Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7nho_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N TRP 2.A O no hydrogen 2.987 N/A ASP 7.A N PHE 3.A O no hydrogen 2.870 N/A ASP 8.A N ASP 4.A O no hydrogen 2.948 N/A TRP 9.A N ILE 5.A O no hydrogen 2.932 N/A LEU 10.A N LEU 6.A O no hydrogen 3.078 N/A LYS 11.A N ASP 7.A O no hydrogen 2.866 N/A SER 21.A N GLU 119.A OE1 no hydrogen 3.365 N/A SER 21.A OG VAL 18.A O no hydrogen 3.519 N/A GLY 22.A N GLY 19.A O no hydrogen 3.197 N/A ILE 23.A N TRP 20.A O no hydrogen 3.279 N/A LEU 24.A N SER 21.A O no hydrogen 3.051 N/A LEU 25.A N SER 21.A O no hydrogen 2.857 N/A PHE 26.A N GLY 22.A O no hydrogen 2.948 N/A CYS 28.A SG LEU 24.A O no hydrogen 3.277 N/A ALA 29.A N LEU 25.A O no hydrogen 2.973 N/A TYR 30.A N PHE 26.A O no hydrogen 2.997 N/A LEU 31.A N PRO 27.A O no hydrogen 2.913 N/A ALA 32.A N CYS 28.A O no hydrogen 3.115 N/A LEU 33.A N ALA 29.A O no hydrogen 3.143 N/A GLY 34.A N TYR 30.A O no hydrogen 2.925 N/A GLY 35.A N LEU 31.A O no hydrogen 2.741 N/A TRP 36.A N ALA 32.A O no hydrogen 3.070 N/A TRP 36.A NE1 PHE 161.A O no hydrogen 3.267 N/A LEU 37.A N LEU 33.A O no hydrogen 2.937 N/A THR 38.A N GLY 34.A O no hydrogen 2.946 N/A GLY 39.A N GLY 35.A O no hydrogen 2.885 N/A THR 40.A N TRP 36.A O no hydrogen 2.906 N/A THR 40.A OG1 TRP 36.A O no hydrogen 3.028 N/A THR 40.A OG1 LEU 37.A O no hydrogen 3.303 N/A THR 41.A N THR 38.A O no hydrogen 3.156 N/A THR 41.A OG1 LEU 37.A O no hydrogen 2.825 N/A PHE 42.A N THR 38.A O no hydrogen 3.008 N/A THR 44.A OG1 GLU 57.A OE1 no hydrogen 2.843 N/A THR 44.A OG1 GLU 57.A OE2 no hydrogen 3.490 N/A SER 45.A OG SER 53.A OG no hydrogen 3.117 N/A TRP 46.A N THR 44.A OG1 no hydrogen 3.080 N/A HIS 49.A N SER 45.A O no hydrogen 3.282 N/A GLY 50.A N SER 45.A O no hydrogen 3.272 N/A LEU 51.A N SER 45.A O no hydrogen 3.328 N/A SER 53.A OG SER 45.A OG no hydrogen 3.117 N/A SER 53.A OG ALA 65.A O no hydrogen 3.330 N/A SER 54.A OG VAL 43.A O no hydrogen 3.283 N/A SER 54.A OG GLU 57.A OE2 no hydrogen 2.861 N/A TYR 55.A N THR 40.A O no hydrogen 3.380 N/A LEU 56.A N THR 41.A O no hydrogen 3.134 N/A GLU 57.A N SER 54.A O no hydrogen 3.098 N/A GLY 58.A N SER 54.A O no hydrogen 3.148 N/A GLY 58.A N TYR 55.A O no hydrogen 3.043 N/A CYS 59.A N SER 54.A O no hydrogen 3.129 N/A CYS 59.A SG SER 54.A O no hydrogen 3.603 N/A LEU 62.A N ASN 60.A OD1 no hydrogen 3.030 N/A THR 63.A N ASN 60.A O no hydrogen 3.444 N/A THR 63.A OG1 ASN 60.A OD1 no hydrogen 2.953 N/A ALA 65.A N SER 53.A O no hydrogen 3.481 N/A VAL 66.A N PHE 161.A O no hydrogen 3.125 N/A THR 68.A OG1 HIS 49.A NE2 no hydrogen 3.260 N/A ASN 71.A ND2 SER 154.A OG no hydrogen 3.045 N/A GLY 74.A N ASN 71.A O no hydrogen 3.221 N/A HIS 75.A NE2 PRO 149.A O no hydrogen 2.887 N/A SER 76.A N MET 73.A O no hydrogen 3.061 N/A SER 76.A OG GLU 84.A OE1 no hydrogen 3.442 N/A GLY 82.A N LEU 79.A O no hydrogen 2.987 N/A ALA 85.A N GLY 82.A O no hydrogen 3.184 N/A GLN 86.A N GLY 82.A O no hydrogen 2.823 N/A GLY 87.A N LEU 80.A O no hydrogen 3.323 N/A TRP 92.A NE1 LEU 78.A O no hydrogen 2.949 N/A CYS 93.A N PHE 89.A O no hydrogen 3.012 N/A CYS 93.A SG PHE 89.A O no hydrogen 3.208 N/A GLN 94.A N THR 90.A O no hydrogen 3.079 N/A LEU 95.A N ARG 91.A O no hydrogen 2.922 N/A GLY 97.A N TRP 92.A O no hydrogen 2.926 N/A THR 100.A OG1 LEU 77.A O no hydrogen 2.888 N/A THR 100.A OG1 GLY 97.A O no hydrogen 2.941 N/A PHE 101.A N GLY 97.A O no hydrogen 2.968 N/A ILE 102.A N LEU 98.A O no hydrogen 2.869 N/A ALA 103.A N TRP 99.A O no hydrogen 2.870 N/A LEU 104.A N THR 100.A O no hydrogen 2.895 N/A HIS 105.A N PHE 101.A O no hydrogen 2.996 N/A HIS 105.A ND1 PHE 101.A O no hydrogen 2.877 N/A GLY 106.A N ILE 102.A O no hydrogen 2.832 N/A ALA 107.A N ALA 103.A O no hydrogen 2.884 N/A PHE 108.A N LEU 104.A O no hydrogen 3.028 N/A GLY 109.A N HIS 105.A O no hydrogen 2.975 N/A LEU 110.A N GLY 106.A O no hydrogen 2.995 N/A GLY 112.A N PHE 108.A O no hydrogen 2.924 N/A PHE 113.A N GLY 109.A O no hydrogen 3.020 N/A MET 114.A N LEU 110.A O no hydrogen 3.013 N/A LEU 115.A N ILE 111.A O no hydrogen 2.932 N/A ARG 116.A N GLY 112.A O no hydrogen 2.850 N/A GLN 117.A N PHE 113.A O no hydrogen 2.920 N/A PHE 118.A N MET 114.A O no hydrogen 3.189 N/A GLU 119.A N LEU 115.A O no hydrogen 2.922 N/A ILE 120.A N ARG 116.A O no hydrogen 2.951 N/A ALA 121.A N GLN 117.A O no hydrogen 3.057 N/A ARG 122.A N PHE 118.A O no hydrogen 2.908 N/A ARG 122.A NE ARG 122.A O no hydrogen 2.870 N/A LEU 123.A N GLU 119.A O no hydrogen 2.963 N/A VAL 124.A N ILE 120.A O no hydrogen 2.909 N/A GLY 125.A N ALA 121.A O no hydrogen 3.084 N/A VAL 126.A N ALA 121.A O no hydrogen 3.285 N/A ALA 133.A N TYR 129.A O no hydrogen 2.966 N/A PHE 134.A N ASN 130.A O no hydrogen 2.992 N/A SER 135.A N ILE 132.A O no hydrogen 3.194 N/A SER 135.A OG ILE 132.A O no hydrogen 2.901 N/A ALA 136.A N ALA 133.A O no hydrogen 3.519 N/A ALA 139.A N SER 135.A O no hydrogen 2.958 N/A VAL 140.A N ALA 136.A O no hydrogen 2.994 N/A PHE 141.A N PRO 137.A O no hydrogen 2.835 N/A VAL 142.A N ILE 138.A O no hydrogen 2.983 N/A SER 143.A N ALA 139.A O no hydrogen 2.989 N/A SER 143.A OG ALA 139.A O no hydrogen 3.074 N/A SER 143.A OG VAL 140.A O no hydrogen 3.037 N/A VAL 144.A N VAL 140.A O no hydrogen 2.957 N/A PHE 145.A N PHE 141.A O no hydrogen 2.844 N/A ILE 147.A N VAL 142.A O no hydrogen 2.865 N/A TYR 148.A N SER 143.A O no hydrogen 3.263 N/A LEU 150.A N LEU 146.A O no hydrogen 3.272 N/A GLY 151.A N ILE 147.A O no hydrogen 2.907 N/A GLN 152.A N TYR 148.A O no hydrogen 3.379 N/A GLN 152.A N PRO 149.A O no hydrogen 3.218 N/A GLN 152.A NE2 ASN 280.A OD1 no hydrogen 3.271 N/A TRP 155.A NE1 SER 76.A O no hydrogen 2.769 N/A PHE 156.A N SER 154.A OG no hydrogen 3.394 N/A ALA 158.A N TRP 155.A O no hydrogen 3.175 N/A ILE 166.A N GLY 162.A O no hydrogen 3.339 N/A PHE 167.A N VAL 163.A O no hydrogen 3.081 N/A ARG 168.A N ALA 164.A O no hydrogen 2.878 N/A ARG 168.A NH2 ASP 321.A OD1 no hydrogen 3.288 N/A PHE 169.A N ALA 165.A O no hydrogen 3.157 N/A LEU 170.A N ILE 166.A O no hydrogen 2.943 N/A LEU 171.A N PHE 167.A O no hydrogen 3.077 N/A PHE 172.A N ARG 168.A O no hydrogen 2.884 N/A PHE 173.A N PHE 169.A O no hydrogen 2.887 N/A GLN 174.A N LEU 170.A O no hydrogen 2.995 N/A GLN 174.A NE2 ASN 178.A OD1 no hydrogen 3.090 N/A GLY 175.A N LEU 171.A O no hydrogen 2.868 N/A PHE 176.A N PHE 172.A O no hydrogen 2.985 N/A HIS 177.A N PHE 173.A O no hydrogen 3.019 N/A ASN 178.A N GLN 174.A O no hydrogen 3.225 N/A LEU 181.A N ASN 178.A O no hydrogen 3.239 N/A ASN 182.A N TRP 179.A O no hydrogen 3.488 N/A PHE 184.A N ASN 182.A OD1 no hydrogen 3.302 N/A MET 186.A N ASN 182.A O no hydrogen 3.369 N/A MET 187.A N PRO 183.A O no hydrogen 3.011 N/A GLY 188.A N PHE 184.A O no hydrogen 2.949 N/A VAL 189.A N HIS 185.A O no hydrogen 2.954 N/A ALA 190.A N MET 186.A O no hydrogen 2.978 N/A GLY 191.A N MET 187.A O no hydrogen 2.884 N/A VAL 192.A N GLY 188.A O no hydrogen 3.014 N/A LEU 193.A N VAL 189.A O no hydrogen 2.934 N/A GLY 194.A N ALA 190.A O no hydrogen 2.874 N/A GLY 195.A N GLY 191.A O no hydrogen 3.009 N/A ALA 196.A N VAL 192.A O no hydrogen 3.072 N/A LEU 197.A N LEU 193.A O no hydrogen 2.805 N/A LEU 198.A N GLY 194.A O no hydrogen 2.995 N/A CYS 199.A N GLY 195.A O no hydrogen 3.025 N/A ILE 201.A N LEU 197.A O no hydrogen 3.189 N/A HIS 202.A N LEU 198.A O no hydrogen 2.885 N/A GLY 203.A N CYS 199.A O no hydrogen 3.164 N/A ALA 204.A N ALA 200.A O no hydrogen 2.983 N/A THR 205.A N ILE 201.A O no hydrogen 2.941 N/A THR 205.A OG1 ILE 201.A O no hydrogen 2.827 N/A VAL 206.A N HIS 202.A O no hydrogen 3.048 N/A GLU 207.A N GLY 203.A O no hydrogen 3.005 N/A THR 209.A N VAL 206.A O no hydrogen 3.471 N/A THR 209.A OG1 THR 205.A O no hydrogen 2.909 N/A THR 231.A N GLU 230.A OE2 no hydrogen 3.228 N/A SER 233.A N THR 209.A O no hydrogen 3.371 N/A SER 233.A OG THR 236.A OG1 no hydrogen 3.116 N/A THR 236.A OG1 SER 233.A OG no hydrogen 3.116 N/A ALA 237.A N SER 233.A O no hydrogen 3.328 N/A ASN 238.A N MET 234.A O no hydrogen 3.004 N/A ASN 238.A ND2 PHE 249.A O no hydrogen 3.286 N/A ARG 239.A N VAL 235.A O no hydrogen 2.925 N/A ARG 239.A NE GLN 243.A OE1 no hydrogen 3.070 N/A PHE 240.A N THR 236.A O no hydrogen 2.931 N/A TRP 241.A N ALA 237.A O no hydrogen 2.999 N/A TRP 241.A NE1 THR 205.A OG1 no hydrogen 2.980 N/A SER 242.A N ASN 238.A O no hydrogen 2.946 N/A SER 242.A OG ASN 238.A O no hydrogen 2.806 N/A SER 242.A OG ARG 239.A O no hydrogen 3.151 N/A GLN 243.A N PHE 240.A O no hydrogen 3.204 N/A ILE 244.A N PHE 240.A O no hydrogen 3.140 N/A PHE 245.A N TRP 241.A O no hydrogen 3.268 N/A GLY 246.A N TRP 241.A O no hydrogen 3.320 N/A LYS 252.A NZ GLU 230.A OE1 no hydrogen 3.270 N/A LYS 252.A NZ GLU 230.A OE2 no hydrogen 3.086 N/A LEU 255.A N ASN 251.A O no hydrogen 3.081 N/A HIS 256.A N LYS 252.A O no hydrogen 3.017 N/A PHE 257.A N ARG 253.A O no hydrogen 3.144 N/A PHE 258.A N TRP 254.A O no hydrogen 2.898 N/A MET 259.A N LEU 255.A O no hydrogen 3.008 N/A LEU 260.A N HIS 256.A O no hydrogen 3.056 N/A PHE 261.A N PHE 257.A O no hydrogen 2.951 N/A PHE 261.A N PHE 258.A O no hydrogen 3.116 N/A VAL 262.A N PHE 258.A O no hydrogen 3.167 N/A THR 265.A N PHE 261.A O no hydrogen 3.234 N/A THR 265.A OG1 PHE 261.A O no hydrogen 2.849 N/A GLY 266.A N VAL 262.A O no hydrogen 3.083 N/A LEU 267.A N PRO 263.A O no hydrogen 2.996 N/A TRP 268.A N VAL 264.A O no hydrogen 2.951 N/A MET 269.A N THR 265.A O no hydrogen 2.876 N/A SER 270.A N GLY 266.A O no hydrogen 3.004 N/A SER 270.A OG GLY 266.A O no hydrogen 3.458 N/A SER 270.A OG LEU 267.A O no hydrogen 2.794 N/A ALA 271.A N LEU 267.A O no hydrogen 2.920 N/A ILE 272.A N TRP 268.A O no hydrogen 3.157 N/A GLY 273.A N MET 269.A O no hydrogen 3.062 N/A VAL 274.A N SER 270.A O no hydrogen 3.042 N/A VAL 275.A N ALA 271.A O no hydrogen 3.129 N/A GLY 276.A N ILE 272.A O no hydrogen 3.142 N/A LEU 277.A N VAL 274.A O no hydrogen 3.220 N/A ALA 278.A N VAL 275.A O no hydrogen 3.346 N/A ASN 280.A N LEU 277.A O no hydrogen 2.875 N/A LEU 281.A N GLY 276.A O no hydrogen 3.291 N/A ARG 282.A NH1 HIS 177.A ND1 no hydrogen 3.568 N/A SER 283.A OG LEU 181.A O no hydrogen 3.063 N/A PHE 286.A N TYR 303.A OH no hydrogen 3.182 N/A GLN 289.A N PHE 286.A O no hydrogen 3.037 N/A GLU 290.A N PHE 286.A O no hydrogen 3.454 N/A ILE 291.A N ILE 287.A O no hydrogen 3.062 N/A ARG 292.A N SER 288.A O no hydrogen 2.972 N/A ALA 293.A N GLN 289.A O no hydrogen 2.889 N/A ALA 294.A N GLU 290.A O no hydrogen 2.913 N/A GLU 295.A N ILE 291.A O no hydrogen 3.068 N/A ASP 296.A N ARG 292.A O no hydrogen 3.046 N/A THR 301.A N THR 304.A OG1 no hydrogen 3.313 N/A TYR 303.A OH GLU 290.A OE1 no hydrogen 2.908 N/A THR 304.A OG1 THR 301.A O no hydrogen 2.705 N/A ASN 306.A N PHE 302.A O no hydrogen 2.970 N/A LEU 307.A N TYR 303.A O no hydrogen 3.041 N/A LEU 308.A N THR 304.A O no hydrogen 3.029 N/A LEU 309.A N LYS 305.A O no hydrogen 2.936 N/A ASN 310.A N ASN 306.A O no hydrogen 2.850 N/A GLU 311.A N LEU 307.A O no hydrogen 2.999 N/A GLY 312.A N LEU 308.A O no hydrogen 3.047 N/A ILE 313.A N LEU 309.A O no hydrogen 2.951 N/A ARG 314.A N ASN 310.A O no hydrogen 3.010 N/A ARG 314.A NH1 TYR 284.A OH no hydrogen 2.825 N/A ARG 314.A NH2 TYR 284.A OH no hydrogen 3.304 N/A ARG 314.A NH2 GLU 311.A OE1 no hydrogen 3.235 N/A ALA 315.A N GLU 311.A O no hydrogen 2.975 N/A TRP 316.A N GLY 312.A O no hydrogen 3.122 N/A MET 317.A N ILE 313.A O no hydrogen 3.074 N/A MET 317.A N ARG 314.A O no hydrogen 3.361 N/A ALA 318.A N ARG 314.A O no hydrogen 2.988 N/A ASP 321.A N MET 317.A O no hydrogen 3.145 N/A ASP 321.A N ALA 318.A O no hydrogen 3.319 N/A GLN 322.A N ALA 318.A O no hydrogen 2.918 N/A GLU 325.A N GLN 322.A O no hydrogen 3.392 N/A ASN 326.A N PRO 323.A O no hydrogen 2.948 N/A GLU 331.A N GLU 331.A OE1 no hydrogen 2.308 N/A VAL 333.A N PRO 330.A O no hydrogen 3.507 N/A LEU 340.A N GLY 337.A O no hydrogen 3.223 N/A