE1 no hydrogen 3.238 N/A LEU 106.A N TYR 17.A O no hydrogen 2.767 N/A ILE 107.A N TYR 131.A O no hydrogen 2.800 N/A ASN 108.A N THR 15.A O no hydrogen 2.798 N/A ASN 108.A ND2 THR 15.A OG1 no hydrogen 3.382 N/A LYS 109.A N ARG 129.A O no hydrogen 2.790 N/A SER 111.A N GLU 127.A O no hydrogen 2.807 N/A ALA 113.A N GLU 125.A O no hydrogen 2.931 N/A GLY 114.A N GLU 125.A O no hydrogen 3.263 N/A LEU 115.A N TYR 162.A O no hydrogen 2.916 N/A GLN 116.A N ILE 123.A O no hydrogen 2.690 N/A ASP 117.A N PHE 160.A O no hydrogen 2.918 N/A LYS 118.A N ALA 121.A O no hydrogen 2.832 N/A GLY 119.A N ASP 117.A OD1 no hydrogen 3.311 N/A ALA 122.A N LEU 147.A O no hydrogen 3.092 N/A ILE 123.A N GLN 116.A O no hydrogen 2.757 N/A LEU 124.A N VAL 145.A O no hydrogen 3.095 N/A GLU 125.A N GLY 114.A O no hydrogen 2.832 N/A LEU 126.A N THR 143.A O no hydrogen 2.901 N/A GLU 127.A N SER 111.A O no hydrogen 2.807 N/A THR 128.A N ASN 141.A O no hydrogen 2.942 N/A ARG 129.A N LYS 109.A O no hydrogen 2.721 N/A SER 130.A N CYS 140.A O no hydrogen 3.096 N/A SER 130.A OG ASN 108.A OD1 no hydrogen 2.625 N/A TYR 131.A N ILE 107.A O no hydrogen 2.774 N/A GLU 132.A N GLU 137.A O no hydrogen 2.965 N/A GLU 133.A N SER 105.A O no hydrogen 2.835 N/A SER 135.A OG GLU 132.A OE2 no hydrogen 3.085 N/A GLY 136.A N GLU 132.A O no hydrogen 2.746 N/A GLU 137.A N SER 135.A OG no hydrogen 3.277 N/A LEU 139.A N SER 130.A O no hydrogen 2.803 N/A ASN 141.A ND2 ALA 63.A O no hydrogen 2.950 N/A ARG 142.A N TYR 93.A O no hydrogen 2.767 N/A ARG 142.A NH1 GLU 127.A OE1 no hydrogen 2.452 N/A ARG 142.A NH1 GLN 169.A OE1 no hydrogen 3.331 N/A ARG 142.A NH2 GLN 169.A OE1 no hydrogen 2.664 N/A THR 143.A N LEU 126.A O no hydrogen 2.836 N/A THR 143.A OG1 GLN 92.A OE1 no hydrogen 3.254 N/A THR 144.A N GLN 91.A O no hydrogen 3.017 N/A THR 144.A OG1 GLU 125.A OE1 no hydrogen 2.800 N/A VAL 145.A N LEU 124.A O no hydrogen 2.969 N/A PHE 146.A N LEU 88.A O no hydrogen 2.756 N/A LEU 147.A N ALA 122.A O no hydrogen 2.843 N/A ARG 148.A N LEU 86.A O no hydrogen 3.267 N/A ARG 148.A NE LEU 86.A O no hydrogen 3.166 N/A ALA 150.A N LEU 147.A O no hydrogen 3.316 N/A GLY 151.A N LYS 120.A O no hydrogen 2.868 N/A GLY 152.A N ASP 117.A OD1 no hydrogen 2.793 N/A SER 154.A N ASP 117.A OD2 no hydrogen 3.181 N/A SER 154.A OG ASP 117.A OD2 no hydrogen 2.705 N/A SER 154.A OG ASN 155.A O no hydrogen 3.553 N/A GLN 158.A N ASN 155.A O no hydrogen 3.128 N/A PHE 160.A N SER 154.A OG no hydrogen 3.221 N/A TYR 162.A N LEU 115.A O no hydrogen 2.880 N/A ASN 164.A N ALA 113.A O no hydrogen 2.779 N/A TYR 165.A OH GLU 125.A OE1 no hydrogen 2.840 N/A TYR 165.A OH GLU 125.A OE2 no hydrogen 2.781 N/A GLN 169.A N PRO 166.A O no hydrogen 3.052 N/A GLY 170.A N TYR 291.A OH no hydrogen 2.800 N/A LEU 171.A N ASN 168.A O no hydrogen 3.151 N/A ARG 178.A NH2 GLU 270.A OE1 no hydrogen 3.264 N/A CYS 184.A N THR 266.A O no hydrogen 3.058 N/A GLU 186.A N LEU 264.A O no hydrogen 2.961 N/A THR 188.A N GLU 262.A O no hydrogen 2.984 N/A THR 188.A OG1 GLU 262.A O no hydrogen 2.767 N/A GLN 189.A N GLN 192.A OE1 no hydrogen 2.716 N/A GLN 192.A N GLN 189.A O no hydrogen 2.900 N/A GLN 192.A NE2 LEU 29.A O no hydrogen 3.540 N/A GLN 192.A NE2 GLY 30.A O no hydrogen 2.899 N/A LEU 195.A N SER 191.A O no hydrogen 3.042 N/A TYR 196.A N GLN 192.A O no hydrogen 2.828 N/A ARG 197.A N ALA 193.A O no hydrogen 2.953 N/A ARG 197.A NH2 TYR 202.A O no hydrogen 2.976 N/A LEU 198.A N LEU 195.A O no hydrogen 3.073 N/A SER 199.A N TYR 196.A O no hydrogen 3.012 N/A GLY 200.A N ARG 197.A O no hydrogen 2.988 N/A ASN 203.A N ASP 201.A OD1 no hydrogen 3.160 N/A LEU 205.A N ASN 203.A OD1 no hydrogen 3.109 N/A HIS 206.A N ASN 203.A O no hydrogen 3.053 N/A HIS 206.A ND1 ILE 221.A O no hydrogen 2.756 N/A SER 207.A N PRO 204.A O no hydrogen 3.150 N/A ASP 208.A N PRO 204.A O no hydrogen 2.921 N/A PHE 211.A N ASP 208.A OD1 no hydrogen 2.959 N/A ALA 212.A N ASP 208.A O no hydrogen 2.941 N/A LYS 213.A N PRO 209.A O no hydrogen 3.069 N/A LEU 214.A N GLU 210.A O no hydrogen 3.167 N/A ALA 215.A N PHE 211.A O no hydrogen 3.287 N/A ALA 215.A N ALA 212.A O no hydrogen 3.146 N/A GLY 216.A N LYS 213.A O no hydrogen 2.862 N/A PHE 217.A N ALA 212.A O no hydrogen 2.980 N/A ILE 221.A N LEU 205.A O no hydrogen 3.292 N/A LEU 222.A N VAL 258.A O no hydrogen 2.867 N/A HIS 223.A NE2 ASP 201.A O no hydrogen 3.163 N/A CYS 226.A N HIS 223.A O no hydrogen 2.964 N/A CYS 226.A SG GLY 30.A O no hydrogen 3.222 N/A THR 227.A N HIS 223.A O no hydrogen 3.152 N/A THR 227.A OG1 HIS 223.A O no hydrogen 3.377 N/A LEU 228.A N GLY 224.A O no hydrogen 2.824 N/A GLY 229.A N LEU 225.A O no hydrogen 2.995 N/A PHE 230.A N CYS 226.A O no hydrogen 3.032 N/A ALA 231.A N THR 227.A O no hydrogen 2.966 N/A ILE 232.A N LEU 228.A O no hydrogen 2.915 N/A LYS 233.A N GLY 229.A O no hydrogen 2.894 N/A LYS 233.A NZ GLY 32.A O no hydrogen 2.933 N/A LYS 233.A NZ GLU 43.A OE2 no hydrogen 3.302 N/A LYS 233.A NZ GLU 186.A OE1 no hydrogen 3.380 N/A LYS 233.A NZ GLU 186.A OE2 no hydrogen 2.481 N/A ALA 234.A N PHE 230.A O no hydrogen 3.003 N/A ILE 235.A N ALA 231.A O no hydrogen 3.009 N/A ILE 236.A N ILE 232.A O no hydrogen 2.852 N/A LYS 237.A N LYS 233.A O no hydrogen 2.945 N/A LYS 237.A NZ GLU 43.A OE2 no hydrogen 2.860 N/A CYS 238.A N ALA 234.A O no hydrogen 2.854 N/A CYS 238.A SG ALA 234.A O no hydrogen 3.234 N/A VAL 239.A N ILE 235.A O no hydrogen 2.801 N/A CYS 240.A N ILE 235.A O no hydrogen 3.185 N/A GLY 242.A N ILE 236.A O no hydrogen 2.869 N/A ASP 243.A N CYS 240.A O no hydrogen 3.016 N/A THR 245.A N ASP 243.A OD1 no hydrogen 2.801 N/A THR 245.A OG1 ASP 243.A OD1 no hydrogen 2.753 N/A THR 245.A OG1 ASP 243.A OD2 no hydrogen 3.181 N/A ALA 246.A N ASP 243.A O no hydrogen 3.101 N/A VAL 247.A N PRO 244.A O no hydrogen 3.304 N/A LYS 248.A N ASP 293.A O no hydrogen 2.882 N/A THR 249.A N ASP 293.A O no hydrogen 3.286 N/A ILE 250.A N ILE 94.A O no hydrogen 2.838 N/A SER 251.A N TYR 291.A O no hydrogen 2.876 N/A GLY 252.A N GLN 92.A O no hydrogen 2.967 N/A ARG 253.A N ALA 289.A O no hydrogen 2.675 N/A ARG 253.A NE.A GLY 170.A O no hydrogen 3.155 N/A ARG 253.A NH2.A GLY 170.A O no hydrogen 2.949 N/A PHE 254.A N GLY 90.A O no hydrogen 2.886 N/A LEU 255.A N VAL 287.A O no hydrogen 2.969 N/A PHE 259.A N GLU 262.A OE1 no hydrogen 2.979 N/A GLY 261.A N THR 188.A OG1 no hydrogen 2.880 N/A GLU 262.A N PHE 259.A O no hydrogen 2.970 N/A THR 263.A N GLU 282.A OE1 no hydrogen 2.873 N/A THR 263.A N GLU 282.A OE2 no hydrogen 3.278 N/A THR 263.A OG1 GLU 282.A OE2 no hydrogen 3.056 N/A LEU 264.A N GLU 186.A O no hydrogen 2.929 N/A ILE 265.A N LYS 279.A O no hydrogen 2.799 N/A THR 266.A N CYS 184.A O no hydrogen 2.839 N/A THR 266.A OG1 THR 278.A OG1 no hydrogen 3.082 N/A GLU 267.A N GLN 277.A O no hydrogen 2.837 N/A TRP 268.A NE1 ARG 178.A O no hydrogen 3.175 N/A GLU 270.A N ARG 273.A O no hydrogen 2.857 N/A ARG 273.A N GLU 270.A O no hydrogen 3.026 N/A ARG 273.A NE ASP 293.A OD1 no hydrogen 2.941 N/A ARG 273.A NH2 ASP 293.A OD1 no hydrogen 3.478 N/A ARG 273.A NH2 ASP 293.A OD2 no hydrogen 3.096 N/A VAL 274.A N VAL 292.A O no hydrogen 2.784 N/A ILE 275.A N TRP 268.A O no hydrogen 2.856 N/A TYR 276.A N GLY 290.A O no hydrogen 2.997 N/A TYR 276.A OH SER 251.A O no hydrogen 2.855 N/A GLN 277.A N GLU 267.A O no hydrogen 3.091 N/A THR 278.A N LEU 288.A O no hydrogen 2.897 N/A THR 278.A OG1 THR 266.A OG1 no hydrogen 3.082 N/A LYS 279.A N ILE 265.A O no hydrogen 2.726 N/A LYS 279.A NZ GLU 267.A OE1 no hydrogen 3.333 N/A VAL 280.A N LYS 285.A O no hydrogen 2.894 N/A LYS 281.A N THR 263.A O no hydrogen 2.821 N/A LYS 281.A NZ GLU 185.A OE1 no hydrogen 3.021 N/A LYS 281.A NZ GLU 185.A OE2 no hydrogen 2.990 N/A GLU 282.A N GLU 282.A OE1 no hydrogen 2.693 N/A ARG 283.A NH1 THR 257.A O no hydrogen 3.495 N/A ARG 283.A NH1 GLU 262.A OE2 no hydrogen 2.891 N/A ARG 283.A NH2 THR 257.A O no hydrogen 2.796 N/A ASN 284.A N LYS 281.A O no hydrogen 3.391 N/A VAL 287.A N THR 278.A O no hydrogen 2.871 N/A ALA 289.A N ARG 253.A O no hydrogen 3.130 N/A GLY 290.A N TYR 276.A O no hydrogen 3.174 N/A TYR 291.A N SER 251.A O no hydrogen 3.084 N/A VAL 292.A N VAL 274.A O no hydrogen 2.847 N/A ASP 293.A N THR 249.A O no hydrogen 3.245 N/A ILE 294.A N LEU 272.A O no hydrogen 2.887 N/A ARG 295.A N ALA 246.A O no hydrogen 2.755 N/A ARG 295.A NH1 THR 245.A OG1 no hydrogen 2.999 N/A ARG 295.A NH2 ASP 243.A OD2 no hydrogen 2.815 N/A SER 300.A N LEU 297.A O no hydrogen 3.341 N/A