Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7nc4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 3.A N ASP 8.A O no hydrogen 2.998 N/A GLY 5.A N ASP 8.A OD1 no hydrogen 2.773 N/A GLN 6.A NE2 GLN 6.A O no hydrogen 3.547 N/A HIS 12.A N GLY 9.A O no hydrogen 2.875 N/A TRP 13.A N PRO 10.A O no hydrogen 3.395 N/A TRP 13.A NE1 GLY 3.A O no hydrogen 3.146 N/A TRP 13.A NE1 ASP 8.A O no hydrogen 3.075 N/A LYS 15.A N HIS 12.A O no hydrogen 2.989 N/A LYS 15.A NZ HIS 12.A ND1 no hydrogen 2.787 N/A LEU 16.A N TRP 13.A O no hydrogen 2.893 N/A TYR 17.A N TRP 13.A O no hydrogen 2.865 N/A ALA 20.A N TYR 17.A O no hydrogen 2.961 N/A GLN 21.A N PRO 18.A O no hydrogen 3.119 N/A GLN 21.A NE2 PRO 18.A O no hydrogen 3.167 N/A GLY 22.A N ILE 19.A O no hydrogen 2.799 N/A ARG 24.A N GLU 202.A OE2 no hydrogen 2.933 N/A ARG 24.A NH2 GLU 202.A O no hydrogen 2.930 N/A GLN 25.A NE2 LEU 200.A O no hydrogen 3.135 N/A GLN 25.A NE2 GLU 202.A OE2 no hydrogen 3.047 N/A SER 26.A N SER 194.A OG no hydrogen 2.925 N/A SER 26.A OG TYR 191.A OH no hydrogen 2.932 N/A SER 26.A OG SER 194.A O no hydrogen 3.482 N/A ILE 30.A N THR 105.A O no hydrogen 2.794 N/A SER 32.A N ASP 107.A OD1 no hydrogen 3.007 N/A SER 32.A OG ASP 107.A OD1 no hydrogen 3.385 N/A SER 32.A OG ASP 107.A OD2 no hydrogen 2.631 N/A GLN 34.A N ILE 31.A O no hydrogen 2.912 N/A ALA 35.A N SER 32.A O no hydrogen 3.216 N/A VAL 36.A N VAL 253.A O no hydrogen 2.775 N/A SER 38.A N ALA 255.A O no hydrogen 2.871 N/A SER 38.A OG VAL 36.A O no hydrogen 3.123 N/A LEU 41.A N SER 38.A O no hydrogen 3.283 N/A GLU 45.A N THR 77.A O no hydrogen 2.850 N/A SER 47.A N.A VAL 75.A O no hydrogen 2.949 N/A SER 47.A N.B VAL 75.A O no hydrogen 2.956 N/A TYR 48.A OH HIS 119.A NE2 no hydrogen 2.702 N/A GLU 49.A N THR 74.A OG1 no hydrogen 3.403 N/A SER 53.A OG PHE 173.A O no hydrogen 2.720 N/A LEU 54.A N ASP 66.A O no hydrogen 2.778 N/A ILE 56.A N ALA 171.A O no hydrogen 2.903 N/A THR 57.A N GLN 64.A O no hydrogen 2.774 N/A ASN 58.A N THR 169.A O no hydrogen 2.972 N/A ASN 58.A ND2 VAL 164.A O no hydrogen 3.062 N/A ASN 58.A ND2 LEU 227.A O no hydrogen 3.108 N/A ASN 59.A N SER 62.A O no hydrogen 3.252 N/A GLY 60.A N ASN 58.A OD1 no hydrogen 2.766 N/A HIS 61.A N ASN 59.A OD1 no hydrogen 2.838 N/A HIS 61.A NE2 TRP 2.A O no hydrogen 3.274 N/A SER 62.A N ASN 59.A OD1 no hydrogen 2.968 N/A SER 62.A OG VAL 63.A O no hydrogen 3.344 N/A SER 62.A OG PHE 92.A O no hydrogen 2.592 N/A GLN 64.A N THR 57.A O no hydrogen 2.814 N/A GLN 64.A NE2 ASP 66.A OD1 no hydrogen 2.953 N/A VAL 65.A N PHE 90.A O no hydrogen 2.859 N/A ASP 66.A N SER 55.A O no hydrogen 3.115 N/A PHE 67.A N LYS 88.A O no hydrogen 2.953 N/A ASN 68.A N MET 52.A O no hydrogen 2.906 N/A SER 70.A N ASN 68.A OD1 no hydrogen 2.988 N/A SER 70.A OG ASN 68.A OD1 no hydrogen 2.621 N/A ARG 73.A N ASP 71.A OD1 no hydrogen 2.808 N/A ARG 73.A NE ASP 71.A OD1 no hydrogen 3.382 N/A ARG 73.A NE ASP 71.A OD2 no hydrogen 3.076 N/A VAL 75.A N SER 47.A O.A no hydrogen 3.043 N/A VAL 75.A N SER 47.A O.B no hydrogen 3.052 N/A VAL 76.A N TYR 85.A O no hydrogen 2.970 N/A THR 77.A N GLU 45.A O no hydrogen 2.903 N/A GLY 79.A N GLN 42.A O no hydrogen 2.723 N/A LEU 81.A N GLY 78.A O no hydrogen 2.998 N/A TYR 85.A N VAL 76.A O no hydrogen 3.032 N/A TYR 85.A OH ASP 136.A O no hydrogen 2.969 N/A ARG 86.A N TRP 120.A O no hydrogen 2.893 N/A ARG 86.A NE ASP 72.A OD1 no hydrogen 2.735 N/A ARG 86.A NH1 ASP 69.A O no hydrogen 2.913 N/A LEU 87.A N THR 74.A O no hydrogen 2.867 N/A LYS 88.A N VAL 118.A O no hydrogen 2.801 N/A LYS 88.A NZ ASP 69.A OD2 no hydrogen 3.393 N/A GLN 89.A N VAL 118.A O no hydrogen 3.473 N/A PHE 90.A N VAL 65.A O no hydrogen 2.917 N/A HIS 91.A N HIS 116.A O no hydrogen 3.044 N/A HIS 91.A ND1 GLN 89.A OE1 no hydrogen 2.786 N/A PHE 92.A N SER 62.A OG no hydrogen 3.196 N/A HIS 93.A N GLU 114.A O no hydrogen 2.923 N/A HIS 93.A ND1 ASN 241.A O no hydrogen 2.822 N/A HIS 93.A NE2 HIS 116.A ND1 no hydrogen 3.059 N/A TRP 94.A N ASN 241.A OD1 no hydrogen 2.821 N/A TRP 94.A NE1 MET 238.A O no hydrogen 2.803 N/A GLY 95.A N PRO 112.A O no hydrogen 3.190 N/A LYS 96.A N ASN 240.A OD1 no hydrogen 3.095 N/A HIS 98.A NE2 GLU 146.A OE1 no hydrogen 2.530 N/A VAL 100.A N LYS 97.A O no hydrogen 3.192 N/A SER 102.A N PHE 111.A O no hydrogen 2.794 N/A SER 102.A OG HIS 104.A O no hydrogen 2.803 N/A SER 102.A OG PHE 111.A O no hydrogen 3.459 N/A GLU 103.A N GLU 114.A OE1 no hydrogen 2.832 N/A HIS 104.A N GLU 114.A OE1 no hydrogen 2.818 N/A HIS 104.A ND1 GLU 114.A OE2 no hydrogen 2.773 N/A HIS 104.A NE2 TYR 191.A OH no hydrogen 2.639 N/A THR 105.A N ILE 28.A O no hydrogen 3.292 N/A THR 105.A OG1 ASN 29.A OD1 no hydrogen 2.640 N/A VAL 106.A N LYS 109.A O no hydrogen 2.984 N/A ASP 107.A N ILE 30.A O no hydrogen 2.765 N/A GLY 108.A N ASN 29.A OD1 no hydrogen 2.859 N/A LYS 109.A N VAL 106.A O no hydrogen 2.892 N/A PHE 111.A N SER 102.A OG no hydrogen 2.910 N/A SER 113.A OG HIS 93.A O no hydrogen 2.885 N/A GLU 114.A N HIS 93.A O no hydrogen 2.890 N/A LEU 115.A N VAL 143.A O no hydrogen 2.779 N/A HIS 116.A N HIS 91.A O no hydrogen 2.901 N/A HIS 116.A NE2 GLU 114.A OE2 no hydrogen 2.702 N/A LEU 117.A N VAL 141.A O no hydrogen 2.911 N/A VAL 118.A N GLN 89.A O no hydrogen 2.860 N/A HIS 119.A N ALA 139.A O no hydrogen 2.908 N/A HIS 119.A ND1 ALA 139.A O no hydrogen 3.010 N/A HIS 119.A NE2 TYR 48.A OH no hydrogen 2.702 N/A TRP 120.A N ARG 86.A O no hydrogen 2.874 N/A TRP 120.A NE1 ASP 69.A OD2 no hydrogen 2.745 N/A ASN 121.A N GLY 137.A O no hydrogen 2.799 N/A ASN 121.A ND2 ASP 136.A O no hydrogen 3.244 N/A LYS 123.A NZ ASP 72.A OD2 no hydrogen 2.884 N/A LYS 124.A N ASN 121.A O no hydrogen 3.384 N/A LYS 124.A N ASN 121.A OD1 no hydrogen 3.283 N/A LYS 124.A NZ ASP 136.A OD2 no hydrogen 2.639 N/A TYR 125.A N ASN 121.A O no hydrogen 3.061 N/A TYR 125.A OH ASP 136.A OD1 no hydrogen 2.555 N/A SER 126.A N GLU 130.A OE1 no hydrogen 2.974 N/A SER 126.A OG GLU 130.A OE1 no hydrogen 3.213 N/A ALA 131.A N THR 127.A O no hydrogen 2.970 N/A ALA 132.A N PHE 128.A O no hydrogen 2.779 N/A SER 133.A N GLU 130.A O no hydrogen 3.412 N/A SER 133.A OG GLU 130.A O no hydrogen 3.057 N/A ALA 134.A N ALA 131.A O no hydrogen 3.066 N/A GLY 137.A N ALA 134.A O no hydrogen 2.863 N/A LEU 138.A N SER 203.A O no hydrogen 2.925 N/A ALA 139.A N HIS 119.A O no hydrogen 2.912 N/A VAL 140.A N THR 205.A O no hydrogen 3.123 N/A VAL 141.A N LEU 117.A O no hydrogen 2.919 N/A GLY 142.A N ILE 207.A O no hydrogen 2.793 N/A VAL 143.A N LEU 115.A O no hydrogen 2.846 N/A LEU 145.A N SER 113.A O no hydrogen 2.940 N/A GLU 146.A N ILE 213.A O no hydrogen 2.826 N/A THR 147.A N GLU 146.A OE1 no hydrogen 3.122 N/A GLY 148.A N ILE 215.A O no hydrogen 2.799 N/A HIS 151.A N GLN 219.A OE1 no hydrogen 2.859 N/A MET 154.A N HIS 151.A ND1 no hydrogen 3.004 N/A ASN 155.A N PRO 152.A O no hydrogen 3.175 N/A ASN 155.A ND2 GLU 150.A OE2 no hydrogen 2.761 N/A ASN 155.A ND2 PRO 152.A O no hydrogen 3.583 N/A ARG 156.A N SER 153.A O no hydrogen 3.342 N/A ARG 156.A NH1 SER 174.A O no hydrogen 2.648 N/A ARG 156.A NH2 SER 174.A O no hydrogen 2.574 N/A LEU 157.A N MET 154.A O no hydrogen 2.787 N/A THR 158.A N MET 154.A O no hydrogen 2.862 N/A THR 158.A OG1 MET 154.A O no hydrogen 3.312 N/A THR 158.A OG1 ASN 155.A O no hydrogen 3.552 N/A ASP 159.A N ASN 155.A O no hydrogen 2.843 N/A ALA 160.A N LEU 157.A O no hydrogen 2.952 N/A LEU 161.A N THR 158.A O no hydrogen 3.318 N/A MET 163.A N ALA 160.A O no hydrogen 3.271 N/A VAL 164.A N LEU 161.A O no hydrogen 2.952 N/A ARG 165.A N TYR 162.A O no hydrogen 3.214 N/A ARG 165.A NH1 TYR 162.A O no hydrogen 2.868 N/A LYS 167.A N THR 229.A O no hydrogen 2.954 N/A GLY 168.A N ASN 58.A O no hydrogen 2.862 N/A THR 169.A OG1 PHE 166.A O no hydrogen 2.730 N/A ALA 171.A N ILE 56.A O no hydrogen 2.929 N/A PHE 173.A N LEU 54.A O no hydrogen 2.988 N/A PHE 176.A N SER 53.A OG no hydrogen 3.016 N/A LYS 179.A N ASN 177.A OD1 no hydrogen 2.842 N/A SER 180.A N ASN 177.A O no hydrogen 2.956 N/A SER 180.A OG ASN 177.A O no hydrogen 2.834 N/A LEU 181.A N PRO 178.A O no hydrogen 3.020 N/A LEU 182.A N LYS 179.A O no hydrogen 3.172 N/A ARG 186.A NH1 PRO 183.A O no hydrogen 2.881 N/A ARG 186.A NH1 SER 185.A O no hydrogen 3.247 N/A HIS 187.A N SER 185.A OG no hydrogen 3.210 N/A HIS 187.A ND1 SER 256.A OG no hydrogen 2.940 N/A TYR 188.A N SER 256.A OG no hydrogen 2.876 N/A TRP 189.A N VAL 208.A O no hydrogen 2.918 N/A THR 190.A N LYS 254.A O no hydrogen 2.829 N/A THR 190.A OG1 TRP 206.A O no hydrogen 2.700 N/A TYR 191.A N TRP 206.A O no hydrogen 3.277 N/A TYR 191.A OH SER 26.A OG no hydrogen 2.932 N/A TYR 191.A OH HIS 104.A NE2 no hydrogen 2.639 N/A GLY 193.A N VAL 204.A O no hydrogen 2.783 N/A SER 194.A N SER 26.A OG no hydrogen 2.889 N/A SER 194.A OG LEU 195.A O no hydrogen 2.823 N/A LEU 195.A N SER 201.A O no hydrogen 2.984 N/A THR 196.A OG1 GLU 103.A OE1 no hydrogen 2.586 N/A THR 196.A OG1 GLU 103.A OE2 no hydrogen 3.517 N/A THR 197.A OG1 PRO 198.A O no hydrogen 3.396 N/A LEU 200.A N THR 197.A O no hydrogen 2.832 N/A SER 203.A OG ALA 132.A O no hydrogen 2.740 N/A SER 203.A OG SER 201.A O no hydrogen 3.552 N/A VAL 204.A N GLY 193.A O no hydrogen 3.250 N/A THR 205.A N LEU 138.A O no hydrogen 2.897 N/A TRP 206.A N TYR 191.A O no hydrogen 3.055 N/A TRP 206.A NE1 SER 194.A O no hydrogen 2.893 N/A ILE 207.A N VAL 140.A O no hydrogen 2.976 N/A VAL 208.A N TRP 189.A O no hydrogen 2.867 N/A LEU 209.A N GLY 142.A O no hydrogen 2.894 N/A ARG 210.A N HIS 187.A O no hydrogen 2.967 N/A ILE 213.A N PHE 144.A O no hydrogen 2.874 N/A SER 214.A OG ASP 149.A O no hydrogen 3.443 N/A ILE 215.A N GLU 146.A O no hydrogen 3.006 N/A SER 216.A N GLN 219.A OE1 no hydrogen 2.957 N/A ARG 218.A NH2 GLU 150.A OE1 no hydrogen 3.337 N/A ARG 218.A NH2 ASN 155.A OD1 no hydrogen 2.909 N/A GLN 219.A N SER 216.A OG no hydrogen 3.020 N/A GLN 219.A NE2 HIS 151.A O no hydrogen 2.774 N/A GLN 219.A NE2 ASN 155.A OD1 no hydrogen 2.944 N/A MET 220.A N SER 216.A O no hydrogen 2.892 N/A GLY 221.A N GLU 217.A O no hydrogen 2.852 N/A LYS 222.A N ARG 218.A O no hydrogen 3.267 N/A LYS 222.A N GLN 219.A O no hydrogen 2.984 N/A PHE 223.A N MET 220.A O no hydrogen 3.044 N/A ARG 224.A N MET 220.A O no hydrogen 3.208 N/A ARG 224.A NE GLY 95.A O no hydrogen 2.908 N/A SER 225.A N LYS 222.A O no hydrogen 3.329 N/A SER 225.A OG GLY 221.A O no hydrogen 3.005 N/A LEU 226.A N PHE 223.A O no hydrogen 3.031 N/A LEU 227.A N ARG 165.A O no hydrogen 2.901 N/A PHE 228.A N ILE 236.A O no hydrogen 2.913 N/A SER 230.A OG ASP 233.A OD1 no hydrogen 2.531 N/A ASP 233.A N SER 230.A O no hydrogen 3.044 N/A ILE 236.A N THR 229.A OG1 no hydrogen 3.199 N/A MET 238.A N LEU 226.A O no hydrogen 2.852 N/A ASN 241.A N TRP 94.A O no hydrogen 3.299 N/A ASN 241.A ND2 HIS 61.A O no hydrogen 2.892 N/A ASN 241.A ND2 PHE 92.A O no hydrogen 3.636 N/A ARG 243.A N GLU 103.A OE2 no hydrogen 2.815 N/A ARG 243.A NH1 GLN 25.A OE1 no hydrogen 2.826 N/A ARG 243.A NH1 SER 26.A O no hydrogen 2.844 N/A ARG 243.A NH2 ALA 20.A O no hydrogen 3.258 N/A ARG 243.A NH2 GLN 25.A OE1 no hydrogen 3.324 N/A GLN 246.A N PRO 27.A O no hydrogen 2.795 N/A GLN 246.A NE2 PRO 244.A O no hydrogen 2.753 N/A LYS 249.A NZ GLN 21.A O no hydrogen 2.925 N/A LYS 249.A NZ GLY 22.A O no hydrogen 3.114 N/A ARG 251.A N LEU 248.A O no hydrogen 3.120 N/A ARG 251.A NE LEU 248.A O no hydrogen 2.852 N/A ARG 251.A NH1 GLN 25.A O no hydrogen 3.000 N/A ARG 251.A NH1 PRO 192.A O no hydrogen 2.882 N/A ARG 251.A NH2 GLN 25.A O no hydrogen 2.755 N/A ARG 251.A NH2 PRO 247.A O no hydrogen 2.890 N/A LYS 254.A N THR 190.A O no hydrogen 2.970 N/A ALA 255.A N VAL 36.A O no hydrogen 2.802 N/A SER 256.A N TYR 188.A O no hydrogen 2.929 N/A SER 256.A OG HIS 187.A ND1 no hydrogen 2.940 N/A SER 256.A OG TYR 188.A O no hydrogen 3.435 N/A