Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7p6n_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A N ALA 1.A O no hydrogen 2.868 N/A ARG 5.A NE ALA 1.A O no hydrogen 3.183 N/A LEU 7.A N ARG 3.A O no hydrogen 3.068 N/A GLU 8.A N GLN 4.A O no hydrogen 3.406 N/A ALA 9.A N ARG 5.A O no hydrogen 2.911 N/A LEU 10.A N LYS 6.A O no hydrogen 3.307 N/A ILE 11.A N LEU 7.A O no hydrogen 3.306 N/A ARG 12.A N GLU 8.A O no hydrogen 3.260 N/A ARG 12.A N ALA 9.A O no hydrogen 3.040 N/A ASP 13.A N ALA 9.A O no hydrogen 3.012 N/A ARG 15.A N ASP 13.A OD1 no hydrogen 3.267 N/A SER 16.A N ASP 13.A O no hydrogen 3.037 N/A SER 16.A OG LEU 10.A O no hydrogen 2.709 N/A ILE 18.A N SER 16.A OG no hydrogen 3.178 N/A ASN 19.A N SER 16.A O no hydrogen 3.135 N/A SER 22.A N ASN 19.A OD1 no hydrogen 2.998 N/A SER 22.A OG PRO 17.A O no hydrogen 3.123 N/A SER 22.A OG ASN 19.A OD1 no hydrogen 2.623 N/A LEU 23.A N ASN 19.A O no hydrogen 3.129 N/A LEU 24.A N VAL 20.A O no hydrogen 3.147 N/A ASP 25.A N GLU 21.A O no hydrogen 2.967 N/A GLY 26.A N SER 22.A O no hydrogen 2.994 N/A LEU 27.A N LEU 23.A O no hydrogen 3.061 N/A ASN 28.A N LEU 24.A O no hydrogen 2.954 N/A ASN 28.A ND2 GLN 63.A OE1 no hydrogen 3.528 N/A SER 29.A N ASP 25.A O no hydrogen 2.665 N/A SER 29.A OG ASP 25.A O no hydrogen 3.068 N/A LEU 30.A N GLY 26.A O no hydrogen 3.321 N/A VAL 31.A N LEU 27.A O no hydrogen 3.104 N/A LEU 32.A N ASN 28.A O no hydrogen 2.980 N/A ASP 33.A N SER 29.A O no hydrogen 3.164 N/A LEU 34.A N LEU 30.A O no hydrogen 3.176 N/A LEU 34.A N VAL 31.A O no hydrogen 3.171 N/A ASP 35.A N VAL 31.A O no hydrogen 2.776 N/A PHE 36.A N LEU 34.A O no hydrogen 2.689 N/A LEU 39.A N PHE 36.A O no hydrogen 2.953 N/A ARG 40.A N PHE 36.A O no hydrogen 3.292 N/A ARG 40.A NE ASP 35.A OD1 no hydrogen 3.239 N/A ARG 40.A NH1 ASP 46.A OD1 no hydrogen 2.584 N/A ARG 40.A NH1 ASN 50.A OD1 no hydrogen 3.043 N/A ASN 42.A N LEU 39.A O no hydrogen 3.018 N/A ASP 46.A N ASN 42.A O no hydrogen 3.191 N/A ASN 47.A N LYS 43.A O no hydrogen 2.863 N/A PHE 48.A N ASN 44.A O no hydrogen 3.238 N/A LEU 49.A N ILE 45.A O no hydrogen 2.781 N/A ASN 50.A N ASP 46.A O no hydrogen 2.894 N/A ARG 51.A N ASN 47.A O no hydrogen 3.022 N/A TYR 52.A N PHE 48.A O no hydrogen 3.044 N/A GLU 53.A N LEU 49.A O no hydrogen 2.633 N/A VAL 56.A N TYR 52.A O no hydrogen 2.870 N/A LYS 57.A N GLU 53.A O no hydrogen 3.198 N/A LYS 58.A N LYS 54.A O no hydrogen 3.220 N/A ILE 59.A N ILE 55.A O no hydrogen 3.000 N/A ARG 60.A N VAL 56.A O no hydrogen 3.120 N/A LEU 62.A N LYS 58.A O no hydrogen 3.238 N/A GLN 63.A N ILE 59.A O no hydrogen 2.796 N/A MET 64.A N TYR 383.A OH no hydrogen 3.028 N/A LYS 65.A N ASP 68.A OD2 no hydrogen 3.073 N/A LYS 65.A NZ ASP 68.A OD1 no hydrogen 3.443 N/A GLU 67.A N GLU 67.A OE1 no hydrogen 2.712 N/A ASP 68.A N LYS 65.A O no hydrogen 2.961 N/A TYR 69.A N ALA 66.A O no hydrogen 3.114 N/A ASP 70.A N ARG 87.A O no hydrogen 2.821 N/A VAL 72.A N LEU 85.A O no hydrogen 2.854 N/A ILE 75.A N VAL 83.A O no hydrogen 2.915 N/A GLY 78.A N GLY 81.A O no hydrogen 2.980 N/A GLY 81.A N GLY 78.A O no hydrogen 3.268 N/A VAL 83.A N GLY 76.A O no hydrogen 3.082 N/A GLN 84.A N MET 97.A O no hydrogen 2.792 N/A GLN 84.A NE2 GLU 82.A OE1 no hydrogen 3.056 N/A LEU 85.A N LYS 73.A O no hydrogen 2.908 N/A VAL 86.A N TYR 95.A O no hydrogen 2.989 N/A ARG 87.A N ASP 70.A O no hydrogen 2.903 N/A ARG 87.A NH1 GLN 92.A O no hydrogen 3.477 N/A ARG 87.A NH1 ASP 349.A OD2 no hydrogen 3.236 N/A HIS 88.A N LYS 93.A O no hydrogen 2.857 N/A LYS 89.A N ASP 68.A O no hydrogen 2.903 N/A LYS 89.A NZ GLU 67.A O no hydrogen 2.824 N/A GLN 92.A N HIS 88.A O no hydrogen 2.704 N/A TYR 95.A N VAL 86.A O no hydrogen 2.907 N/A ALA 96.A N MET 146.A O no hydrogen 2.937 N/A MET 97.A N GLN 84.A O no hydrogen 2.785 N/A LYS 98.A N MET 144.A O no hydrogen 2.968 N/A LYS 98.A NZ GLU 117.A OE1 no hydrogen 2.913 N/A LYS 98.A NZ GLU 117.A OE2 no hydrogen 2.860 N/A LEU 99.A N GLU 82.A O no hydrogen 2.837 N/A LEU 100.A N LEU 142.A O no hydrogen 2.969 N/A SER 101.A N PHE 80.A O no hydrogen 2.926 N/A LYS 102.A N ARG 140.A O no hydrogen 2.894 N/A LYS 102.A NZ GLN 137.A OE1 no hydrogen 2.943 N/A LYS 102.A NZ ASP 138.A O no hydrogen 2.613 N/A LYS 102.A NZ GLN 374.A OE1 no hydrogen 3.010 N/A GLU 104.A N SER 101.A OG no hydrogen 3.086 N/A MET 105.A N SER 101.A O no hydrogen 3.354 N/A ILE 106.A N LYS 102.A O no hydrogen 3.105 N/A LYS 107.A N PHE 103.A O no hydrogen 2.879 N/A ARG 108.A N GLU 104.A O no hydrogen 2.837 N/A ARG 108.A NE GLU 104.A OE1 no hydrogen 3.030 N/A ARG 108.A NH2 ALA 79.A O no hydrogen 3.538 N/A ARG 108.A NH2 GLU 104.A OE1 no hydrogen 2.859 N/A ASP 110.A N ARG 108.A O no hydrogen 2.459 N/A TRP 115.A N ALA 112.A O no hydrogen 3.140 N/A GLU 117.A N PHE 113.A O no hydrogen 3.393 N/A ARG 118.A N PHE 114.A O no hydrogen 2.895 N/A ARG 118.A NE ASP 119.A OD1 no hydrogen 3.269 N/A ARG 118.A NH1 PHE 380.A O no hydrogen 2.644 N/A ARG 118.A NH2 ASP 119.A OD1 no hydrogen 2.961 N/A ASP 119.A N TRP 115.A O no hydrogen 2.949 N/A ILE 120.A N GLU 116.A O no hydrogen 2.779 N/A MET 121.A N GLU 117.A O no hydrogen 3.144 N/A ALA 122.A N ARG 118.A O no hydrogen 2.739 N/A PHE 123.A N ASP 119.A O no hydrogen 2.916 N/A ALA 124.A N ILE 120.A O no hydrogen 3.054 N/A TRP 128.A N SER 126.A OG no hydrogen 3.339 N/A VAL 129.A N SER 126.A O no hydrogen 3.374 N/A VAL 130.A N LEU 207.A O no hydrogen 3.179 N/A GLN 131.A N GLU 147.A OE2 no hydrogen 3.089 N/A LEU 132.A N MET 121.A O no hydrogen 2.825 N/A PHE 133.A N VAL 145.A O no hydrogen 2.866 N/A TYR 134.A N VAL 145.A O no hydrogen 3.493 N/A ALA 135.A N TYR 382.A O no hydrogen 2.860 N/A PHE 136.A N TYR 143.A O no hydrogen 3.316 N/A GLN 137.A NE2 PHE 377.A O no hydrogen 2.737 N/A ASP 138.A N TYR 141.A O no hydrogen 3.120 N/A LEU 142.A N LEU 100.A O no hydrogen 2.975 N/A TYR 143.A N PHE 136.A O no hydrogen 2.996 N/A TYR 143.A OH ASP 138.A OD2 no hydrogen 2.645 N/A MET 144.A N LYS 98.A O no hydrogen 2.940 N/A VAL 145.A N TYR 134.A O no hydrogen 2.766 N/A MET 146.A N ALA 96.A O no hydrogen 2.715 N/A GLU 147.A N GLN 131.A O no hydrogen 3.228 N/A TYR 148.A OH ASP 351.A O no hydrogen 2.730 N/A GLY 151.A N LEU 199.A O no hydrogen 2.967 N/A GLY 152.A N MET 149.A O no hydrogen 3.410 N/A LEU 154.A N PRO 194.A O no hydrogen 3.298 N/A LEU 154.A N MET 197.A O no hydrogen 3.242 N/A LEU 157.A N ASP 153.A O no hydrogen 3.199 N/A MET 158.A N LEU 154.A O no hydrogen 2.862 N/A SER 159.A N VAL 155.A O no hydrogen 2.848 N/A SER 159.A OG ASN 156.A O no hydrogen 3.173 N/A SER 159.A OG ASN 160.A OD1 no hydrogen 3.006 N/A ASN 160.A N LEU 157.A O no hydrogen 3.129 N/A ALA 168.A N PRO 164.A O no hydrogen 3.145 N/A LYS 169.A N GLU 165.A O no hydrogen 2.889 N/A LYS 169.A NZ LYS 326.A O no hydrogen 3.518 N/A PHE 170.A N LYS 166.A O no hydrogen 3.316 N/A TYR 171.A N TRP 167.A O no hydrogen 2.975 N/A THR 172.A N ALA 168.A O no hydrogen 2.844 N/A THR 172.A OG1 ALA 168.A O no hydrogen 2.699 N/A ALA 173.A N LYS 169.A O no hydrogen 3.004 N/A GLU 174.A N PHE 170.A O no hydrogen 2.965 N/A VAL 175.A N TYR 171.A O no hydrogen 3.055 N/A VAL 176.A N THR 172.A O no hydrogen 2.820 N/A LEU 177.A N ALA 173.A O no hydrogen 3.181 N/A ALA 178.A N GLU 174.A O no hydrogen 3.026 N/A LEU 179.A N VAL 175.A O no hydrogen 2.888 N/A ASP 180.A N VAL 176.A O no hydrogen 3.012 N/A ALA 181.A N LEU 177.A O no hydrogen 3.059 N/A ILE 182.A N ALA 178.A O no hydrogen 3.098 N/A HIS 183.A N LEU 179.A O no hydrogen 2.664 N/A HIS 183.A NE2 ASP 247.A OD2 no hydrogen 2.798 N/A SER 184.A N ASP 180.A O no hydrogen 2.707 N/A SER 184.A OG ASP 180.A O no hydrogen 2.724 N/A MET 185.A N ALA 181.A O no hydrogen 2.985 N/A GLY 186.A N HIS 183.A O no hydrogen 2.695 N/A LEU 187.A N ILE 182.A O no hydrogen 3.138 N/A ILE 188.A N MET 214.A O no hydrogen 3.191 N/A HIS 189.A N ASP 247.A OD2 no hydrogen 3.053 N/A ARG 190.A N ASP 247.A OD1 no hydrogen 2.766 N/A ARG 190.A NE TYR 242.A OH no hydrogen 3.471 N/A ARG 190.A NH1 THR 212.A O no hydrogen 3.047 N/A ARG 190.A NH2 TYR 242.A OH no hydrogen 3.276 N/A VAL 192.A N ARG 190.A O no hydrogen 2.952 N/A LYS 193.A NZ ASP 191.A OD2 no hydrogen 3.495 N/A ASN 196.A N LYS 193.A O no hydrogen 3.062 N/A ASN 196.A ND2 ASP 191.A O no hydrogen 2.781 N/A ASN 196.A ND2 ASP 191.A OD2 no hydrogen 3.388 N/A LEU 198.A N LYS 206.A O no hydrogen 2.832 N/A ASP 200.A N HIS 204.A O no hydrogen 2.868 N/A HIS 202.A N ASP 200.A OD1 no hydrogen 3.013 N/A GLY 203.A N ASP 200.A O no hydrogen 2.863 N/A HIS 204.A N ASP 200.A OD1 no hydrogen 2.881 N/A HIS 204.A ND1 GLU 174.A OE2 no hydrogen 2.744 N/A HIS 204.A NE2 THR 338.A O no hydrogen 2.687 N/A LEU 205.A N GLU 174.A OE1 no hydrogen 2.705 N/A LYS 206.A N LEU 198.A O no hydrogen 2.810 N/A LYS 206.A NZ GLU 147.A OE1 no hydrogen 3.439 N/A LYS 206.A NZ GLU 147.A OE2 no hydrogen 2.989 N/A LEU 207.A N TRP 128.A O no hydrogen 2.731 N/A ALA 208.A N ASN 196.A O no hydrogen 3.437 N/A GLY 211.A N ASP 209.A OD1 no hydrogen 3.141 N/A THR 212.A OG1 HIS 189.A O no hydrogen 2.712 N/A CYS 213.A N PHE 210.A O no hydrogen 2.908 N/A MET 214.A N ILE 188.A O no hydrogen 3.213 N/A LYS 215.A NZ MET 185.A O no hydrogen 3.421 N/A MET 216.A N GLY 186.A O no hydrogen 3.065 N/A ASP 217.A N MET 221.A O no hydrogen 2.962 N/A GLU 218.A N GLU 218.A OE1 no hydrogen 3.102 N/A THR 219.A OG1 ASP 217.A OD1 no hydrogen 2.621 N/A GLY 220.A N ASP 217.A OD1 no hydrogen 2.997 N/A MET 221.A N ASP 217.A OD1 no hydrogen 3.130 N/A VAL 222.A N TYR 242.A O no hydrogen 3.141 N/A TYR 230.A OH GLU 257.A OE1 no hydrogen 2.555 N/A ILE 231.A N PRO 228.A O no hydrogen 3.172 N/A GLU 234.A N GLU 234.A OE1 no hydrogen 2.893 N/A LEU 236.A N PRO 233.A O no hydrogen 2.953 N/A LYS 237.A N GLU 234.A O no hydrogen 3.185 N/A SER 238.A N GLU 234.A O no hydrogen 3.324 N/A SER 238.A OG GLU 234.A O no hydrogen 3.347 N/A SER 238.A OG VAL 235.A O no hydrogen 2.769 N/A GLN 239.A N VAL 235.A O no hydrogen 3.297 N/A TYR 242.A N VAL 222.A O no hydrogen 3.260 N/A CYS 246.A N GLY 243.A O no hydrogen 3.409 N/A CYS 246.A SG GLY 243.A O no hydrogen 3.279 N/A ASP 247.A N ARG 244.A O no hydrogen 2.946 N/A TRP 249.A N GLU 245.A O no hydrogen 3.185 N/A SER 250.A OG TYR 230.A O no hydrogen 2.806 N/A SER 250.A OG CYS 246.A O no hydrogen 3.218 N/A VAL 251.A N ASP 247.A O no hydrogen 3.223 N/A VAL 251.A N TRP 248.A O no hydrogen 3.195 N/A GLY 252.A N TRP 248.A O no hydrogen 3.253 N/A VAL 253.A N TRP 249.A O no hydrogen 3.083 N/A PHE 254.A N SER 250.A O no hydrogen 3.075 N/A LEU 255.A N VAL 251.A O no hydrogen 2.957 N/A TYR 256.A N GLY 252.A O no hydrogen 3.014 N/A TYR 256.A OH CYS 285.A O no hydrogen 3.242 N/A GLU 257.A N VAL 253.A O no hydrogen 2.993 N/A MET 258.A N PHE 254.A O no hydrogen 3.016 N/A LEU 259.A N LEU 255.A O no hydrogen 3.028 N/A VAL 260.A N TYR 256.A O no hydrogen 2.760 N/A THR 263.A OG1 ASP 229.A OD2 no hydrogen 2.779 N/A TYR 266.A N THR 263.A O no hydrogen 3.398 N/A GLY 272.A N SER 269.A OG no hydrogen 2.791 N/A THR 273.A OG1 PHE 265.A O no hydrogen 3.527 N/A THR 273.A OG1 SER 269.A O no hydrogen 3.311 N/A TYR 274.A N LEU 270.A O no hydrogen 2.948 N/A SER 275.A N VAL 271.A O no hydrogen 2.990 N/A LYS 276.A N GLY 272.A O no hydrogen 2.936 N/A ILE 277.A N THR 273.A O no hydrogen 2.917 N/A MET 278.A N TYR 274.A O no hydrogen 3.044 N/A ASP 279.A N SER 275.A O no hydrogen 3.100 N/A HIS 280.A N ILE 277.A O no hydrogen 3.061 N/A HIS 280.A NE2 ASP 306.A OD1 no hydrogen 2.892 N/A LYS 281.A NZ ASP 306.A OD2 no hydrogen 3.259 N/A ASN 282.A N ASP 279.A O no hydrogen 2.727 N/A ASN 282.A ND2 ASP 279.A OD1 no hydrogen 2.968 N/A SER 283.A N ASP 279.A O no hydrogen 2.967 N/A SER 283.A OG LYS 276.A O no hydrogen 2.584 N/A LEU 284.A N HIS 280.A O no hydrogen 3.216 N/A ALA 290.A N PRO 287.A O no hydrogen 3.110 N/A SER 293.A N GLU 165.A OE2 no hydrogen 2.947 N/A SER 293.A OG GLU 165.A OE1 no hydrogen 2.873 N/A SER 293.A OG GLU 165.A OE2 no hydrogen 3.478 N/A ALA 296.A N SER 293.A OG no hydrogen 2.987 N/A LYS 297.A N SER 293.A O no hydrogen 2.923 N/A ASN 298.A N LYS 294.A O no hydrogen 2.714 N/A LEU 299.A N HIS 295.A O no hydrogen 2.898 N/A ILE 300.A N ALA 296.A O no hydrogen 3.186 N/A CYS 301.A N LYS 297.A O no hydrogen 3.111 N/A CYS 301.A SG LYS 297.A O no hydrogen 3.385 N/A ALA 302.A N ASN 298.A O no hydrogen 2.892 N/A PHE 303.A N LEU 299.A O no hydrogen 3.163 N/A LEU 304.A N ILE 300.A O no hydrogen 2.921 N/A THR 305.A OG1 ASP 306.A O no hydrogen 2.891 N/A ARG 307.A NH1 PHE 241.A O no hydrogen 3.236 N/A VAL 309.A N ASP 306.A O no hydrogen 3.254 N/A ARG 310.A N ARG 307.A O no hydrogen 3.359 N/A ARG 310.A NE THR 305.A O no hydrogen 3.195 N/A ARG 310.A NH1 GLU 234.A OE1 no hydrogen 3.325 N/A ARG 310.A NH1 GLU 234.A OE2 no hydrogen 2.744 N/A ARG 310.A NH1 GLU 245.A O no hydrogen 3.314 N/A ARG 310.A NH2 GLU 234.A OE1 no hydrogen 2.962 N/A ARG 310.A NH2 THR 305.A O no hydrogen 3.018 N/A LEU 311.A N ALA 302.A O no hydrogen 3.201 N/A GLY 312.A N GLU 318.A OE2 no hydrogen 3.218 N/A ARG 320.A N VAL 316.A O no hydrogen 3.223 N/A GLN 321.A N GLU 317.A O no hydrogen 3.160 N/A HIS 322.A N ILE 319.A O no hydrogen 3.125 N/A PHE 325.A N HIS 322.A O no hydrogen 3.237 N/A LYS 326.A N PRO 323.A O no hydrogen 2.822 N/A LYS 326.A NZ GLN 321.A O no hydrogen 2.926 N/A TRP 330.A N ASN 327.A OD1 no hydrogen 3.506 N/A HIS 331.A N ASN 334.A OD1 no hydrogen 2.989 N/A ASN 334.A N HIS 331.A O no hydrogen 3.302 N/A ARG 336.A NE LEU 205.A O no hydrogen 3.317 N/A ARG 336.A NH2 ASP 200.A OD2 no hydrogen 2.726 N/A ARG 336.A NH2 LEU 205.A O no hydrogen 3.062 N/A GLU 337.A N ASN 334.A O no hydrogen 3.035 N/A THR 338.A N ILE 335.A O no hydrogen 3.072 N/A THR 338.A OG1 ILE 335.A O no hydrogen 2.962 N/A THR 338.A OG1 ALA 339.A O no hydrogen 3.560 N/A SER 347.A N ASP 351.A OD2 no hydrogen 3.253 N/A ILE 350.A N SER 348.A OG no hydrogen 3.196 N/A SER 353.A N ASP 351.A OD1 no hydrogen 3.038 N/A SER 353.A OG ASP 351.A OD1 no hydrogen 2.806 N/A SER 353.A OG ASP 351.A OD2 no hydrogen 3.131 N/A ASN 354.A ND2 PRO 150.A O no hydrogen 2.889 N/A PHE 355.A N SER 352.A O no hydrogen 2.989 N/A GLN 374.A N ASP 33.A OD1 no hydrogen 3.312 N/A GLN 374.A N ASP 33.A OD2 no hydrogen 3.324 N/A GLN 374.A NE2 ASP 139.A O no hydrogen 2.911 N/A LEU 375.A N GLY 372.A O no hydrogen 3.468 N/A PHE 377.A N GLN 374.A O no hydrogen 3.133 N/A ILE 378.A N LEU 375.A O no hydrogen 3.471 N/A GLY 379.A N ASP 25.A OD2 no hydrogen 3.151 N/A THR 381.A N ASP 25.A OD2 no hydrogen 3.076 N/A THR 381.A OG1 ASP 25.A OD1 no hydrogen 2.914 N/A THR 381.A OG1 ASP 25.A OD2 no hydrogen 3.361 N/A TYR 382.A N ALA 135.A O no hydrogen 2.864 N/A ARG 384.A N PHE 133.A O no hydrogen 3.245 N/A