Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7oic_s.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 18.A N SER 15.A OG no hydrogen 3.299 N/A ARG 19.A N SER 15.A O no hydrogen 2.984 N/A LEU 20.A N LYS 16.A O no hydrogen 2.931 N/A ARG 21.A N ALA 17.A O no hydrogen 2.963 N/A ARG 21.A NE ALA 9.A O no hydrogen 2.986 N/A ARG 21.A NH2 ALA 9.A O no hydrogen 3.154 N/A ARG 22.A N ALA 18.A O no hydrogen 2.963 N/A ARG 22.A NH1 MET 11.A O no hydrogen 2.461 N/A ARG 22.A NH1 ALA 13.A O no hydrogen 3.201 N/A ARG 22.A NH2 ALA 13.A O no hydrogen 3.432 N/A ILE 23.A N ARG 19.A O no hydrogen 2.949 N/A GLU 24.A N LEU 20.A O no hydrogen 2.920 N/A ARG 25.A N ARG 21.A O no hydrogen 2.953 N/A TRP 26.A N ARG 22.A O no hydrogen 3.012 N/A GLN 27.A N ILE 23.A O no hydrogen 2.918 N/A GLN 27.A NE2 GLN 322.A OE1 no hydrogen 3.037 N/A ALA 28.A N GLU 24.A O no hydrogen 2.880 N/A THR 29.A N ARG 25.A O no hydrogen 3.061 N/A THR 29.A OG1 TRP 26.A O no hydrogen 2.215 N/A VAL 30.A N TRP 26.A O no hydrogen 3.099 N/A HIS 31.A N GLN 27.A O no hydrogen 2.947 N/A ALA 32.A N ALA 28.A O no hydrogen 2.930 N/A ALA 33.A N THR 29.A O no hydrogen 3.001 N/A ALA 33.A N VAL 30.A O no hydrogen 3.124 N/A LYS 39.A N SER 35.A O no hydrogen 2.886 N/A LYS 39.A NZ GLY 284.A O no hydrogen 2.964 N/A LEU 40.A N VAL 36.A O no hydrogen 2.901 N/A ARG 41.A N ASP 37.A O no hydrogen 2.960 N/A ILE 42.A N GLU 38.A O no hydrogen 2.960 N/A LEU 43.A N LYS 39.A O no hydrogen 2.934 N/A THR 44.A N LEU 40.A O no hydrogen 2.927 N/A THR 44.A N ARG 41.A O no hydrogen 3.337 N/A THR 44.A OG1 LEU 40.A O no hydrogen 3.002 N/A THR 44.A OG1 ASN 220.A O no hydrogen 3.276 N/A LYS 50.A N ARG 216.A O no hydrogen 2.904 N/A LYS 50.A NZ GLN 172.A OE1 no hydrogen 2.330 N/A LYS 50.A NZ TYR 218.A O no hydrogen 3.465 N/A LYS 50.A NZ GLU 219.A O no hydrogen 2.947 N/A LYS 50.A NZ ASN 220.A OD1 no hydrogen 2.415 N/A TYR 51.A N ARG 170.A O no hydrogen 2.933 N/A MET 52.A N PHE 214.A O no hydrogen 2.947 N/A VAL 53.A N GLN 172.A O no hydrogen 2.912 N/A ALA 59.A N THR 57.A OG1 no hydrogen 3.167 N/A ARG 64.A N ASP 63.A OD1 no hydrogen 2.455 N/A TRP 65.A N ASN 61.A O no hydrogen 3.131 N/A TYR 66.A N ALA 62.A O no hydrogen 2.868 N/A TYR 66.A OH TYR 54.A O no hydrogen 2.523 N/A GLN 67.A N ASP 63.A O no hydrogen 2.920 N/A GLN 67.A NE2 ASP 63.A O no hydrogen 3.606 N/A TYR 68.A N ARG 64.A O no hydrogen 3.050 N/A PHE 69.A N TRP 65.A O no hydrogen 2.903 N/A THR 70.A OG1 TYR 66.A O no hydrogen 2.681 N/A LYS 71.A N GLN 67.A O no hydrogen 2.833 N/A THR 72.A N GLN 67.A O no hydrogen 3.361 N/A VAL 73.A N ASN 331.A O no hydrogen 2.866 N/A LEU 75.A N CYS 333.A O no hydrogen 2.849 N/A SER 76.A OG GLY 335.A O no hydrogen 3.413 N/A GLY 77.A N GLY 335.A O no hydrogen 2.573 N/A ALA 84.A N ALA 80.A O no hydrogen 2.939 N/A VAL 85.A N ALA 81.A O no hydrogen 2.906 N/A ALA 86.A N LEU 82.A O no hydrogen 2.909 N/A CYS 87.A N ARG 83.A O no hydrogen 2.977 N/A ASP 88.A N ALA 84.A O no hydrogen 2.859 N/A CYS 89.A N VAL 85.A O no hydrogen 2.930 N/A CYS 89.A SG PHE 116.A O no hydrogen 3.817 N/A LEU 90.A N ALA 86.A O no hydrogen 2.957 N/A LEU 91.A N CYS 87.A O no hydrogen 2.924 N/A GLN 92.A N ASP 88.A O no hydrogen 2.856 N/A GLU 93.A N CYS 89.A O no hydrogen 2.985 N/A HIS 94.A N LEU 90.A O no hydrogen 3.016 N/A HIS 94.A ND1 LEU 90.A O no hydrogen 3.132 N/A PHE 95.A N LEU 91.A O no hydrogen 2.881 N/A TYR 96.A N LEU 91.A O no hydrogen 2.898 N/A LEU 97.A N GLN 92.A O no hydrogen 3.166 N/A HIS 104.A N GLU 107.A OE2 no hydrogen 3.023 N/A GLU 107.A N HIS 104.A O no hydrogen 3.291 N/A SER 109.A N ASP 244.A OD2 no hydrogen 3.398 N/A ILE 112.A N GLU 108.A O no hydrogen 2.847 N/A SER 113.A N SER 109.A O no hydrogen 2.952 N/A LEU 114.A N SER 109.A O no hydrogen 3.308 N/A PHE 116.A N ILE 112.A O no hydrogen 3.229 N/A LEU 117.A N SER 113.A O no hydrogen 3.050 N/A ASP 118.A N LEU 114.A O no hydrogen 2.985 N/A GLN 119.A N PRO 115.A O no hydrogen 2.955 N/A LEU 120.A N PHE 116.A O no hydrogen 2.883 N/A VAL 121.A N LEU 117.A O no hydrogen 2.886 N/A SER 122.A N ASP 118.A O no hydrogen 3.021 N/A THR 123.A N GLN 119.A O no hydrogen 2.898 N/A THR 123.A OG1 GLN 119.A O no hydrogen 2.978 N/A THR 123.A OG1 LEU 120.A O no hydrogen 3.173 N/A LEU 124.A N LEU 120.A O no hydrogen 2.906 N/A VAL 125.A N VAL 121.A O no hydrogen 2.914 N/A GLY 126.A N SER 122.A O no hydrogen 2.950 N/A LEU 127.A N THR 123.A O no hydrogen 2.880 N/A LEU 128.A N LEU 124.A O no hydrogen 2.900 N/A LEU 128.A N VAL 125.A O no hydrogen 3.334 N/A SER 129.A N VAL 125.A O no hydrogen 2.937 N/A SER 129.A OG GLY 126.A O no hydrogen 3.067 N/A ASN 132.A N LEU 128.A O no hydrogen 2.964 N/A ASN 132.A ND2 ASN 367.A O no hydrogen 3.066 N/A ALA 134.A N ASN 132.A OD1 no hydrogen 3.258 N/A ALA 139.A N ARG 182.A O no hydrogen 2.882 N/A ASP 141.A N GLN 180.A O no hydrogen 2.912 N/A ARG 143.A N ASN 178.A O no hydrogen 2.597 N/A ARG 143.A NH1 ASP 118.A OD2 no hydrogen 3.381 N/A ARG 143.A NH2 ASP 118.A OD2 no hydrogen 2.979 N/A VAL 146.A N ASP 175.A O no hydrogen 2.857 N/A PHE 148.A N ILE 173.A O no hydrogen 3.224 N/A TRP 150.A N TYR 171.A O no hydrogen 3.162 N/A TRP 150.A NE1 PHE 69.A O no hydrogen 2.701 N/A ARG 152.A N LEU 169.A O no hydrogen 3.218 N/A ARG 152.A NE TYR 68.A O no hydrogen 3.090 N/A ARG 152.A NH1 TYR 68.A O no hydrogen 3.123 N/A ARG 152.A NH2 LEU 319.A O no hydrogen 3.402 N/A ARG 152.A NH2 ASP 324.A OD1 no hydrogen 3.497 N/A GLU 155.A N ASP 167.A O no hydrogen 2.893 N/A ILE 157.A N ARG 165.A O no hydrogen 3.021 N/A ARG 163.A N GLY 160.A O no hydrogen 3.322 N/A GLY 164.A N ILE 157.A O no hydrogen 2.973 N/A ASP 167.A N GLU 155.A O no hydrogen 2.983 N/A LEU 169.A N GLY 153.A O no hydrogen 2.973 N/A ARG 170.A NH1 ASP 167.A OD1 no hydrogen 2.997 N/A ARG 170.A NH2 ASP 167.A OD1 no hydrogen 2.606 N/A TYR 171.A N TRP 150.A O no hydrogen 2.868 N/A GLN 172.A N TYR 51.A O no hydrogen 2.919 N/A ILE 173.A N PHE 148.A O no hydrogen 3.121 N/A LYS 176.A NZ ARG 143.A O no hydrogen 3.534 N/A ASN 179.A N PHE 239.A O no hydrogen 3.086 N/A ASN 179.A ND2 LEU 117.A O no hydrogen 3.657 N/A GLN 180.A N ASP 141.A O no hydrogen 2.918 N/A GLN 180.A NE2 ASP 141.A OD2 no hydrogen 3.257 N/A ILE 181.A N THR 237.A O no hydrogen 2.774 N/A ARG 182.A N ALA 139.A O no hydrogen 2.902 N/A ARG 182.A NE ASP 141.A OD2 no hydrogen 2.582 N/A ARG 182.A NH1 ASP 141.A OD1 no hydrogen 2.691 N/A ARG 182.A NH1 ASP 141.A OD2 no hydrogen 2.953 N/A ARG 182.A NH2 ASP 230.A OD2 no hydrogen 3.111 N/A ILE 183.A N TYR 234.A O no hydrogen 2.835 N/A ILE 199.A N VAL 197.A O no hydrogen 2.846 N/A LYS 210.A N LYS 207.A O no hydrogen 3.264 N/A ARG 216.A N LYS 50.A O no hydrogen 2.888 N/A TYR 218.A OH ASP 174.A OD2 no hydrogen 3.041 N/A PHE 223.A N HIS 147.A O no hydrogen 2.647 N/A THR 228.A OG1 ASP 37.A OD1 no hydrogen 2.359 N/A CYS 232.A SG ALA 137.A O no hydrogen 3.344 N/A CYS 233.A N PRO 231.A O no hydrogen 2.864 N/A CYS 233.A SG PRO 231.A O no hydrogen 3.823 N/A CYS 233.A SG GLN 283.A OE1 no hydrogen 3.239 N/A HIS 236.A N ILE 181.A O no hydrogen 2.924 N/A THR 237.A N ILE 181.A O no hydrogen 3.149 N/A THR 237.A OG1 PHE 364.A O no hydrogen 3.391 N/A GLN 238.A N GLN 298.A O no hydrogen 2.877 N/A PHE 239.A N ASN 179.A O no hydrogen 2.838 N/A HIS 240.A N VAL 300.A O no hydrogen 2.975 N/A LEU 242.A N THR 302.A O no hydrogen 2.855 N/A LEU 246.A N PRO 243.A O no hydrogen 3.175 N/A ARG 247.A NE ASP 244.A O no hydrogen 2.625 N/A GLU 249.A N GLU 249.A OE2 no hydrogen 2.797 N/A LEU 251.A N ARG 247.A O no hydrogen 2.912 N/A LEU 252.A N ARG 248.A O no hydrogen 2.907 N/A ARG 253.A N GLU 249.A O no hydrogen 2.890 N/A GLN 254.A N ARG 250.A O no hydrogen 2.803 N/A CYS 256.A SG LEU 251.A O no hydrogen 3.238 N/A VAL 262.A N ASP 258.A O no hydrogen 2.957 N/A VAL 263.A N GLN 259.A O no hydrogen 2.948 N/A PHE 264.A N ILE 260.A O no hydrogen 3.080 N/A ARG 265.A N GLU 261.A O no hydrogen 2.921 N/A ARG 265.A NE GLU 261.A O no hydrogen 3.358 N/A ALA 266.A N VAL 262.A O no hydrogen 2.889 N/A ASN 267.A N VAL 263.A O no hydrogen 3.063 N/A ALA 268.A N PHE 264.A O no hydrogen 3.015 N/A ILE 269.A N ARG 265.A O no hydrogen 2.902 N/A ALA 270.A N ALA 266.A O no hydrogen 3.044 N/A SER 271.A N ASN 267.A O no hydrogen 2.970 N/A SER 271.A OG ASP 175.A OD2 no hydrogen 2.337 N/A SER 271.A OG HIS 240.A NE2 no hydrogen 3.155 N/A SER 271.A OG ASN 267.A O no hydrogen 3.149 N/A SER 271.A OG ASN 267.A OD1 no hydrogen 2.938 N/A LEU 272.A N ALA 268.A O no hydrogen 2.946 N/A PHE 273.A N ILE 269.A O no hydrogen 2.952 N/A ALA 274.A N ALA 270.A O no hydrogen 2.999 N/A TRP 275.A N SER 271.A O no hydrogen 3.003 N/A THR 276.A N LEU 272.A O no hydrogen 2.932 N/A THR 276.A OG1 LEU 272.A O no hydrogen 2.921 N/A THR 276.A OG1 PHE 273.A O no hydrogen 3.360 N/A GLY 277.A N PHE 273.A O no hydrogen 2.861 N/A ALA 278.A N ALA 274.A O no hydrogen 2.891 N/A GLN 279.A N TRP 275.A O no hydrogen 2.996 N/A GLN 279.A NE2 GLY 235.A O no hydrogen 3.617 N/A GLN 279.A NE2 SER 297.A OG no hydrogen 3.126 N/A ALA 280.A N THR 276.A O no hydrogen 2.962 N/A MET 281.A N GLY 277.A O no hydrogen 2.937 N/A TYR 282.A N ALA 278.A O no hydrogen 2.961 N/A TYR 282.A OH SER 226.A O no hydrogen 3.316 N/A GLN 283.A N GLN 279.A O no hydrogen 2.943 N/A GLY 284.A N ALA 280.A O no hydrogen 3.005 N/A GLY 284.A N MET 281.A O no hydrogen 3.331 N/A TRP 286.A N ALA 289.A O no hydrogen 2.954 N/A VAL 291.A N ASP 290.A OD1 no hydrogen 2.897 N/A PHE 295.A N LEU 314.A O no hydrogen 2.974 N/A SER 297.A N TYR 312.A O no hydrogen 2.969 N/A SER 297.A OG GLY 235.A O no hydrogen 3.274 N/A SER 297.A OG VAL 296.A O no hydrogen 2.539 N/A GLN 298.A NE2 HIS 236.A O no hydrogen 3.616 N/A GLN 298.A NE2 PHE 364.A O no hydrogen 3.188 N/A ALA 299.A N PHE 310.A O no hydrogen 2.921 N/A VAL 300.A N GLN 238.A O no hydrogen 2.937 N/A ILE 301.A N SER 308.A O no hydrogen 2.950 N/A THR 302.A N HIS 240.A O no hydrogen 2.924 N/A THR 302.A OG1 TYR 306.A O no hydrogen 2.531 N/A ASP 303.A N TYR 306.A O no hydrogen 2.954 N/A GLY 304.A N THR 302.A OG1 no hydrogen 3.121 N/A LYS 305.A N ASP 303.A OD1 no hydrogen 3.356 N/A LYS 305.A NZ GLU 343.A O no hydrogen 3.142 N/A TYR 306.A N ASP 303.A OD1 no hydrogen 2.628 N/A PHE 307.A N LYS 339.A O no hydrogen 2.894 N/A SER 308.A N ILE 301.A O no hydrogen 2.920 N/A PHE 309.A N THR 336.A OG1 no hydrogen 2.749 N/A PHE 310.A N ALA 299.A O no hydrogen 2.848 N/A CYS 311.A N TRP 334.A O no hydrogen 2.948 N/A TYR 312.A N SER 297.A O no hydrogen 2.886 N/A GLN 313.A N ILE 332.A O no hydrogen 2.953 N/A GLN 313.A NE2 VAL 191.A O no hydrogen 3.003 N/A LEU 314.A N PHE 295.A O no hydrogen 2.782 N/A ASN 315.A N ASN 331.A OD1 no hydrogen 3.018 N/A ASN 315.A ND2 LYS 330.A O no hydrogen 2.963 N/A THR 316.A N ASN 331.A OD1 no hydrogen 2.850 N/A THR 316.A OG1 ASN 331.A OD1 no hydrogen 2.831 N/A LEU 317.A N ASP 290.A OD1 no hydrogen 2.585 N/A ASP 324.A N THR 321.A O no hydrogen 3.257 N/A GLN 325.A N THR 321.A O no hydrogen 3.021 N/A GLN 325.A NE2 GLN 322.A O no hydrogen 3.276 N/A ASN 327.A ND2 ALA 318.A O no hydrogen 3.307 N/A ARG 329.A NH1 VAL 291.A O no hydrogen 3.232 N/A ARG 329.A NH2 VAL 291.A O no hydrogen 2.875 N/A ARG 329.A NH2 ASN 315.A O no hydrogen 2.741 N/A ASN 331.A N LYS 71.A O no hydrogen 2.839 N/A ILE 332.A N GLN 313.A O no hydrogen 3.008 N/A CYS 333.A N VAL 73.A O no hydrogen 2.966 N/A CYS 333.A SG CYS 311.A O no hydrogen 4.006 N/A TRP 334.A N CYS 311.A O no hydrogen 2.820 N/A GLY 335.A N LEU 75.A O no hydrogen 2.926 N/A THR 336.A N PHE 309.A O no hydrogen 3.068 N/A THR 336.A OG1 PHE 309.A O no hydrogen 2.624 N/A GLN 337.A NE2 GLU 261.A OE1 no hydrogen 2.587 N/A SER 338.A N GLU 261.A OE2 no hydrogen 3.439 N/A SER 338.A OG GLU 261.A OE2 no hydrogen 3.501 N/A LYS 339.A N PHE 307.A O no hydrogen 2.883 N/A LEU 341.A N LYS 305.A O no hydrogen 2.895 N/A GLU 346.A N ASP 349.A O no hydrogen 3.401 N/A ASN 348.A N GLU 346.A O no hydrogen 2.730 N/A ASN 348.A ND2 GLU 346.A O no hydrogen 3.349 N/A LYS 351.A N THR 344.A O no hydrogen 3.446 N/A LYS 351.A NZ ASP 349.A OD2 no hydrogen 2.914 N/A ASN 354.A ND2 PRO 340.A O no hydrogen 3.121 N/A ASP 356.A N ASN 354.A OD1 no hydrogen 3.086 N/A LEU 358.A N ASN 354.A O no hydrogen 3.151 N/A LEU 359.A N ASP 355.A O no hydrogen 2.879 N/A GLN 360.A N ASP 356.A O no hydrogen 2.955 N/A ILE 361.A N VAL 357.A O no hydrogen 3.073 N/A VAL 362.A N LEU 358.A O no hydrogen 3.012 N/A HIS 363.A N LEU 359.A O no hydrogen 2.850 N/A PHE 364.A N GLN 360.A O no hydrogen 2.992 N/A LEU 365.A N ILE 361.A O no hydrogen 2.988 N/A LEU 366.A N HIS 363.A O no hydrogen 2.783 N/A ASN 367.A N HIS 363.A O no hydrogen 3.047 N/A ASN 367.A ND2 GLN 298.A OE1 no hydrogen 2.739 N/A