Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7mkz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N GLU 1.A O no hydrogen 2.975 N/A PHE 6.A N MET 2.A O no hydrogen 2.824 N/A GLU 7.A N GLU 3.A O no hydrogen 2.991 N/A GLN 8.A N LYS 4.A O no hydrogen 2.968 N/A ILE 9.A N GLU 5.A O no hydrogen 2.972 N/A ASP 10.A N PHE 6.A O no hydrogen 2.866 N/A LYS 11.A N GLU 7.A O no hydrogen 2.734 N/A SER 12.A N GLN 8.A O no hydrogen 2.834 N/A SER 12.A OG GLN 8.A O no hydrogen 3.085 N/A SER 12.A OG ILE 9.A O no hydrogen 3.442 N/A SER 12.A OG SER 14.A OG.B no hydrogen 2.813 N/A GLY 13.A N ASP 10.A O no hydrogen 2.994 N/A SER 14.A N.A ILE 9.A O no hydrogen 3.114 N/A SER 14.A N.B ILE 9.A O no hydrogen 3.138 N/A SER 14.A OG.A SER 14.A O.A no hydrogen 2.504 N/A SER 14.A OG.B SER 12.A OG no hydrogen 2.813 N/A TRP 15.A NE1 ASP 10.A OD1 no hydrogen 2.816 N/A ILE 18.A N SER 14.A O.A no hydrogen 2.997 N/A ILE 18.A N SER 14.A O.B no hydrogen 2.889 N/A TYR 19.A N TRP 15.A O no hydrogen 2.787 N/A TYR 19.A OH ILE 260.A O no hydrogen 2.611 N/A GLN 20.A N ALA 16.A O no hydrogen 2.888 N/A ASP 21.A N ALA 17.A O no hydrogen 3.048 N/A ILE 22.A N ILE 18.A O no hydrogen 3.135 N/A ARG 23.A N TYR 19.A O no hydrogen 3.084 N/A ARG 23.A NH1 GLN 20.A OE1 no hydrogen 2.774 N/A HIS 24.A N GLN 20.A O no hydrogen 3.021 N/A GLU 25.A N ASP 21.A O no hydrogen 2.919 N/A CYS 31.A SG PHE 29.A O no hydrogen 3.915 N/A CYS 31.A SG SER 49.A O no hydrogen 3.996 N/A CYS 31.A SG PRO 50.A O no hydrogen 3.250 N/A ARG 32.A N ASP 52.A OD2 no hydrogen 2.795 N/A VAL 33.A N ASP 52.A OD1 no hydrogen 2.951 N/A LYS 35.A N CYS 31.A O no hydrogen 3.247 N/A LYS 35.A N ARG 32.A O no hydrogen 3.225 N/A LYS 35.A NZ ARG 46.A O no hydrogen 3.239 N/A LEU 36.A N VAL 33.A O no hydrogen 3.060 N/A ASN 39.A N LEU 36.A O no hydrogen 2.904 N/A ASN 39.A ND2 VAL 33.A O no hydrogen 2.882 N/A LYS 40.A N PRO 37.A O no hydrogen 3.128 N/A LYS 40.A NZ PRO 37.A O no hydrogen 2.798 N/A ARG 42.A N ASN 39.A O no hydrogen 2.910 N/A ARG 42.A NH1 ASN 63.A O no hydrogen 3.507 N/A ARG 42.A NH1 TYR 65.A O no hydrogen 2.880 N/A ASN 43.A ND2 ALA 34.A O no hydrogen 2.949 N/A ARG 44.A N GLN 84.A OE1 no hydrogen 2.842 N/A ARG 44.A NE GLY 85.A O no hydrogen 3.017 N/A ARG 44.A NH2 GLY 85.A O no hydrogen 3.316 N/A ARG 44.A NH2 PRO 86.A O no hydrogen 2.726 N/A TYR 45.A OH SER 215.A OG no hydrogen 2.688 N/A VAL 48.A N TYR 45.A O no hydrogen 3.109 N/A ASP 52.A N PRO 30.A O no hydrogen 2.841 N/A HIS 53.A NE2 LYS 254.A O no hydrogen 2.844 N/A SER 54.A N PHE 51.A O no hydrogen 3.372 N/A SER 54.A OG PHE 255.A O no hydrogen 2.650 N/A ARG 55.A NH1 ASP 64.A OD1 no hydrogen 2.922 N/A ARG 55.A NH2 ASP 64.A OD1 no hydrogen 3.214 N/A ARG 55.A NH2 ASP 64.A OD2 no hydrogen 3.033 N/A ILE 56.A N ALA 68.A O no hydrogen 3.012 N/A LEU 58.A N ASP 64.A O no hydrogen 2.807 N/A HIS 59.A N GLU 100.A OE1 no hydrogen 2.899 N/A GLN 60.A N GLU 96.A OE2 no hydrogen 3.139 N/A GLN 60.A NE2 THR 137.A O no hydrogen 3.302 N/A ASN 63.A ND2 ASN 39.A OD1 no hydrogen 2.839 N/A TYR 65.A N ASN 63.A OD1 no hydrogen 2.988 N/A TYR 65.A OH ASN 43.A OD1 no hydrogen 2.667 N/A ASN 67.A ND2 ASN 43.A OD1 no hydrogen 2.927 N/A ASN 67.A ND2 VAL 48.A O no hydrogen 2.960 N/A SER 69.A N LEU 82.A O no hydrogen 2.864 N/A LEU 70.A N SER 54.A O no hydrogen 2.862 N/A ILE 71.A N TYR 80.A O no hydrogen 2.774 N/A MET 73.A N ARG 78.A O no hydrogen 2.957 N/A GLN 77.A N MET 73.A O no hydrogen 2.911 N/A GLN 77.A N GLU 74.A O no hydrogen 3.244 N/A ARG 78.A N MET 73.A O no hydrogen 3.292 N/A ARG 78.A NH1 ASP 228.A OD2 no hydrogen 2.857 N/A TYR 80.A N ILE 71.A O no hydrogen 2.982 N/A TYR 80.A OH ASP 228.A OD2 no hydrogen 2.647 N/A TYR 80.A OH THR 229.A OG1 no hydrogen 3.056 N/A ILE 81.A N VAL 210.A O no hydrogen 2.844 N/A LEU 82.A N SER 69.A O no hydrogen 2.968 N/A THR 83.A N VAL 212.A O no hydrogen 3.009 N/A THR 83.A OG1 ASN 67.A O no hydrogen 2.610 N/A GLN 84.A N ASN 67.A O no hydrogen 3.362 N/A GLN 84.A NE2 ARG 42.A O no hydrogen 2.920 N/A GLY 85.A N SER 215.A O no hydrogen 2.829 N/A LEU 87.A N THR 90.A OG1 no hydrogen 2.882 N/A ASN 89.A ND2 ASN 41.A O.A no hydrogen 2.914 N/A ASN 89.A ND2 ASN 41.A O.B no hydrogen 3.018 N/A THR 90.A N LEU 87.A O no hydrogen 2.962 N/A THR 90.A OG1 LEU 87.A O no hydrogen 3.528 N/A CYS 91.A SG LEU 87.A O no hydrogen 3.387 N/A PHE 94.A N THR 90.A O no hydrogen 2.897 N/A TRP 95.A N CYS 91.A O no hydrogen 3.093 N/A TRP 95.A NE1 TYR 123.A O no hydrogen 2.908 N/A GLU 96.A N GLY 92.A O no hydrogen 2.890 N/A MET 97.A N HIS 93.A O no hydrogen 2.856 N/A VAL 98.A N PHE 94.A O no hydrogen 2.983 N/A TRP 99.A N TRP 95.A O no hydrogen 2.907 N/A GLU 100.A N GLU 96.A O no hydrogen 2.832 N/A GLN 101.A N MET 97.A O no hydrogen 2.859 N/A LYS 102.A N TRP 99.A O no hydrogen 3.123 N/A SER 103.A N VAL 98.A O no hydrogen 3.205 N/A SER 103.A OG PRO 209.A O no hydrogen 2.681 N/A ARG 104.A NH1 GLU 169.A O no hydrogen 2.927 N/A ARG 104.A NH1 GLU 169.A OE1 no hydrogen 2.875 N/A ARG 104.A NH2 GLU 169.A OE1 no hydrogen 3.241 N/A VAL 106.A N LEU 171.A O no hydrogen 2.964 N/A VAL 107.A N VAL 211.A O no hydrogen 2.732 N/A MET 108.A N PHE 173.A O no hydrogen 2.878 N/A LEU 109.A N HIS 213.A O no hydrogen 3.044 N/A ASN 110.A ND2 ARG 111.A O no hydrogen 2.907 N/A ARG 111.A N GLU 114.A OE2 no hydrogen 2.926 N/A ARG 111.A NH1 THR 176.A O no hydrogen 2.941 N/A ARG 111.A NH1 TRP 178.A O no hydrogen 2.836 N/A ARG 111.A NH2 TRP 178.A O no hydrogen 3.036 N/A ARG 111.A NH2 ASP 180.A OD1 no hydrogen 2.841 N/A GLU 114.A N SER 117.A O no hydrogen 2.937 N/A SER 117.A N GLU 114.A O no hydrogen 3.004 N/A LYS 119.A N VAL 112.A O no hydrogen 2.784 N/A LYS 119.A NZ GLU 114.A OE1 no hydrogen 3.034 N/A CYS 120.A SG.A ALA 121.A O no hydrogen 3.435 N/A CYS 120.A SG.B ALA 121.A O no hydrogen 3.562 N/A ALA 121.A N PRO 86.A O no hydrogen 2.876 N/A GLN 122.A NE2 TRP 124.A O no hydrogen 2.938 N/A TYR 123.A OH HIS 213.A NE2 no hydrogen 2.589 N/A GLU 128.A N GLU 128.A OE1 no hydrogen 2.729 N/A GLU 129.A N GLU 129.A OE1 no hydrogen 2.738 N/A LYS 130.A N LYS 127.A O no hydrogen 3.013 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.774 N/A MET 132.A N LEU 141.A O no hydrogen 2.890 N/A PHE 134.A N LEU 139.A O no hydrogen 2.797 N/A THR 137.A OG1 GLY 92.A O no hydrogen 3.078 N/A ASN 138.A ND2 THR 163.A OG1 no hydrogen 2.876 N/A LEU 139.A N PHE 134.A O no hydrogen 3.215 N/A LYS 140.A N GLU 160.A O no hydrogen 2.931 N/A LEU 141.A N MET 132.A O no hydrogen 2.824 N/A THR 142.A N GLU 158.A O no hydrogen 2.950 N/A ILE 144.A N GLN 156.A O no hydrogen 2.897 N/A SER 145.A N GLN 156.A O no hydrogen 3.410 N/A SER 145.A OG GLN 156.A OE1.A no hydrogen 2.964 N/A SER 145.A OG GLN 156.A OE1.B no hydrogen 2.385 N/A ASP 147.A N VAL 154.A O no hydrogen 2.791 N/A LYS 149.A N TYR 152.A O no hydrogen 2.904 N/A LYS 149.A NZ ASP 147.A OD1 no hydrogen 3.167 N/A LYS 149.A NZ ASP 147.A OD2 no hydrogen 3.113 N/A THR 153.A N HIS 174.A O no hydrogen 2.882 N/A VAL 154.A N ASP 147.A O no hydrogen 2.977 N/A ARG 155.A N HIS 172.A O no hydrogen 2.893 N/A ARG 155.A NE GLU 146.A OE1 no hydrogen 2.857 N/A ARG 155.A NH1 HIS 172.A ND1 no hydrogen 2.904 N/A ARG 155.A NH1 HIS 174.A ND1 no hydrogen 3.045 N/A ARG 155.A NH2 HIS 174.A ND1 no hydrogen 3.412 N/A GLN 156.A N SER 145.A O no hydrogen 2.856 N/A LEU 157.A N ILE 170.A O no hydrogen 2.886 N/A GLU 158.A N THR 142.A O no hydrogen 2.849 N/A LEU 159.A N ARG 168.A O no hydrogen 2.898 N/A GLU 160.A N LYS 140.A O no hydrogen 2.784 N/A ASN 161.A N GLU 166.A O no hydrogen 2.913 N/A LEU 162.A N ASN 138.A O no hydrogen 2.914 N/A THR 163.A N ASN 161.A OD1 no hydrogen 2.963 N/A THR 164.A OG1 GLU 166.A OE1.B no hydrogen 2.863 N/A GLN 165.A N ASN 161.A O no hydrogen 2.743 N/A GLU 166.A N THR 164.A OG1 no hydrogen 3.177 N/A ARG 168.A N LEU 159.A O no hydrogen 2.872 N/A ARG 168.A NE GLU 166.A OE2.A no hydrogen 3.107 N/A ARG 168.A NH1 TRP 99.A O no hydrogen 2.833 N/A ARG 168.A NH2 GLU 166.A OE2.A no hydrogen 3.495 N/A ILE 170.A N LEU 157.A O no hydrogen 2.885 N/A LEU 171.A N ARG 104.A O no hydrogen 2.923 N/A HIS 172.A N ARG 155.A O no hydrogen 2.866 N/A HIS 172.A NE2 TYR 123.A OH no hydrogen 2.791 N/A PHE 173.A N VAL 106.A O no hydrogen 2.768 N/A HIS 174.A N THR 153.A O no hydrogen 2.833 N/A HIS 174.A NE2 ASN 110.A O no hydrogen 2.788 N/A TYR 175.A N MET 108.A O no hydrogen 2.856 N/A TYR 175.A OH SER 189.A OG.A no hydrogen 2.612 N/A THR 176.A N TYR 151.A O no hydrogen 3.169 N/A THR 177.A OG1 TYR 151.A O no hydrogen 3.154 N/A TRP 178.A NE1 GLY 182.A O no hydrogen 3.119 N/A ALA 188.A N SER 186.A OG no hydrogen 3.141 N/A SER 189.A OG.A TYR 175.A OH no hydrogen 2.612 N/A LEU 191.A N PRO 187.A O no hydrogen 2.854 N/A ASN 192.A N ALA 188.A O no hydrogen 2.933 N/A PHE 193.A N SER 189.A O no hydrogen 2.881 N/A LEU 194.A N PHE 190.A O no hydrogen 2.836 N/A PHE 195.A N LEU 191.A O no hydrogen 2.873 N/A LYS 196.A N ASN 192.A O no hydrogen 2.916 N/A VAL 197.A N PHE 193.A O no hydrogen 2.992 N/A ARG 198.A N LEU 194.A O no hydrogen 3.207 N/A ARG 198.A NE ASP 228.A OD1 no hydrogen 2.819 N/A ARG 198.A NH2 ASP 228.A O no hydrogen 3.051 N/A ARG 198.A NH2 ASP 228.A OD1 no hydrogen 3.282 N/A GLU 199.A N PHE 195.A O no hydrogen 2.837 N/A SER 200.A N LYS 196.A O no hydrogen 3.110 N/A SER 200.A N VAL 197.A O no hydrogen 3.275 N/A SER 200.A OG VAL 197.A O no hydrogen 2.645 N/A SER 200.A OG SER 202.A OG no hydrogen 2.814 N/A GLY 201.A N ARG 198.A O no hydrogen 3.168 N/A SER 202.A N SER 200.A OG no hydrogen 3.045 N/A SER 202.A OG SER 200.A OG no hydrogen 2.814 N/A SER 204.A N GLY 201.A O no hydrogen 3.087 N/A GLU 206.A N SER 204.A OG no hydrogen 3.110 N/A HIS 207.A N SER 204.A O no hydrogen 3.009 N/A GLY 208.A N LYS 102.A O no hydrogen 2.893 N/A VAL 211.A N GLY 105.A O no hydrogen 3.141 N/A VAL 212.A N ILE 81.A O no hydrogen 2.762 N/A HIS 213.A N VAL 107.A O no hydrogen 2.893 N/A HIS 213.A ND1 CYS 214.A O no hydrogen 2.926 N/A HIS 213.A NE2 TYR 123.A OH no hydrogen 2.589 N/A CYS 214.A SG SER 221.A OG no hydrogen 3.088 N/A SER 215.A OG TYR 45.A OH no hydrogen 2.688 N/A SER 215.A OG LYS 119.A O no hydrogen 2.799 N/A ARG 220.A NH1 LEU 109.A O no hydrogen 2.982 N/A ARG 220.A NH1 GLU 114.A OE1 no hydrogen 3.552 N/A ARG 220.A NH1 GLU 114.A OE2 no hydrogen 2.934 N/A ARG 220.A NH2 GLU 114.A OE1 no hydrogen 2.831 N/A THR 223.A N GLY 219.A O no hydrogen 2.965 N/A THR 223.A OG1.A GLY 219.A O no hydrogen 3.186 N/A THR 223.A OG1.B ARG 220.A O no hydrogen 2.748 N/A TYR 224.A N ARG 220.A O no hydrogen 3.014 N/A CYS 225.A N SER 221.A O no hydrogen 3.052 N/A CYS 225.A SG.B SER 221.A O no hydrogen 3.411 N/A LEU 226.A N GLY 222.A O no hydrogen 2.818 N/A ALA 227.A N THR 223.A O no hydrogen 2.922 N/A ASP 228.A N TYR 224.A O no hydrogen 2.939 N/A THR 229.A N CYS 225.A O no hydrogen 2.881 N/A THR 229.A OG1 TYR 80.A OH no hydrogen 3.056 N/A THR 229.A OG1 CYS 225.A O no hydrogen 2.984 N/A CYS 230.A N LEU 226.A O no hydrogen 2.943 N/A CYS 230.A SG LEU 226.A O no hydrogen 3.366 N/A LEU 231.A N ALA 227.A O no hydrogen 2.994 N/A LEU 232.A N ASP 228.A O no hydrogen 3.081 N/A LEU 233.A N THR 229.A O no hydrogen 2.918 N/A MET 234.A N CYS 230.A O no hydrogen 2.984 N/A ASP 235.A N LEU 231.A O no hydrogen 3.262 N/A LYS 236.A N LEU 233.A O no hydrogen 3.238 N/A LYS 236.A NZ GLN 77.A OE1 no hydrogen 3.011 N/A ARG 237.A N LEU 233.A O no hydrogen 2.829 N/A ARG 237.A NE GLU 75.A OE2 no hydrogen 2.676 N/A ARG 237.A NH1 SER 242.A OG no hydrogen 3.010 N/A ARG 237.A NH2 GLU 75.A OE1 no hydrogen 2.845 N/A ARG 237.A NH2 GLU 75.A OE2 no hydrogen 3.446 N/A SER 242.A N ASP 239.A O no hydrogen 3.010 N/A SER 242.A OG ASP 239.A O no hydrogen 2.790 N/A VAL 243.A N PRO 240.A O no hydrogen 3.393 N/A LYS 246.A NZ GLU 25.A OE1 no hydrogen 3.364 N/A LYS 246.A NZ GLU 25.A OE2 no hydrogen 2.947 N/A LYS 247.A N ASP 244.A OD1 no hydrogen 3.336 N/A VAL 248.A N ASP 244.A O no hydrogen 2.991 N/A LEU 249.A N ILE 245.A O no hydrogen 2.881 N/A LEU 250.A N LYS 246.A O no hydrogen 2.953 N/A GLU 251.A N LYS 247.A O no hydrogen 2.960 N/A MET 252.A N VAL 248.A O no hydrogen 2.912 N/A ARG 253.A N LEU 249.A O no hydrogen 2.909 N/A ARG 253.A NE LEU 259.A O no hydrogen 2.836 N/A ARG 253.A NH2 LEU 259.A O no hydrogen 2.962 N/A ARG 253.A NH2 ILE 260.A O no hydrogen 2.900 N/A LYS 254.A N GLU 251.A O no hydrogen 3.018 N/A LYS 254.A NZ GLU 251.A OE1 no hydrogen 2.693 N/A PHE 255.A N MET 252.A O no hydrogen 2.881 N/A ARG 256.A N MET 252.A O no hydrogen 3.411 N/A ARG 256.A NE GLY 217.A O no hydrogen 3.001 N/A ARG 256.A NH1 ASN 67.A OD1 no hydrogen 3.097 N/A ARG 256.A NH1 SER 69.A OG no hydrogen 2.970 N/A ARG 256.A NH2 ASN 67.A OD1 no hydrogen 2.957 N/A ARG 256.A NH2 ALA 216.A O no hydrogen 2.991 N/A ILE 260.A N ILE 218.A O no hydrogen 2.942 N/A GLN 261.A N GLN 265.A OE1 no hydrogen 2.792 N/A GLN 261.A NE2.A GLY 258.A O no hydrogen 2.817 N/A GLN 265.A N THR 262.A OG1 no hydrogen 2.931 N/A LEU 266.A N THR 262.A O no hydrogen 3.049 N/A ARG 267.A N ALA 263.A O no hydrogen 2.924 N/A ARG 267.A NE ASP 10.A OD1 no hydrogen 2.929 N/A ARG 267.A NH2 ASP 10.A OD2 no hydrogen 2.914 N/A PHE 268.A N ASP 264.A O no hydrogen 2.846 N/A SER 269.A N GLN 265.A O no hydrogen 2.916 N/A SER 269.A OG GLN 265.A O no hydrogen 2.805 N/A TYR 270.A N LEU 266.A O no hydrogen 3.099 N/A LEU 271.A N ARG 267.A O no hydrogen 2.919 N/A ALA 272.A N PHE 268.A O no hydrogen 2.791 N/A VAL 273.A N SER 269.A O no hydrogen 2.976 N/A ILE 274.A N TYR 270.A O no hydrogen 2.924 N/A GLU 275.A N LEU 271.A O no hydrogen 3.037 N/A GLY 276.A N ALA 272.A O no hydrogen 2.784 N/A ALA 277.A N VAL 273.A O no hydrogen 2.831 N/A LYS 278.A N ILE 274.A O no hydrogen 3.299 N/A LYS 278.A NZ GLU 3.A OE2 no hydrogen 3.070 N/A LYS 278.A NZ GLU 275.A OE2 no hydrogen 3.125 N/A PHE 279.A N GLU 275.A O no hydrogen 3.286 N/A ILE 280.A N GLY 276.A O no hydrogen 3.118 N/A