Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7p8l_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 3.A ND1 GLU 202.A OE2 no hydrogen 2.886 N/A ILE 5.A N GLY 1.A O no hydrogen 3.023 N/A ALA 6.A N SER 2.A O no hydrogen 2.885 N/A ARG 7.A N HIS 3.A O no hydrogen 2.931 N/A ARG 7.A NH1 GLU 11.A OE2 no hydrogen 2.873 N/A ARG 7.A NH2 GLU 236.A OE2 no hydrogen 2.771 N/A ILE 8.A N MET 4.A O no hydrogen 3.021 N/A ILE 9.A N ILE 5.A O no hydrogen 2.858 N/A GLY 10.A N ALA 6.A O no hydrogen 2.820 N/A GLU 11.A N ARG 7.A O no hydrogen 2.992 N/A ILE 12.A N ILE 8.A O no hydrogen 2.915 N/A GLY 13.A N ILE 9.A O no hydrogen 2.778 N/A GLY 16.A N ILE 12.A O no hydrogen 2.936 N/A ALA 17.A N GLY 13.A O no hydrogen 2.997 N/A ARG 18.A N ILE 14.A O no hydrogen 2.772 N/A ARG 18.A NE GLU 22.A OE2 no hydrogen 3.009 N/A PHE 19.A N GLU 15.A O no hydrogen 2.980 N/A ILE 20.A N GLY 16.A O no hydrogen 3.008 N/A GLU 21.A N ALA 17.A O no hydrogen 2.869 N/A GLU 22.A N ARG 18.A O no hydrogen 2.960 N/A ASN 23.A N PHE 19.A O no hydrogen 2.880 N/A ILE 24.A N ILE 20.A O no hydrogen 2.905 N/A ASP 25.A N ILE 20.A O no hydrogen 2.899 N/A GLN 27.A N ASP 25.A OD1 no hydrogen 2.910 N/A GLN 27.A NE2 ASP 25.A OD1 no hydrogen 3.379 N/A GLN 27.A NE2 ASP 25.A OD2 no hydrogen 3.204 N/A PHE 28.A N ASP 25.A O no hydrogen 3.077 N/A LYS 29.A N ASP 25.A O no hydrogen 3.316 N/A LYS 29.A NZ ASN 23.A O no hydrogen 3.024 N/A ALA 30.A N GLU 26.A O no hydrogen 2.921 N/A LEU 31.A N GLN 27.A O no hydrogen 3.091 N/A ARG 32.A N PHE 28.A O no hydrogen 2.847 N/A ARG 32.A NH2 GLU 22.A O no hydrogen 3.011 N/A TYR 33.A N LYS 29.A O no hydrogen 3.060 N/A LEU 34.A N ALA 30.A O no hydrogen 3.018 N/A SER 35.A N LEU 31.A O no hydrogen 2.886 N/A SER 35.A OG ARG 32.A O no hydrogen 2.713 N/A LYS 36.A N TYR 33.A O no hydrogen 3.151 N/A GLY 37.A N LEU 34.A O no hydrogen 2.855 N/A SER 40.A OG.B GLU 117.A OE1.B no hydrogen 2.841 N/A THR 42.A N ASP 39.A OD1 no hydrogen 2.955 N/A THR 42.A OG1 ASP 39.A OD1 no hydrogen 3.201 N/A THR 42.A OG1 ASP 39.A OD2 no hydrogen 2.586 N/A PHE 43.A N ASP 39.A O no hydrogen 2.856 N/A VAL 44.A N SER 40.A O no hydrogen 3.102 N/A LYS 45.A N GLU 41.A O no hydrogen 3.025 N/A LEU 46.A N THR 42.A O no hydrogen 2.842 N/A VAL 47.A N PHE 43.A O no hydrogen 2.956 N/A ILE 48.A N VAL 44.A O no hydrogen 3.050 N/A ALA 49.A N LYS 45.A O no hydrogen 2.970 N/A ASN 50.A N LEU 46.A O no hydrogen 2.761 N/A SER 51.A N VAL 47.A O no hydrogen 2.947 N/A SER 51.A OG VAL 47.A O no hydrogen 2.845 N/A LEU 52.A N ILE 48.A O no hydrogen 3.086 N/A VAL 53.A N ASN 50.A O no hydrogen 3.126 N/A SER 54.A N SER 51.A O no hydrogen 3.122 N/A SER 54.A OG ASN 50.A O no hydrogen 2.660 N/A THR 58.A N PHE 93.A O no hydrogen 2.888 N/A THR 58.A OG1 ARG 92.A O no hydrogen 2.877 N/A LYS 60.A N GLN 63.A OE1 no hydrogen 2.905 N/A GLU 62.A N GLU 62.A OE1 no hydrogen 2.824 N/A TRP 64.A N LYS 60.A O no hydrogen 2.937 N/A TRP 64.A NE1 SER 54.A OG no hydrogen 2.930 N/A TRP 65.A N GLY 61.A O no hydrogen 2.911 N/A TRP 66.A N GLU 62.A O no hydrogen 3.282 N/A TRP 66.A NE1 GLU 26.A OE1 no hydrogen 2.924 N/A GLU 67.A N GLN 63.A O no hydrogen 2.955 N/A PHE 68.A N TRP 64.A O no hydrogen 2.935 N/A ALA 69.A N TRP 65.A O no hydrogen 2.967 N/A LYS 70.A N TRP 66.A O no hydrogen 2.907 N/A TYR 71.A N GLU 67.A O no hydrogen 2.937 N/A PHE 72.A N PHE 68.A O no hydrogen 3.140 N/A TYR 73.A N ALA 69.A O no hydrogen 3.227 N/A GLY 74.A N GLY 37.A O no hydrogen 2.793 N/A ARG 75.A N PHE 72.A O no hydrogen 2.987 N/A SER 79.A OG GLU 109.A OE2 no hydrogen 3.536 N/A TYR 81.A N GLU 109.A OE2 no hydrogen 2.988 N/A LEU 82.A N SER 79.A OG no hydrogen 3.048 N/A ALA 83.A N SER 79.A O no hydrogen 2.857 N/A TYR 84.A N ILE 80.A O no hydrogen 2.951 N/A TYR 84.A OH ASN 50.A OD1 no hydrogen 2.682 N/A LYS 85.A N TYR 81.A O no hydrogen 2.837 N/A GLU 86.A N LEU 82.A O no hydrogen 3.231 N/A PHE 87.A N ALA 83.A O no hydrogen 2.936 N/A LEU 88.A N TYR 84.A O no hydrogen 2.960 N/A ASN 90.A N PHE 87.A O no hydrogen 3.251 N/A ASN 90.A ND2 GLU 86.A O no hydrogen 2.768 N/A SER 91.A N LEU 88.A O no hydrogen 2.985 N/A SER 91.A OG LEU 88.A O no hydrogen 2.866 N/A ARG 92.A N GLU 67.A OE2 no hydrogen 2.774 N/A PHE 93.A N GLU 67.A OE1 no hydrogen 2.930 N/A ASN 94.A N SER 91.A OG no hydrogen 3.147 N/A ASN 94.A ND2 VAL 53.A O no hydrogen 2.932 N/A ARG 95.A N THR 58.A OG1 no hydrogen 3.240 N/A ARG 96.A NH1 GLN 56.A OE1 no hydrogen 2.948 N/A LYS 101.A N LEU 97.A O no hydrogen 3.038 N/A LYS 101.A NZ TYR 55.A O no hydrogen 2.737 N/A LYS 101.A NZ GLN 56.A O no hydrogen 3.487 N/A LYS 101.A NZ ASN 94.A OD1 no hydrogen 2.720 N/A LYS 101.A NZ ARG 96.A O no hydrogen 2.784 N/A LEU 102.A N ILE 98.A O no hydrogen 2.837 N/A SER 103.A N PRO 99.A O no hydrogen 3.055 N/A SER 103.A OG.A PRO 99.A O no hydrogen 3.199 N/A ARG 104.A N GLN 100.A O no hydrogen 3.190 N/A ARG 104.A NH1 LEU 52.A O no hydrogen 2.865 N/A ARG 104.A NH1 THR 146.A OG1 no hydrogen 2.867 N/A ILE 105.A N LYS 101.A O no hydrogen 3.189 N/A ARG 106.A N LEU 102.A O no hydrogen 2.975 N/A ARG 106.A NH1 SER 103.A OG.A no hydrogen 3.430 N/A ARG 106.A NH2 TYR 81.A OH no hydrogen 2.975 N/A ARG 107.A N SER 103.A O no hydrogen 3.024 N/A ARG 107.A NH2 LEU 138.A O no hydrogen 2.731 N/A VAL 108.A N ARG 104.A O no hydrogen 3.184 N/A VAL 108.A N ILE 105.A O no hydrogen 3.161 N/A GLU 109.A N ARG 106.A O no hydrogen 3.461 N/A LEU 112.A N VAL 108.A O no hydrogen 2.923 N/A SER 113.A N GLU 109.A O no hydrogen 3.048 N/A SER 113.A N THR 110.A O no hydrogen 3.118 N/A SER 113.A OG THR 110.A O no hydrogen 2.643 N/A THR 114.A N PHE 111.A O no hydrogen 2.971 N/A THR 114.A OG1 PHE 111.A O no hydrogen 2.711 N/A LEU 115.A N LEU 112.A O no hydrogen 3.013 N/A THR 116.A N THR 114.A O no hydrogen 2.905 N/A GLU 117.A N GLU 41.A OE2 no hydrogen 3.057 N/A ARG 119.A N THR 116.A OG1 no hydrogen 3.009 N/A ILE 120.A N THR 116.A O no hydrogen 2.899 N/A GLU 121.A N GLU 117.A O no hydrogen 2.974 N/A GLU 122.A N GLU 118.A O no hydrogen 2.885 N/A TYR 123.A N ARG 119.A O no hydrogen 2.894 N/A TYR 123.A OH SER 133.A OG no hydrogen 3.424 N/A TYR 124.A N ILE 120.A O no hydrogen 2.854 N/A GLY 125.A N GLU 121.A O no hydrogen 3.059 N/A ASP 126.A N TYR 123.A O no hydrogen 3.041 N/A SER 128.A OG GLU 171.A OE2 no hydrogen 2.527 N/A SER 129.A N ASP 126.A O no hydrogen 3.021 N/A SER 129.A N ASP 126.A OD1 no hydrogen 3.362 N/A SER 129.A OG.A ASP 126.A O no hydrogen 2.541 N/A SER 129.A OG.C ASP 126.A OD2 no hydrogen 2.641 N/A LEU 130.A N ASP 126.A O no hydrogen 3.353 N/A TRP 131.A N MET 127.A O no hydrogen 2.900 N/A TRP 131.A NE1 LYS 142.A O no hydrogen 2.744 N/A GLY 132.A N SER 128.A O no hydrogen 3.270 N/A SER 133.A N SER 129.A O no hydrogen 2.961 N/A SER 133.A OG TYR 123.A OH no hydrogen 3.424 N/A SER 133.A OG SER 129.A O no hydrogen 2.854 N/A ILE 134.A N LEU 130.A O no hydrogen 2.894 N/A ALA 135.A N TRP 131.A O no hydrogen 3.263 N/A ARG 136.A N GLY 132.A O no hydrogen 2.909 N/A ALA 137.A N SER 133.A O no hydrogen 2.998 N/A LEU 138.A N ILE 134.A O no hydrogen 3.092 N/A GLY 139.A N ARG 136.A O no hydrogen 3.207 N/A VAL 140.A N ALA 135.A O no hydrogen 3.039 N/A GLU 143.A N ASP 141.A OD1 no hydrogen 2.957 N/A SER 144.A N ASP 141.A O no hydrogen 3.142 N/A SER 144.A OG ASP 141.A O no hydrogen 2.812 N/A VAL 148.A N SER 144.A O no hydrogen 3.089 N/A PHE 149.A N GLN 145.A O no hydrogen 2.889 N/A SER 150.A N THR 146.A O no hydrogen 2.898 N/A SER 150.A OG VAL 147.A O no hydrogen 2.761 N/A VAL 151.A N VAL 147.A O no hydrogen 3.207 N/A LYS 152.A N VAL 148.A O no hydrogen 3.171 N/A LYS 152.A NZ ASP 211.A OD2 no hydrogen 2.775 N/A LYS 152.A NZ SER 212.A OG no hydrogen 2.892 N/A MET 153.A N PHE 149.A O no hydrogen 2.867 N/A PHE 154.A N SER 150.A O no hydrogen 2.843 N/A GLY 155.A N VAL 151.A O no hydrogen 2.968 N/A TYR 156.A N LYS 152.A O no hydrogen 3.080 N/A TYR 156.A OH ASP 25.A OD2 no hydrogen 2.731 N/A ALA 157.A N MET 153.A O no hydrogen 2.952 N/A ALA 158.A N PHE 154.A O no hydrogen 2.712 N/A ARG 159.A N GLY 155.A O no hydrogen 3.193 N/A ARG 159.A NE GLY 155.A O no hydrogen 3.205 N/A ARG 159.A NH1 GLU 21.A OE1 no hydrogen 2.825 N/A ARG 159.A NH1 GLU 22.A OE2 no hydrogen 3.065 N/A ARG 159.A NH2 GLU 21.A OE1 no hydrogen 2.865 N/A ILE 160.A N TYR 156.A O no hydrogen 3.333 N/A VAL 161.A N ALA 157.A O no hydrogen 3.065 N/A LEU 162.A N ALA 158.A O no hydrogen 2.817 N/A SER 163.A OG.B LEU 162.A O no hydrogen 2.806 N/A ASN 166.A N TYR 124.A OH no hydrogen 3.049 N/A ASN 166.A ND2 TYR 124.A O no hydrogen 3.205 N/A TYR 168.A N HIS 209.A NE2 no hydrogen 3.040 N/A TYR 168.A OH LYS 152.A O no hydrogen 2.680 N/A ILE 172.A N PRO 169.A O no hydrogen 3.321 N/A ASP 177.A N PRO 175.A O no hydrogen 2.948 N/A ARG 179.A N ASP 177.A OD2 no hydrogen 3.132 N/A ARG 179.A NH1 GLU 62.A OE2 no hydrogen 3.006 N/A ARG 179.A NH1 TRP 215.A O no hydrogen 2.988 N/A ARG 179.A NH2 GLU 62.A OE1 no hydrogen 2.864 N/A ARG 179.A NH2 GLU 62.A OE2 no hydrogen 3.427 N/A ILE 180.A N ASP 177.A OD1 no hydrogen 3.024 N/A VAL 181.A N ASP 177.A O no hydrogen 2.919 N/A LYS 182.A N SER 178.A O no hydrogen 2.893 N/A LEU 183.A N ARG 179.A O no hydrogen 3.043 N/A THR 184.A N ILE 180.A O no hydrogen 2.910 N/A THR 184.A OG1 ILE 180.A O no hydrogen 2.729 N/A LYS 185.A N VAL 181.A O no hydrogen 3.056 N/A LYS 186.A N LYS 182.A O no hydrogen 3.297 N/A LEU 187.A N LEU 183.A O no hydrogen 3.255 N/A LEU 187.A N THR 184.A O no hydrogen 2.939 N/A THR 188.A N THR 184.A O no hydrogen 2.930 N/A GLU 190.A N THR 188.A OG1 no hydrogen 2.971 N/A ARG 193.A NE GLU 143.A OE1 no hydrogen 2.542 N/A ARG 193.A NH2 GLU 143.A OE2 no hydrogen 2.891 N/A PHE 195.A N LYS 191.A O no hydrogen 2.972 N/A TRP 196.A N PRO 192.A O no hydrogen 2.933 N/A TRP 196.A NE1 THR 184.A OG1 no hydrogen 2.809 N/A MET 197.A N ARG 193.A O no hydrogen 2.962 N/A LYS 198.A N LYS 194.A O no hydrogen 2.994 N/A ILE 199.A N PHE 195.A O no hydrogen 3.218 N/A ALA 200.A N TRP 196.A O no hydrogen 2.861 N/A ARG 201.A N MET 197.A O no hydrogen 2.956 N/A GLU 202.A N LYS 198.A O no hydrogen 2.958 N/A SER 203.A N ILE 199.A O no hydrogen 2.872 N/A SER 203.A OG ILE 199.A O no hydrogen 2.802 N/A SER 203.A OG ALA 200.A O no hydrogen 3.255 N/A GLY 204.A N ALA 200.A O no hydrogen 2.835 N/A VAL 205.A N SER 203.A OG no hydrogen 3.147 N/A HIS 209.A ND1 GLU 21.A OE2 no hydrogen 2.820 N/A ILE 210.A N PRO 206.A O no hydrogen 2.927 N/A ASP 211.A N PRO 207.A O no hydrogen 2.852 N/A SER 212.A N LEU 208.A O no hydrogen 3.270 N/A SER 212.A OG GLU 21.A OE2 no hydrogen 2.671 N/A SER 212.A OG LEU 208.A O no hydrogen 3.223 N/A ILE 213.A N HIS 209.A O no hydrogen 3.133 N/A LEU 214.A N ILE 210.A O no hydrogen 2.934 N/A TRP 215.A N ASP 211.A O no hydrogen 2.782 N/A TRP 215.A NE1 ASP 177.A OD2 no hydrogen 2.954 N/A LEU 218.A N LEU 214.A O no hydrogen 2.825 N/A GLY 219.A N TRP 215.A O no hydrogen 3.259 N/A GLY 219.A N PRO 216.A O no hydrogen 3.133 N/A GLY 220.A N LEU 217.A O no hydrogen 2.976 N/A ALA 221.A N PRO 216.A O no hydrogen 3.117 N/A ASP 224.A N SER 222.A OG no hydrogen 3.107 N/A ALA 226.A N ILE 223.A O no hydrogen 3.074 N/A ARG 231.A N PRO 227.A O no hydrogen 2.804 N/A ARG 231.A NE ALA 226.A O no hydrogen 2.927 N/A ARG 231.A NH2 ALA 226.A O no hydrogen 2.900 N/A ASP 232.A N PRO 228.A O no hydrogen 3.072 N/A LYS 233.A N GLU 229.A O no hydrogen 3.278 N/A LYS 233.A NZ GLU 11.A O no hydrogen 2.884 N/A LEU 234.A N LEU 230.A O no hydrogen 2.896 N/A ALA 235.A N ARG 231.A O no hydrogen 2.843 N/A GLU 236.A N ASP 232.A O no hydrogen 3.028 N/A LEU 237.A N LYS 233.A O no hydrogen 2.994 N/A ILE 238.A N LEU 234.A O no hydrogen 2.854 N/A LYS 239.A N ALA 235.A O no hydrogen 3.237 N/A ILE 240.A N LEU 237.A O no hydrogen 2.897 N/A ILE 241.A N LEU 237.A O no hydrogen 3.013 N/A ARG 242.A N ILE 238.A O no hydrogen 2.903 N/A ARG 242.A NE LEU 217.A O no hydrogen 2.858 N/A ARG 242.A NH2 LEU 217.A O no hydrogen 2.862 N/A ARG 242.A NH2 ALA 221.A O no hydrogen 2.820 N/A